LOCUS       DAVMCN010000001       143046 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVMCN010000001 DAVMCN010000000
VERSION     DAVMCN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 143046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 143046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..143046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.001"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            153..941
                     /gene="codY"
                     /locus_tag="VYP85_000001"
     CDS             153..941
                     /gene="codY"
                     /locus_tag="VYP85_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1880581.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            941..1516
                     /locus_tag="VYP85_000002"
     CDS             941..1516
                     /locus_tag="VYP85_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1880582.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1597..1682
                     /locus_tag="VYP85_000003"
     tRNA            1597..1682
                     /locus_tag="VYP85_000003"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1631..1633,aa:Leu,seq:aag)
     gene            1965..3095
                     /gene="ugpC"
                     /locus_tag="VYP85_000004"
     CDS             1965..3095
                     /gene="ugpC"
                     /locus_tag="VYP85_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1880583.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3217..3387)
                     /locus_tag="VYP85_000005"
     CDS             complement(3217..3387)
                     /locus_tag="VYP85_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880584.1"
                     /translation="MEIKEQTRKLAVSYSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEYKEHHNIDV"
     gene            3605..4363
                     /locus_tag="VYP85_000006"
     CDS             3605..4363
                     /locus_tag="VYP85_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1880585.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4450..4962
                     /locus_tag="VYP85_000007"
     CDS             4450..4962
                     /locus_tag="VYP85_000007"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1880586.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5144..6088
                     /locus_tag="VYP85_000008"
     CDS             5144..6088
                     /locus_tag="VYP85_000008"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1880587.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6097..6774
                     /locus_tag="VYP85_000009"
     CDS             6097..6774
                     /locus_tag="VYP85_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1880588.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6872..7630
                     /locus_tag="VYP85_000010"
     CDS             6872..7630
                     /locus_tag="VYP85_000010"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1880589.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALSGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7668..9173
                     /gene="lytC"
                     /locus_tag="VYP85_000011"
     CDS             7668..9173
                     /gene="lytC"
                     /locus_tag="VYP85_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1880590.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYLKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9670..10188
                     /locus_tag="VYP85_000012"
     CDS             9670..10188
                     /locus_tag="VYP85_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1880591.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10318..10824
                     /locus_tag="VYP85_000013"
     CDS             10318..10824
                     /locus_tag="VYP85_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1880592.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10824..10994
                     /locus_tag="VYP85_000014"
     CDS             10824..10994
                     /locus_tag="VYP85_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880593.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            11026..12258
                     /gene="clpX"
                     /locus_tag="VYP85_000015"
     CDS             11026..12258
                     /gene="clpX"
                     /locus_tag="VYP85_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1880594.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12267..12854
                     /locus_tag="VYP85_000016"
     CDS             12267..12854
                     /locus_tag="VYP85_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1880595.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12865..13245
                     /locus_tag="VYP85_000017"
     CDS             12865..13245
                     /locus_tag="VYP85_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1880596.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13297..14187
                     /gene="rapZ"
                     /locus_tag="VYP85_000018"
     CDS             13297..14187
                     /gene="rapZ"
                     /locus_tag="VYP85_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1880597.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14184..15161
                     /locus_tag="VYP85_000019"
     CDS             14184..15161
                     /locus_tag="VYP85_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1880598.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFASHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQAILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15158..16069
                     /gene="whiA"
                     /locus_tag="VYP85_000020"
     CDS             15158..16069
                     /gene="whiA"
                     /locus_tag="VYP85_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1880599.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16157..17284)
                     /locus_tag="VYP85_000021"
     CDS             complement(16157..17284)
                     /locus_tag="VYP85_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1880600.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSENVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(17438..18388)
                     /locus_tag="VYP85_000022"
     CDS             complement(17438..18388)
                     /locus_tag="VYP85_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEV1880601.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(18537..19328)
                     /locus_tag="VYP85_000023"
     CDS             complement(18537..19328)
                     /locus_tag="VYP85_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1880602.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAVIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            complement(19572..20261)
                     /locus_tag="VYP85_000024"
     CDS             complement(19572..20261)
                     /locus_tag="VYP85_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV1880603.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            20468..20632
                     /locus_tag="VYP85_000025"
     CDS             20468..20632
                     /locus_tag="VYP85_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880604.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            20651..20866
                     /locus_tag="VYP85_000026"
     CDS             20651..20866
                     /locus_tag="VYP85_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1880605.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            20898..21098
                     /locus_tag="VYP85_000027"
     CDS             20898..21098
                     /locus_tag="VYP85_000027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880606.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(21497..21688)
                     /locus_tag="VYP85_000028"
     CDS             complement(21497..21688)
                     /locus_tag="VYP85_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880607.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLKKYHEWLHS"
     gene            21947..22117
                     /locus_tag="VYP85_000029"
     CDS             21947..22117
                     /locus_tag="VYP85_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880608.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(22110..22349)
                     /locus_tag="VYP85_000030"
     CDS             complement(22110..22349)
                     /locus_tag="VYP85_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880609.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            22467..22739
                     /locus_tag="VYP85_000031"
     CDS             22467..22739
                     /locus_tag="VYP85_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880610.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            22736..22951
                     /locus_tag="VYP85_000032"
     CDS             22736..22951
                     /locus_tag="VYP85_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880611.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            22930..23118
                     /locus_tag="VYP85_000033"
     CDS             22930..23118
                     /locus_tag="VYP85_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880612.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            23130..23471
                     /locus_tag="VYP85_000034"
     CDS             23130..23471
                     /locus_tag="VYP85_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880613.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            23472..23702
                     /locus_tag="VYP85_000035"
     CDS             23472..23702
                     /locus_tag="VYP85_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880614.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            23716..24438
                     /locus_tag="VYP85_000036"
     CDS             23716..24438
                     /locus_tag="VYP85_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1880615.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            24431..24913
                     /locus_tag="VYP85_000037"
     CDS             24431..24913
                     /locus_tag="VYP85_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEV1880616.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            24913..25272
                     /locus_tag="VYP85_000038"
     CDS             24913..25272
                     /locus_tag="VYP85_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880617.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            25272..25757
                     /locus_tag="VYP85_000039"
     CDS             25272..25757
                     /locus_tag="VYP85_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880618.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            25720..26913
                     /locus_tag="VYP85_000040"
     CDS             25720..26913
                     /locus_tag="VYP85_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEV1880619.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEDIEKIENATENNGFETKF
                     YPVTVKAGNPEKLAEFRQLNLVTVGDKTAMAKQSFGRKTFERYLNQTGVIVDFPKLKP
                     VNADTPLMLKLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            26932..27249
                     /locus_tag="VYP85_000041"
     CDS             26932..27249
                     /locus_tag="VYP85_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880620.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            27249..28076
                     /locus_tag="VYP85_000042"
     CDS             27249..28076
                     /locus_tag="VYP85_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1880621.1"
                     /translation="MAFTLPVNKPQVPVDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            28096..28599
                     /locus_tag="VYP85_000043"
     CDS             28096..28599
                     /locus_tag="VYP85_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880622.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DDDDLPF"
     gene            28772..29593
                     /locus_tag="VYP85_000044"
     CDS             28772..29593
                     /locus_tag="VYP85_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEV1880623.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLINFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            29596..30933
                     /locus_tag="VYP85_000045"
     CDS             29596..30933
                     /locus_tag="VYP85_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1880624.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKN"
     gene            31233..31388
                     /locus_tag="VYP85_000046"
     CDS             31233..31388
                     /locus_tag="VYP85_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880625.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            31385..32080
                     /locus_tag="VYP85_000047"
     CDS             31385..32080
                     /locus_tag="VYP85_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1880626.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREVWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELEDANFGW
                     VFDCPGIEIEEVE"
     gene            32238..32498
                     /locus_tag="VYP85_000048"
     CDS             32238..32498
                     /locus_tag="VYP85_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV1880627.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            32498..32956
                     /locus_tag="VYP85_000049"
     CDS             32498..32956
                     /locus_tag="VYP85_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880628.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            33004..33072
                     /locus_tag="VYP85_000050"
                     /pseudo
     CDS             33004..33072
                     /locus_tag="VYP85_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            33069..33506
                     /locus_tag="VYP85_000051"
     CDS             33069..33506
                     /locus_tag="VYP85_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880629.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            33503..33874
                     /locus_tag="VYP85_000052"
     CDS             33503..33874
                     /locus_tag="VYP85_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880630.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFVR"
     gene            33944..34366
                     /locus_tag="VYP85_000053"
     CDS             33944..34366
                     /locus_tag="VYP85_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1880631.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWIDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRLINKLKNPKSRSILRVTYITK
                     MYVDDICDKMEISRTTFYTWRNMAISELNEVLERMELN"
     gene            34452..34534
                     /locus_tag="VYP85_000054"
     tRNA            34452..34534
                     /locus_tag="VYP85_000054"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34483..34485,aa:Tyr,seq:gta)
     gene            34784..35263
                     /locus_tag="VYP85_000055"
     CDS             34784..35263
                     /locus_tag="VYP85_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV1880632.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDINVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            35241..36539
                     /locus_tag="VYP85_000056"
     CDS             35241..36539
                     /locus_tag="VYP85_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV1880633.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYVIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            36551..38020
                     /locus_tag="VYP85_000057"
     CDS             36551..38020
                     /locus_tag="VYP85_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1880634.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRSVR"
     gene            37929..39479
                     /locus_tag="VYP85_000058"
     CDS             37929..39479
                     /locus_tag="VYP85_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV1880635.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPENEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDVKNEIQDYKKSDKTVSRYNTPKLFSDVSNAWDEIGRGGLSKEQLV
                     DLLESEYELGNFSSDIAKLIGVSSAYIDVSSLATSLVRHGQQYSLDEFMLIKEAVQKP
                     YLILDNSERVEKSIISYVKIPNKDKVIMEAVMVPRDEMLVIHFNKVGIRQVKKNEKNM
                     STLYKKGK"
     gene            39630..39803
                     /locus_tag="VYP85_000059"
     CDS             39630..39803
                     /locus_tag="VYP85_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880636.1"
                     /translation="MDTARIGITNVEFSGTGENDSATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            39948..40160
                     /locus_tag="VYP85_000060"
     CDS             39948..40160
                     /locus_tag="VYP85_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880637.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            40330..40914
                     /locus_tag="VYP85_000061"
     CDS             40330..40914
                     /locus_tag="VYP85_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV1880638.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            40921..41766
                     /locus_tag="VYP85_000062"
     CDS             40921..41766
                     /locus_tag="VYP85_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV1880639.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            41778..41960
                     /locus_tag="VYP85_000063"
     CDS             41778..41960
                     /locus_tag="VYP85_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV1880640.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            41950..42138
                     /locus_tag="VYP85_000064"
     CDS             41950..42138
                     /locus_tag="VYP85_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880641.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            42140..42451
                     /locus_tag="VYP85_000065"
     CDS             42140..42451
                     /locus_tag="VYP85_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV1880642.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTDLLQRIRMHRLARVAGHVFEA
                     E"
     gene            42432..42770
                     /locus_tag="VYP85_000066"
     CDS             42432..42770
                     /locus_tag="VYP85_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880643.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            42745..43260
                     /locus_tag="VYP85_000067"
     CDS             42745..43260
                     /locus_tag="VYP85_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV1880644.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            43257..43625
                     /locus_tag="VYP85_000068"
     CDS             43257..43625
                     /locus_tag="VYP85_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880645.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGIVDLHSELVFQFRMEN"
     gene            43628..44041
                     /locus_tag="VYP85_000069"
     CDS             43628..44041
                     /locus_tag="VYP85_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1880646.1"
                     /translation="MLANGITLSYGETKDSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVIFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSNLTFTDGIGG"
     gene            44046..44426
                     /locus_tag="VYP85_000070"
     CDS             44046..44426
                     /locus_tag="VYP85_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880647.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            44465..44815
                     /locus_tag="VYP85_000071"
     CDS             44465..44815
                     /locus_tag="VYP85_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880648.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            44802..48335
                     /locus_tag="VYP85_000072"
     CDS             44802..48335
                     /locus_tag="VYP85_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880649.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIVTDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAKFAHSVATGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTVWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTNALSSVSNWFGEMFTNAYNAVKDAFSSIGDFFKGVWDTVKSIFVNAGQMVGE
                     AVGGAFKSAVNAVLGTIENVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARG
                     GIVDSPTIAMIGEAGKEAVVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDI
                     VIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            48344..48694
                     /locus_tag="VYP85_000073"
     CDS             48344..48694
                     /locus_tag="VYP85_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880650.1"
                     /translation="MAQLTINGVAVKPPKYFQVGIQDIDGETGRNANGDMMRDRITTK
                     RKLDCEWGMMTQGELSQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            49746..50322
                     /locus_tag="VYP85_000074"
                     /pseudo
     CDS             49746..50322
                     /locus_tag="VYP85_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860112.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            51327..55085
                     /locus_tag="VYP85_000075"
                     /pseudo
     CDS             51327..55085
                     /locus_tag="VYP85_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            55179..55382
                     /locus_tag="VYP85_000076"
     CDS             55179..55382
                     /locus_tag="VYP85_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880651.1"
                     /translation="MNTEQLNQALRMTISEISITSTNSMIESNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            55385..55735
                     /locus_tag="VYP85_000077"
     CDS             55385..55735
                     /locus_tag="VYP85_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880652.1"
                     /translation="MAETNQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            55744..56043
                     /locus_tag="VYP85_000078"
     CDS             55744..56043
                     /locus_tag="VYP85_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880653.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEIEKGE"
     gene            56047..56382
                     /locus_tag="VYP85_000079"
     CDS             56047..56382
                     /locus_tag="VYP85_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1880654.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            56382..57338
                     /gene="lytA"
                     /locus_tag="VYP85_000080"
     CDS             56382..57338
                     /gene="lytA"
                     /locus_tag="VYP85_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1880655.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(57591..58556)
                     /locus_tag="VYP85_000081"
     CDS             complement(57591..58556)
                     /locus_tag="VYP85_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1880656.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            58692..59549
                     /locus_tag="VYP85_000082"
     CDS             58692..59549
                     /locus_tag="VYP85_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1880657.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            59536..60315
                     /locus_tag="VYP85_000083"
     CDS             59536..60315
                     /locus_tag="VYP85_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1880658.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            60339..61691
                     /locus_tag="VYP85_000084"
     CDS             60339..61691
                     /locus_tag="VYP85_000084"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1880659.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            61765..62139
                     /locus_tag="VYP85_000085"
     CDS             61765..62139
                     /locus_tag="VYP85_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1880660.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            62141..62989
                     /locus_tag="VYP85_000086"
     CDS             62141..62989
                     /locus_tag="VYP85_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1880661.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            63255..64022
                     /locus_tag="VYP85_000087"
     CDS             63255..64022
                     /locus_tag="VYP85_000087"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1880662.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            64034..65218
                     /locus_tag="VYP85_000088"
     CDS             64034..65218
                     /locus_tag="VYP85_000088"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1880663.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            65215..67086
                     /locus_tag="VYP85_000089"
     CDS             65215..67086
                     /locus_tag="VYP85_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1880664.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKELSGGVAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(67229..68413)
                     /gene="mntE"
                     /locus_tag="VYP85_000090"
     CDS             complement(67229..68413)
                     /gene="mntE"
                     /locus_tag="VYP85_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1880665.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISASIMFMVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTTIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            68717..71413
                     /locus_tag="VYP85_000091"
     CDS             68717..71413
                     /locus_tag="VYP85_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1880666.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAMDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVILANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            71426..72217
                     /gene="yghU"
                     /locus_tag="VYP85_000092"
     CDS             71426..72217
                     /gene="yghU"
                     /locus_tag="VYP85_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1880667.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            72333..72743
                     /locus_tag="VYP85_000093"
     CDS             72333..72743
                     /locus_tag="VYP85_000093"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1880668.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            72755..74350
                     /locus_tag="VYP85_000094"
     CDS             72755..74350
                     /locus_tag="VYP85_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880669.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            74517..74681
                     /locus_tag="VYP85_000095"
     CDS             74517..74681
                     /locus_tag="VYP85_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1880670.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            74760..75488
                     /gene="yaaA"
                     /locus_tag="VYP85_000096"
     CDS             74760..75488
                     /gene="yaaA"
                     /locus_tag="VYP85_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1880671.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(75766..76314)
                     /locus_tag="VYP85_000097"
     CDS             complement(75766..76314)
                     /locus_tag="VYP85_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1880672.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            76635..77123
                     /locus_tag="VYP85_000098"
     CDS             76635..77123
                     /locus_tag="VYP85_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1880673.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEKADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            77120..78307
                     /locus_tag="VYP85_000099"
     CDS             77120..78307
                     /locus_tag="VYP85_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1880674.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            78300..78665
                     /locus_tag="VYP85_000100"
     CDS             78300..78665
                     /locus_tag="VYP85_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1880675.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            78681..80027
                     /gene="asnS"
                     /locus_tag="VYP85_000101"
     CDS             78681..80027
                     /gene="asnS"
                     /locus_tag="VYP85_000101"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1880676.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            80180..80470
                     /locus_tag="VYP85_000102"
     CDS             80180..80470
                     /locus_tag="VYP85_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1880677.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            80482..80952
                     /gene="ssbA"
                     /locus_tag="VYP85_000103"
     CDS             80482..80952
                     /gene="ssbA"
                     /locus_tag="VYP85_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1880678.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            80984..81223
                     /locus_tag="VYP85_000104"
     CDS             80984..81223
                     /locus_tag="VYP85_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1880679.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            81518..82918
                     /locus_tag="VYP85_000105"
     CDS             81518..82918
                     /locus_tag="VYP85_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1880680.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            82920..83279
                     /locus_tag="VYP85_000106"
     CDS             82920..83279
                     /locus_tag="VYP85_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1880681.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            83333..84082
                     /locus_tag="VYP85_000107"
     CDS             83333..84082
                     /locus_tag="VYP85_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1880682.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            84072..84371
                     /locus_tag="VYP85_000108"
     CDS             84072..84371
                     /locus_tag="VYP85_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1880683.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            84442..85377
                     /locus_tag="VYP85_000109"
     CDS             84442..85377
                     /locus_tag="VYP85_000109"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1880684.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            85463..85975
                     /locus_tag="VYP85_000110"
     CDS             85463..85975
                     /locus_tag="VYP85_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1880685.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            86000..86608
                     /locus_tag="VYP85_000111"
     CDS             86000..86608
                     /locus_tag="VYP85_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1880686.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKYQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            86709..86906
                     /locus_tag="VYP85_000112"
     CDS             86709..86906
                     /locus_tag="VYP85_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1880687.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(86949..88394)
                     /locus_tag="VYP85_000113"
     CDS             complement(86949..88394)
                     /locus_tag="VYP85_000113"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1880688.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISNYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            88500..90122
                     /locus_tag="VYP85_000114"
     CDS             88500..90122
                     /locus_tag="VYP85_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1880689.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            90325..92283
                     /locus_tag="VYP85_000115"
     CDS             90325..92283
                     /locus_tag="VYP85_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1880690.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQLIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            92455..92988
                     /locus_tag="VYP85_000116"
                     /pseudo
     CDS             92455..92988
                     /locus_tag="VYP85_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            92997..93536
                     /locus_tag="VYP85_000117"
     CDS             92997..93536
                     /locus_tag="VYP85_000117"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880691.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            93572..94117
                     /locus_tag="VYP85_000118"
     CDS             93572..94117
                     /locus_tag="VYP85_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1880692.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            94274..95368
                     /locus_tag="VYP85_000119"
     CDS             94274..95368
                     /locus_tag="VYP85_000119"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1880693.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            95376..96542
                     /locus_tag="VYP85_000120"
     CDS             95376..96542
                     /locus_tag="VYP85_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1880694.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQIYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            96635..99733
                     /locus_tag="VYP85_000121"
     CDS             96635..99733
                     /locus_tag="VYP85_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1880695.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQVLVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            99781..100398
                     /locus_tag="VYP85_000122"
     CDS             99781..100398
                     /locus_tag="VYP85_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1880696.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            100409..101743
                     /locus_tag="VYP85_000123"
     CDS             100409..101743
                     /locus_tag="VYP85_000123"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1880697.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            101753..102217
                     /locus_tag="VYP85_000124"
     CDS             101753..102217
                     /locus_tag="VYP85_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1880698.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            102214..102708
                     /locus_tag="VYP85_000125"
     CDS             102214..102708
                     /locus_tag="VYP85_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1880699.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            102789..104444
                     /gene="mltG"
                     /locus_tag="VYP85_000126"
     CDS             102789..104444
                     /gene="mltG"
                     /locus_tag="VYP85_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1880700.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            104515..104997
                     /gene="greA"
                     /locus_tag="VYP85_000127"
     CDS             104515..104997
                     /gene="greA"
                     /locus_tag="VYP85_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1880701.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            105370..105768
                     /locus_tag="VYP85_000128"
     CDS             105370..105768
                     /locus_tag="VYP85_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1880702.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            106202..107152
                     /locus_tag="VYP85_000129"
     CDS             106202..107152
                     /locus_tag="VYP85_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1880703.1"
                     /translation="MLQKANKGKSNREIASLLGKAPQTIHTEIKRRTVRQCLGKGRFK
                     EVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQKFSPEMMVMAKGVNVGIST
                     IYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQSIEQRLEAINFRLENGHYE
                     IDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADN
                     GTEFNRLSNVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEK
                     WINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
     gene            107227..107427
                     /locus_tag="VYP85_000130"
     CDS             107227..107427
                     /locus_tag="VYP85_000130"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1880704.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            107462..108178
                     /gene="atpB"
                     /locus_tag="VYP85_000131"
     CDS             107462..108178
                     /gene="atpB"
                     /locus_tag="VYP85_000131"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1880705.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            108192..108686
                     /gene="atpF"
                     /locus_tag="VYP85_000132"
     CDS             108192..108686
                     /gene="atpF"
                     /locus_tag="VYP85_000132"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1880706.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            108686..109222
                     /locus_tag="VYP85_000133"
     CDS             108686..109222
                     /locus_tag="VYP85_000133"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1880707.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            109237..110742
                     /locus_tag="VYP85_000134"
     CDS             109237..110742
                     /locus_tag="VYP85_000134"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1880708.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            110758..111636
                     /locus_tag="VYP85_000135"
     CDS             110758..111636
                     /locus_tag="VYP85_000135"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1880709.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            111722..113128
                     /gene="atpD"
                     /locus_tag="VYP85_000136"
     CDS             111722..113128
                     /gene="atpD"
                     /locus_tag="VYP85_000136"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1880710.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            113139..113558
                     /locus_tag="VYP85_000137"
     CDS             113139..113558
                     /locus_tag="VYP85_000137"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1880711.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(113603..114616)
                     /locus_tag="VYP85_000138"
     CDS             complement(113603..114616)
                     /locus_tag="VYP85_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1880712.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            114760..115926
                     /locus_tag="VYP85_000139"
     CDS             114760..115926
                     /locus_tag="VYP85_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1880713.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            115916..117145
                     /locus_tag="VYP85_000140"
     CDS             115916..117145
                     /locus_tag="VYP85_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1880714.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            117291..117932
                     /locus_tag="VYP85_000141"
     CDS             117291..117932
                     /locus_tag="VYP85_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1880715.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            117942..118571
                     /locus_tag="VYP85_000142"
     CDS             117942..118571
                     /locus_tag="VYP85_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1880716.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            118584..119420
                     /locus_tag="VYP85_000143"
     CDS             118584..119420
                     /locus_tag="VYP85_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1880717.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(119698..120045)
                     /locus_tag="VYP85_000144"
     CDS             complement(119698..120045)
                     /locus_tag="VYP85_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1880718.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(120156..121874)
                     /locus_tag="VYP85_000145"
     CDS             complement(120156..121874)
                     /locus_tag="VYP85_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1880719.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLVDGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            122108..122434
                     /locus_tag="VYP85_000146"
     CDS             122108..122434
                     /locus_tag="VYP85_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1880720.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            122421..122954
                     /locus_tag="VYP85_000147"
     CDS             122421..122954
                     /locus_tag="VYP85_000147"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1880721.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            123312..123566
                     /locus_tag="VYP85_000148"
     CDS             123312..123566
                     /locus_tag="VYP85_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880722.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            123677..124783
                     /locus_tag="VYP85_000149"
     CDS             123677..124783
                     /locus_tag="VYP85_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1880723.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            124741..125262
                     /locus_tag="VYP85_000150"
     CDS             124741..125262
                     /locus_tag="VYP85_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1880724.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            125485..126354
                     /locus_tag="VYP85_000151"
     CDS             125485..126354
                     /locus_tag="VYP85_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1880725.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            127265..128461
                     /gene="tuf"
                     /locus_tag="VYP85_000152"
     CDS             127265..128461
                     /gene="tuf"
                     /locus_tag="VYP85_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1880726.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            128845..129894
                     /locus_tag="VYP85_000153"
                     /pseudo
     CDS             128845..129894
                     /locus_tag="VYP85_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(129958..131040)
                     /locus_tag="VYP85_000154"
     CDS             complement(129958..131040)
                     /locus_tag="VYP85_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1880727.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(131037..132014)
                     /locus_tag="VYP85_000155"
     CDS             complement(131037..132014)
                     /locus_tag="VYP85_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1880728.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            132247..132624
                     /locus_tag="VYP85_000156"
                     /pseudo
     CDS             132247..132624
                     /locus_tag="VYP85_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            132859..134250
                     /locus_tag="VYP85_000157"
     CDS             132859..134250
                     /locus_tag="VYP85_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1880729.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            134364..135206
                     /locus_tag="VYP85_000158"
     CDS             134364..135206
                     /locus_tag="VYP85_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1880730.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSITISRIQANLDCFGIELSHKERETLKTIAVQLGAPRVD
                     DVDF"
     gene            135479..136240
                     /locus_tag="VYP85_000159"
     CDS             135479..136240
                     /locus_tag="VYP85_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1880731.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDLNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            136435..137352
                     /gene="glyQ"
                     /locus_tag="VYP85_000160"
     CDS             136435..137352
                     /gene="glyQ"
                     /locus_tag="VYP85_000160"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1880732.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            137564..139600
                     /locus_tag="VYP85_000161"
     CDS             137564..139600
                     /locus_tag="VYP85_000161"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1880733.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            139642..139899
                     /locus_tag="VYP85_000162"
     CDS             139642..139899
                     /locus_tag="VYP85_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1880734.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(140122..141366)
                     /locus_tag="VYP85_000163"
     CDS             complement(140122..141366)
                     /locus_tag="VYP85_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1880735.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(141385..141990)
                     /locus_tag="VYP85_000164"
     CDS             complement(141385..141990)
                     /locus_tag="VYP85_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1880736.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(142050..142973)
                     /locus_tag="VYP85_000165"
     CDS             complement(142050..142973)
                     /locus_tag="VYP85_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1880737.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
BASE COUNT        44115 a        25869 c        32109 g        40953 t
ORIGIN      
        1 acttgtcaat agaaaaggaa caatttaatt aaaaatattc tggtttttaa ttaaattgta
       61 agtcaatgca agtcaataag gaattttcag ataattattg aaaaagagac gtttttatgt
      121 tataatgata gcgattaaat tcgaggtgaa aaatggcaca tttattagaa aaaactagaa
      181 aaattacatc aattttgaaa cgctcagagg agcagttgca ggatgagctc ccttacaacg
      241 ctattacgcg tcagttagcg gatattattc attgcaatgc ctgcattatc aatagtaagg
      301 gacgtctgct tggctatttt atgcgttata aaacaaatac agatcgcgta gagcaattct
      361 tccaaactaa gattttccca gatgactacg ttcaaggggc taatatgatt tacgaaacag
      421 aagcaaactt gcctgttgag catgatatga gtattttccc tgttgagagt agagatgatt
      481 ttccagatgg cttgacgact attgcaccga ttcatgtatc ggggattcgc cttggttctt
      541 tgattatttg gcgtaatgat aaaaaattcg aagatgagga cttggttctt gttgagattg
      601 ccagtaccgt tgttgggatt cagcttctta acttccaacg tgaagaagat gagaaaaata
      661 ttcgtcgtcg tactgctgtc accatggcgg tcaataccct ttcttactcc gaactccgtg
      721 ctgtttcagc aattttaggg gaattaaatg gaaatgaagg gaagttgact gcgtcagtga
      781 ttgcagatcg tatcggaatc actcgctctg tgattgtcaa tgctcttcgt aaacttgagt
      841 ctgcggggat tattgaaagt cgctcacttg gaatgaaggg aacctatctt aaggtcttga
      901 tttcagatat ttttgaagaa gtgaagaaaa gagattacta atgacaaagg ctttaatttc
      961 gattgattat acagaagatt ttgttgctga tagtgggaaa ctaacagcag gtgctccagc
     1021 tcaggcgatt tcggatgcca tcagcaaggt aactcgatta gcttttgaac gaggagatta
     1081 tatcttcttt actattgatg ctcatgaaga aaacgattgt ttccatccgg aaagtaagtt
     1141 atttcctcct cataatctga ttgggacgag tggacggaat ttatatggag atttggggat
     1201 cttttatcaa gagcatggtt cagacagtcg tgtcttttgg atggataaac gccattactc
     1261 agctttttca gggactgacc tagatattcg tttgagagag cgtagagtgt ctaccgttat
     1321 cttaacaggt gtcttgacgg atatctgtgt cctacataca gctatagatg cctataatct
     1381 aggatatgac atcgagattg ttaaaccagc tgttgcttcc atctggcctg aaaatcatca
     1441 atttgcccta ggtcatttca aaaatacact cggagctaag ttagtagatg aaaatctaaa
     1501 tgaactttct gagtaacctg gttggtgaaa atgaaaaaat ttgaaaaaag tgttgacaag
     1561 catcccaaaa gttgatatac tagtaaagta atcgacgcgg ggatggcgga attggcagac
     1621 gcgcaggact aaggatcctg tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg
     1681 cataggaaaa gagttagcta aagctagctc ttttgtattt ctctaaaaaa ttagaatcca
     1741 gtcaaatgta gtggagaatc agcgaaaata tgggaaaact gatccttgtt tctgcttttg
     1801 tcatagaaga ataataaaga ttatcttctt caaattctcc gatattctct aaagttttgt
     1861 gcaagttgca cagaactttt ttattttttt ggtcatcttg ccatagaaaa ataaagcgtt
     1921 ttcatctata atataattat caaaagacaa aaggagttca cctcatggta gaattgaatc
     1981 ttaaaaatat ttacaaaaaa tatccaaaca gcgaacacta ttcagttgaa gatttcaact
     2041 tgaacatcaa agataaagaa tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa
     2101 ctacactccg tatgattgct ggtcttgaag acatcacaga aggtactgca tctatcgatg
     2161 gcgtggttgt caacgacgta gctccaaaag accgtgatat cgccatggta ttccaaaact
     2221 acgctcttta cccacacatg actgtttatg acaacatggc tttcggtttg aaattgcgta
     2281 aatacagcaa agaagacatt aacaaacgtg ttcaagaagc agctgaaata cttggattga
     2341 aagaattctt ggaacgtaaa ccggctgacc tttcaggtgg tcaacgtcaa cgtgttgcca
     2401 tggggcgtgc gattgtccgt gatgcgaaag tattcttgat ggacgaacct ttgtcaaact
     2461 tggatgccaa acttcgtgta tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg
     2521 gagctacaac tatctatgta actcacgacc aaacagaagc gatgacactt gcagaccgta
     2581 tcgttattat gtcagctact aagaaccctg ctggtacagg tactatcgga cgtgtagaac
     2641 aaatcggtac tcctcaagaa gtttacaaaa atccagttaa caaattcgtt gcaggattca
     2701 tcggaagccc agctatgaac ttcatcaacg tgaaattggt tggtagcgaa attgtttctg
     2761 acggtttccg tttgaaagtg ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg
     2821 aaggaaaaga attgatcttt ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc
     2881 ttgaaacatt cccagactgt gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt
     2941 cagaatctca cctttactgc caagttggta aagacgagtt tgttgcaaaa gttgatgctc
     3001 gtgactactt gcaaacaggt gcaacagttg agcttggatt tgacttgaac aaagcacact
     3061 tcttcgatgt agaaactgaa aaaacaatct actaaaataa ataaaattca aagcactaca
     3121 agaaaagata tctctttatc aattgtagtg gagagatatc agttaatcta gggagagaaa
     3181 caaaatgctt ctctcctttt tgctagggaa gtcatattat acatctatat tgtgatgctc
     3241 tttatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt acgtatgatt
     3301 actgacttcg tcagttttat ctgcaacctc aaagctgtac tttgagtagc ttacggctag
     3361 tttcctagtt tgctctttga tttccattga gtattatttg tgggtaccat ctacaagtga
     3421 agctatatgc gtaaactacg tgagcaattg aattcgaact agagaggtaa taataaattt
     3481 atgctatagt tatggtgact tgtatgcttt tgattctagt ttatcaaata atagattaga
     3541 attgtcagat aatatcattt tgtgtcattt tgtgttataa tgaagaaaaa acagaggtgt
     3601 tcaaatgtca gaagcaggtc ataagttttt agcaaaattg gggaaaaaac gcttacgtcc
     3661 aggtggaaag cgtgccacag attggttaat tgcagaagga ggattttcaa aagaaaagag
     3721 aatactagag gttgcgtgta ataggggaac tacagcaatt gagttggcac agcgttttgg
     3781 ttgcaagata actgctgttg atatggatgc tcaagcttta gaagtggcta aaaaatctgc
     3841 tggaacggca ggtgttgctc atttaatcag ttttgaaaga gcaaatgcaa tgaaacttcc
     3901 ttatcaagat gctagttttg atattgttat aaatgaagct atgctgacta tgcaagccga
     3961 tcaagctaag aaaaaatgtg taatggaata tctaagggta ttaaaacctg gaggtcttct
     4021 cttgacacat gatgtgcttc ttaaggaagc taaagagtct atcagacagg aattatcaca
     4081 agcaattcat gtaaatgtag gtcctttaac tcaagatggt tgggaacagg tgatgataga
     4141 atcaggttat tgtgatgtga aagtattgac tggtgaaatg acattaatga aattatcggg
     4201 tatgatttat gacgaaggtt ggctaggaac tttgaaaatt tgtgtaaatg cttgtaaaaa
     4261 ggagaataga aagcagtttt taactatgta taaaatgttt gctaagaata aacagaaatt
     4321 gggctttatt gcgatggcta gttataaatc gtcaaaacgt tagataatta ttgaagttaa
     4381 cttttccttt tttctttctt aaaaaatatg ctataataga gagtaaaaaa ctttgaaaga
     4441 aagaaaaaga tgaatttaaa agattacatt gcaacaattg aaaattatcc aaaggaaggc
     4501 attaccttcc gtgatattag tcctttgatg gctgatggaa atgcttatag ctacgctgtt
     4561 cgtgaaatcg ttcagtatgc tactgacaag aaagtcgaca tgatcgtggg acctgaagct
     4621 cgtggattta tcgtgggttg tccagttgcc tttgagttgg gaattggttt tgctcctgtt
     4681 cgtaagccag gtaaattgcc acgcgaagtt atttctgctg actatgaaaa agagtacggt
     4741 gtcgatacct tgactatgca cgcggatgcc attaagccag gtcaacgtgt tcttattgta
     4801 gatgaccttt tggcgacagg tggaactgtt aaggcaacta tcgagatgat tgaaaaactt
     4861 ggtggtgtta tggcaggttg tgccttcctt gttgaattgg atgaattgaa cggccgtgaa
     4921 aaaatcggtg actacgacta caaagttctt atgcattatt aatgaaaaca gtccctaggg
     4981 ctgttttctc tacactagga tataaaaata gactataact agttagagaa aaactataat
     5041 tgaaaactat atcttcttgc agtataataa aaggactaag tgtttgagat ttgtcttcaa
     5101 acacatgcaa ttattcctga gagagtacag ttaggagagg gttatgccga ttcgaattga
     5161 taaaaaattg ccagctgttg agattttacg gacagagaat atctttgtca tggatgatca
     5221 acgtgctgcc caccaagata tccgtccttt gaagatttta attttaaatc tcatgccaca
     5281 gaaaatggtc acagagaccc agttgttgcg ccacttggct aatacacccc tacaactgga
     5341 tattgatttt ctctatatgg agagccaccg ttctaaaaca actcgttcag agcacatgga
     5401 gaccttctat aaaacttttc ctgaagtcaa ggatgagtat tttgatggga tgatcatcac
     5461 gggtgctcca gttgagcatt taccatttga ggaagtggac tattgggagg aatttagaca
     5521 gatgcttgag tggtctaaga ctcatgtcta ttcgaccctt catatctgtt ggggagctca
     5581 ggctgggctt tatctgcgct atggtgtaga aaaataccag atggacagta agctatcagg
     5641 tatttatcct caggacaccc taaaagaggg tcaccttcta tttagaggct ttgatgatag
     5701 ctatgtatcc cctcattcac ggcacacgga gatttctaag gaagaggtct taaacaagac
     5761 taatctcgag attttatcag aaggacctca ggttggggtt tctattttgg ccagtcgtga
     5821 tttacgagaa atttatagtt ttggtcattt ggagtatgac cgtgatacct tggcaaaaga
     5881 gtattttcga gatcgtgatg caggtttcga cccacatatt ccagaaaatt actttaaaga
     5941 tgatgatgtt aatcaggtac cttgtctttg ttggtcttca tctgcagccc tctttttcag
     6001 taattgggta aaccatgcgg tctatcagga gacgcctttt gactggagaa agatagaaga
     6061 tgatgcatct gcatatgggt atttataaga ggaattatga catatttaga cgcttttaaa
     6121 tcaggtacct tggttttacc gagtgccctg ctcttgcatt ttaaggaact ctttccttct
     6181 agcgacgatt ttctggtttg gcaatttttc tatttgcaaa atacgacagg cttagaagaa
     6241 atgtcgccaa gccagattgc tgaaaggatt ggcaaggaaa tttcggatgt caaccagtcc
     6301 atttctaatc tgacggaaag gggactgctc cagtatcgta ctatcgaatt aaatggcgaa
     6361 attgaattgc tctttgatgc tagtttggcc ttggaacgtt tggatgacct gtttggagca
     6421 gttcattcaa gttcagacca gctaacacca caaaaccagc tcaaggattt ggtggaaacc
     6481 ttccagcagg agttgggacg attgttgacg ccttttgaga ttgaggattt gaccaagaca
     6541 ctaaaggaag atggaaccag tgctgacttg attaaggagg ctcttcgtga agctgttttg
     6601 aatggaaaac caaactggaa gtacattcag gcgattttga gaaactggcg ccatgaagga
     6661 atcaagagtg tggctcaaat tgaggccaag agagcagaaa gagaagcaag caatcctcag
     6721 ttgacacagg tatctgcaga tttcagaaat gccatggatc tctggaagga ttaatccatg
     6781 caagtaggct tgaaatccga gtaagatttg caagctgtgt ataattgtga tagaataaat
     6841 agaaaataaa ttgaaaaaag aggtatgtga aatgtcacgt aaaccattta tcgctggtaa
     6901 ctggaaaatg aacaaaaatc cagaagaagc taaagcattc gttgaagcag ttgcatcaaa
     6961 acttccttca tcagatcttg ttgaagcagg tatcgctgct ccagctcttg atttgacaac
     7021 tgttcttgct gttgcaaaag gctcaaacct taaagttgct gctcaaaact gctactttga
     7081 aaatgcaggt gctttcactg gtgaaactag cccacaagtt ttgaaagaaa tcggtactga
     7141 ctacgttgtt atcggtcact cagaacgccg tgactacttc catgaaactg acgaagatat
     7201 caacaaaaaa gcaaaagcaa tctttgcgaa cggtatgctt ccaatcatct gttgtggtga
     7261 atcacttgaa acttacgaag ctggtaaagc tgctgaattc gtaggtgctc aagtatctgc
     7321 tgcattgtct ggattgactg ctgaacaagt tgctgcctca gttatcgctt atgagccaat
     7381 ctgggctatc ggtactggta aatcagcttc acaagacgat gcacaaaaaa tgtgtaaagt
     7441 tgttcgtgac gttgtagctg ctgactttgg tcaagaagtc gcagacaaag ttcgtgttca
     7501 atacggtggt tctgttaaac ctgaaaatgt tgcttcatat atggcttgcc cagacgttga
     7561 cggtgccctt gtaggtggtg cgtcacttga agctgaaagc ttcttggctt tgcttgactt
     7621 tgtaaaataa tcagtaagta gcaaaagcta ggtggaacag cattcagatg tctgttacat
     7681 tttttatagg agaggaaaga ttgaaaataa aaattggatt agcaagtatc tgtttactag
     7741 gcttggcaac tagtcatgtc gctgcaaatg aaactgaagt agcaaaaact tcgcaggata
     7801 caacgacagc ttcaagtagt tcagagcaaa atcagtcttc taataaaacg caaacgagcg
     7861 cagaagtaca gactaatgct gctgcccact gggatgggga ttattatgta aaggatgatg
     7921 gttctaaagc tcaaagtgaa tggatttttg acaactacta taaggcttgg ttttatatta
     7981 attcagatgg tcgttactcg cagaatgaat ggcatggaaa ttactacctg aaatcaggtg
     8041 gatatatggc ccaaaacgag tggatctatg acagtaatta caagagttgg ttttatctca
     8101 agtcagatgg ggcttatgct catcaagaat ggcaattgat tggaaataag tggtactact
     8161 tcaagaagtg gggttacatg gctaaaagcc aatggcaagg aagttatttc ttgaatggtc
     8221 aaggagctat gatgcaaaat gaatggctct atgatccagc ctattctgct tatttttatc
     8281 taaaatccga tggaacttat gctaaccaag agtggcaaaa agtgggcggc aaatggtact
     8341 atctcaagaa gtggggctat atggctcgga atgagtggca aggcaactac tatttgactg
     8401 gaagtggtgc tatggcgact gacgaagtga ttatggatgg tgctcgctat atctttgcgg
     8461 cctctggtga gctcaaagaa aagaaagatt tgaatgtcgg ctgggttcac agagatggta
     8521 aacgctattt ctttaataat agagaagaac aagtgggaac cgaacatgct aagaaagtca
     8581 ttgatattag tgagcacaat ggtcgtatca atgattggaa aaaggttatt gatgagaacg
     8641 aagtggatgg tgtcattgtt cgtctaggtt atagcggtaa agaagacaag gaattggcgc
     8701 ataacattaa ggagttaaac cgtctgggaa ttccttatgg tgtctatctc tatacctatg
     8761 ctgaaaatga gaccgatgct gagagtgacg ctaaacagac cattgaactt ataaagaaat
     8821 acaatatgaa cctgtcttac cctatctatt atgatgttga gaattgggaa tatgtaaata
     8881 agagcaagag agctccaagt gatacaggca cttgggttaa aatcatcaac aagtacatgg
     8941 acacgatgaa gcaggcgggt tatcaaaatg tgtatgtcta tagctatcgt agtttattac
     9001 agacgcgttt aaaacaccca gatattttaa aacatgtaaa ctgggtagcg gcctatacga
     9061 atgctttaga atgggaaaac cctcattatt caggaaaaaa aggttggcaa tatacctctt
     9121 ctgaatacat gaaaggaatc caagggcgcg tagatgtcag cgtttggtat taagcgatga
     9181 tttgaaagag ggatgtgata gtagcaccct ctttttcttt gttttatgat agttcatcct
     9241 cgagtaaatt caagttcttg ctcggaaatg aagcttatat agtagattga atatagacaa
     9301 ataccttgtg attggtaaaa cattttagaa attcatttac ctttcctaat cgacttggtt
     9361 tcatcttatt tcaatctatt atagtattgg ggaatttctt caaaccacat cagcttggtc
     9421 agtcctacct gcgacctcaa aacttgtgct ttggtcaagc tgggtttagt ttcctagttt
     9481 gctgatggat ttccattgac tataagcatc caaccctctt ttttgtcttc taaagaattc
     9541 ttaaattatc agtctattgc aacttttctc atataagttc tttgtcttgc tattggtttt
     9601 ccttagtagt atactaaggt agtaatcatt aagaagtggt tacaaaaaat aatgaatgag
     9661 gtaaagaaaa tggtagaatt gaaaaaagaa gcagtaaaag acgtaacatc attgacaaaa
     9721 gcagcgccag tagcattggc aaaaacaaag gaagtcttga accaagctgt tgctgatttg
     9781 tatgtagctc acgttgcttt gcaccaagtg cactggtata tgcatggtcg tggtttcctt
     9841 gtatggcatc caaaaatgga tgagtacatg gaagctcttg acggtcaatt ggatgaaatc
     9901 agcgaacgct tgattacact cggtggaagc ccattctcta cattgacaga gttccttcaa
     9961 aatagtgaaa tcgaagaaga agctggtgaa taccgtaatg ttgaagaaag cttggaacgt
    10021 gttcttgtta tctaccgtta cttgtcagaa cttttccaaa aaggtttgga tgtcactgat
    10081 gaagaaggtg acgatgtgac aaacggtatc tttgcaggcg ctaaaactga aacagataaa
    10141 acaatttgga tgcttgcagc cgaacttgga caagcacctg gtttgtaaga aataaggaaa
    10201 catagataaa tctgtaggaa atttcttaca gattttttct attttgtaag ctattccaaa
    10261 ccagtctttt tttgagtttt ttgataaaat agtactatca gtgaaaagga tggaagcatg
    10321 actaagaaaa tcgtagctat ttgggcccag gatgaagagg gtgtgattgg taaggacaat
    10381 cgtctgcctt ggcatttgcc agcagaattg cagcacttta aagaaacaac tctgaatcat
    10441 gctatcttga tggggcgtgt gacctttgat gggatggggc gtcgcttgct tccaaaacgg
    10501 gaaaccctga ttttgacgcg taatccggaa gaaaagatag atggggttgc tacttttcag
    10561 gacgtccagt ctgttcttga ctggtatcag gctcaagaaa agaatctcta cattatcggt
    10621 gggaagcaaa tttttcaggc ttttgaacct taccttgatg aagtgattgt cactcacatt
    10681 catgctcggg tggaaggaga tacctatttc cctgaagaac ttgacttgtc tctttttgag
    10741 acagtttcaa gcaaatttta cgccaaagat gagaagaatc cttatgattt taccatccaa
    10801 taccgcaaga gaaaggaagt ctaatggaac ggagtttatt tggtctattc acggcttttc
    10861 tgtgtttcat ctgctttctg gcaggagcac aagcttttcg taaaaagcgt tacgggcttt
    10921 ctatcctcct ttggttaaat gcctttacca atctggtcaa tagtattcat gctttttaca
    10981 tgaccttatt ttagatagaa tgacagtata gaatggaagg aaatcatgtc tacaaataga
    11041 aaaaatgata tgatggttta ttgctcattt tgtggcaaaa accaagaaga agtacaaaaa
    11101 ataattgctg gcaacaatgc ttttatttgt aatgaatgcg tggagttagc tcaggaaatc
    11161 attcgagaag aattggttga ggaagtcttg gcagacttgt ctgaggtgcc aaaaccaatt
    11221 gaactcctcc atatcttgaa ccactatgta attggccaag atcgtgccaa gcgtgccttg
    11281 gcagtggcgg tttataacca ctacaaacgc atcaatttcc acgatacacg cgaagagtca
    11341 gaagatgtgg atttgcagaa gtcaaacatt ttgatgattg gcccaactgg ttcagggaaa
    11401 actttccttg cccagacctt ggctaagagc ttgaatgtac cttttgctat tgcggatgcg
    11461 acagctctga cggaggctgg ttatgtgggt gaggatgtgg aaaatatcct cctcaaactc
    11521 ttgcaggttg ctgactttaa catcgaacgt gcagagcgtg gcattatcta tgtggatgaa
    11581 attgacaaga ttgccaagaa gagtgagaat gtgtctatca cacgtgatgt ttctggtgaa
    11641 ggggtgcaac aagcccttct caagattatc gagggaactg ttgctagcgt accgcctcaa
    11701 ggtggacgca aacatccaca acaagagatg attcaagtgg atacaaaaaa tatcctcttc
    11761 atcgtgggtg gtgcttttga tggtattgaa gaaattgtca aacaacgtct gggtgaaaaa
    11821 gtcatcggat ttggtcaaaa taataaggcg attgacgaaa acagctcata tatgcaagaa
    11881 atcatcgctg aagacattca aaaatttggt attatccctg agttgattgg acgcttgcct
    11941 gtttttgcgg ctcttgagca attgaccgtt gatgacttgg ttcgcatctt gaaagagcca
    12001 agaaatgcct tggtgaaaca ataccaaact ttgctttctt atgatgatgt tgagttggaa
    12061 tttgacgacg aagcccttca agagattgct aataaagcaa tcgaacggaa gacaggggcg
    12121 cgtggacttc gctccattat cgaagaaacc atgctagatg ttatgtttga ggtgccgagt
    12181 caggaaaatg tgaaattggt tcgcatcact aaagaaactg tcgatggaac ggataaaccg
    12241 atcctagaaa cagcctagag gtgactatgg aacttaatac acacaatgct gaaatcttgc
    12301 tcagtgcagc taataagtcc cactatccgc aggatgaact gccagagatt gccctagcag
    12361 ggcgttcaaa tgttggtaaa tccagcttta tcaacactat gttgaaccgt aagaatctcg
    12421 ctcgtacatc aggaaaacct ggtaaaaccc agctcctgaa cttttttaac attgatgaca
    12481 agatgcgctt tgtggatgtg cctggttatg gctatgctcg tgtttctaaa aaggaacgtg
    12541 aaaagtgggg gtgcatgatt gaggagtact taacgactcg ggaaaatctc cgtgcggttg
    12601 tcagtctagt tgaccttcgt catgacccgt cagcagatga tgtgcagatg tacgaatttc
    12661 tcaagtatta tgagattcca gtcatcattg tggcgaccaa ggcggacaag attcctcgtg
    12721 gtaaatggaa caagcatgaa tcagcaatca aaaagaaatt aaactttgac ccaagtgacg
    12781 atttcattct cttttcatct gtcagcaagg cagggatgga tgaggcttgg gatgcaatct
    12841 tagaaaaatt gtgaggaaaa gaaaatggca aaaacaattc atacagataa ggccccaaag
    12901 gctatcggac cctatgttca aggaaaaatc gttggcaacc ttttgtttgc tagcggtcaa
    12961 gttcccctat cccctgaaac tggggaaatt gtaggagaga atatccaaga acagacagag
    13021 caagtcttga aaaacatcgg tgctattttg gcagaagcag gaacagactt tgaccatgtt
    13081 gtcaaaacaa cttgcttctt gagcgatatg aacgactttg ttccttttaa tgaggtttac
    13141 caaacggcct tcaaagagga attcccagct cgttcagctg tggaggtagc tcgtcttcct
    13201 cgtgatgtaa aagtcgaaat tgaagtcatc gcagagattg gataagctag ttgaagtttg
    13261 gtgttgccaa acttcttttg atataaggag aaaaagatga caaagaaaca acttcacttg
    13321 gtgattgtga cagggatgag tggcgcaggg aaaactgtag ccattcagtc cttcgaggat
    13381 ctaggttatt tcaccattga taatatgccg ccagctctct tgcctaagtt tttgcagctg
    13441 gttgaaatta aggaagataa tcctaagttg gctttggtag tggatatgcg tagccgttct
    13501 ttcttttcag agattcaagc tgttttggat gagttggaaa atcaagatgg tttggatttc
    13561 aaaatcctct ttttggatgc ggctgataag gaattggtcg ctcgttacaa ggaaaccaga
    13621 cggagtcacc cactagcagc agacggtcgt attttagatg gaatcaagtt ggaacgtgaa
    13681 ctcttggcac ctttgaaaaa tatgagccaa aatgtggtgg atacgactga actcactcca
    13741 cgtgaactgc gcaaaaccct tgcagagcag ttttcagacc aagaacaagc ccagtctttc
    13801 cgtatcgaag tcatgtcttt cggatttaag tatggaatcc cgattgatgc ggacttggtc
    13861 tttgatgtcc gtttcttgcc aaatccctat tatctaccag aactgagaaa ccaaacgggt
    13921 gtggatgaac ctgtttatga ttatgtcatg aaccatcctg agtcagaaga cttttatcaa
    13981 catttattgg ccttgattga gccgattctg ccaagttacc aaaaggaagg taagtccgtt
    14041 ttgaccattg ctatgggatg tacgggtgga caacaccgta gtgtggcatt tgctaaacgc
    14101 ttggcgcagg acttatccaa gaattggtct gttaatgaag ggcatcgcga caaagaccgc
    14161 agaaaggaaa cggtaaaccg ttcatgagaa aaccaaagat aacagtgatt ggtggaggga
    14221 ctggaattcc cgtcattcta aaaagtctgc gggaaaaaga tgtggaaatc gcagctatcg
    14281 tgacggtggc agatgatggt ggttcttcag gtgaactccg aaaaaatatg caacagttga
    14341 caccgccagg tgatcttcgt aatgtccttg tggccatgtc ggatatgcct aagttttatg
    14401 agaaggtctt tcagtatcgg ttctctgagg atgccggagc ctttgctagc catccattgg
    14461 gaaatctcat cattgctggc ttgtcagaaa tgcagggttc aacctataat gccatgcagt
    14521 tattgagcaa atttttccat acaacaggga aaatttatcc ttccagtgac catcctttga
    14581 cccttcatgc agtctttcag gatgggacag aagtggctgg agagagtcat attgtagacc
    14641 atcgaggcat aattgacaat gtctatgtga ccaatgccct aaacgatgat acgcctctgg
    14701 ccagccgtcg agtagtgcag gccatccttg aaagtgacat gattgtccta gggccaggtt
    14761 ccctctttac ctctattttg cccaatatcg tgattaagga aattgggcgg gctcttttgg
    14821 aaactaaggc agaaattgcc tatgtctgta atatcatgac ccaacgtggg gagacggaac
    14881 actttacaga tagcgaccac gtggaagtct tgcatcgtca ccttggtcgc ccttttatcg
    14941 acactgtctt ggtgaatatt gaaaaagtgc ctcaggaata catgaattcc aaccgttttg
    15001 atgaatactt agtgcaagtg gaacacgatt ttgtaggtct ttgtaagcaa gtttcgcgcg
    15061 tgatttcatc taacttcctt cgtctggaaa atggcggtgc cttccacgat ggagatttga
    15121 ttgtggacga gttgatgcgc attatacagg tgaaaaaatg agtttcacag tagcagtaaa
    15181 agaagaaatc ctgggccaac accatctgag ctggcatgaa ttatctgcca ttatcaaaat
    15241 gtctggtagc atcggtctct cgacttcggg cttgactttg tcagttgtga cagaaaatgc
    15301 caaactggcc cgtcacctct atgagtcctt tcttcatttc tatgaaatca aatctgaaat
    15361 tcgtcaccac caacgtagca atcttcgcaa gaatcgcgtc tataccgttt ttacagatga
    15421 aaaggtgcag gatttgttaa gtgatttgca cttggcagac tctttctttg gcctggaaac
    15481 aggtattgat gaggcgattt tatcggatga ggaagcaggt cgtgcctatc tctgtggcgc
    15541 tttcttggca aatgggagca ttcgtgaccc tgagtcaggc aagtaccagt tggaaatcag
    15601 ttctgtttat ctggaccacg cgcaaggaat tgcctccctt ctccaacagt ttttactgga
    15661 tgccaaggtg cttgagcgca agaagggggc tgtgacctat ctccagcgag cagaagacat
    15721 tatggacttc ttgatagtaa tcggagccat gcaggcacgt gatgattttg agcgggttaa
    15781 gattttgcga gaaacccgta acgacctcaa tcgggctaat aatgccgaga cagctaatat
    15841 cgctcggaca gtttctgcca gcatgaagac cattaacaat atcagtaaaa tcaaagatat
    15901 catgggctta gaaaatttgc cagtagattt gcaggaagtg gcgcaactga ggattcagca
    15961 cccagactac tctatccagc agttagcaga tagtctcagc acccctctga ccaaaagtgg
    16021 tgtcaatcac agactcagaa aaatcaataa gatagcggat gaattataac gatataaagc
    16081 aaccccttga attatcaata tcttcaaggg gttttgttgt gttatgaaat caaaaagggg
    16141 caatcaaggg gcagaattaa aaaatagtat ctaatttatt gaccagttta tcctccatat
    16201 cctcagtagt atgagaatag atttccaaag tcatttttgc atttgagtgc ccaactcgat
    16261 ccattattga ttttattggg aggccagact ctgctaaaaa cgaaatatga gaatgcctaa
    16321 aaatatggct agataagttt ttttctattt tggcctgttt tccatatttt tttaatatct
    16381 gtatgaagca agctattgtt gtaggttgat tccatttttc aaaacagaaa atataatcat
    16441 cgcttgacaa tggctggaaa cgttcgctaa gtcgtactat ttgtctttga atagcttcta
    16501 tgacattctc tgatactttg attgtccgta ttgaatttgt agtctttggt agcgtcttga
    16561 ttttgtttac tgaatcaaaa ttacctgtga tctcaatttt gttgttttcg aagtctatat
    16621 tcttcagttg taaggcagtt aactcaccat atctcatacc agttaatgtc agcacaagaa
    16681 ccatatcagc gtacttttgg tgatattctc gacgattaag gacatcgaca agtgctttta
    16741 tttcttgcat ggtgagaaag ttgttacgct ttttttccag ttcttctaaa gtctttggtt
    16801 tttgaggaat cgtagtataa tcgacctcgt tgttttcaat gtaagagtat tgaacagcgt
    16861 aattaaagat acctctgagc ctatgccgta cttttttagc tgtaatatat ccgttgcttt
    16921 caataatttt ttcaatagcc tcttgaagaa aacgcctgtc aagattagca agtatggtat
    16981 cggatggtat aacttccttc atcttcttat caactgattt acaattatgt tttgttgatt
    17041 cctttactgt ttgcgcccat gatttataaa aaaggttata gatttcttca aatgtaatgc
    17101 tttctacttg ttttgtgcta agttttttat ttatcttctc ttgcaacaag atagcagctt
    17161 gatttcttgc ctggggagtt ttcttctcca tggttactga aacttttttt aatttctcag
    17221 tatatggatc tttgtatcgc tcaaaaaatt tatatttgcc gtttggtaat tcttccatcc
    17281 acattgcgtt tacctcactt ttttgttaaa atgggtataa gaaaaagagc tttttaatgc
    17341 tttttttctt accactagcc tcacgctctc ggtctgcaaa cttctgagcg tggggctttt
    17401 ttgagttgtt tccaaaatgg aaacagttgg ttttaattta tacttttggt tcattacggt
    17461 gccaatcatt aggaaaacct aaagactggt tgattacatt gatgtctata gaaggcagct
    17521 ttttctctag tttgataact ttttttctaa gagtattcca caaaatgttg aatgctgctt
    17581 tactaataaa gcattgaagg ctaataattg ttgaatatac agtttttcta ctgtcatctc
    17641 ccatcaagat ctctttgtta tgaatcgttt cccaaaacgt actattagaa cggcatctga
    17701 agtttaataa gcgattattg tgagcgcatt tgtttcgtac ctcgttaata ttttttagaa
    17761 aagatatcaa ggtttctggt gggaaaacat cgttaaagtc aggtatgttt gtgcttataa
    17821 aacttactaa atcccgtgcg atttcatttt ggagtgaatt aggcaggttt tcaataatcg
    17881 tgcgtaaatc tccaaactct agataatcag ttagtaccca gattgggaca tctgaatgag
    17941 tatgtgcgta gtggtgaatt gaatttcctc tgtatcgctt gtttgtgttt atgattttgg
    18001 atagttttga tacaataaat cccacgtcta atattttatt atctgcataa gaattggtgt
    18061 ttaaataagc gtatttttga ctggggtaag cttcggcgaa tctgtgagca gtgattgact
    18121 tgatatggtg ttcagcttca agaatagctt gcaaaatggc tcgttttaca tctttgtcaa
    18181 atgtatagag acttgaaact tcgtcaaatg tgacgccgtc aatataagtg tcagtaccag
    18241 ggtgttgaaa aaacttactg tatccattga taatattgta gtaattgtta cttagcaggt
    18301 acttagctgc tttagattca tctgtaatgg ataaccctct gatttttagt gttgcgattt
    18361 gttcctcgat tgttttaaat ggcttcaaaa aaactccccc attctaattt agaatgaagg
    18421 agtttccccg tatcggtccc cgtagagatc ccgacgcttt ttctctaatg aattcattct
    18481 aaatgatttt tttaaaaaag tcaactgttt tttaatattt ttaaaaaata atttttttat
    18541 tcccctctat acaccccgac tactgcataa atcttgatgt gtgtgtcttc ggctggtggg
    18601 aagtctagga tgatgtcttc gtacttgtca ttgagtgaca ctaggcgtaa gcgtccgttt
    18661 tcggtatata tcttcttgaa gtaagaacgg tctccatatg cgataactgc taaatctccg
    18721 ttgtaggtag tcagtccttt gtctactaaa tagagaatgt ctccgtcttg gtagtcgggt
    18781 tgcatggagt ctccactgac cttggtcgca atatcgtggc gtggtggtcg ctcgtcaacc
    18841 tctatagtct ctctgtctgt atcgtcgtac ccaaatccat agttaaatcc agaagctgct
    18901 gccgtctcag atacaacctc aacttggtac aagctgataa cttccgatac ttcgtttatc
    18961 ttcgtttctt cttcgttttg gctctccaga agctcctcag aggtccgtag cacgattttt
    19021 tgattgggtg gggttaattg cactacctta tccattatct gctgtgtgag cgaatctgga
    19081 gcgtctggca gtgagttggt ggattcttct ttaaaagtag tatctatatc tgatttttta
    19141 acaccgaaat aatcagccag tttttggata acaccaaaag aaggagcgct tcttaacttc
    19201 atatagtctg tcatagtact tgctgtaatt ccaacttctt tagccaactc tttttgggtg
    19261 atgccacgtt gctttctaaa gtgtgtaata ttttcagcaa taatttgcat tcgttttttt
    19321 tcgtccattt acgattacct cgtatttttt ataattacat tatatatcat ttttgaatga
    19381 taaacaatca aaaatacgaa aaaatcctat ttttttgata aaaactattg acaatacgaa
    19441 aaaatcgtat tataattaaa tcaagcttaa ggaaaaggag gtaaggcaaa tgaacgaact
    19501 agaaagaaca gccctcaatg agatattgag gactgtgaca tatatagctg agaagttgga
    19561 tgaagtagat tctaagattt ctttgaacga ttcacaagct cttgagcatc aaggaaattg
    19621 agtttcattt ccatgtagtg aataactccg tgtaggtagt tctttaggtc tgtaaaacct
    19681 ttatcaggat tatttctata gtaatgacct tcgtcgttac cgatataagc agatgcaagc
    19741 gcaaatgttt taaggtcttc atccttgata tatttttcaa taacttgttt taatgacatt
    19801 ttaatgattt tatcttcatc atcaggattt gtaacaatgg agaaatcttt aacaaagaac
    19861 tcaagcgcct tacggtatcc aatacctgca atgtggtcta gttgttcgtg ttcagctttc
    19921 agtgcttgga catagatttg cttaccaatt ggagaaacta tctctacatc gtcagatata
    19981 ggtatatcgc tcggaagatt agggattact ttgatatgtt caatttcgta tttttcggta
    20041 tagtcattga ttaaaaatct tgtagctata aactcctctg tccaaaagtg cttacaacct
    20101 aagcatctac atgttaatac taagcttgtt ttattttctc caagagaaaa ataagaagag
    20161 ttcacaagat ctggattggt tggtttttta caatttgggc aaatgtcttc aacggttaca
    20221 ggcctagaaa cagaagaatt tactttcact cgaaatatca taagatttct ccaatcgttt
    20281 tattttgatt ataccatatt tgaaaggggg tgaggaaatg agaccaagac gatatccgta
    20341 tagtgggaaa aaagagtcca ccttcgtaaa ggcagaccct gagttaatgt tgaatatcaa
    20401 taagattgat gttggaaata tacaagcgaa aaatatattt ggaaaaattt aaggagtagg
    20461 aggatggatg aaagaaaata tagaacatct tcatgaacgc ataaagcatt ttcagtcatt
    20521 gattgcttat atgtctgagc atgagaaaaa gtattattta gaaaaagatt ggttcgataa
    20581 cccaacccta atttctatag aagacgcaaa aaaagaagta gaactacttt aacagaaagg
    20641 aggtaggaac gtgcagtgga ctttagaagc tatgagaatc aacaaaggac ttactcaagc
    20701 agagttggca gaaaaatttg aagtttcaag tcaaacaatt gctagattag aaaaagatag
    20761 ctctgatatc ggttatcagc tattgaaaaa atacatgttt tttttcaatg tgaaattcga
    20821 tgatattttt ttagggaaaa aatacgaaaa tttcgtaaat aactagaaac aaaaaaataa
    20881 gaaggaggaa cacatagatg gaaagcgttc ttgaaagctt gaaacaagaa aaagaccacc
    20941 tcgaaaaaat cattaaggta gttacctctg gtggtaaatt tctgagattg ccgtatcaaa
    21001 aaaagtcacg ctcgattagt gagaatctga aattgatttc tcaaaatctt gataaattga
    21061 gcgagcaagt tcaacaaacc acgaatcagc attcatgatt tcaagatgac gaaagaaacc
    21121 tgttttgatt tccagtttga tatcatgtta cagcgactcg ataaagcgat tagtgattaa
    21181 atttttgaga tgtaagtttt tttcatgtca aactttttca tgtcaaattt tttacactaa
    21241 taaatattaa ctaacaacaa gtattaaaag acaaccagtc ctacttctct aaataaaaga
    21301 gagggtagaa aaaataaata caaaggaggt gaggaaatga gaccaagacg atatccgtat
    21361 agtgggaaaa aagagtccac ctttgtaaag gcagaccctg agttagttga aaaactttta
    21421 agaaacacta gttttcttga gcgtttacaa aaaaagccta tcaattttca gatagactca
    21481 gaagaattta agcgtcttag ctatgaagcc attcatgata cttcttaagt aactcaatag
    21541 tagttattac agaagtcaaa ccactgacct tccccagttg caatccgtct gtatggtcaa
    21601 tctgtttagt agcttcatta gctttagcag agatagcttg catatcttca gctgttaaag
    21661 attctcgaaa atctttaaag gatttcataa aaactcctcc tttctattgg aattttgact
    21721 aaaacggtga gaggtcctag tcgagattat tatagcaatt taggaggata ttacatcggt
    21781 cttgaggctg atttttggag gcaatattgg aagataaaat catagaactt gctgattact
    21841 tcatcagcga atctacaacg tacagagaag caaaaatagc gtgtgagaag ctattgaaac
    21901 aagtcagcca cgagattgaa ctcagggcga tggaaagtag gacagtatga aagaagcagt
    21961 aaaggaattt ctaaaattca ggagccgatt tacaaaaata gaatggtttg aaatcaacca
    22021 agctgtcgaa gctcgtttaa atcaaaaagc cgaccagttg aaactggacg acgtagattt
    22081 agaaatcatt tctagcagac tagaaaaagt tatctagaaa cgatttgaat gaacattgga
    22141 tggatacgat agtcagcgcc acgatagtga atgtagatat aatcctgatg gtacatcgag
    22201 tttgcttcag gtttagaaat tggtgagtag agttctgcat tttcttccca ccaaatgtaa
    22261 ggactagcca tatttggtcc cattacacaa tcgtcgtcgg ctgataggtt cacccaattt
    22321 ccgcaaagac atgcgtgaat ttcagtcata atattacctc ctttctggtt tcattatagc
    22381 agaaaaggag atagcaaaaa agcacctgac ggaaatcagg cgcatactta aatattcaac
    22441 atgattataa cacgaaagga gcaaaaatgg aagcagttga aattgtaaga attaaagatg
    22501 tgattattga aaaagtctct gctaatgatg aagagttaaa acgtatcttt ggatgttcaa
    22561 aacgacaagc aggagagcga agaagagaaa tgcaaaaact ccctagtcag caaaaacatc
    22621 ttttggatag tggacaactt gtaacgatta aaggtttcta tgaatacttg caatatcgtg
    22681 gaactaaagc ttggaaaaaa gaaatggaaa caagcaagaa aatgaggtca gcaggatgaa
    22741 cctactatca agaatcaaaa actatttttc ggaagaggtc aaagaaacta atctcgactg
    22801 gaaagaggtc gctttagacc tcaatcaatc actaattgaa acacaggaaa aacttcaaga
    22861 agcgaatcaa gaaatcgcag acttgaagaa aatcgtagca atctataaag aaaaggagaa
    22921 agaaaaacga tggaatatat ttacctggta acaatcgtag gaattggact atggtcgcta
    22981 gtaaataaac tagatgacca cgctgaaatg aaacaaaaag agcgccagct gatggcaaac
    23041 aatgtcgcac ggatgaatct gagaaattca gataagcaat ttacttatga tgtagaaccg
    23101 cctgaagggt tgaaataagg aggagaaaca tgactcaagc tgaacgaatt agggaatatt
    23161 atagagagca ccctgctgcc tcatatgatg aagtggctga ggtcgttggt acaacaaata
    23221 gtaatgtgag agcgaacctg gccaaagaca tcaaggcagg cagatgcgtt cgcttggaag
    23281 ataagtcata cgattactcg ccttactata accatacaca ggcactcact gagttggttg
    23341 actggaagaa tgacaacaga cgtgagtggg tggatatgct gacaagagca gcagagaaag
    23401 aaacggatag caacgttatg cgtttgttaa tcaaagaagc aaataaattg atgaaagagg
    23461 tgactaagta gatggtacga aataaaatag gtgatttaac taacacgctc ttcgctcaat
    23521 tagagactct ggatgatagg gatcttacag cagatgaatt aaaagtagaa ttacagcgct
    23581 cgaaacaaat ggtcgcaatc tcaggtcaaa tcttacaagc aggtcaattg gcgctagatg
    23641 ctgaaaaatt caaagacaag gtaggtgaag tcaatgcccc gatcgctttg ctggaaggat
    23701 gagtacacgg agtacatgca tgaaatatgc cctggtcgtt taactcctga agtaaccagg
    23761 ttgctgaatg aaaaatttgg tacgaattat aacaagagtc aaatcggtgg cgtacgcaaa
    23821 cgtctagggt tagcagttgg aaaagtctat caaggtcgat tgctgacaaa ggagcaacat
    23881 gattatcttg tattgatcca aaaaaataag atttctcgta atgtcgcaaa tgaaatgaac
    23941 caaaaatttg gcttatcgct aactgagaaa cagattaaga gttatcggag aaataataat
    24001 ctacatagtg gtttgacagg aagattcgag aaaggtcaga ctcctcacaa taaggggaag
    24061 aagtacccca atatgccaaa aaacggcggg cagttcaaaa aaggtaatcg acctccgaat
    24121 tatgtacctg tcggtactat caactacaca acaaacggtt atccaaaaga aaagattgga
    24181 gaacctaatc aatgggtttt gaaacaccgc aaggtttggg aggaccatca cgggctgata
    24241 ccaaaagggt actcaatcgt ttttctggac ggtgataaaa caaactatga tatttcaaat
    24301 ctggcatgtt tatctaagaa cgaaattgct agaatgaatc aaaatcattt attcacgtcc
    24361 aacgctgatt tgactaaatc aggtattgga ctaacaaaac ttacaaataa aatcagagag
    24421 gtagaaaaaa atggctagtt tatacgaact aacaggtcag ttcctgacaa tttaccaatt
    24481 ggatatcgat gacgaaacaa aagcagacac gcttgaggcc atcgattggc aagaacaatt
    24541 tgaacagaaa gcagaaggat atgcccatgt tatcaagaat ctagaagccg acgtggcaat
    24601 gtacaaggct gaggaagaga gcttcaaagc caagaaacag gtggcacaga aaaagctgga
    24661 ttatgtcaag gataacatta tggcagctat gaatgtcacg gggcaaaccg aagttaagag
    24721 tggtgccctg attataaaaa ttgctaagaa tccagaatca gtcaaggtca acgaagacga
    24781 ccttccgaaa aaatatttta caaaaaaagt gacgcttgcg ccggacaaaa aaacactcaa
    24841 agagttgctt aaatctggca agaaagtcaa aggtgcggag cttgtccgga cagaaaagtt
    24901 ggtgattaag taatggaatt gatgaataaa acacgagtaa cagattcact agcagttgtg
    24961 attggaccag aatcgattga agtacttgtt actgaaggtt ttctatttga tgttgcgatt
    25021 cgttttgtaa aagtagacga aacaaatctt gatcaaggaa atgaaaagcc agtattcact
    25081 ccggaataca agctggtcac agttgctaaa tacaaggaaa aacctatctt tgaatcggag
    25141 gaagatattc gaaaatttga gaagcaagca aaagaagtta aatcgctatt tgcctttgca
    25201 aaggtaaata aacaaaattg gtttaacact gccctttatc caggagtgct gactgagaaa
    25261 gttggtgttt gatgaaaatt ttagctattg atccaagcag taataaaatt gaaaccagca
    25321 caacaggagt tgtcttgttg gataatgcaa gattagttga tagctgggtt gtctcttatg
    25381 gtatgagagg tttcgctgat tggtttcacg aaatcggaac aaatcttgaa ttcgatgtag
    25441 ttattgttga agaatttaag gcgagggata acgacaagtc gaaagataat agcgtggcag
    25501 aaaccatcgc ctatatccaa ctttgctatc caggtgccat tcttcaattc aatgcaggtt
    25561 acaagtcgga tattccaaac gatcttttga aaatcttaga cctttggaaa tttgaaaaaa
    25621 gtcatcatca agatattcga gcagcagcaa gacttggatt attttgggca atgagaaatg
    25681 atattgaaga agtggttcat gatatcggaa aggtggtgag tgagtatcac aataacgcta
    25741 agaaagtggc aagctgaagc gattaaaaga agtgaacatt tatctaatgg aatcttttta
    25801 gaggctcttg ggggcagagg caaaactatc tgtgcacttg ctattgcaaa acataaaaaa
    25861 gctaaaaaaa tcatcatcac aaacaatcga ctagctattc tgaatggttg gatagatgca
    25921 gtcaagttta tgaattttga taaaggtgtt gagattatca ttcagacaga tagatatctt
    25981 caaaatcaag tcaaaaaggg gcataaatta gattgtgatg tgctgatagt agacgaatgg
    26041 cagaatatgt cttctgacaa acaagtggcc ttatatcgca aaataaagcg aaaatacacg
    26101 ataggtcttt cagcgacacc aattcggaaa aaaggacaaa atttctatcc gcttgaaaaa
    26161 acggtatttg gttgggcaac cccaaataat aaatttgact ggcaaaagac tcatggaaaa
    26221 atggtctatg atccatttag ctattcaaaa gagaagtggg aagattttca aaattatgaa
    26281 agttatatct cgagcttgcc taatttcttc cgctgggaag acattgaaaa gattgagaat
    26341 gccactgaaa ataacggttt tgaaaccaag ttctacccag tcacagttaa agctggaaac
    26401 cctgagaaat tagctgagtt taggcagctt aacttggtca ctgttggaga caagacggct
    26461 atggccaaac agtcctttgg tcgcaagacc tttgaacggt acctaaatca aactggtgtg
    26521 atcgttgatt ttccaaagtt gaaaccagtt aacgctgata cccctctcat gctcaaattg
    26581 gacggattga ttgaaagagc accacacgat atgttgattg tcagtaaatc taagcagatt
    26641 gtcaacgtca ttagcgagcg ccatcctgaa attggaatct ggacgggcga tattcaagaa
    26701 ggactttata agaaattcgt ggttgctact agtcaagtgt taggtgtcgg agtagacggc
    26761 ttgcaacaca aataccaaac tattgtcgta ttggatccag tagaagaagg ttctggagaa
    26821 tatgatgatt atcgacaatt gctctggcgt ataacaggaa gtcgtcagca gcatgatgta
    26881 aatgtaattg aattttatta taaagaaagt taaaaaaaag aggaaaacaa aatgaataaa
    26941 acaactgaaa tgatcgtatt tcgtagccgt aaaactggag aatttcttaa ttcttacaag
    27001 gacagaagtt ctttagcatt tgcagctgac ttttgcagct tggaatattg tttgaagctt
    27061 cctcgtaaaa aatacgaaga caacaaaaag acttacaagg ctcttgctgc agcttttgac
    27121 tgtgaaattg tcgcagttga agcggaatac aaattgacct atccgaatgg atcagaagtt
    27181 gaacctatca agcgtgaccg ttcatcaatt gaggacatga ttaaggatat tattggaggg
    27241 gttctctaat ggcatttaca cttccagtaa ataaaccaca agttccagtg gatactccaa
    27301 gaaatttttt catctacggt gaaaccatga gcggaaagtc ttatcttgca aatgaattcc
    27361 caaatccaat cgttttgaac acagacggga atgcagaagc taacactgtt ccaagcattc
    27421 agctgatcaa tgaaaaagat gacaagggac gaattaccaa ttcagtaatt aagcagcttg
    27481 gagatatctt gcttgctctc cagacacaga agcactctta tgaaacagtc gttattgatg
    27541 taattgacga tgttattgaa atgattaaga ttgcagtttg tgatgaatta accccagttg
    27601 gtaaacctcg cttgaaatcc ttgtcggaaa ttccatacgg caaaggatac gacttcttta
    27661 accaagctat cacagaatta gtcattgacc tcaaagcatt gccaatgaat gttatttaca
    27721 tcagccgtca ggtatctgaa tatgatgaca atggcaatgc caccaaagac aagccaagct
    27781 tgaaagataa gtatgtcaat cttatcaatg gaaactctga tttgatgatc cacactgaaa
    27841 aactcggcaa caactacaac cgtgaggttg accgcaagcg taagacctat tatgcggacc
    27901 aggttgatga caaggccatc ttgaaaatct tggcaactat ccgtggggct gttgagcctg
    27961 caaagggcaa gctagcccct aaaaaagaag cagctaagac aactaaacca gctaagaccg
    28021 aaaaaacaaa agaggcacct aagaaagaag ttgactctga tgatgaacta ttttaagaaa
    28081 taaaggagaa tacacatgag cttactagat atcgcaaaat caatcaaaaa agagggcttt
    28141 gacccacgca aagacagcgc caacggtcct gcaccaatcc cagctggtac ttatccagta
    28201 gtcctgaaga aagcaacctt caacgtatcg gacaaaggct gggaaagcct tggttatcaa
    28261 tttgaaatcc gtggcggtga ttacagtgga cgctctgaat ttgcaacatt tggcacactg
    28321 actgaatgga acggtaagaa ccttgactgg gcagttgaac gcactatgaa attctttatc
    28381 aaagccttgg tccttgctgg cgacagtatg caaggaaatg aagaagacgg taaagccttg
    28441 gaagaggctc taaaacgtaa ggcagttggc tcttactaca accttgttat ctctgtgact
    28501 aaggggaaag atggccgtga gttccgaaac tatgaccttg aagaagaagc acaaccgctg
    28561 actgaagctg atattgatga cgatgacctc cctttttaag aaataacaag ttctgggtca
    28621 ttgatgaaac tgatgaggaa tttggtcctt tcacgacagt agaagaggct tatacagcta
    28681 tgctaacata cttggatatg actgaagatg aatatcaatc aaattatatg gcccaagaac
    28741 ttgtttatat ttacaaagag gagaagtaat catgccgtcg atgaaagaat acgcattaca
    28801 gtatcaaaag ttagggttct cagtcattcc aatcaatcct aaaaacaaga tgcctttgat
    28861 taattttgct gataagccag ccatgactcc atctgagatt gaaaactttt gggacggcta
    28921 ccctaatgca aacattgccc taaagactac caacttcttt gtcattgata ttgacaaaca
    28981 cggcaaatcg aacggttttg aatcgctaaa aaaatggaaa catctaaatt taatcgaacc
    29041 gacactgcaa gctaagacgg ctagtggcgg taaacatcta ttctacttca aacgagaaga
    29101 tgagccgatc actcagatga ttggattctt gcctggtgtt gatattaagg ctcacgaaaa
    29161 taattatgtg ttagtcgcac cctctgccac agataaaggg cagtatgagt gggatctgga
    29221 aaagtctaag gaaggtggca cgatggtcac tccttcaaaa tatttaatcc agtctataaa
    29281 aaaacagtat ggcgaaactc acggttataa gtatgatggt aaggacggtc ttagggattt
    29341 agttagacgt tcacatacta gagaccgaac acagactaca gatctctttg aaaccatcgc
    29401 ccttggtttt ggtgatgaag gtggacgaaa tgacaaacta gcaaaattcg taggtggtct
    29461 cttatatcgt gcggtcgacg atggtgtagt tgttcaactt gcaagattag caaatgcaaa
    29521 tagtccaaac cctttgcctg aaaaggaaat gatgcgtact attgaaagta tgattaaaaa
    29581 agataggagg tgattgtgat tggtaatgta gtaagtattg actcacaacc taagatgata
    29641 acgactgcca agggagacat caaggccaac agtccaagta atgtgttgat gtctttcaaa
    29701 gctgatgatc agttgagtat ttacctaaag cacaacgatt tttcccaaga gcatgaactc
    29761 cttaaagata tcaagatcgg caacactctt tttaaaaaag gtgagctccc ttctaacttt
    29821 gattcagtcg taaaagttta ctttgaaagt gtgttaggtg ttgctttctc aaaccaagcg
    29881 atgcttgatg gcatggagac tttcttttca gaaagatcat acaatccagt tattgagtat
    29941 atggagagag caactgaaaa gtgggacggc agaaaccgga ttgaccgcat gcttcaagta
    30001 tatctcggcg ctgaagatat ccctttagtt tctaaaatcg ctcaaatgtg gctagttggt
    30061 gcagttgcta aagtttatga tccatacgtt aagtttgact atgttctgga cctggtcggt
    30121 ggacaaggag ttgggaaaac gtccctcctt caaaaattgg gtggcgaatg gtatacggat
    30181 gccgtaacag atttctctaa taaagataat tacgacatta tgttaaagag tctaatcgtc
    30241 aacgatgatg aaatggtggc cagtaatcgg atgagctttg cagaaactaa ggcctttatt
    30301 tctaaaacta gcctacgtta tcgtaaacca tacatgaaac gaacagaaga atttgccaag
    30361 aacttcatct tagccaggac tactaatcaa aaagaatacc tcaaggacaa aaccggtgaa
    30421 cgtcgttttc taccagttat ggcagatagt aaacggcaaa aaaaacatcc aatggaaatc
    30481 gagccagaga caattgaaca aatctggggc gaagccgtta caatctatcg tgctggtgct
    30541 gatttgatgt ttgatgaaaa tacagaggat gaactgaata tctaccgtga acagttcatg
    30601 tatcgtgatg aagttgaatt acaagtgctt gaatatcttg atatgcccgt ccctgaaaat
    30661 tggcaaaact ggtctattca gcaacaacat caatacacaa gtaaatattt cgataatagt
    30721 agcgactttg atcctggaag caaaaaacta gataaggtct caactcgtga aatgatgtac
    30781 aacttattta tgagaaattc gaatgacagg aagctgtcaa cgaagattaa catgatcatg
    30841 gataatcatc ctgattggaa aaaaagtgtt ttccgggcag gaggtaaaag tacaaaaggg
    30901 ttcgtaagag tgaaagattc ggaaaaaaac taatcggtag caattaaaaa attatcggta
    30961 gtcatcggta gcagttgagg gggagatcgg tagcattcta ccgataaaat aggacatcgg
    31021 tagcacatcg gtagcagtct aaccccttga tattactgac ttttatttaa tatttatata
    31081 taatgctact cttctaccta tatttttaaa aaaagtatat aaaataatag taataataaa
    31141 gaaagcctat aaaataggga ttcttgaaaa aaacttttta ctttttagaa tttatcggta
    31201 gcacggtagc agtttagaaa aaagaggtaa aaatgtcata cacagtaaca ttattttttg
    31261 acaacatggt agacgaaact cactttttta agaaagagag tgatgctgcc aaatgcaagg
    31321 cgcagttaga aagcaagtat cgagggaatc gaatgtataa agttaagcag gagaaattgg
    31381 aagaatgaat aagcaggaac tgattaaacg tatcgaggat ttgccttata cagaggggcc
    31441 tatcgcagat acaatcgaaa ttaatagaaa ttggatattg aaatcaattg aacagctagc
    31501 cgaatccgaa ataggtcacg cagatgaagc tccacgctac gtaaagaaca tactagcacg
    31561 attgcgagaa ttgccattgc atgatagaga ggtttggtta aaggctatca tgagcgaatt
    31621 tgaacaggat tttagccatg caaaatggcg agagggctac gagcaaggta aaattgaggg
    31681 tatggttgaa cgtgaaaaag tcatagttcc gcagtgtgtg gcggaatata tagaatttaa
    31741 aaagaaaaac aattttcatg tttacggtgc aatgagagta attgaagatc attatgataa
    31801 gaaagttcct gattggtttt acgaaaataa catcgaaaaa ttctgtcttg cttggcttga
    31861 cggctacgag gttgaaaaag agaagcggta ttttgttaag attaaaggga atattaaaga
    31921 aaatatgttg gtttatggag aacttttgaa aaggtatttc tttacaaaaa gctttagttt
    31981 agacgatgtt atatattccc acactcgtaa agaactagaa gacgcaaact tcggctgggt
    32041 gtttgattgt ccagggattg agattgagga ggtggagtga tgagccttac gctaaatagc
    32101 acaattggag acttagtttt ggcaatcgga gaaattatcg ttggttctga tggtaaaacc
    32161 actacagcga tactggagat acctgatcaa agcttttact tagagattga gcttaaattg
    32221 aaggaggagg tcataaattg aaacgattca tagctatctg gattctgcta tctgctggat
    32281 tgaatatctg gcagagtatc tacattaaaa agttagaaga aaagcgccct attgtcgtct
    32341 ataaagctga taacgcaggc gctgagatat tcggtaaagt cgtcgagaaa ggacggcatg
    32401 gcaagctata cacgcttacc attcgtgact acggggtgtt cgtggttacg aaggacgtgt
    32461 atgagaaagt gaaagtaggg gatgaggtgt tactctaatg gatgatattt tacaagcttt
    32521 agcaaaaatg ctaaatatga ctgttgatga agtaagttct ttgcttacaa catttaaagg
    32581 gaatgcacca cagatttatg aaatgttcgt taaagaaaag atgttttatg atctcttcag
    32641 tctttttcaa atcatgtcaa ttgtaatatt tagtatttct gcagtagttt tagcagtttt
    32701 aactctcata tattttacat acgatggtgg ttttgtttat tcctatgata tacgtacagg
    32761 aaaaaccgag gaagaaatta aattagaacg cattgaacgg aaaagaaagg acttaaaaat
    32821 accactaaaa attagttgca tttcatcaag cgcaagtttg ataacattag ttattgcaat
    32881 tgttttaaaa gcaactcttg cacctaatta tatattcatc gtgaatgaga ttttaccaaa
    32941 attaacgaag agataggagt tatcatgaac gcactagaaa aagtcgaaca atggtttatc
    33001 gaccgtgaaa tcaaagaccg aaaaggtcgc tggattgatg gctcgtttgt caaagaggag
    33061 gatttggcat gataccgaaa tttagagtgt gggtaaaaat aggaaaacgt atggtttttt
    33121 cagatgacat tcttgctatt gactacgaaa acaaagaaat agtgacacaa caagtttatt
    33181 ttgagaatgg tttaccagac gatagagata tctattgtta tgattttgac gaaatcgaac
    33241 tcatgcaatc aacaggactc aaagacaaga acggcaagga aatctttgaa ggcgatattg
    33301 tacgaactac tagatttttg ggtagagctg acgaaattgg cggtttctat gagtatgaca
    33361 aggaatttat agggattgtt aagcagcttg agggttcttg ggtaattgat acgggcagtg
    33421 acgcagtatg tttatggact gaaattgaag aaaatgaaat catcggcaac atctatgaaa
    33481 ataaggagtt tggaggacgc aaatgagacc ttgtaaatat ccatattcag gaagaagaaa
    33541 aaaacaagaa acgccgtcgc caatattttc tgcacgacca atttttgacg aagttccaat
    33601 tgtagaagaa gttaaggttg agttcggagt tgaagctagt atggggcgca tatatccaga
    33661 aacgttaata catttagata tttctggata cggaaataga gtgcattcag tacatcgctt
    33721 ccccggtatt ttactgagtg ttggtgagtc aatccaacta aagatgcttt tctataaaag
    33781 acttagaaat tttactacag atcgtttctt gacgtttaga gaatctgatt ggaagttctt
    33841 tatccgggac ctggtcaacg aatttgtgcg ataaaaaagc caagacactc tctgtctcgg
    33901 ctaaattcct aataagacta ttatatcaca aaggagacag agagtgaaca aggctaaaga
    33961 actattgaaa gagttgcaga atctggacat ggacattcaa agccgtatag atgaaattaa
    34021 cgagcttgag gcaggtttgc tctcaagccc caagtggatt gacgtcaaag tccaaggtgg
    34081 tcaagctaga aaagttgatg atgtctatac tcagcttgtc gtgatgaaag aggccataga
    34141 acaggatact aaagaggtta tcaacagaaa gcttgagctt ggtaggttga ttaacaagct
    34201 gaaaaatcca aagagcaggt ctattctcag ggtgacttac attactaaga tgtatgttga
    34261 tgatatttgt gacaaaatgg aaatcagcag aacaactttc tacacttggc ggaatatggc
    34321 tatctctgaa ctgaatgagg ttttggagag aatggaacta aattgaactt tacaaaaccg
    34381 tacgggaaaa aatgatactt gttagcacag ttttgtaatt ctgataaaat ggtagtatca
    34441 agaattgaaa agagaggtct cagaattggt agatggttac ctgtaatgtc agggggctgt
    34501 aatggccttg gaggttcaag tcctcccctc tcctttgagt gtttgtgtcc cagaatgagt
    34561 taaatcttct gggtggggat tcacatatca ctcattaact taaaaatggt tgcggaagcg
    34621 actggacctc gcatgattgc gtagctaatt atattccgga taagttataa gctagagggt
    34681 ttgattccct cagaggtttt aaagactaca aaaaataaaa aagaagtcaa aatttaatac
    34741 gcacgcaagg tagtagtcgc cttgcaagaa ggtcgcacat cgtgtggctt tttttgatta
    34801 ttcgaagggt ggtgatggaa aattgagtgg attgagaata aaacaaaaga gatttgcaga
    34861 tgagtacatc atctcaggta atgcgacgga agcctataag aaagcaggtt atcgtgtttc
    34921 tagtgataga gtggcaggcg ttgaaggaca taagttacta aagaatccta agattaaaag
    34981 ttatatagat gaacggttga aacagcttga ttctgaaaaa atcgcagacc agcaagaagt
    35041 ccttagttat ctaacctcgg taatgcgagg agagacacaa gaacagactt tgataagcat
    35101 cggagaattg ggtcaaacga ttacggatat taatgttgga gcaaaagaca gaatcaaggc
    35161 agccgaacta ttaggaaaac gtcataggct ttggacagac aaagtagagg cagacgtttc
    35221 tgggacggtg gtgtttgcaa atgagtcaga cataccagat taaacaaagt gatattgtaa
    35281 tcgacctacc taagacagta ggagctggat acggacagtt ctggcgctca agaaatcttt
    35341 atcgtgttgt aaaaggttcc cgtggttcga agaagtccaa gacaaccgct ttaaactatg
    35401 ttgtccgtct tttgaaatat tcctgggcca acttgcttgt tattcgtaga tactcgaata
    35461 ccaacaagca atcaacttat acggatttta aatgggcgtg taatgtgttg ggtgtgactc
    35521 atttgtttaa atttaacgag tctttgcctg aaataaccat aaaagcgact ggtcaaaaaa
    35581 tcctattccg tggtttggat gatgaactca aaatcacatc tatcacggtc gatgtcggca
    35641 gtctttgttg ggcatggttc gaggaagcat atcaaattga gactgaagac aagttcagca
    35701 cggttgttga gtctatccgt ggtagcttag atgtacctga tttctttaaa caaatcacag
    35761 tcacatttaa cccgtggaat gagaggcatt ggctcaagcg tgtattcttc gatgaagaga
    35821 cgagacgggc tgacacattc gctactacaa ccacttacaa atgcaatgag tggcttgatg
    35881 aagtcgatat caaacgctat gaggatttgt atcatacgaa ccccagacgt gctagaatcg
    35941 tttgtgatgg tgaatgggga gttgctgaag gtttaatcta tgagaacgtg accgtcaagg
    36001 atttcgataa ggatgaattg ctacgagatt cagctaataa gttatgtatc ggtcttgact
    36061 ttggttttac tcatgatcca actgctttgt gttgttcgtt gataaatgac acgacgaaag
    36121 agatttatgt ctttgatgag gcgtataaag tcggattgat aaccaaagaa gttgcgaaga
    36181 tgataaagga caaaggttat catcgctcac aaatcattgc tgatagcgct gaattacgac
    36241 tgattgaaga gctcaggtca gaacatggca tatctagaat aaaagagagt cggaaaggta
    36301 aggatagtat tatggcaggt gtatccaaat tgcaaggata cgttatttat gtgcatccag
    36361 attgtaaaaa catcatggat gaattttata gttactgcta ccagcgagat aaagaaggca
    36421 actggttgaa taaaccagag gataaaaaca accacttgat ggacgctttg cgttacagcc
    36481 ttcaatgtat cgaaggtggg aaagcaaccg tccgcagacg ttctgattat ggtctataga
    36541 gaggaaagac atgtaccaat atttaaccta tccacgggat ggatatgatg agggttcttt
    36601 gaagaaagac ctgatttaca aattgataac gatacataac actgaaagtt cacatttgaa
    36661 gaagcttaaa agctactatt tgggtgagca tgctatctta gaacacacga gacgcaacgt
    36721 gaacgcacct aattacaaga cggtagccaa tcatgccaag gatatcgcag acacggctac
    36781 gggctatttt atgggcaatc ctatcaagta taacaatact gctgacggtg atatcgatga
    36841 actacttaca gcctttgatg gtgctgagat tgaccaagta gatgctcaga atgctttgaa
    36901 catggctatc tatggtcgtg cttacgagta catctatgct aaagagggta tggctgagtt
    36961 ggattcaact agtattgatc cggagaatac tttcatggtc tacgatgata gtattgagcg
    37021 gaagcctttg tttgcggtct attactatga agtaaaagac gatacgaaag acactaccaa
    37081 gcaccaggct gaggtcttta ccgaaaatct gcactatcac atggtgctga gaagtacaga
    37141 ttcaggaaca actcagagcg aggaggcaac acctcacaac cttggtcaaa tcccaattat
    37201 cgaatatcgc aacaatcact ttgcaattgg tgactatgag caacaaatta gcttgataga
    37261 cgcttataat tccttgatgg ggaatcgtgt caatgataag gaacaggctg tagagtctat
    37321 acttgtcttg tatggcacgc agttagcaga cactccagaa gacgctaagg tagcaatgaa
    37381 gattctttct gaagaaggtc ttttggaatt gccgggcgat agtgcaaggg ctgagttctt
    37441 gaagaatacg ctggacgaaa gtgctactga aatcttgcgt acagctctta aagaggacat
    37501 ctacacattt agccatgtgc ctaatttgac tgatgagaat ttcgcaggga atacatcagg
    37561 tgtagccatg gaatttaagc tgatgggcct tgaaatgatt actaagacca aggaagcgaa
    37621 ctataagcga ggattgcgtc agcgtattgc gatttttgct cattacttag gcatgaagca
    37681 gattgcttta gagtctcatt caatcgttcc acaattcagt cgtggtttgc ctaagaactt
    37741 gttagaaatc tctcagatcg tgaacaacct tgaaggtaaa gtgacgaata gacagcttat
    37801 ttctctcttg ccgtttgtgg aagaccctga tgctgagcta gaagccttgg aagaagagaa
    37861 aaagaagaac atggaagaca tgccgatgtt taaccaagac aacacgaaac ccgaagacga
    37921 ggtagaggat gaagaatcag gagtattggg cgaagaggaa agccaatctg atttaccagc
    37981 agatggacaa ggccgaaaag caggcagatc agttcgataa ggtctatcag gaagccaaga
    38041 cttacttgga taaggaagtc aataagattt ttgataagtt ccaacgtgat tatggtctaa
    38101 gtcaggtaga agctagacaa gtcttgaaga acatgaaaga caagaaaaat ctgaatgaac
    38161 ttcgtaaagt acttgaagcg agaccgaatg atccaaatat ccaaagacta ctggctgact
    38221 tagatagtcc ggcttattct ttccgtatga agcgtctaga acgtttgagt gatgatttag
    38281 accgtatgcg tgaatctatc tatcattcag aaaagacagg ctcagacgcc ttttatagcg
    38341 acttgatgaa ggatagttac tacaaggcta cctttgacct gcagcagcag acaggactag
    38401 catacggctt ttctgggctt cctgagaacg agattaaaca tctacagtct tttagttggg
    38461 taggagatgg aagtacgtac tcaacaaaca tctggaagaa tacagggaag cttacatcaa
    38521 gcataaaaga tgaattactc ataagcctta tgacaggccg agatacacga gaaactgcac
    38581 aagcaattgc tgagcggttc aatgtggggc agaacgatgc aaggcgtttg gttcggacag
    38641 aatcagcctt ttttcataac caaatggagc tactcaacta tgaggaagcg gatatagaga
    38701 agtatatctt tgtggccgtc ttagacaagc gtacatcacg catttgtcag gagcatgaca
    38761 atcaggtcta tgatagggat aaggctgtcc ctggtgtcaa ttgtccgcct atgcaccctt
    38821 ggtgtaggtc tactactgtc ggatacgatg aggacgcaga ctacagcaag ttgaagcgca
    38881 gagcaaggaa tccagagaca ggtaaagttg agtacgtgcc tgccgatatg acttataaag
    38941 agtggtatag caagtatgtt gcgaaagatg taaaaaatga aatacaagat tataagaaaa
    39001 gtgacaaaac cgtttcaaga tataataccc caaaattgtt ttctgatgtt agtaacgcat
    39061 gggatgaaat tgggaggggt ggattatcga aagaacaact tgtagacttg ctagaatctg
    39121 aatatgaatt aggtaatttt tcgagcgata tagcaaaatt gataggagta agttctgctt
    39181 atatagatgt tagtagttta gctacttcat tagtgagaca tggacaacag tattccttag
    39241 atgaatttat gttaataaaa gaggcggttc aaaaacctta tttgattcta gataattcag
    39301 agagggttga aaaatcaatt atttcatatg taaaaatacc taacaaagat aaggtcatta
    39361 tggaagcggt gatggtgcca cgagatgaaa tgctagtcat tcactttaac aaggtgggga
    39421 ttcgtcaagt taaaaagaat gaaaaaaata tgtcgacgct ttacaaaaag ggaaaataat
    39481 gctatactct tggtaaagat agaggttgag aatctgtcac caacgcgcca cttatagtgg
    39541 gtcgagaaat gcaggagccc cgacagtcct gcctatctgt gcactaaaca atcgtttagt
    39601 gctttttttg tactcagaaa ggattgaaaa tggacacagc aagaattggg ataactaacg
    39661 tagaattttc aggaacaggc gaaaatgact cagcgacagt gaaattagag ttaaatattt
    39721 atggggcgga tacgttcagc gcgattgagt tactacctaa aatattaacc gacattcatt
    39781 cattatcgta tgaagttgat tgattgtgac attaaaagga gtgaaaacat gtttatttgg
    39841 gatttggtat caatcacttt tgggtggttg gtatttttgt ttttaacctt tattatttta
    39901 gcgttagtta gcgggataat tgatggcata aagaaaggaa cagaaaaatg gaagaatgga
    39961 aagaaagatt taaaaaagaa tactacgaat tgaaagaacg attccagaag ttagatatga
    40021 tgattgggaa atacgaaaaa gggcaactag agtttgaatc taaatgtccg attgatttgt
    40081 taaaaggtca gcgttcaacc atgtggaatt atttaagaat tctagaacaa cgtgcaaaaa
    40141 ttgaagaaat taaactataa aaattaaccg catcgaaatc gatgcggttt tcctatgccc
    40201 taaccgtatg gaatcccgta cggtttttat attgtccaaa ctgtaccgat gacaataaaa
    40261 gctgtgctgt tccgtcgccg gacgtaaaac gagattatcg agtggcgacg taatcgctgg
    40321 aggacaatta tgtcagaaga aatcaatgca actgtatcta ctgaatcaac tgagactgtc
    40381 gacactcaag gaaatgttga ttcagtgcag gaagaaaagc acgaacgaac tttcactcgt
    40441 gctgaaatcg gtaagatgct atctgccgaa cgctctaaat gggaagctga gcaagaagcc
    40501 aaggaaaacg aagctaagaa acttgccaag atgaacgctg acgagaaaca aaaatatcag
    40561 ttggatcagc gtgagcaaga actagctgac cgtgagaagg ctattgctcg caaggaattg
    40621 accgcagaag ctaaagcaat gctaagtgaa cgtgacttac ctgttgagtt agtaaatgta
    40681 gttgatttga caagcgcaga gacggtatcg cagtctgtcg ctgtattgca gaaatcatgg
    40741 gagcaagccg tgcaaaaagg cgttcaagaa aaactaaaag gcggagctcc aatgaaacaa
    40801 gcgccagtcg atagtgacgg tatcacaaaa gaagaatttg ctcgtatggg ttatcagagt
    40861 cgaaatgagc tctatcaaaa gaacccagag ctttataaga aattgaaagg ataatagaaa
    40921 atgacagcag gacaaactaa attagccact atggttaatc cagaagtaat ggcggatatg
    40981 gtagccgcta aattacctaa attgattaaa tttacaccgc tagcgtatgt agagacaaag
    41041 cttgaaggtc aaccaggtag cactttaaca gtgccagcat gggagtatgc aggagacgct
    41101 actgaaattg aagaaggcca agcaattacg ccagaccaat tgactactaa aaagactact
    41161 atgaccatca aaaaagcagg taaaggttat gaaattaccg atgagtctct tttgtcaggt
    41221 cttggtgacc cactaggtca agcgacttac cagcttggtt tagctattgc caacaagatc
    41281 gataatgatt tggtagcggt agctaaaact gcaacacaac atattacaga aactccaaca
    41341 actcttgagg caatcgataa agctctagat atctttgagg acgaagaaga tgcacagtat
    41401 gttgctatca tcaaccctaa agatgctact aagctaaaaa ctgcagtagc aaaagaatgg
    41461 attaaaggtt cagagcttgg agcaaatatg gttgtttctg gaaccttcgg tgaagttgat
    41521 ggtgtgcaaa tcgtgcgctc taaaaaagtt gatgaaggta aaggcttcct tgttaaagtg
    41581 tcaccaagtc aaactcagac agacgacgct aacaaatatg gagcttttgt tatcttgctt
    41641 aaacgtgatg tggctatcga aacagaccgc gatatcttga agaagactac cgtaatcaca
    41701 ggtgatgaac actacggcgt ttacctttac gaccctacac gagttgtaaa attcggtggc
    41761 gcgtaagagg tgacgatatg agtttattgc tacgacgtca ttatattcaa gaagagcagg
    41821 ttaaccagta ttctgattta gagaataaaa ctctagaaga gttgaaggat ctagcgaaag
    41881 aagcaggtgt agcaggcgct tataagttga caaaagccga aattgtagaa gttttggagg
    41941 aactaaaaag tgaaatttaa aatcaaacaa gatttctatg attgggaatc aaatgtgaaa
    42001 cgactggcag gagaggaact tgagattact gaggagcgct atgctgagct ggctgacaat
    42061 attgccagca acggtgtcac tatctcagac gttcttgaga aaatcctccc tgaacctgag
    42121 ttcttagaag aggattgata tgtctataga gttgctgaag aaattaacag gcgaagaaga
    42181 tactcagctt ctcatgttgc tccaaacaag ggctacaaat cttatcttgt cagagactaa
    42241 tcgcacatct ttgacacctg ctttaagtct tttaatacct gaggttgcta tcgaactcca
    42301 caaccgctca ggagcggaag gagagcattc tagaaccgag ggtggtatag cagtagtcta
    42361 cggagaaaac ggcctgtcta cggatcttct acagcgaata cgcatgcaca ggctagcaag
    42421 ggtggcaggt catgtttttg aagcagagta gactgaaacc ttatccaatg cgacggtttg
    42481 aaaagactgt cactgaggaa ggtgtcgcga aagaagggta tgccaaggaa gctgagacag
    42541 tccgccttga attgtggcca gctagtagca agctacaatc tgaattgtat ggcgagcgtg
    42601 tcaatgatat tttgaacgca aatgccaaca agtcagctac tatcaaagta aaagatggtg
    42661 tgtgtatcga tagtcagacg gaagtgactc atagggttat ttctaaaaag gtctacacac
    42721 atcatcaagt tttggagtta gagcgtgtca gggctactag gggcagatag gcttatagct
    42781 aaatgtagac gattggctag taaaaaaact ggcgaggata tcgtcttacg tgcggtgcac
    42841 aatgctacta taaaggttgt ccaagcagat gcaagaagac tcgcaccagc gagagatgga
    42901 gagcttataa ctagtatcaa aactagggca aaaatggacg gagataaggc tataggcgaa
    42961 gtttacacca accttaaata cgctccttat gttgagtttg gaacgggacc aataggacaa
    43021 gctagccatt ctggtatttc tccagaggtc agcgtgactt acaagtctag tccgtggtat
    43081 gtacatgaag accaaatcaa tgtaggaccg taccactttc aaaaaatcgg ggagttctac
    43141 aagatgtatg gtcaacctgc ccagccttat ctttatccag ctttgagaga caatcaagag
    43201 cgtgtgtcta agaatatttc gaattatgtc cgtagaaaga taagagaaca aataaaatga
    43261 ttaatatcaa gcctgttatt tataaagaat tgcaaaaggt tgcagataat gtgaccgata
    43321 cttatcctag cgattgggag actttcccag tcgttatttt tttggaagaa caaaacaagc
    43381 cgggtgattg gtttgatgac caggaacaaa aatcctctat ccgctacaag gtggatatct
    43441 ttgatgatac tagcactagt gagttagctg ttaaaatcaa tcagattttt gagtctttag
    43501 gtttgcgaag aactgactgc caagacgtgc cagacccgtc tcatttgaga cataaggtca
    43561 tgcgttttga aggtatcgtc gacttacact cagagcttgt ttttcaattt agaatggaga
    43621 attaaacatg ttagcaaatg gaattacgct ttcttatggc gaaacaaaag atagctatac
    43681 taaacttgtt ggattgaaag aagtaccaga gtttggtatt gaactcgaaa aagtagaaaa
    43741 tactactctt gaagatacgg tgaagaagta cgagtttggt attggggaca taggagaact
    43801 tgagtacaag ttctcttata ataattcaag cgcaactgct ccttatcgtg tattgcgtaa
    43861 ggcagcagac gacaagaaga aactctactt tgaacaagct tatccagacg gtactaaggt
    43921 catttttgaa ggccaagtat ctgttaagct tggcggtggc ggtgtcaatg ccgttatcga
    43981 tttcacactt aagattgcct tgcagtctaa tcttacattt actgatggta ttggaggtta
    44041 attaaatggc gttaaaatac acaacttgga aagttactga cgaaaaagag ttgaagctac
    44101 gtttgacatc tcatcaagct gcaactgtgg aagaaaaaat cggcatgaac ttgctgaaga
    44161 ttttcatgcc tgaagctggc gaagagttca ctttaccgcc tttgaaagtt atgttgttgt
    44221 tagttcacgg agccttgcag cagtatgaac atgggtattc tcttgaggat gtctatgatt
    44281 tatacgatga atacgtggac aatggcggag accaaacaac cttcatgaca gaggtgttga
    44341 tgccactctt tgaagtatcg ggttttactc cacgaggaag caaggacaag aaaacttcca
    44401 agaagaaaat gacagtagac aagtaatctt aacggtaact cagattattg agaggcttta
    44461 tcctatgttt ttggacatcg ggggcaagcc tcttgatttt tgggatttga cggtacttga
    44521 aatcagagaa atgattgaaa gctataaccg tgtcaaaatc caagagcgta aagaaaagat
    44581 tattgactca tacagacttt cgcagatgat atccaaccac gtttctttat tgttatccaa
    44641 agatgccaag gcctttgagt tctgggaata tgcgcctgag ttgtttgtag aagaacaaca
    44701 agcagtagaa caggaacgac agaaacaagc acttttgttg cataaggaac ggatgcgtga
    44761 atttgcagag agacataatc gaaaaaggaa ggaggaagta aatggcaact cttgatgaat
    44821 tgaaagtcat gattgacgct gagatagcgc ctttcaggaa gaagatgaaa gaagtcgaga
    44881 atcaggtcaa aggaacatct gaccaagtga aaaatgctac tgccaaagtt cgtgaacagt
    44941 cgagctcaat cggtagtgcg tttggcaagc tggctaagtt cgctggtttt gcaatccttg
    45001 gtaagaaatt acttgatgtt gggatgtatt caacgcagac ggctcttgaa gtatcagcgt
    45061 ctatgaacca aatcaagcga cagatgggcg agagttcgca atctttctta aaatgggtta
    45121 acgataatgc caacgctatg aatatgggtg tgggtgaggc taccaactac ggtgcagtct
    45181 actcaaactt attttctgga tttataaaag ataccaacaa gctaagcgcc tataccgcta
    45241 agatgctgca gacctcggca gttgttgcgg aaggctcagg gcgcacgatt acagacgtta
    45301 tggagcggat tcgctcaggt ttgctaggga acaccgaagc aattgaggac ctaggaatca
    45361 acgtcaatgt ggctatgatt gagtctactg aagcctttaa gaagttcgca aacggacaga
    45421 gctggcaaca gttggattac caaacccagc aacaaatccg ccttatggct attctggaac
    45481 aggctacagc caagtatggg aataccttgt ctaattctgt aaatggtcgt atcagcctat
    45541 ttaagtcgct gatgaaggac gcagcattga accttggtaa ctctatgtta ccgattatca
    45601 atgccattat gcctgtcttg aactcttttg cgatggtctt gaagaacgtt actgctaaac
    45661 tcgctgagtt tatcgctttg atgttcaaca agaaagcaac agtgaaagat ggtgttggtg
    45721 gagcagttgg agacatgggt aacgccatga aagacgctgc aggcggagca ggagaccttg
    45781 ctgacgcagt agacgacgct ggagattcag caggaggact tgctgacaat cttggagact
    45841 ccgccaaaaa cgctaagaag gccgctaaag agttgctagg tcttttggga tttgatgaga
    45901 ttaacatctt gcaaaaacca aaagatgacg acgcaggcgg ttctggaggc ggtggcaaag
    45961 gtggtaaagg aaagggaggc ggtggcggac ctttcaaaga catcttgcca gaagtcgagt
    46021 tgaccgacat ggacaacaaa ttcaagagca tttttgatgg tcttggagat aagctcaaag
    46081 ggttgtttga cctcttcaag aaaggttttg atgcagcatt tagaccagaa ggtataaaac
    46141 gcattaagac tgccttagac caaatagcta agacaatggg agaaatcgtc actgacccaa
    46201 gggttgtgaa tgcctttaac cgaatggctg agaaaattgc ttatgcttta gggcaagtga
    46261 caggctcaat aaccactatc gggctaggta tcggtgtttt ccttgccgaa agtattgcaa
    46321 atggccttgg aaggcaaaaa gaacgcatta tcagggcgct agtcgctttg tttgataatg
    46381 ttggtaacct ttccgaggca gtaggaaaca tagctcagga cttttctagt gctttctacg
    46441 acgtcattac ctcaactggt gcggttcgta tcggtagcgc tattgtgtca actctgttga
    46501 gtttgacatc taccattgtt gaagttggta gtaaattagc aggaagtttg tttaaaggtt
    46561 ttgaaaaagt cgttgtgaca agcgctccta aaatttcatc agtcttccaa agtttattag
    46621 atactgttgc gcctgtattt gagagcattg aaaggtctgt taacaaattt ggcgatggct
    46681 taagtcgtgt ttatgatgaa catgtagtcc ctgctattaa ctctattgct aatgctttta
    46741 atgggctaat tgacattatt cagattctct gggagaattc ctggcaacct tttgctgagt
    46801 ttttatcagg agtattcggt gttagtattg aaggaatttc agatttatta ggaggtggcc
    46861 ttttagccac tttgggacta ttggcggatg ctattaagtt agtggcagat ggtttcaccg
    46921 ttttttctga ctggtgtaaa gaaaacaaag aacctatcgt agctttgata acaacttggc
    46981 aaacgattaa tttcttatca tgggcagaac aagctggagg acttgcagga gcattcagct
    47041 tgttaggtag taaggtctct ttgattgttg gagggattaa gaatctaggt cttgctatta
    47101 aagcattgac atttgataag ttggtcagtt ttggtgaaac aatctatttg aacaccttat
    47161 atgcaaaaga ttttgtggtc aattcaggta aaacaattgc acagctagga aaaactgctt
    47221 tagaacttgg taaatcagct ctagcatgga ctgctcatgc agcgaaaatg ggattagcaa
    47281 ccgcggcgaa atttgcacat tctgttgcaa caggagtcgc tacagctgca acatgggctt
    47341 ttaatgcagc gttagcagtt ttgacaagtc caataacatg gattattgca gcaatcgcag
    47401 ccttaattgc tatcggtgtt ttgctctatc aaaactggga cactgttgtt gagtttgcta
    47461 aaactgtatg gcaaggacta tgtgatttta tcagtggtat ttgtcaagcg attggcgaat
    47521 ttttcagcgg tctatggacg aaactacaag aaatctttga gccgataggt caatggtttg
    47581 gcgagaaatt ccagcaagca tgggacgcca ttgtaaacat attctctggc atcggagagt
    47641 ggttctctgg tgtattccaa ggtgcatggg acgctatcgt taatatcttc acaccaatcg
    47701 gctcatggtt cggacaacgt tgggcagatg tgactaatgc gttatccagt gtttcaaact
    47761 ggtttggtga gatgttcact aatgcttaca acgcagtaaa agatgctttt agttctattg
    47821 gcgacttctt taaaggcgtt tgggatactg ttaaaagtat cttcgtaaat gctggtcaga
    47881 tggtcggaga ggcagtaggt ggagcgttta agagtgcggt caatgcggtt cttggaacga
    47941 ttgaaaatgt agtcaatggc ttcatcggaa tgattaatgg agttttaggc gttgtcagaa
    48001 acttacctgg tctaggatgg gttggtagtg taagtacagt tagcctccct cgtcttgccc
    48061 gtggtggtat cgtcgatagt ccaacaatcg ccatgattgg tgaagctggt aaagaggcgg
    48121 tcgtaccact tgaaaataca ggatttatcc aaacacttgg acgagtagtc agcagtgcgg
    48181 tagtaaatgc catggctggt gttagtccac aaggtggatt ctctggcgac ggcgacatcg
    48241 ttatccaaat cgcaggccat gagttcggac gggtagccat ccaagaaata aacaaggaac
    48301 atgaacgagc aggtcaaacc ttgctcaaga tttaggaggt taaatggcac aattgacaat
    48361 caatggggtg gctgtgaagc ctcccaaata ttttcaagtc ggtattcaag atatcgatgg
    48421 agagacaggg cgtaatgcca atggcgacat gatgcgtgac cgtatcacga ccaaacgcaa
    48481 actagactgt gaatggggta tgatgactca gggagaatta agtcagcttt tacatgctgt
    48541 atcatctgaa ttttttgagg tatcttatcc agaccccatg gatggccaag tcacaaagac
    48601 tttctatgtc ggtgatagga cagctcctag ctataccttt actgagaagt ttaaaccttg
    48661 gtctggcgct aaatttaatc tggtagagag gtaagaaaat ggacgcttta actagacgac
    48721 aatttgacag agccatgttt gccaaggaaa ggacgctggc tattcgtgtt ggtgattatg
    48781 cttcacggga tatcaaagag gctagttttg agtatggcta cattaagggc gatacttata
    48841 agcctggtgg aacctgcgct ggtagcggta aaattacctt taccagtatc attaccacgt
    48901 tcaataagct ggataccctg caccctgaga ttggtctact ggttggggat acctaccagt
    48961 gggtcaagat gggggaatac ttcatcaacg atattgagat tgaccgaaac cgaaacacta
    49021 ccacacttga acttatggat ggtatgttta agctcaatcg tgagtatgtg acagatttgc
    49081 atttcccagc tgaagtacga gaggttattc aggaaatctg cctgaaaaca ggcattgagt
    49141 tagcgaatga ctatttcgga atcagcgcga tgcgttatca tattgagcaa gttcctgagg
    49201 gcaagaaact ttcctttagg gatatgctga gcgctatgac tcagatgatt gggatgtctt
    49261 gtttcttcaa cagagaaggc aagatggaaa tccgtgattt gactgagtcc aatatcacga
    49321 tcaacgctga cagttacttc ttgcatggct tgaccaagag tgagattgag tatcagatag
    49381 ctggtatcac ttgtaagacg gacaagaagt ctctgacagt cggtatgaag acaggtcggt
    49441 ctttggaact ggacaatgtc tttatgactc agagcgcttt aaatgacttg tattacaaac
    49501 tgaaaaacct aacttactat ccgtataatc tcaactacca aggacatttg ttacttgagg
    49561 ttgggcagtg ggtaaccatt cagaccaaca agaaagagac ttttaaagtt cctgtcttaa
    49621 gtcagagctt tatctttaaa ggtggtctga gaggtcgtat cagtgcagat agtaaggctg
    49681 gaaacgatac ccagtattcg tacgagggaa cgattaccaa gcagataaag caacaagatg
    49741 gcattgaagc aaaaatccaa gcgcagattg aagcagcaga taaagatttt gaccaaaagg
    49801 tcgacaaaat caaaaaagac tttaacgatc aagtagaatt ggccaaagcc agagctgaag
    49861 aagtcaagag agaactgtct gacactatca atcagcgatt taatagcttt gacaacgggc
    49921 cattgaaaga aactaagcac aaggctgagg aagctttgcg aaatgctggc gcaagtaccc
    49981 tgcttgcaca ggaagctaag cggattgggc tggattctgt tgctagactt gaagcgttta
    50041 agtcgcagac tacgagcgca caaacggctc tgtcgggtga cttggacgct ctgaaacgga
    50101 ctatcgcgaa tgatattcga ccgaagcaag cacaggctga agctgagatt gccaagcaag
    50161 ttgaagcact tagccggact aagaatgaac tggctggcgc aagtacccta cttgcacagg
    50221 aagctaagcg gattgagctg gattctgttg ctagacttga agcgtttaag tcgcagacta
    50281 cgagcgcaca aacggctctg tcgggtgact tggacgctct gaaacggact atcgcgaatg
    50341 atattcgacc gaagcaagca caggctgaaa ctgagattgc caagcaagtt gaagcactta
    50401 gccggactaa aaatgaactg gctggcgtga agtcagcgca agcgacgtat gaggagacga
    50461 cgactcgtag actgtcagaa ctgaccaact tggccaatgg taaagccagc aagtcagaac
    50521 tcacgcagac agctgaggag ctctctagta agatagcgag tgtgcaagtc ggaggaatta
    50581 acctcttgcg taatactgcg agtttgttga ttggcgatcg ttcaaaagga tgttggatga
    50641 gttcaagcgg aggaaatggg cgagcgatta gcgtagaagt tttggctcct ccccaaaaaa
    50701 tgataaaaaa catgattcgt gttattgaaa atacgaatgg tggaaataaa gatttaactc
    50761 aacttgttag attgcgaatt ggtgaaaagt acacgatttc ttgttatgca agggttgcta
    50821 gcgatagccc aaatgcaaac gtgaacttgc tatttcgttc gtgggcaaat gataccgatt
    50881 taaatcgcaa atttcagaaa tccatctctc ataaaaattg gcaaaaatat tcatttacat
    50941 ttactgctga tgcaattgaa aattcaattc aatttggaca atctggcgca ggaattatcg
    51001 aaatatgcgc tccgaaaatc gaatcaggaa cgttagcgac tgattacagc gaagctcctg
    51061 aagatataga aggtcagatt tcaacagttg aatctacctt caaacagcgt gctgattcac
    51121 tcgacgctgg tgtaagaagc ttgactgaag gccttagaac caaagcggat atcagctcac
    51181 tcaatgtgac tgctgagaat attaggcaat ctgtgaagag ccttgagaca gacacgcaga
    51241 acaagctaaa tcagaagttg agtcaggctg aatttgaggt gcgagctggc tctatccgtc
    51301 aggaaatcct gaatgcaacc aaggataaag ccagcaagtc agaactcacg cagacagctg
    51361 aggagctggc tagtcggata gcgagtgtgc aggcatccgg tcgaaatcta ttcttgaact
    51421 cactattcaa gcaggatatt tcaaaaacag gaatttggac aacgagtaca tatacggctg
    51481 ctatcgatag cgaaagtaag tatcttggac acaaggctct taaaattata ggtctgaatc
    51541 catctggccg tgatggaggt aatcccaagg ttacttatcc agctctgggt caattcggga
    51601 aagtaattcc cggaagtacg actaatcaag atgtaaccat tagtttttat gctaaggcaa
    51661 ataaaaatgg aataatgcta agatctcgat tagggaatat cggatataaa actggaaatg
    51721 tgacattgtc gacagaaatt aaacgatatg ttgtccatat tccaaaaggt tggacaaacg
    51781 aatctaagca gaccacaaat gaatggttgt tcaatttcaa ccaggaagga accgtttgga
    51841 tttggatgcc gaagtttgaa ataagcgatg tagatacttc ttattcagaa gctcctgaag
    51901 atatagaagg tcagatttca acagtagaat cgatcttcaa acagcgtgct gattcactcg
    51961 acgctggtgt aagaagcttg actgaaggcc ttagaaccaa agcggatatc agctcactca
    52021 atgtgactgc tgaaaatatc cggcaatctg tgaagagcct tgagacagac acgcagaaca
    52081 agctaaatca gaagttgagt caggctgaat ttgaggtgcg agctggctct atccgtcagg
    52141 aaatcctgaa cgcaaccaag gataaagcag ataagactct tgtcgtgact gaagctggga
    52201 aattgcgaga agaattttca aaaatgaagg tgggaggccg gaatctatgg ataaaatcca
    52261 aggcggttgg agctgtaatt gaaaaattac ctgaaaacca cgtcacaggt caaaaagaat
    52321 gctataggct agagaacaac tctactttaa cgttcaacct tgaaccagat ttcagctcaa
    52381 ggttgtacca aaaagttact tttagcgctt ggatcaagta cgaaaatgta gtccaaggtc
    52441 gaaatttttg gaatgtattt aattgcttca aacattatct ttttagaaaa aatagtgaga
    52501 ccggagtaca gagtggtcca gattatgcta cgcttggtat gtataaaggt tcggcagatt
    52561 ggaaatatat tacattcact tatgactact ctgaaaaaac aaattttgat caattgaaga
    52621 catcattgcg attcaatctt gaaggtgcta caagcggtac agcttgggta acaggaatca
    52681 aggttgaaat cggtagtgtg gcgacggact ggagtcctgc gcctgaggac gctgatggtc
    52741 tcatcactga ggctaaggct atctttgagc ggacagctca gggcttgcga accgatttat
    52801 cagctattca ggaatatgta aataaagacg gtcagcgaca ggaagcccta cagcgctata
    52861 ctcgtgagga gagcacgaga caagcgacag cagtccgtga gctggtcaat cgtgatttcg
    52921 ttggtaaggc tacttatcaa gaagatgtta agggtatcaa tcagaggatt gaagctgtta
    52981 aaactagtgc gaataaagac atcgctagtc aaatcgctag ctatcgtcaa tctgtagatg
    53041 gtaagttcac ggatatttca agtcagataa ctacttataa gcaagatgtg ggcggtcaaa
    53101 tcagtggtct atcaaataga cttacaagca gtgagcaagg aaccactact cagatttcaa
    53161 atctttcaaa tcggataaac agtaataagc aaggcacaga taatcagatt tcaaatttaa
    53221 agactcaggt cgctacaaac aaagcgaatg ctgatagtca atttgcgaat gtgaccaatc
    53281 aactagcgcg aaaagtagag actactgact ttcagcgtgt taaggaaacc agtaaacttt
    53341 acgagcggat tttgggcaat actgaaaatg gaattgcgga taaggttgct cgcatggctc
    53401 tgaccaatca actgtttcag gttgaggttg ggaaggttgc caaaggtggt cgaaattata
    53461 tcagaaatgg tcaatttaag aacggttcga aaaactggct tgaatatcaa tctgttaatt
    53521 ttggtttgaa tttcaactat caacactctc aaaatcctaa taatcgaaat cggccagggg
    53581 ctcatttctt ccacgactcg caaaatatct ctaatttctt tggtttgcaa cagacttttg
    53641 cttttgaagg tgttcgagga gaaaaagtga gtgtatctct tcttgtttca aaggatggca
    53701 gtgatagcta cagcggtttg aaagttgcat tgcactacat caaaaacaaa aacattattg
    53761 ggcaagagtg gcaaaatatc ccaagtccac aaataacatc gaagtataag cgtttcacat
    53821 ttacgtttac tttatcagac gatgtagaga atctgaattt gatgttgttt ggtgaaaaag
    53881 ggaagaccat caacctctat gttacagatg ttcaactcga aagaggttct gtcgcgacgg
    53941 actacaaaga agctcctgaa gacacggacg aagcgattcg ctctgttcaa agccaactaa
    54001 ctggctcatg ggcagttcaa aacatcaact cggctggagc tatcatctct ggaatcaatc
    54061 ttggcgccaa tggacataac cgctttgttg ggaaattgac ccacatcact ggagagaccc
    54121 tgattgacag agcagtcatc aagtctgcca tggttgataa gctcaaaacg gccaattttg
    54181 aagctggttc ggtcacgact acgatattag acgctgaagc ggtaactgct gagaagttga
    54241 aagttgacaa tgcgcttatt agaaaattaa ctgcaaatga tgcttttatt gaccaactga
    54301 tatctaaacg tatcttctct attaaggttg agtccgtcat ttctagttca accttcctag
    54361 aagcctatca aggtcgaatt ggtggattca cacttggtca atttgaccag ggtggcggtc
    54421 gctggatttc aggtgtcaat cagttctctg ttggtatggg gaatggtgcc gggtatggag
    54481 tccggacagc cttctgggcg aactggggaa ataattggaa ctatgccgga cctaaagcat
    54541 ggaacgtcaa tactgatggg aaaatgtact gtaggaatga agtcggtttt tatgatcaag
    54601 tggatttttc gaattcatcg agagcaaact tctatgggaa tactactttt tctcgttctc
    54661 ctgtgttttc aaatggtatc gaacttggaa gtaaagatgt gcttggtgat ggctggaatc
    54721 ccaaaggcgg aaggaatgcg gttgtttggt ggaatcaggt cggtagcggt agcgtgaagt
    54781 attggatgga acaaaaatca gacagacgct taaaagagaa catcacagat acagctgtga
    54841 aagccttgga taaaatcaac agattaagaa tggttgcatt tgatttcatc gaaaataaga
    54901 aacatgagga gattggtcta atagctcaag aggctgaaac catcgttcca agaattgtct
    54961 cacgagatcc tgagaatcca gatggctatc tgcatattga ctataccgct ttagttcctt
    55021 acttaatcaa ggctattcaa gaattaaatc aaaaaataga aaaaatggag aaaacaatag
    55081 catgagtaac aacatgttga tcaacatcgc acttaaagca attcaggagc ttgctcttga
    55141 aaatagaaaa cgaacacaca gattggagaa cttagaaaat gaacacagaa cagcttaacc
    55201 aagccttacg aatgacaatt agtgaaatat caataacttc aacaaattcg atgattgaaa
    55261 gtaatatctt gagtattcag ttggatgagc aaagggaaga gaatcaaaga cttcaagcac
    55321 gagtggatga gctggaagct ctgcttgatg aacaaactaa accagcagac aaaggagaat
    55381 agacatggca gaaacaaatc aaaacacaga taacttacta gaccttacaa aaatcacaga
    55441 accatttgat cttgcgagtg ctttgcgcta catgaaagaa aatggagagt tcattcgttg
    55501 caagaatgta agcgatgact tctatatgta tcgtgacgtt caaaaacgtc ctgtgatcgt
    55561 aaatggccgt cgccaattca aggatgttga aaccgtttgg gcattcaacc agtggggtgg
    55621 tacaatcgca acaatcaacg tagccgttct gttgaatcat gaattctata tcatgaaatt
    55681 tgatgcagag ggcaatcctg actggacggt tccaacggta gaacctaaag aataggaggt
    55741 tgtatgccaa ttgaagaagc tgaaaaaatc gctcaaagtc aggtagcttg ggcgattttg
    55801 tttatcttgc ttttttttat tatcattcga tatcttatca agacttcgga caagcgagag
    55861 aagaagatta tggatttgca cgagcaatca aaggccgact ctaatagacg agaagagcgt
    55921 ttgatgactc acctagaaaa gaccactaca gaattaacca caatcactca cacggtcgga
    55981 gacattcaaa aagaaatggt tcgcatgaac gaccgcatgg aagaaatcga aaaaggagaa
    56041 taacaaatgc aacaaattac tgaaatcatt actaatggag caatcagcat ccttgttatt
    56101 ttggctggta tcgcagtcaa ggcagtcaag gaatacctcg tcaaaaaagg tggagaaaag
    56161 actatcaaga ttgttgaaat cttggctaag aacgcagtta atgccgtgga gcaggtagct
    56221 gctgaaactg gctacaaggg agatgaaaaa ctggcacagg ctcgtgctaa agtccgtgct
    56281 gagcttacaa aatacaatat cagtatgacg gacaaggact tagacacctt tgtggagtca
    56341 gccgtgaagc agatgaatga cgcttggaaa ggacaagagt aatggatatc gatagaaaca
    56401 gactacgaac aggcttgcca caggttgggg tgcagcctta tcgacaagta catgctcact
    56461 caacaggcaa ccgcaactca accgtacaga atgaagcgga ttatcactgg cggaaagacc
    56521 cagaattagg ttttttctcg cacgttgttg ggaacggtcg catcatgcag gtaggacctg
    56581 tgaacaacgg aagttgggat gttgggggcg gttggaatgc tgagacctat gcagcggttg
    56641 aactgattga aagccattca actaaggaag agtttatggc tgactatcgc ctctatatcg
    56701 aattgctacg caatctagcg gacgaagcag gcttgccgaa gactcttgat acagacgact
    56761 tggcaggtat caagacgcat gaatactgta ccaataacca accaaacaac cactcagacc
    56821 acgttgaccc ttatccatat cttgctaaat ggggcattag ccgtgaacag tttaagcaag
    56881 acatcgaaaa cggcttgagc gctgcaacag gctggcagaa aaatggcact ggctactggt
    56941 acgtacactc agacggctct tatccaaaag ataagtttga gaaaatcaac ggtacctggt
    57001 attatttcga tggctcaggc tatatgcttt cagaccgctg gaagaagcac acagacggta
    57061 attggtacta ctttgaccaa tcaggcgaaa tggccacagg ctggaagaaa atcgctgaca
    57121 agtggtacta ttttgatgta gaaggtgcca tgaagacagg ctgggtcaag tacaaggaca
    57181 cttggtacta cttagacgct aaagaaggcg ccatggtatc aaatgccttt atccagtcag
    57241 cggacggaac aggctggtac tacctcaaac cagacggaac actggcagac aagccagagt
    57301 tcacagtaga gccagatggc ttgattacag ttaaataaat agaaaggaaa ctttctaaat
    57361 tgttctttca ccgcaggctc aggcttgcgg tttttttgtt tgctcaaaag gggcaaaaaa
    57421 ggggcaaaag tgtcgtaaat ctctgtaaaa tgatgtaaaa acatttattt aaaagctcaa
    57481 aatatagctg ttttaaaagg tattgtaaga tatagtaaaa cgatgtaaag gtatttttaa
    57541 atgcggatga attataaaac cacgaatcct atgtgactcg tggttctttt ttataaactg
    57601 gtagagtgtt ttggttgtac tttttgttca gggtcaatgt agttgatagc gttgttgaca
    57661 gcagttggag cttctccgag gcctgtcgca atcagatcaa tttttccgtc atagtagcag
    57721 cagtcaccga tagcatagat acctgcttgg ctggattctt gtttgctgtt gacgataatc
    57781 ttgtgacggt tgaggtcgag cccccagttt ttaaggttac cgacagaaga tttgaaacca
    57841 tagttgacaa agaggtggtc taggtcaatg gtttcagttt catcagattt gacttttgtg
    57901 atttcaagtt tatcaagtgt ttttccattt ccaaggagtt ggccaggggc gaatggtgtc
    57961 ttgatggtta cagatgattc ttgcaaggct tgaacactgt gttccaaggc acggaaatta
    58021 tctctgcggt gaacaagggt agttggtgcg attttttcaa aagccaaagc ccaatccaca
    58081 gccgagtctc ccccaccaag aatcgtcact ttcttaccag cgtattgctg aatgttagaa
    58141 acgtggtagt ggatattttc atagccctca accccttcaa gttccagcgg acgtggtttg
    58201 aaggcaccgc cacccatagc gatgataact gttttagtca ggtgacttcc tttagaagtt
    58261 gtgatggcaa attcttcttg tttgtcaatc tcaagaaccg tttcattgag atgaataggg
    58321 gtatcaaatc catttagctg ttcaatcaag cggttagtca actcttctcc agtcaggttt
    58381 gggaagcctg gtacgtctag gatttccttt tcagggtaga gaatagcagg ttgtccacct
    58441 agctggggaa gagagtcgat gatttgaacc ttggcttggc gtaggtgggc ataaaaggct
    58501 gcaaaaagcc cgacaggacc accacccaca atggtaatat catagagttg agacatagtt
    58561 tctcctttgt tttttctagt cagtttattt tatcatattt ttgttcaatg taaaatggac
    58621 taggataggg aaaaaaatgc ccgaaaatgg tataatagga cgaaagtgtt ttgataggga
    58681 ggatatcagg gatgaatttt caacaattat ccaatctgca atattggacc agtttgtttg
    58741 caagtccatg gacgatagct atcaatctga ttgatatttt gattgttgct tatattttat
    58801 accattttac aaaagctatt gcaggaacca agattatgat tttggtacgt ggagttttgg
    58861 tatttatttt agctcaaatc cttgcaaata tgattggttt gactacgatt tcttggttaa
    58921 tcaatcaaat tattacttat ggggttattg cggcggttgt tatcttctct ccagagattc
    58981 ggactggttt ggaacgtttg ggaagagcga cagatttctt ttccaatgcc cctattagtg
    59041 ctgaggaaca gatgattcgt gcctttgtta agtctgttga atacatgagt cctcgtaaaa
    59101 tcggggcctt ggttgctatt cagcgtgtac gtaccttgca ggagtatatt tcgacaggaa
    59161 ttcccttgga tgctaagatt tctgcagaac ttctcattaa catttttatt cccaacactc
    59221 ccctacatga cggtgcggtg attatcaaag aagaacgtat cgctgtgacg tctgcctatc
    59281 tgcccttgac aaaaaacaca gggatttcca aggaatttgg gaccagacac cgggcggcta
    59341 tcggtttatc agaagtctca gatgccttga cttttgtcgt atcagaggaa acgggaggaa
    59401 tttcgataac ctataatgga aggtttaagc acaacctaac acttgatgaa tttgaaacag
    59461 aattacgtga aatcttactt ccaaaagagg aagtgggtct tagttttaaa gaacgattgc
    59521 taggaggatg gaaacatgaa aaaaaatagt ttatatatca tatcctcact cttttttgct
    59581 tgtgtcttat ttgtctatgc tacggcgacg aattttcaaa acagtaccag tgctaggcag
    59641 gtaaaaacgg aaacctatac taatacagta acaaatgtcc ctattgacat acgctataat
    59701 agtgataagt attttattag cggttttgct tcagaagtat cagtggtctt gactggtgca
    59761 aatcgcctat cgctagctag tgaaatgcaa gaaagtacac gtaaattcaa ggttactgct
    59821 gacctaacag atgccggtgt tggaacgatt gaagttcctt tgagcattga agatttaccc
    59881 aatgggctga ccgctgtggc gactccgcaa aaaattacag tcaagattgg taagaaggct
    59941 cagaaggata aggtaaagat tgtaccagag attgacccta gtcaaattga tagtcgggtg
    60001 caaattgaaa atgtcatggt gtcagataaa gaagtgtcga ttacgagtga ccaagagaca
    60061 ttggatagaa ttgataagat tatcgctgtc ttgccaacta gcgaacgtat aacaggtaat
    60121 tacagtggtt cagtaccttt gcaggcaatc gaccgcaatg gtgttgtctt accggcagtt
    60181 atcactccgt ttgatacaat aatgaaggtg actacaaaac cagtagcacc aagttcaagc
    60241 acatcaaatt caagtacaag cagttcatcg gagacatctt cgtcaacgaa agcaactagt
    60301 tcaaaaacga attaaaaata gaaaaggatt ttataacaat gggtaaatat tttgggactg
    60361 atggagtccg tggagaagct aacctagaac taacaccaga attagccttt aaactaggac
    60421 gttttggagg ctatgttctt agtcaacatg aaacggaagc gccgaaagtc tttgtaggac
    60481 gtgacacacg tatttcaggg gaaatgctgg aatcggcctt ggtggcaggt ctcctttcag
    60541 tagggattca cgtatacaaa cttggtgtcc ttgcaacacc agcagtagct tacttggttg
    60601 aaactgaagg agcaagtgcc ggtgtcatga tttctgctag ccacaaccca gcccttgata
    60661 acggaatcaa gttctttggc ggtgatggct tcaaactaga tgatgaaaaa gaagcagaaa
    60721 ttgaagcctt gctagatgct gaggaagaca ctcttcctcg tccaagtgca gaaggcttag
    60781 gaattttggt agattatcca gaaggcttgc gtaagtatga aggatacctt gtttcaactg
    60841 gaactcctct tgatggaatg aaggttgcct tggatacagc taatggagca gcttctacca
    60901 gtgcccgtca aatctttgca gaccttggtg cccaattgac ggttatcggg gaaacaccag
    60961 acggtcttaa catcaacctt aatgttggtt caacacatcc agaagccctt caagaagtgg
    61021 tcaaagaaag tgggtcagct attggtttgg cctttgatgg agacagtgac cgcttgattg
    61081 ctgttgatga gaatggtgac atcgtcgatg gtgacaagat tatgtatatc atcggaaaat
    61141 acctttctga aaaaggacaa ttggctcaaa atacaattgt gacaactgtt atgtctaacc
    61201 ttggtttcca caaggccttg aatcgcgaag gtattaacaa ggcagttact gcagttggtg
    61261 accgctacgt tgttgaagaa atgagaaaat caggctacaa ccttggtggt gaacagtctg
    61321 gtcacgttat cttgatggat tacaatacca caggtgatgg tcaattatca gcagttcaat
    61381 tgactaaaat catgaaggaa actggtaaga gcttatcaga gttggcggca gaagtaacga
    61441 tttatccaca aaaattagtt aatatccgag tggaaaacgt catgaaggaa aaggccatgg
    61501 aagtgccagc tatcaaggcc atcatcgaga agatggaaga agaaatggcg gggaacggcc
    61561 gtatccttgt tcgtccaagt ggaacagaac ccctcttgcg tgttatggca gaagcgccta
    61621 caacagaaga agtagactac tatgttgata ccatcacaga tgtagttcgt gctgaaattg
    61681 ggattgacta aatcctagaa aactagatga aaataaaaaa ttatggtaca atagcttata
    61741 atattgtagc cgatggagaa agacatgaat cttaaacgtg aacaagaatt tgttagtcag
    61801 tatcattttg atgcgcgtaa ttttgaatgg gaaaatgaaa atggagctcc tgaaaccaag
    61861 gtggatgtga atttccaatt gctccaacat gaccaagaaa atcaagtgac ttccttgatt
    61921 gtcatcttga gctttatgat tgtatttgat aagtttgtca ttagtggaac aatctcacaa
    61981 gtaaaccata tcgatggccg tattgtcaat gaaccaagtg aattgaacca agaagaggtg
    62041 gaaaccttgg ctcgtccatg tttgaacatg ctcaatcgtt tgacttacga agtgactgaa
    62101 attgcattag acttaccagg aattaatttg gagttctaat atgaaattag ctgttttcac
    62161 agattcctct gcttatctca gtgaagagac cttgcaaaga gaagacttgt ttgtcttgga
    62221 tattcctgtc aatattgatg gtgaggaata tgtcgaaggc atcaatctgt ctgctgagga
    62281 attttaccaa aaaatggctc aggcttctga attgcctaag accagtcaac caagtattgc
    62341 caagttagat gagatcttaa cttcgctcaa agaacaaggc tatacacatg ccttggggct
    62401 tttcctatct tctggaattt caggttttta ccaaaatatc cagtatatgg tcgatgacta
    62461 tgagggctta accattgctt tcccagacac tttgattaca agtgctcccc taggcatcat
    62521 ggttgaaagc gtctttaatt ggcgtgatca gggcgatgat tttgccagca ttcaggataa
    62581 gctagccatt caaatcagcc gtacgtcagc ctttatcatg gtagatgact tggatcattt
    62641 ggtaaaaggt ggacgccttt caaatggggc tgccattttg ggcaatttgc ttagcattaa
    62701 gccaatcctt tattttaacg atcaaggtgt gattgaagtt tacgaaaaag ttcgtactga
    62761 aaagaaggcc accaaacgct taattgaaat tatcaaggaa acaacggctt caggtcaata
    62821 ccgggtcatt gtcattcatg ggaatgctcc tgaaaaggct gaagaattgc gtcagcattt
    62881 gcttgatttt ggcttgggtt cggatgtttc acttgctaca tttggtagtg tcattggaac
    62941 gcacctagga gcaggaagta ttgctctggg ttatattcca gtgatttagt aggcacttct
    63001 aggctagtta atcttagcaa ttgaacacgg actacctgcc tcttgaaaaa agatgtctgt
    63061 cttgcctttc gtggaaagtc agtgccattc cctatttttc atgggtggct aagatccttt
    63121 gtattttgat aattgaacac gcctggaacc ctgtgtgaaa aagatagttc ttccaaggag
    63181 tagacacttc ttgatcagaa ttcctatttt cactttgtgt tcttacaggc tttgtatctt
    63241 agacaggagt agagatgagt attcgagtaa ttattgccgg ttttaaggga aagatgggtc
    63301 aagctgcttg ccagatggtc ttgcctgatt cagatttgga cttggtagca gttttggatc
    63361 cttttgagtc tgagtcagaa tggcagggta ttcctgtttt caaggataag gctgatttag
    63421 ctggttttga agcggatgtc tgggtagact ttactactcc agctgttgcc tacgaaaata
    63481 cacgttttgc tcttgaaaat ggctttgctc cagtagttgg aacgactggt ttcacgagtg
    63541 aagaaattgc agagctaaaa gaattttctc gtgcccaaga cttgggtggc ctgattgccc
    63601 ctaactttgc cttgggtgct gtcttactca tgcaatttgc gacgcaggct gccaaatatt
    63661 tcccaaatgt ggagattatt gagctccatc atgacaagaa aaaggatgct ccgagtggaa
    63721 cagccattaa aacagctgag ttgatggcag aggttcgaga gtccattcag caaggtgcag
    63781 cagatgagga agagctgatt gctggtgctc gtggtgctga ctttgatggt atgcgcatcc
    63841 actcagttcg tttgccaggc ttggtagctc atcaggaagt catctttggc aatcagggag
    63901 aagggttgac cctccgtcat gactcctatg atcgcatctc cttcatgaca ggagtcaatt
    63961 tgggaattaa agaagttgtc aagcgtcatg agcttgtcta tggattagaa cacttattat
    64021 gagattaacg caaatgcctt ctgaatttca gaaggcttta ccagtattag aaaaaattaa
    64081 agaagcaggc tttgaggctt attttgttgg gggctctgtt cgagatgccc ttctccatag
    64141 ccctatccac gatgtggata ttgcgacgtc ttcttatcca gaagagacca agcagatttt
    64201 tccgcgaaca gccgatatcg gaatcgagca tggaaccgta ttggtcttag atggggatga
    64261 ggagtatgag gtaacaacct ttcggacaga ggatgtctat gtggactatc gcagacccag
    64321 tgcggtttcc tttgtacgat cgctagaaga agacctcaaa cgccgtgatt tcacagtcaa
    64381 cgcctttgcc ttggatgaga caggagaaat cgttgacttg ttccatggtt tagaagattt
    64441 ggaaaagcaa gtcttgcgag cagttggagt ggctagtgag cgtttcaacg aagatgcttt
    64501 acggattatg cgtggtttcc gttttcaggc tagtcttggt tttgcacttg agccagaaac
    64561 atttaaagct atgaagacct tgacgccgct tttggagaaa atttctgtag agcgtacctt
    64621 cgtcgagttt gataaactct tgctggctcc attttggaga aggggcttgg cttccatgat
    64681 tgagagtcaa gcttatgact atctccctga tatggcatct agccaggaca agctcaacag
    64741 actgtttgat ttggagactg attttacttt tgaatcctct gaacaagcct gggcggcttt
    64801 actatgggct ttggagattg aaaatgcgca gtcatttttg aaatcttgga agacctcacg
    64861 ccagtttgcc aagcaagttc aggatttgct gattattttg gctctgcgtg aaaatggaga
    64921 attgagcaag cgagattgtt atcgctttga catagatttg cttttacagg ctgaaaatct
    64981 tcgtcaagct cgaggaaaag aagtcaaccc acaagccatc acagaaaaat accaaagctt
    65041 gactatccat gacaagaaag agattcagat taatggcgat attttgatca aggaatatgg
    65101 ctatcagcca ggcccagact tgggagagat tttaacagag attgagtttg ccattgtcga
    65161 tggagaattg gagaataatc gtgaagccat ccatgcttac ctgagggaga aaaaatgagt
    65221 gattttatcg ttgaaaaact aagtaaatcc gttggtgaca agaccgtttt tagggatatt
    65281 tcctttatta tccatgactt agacagaatt ggtttaatcg gtgtcaatgg gactggcaag
    65341 accacccttt tggacgtcct ttctggtgtt tctggatttg atggggatgt cagtcctttt
    65401 tcagctaaaa atgattacca gattggttac ttgactcagg atcctgattt tgatgataga
    65461 aagacagttt tggatacggt tctatctagt gaactcaagg aaatccagct cattcgtgag
    65521 tatgaattga ttatgctcga ctatagtgag gacaagcagg cgcgtttgga acgtgtcatg
    65581 gcagagatgg actctctcca agcttgggaa atcgagagtc aggtcaagac cgttcttagc
    65641 aaattgggca ttcaagactt atctactcct gttggggaat tgtcaggtgg tctgagaaga
    65701 cgggtacagt tggcacaagt cttacttggc aaccacgacc ttttgctttt ggatgagccg
    65761 accaaccatc tggatattgc gattattgag tggctgaccc tctttttgaa aaattctaag
    65821 aagaccgtcc tttttatcac tcacgatcgt tatttcttag acgctttgtc aacacggatt
    65881 ttcgagttgg agcgagcagg cttgacagaa tatcagggca attaccagga ctatgttcgc
    65941 cttaaggcag aacaggacga gcgcgatgca gctctacttc ataaaaaaga acaactctac
    66001 aaacaagaac tggcctggat gcgcagacaa ccgcaggcac gtgcgactaa gcagcaggct
    66061 cgtatcaatc gtttccacga cttgaagaaa gaactttcag gtggcgttgc tgagacagac
    66121 ttaactatga actttgaaac cagtcggatt gggaagaaag tcatcgagtt tcaggatgtt
    66181 tcctttgcct atgaaaacaa gcccattttg caagatttta atctcttggt gcaggccaaa
    66241 gaccgtatcg gaatcgttgg ggacaatggt gttggaaaat caaccctact taacctgatt
    66301 gcaggaagtc ttgagccgac agcaggacaa gttgtgattg gggaaactgt tcgcatcgcc
    66361 tatttctctc agcaaattga gggtttggat gaaagcaaga gagttatcaa ttacttgcag
    66421 gaagtggcag aagaggtcaa gaccagtggc ggttctacga cttcgattgc agagttgctg
    66481 gagcagttcc ttttcccacg ttcgacgcat ggaaccttga ttgagaaatt gtcagggggt
    66541 gagaaaaaac gtctttatct cctcaaactg cttttggaaa aaccaaatgt tcttctttta
    66601 gacgagccaa ccaatgacct agatattgca actttgacag tcttagagaa tttcttgcaa
    66661 ggttttgcag gtcccgtttt aacagtcagt cacgaccgct atttcttgga taaggtagcg
    66721 accaagattc tcgcttttga ggatggcaag attcgtcctt tctttggtca ttacaccgac
    66781 tatcttgatg aaaaagcttt tgaaacagat atggccaatc aagtgcaaaa ggccgaaaag
    66841 gaaaaagtgg tcaaggttcg agaagacaag aaacgcatga cctaccaaga aaagcaggag
    66901 tgggcaagta ttgaaggtga tattgaaacc ttggaaaaac gtatcgctgc tattgaagag
    66961 gaaatgcagg ctaacggctc tgactttggt aagctggcta ctctccaaaa agaattggat
    67021 gagaaaaatg aagcactcct tgaaaaatac gaacgctatg agtatctcag tgaatttgat
    67081 agttaagact attcgaaaat caaagtgcaa actatgtcgg cttcacattg ccgactcaag
    67141 tacagcctgt gaccggcttc ctaatttgca ctttgatttt tattgagtat aaaagaatag
    67201 aaaaatcccg tctcatgaaa ggatttctct attctttttt ggtttcttga tgaaagatat
    67261 tttgccaggt ttcgtggcga cgccagatac tggtatggat gataccatct aactcatagc
    67321 agatgagttt ggttttttga ctgatggaag taatttgaat gtccttgata gcagaattta
    67381 actctttttt ggttttataa gcctctttat ccatctgctc tccatcttgg cgaatataga
    67441 caaaatcatc agtcaagagt tcttctagtt ggtttccttg gtcaatcaat tgttcacgca
    67501 taagcaattt tttatagaca ttgtctaaaa tttcatcctc agggataggt gctggttcga
    67561 tatggacatc ggtatcaaag acgccaaaac gctcctccag catagactcg acctgatccg
    67621 cgatttcatg gctttcaaaa acagacaagt caggattcat ctctagtgta atatccaggt
    67681 agatgttgct accgtaggta cgacctcttt gggacttaac cttgctaatt ttgggaattt
    67741 ccatgatggc cttttggtag tcctcaagca gacggtcgtc gaagccatct gaaaggctaa
    67801 aggaagactc gatgaagata tcataggcag tcttcaagat aaagaaagtg atgatgatag
    67861 caaccagttt gtccacaatg ggataattga aactgctagc taggatggca atggtcgtac
    67921 caagtgaggt aacagcgtca gaaagattgt ccttagcggc agccttcagg gccttggagt
    67981 tggatttctt actgagacga gtattgtaga gatagaccat gaacattatc gatgcagaaa
    68041 tgattcccag agttgcacca agagggtcaa taaccgtttc ttcacgactg agaattttct
    68101 gaatggtatc ccttagaaca tcaaagccaa catagaacat gataatagaa gtgatcaagc
    68161 tagccaaatc ctcaatcttc cagtggccaa aacggtggtc tcggtcagca ggctgtcgtg
    68221 ccatccgaat gccaatcaag agggcaacat ttccaatgat gtccgacacg ttgttaaaac
    68281 catcggccac caaactggat gaatgaagga gatgaccagc tgctaatttg gctgcagaca
    68341 agatcaaata ggtcgaaata ctgataatgg ctccacgctc agctaacttg agatttgaga
    68401 tagattgctt cattcaactt cctttctagt cacatagcat tctaccatta tactggtttt
    68461 caaggaaaaa ttcaaataag gcagttttta ctctttgaaa actccccaaa atttggtata
    68521 atggtactac tcaagggagt agctggcaga aacctgtgat agtgtcgtca ttccgaattt
    68581 tatgctgaaa agtatgcttt ccggccctat cttaaacagc gagacttgtt atgattaaca
    68641 ggtctctttt tgtttgtcgt gaaaagatat gacagaaaga gagtctgttt tgcacacaat
    68701 gtcaaggagg agacacatgt caaaagaaca aaaacgccaa gcgttttata ctcagagccc
    68761 tgaagaggtc ttgcaggcta tggatgcgac cgagcaaggt ttgtcatcaa gtgaggcgga
    68821 aaagcgcctt gccgaatttg ggcacaatga actcgaagaa ggcgagaaac gatcaatctt
    68881 ggtcaaattc atcgagcaat ttaaggattt gatgattatc atcctagttg cggcagcaat
    68941 cttgtcagtc gtgacttctg gtggggaaga tatcgcagat gccattatca tcctagctgt
    69001 ggttatcatc aacgctgcct ttggtgttta ccaagaagga aaagctgaag aagctattga
    69061 agccctcaaa tccatgtcta gtccagttgc ccgcgttctt cgtgatggac acatggcaga
    69121 gattgactct aaagaattgg taccaggcga tatcgttgcc cttgaagcag gtgacgtggt
    69181 accagcggac ctacgtttga tagaagccaa ctctcttaaa attgaagaag cagccttgac
    69241 aggtgaatct gtaccagtcg aaaaagactt gtcagtcgag cttgcgacag atgctggtat
    69301 tggtgaccgt gtcaacatgg ccttccaaaa ctcaaacgta acctatggtc gtgggatggg
    69361 tgttgttgtc aatacaggta tgtacactga agttggtcat attgctggta tgcttcaaga
    69421 tgcggatgag actgatacac cactcaaaca aaatttgaac aacctttcta aggtcttgac
    69481 ctatgctatc ttggtcattg cccttgttac ttttgtagtg ggtgtcttca ttcaagggaa
    69541 aaatccactt ggtgagttgt tgacttctgt tgcccttgcc gttgcagcca ttccagaagg
    69601 acttcctgct atcgttacca tcgttctttc tcttggtact caagttttgg ccaaacgaca
    69661 ttccatcgtt cgtaagttgc cagcagttga aacacttggt tcaactgaaa tcatcgcttc
    69721 tgataagact ggtacgctga ctatgaacaa gatgacagtc gaaaaagtct tctacgatgc
    69781 ggttctacat gactcagctg atgatattga actaggtctt gaaatgccac tacttcgttc
    69841 agttatcttg gccaatgata cgaaaatcga tgtggaaggt aacttgattg gtgacccaac
    69901 cgaaacagcc tttatccaat atgccttgga caagggctat gatgtcaaag gtttcttaga
    69961 gaaatatcct cgtgtagctg aattgccatt tgactctgac cgtaagctca tgtcaacagt
    70021 tcacccattg ccagatggtc gtttccttgt agcagtcaag ggtgcgccag accaactctt
    70081 aaaacgttgt cttcttcgtg ataaggctgg ggatattgct ccgattgatg agaaggttac
    70141 aaatctcatt catacaaaca attctgaaat ggctcatcaa gccttgcgtg tccttgcagg
    70201 tgcttataag attatcgata gtattccaga aaatctcact tctgaagagc ttgaaaatga
    70261 tttaattttt actggtttga ttgggatgat tgatcctgaa cgtcctgaag ctgctgaggc
    70321 tgttcgtgtg gctaaggaag ctggaattcg tccaattatg attacaggtg accaccaaga
    70381 caccgcagaa gctattgcca aacgtttggg aatcattgac gcaaacgata cagaagacca
    70441 cgttttaact ggtgctgagc tcaacgaatt atctgatgaa gactttgaaa aagttgttgg
    70501 tcaatactct gtttatgccc gtgtgtctcc agagcacaag gttcgtatcg tcaaggcttg
    70561 gcaaaaacaa ggtaaggtcg ttgccatgac aggtgacggt gtcaatgatg ccccagctct
    70621 gaaaacagca gacatcggta tcggtatggg aatcactggt acagaggttt ctaagggggc
    70681 ttctgatatg attcttgcag atgataactt tgcgactatt atcgtcgcag tggaagaagg
    70741 acgtaaggtc ttctcaaata ttcaaaagac tattcagtac ctactttctg ccaatactgc
    70801 tgaagtatta accatcttcc tatcaacctt gtttggttgg gacgtcttgc agccagttca
    70861 tcttttgtgg attaacttgg taacggatac cttcccagca attgcactag gtgttgaacc
    70921 tgcggaacct ggtgtcatga atcataaacc acgtggacgc aaggcaagct tcttctcagg
    70981 tggtgttttg agttctatca tttatcaagg tgtactccaa gcagctcttg ttatgagtgt
    71041 ttatggcctt gcgattgctt acccagttca tgtgggtgac aatcatgcta ttcatgcaga
    71101 tgccctaacg atggcctttg caacccttgg tttgattcag ctcttccatg cctacaatgt
    71161 caagtctgtc taccaatcca tcttgacagt tggcccattc aagtctaaga cctttaactg
    71221 gtccatcttg gtatccttta tccttctcat ggcaacaatc gttgtagaac cgcttgaagg
    71281 aatcttccac gtaaccaaac tagacttgtc acaatgggga attgttatgg ctggaagctt
    71341 ctcaatgatt atcatcgtcg aaatcgttaa gtttattcaa cgcaaactcg gttttgacaa
    71401 gaatgcgatt taagggaggt ttcggatgtc agcatatcaa ttaccgaccg tatggcagga
    71461 tgaagctagt aatcaaggag cttttacggg gttaaacaga ccaacagcag gtgcccgttt
    71521 cgaacaaaac ttgccaaaag gagaacaagc ttttcagctt tattcactgg gaacaccaaa
    71581 tggtgtgaag gttactatct tattggaaga attactagaa gctggtttta aggaagcggc
    71641 ttacgacttg tataagattg ctatcatgga tggggatcaa ttcggctcag actttgtgaa
    71701 gctcaatcca aattccaaga ttccagcctt attggaccag tcaggtactg aaaacgtaag
    71761 agtctttgag tctgctcata ttcttcttta ccttgctgag aaatttggag cctttttacc
    71821 aagtaatcct gtggaaaagg tagaagtttt gaattggcta ttctggcaag caggtgcagc
    71881 accttttcta ggtgggggat ttggacattt cttcaattat gctcctgaaa aattggaata
    71941 tcctattaac cgttttacga tggaagtgaa acgccagttg gatttattgg ataaggaatt
    72001 ggctcagaaa ccttatattg caggcaatga ctatacgatt gcagatattg ctatctggtc
    72061 ttggtatgga cagttagttc aaggaaatct ttaccaaggt tctgcaaaat ttttggatgc
    72121 ctcaagttat caaaatctag taaaatgggc agaaaaaatt gccaatcgtc cagctgttaa
    72181 gcgtggattg gaagtaactt atacagaaat taaatagcaa aaaagtcatc ttcggatggc
    72241 tttttgctac agttgaggga aagggtttgc agttatcggc ttttgtgcta taattgctat
    72301 aatatagtaa aaagcaagag gagtgtgagg aagtggaaaa gaaaattgtg aaggatatct
    72361 tatttttatc tcaagtgtct cagccggcaa gtcaggagga cctttatctt gccagagatt
    72421 tgcaggatac actcttagca aatcgtgata cctgtgttgg tctagctgcc aatatgattg
    72481 gggtgcagaa gcgcgtgatt atctttaatc ttggcttggt tcccgtggtc atgtttaacc
    72541 cagtgcttct gtcctttgaa ggatcttatg aggcagaaga aggctgtttg tccttggtag
    72601 gtgtgagatc aactaagcgt tatgaaacca taaggcttgc ctatcgtgac agcaagtggc
    72661 aggaacagac cattaccttg acaggcttcc cagctcagat ttgccagcat gagctggatc
    72721 acttggaagg acgaatcatt taggaggaaa gcaaatgaaa cgaatagtct ttgaacttat
    72781 ttttatcgca acgacctggt atatcttttt accgcccctt aacctgacca gctgggaatt
    72841 tctcttcttc ctctgtgggc atttgttagt tgtggcaatc ttatttggct ttggcaaggg
    72901 gataaacctt gtcaaaacgg ttcatgtgcg ccacggtaag gcggaagctg ccttaaatct
    72961 tgagggtttc aaaatcaatc ggttagggaa aattctgtta gcttcgattg gaggaattct
    73021 tctcttggca gctttggttt ccttggtaac ttccagcatg tttcaggcta aaaattatgc
    73081 caatgtagtc acggttacgg aaaaagactt tactgaattt cctaggagtg acaccagtaa
    73141 ggttcctatc ctagatagaa gtactgctga aaaaattgga gaccgctact tgggttccct
    73201 aaccgataag gtgtcgcaat acgtagcggc agatacctat acccaattga caattgatgg
    73261 gaaaccttat cgggtcacac cactagaata tgcagaccct atcaaatggt ttaacaatca
    73321 agccaaggga atcggtgagt atatcaaggt ggacatggta actggaaatg cggatttggt
    73381 ggacttgaag acaccaatca agtattcaga ctcggagtat tttaaccgtg atgtcaaacg
    73441 tcacctgcgc ttgaagtacc cgactaaaat ctttaaaact ccatcttttg aggtggacga
    73501 tgagggcaat cctttctatg tagcaacggt ttaccaaaag caatttggac ttgcggttcc
    73561 tcgtcctgct tcagtcatta tcttggatgc tacaaatgga gaaaccaagg aatacagctt
    73621 atcagatgtt ccagaatggg tggacagggt ctatccagca gaggaaacca ttgagcaaat
    73681 caactacaac ggcaagtaca aggacggttt cttgaatgcc atgatttcca agaaaaatgt
    73741 gacccagact accaagggct ataattactt gtctatcggt aatgacatct atctctacac
    73801 aggtgtgacg tcggctaatg cggatgagag taatcttggt ttcatccttg aaaatatgcg
    73861 aacaggagaa atcactaagt atagcttggc ttctgcgaca gaagaatcag cccgtgaatc
    73921 agcagaaggt gctgttcagg agaaatccta caaagcaacc ttcccaatcc tcatcaacct
    73981 caatgacaag cctctctaca tcatgggctt aaaggacaat gctggcttgg tcaaagagta
    74041 cgccctggta gacgcagtcg agtaccaaaa tgttatcgtt gctactacag tggaagagat
    74101 gctcagcaag tatgccaata aaaacgacct tgaaattgac aatgcaacga cagaaagcat
    74161 caagggagta gtagcagacc tcaaatcagc tgttatcaag ggagacactg tctacttctt
    74221 taaagttgat ggcaagatat acaaggtcaa ggcttcagta tccgatgacc ttccttacct
    74281 tgaaaatggt aaaaccttcg aaggtcaagt aggaaaagac aattatctca agacctttaa
    74341 agtacaataa tactcttcga aaatctctag ctctatctgc aacctcaaaa cagtgttttg
    74401 agcagcctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat aaaaaaggtt
    74461 tatttaataa atatatgtta taataaggta aattaagcct aatggaggac aaagaaatgg
    74521 gtttttattt gatggttgct tcaatgctac tcggactgct cgctttgaag ataggttttt
    74581 ctcagttcaa ggagaaaaaa gataaattct tatctatctt aacaagttta gctggcacag
    74641 cccttgttct cgtggctgtc tggttaggat ggcccaaata aatagaaaaa cctcggtcaa
    74701 accgaggttt ttcaaatgaa tttcttggtt gtggctaaaa aatatgctac actatcaata
    74761 tgaaaatttt aatcccaaca gcaaaagaaa tgaacacaga cttgccaagt atcgaggcaa
    74821 ttcctttaaa accagaaagt cagaccgtgc ttgatgcctt ggctctctat tctgccagtc
    74881 aattggagag tttctacaag gtatcggctg agaaagcggc ggaagaattt caaaatatcc
    74941 aagctttgaa aaggcaaact gctcaacact atccagcctt gaaacttttt gatgggctta
    75001 tgtaccgcaa cattaagaga gataagctga ccgaggcgga acaagattat cttgaaaatc
    75061 atgtcttcat tacctcggct ttgtacggtg ttgttccagc cttgtcaccc atggctcctc
    75121 accgtttgga ttttttgatg aaattaaaag tcgctggtaa gactttgaag agccattgga
    75181 aggcagtcta tgatgaagct ctgaagaagg aagaagtgat tttctctctc ttgtcatcag
    75241 agtttgagac tgtattttct aaggaaatca gagcaaagat ggtgaccttc aaattcatgg
    75301 aggatagagg cggtcagctg aagattcact caactatctc caagaaagcg cgcggggcct
    75361 ttctaacagc tttaatagaa aatcaagtac aaactgtggg ggaagcacgt cgcttgaact
    75421 ttgctggatt tgtttaccga gaagatttgt cacaaccaca gggattggtt tttgtaaagg
    75481 aagtatagaa atcagatatt ttgtatttgg caatatgtat catcagctgt tttagtttat
    75541 aaatgagaaa aaaagcgaac aagctagtct tctgagtgtc agaaaagtag tcttgttcgc
    75601 ttttattatg ttatactctt cgaaaatctc ttcaagccac gtcagcgtcg ccttaccgta
    75661 tatatgtcac tgacttcgtc agttctatct acaacctcaa agcagtgctt tgagcagctt
    75721 gcggctagct tcctagtttg ctttttgatt tttattgagt gttagttact tgatagcttc
    75781 gaccaagtct tgagcttgtt tttcaagtga gtttaggact gtttcttcaa gaaccaattt
    75841 tccgtctgcc caggcagagt cattaacacg tgcagcagtg aaatcaccaa cgccttgtgt
    75901 acggataaat ggcaagaggt ctttgtagat agcgaaaagt tgatcgtgcc ctgcattggc
    75961 tacagatgat actgtgacaa acttgtcttg aagggcagaa acgccacgtg tatcagacaa
    76021 gtcaagggca cgagatagcc agtcaagcaa gtttttcact gtaccaggga tagagaagtt
    76081 gtagactgga gagaaaatcc agatagcatc cgcaacgaga actgcttcac gagcagcagc
    76141 tacagctgga tgtgttggaa cttccaaatc ttggctgaag agaggaaggg ctgaataatc
    76201 aaggtagcta acttccgctt taccagcaag agctttctca gcttcgagcg ccatttggtg
    76261 gttgaaagaa ccttgacgta gtgatccgac gataaataat acttttttag acatgatgtg
    76321 tctccttttt cttaaaattt cgagaactct ctcgttgtta taaaatatat tacaacaaaa
    76381 caaaagaact tgcaagaaat ttgctcagag tttatttgaa aattgtaaaa tttcggaaac
    76441 tctagtcatt tgtgactgaa aaagtaagaa ctgtttcact ttcaaaatcg gttttgtttg
    76501 aagggagaaa tagaattggt tgctcaaagc acagctttga ggttgcagat aaagctgacg
    76561 tggtttgaag agattttcga agagtattct tatattcact tgtaataaag cttaatagat
    76621 ggtaaaatag acgagtgaaa aaaagacaaa acaaagcaaa aaataatcta ctgtggcagt
    76681 atggtctagg gatgacgatt ttgtttgtgg ttatcagtgc ttcctttctg tatatggttt
    76741 ctcttagcat gaaaccctat caaacagcta aaagtgaagg agaaaaatta gctcagcagt
    76801 atgcaggatt agagaaggct gatcaggttg atttatacaa tggcttggaa tcttattaca
    76861 gcgttcttgg tcgtaataaa cagcaagaag cgcttgctgt cctgattggt aaagatgacc
    76921 ataagattta cgtttatcag ctaaatcagg gtatttcaca agaaaaagca gaaacggttt
    76981 ctaaggaaaa gggagctggc gagattgaca agataacctt tggtcgttat caagacaagc
    77041 caatctggga agttaagtca ggatctgatt tttatctagt agattttgaa acaggagcat
    77101 tggtcaataa ggagggccta tgaaactatc caaccgtgtt ttagaaatgg aagaaagtgt
    77161 gactttggct gctggagccc gtgccaaagc actgaaggct gagggtagag atattttgtc
    77221 tctaaccttg ggtgagccag atttcactac tcccaaaaat atccaagatg ccgccattgc
    77281 atcgattcga gatgggcgtg cttcttttta tacagtaacc tcaggtctgc cagagcttaa
    77341 ggcggtggtc aatagctact ttgagcgctt ttacggctat tctgtagcgt caaatcaagt
    77401 gacagtcgct gcgggagcca aatattctct ctataccttc tttatggctg tggtcaatcc
    77461 aggtgatgaa gtcatcatcc caaccccata ctgggttagc tatggagatc aggtcaagat
    77521 ggcagaaggc gttcccgtct ttgtttctgc taaggaagac aatcacttta aggtgaccgt
    77581 agagcagtta gaagcagctc gcactgacaa gaccaaggtt ttggtgctga attcgccatc
    77641 taatcccaca ggtatgattt acacccgtga ggaactcttg gcaattggaa actgggctgt
    77701 agaaaatgat attctcatcc tagcagatga tatctatggc cgcttggttt ataatggtca
    77761 tgagttcaca ccgatttcta gcctatcgga agcgattcgc aagcaaacag tggtcatcaa
    77821 tggtgtgtct aaaacctatg ccatgactgg ttggcggatt ggttatgccg ttggagaagc
    77881 agacattatc gctgccatgt ccaagattgc aggtcaaaca acttcgaatc cgtcagcagt
    77941 agcccaatat gcagcagttg aggctctatc aggtgagcaa gatactgtag aaagcatgcg
    78001 tcaggccttt gaggaacgtc ttaataccat ctatcccctc cttgcagagg tgccaggatt
    78061 tgaagtggtc aaaccacaag gggccttcta tctcttccca aatgtcaaaa aggccatgga
    78121 gatgaaaggc tacacggatg tgacagactt tacaactgct atcttagaag aagccgaagt
    78181 ggccttggta acaggagctg gatttggagc accagaaaat gtccgcctca gctatgcgac
    78241 agacctagac acgcttaaag aagcagtcga acgcttgaaa gcatttatgg gtagtgagaa
    78301 tgattgatca ttttgagatt aaggtaaagg atttacaaat ttcagaagga ttttatagga
    78361 gttttctcgc tcctttggac tataaattgg cttttaagac tagttctcta attagttttc
    78421 tatccccgaa cagccctcat cctggtggtg atttttggct gactcaggga acacaagatc
    78481 ctgttcattt tgctttttta gcagaaaata aggaagaagt tcaggcttgt tatgaggctg
    78541 gcttagaggc aggtgggcga gacaatgggg ttcctggtta tcgaagtgag catccgattt
    78601 attatgctgc ttttatgatt gacctggatg ggaacaatat agaggtggtt tgccataaag
    78661 aataaaaaag aaaaggaaaa ataatgacaa aacgtgtaac gattattgat gtaaaagact
    78721 atgttggtca ggaagtgacg attggcgctt gggttgccaa caaatcagga aaagggaaaa
    78781 tcgctttctt acaattgcgt gatggaacag ccttctttca aggtgtggct tttaaaccaa
    78841 actttgtcga aaaatttggt gaagaagtgg gacttgagaa gtttgatgtt atcaaacgct
    78901 tgagccaaga aacgtctgtt tatgtgacag gtattgtcaa agaggacgaa cgttctaaat
    78961 ttggctatga gttggacatc acagacatcg aagtgatcgg tgaatctcaa gactacccaa
    79021 tcacaccaaa agaacacgga acagactttt tgatggataa ccgtcacttg tggctacgct
    79081 ctcgtaagca agtagctgtg ttgcaaatcc gtaacgctat tatctatgca acttatgagt
    79141 tctttgacaa gaatggtttt atgaagtttg acagcccaat tctttcagga aatgcggcag
    79201 aagattctac agaactcttt gaaactgact acttcggaac gccagcctac ttgagccaat
    79261 caggtcagct ttacctagaa gcaggggcta tggctcttgg tcgtgtcttt gactttggtc
    79321 cagttttccg tgctgaaaaa tcaaaaacac gccgtcactt gactgagttc tggatgatgg
    79381 atgctgagta ctcatacttg acacatgatg agtcgcttga cttgcaagaa gcttatgtga
    79441 aagctcttct acaaggtgtt cttgaccgcg cgcctcaagc cttggaaacc ttggaacgtg
    79501 atacagaact cttgaaacgc tacattgcag agccattcaa acgtatcact tacgatcaag
    79561 ccattgacct cttgcaagag catgaaaatg atgaagatgc tgactacgag catcttgagc
    79621 atggtgatga ctttgggtca ccacacgaaa cttggatttc aaaccacttt ggtgtgccaa
    79681 catttgtcat gaactatcca gcagccatca aggccttcta catgaaacca gttcctggaa
    79741 atccagagcg cgtgctttgt gcagacttgc ttgctccaga aggctatgga gaaattatcg
    79801 gtgggtctat gcgtgaggaa gattacgatg cccttgtcgc taagatggat gaacttggca
    79861 tggatcgtac agaatatgaa ttctaccttg accttcgtaa atacggtaca gttccacacg
    79921 gaggatttgg tatcggtatc gaacgtatgg taaccttcgc agcaggaaca aaacatatcc
    79981 gtgaagctat tccattccca cgtatgttgc accgtatcaa accataagaa caggaaaacg
    80041 cccatgtggc gttttttcga attctagtgt ttttacttgc gtaaaaaaat tttttctagt
    80101 ataatagttt attgtgagcg aacctcactt accccttgca aagtcttggg gtcattagac
    80161 caaaaggagg aacatatcaa tggctaaata cgaaattctt tatatcattc gtccaaacat
    80221 tgaagaagaa gctaaaaacg ctttggtagc acgttttgac tctattttga ctgacaacgg
    80281 tgcaactgtt gttgaatcaa aaacttggga aaaacgtcgt cttgcatacg aaatccaaga
    80341 tttccgtgaa ggactttacc acatcgttaa cgttgaagca aatgacgatg cagctcttaa
    80401 agagtttgac cgtctttcaa aaatcaatgc tgacattctt cgtcacatga tcgtcaaaat
    80461 tgacgcgtaa gaaggtaaac tatgattaac aatgttgtac ttgtagggcg tatgacacgt
    80521 gacgctgagt tgcgttatac cccatcaaat gtagcagttg cgacttttac tcttgcagta
    80581 aaccgtacat ttaagagtca aaatggtgaa cgtgaggctg attttatcaa tgtcgttatg
    80641 tggcgccaac aggctgaaaa tcttgctaac tgggctaaaa aaggctcact tatcggggtg
    80701 acaggtcgta tccagactcg tagttacgat aaccagcaag gacaacgtgt ctacgtgaca
    80761 gaggtcgtgg ctgagaattt ccaaatgttg gaaagccgta gtgtgcgtga gggtcacaca
    80821 ggtggagctt actctgcacc aactgcaaac tattcagcac ctacaaattc agtaccagac
    80881 ttttcacgta atgaaaatcc atttggagca acaaacccat tggatatttc agatgatgat
    80941 ttaccattct aatggacaac taaacttata aaggagaaaa aacatggctc aacaacgtcg
    81001 tggcggattc aaacgccgta aaaaagttga ttacatcgca gcaaacaaaa ttgaatatgt
    81061 tgattacaaa gatactgagc ttcttagccg tttcgtttca gaacgtggga aaatccttcc
    81121 tcgtcgtgta acaggaactt cagctaaaaa ccaacgtaaa gtaacaacag ctatcaaacg
    81181 cgctcgcgta atggctttga tgcctttcgt aaacgaagat taaagaaaag acccggttgg
    81241 gtctcttttt catgagcttg aaaacaagaa agcgaattaa gaccccaacg ggtctttttt
    81301 cacaagcttt gaaatgagag agcgagttag gctcagtggc tcccttttta cgagtttgaa
    81361 aacaagagaa cacattaaaa gcacgatgga gctttttcat aaatatgtct cttttctcat
    81421 ccaagaaatt aaaataaaaa tgataaactt tttgaaaata ggggatttgc ctactttatg
    81481 atataatgga aagagttaga ttgaaagagg tagtgagatg gacgcgaaat taagatacaa
    81541 ggcaaagaag atcaagattg tcttttttga tattgatgat acattgcgga attcaaagac
    81601 agggtttatt ccaactacaa ttcccactgt ttttaaacag ttgcgtgaaa aaggaatttt
    81661 aataggaatc gcctctggac gtggcatttt tggtgttgtt ccagagattc gtgatctcaa
    81721 gcctgacttt tttgtaactt tgaatggagc ttatatcgaa gataaaaaag gtcaggtcat
    81781 ttatcagcat cagattgaaa agtcagatgt tgaggagtat atctcttggg ctaagcaaga
    81841 aggaattgag tatggcttgg ttgggagtca tgatgccaag ttgtcgactc gcaccgatat
    81901 gatgagtgaa gctatcaatc caatttatcc cgacttagat gtagatcccg atttccatga
    81961 aaaagaagat atctatcaga tgtggacttt tgaagataag ggagatgact tgcacttgcc
    82021 tgacagtctc tcagacaaac ttcgcatggt tcgttggcat caacattcgt ctgatattgt
    82081 gccgatttca ggctccaaag caacgggggt ggaaaaggtt gtggaacacc ttggcttgaa
    82141 accagagaag gtcatggttt ttggagatgg tctcaatgac ttggaactct ttgattatgc
    82201 tggaatcagc gttgccatgg gaatttctca tgataaaatc aaagaaaaag cagattatat
    82261 tacaaaaaca ttagaagaag atggcatttt tgatgcctta gaagtatttg gtatggtaga
    82321 aaaagaattg cattttccac aagtagacat tgaaacagta gaaggtcctc ttgcgactat
    82381 taagaccaat cacggagact tacgtatcaa gcttttccct gaacatgctc ctaaaacagt
    82441 ggctaacttt gtatctcttt caaaagatgg ctactatgat ggtgtcattt tccaccgtat
    82501 tatcaaggac tttatgatcc aaggtggaga cccaactgga actggtatgg gtggcgagtc
    82561 aatctacggc gaatcttttg aggatgaatt ctcagaagag ctttacaata tccgtggtgc
    82621 tctttccatg gcaaatgctg gtccaaatac caacggcagc cagttcttta tcgtgcaaaa
    82681 ccaacaccta ccttattcga agaaagaaat tactcgtggt ggttggccag aaccgattgc
    82741 agaaatctat gccaatcaag gtgggacacc tcacctagac cgccgtcaca cggtttttgg
    82801 tcagttagct gatgaagcat cttacgctgt cttggatgcc attgctgctg ttgagacagg
    82861 agctatggac aagccagttg aagatgttgt aattgaaact attgaaatcg aggactaaga
    82921 tgaaaatcgg tgataagcta aaggggcgta ttacagggat tcagccctac ggtgcctttg
    82981 ttgagttaga gacgggtgat acggggctga ttcacatttc agaaattcgg acaggattta
    83041 ttgaaaatat tcatgaaacc ttgaaagtcg atgaagaggt tcaagttcag gtagtggatt
    83101 tagatgaatt tacggggaaa gccagtcttt ctatccgcac tttggaggaa gaaaagtacc
    83161 agtttcctag acggagacgc ttttcaagcg accgctttaa ctacggtttt gctccctttc
    83221 gacgaatgtt accaatctgg actggagaag ccctgcacca tttaaaaaag aagaagtagt
    83281 ttagagtttt atattttttg taatgttaat ataaatttgc tataatagga ccatggaaga
    83341 agaacaatta ttaaaatcag gagagcgcat taaccagctc ttttcgacag atatcaaaat
    83401 cattcaaaat agagaggttt ttagctattc ggtggatagt gttctcttat cacgatttcc
    83461 acgttttcct aagaaggggt tgattgtgga tttctgtgct gggaatggag cagtggggct
    83521 ttttgctagc actcgtactc aagcacagat attgtctgtt gagattcagg agcgtttggc
    83581 ggatatggct gaacgctctg tccgtttgaa tggattagag gagcaaatgc aggtcatctg
    83641 cgatgatttg aaaaatatgc ctgctcacat tcaggggagt aaggtggata tgattttgtg
    83701 taatccaccc tatttcaagg tggatcctta ttctaatctg aacgagagtg aacattatct
    83761 cttggctcga cacgaaatca cgactaattt ggaagaaatc tgtcgtagtg ctcagagtat
    83821 tctcaagtct aatgggcgtt tggccatggt tcatcgtcct gatcgacttc tggatatttt
    83881 ggatacgtta aaacgacata atctagcccc taagcgcctg cagtttgttt atccaaaaag
    83941 agaaaaggaa gccaatatgc ttttgattga ggcgatcaag gatggctcaa caagtggctt
    84001 taaggtctta cctcctttga ttgtccacaa tgatgatggc tcttatacgc ccgaaatcga
    84061 agagatttat tatggatcat aaggcttata tgtacgttct ggagtgtcgt gatggatcct
    84121 actatatagg ctatacgact gatgtgagaa gacgcctcgc tatccacaat agtgggaggg
    84181 gagccaaata tacacgagca cgcttgccag tcaaacttat ctatgctcaa ggttttgcca
    84241 gtaaggaaga agccatgtcg gctgaagctc ttctcaagcg taagaagagg ccacagaagg
    84301 aagaattttt atctgaaaat caagatagaa atttactcag ttattttgaa gaatcgtggg
    84361 gagtcctttg actcctctta cctttgtcaa aaagcgaaaa aaatgctaca ataaagaaaa
    84421 taaacaaaat gaggtattat catgtccaag attctagtat ttggtcacca aaatccagac
    84481 tcagatgcca tcgggtcatc tgtagctttt gcctaccttg caaaagaagc ttacggtttg
    84541 gatacggaag ctgttgccct tggaactcca aatgaagaaa cagcctttgt cttgaactat
    84601 tttggtgtgg aagcaccacg tgttatcact tctgccaaag cagagggggc agagcaagtt
    84661 atcttgactg accacaatga attccaacaa tctgtatcag atatcgctga agtagaagtt
    84721 tacggtgttg tagaccacca ccgtgtggct aactttgaaa ctgcaagccc actttacatg
    84781 cgtttggagc cagttggatc agcgtcttca atcgtttacc gtatgttcaa agaacatggt
    84841 gtagctgtgc ctaaagagat tgcaggtttg atgctttcag gtttgatttc agataccctt
    84901 cttttgaaat caccaacaac acacccaaca gataaaatca ttgctcctga attggctgaa
    84961 ttggctggtg tgaacttgga agaatatggt ttggcaatgt tgaaagctgg taccaacttg
    85021 gctagcaaat ctgctgaaga attgattgac atcgatgcta aaacttttga actcaacgga
    85081 aataatgtcc gtgttgccca agtgaacaca gttgacatcg ctgaagtttt ggaacgccaa
    85141 gcagaaattg aagctgcaat gcaagctgcc aacgaatcaa acggctactc tgactttgtc
    85201 ttgatgatta cagatatcgt caactcaaac tcagaaatct tggctcttgg tgccaatatg
    85261 gacaaggtcg aagcggcttt caacttcaaa cttgaaaaca atcatgcctt ccttgctggt
    85321 gccgtttcac gtaagaaaca agtggtacct caattgactg aaagctttaa tgcgtaagat
    85381 tttgggtgtc agctcaaaat cggaaagtct agtttgcctt atatcgaaag gagtttcggc
    85441 tccttttttc taggagtgaa gtatgttaga aaatggcgat ttgatttttg tgagagatgg
    85501 gtcagacatg ggacaggcca tccagacttc cacaggtaac tatagccatg ttgccattta
    85561 tttggatggg atgatttatc atgctagtgg acaggctggt gttgtctgtc aagaaccggc
    85621 agacttcttt gagtccaatc atttatacga cctctatgtt tacccagaaa tggatatcca
    85681 gtcggtgaag gaaagagctt gcaaacatct tggagcaccc tacaatgctt ctttctatcc
    85741 agatgcagct ggtttctact gctcccagta tatagcagaa atcctaccta tttttgaaac
    85801 tattcctatg aaatttggag atggggagca ggagattagt gatttttgga gggagtatta
    85861 catagaacta ggtctgcctg ttcctctgaa ccaagctggt accaatccta gtcagttggc
    85921 agcatcgcct ctgttacaat gtaaagaaag gaatcttcat gattcagatt tttaatccat
    85981 ctcgtttgac gagacagcca tttttggaga attgatccgc tatctggacc agtatgagga
    86041 tgtgattcta cgggaaatta aggctcaatt tccagatgtt gcagttgata aactcatgga
    86101 agagtatata aaggcaggct tgattctacg tgaaaataag cgctattacc tcaattttcc
    86161 tacgcttgaa tcacttgata gtcttgaact ggatcaagag atttttgtca gagaagctag
    86221 tccggtctat caagccttgt tggagcagag ttttgagacg gaattgcgca atcaaatcaa
    86281 tgcagctatt ttagttgaaa agacggactt tgcgcgcatt aaaatgaccc tgtccaatta
    86341 tttttacaag gtcaaacagc agtatccttt gacagaaaaa cagcaggagc tctatgacat
    86401 tttaggagat gttaatcctg agtatgccct caagtatatg acggcttttt tgttgaaatt
    86461 tctcaaaaaa taccagctta tgcagaaatg ccgtgatatc tttgtggaca gtttggttgt
    86521 cttaggctat attgtgcaaa atgaagatgg aaagtatgag ttggctatcg attttgataa
    86581 ggagagatta actttctact tagcgtgatt tcttgtttct gagcacattg tttgactttc
    86641 cttagtattc ggtataaact atatgtaacc ggtaacacat atcggaataa actaaaggag
    86701 acaatcatat gtcacttgaa aacaaattgg aacaagcaac aggcgctgtc aaagaaggtt
    86761 ttggtaaagt tactggagac agcaagacag aacttgaagg agctgttgaa aaaacagttg
    86821 ctaaggcaaa agacgttgta gaagacgcaa aaggtgctgt agaaggtgcc gttgaaggtt
    86881 tgaaaaacgt ttttactaaa gaataggaaa aaatcaaggg tttcattttc ccttgatttt
    86941 ttctattctt ataaataatt ttctgcgacg gctgtatctc ctgggtagga ttctttcttg
    87001 ccctggatga tttggtaaca atcggctccc ttacccgcaa taataactgc atctaattcg
    87061 tgatttgtga tagccattgc cgccttgatg gcttcttggc gatccgcaat cttttcaaca
    87121 ggatgattga tgtagttact aatttcatct gcaatggcca ttgggtcttc atagttaggg
    87181 tcatcagcag tcagaaagac ttgaatctca gggtgttgat tgaggaggag gccaaagtcc
    87241 ttacgacgac tttctccctt gtttcctgtt gatcccagaa ccagagcaat ctttccggtt
    87301 tgatgagttt caaccacatt gatgagtttt ttcagactat ccccattgtg ggcatagtcg
    87361 atgaagacct tggctccatt tttctgagtg aggacttcca tacgaccagg aacgcgggtt
    87421 gcagcgatgc cttttttgat gtcctcaaga cttgctccga gacggagaca agcaagtcca
    87481 gcagcaactg cattttcttg gttgaagttg ccaatgagtt ggatatcata atctccagcg
    87541 agtttacccg tagctgaaaa gctaaaggct ttggaattct cgatttggtt atcaaattgg
    87601 ctaccataga aatcatggtc ttgatcttca acctgttctc tcaagactga gaagtggtcc
    87661 atgtcactgt taatgatgac tgctcggcta ttttccatca agagacgctt gtggtagaaa
    87721 tagtcttcaa agctagggtg ttcaatcggg ccgatatggt ctgggctgat atttaggaaa
    87781 actcccacat caaaggtcag tccatagact cgatggacta gataggcttg actggagact
    87841 tccatgatga ggtgagtacg gtcattttgc acagcctgat tcatcatgtc aaagaggtca
    87901 atactctcag gggttgtcaa cgctgactta aagaaagtct cgccatcaag agttgtgttc
    87961 atggtcgaca acatagcagg tctatgccct tgagataaga tgttataggc gaaataggtt
    88021 gctgttgtct tacccttagt accagtaaag gcaaggagtt tgagtttctc ttgtggatta
    88081 ccatagaact ccatggcaat caaactcatg gctttcttta tatcgttcac aatgatgaca
    88141 gggatatcga cttcgtagtc cttttcagct acataccaag ctaaaccttg tgttatagca
    88201 gaaagaaggt attctttttt aaaggcagcg ccttttgcaa aaaaaagagt gtcttctgtt
    88261 acttttcggc tgtcgtagct gatgctatca aaaataactt tgctgtagtt gtagtggtaa
    88321 tgaccttggt caataatttc gcgaaaaagg ccatctttct ttaaaatatc taatacggtt
    88381 tcaatcttaa tcatactttc tattgtaaac cgaaagtcgt aaatttacaa gtaacaagga
    88441 aaagtttata atggaagata aggagttttt cctagttatc aaaattgaat gaggaatcta
    88501 tgtcgcacga aaacaatcac cagcaggccc agatgttacg ggggactgct tggctaacgg
    88561 ctagtaactt tatcagtcgc ctactcgggg ctgtttacat tatcccttgg tacatctgga
    88621 tgggggctta tgcagctaag gcaaatggtc tctttaccat gggttacaat atctatgctt
    88681 ggttcttgtt ggtttcaaca gcggggattc cagttgcggt ggccaagcaa gttgccaagt
    88741 ataataccat gcgagaagaa gagcatagct ttgccctgat tcggagcttc ttaggcttta
    88801 tgacaggact aggcctggtt tttgctttag tcttgtatgt ctttgctcct tggctagcag
    88861 acttgtctgg cgtgggcaaa gacttgatcc caatcatgca aagcttggct tggggagtct
    88921 tgattttccc gtctatgagt gttatccgag gatttttcca agggatgaat aacctcaaac
    88981 cctatgccat gagccaaatt gctgagcagg tcattcgtgt tatctggatg ctcctagcaa
    89041 cctttatcat tatgaagctc ggttcaggag attatctagc agccgttacc caatcaacct
    89101 ttgctgcctt tgtcggtatg gtagccagtt ttgcagtctt gatttatttc cttgcccaag
    89161 aaggttcact caaaagagtc tttgaaacag gagataagat taacagtaag cgtctcttgg
    89221 ttgataccat taaggaagcc attcctttta tcctgacagg gtctgccatc cagctcttcc
    89281 agattttgga tcagctgacc tttatcaata gtatgagctg gtttaccaac tacagcaatg
    89341 aggacttggt tgtcatgttt tcttatttct cagccaatcc taataaaatc acgatgattt
    89401 tgatttctgt aggggtttcg attgggagtg ttggtttgcc acttttgacg gaaaactatg
    89461 tcaaggggga cttgaaagcg gcttctcgtc tcgttcagga cagtctcacc ctactcttta
    89521 tgttcttgct accagcaacg gttggagtgg ttatggtagg agaacctctt tatacggtct
    89581 tctatggtaa gccagatagt ttggctctgg gcttatttgt ctttgcagtt ttgcagtcta
    89641 ttattttagg cttgtacatg gtcttgtctc caatgcttca ggccatgttc cgcaaccgca
    89701 aggccgttct ctattttatc tatggttcta ttgccaagct agtcttgcaa ctacctacca
    89761 tcgccctctt ccacagttat ggtcctttga tttcaacaac cattgctctc atcattccta
    89821 acgtcttgat gtatcgggat atttgtaaag taactggtgt caagcgcaag gtgattttga
    89881 agcgaaccat tttaatcagt ttgctgaccc tagtcatgtt tctgttaata ggaaccatcc
    89941 agtggctgtt aggatttttc ttccaaccaa gtggacgttt gtggagcttc ttttatgtag
    90001 ctcttgtcgg tgccatgggg ggtggacttt atatggttat gagtctgcgt acctatttat
    90061 tagataaggt aataggaaaa gcccaagcag atcgcctgcg agcaaaattt aagctttcgt
    90121 aaggtagcat ttataaataa aaggaataag ttgaacaatc ttttaggaga acttgaaact
    90181 tattcctttt ttagcgtcaa aatagctaaa attatctttc aaaaatagaa aatgaggttt
    90241 ttttgatttt ttggaaaaaa caattgacta aacaaaccaa gagttgtata ataaaacaaa
    90301 tatttaaagc aggaggttct ggaaatgaaa aagtctaaga gcaaatatct aaccttggca
    90361 ggtcttgtcc tgggtacagg agttttattg agcgcgtgtg gaaattctag cactgcatca
    90421 aaaacctata actatgttta ttcaagtgat ccatctagtt tgaactatct agcagaaaac
    90481 cgcgcagcaa catccgatat tgttgcaaat ttggtagacg ggttattaga aaatgaccaa
    90541 tatgggaata ttattccatc attagcagag gattggactg tttctcagga cggtttgacc
    90601 tatacctaca aacttcgtaa ggatgccaag tggtttactt ctgagggaga agaatatgcg
    90661 cctgtaactg cccaggattt tgtgacaggt ttgcaatatg cagctgataa aaaatcagaa
    90721 gctttgtatc tagtgcagga ctctgttgct ggtttggatg actatatcac tggtaaaaca
    90781 agcgactttt caactgtcgg tgtcaaggca cttgatgacc aaacggttca atatactttg
    90841 gttaaaccag aactttactg gaattcaaaa acacttgcaa cgatactttt tcctgttaat
    90901 gcagatttcc tgaaatcaaa aggggatgat tttgggaagg cggatccatc tagtattttg
    90961 tacaatggac ctttcttgat gaaagcactt gtctcaaaat ctgctattga atataagaaa
    91021 aaccctaatt actgggatgc taagaatgtc tttgtagacg atgtgaaatt gacctactat
    91081 gatggtagcg accaagaatc actggaacgt aattttacag ctggtgctta tactacggct
    91141 cgtctttttc ctaacagctc cagctatgaa gggattaaag aaaaatacaa aaacaatatc
    91201 atctatagta tgcaaaattc aacttcatat ttctttaatt ttaacctaga taggaagtct
    91261 tacaattata cttctaaaac aagtgacatt gaaaagaaat cgacccagga agcagttctc
    91321 aataaaaact tccgtcaggc tatcaatttt gcttttgaca gaacatctta tggggctcag
    91381 tctgaaggga aagaaggtgc aacaaagatt ttgcgtaacc tagtggttcc tccaaacttt
    91441 gtcagtatca agggaaaaga ctttggtgaa gttgtagcct ctaagatggt caactatggt
    91501 aaggaatggc aaggtatcaa ctttgcggat ggtcaagacc cttactacaa tcctgagaaa
    91561 gccaaggcta agtttgcgga agctaagaaa gaactcgaag caaagggtgt tcaattccca
    91621 atccacttgg ataagactgt ggaagtaaca gataaagtag gcatacaagg agttagttct
    91681 atcaaacaat taattgaatc tgttttaggt tctgataatg tagtgattga cattcagcaa
    91741 ttaacatcag atgagtttga cagttcaggc tactttgctc aaacagctgc tcagaaagac
    91801 tatgatttat atcatggcgg ttggggacct gattatcaag acccgtcaac ctatctcgat
    91861 atttttaata ctaatagtgg aggagttcta caaaatcttg gactagagcc tggagaagcc
    91921 aatgacaagg ctaaggcagt tggactggat gtctatactc aaatgttgga agaagctaat
    91981 aaagagcaag atccagccaa acgttatgag aaatatgctg atattcaagc ttggttgatt
    92041 gatagttctt tagttcttcc aagtgtttcg cgtgggggaa caccatcatt gagaagaacc
    92101 gtaccatttg ctgctgccta tggtttaacc ggtacaaaag gggttgaatc atataaatac
    92161 ctcaaagtac aagataagat tgtcacaaca gacgaatatg caaaagccag agaaaaatgg
    92221 ttgaaagaaa aagaagaatc caataaaaaa gcccaagaag aattggcaaa acatgtcaaa
    92281 taaaatctaa ttgtagataa gtttgtgtaa gaagtctttg tgcttaaaaa cgcataatat
    92341 caggtatata aaatcctaga tgttatgcgt tttgttatag gaagatttat tagattttat
    92401 cctcaaattg agttattccc gactttatcc gttgaaatat tataaggagt atttatgaaa
    92461 ttaaaattat taagagtaga tactaaggtg attatgggga gtttcttact tgttctgtct
    92521 agtctacttg ctttgttgct tccccttatc ttaaagggtt taatagatgg gagttctatt
    92581 gaaaatatag gttccaaagt atttcaatcg tattggtcaa gccttgtttt cttctattgg
    92641 ttactatctg tttagtcaat cgggtgaaaa aagatagcaa aaatcaggaa aaaagtgata
    92701 gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg ggagttgact
    92761 tctgccattg tcaatgacat gagtgtcatt cgtgagtttt taattacgac tttcccaaat
    92821 attattctga gtttagttat ggtacttggt tccattgtag tcttatttag tcttgattgg
    92881 aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat cttgcccctt
    92941 tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatttaaca gggcaattga
    93001 ctgaaaagat tcaagaacat gaattaatta agactaacca agcagagaaa agtgtacagg
    93061 atgttttgga taattgtatt gaaagggtac aaaacaattc actgaaatca gatagggtta
    93121 cttcttttga gaccccgttt gctctcttat ttatctttgc gactatagct gtgatgctaa
    93181 cctatggggg ttatcgggtc agcgcaggat atatatctgt gggaaccttg gtttcgtttt
    93241 tgatttacct ctttcaatta cttaatccta ttagtaatat agctaatttt gtaactgttt
    93301 attctaggag caagggatct tcagttgcac tggataactt gcttgcagtt cctaaagaaa
    93361 aatttgaggg aggaaaatcg gtatcaggac aagggttgaa ttttaaccat gtctattttg
    93421 gttatgatga aaatcgacct gtcttaaagg atattacttg ttcaattttc aaggggcaaa
    93481 aattgctttt gttggaccat ctggatcagg aaaatcaacg attgtgcgtt tgttagagcg
    93541 gttttataaa ccgctttcag gagatattct aatggagcaa tcaagtatat atgattttaa
    93601 cttaaaagaa tggagaagta aaatcgcttg ggtttcacaa aataatgcag tcttatctgg
    93661 cagtattcgt gacaatcttt gtctcggttt gaatcgctta gtaactgatg atgaattgat
    93721 gaaagtgcta gacttagtat cactaggtga tgagattcgc tccatgaaag agggactaga
    93781 tactgaagtt ggtgaacgcg gacgattctt gtcagggggg caaagccaaa gacttcaaat
    93841 agctagaacc tacttaaaag atgctgaaat tcttatattt gatgaagcta ctgctaatct
    93901 tgatgcggat tctgagtatg cgattatcag tagcctctat tctgtattaa aggagaagac
    93961 ggttgtgatt atagcgcata gtttgtcaac ggtaaaagat gtggattgta ttttcttctt
    94021 agaggagggg aaaatcactg gctcaggaac tcataaggaa ctactggaaa atcatgagcg
    94081 ttatgctcgt tttgtgcagg agcaaatgat agagtgaagt gtcttttgag attcaccatt
    94141 ttatagtcta ttaaagggag caggaaaaac tcccttttta tatagtttga aactataact
    94201 agctcttgaa aagaagaaaa tgagttgatg aaaataagtg gtacaatagt tactatagat
    94261 ttggaggtat tgtatgagca aggaattaca cattaacaca attttggccc aggcgggtat
    94321 taagtcagat gaagcgacag gtgcattggt gacaccgctt catttttcaa cgacctatca
    94381 gcatccagag tttggtcgat ctactgggtt tgactatacg cgcactaaaa atccaactcg
    94441 tagtaaggct gaggaagtct tggcgactat tgagtcagca gactatgcct tagcgactag
    94501 ctcagggatg tcagctattg tactggcctt tagcggcttt ccagtaggaa gtaaggtctt
    94561 ggcagtgcgt gatctttacg gcggttcttt tcgctggttt aaccaagtgg agcaggaagg
    94621 tcgtttccat tttacctatg ccaatacaga agaagagttg attgccgagt tagaaaagga
    94681 tgtggatgtt ctctatatcg aaaccccaac caatcccttg atgttggaat ttgatatcga
    94741 aaaactagca aaattggctc atgctaaggg tgccaaagtg gtggtggaca ataccttcta
    94801 tagccctatc taccaacgtc cgattgaaga tggagcagat atcgttctcc attcagcaac
    94861 caagtatcta gcaggccaca atgatgtctt ggctggagtg gttgtgacca atagtttaga
    94921 actatacgag aagctttttt acaatctcaa tacaacaggg gcagtcttgt ctccatttga
    94981 cagctaccag ttgcttcgtg gtctcaagac cttgtctctt cgtatggagc gctcaacagc
    95041 taacgcccaa gaagtggttg cctttttgaa ggattctcca gcagttaagg aagttctcta
    95101 cactggtcgt ggaggcatga tttcctttaa agtagccgat gaaacacgca ttcctcatat
    95161 tttgaacagt ctcaaggtct tctcttttgc ggaaagtttg ggcggagtgg aaagtcttat
    95221 tacttatcca acgactcaaa ctcatgctga tattccagca gaagtacgcc attcttatgg
    95281 tttgacagat gacctcttgc gtttgtctat tgggattgag gatgctagag atttgattgc
    95341 agatttgcgc caagccttag aaggataaga caaagatggg aaaatatgat tttacaagcc
    95401 tgcccaaccg tttagggcac catacctata aatggaaaga aacagaaacg gatagtgaag
    95461 ttctaccagc ttggatagcg gatatggact ttgtggtctt gcctgaaatc cgccaagccg
    95521 tgcaaattta cgcagaccaa ctggtttatg gttataccta tgccagtgaa gacttaatta
    95581 aggaagttca aaagtgggaa gctacacaat acggttacaa ctttgacaaa gaggctcttg
    95641 tctttatcga gggtgtggta ccagccatct caacagctat tcaaaccttt acaaaagaag
    95701 gcgaggcggt tttaattaac acgcctgtct acccaccctt tgctcgcagt gtcaagttga
    95761 ataatcgtag attgattact aattccttag tggaaaagga tggtctgttt gagattgact
    95821 ttgaccaact tgaaaaggat ttggtggaag aggaggttaa actctatatt ctttgcaacc
    95881 ctcacaatcc tggtggacgt gtttgggaaa aagaagtgtt ggagaagatt ggccaactct
    95941 gccaaaaaca cggtgttttg ttagtttcgg atgagattca ccaagatttg accctctttg
    96001 gtcacaaaca ccagtctttc aataccatca atcctgcctt caaaaatttt gctatcgtct
    96061 tgagcagtgc cactaaaaca tttaatattg ctggaacaaa aaattcctat gcagtcattg
    96121 aaaatcctaa gttgagacta gctttccaga aacgcctgtt ggccaataat cagcatgaaa
    96181 tttcaggctt gggttatttg gcgacagaag ctgcctatcg atacggtaaa gattggctag
    96241 aggaactcaa gcaagtcttt gaagaccaca tcaattatgt ggtggatcta tttggaaaag
    96301 agactaaaat caaggtcatg aaaccgcaag gtacctactt gatttggctt gacttttcag
    96361 cttatgacct gactgatgaa acattgcaag agttgttgag aaatgaagct aaggttatcc
    96421 tcaaccgtgg tttggatttt ggagaggaag gaagtctcca tgcccgcatc aatatagcta
    96481 tgcccaaatc tctgttgcaa gaagtctgtc agcggattgt ggctactttt gccaaacgtt
    96541 aaaaatccag ccttctagga gaaaagtctt cctagaaggc tattttcata ggcgaaaata
    96601 tggtataata aaaagataag gtaaaggtga aaatatggct aaattgattc cggggaaaat
    96661 tcgtatcgaa ggtgttgccc tttatgaaac tggtaaggtt gatatcatca aggaaaagaa
    96721 caatcggctc tacgctcgcg ttgcagaaga agaactgcgc tatagtttag aggatgattt
    96781 ggttttttgt gcctgtgatt tttttcaaaa gaggggttac tgtgtgcatt tggcagcgct
    96841 agagcatttt ctgaaaaatg atgagcgtgg tcaggaaatc ttgtggagtc tggaagaagg
    96901 tcatgaagaa aaagaggctg ttgaaaccaa ggtaaccttg ggtggcaagt ttttggatcg
    96961 aattttatct ccaaaatcag aatgcgccta tgagttatca gctgtgggtc aggtggaagc
    97021 aggaaccaat catatcttgt ggactctgag aatcggccaa atcaatagcc aaaaatacta
    97081 tgtcattcgg gatattccac tttttttaag gattgtcgag cagagaaagt cgtatatgat
    97141 tggcaagatt tatgaggagt ctctttcttg ggaagccttt gatgatgcca gccaagaact
    97201 tttgactttc ttgcacggac taacggagga agggctggtt tcagacctct ttttccaaaa
    97261 ccaaggtcgg cacctctttt tccctctgac cttttttgag cagggtgtga atttactgat
    97321 ggccttgccc cattttcaat ttgaccatca agtggatagc taccaaaccc tgctttttca
    97381 ggatatgcat gctgatgcca atctatttgc ctttacagta acagaatact cggactattt
    97441 tgaaatggaa atcagtgaga gtcctagggt caatgtcttt tatcagggag cagtactttt
    97501 ccataaaggt caggtttatt ttttaacaga ccagcagatg cgtcttctca aggaaattaa
    97561 agcgttacct gtgggtcaac aaggaaagaa atacctgcaa tttgatagca gtgatcgaga
    97621 caaattggcc tcctgtctga ctctttttat ccagatgggc accgtttcag ctccagaacg
    97681 tctacaaatc aaaacttttg cgccctcttt ttactttgac agggaagaag ataatcggat
    97741 tcgtttagaa attcagtttg attatggaaa tagacaggta tctagccgac aagagctaga
    97801 agaattacca ttttcaagtg acgcggactt agaagaaaga attttccaag tctgtttggc
    97861 tgcgggcttt gaagccgatt ttcaatcttg gcgtcaggcc ttaaaagcgg agtctgtcta
    97921 tcattttttt catgatatca ttccagtctt tgaaaaactc gggcatgttg acctatcaga
    97981 taaactagaa gagctttata gcctagcgag tcctcaggtg cagattgcct ccaagggagg
    98041 tctcttggaa atccagtttg attttcaaga tattgcccag gaggaaatcg accaagccat
    98101 gcaggtcttg gttgccaatc aggattttta tattgattcg tctaatcaag tttacttttt
    98161 cgatgaagaa accaagaaaa ttcgccaaaa tctacaggaa ctggggcaat ttgaattaaa
    98221 agatgggacc ttgcaggctc ggaaatcctt ggcctacagt ttagctcatc tctttgaagg
    98281 gcgagaccgt gtttcttttt cacaagaatt ccagaatctg gcccaggatt tgacacatcc
    98341 agaggacttt cctcgacagg caactcaggt tcaggctgac ttgcgagatt atcaggaaaa
    98401 gggaattggc tggttgcaga tgctccatca ttatggtttt ggtgggattt tggctgatga
    98461 tatgggactt gggaaaaccc ttcagaccat tgcttttttg actagtcaag tgacaaaaga
    98521 aagtcgggtt ttgattctcg ctccgtcagg tttgatttac aactgggcag atgagtttca
    98581 gaaatttgcc ccacagttgg atgtggctgt tgttcatggt ttgaaagcaa gtcgtgagga
    98641 gattcttgcc gagagccatc aaatctatgt gactagctat gccaccttcc gtcaggacag
    98701 tgagttttat caggggatgg cctttgactt ccttttctta gatgaggctc aggtcatgaa
    98761 aaatgcccag accaagattg cccagacctt gagacaattt gtggtgccgt cggtctttgc
    98821 cttgtcagga actccgattg aaaaccatct gggtgagttg tggtctattt tccaaatcgt
    98881 catgcccgga cttttgccaa gcaagaaaga atttatgaaa ttgccagcag agcgagtggc
    98941 tcagtttatc aagcctttcg tgatgcgacg caagaaagaa gaagttctga ctgaattgcc
    99001 agacttgatt gaggtggttt ataaaaatga actggaagac cagcaaaagg ctatttacct
    99061 tgcccagtta caacagatgc gagaccatct ggctcaagtg tcagaacagg aatttcagcg
    99121 aagtcgtgtg gaaattttat ctggtttgat gcgcttgcgt caaatatgtg acactcctgc
    99181 cctgtttatg gaagattatc agggagccag cggcaaacta gatagtctcc gagacctact
    99241 ggtacaggtg gcagacggcg gacaccgtgt cttgattttc tctcagttca agggaatgtt
    99301 ggaaaaaatt gaacaagaac tgccagactt gggcctgaca tcctttaaaa ttacgggttc
    99361 aaccccagcc aaggaaagac aagacatgac caaggccttt aaccaaggag aaagagatgc
    99421 ctttctgatt tccctcaagg ctggtggggt cggtctgaac ctgacaggtg cagatacagt
    99481 gatcttggtt gacctttggt ggaatcctgc ggtggaagcg caagccattg gccgtgccca
    99541 tcggatgggt caggaagaaa cggttgaggt ctatcgcttg gtgaccaagg gaaccattga
    99601 agaaaaaatt caggaactcc aagaacaaaa gaaacatctg gtgtcacaag tattggatgg
    99661 cacagagtca cgtggtagtc tgaccctagc agaaattaga gaaattttgg gaatttctga
    99721 agccagcact tgaaaaatca agacaatacg ctataatgaa gtgttgaaag gaaatagaaa
    99781 atgaaacaag aacgatttcc attggtgtca gatgacgagg tcatgttgac tgaaatgcca
    99841 gtcatgaatc tctatgatga gtctgatctg atcagtaata tcaagggtga gtatcgagat
    99901 aaaaattatt tagaatgggc tcctattact gaagaaaaac cagtaaaacc gattgaaaag
    99961 caagtcgaaa aacctaaaaa ggctccttta ggggttaaaa aagaaggaaa gagctatgcg
   100021 gaggtggcgc gtgaagaagc gcgtgcggac ttgaaaaaga aacgctctgc taactaccta
   100081 actcaggatt tcagccttgc gagacgtcat tctcagccca gtctagttag acagggcaat
   100141 caaccgacaa ctcctttcca aaaggaaaat cctggtgaat ttgtcaaata tagccaaaaa
   100201 ttgacccagt ctcattatat cttggcggaa gaagttcatt ctatccctac caagaatgaa
   100261 gaagtgtcag cacctgctcc aaagaaaaac aattatgatt ttctaaagaa gagccaaatc
   100321 tacaataaaa aaagtaaaca aacagaacaa gaacgtcggg ttgcccaaga gttgaatctg
   100381 accagaatga cagaataggg gagaaaacat gtcaaagaca tatcatttta tcggaattaa
   100441 gggatcaggg atgagtgcct tggccttgat gttgcaccag atggggcaca aggttcaggg
   100501 atcagatgtt gaaaagtact actttaccca acgcggtctt gagcaggcag gaattaccat
   100561 tcttcctttt gatgaaaaga atctagacgg tgatatggaa attatcgctg gaaatgcctt
   100621 tcgtccagat aacaacgtcg aaattgccta tgcggaccaa aatggtatca gctacaaacg
   100681 ttaccatgag tttctaggta gctttatgcg tgactttgtt agcatgggag tagcaggagc
   100741 acatggaaaa acttcaacga caggtatgtt gtctcatgtc ttgtctcaca ttacagatac
   100801 cagcttcttg attggagatg ggacaggtcg tggttcggct aatgccaaat attttgtctt
   100861 tgaatctgac gaatatgagc gtcacttcat gccttaccac ccagaatact ctattatcac
   100921 caacattgac tttgaccatc cagattattt cacaagtctc gaggatgttt tcaatgcctt
   100981 taacgactat gccaaacaaa ttaccaaggg tctttttgtc tatggtgaag atgctgaatt
   101041 gcgtaagatt acgtctgatg caccaattta ttattatggt tttgaagctg aaggcaatga
   101101 ctttgtagct agtgatcttc ttcgttcaac aactggttca accttcaccg ttcatttccg
   101161 tggacaaaac ttggggcaat tccacattcc aacctttggt cgtcacaata tcatgaatgc
   101221 gacagccgtt attggtcttc tttacacagc aggatttgat ttgaacttgg tgcgtgagca
   101281 cttgaaaaca tttgccggtg ttaaacgtcg tttcactgag aaaattgtca atgatacagt
   101341 gattattgat gactttgccc atcatccaac agaaattatt gcgaccttgg atgcggctcg
   101401 tcagaaatac ccaagcaagg aaattgtagc agtctttcaa ccgcatacct ttacaagaac
   101461 cattgccctg ttggacgact ttgcccatgc tttaaaccaa gcagatgctg tttatctagc
   101521 gcaaatttat ggctcggctc gtgaagtaga tcatggtgac gttaaggtag aagacctagc
   101581 aaataaaatc aacaaaaaac accaagtgat tactgttgaa aatgtttctc cactcctaga
   101641 ccatgacaat gctgtttacg tctttatggg agcaggagac atccaaacct atgaatactc
   101701 atttgagcgt ctcttatcta acttgacaag caatgttcaa taggatgttc ccatggaaat
   101761 tccaattaag atcattcagg caagcaagtc tgatttgcct gagatagggg cacttcagac
   101821 ctcgtctttt ccagctgaaa agcagcaact ttcccatatt ttagaagaaa gtatccgtaa
   101881 gtgtgcggat acctttcttc tagctaggga tgaaaatcaa cttttaggct atattttatc
   101941 aagtccccag tcagacaatc cgcaatgtct aaaagtacat tctttagtca tcgagtctga
   102001 ccatcagaga cagggcctgg gaacacttct tcttgcagcc ttgaaagagg tggcagttga
   102061 gctggattgc aaagggattc gtttggagag tcctgatgag ctgctttcct attttgaaat
   102121 gaacggtttt gttgatgaag aagaaacttt gctctatgca actagccagg gctatagtat
   102181 gatttggttt aatccctttt atctggagga acaatgaaaa tcagacaagc aagattagaa
   102241 gatttggatc ggattgttga acttgaattt gaaaattttt cggtcgaaga agccattcct
   102301 ccttctgtct ttgaagcaca tttgagagaa attcagacct cttttctggt tgctgaaaaa
   102361 gaaggaagaa tcatgggtta tatcgaagga ccagttggcc tgcaccgcca tctgcaagac
   102421 cagtctttta cagaagaaat aaaagactat agtcatgagc ctggtggtta tatctctgtg
   102481 acctgtctgt ctattgccaa ggaggcacag ggactcggac tgggtcagaa attgctgaca
   102541 gccttgaaag aagttgctct tgaagatgag agagatggca ttaatctaac ctgtcatgac
   102601 tatctcatcg cctactatga aaaacatgga tttgtcaacg aaggccagtc ccagtcaacc
   102661 tttgcagggg aaacatggta tgatatggtc tgggaaatga aaaaataagt taggaaaagt
   102721 atcatagatt gctttttttg gacttttaag atataatatt atggattatc aacaaggagg
   102781 aaaaactttt gagtgaaaag tcaagagaag aagagaaatt aagctttaaa gagcagattc
   102841 tgagagattt agaaaaagta aaaggctatg atgaagttct gaaagaagat gaggcagtag
   102901 ttcgcactcc tgcaaatgaa ccttcagctg aagaactcat ggctgattcc ttgtcaacgg
   102961 tagaggagat tatgagaaaa gctcctaccg tgcctactca cccaagtcaa ggtgtaccag
   103021 cttctccagc agatgagatt caaagagaaa ctcctggtgt tccaagtcat ccaagtcaag
   103081 atgtaccttc ttctccagcg gaagaaagtg gatcaagacc aggtccaggt cctgttagac
   103141 ctaagaaact tgaaagagaa tacaatgaaa ccccaacaag ggtagctgtt tcctatacga
   103201 cggcagagaa aaaagcagaa caagcaggtc cagaaacacc tacgcctgct acagaaacag
   103261 tggatatcat cagcgataca tcacgtcgta gccgtagaga aggagcaaaa cccgttaaac
   103321 ctaagaaaga gaagaagtca catgtgaaag cttttgtgat ttcattcctt gtattccttg
   103381 ccttgctctc agcaggtggt tactttggtt accagtacgt gctagattct ttgttaccta
   103441 tcgatgctaa ttctaagaaa tatgtgacgg ttggaattcc agaaggttca aacgttcaag
   103501 aaatcggtac gacgcttgaa aaagctggtt tggtaaagca tggtctgatt tttagttttt
   103561 atgccaagta taaaaattat accgacttga aagcaggtta ctacaatttg caaaagagta
   103621 tgagtacaga agacttactc aaagagttgc aaaaaggtgg aacagatgaa ccgcaagaac
   103681 ctgtacttgc gactttgaca attccagaag gttatacctt ggatcagatt gctcaaactg
   103741 tgggtcaatt gcaaggtgac ttcaaagagt ctttgacagc ggaggctttc ttggctaaag
   103801 ttcaagatga gacgtttatc agtcaagcag tagcgaaata tcctacttta ctggaaagtt
   103861 tgcctgtaaa agacagcggt gcgcgttatc gtttggaagg ataccttttc ccagctacat
   103921 actctatcaa ggaaagcaca actattgaga gcttgattga tgagatgtta gctgctatgg
   103981 ataagaacct atctccttac tatagtacta tcaaatctaa aaacttgact atcaatgagt
   104041 tgttgaccat tgcttccttg gtcgaaaaag aaggtgccaa gacagaagat cgtaagctca
   104101 ttgcaggtgt attctacaat cgtttaaatc gtgatatgcc acttcaaagt aatattgcaa
   104161 tcttgtatgc ccaaggaaaa ctggggcaaa atatcagtct agctgaggat gttgcgattg
   104221 ataccgacat tgattcacct tataatgttt ataaaaatgt aggtctcatg cctggtccag
   104281 tcgatagtcc aagtctggat gcgattgagt caagcatcaa tcaaactaag agcgataacc
   104341 tctactttgt agcagatgtc acagaaggca aggtctacta tgctaacaat caagaagacc
   104401 acgaccgcaa tgtcgctgaa catgtcaaca gcaaattaaa ctaaacaaac taaaattatg
   104461 tgatacttca cataattttc tttagaaaat attatcagaa gaaagttgag aaaaatggca
   104521 gaaaaaacat atcctatgac ccttgaggaa aaggagaaac ttgaaaaaga attagaagaa
   104581 ttgaaattgg ttcgtcgacc agaagtggta gaacgcatta agattgcccg ttcatacggt
   104641 gatctttcag aaaacagtga gtacgaagca gctaaggatg aacaagcctt tgtcgaagga
   104701 caaatctcta gcttagaaac aaaaatccgc tatgctgaaa tcgtcaatag cgacgcagtt
   104761 gcccaggacg aagtagcgat tggtaaaaca gtcaccatcc aagaaattgg tgaggacgaa
   104821 gaagaagttt atattatcgt aggttcagct ggtgcggatg cctttgcagg taaggtttca
   104881 aatgaaagcc caattgggca ggccttgatt ggcaagaaaa caggtgacac agcaaccatt
   104941 gaaacgcctg ttggtagcta tgatgtaaaa atcttgaagg ttgaaaaaac agcctaaaaa
   105001 cagaaaaagg agtggggagg cgatgtgctt cactcactcc tttttccatt ttgctattct
   105061 tcgaaaatct cttcaaacca cgtcagcgtc gccttgccgt atatatggtt actgactttg
   105121 tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt ttcatctaca
   105181 acctcaaaac ggtgttttga gcagcctgcg cctagtttcc tagtttgctc tttgattttt
   105241 attgagtatt agatgtatag tgcattgaag ttaaaatagt acactttgat ttctaagaca
   105301 ttgttagaaa ttagattaaa ttccttaatc gatttgcgca tgttttattt catttcatta
   105361 tactttagat tggaaaataa ggaatcacat aaatcgcaag aaatagggaa tctgattcgt
   105421 gtttataacc gttcaaaaag agaagaggct gaaagtgagc cacttaatct ttatgtcgaa
   105481 gatgaaaagg gcaatctcct tgcgggtttg atagcagaga cttttggaaa ttggctagaa
   105541 atcgagtatt tgtttgtaaa agaggaactg cgagggcaag gaatcggttc aaaactattg
   105601 caacaggcag aaagtgaagc taagaatcga aattgttgtt ttgcctttgt caatacttac
   105661 cagttccagg caccggactt ttatcagaaa catggctaca aggaagtttt ttctttgcaa
   105721 gactatctct acattaggca aagatattat tatcaaaaga atctgtaagg tgagtatgga
   105781 ggtggactga tatatatgag taactatcga taaataccag ttataaccta gaaattgtgt
   105841 ctttctagac gatattgagg acaatataat cgtagcccca aaattaggaa tcaaggctta
   105901 tcaggttaag aaaagaagtg atgttgttga tattttaaaa caatttattt aaactaaaaa
   105961 ctctctatct ttttaaattg acattaatcc gagattcccc tctcggattt tgtgttgctt
   106021 tcattaaatt tacaggtaag acttgctagc ttcagtaaat atacacaagt ttttcagaat
   106081 agagtgaaat ccaaaagaaa atggaaataa tgaaagctct tgtaggcata agaaaacacc
   106141 tttgtgttat acttgttgtt caaccacaaa cacaagaaag gcacagagat gcaaaaccat
   106201 tatactacaa aaggcgaaca aagggaaatc aaatagagaa attgcctctc tacttggaaa
   106261 agctcctcaa actatccaca ctgaaatcaa gcgtaggaca gtccgacaat gtcttggaaa
   106321 agggcgcttc aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg
   106381 caagcgctcg gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta
   106441 tcataaccaa aaattttcgc ctgaaatgat ggttatggct aaaggggtta acgtgggaat
   106501 ttcaaccatt tactattgga ttcatcatgg aaaattgggg ttaagcaagc aggatttgcc
   106561 ttaccctaga aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg
   106621 tcaatccatc gaacagcggc ttgaagctat caattttcgc ttggagaatg ggcattatga
   106681 gattgataca gttctactta cgagagcgaa aaactactgc ttgcttgtct tgacggatcg
   106741 aaaaagtaga catcagatca tccgattgat tccaaataaa agtgctgagg tggtcaatca
   106801 ggctctaaaa ctcatcttaa aacaacacaa gattctttcc atcacggcag ataatggaac
   106861 ggaattcaat cgcttgtcta atgtattttc tgaggagcac atttattatg cacatcccta
   106921 tgcctcttgg gaaaggggaa ctaatgagaa tcacaacagg ctcattcgta gatggttacc
   106981 taagggaacc aagaaaatga ctcccaaaga agtcgcattc atcgaaaagt ggattaacaa
   107041 ctatcctaaa aaatgcttgg actacaagtc acccagagaa gacttttgga tggctaactt
   107101 gaacttgaaa tttagcaaaa tggaaataat ttttattaaa cgcttccaat agcggttaaa
   107161 agttgacaaa tttaaatttt aggactacac taagtaagta aattttattt taaaggagaa
   107221 tttgttatga atttaacatt tttaggctta tgtattgcct gtatgggcgt atctgtcggt
   107281 gaaggtttat tgatgaatgg actgtttaaa tcagtagcac gccaaccaga tatgctttct
   107341 gagtttcgta gtttgatgtt tttaggtgtt gcctttattg aaggaacttt ctttgtaact
   107401 cttgtcttct catttattat caaataaata catggaacga gaagaaaagg gaggatttta
   107461 gatggaagaa agtattaatc caatcatctc tattggtcct gttatcttca atctgactat
   107521 gttagccatg actttgttga ttgtgggagt tatttttgtc tttatttatt gggcaagccg
   107581 caatatgacc ttgaaaccca aaggaaagca aaatgtactt gagtatgtct atgactttgt
   107641 tattggattt acagaaccta acattggttc gcgctacatg aaagattatt cactcttttt
   107701 cctttgttta ttccttttca tggtgattgc caataacctt ggcttaatga caaagcttca
   107761 aacgatcgat gggactaact ggtggagttc gccaaccgct aatttacagt atgacttaac
   107821 cttatctttt cttgtcattt tgttgacaca tatagaaagc gttcgtcgtc gtggatttaa
   107881 aaaaagtata aaatctttta tgagtcctgt ttttgtcata ccgatgaata tcttggaaga
   107941 atttacaaac ttcttatctt tggctttgcg gatttttggg aatatctttg caggagaggt
   108001 catgacgagt ttgttacttc ttctttccca ccaagctatt tattggtatc cagtagcctt
   108061 tggagctaat ttggcttgga ctgcattttc tgtctttatt tcctgcatcc aagcttatgt
   108121 ttttactctt ttgacatctg tgtatttagg gaataagatt aatattgaag aggaatagaa
   108181 aggagtaact gatgcacgta acagtaggtg aattaattgg taattttatt ttaatcactg
   108241 gctcttttat tcttttgcta gtcttgatta aaaaatttgc atggtctaat attacaggca
   108301 ttttcgaaga aagagctgaa aaaattgctt cagatattga cagagctgaa gaagcccgtc
   108361 aaaaagcaga agtattggct caaaaacgcg aagatgaatt ggctggtagc cgtaaagaag
   108421 ctaagacaat cattgaaaat gcaaaggaaa cagctgagca aagtaaggct aatatcttag
   108481 cagatgctaa actagaagca ggacacttaa aagaaaaagc caatcaagaa attgctcaaa
   108541 ataaagtaga agctttacag agtgttaagg gtgaggtcgc agatctgacc atcagcttag
   108601 ctggtaaaat catctcacaa aaccttgaca gtcatgccca taaagcactc attgatcagt
   108661 atatcgatca gctaggagaa gcttaatgga caagaaaaca gtaaaggtaa ttgaaaaata
   108721 cagcatgcct tttgtccaat tggtacttga aaaaggagaa gaagaccgta tcttttcaga
   108781 cttgactcaa atcaagcaag ttgttgaaaa aacaggtctg ccttcttttt taaaacaagt
   108841 ggcagtagac gagtcggata aggaaaaaac aattgctttt ttccaagatt ctgtgtcgcc
   108901 tttattacaa aactttatcc aggttctggc ctacaatcac agagcaaatc ttttttatga
   108961 tgtgcttgta gattgcttga accgacttga aaaagaaaca aatcgatttg aagtgacgat
   109021 tacgtctgct catcctctaa ctgatgaaca gaagactcgt ttgctccctt tgattgagaa
   109081 aaaaatgtct ctgaaagtaa ggagtgtaaa agaacaaatc gatgaaagtc tcattggtgg
   109141 ttttgtcatt tttgccaatc acaagacaat tgatgtgagt attaaacaac aacttaaagt
   109201 tgttaaagaa aatttgaaat agaaagtggt gttcttttgg caattaacgc acaagaaatc
   109261 agcgctttaa ttaagcaaca aattgaaaat ttcaaaccca attttgatgt gactgaaaca
   109321 ggtgttgtaa cctatatcgg ggacggtatc gcgcgtgctc acggccttga aaatgtcatg
   109381 agtggagagt tgttgaattt tgaaaacggc tcttatggta tggctcaaaa cttggagtca
   109441 acagacgttg gtattatcat cctaggtgac tttacagata tccgtgaagg cgatacaatc
   109501 cgccgtacag ggaaaatcat ggaagtccct gtaggtgaaa gtctgattgg tcgtgttgtg
   109561 gatccgcttg gtcgtccagt tgacggtctt ggagaaatcc acactgataa aactcgtcca
   109621 gtagaagcac cagctcctgg tgttatgcaa cgtaagtctg tttcagaacc attgcaaact
   109681 ggtttgaaag ctattgacgc ccttgtaccg attggtcgtg gtcaacgtga gttgattatc
   109741 ggtgaccgtc agacagggaa aacaaccatt gcgattgata caatcttgaa ccaaaaagat
   109801 caagatatga tctgtatcta cgtcgcgatt ggacaaaaag aatcaacagt tcgtacgcaa
   109861 gtagaaacac ttcgtcagta cggtgccttg gactacacaa tcgttgtgac agcctctgct
   109921 tcacaaccat ctccattgct cttcctagct ccttatactg gggtcgctat ggcggaagaa
   109981 tttatgtatc aaggtaagca tgttttgatt gtatacgatg atctatcaaa acaagcggta
   110041 gcttatcgtg aactgtcgct cttgcttcgt cgtcctccag gtcgtgaagc cttcccaggg
   110101 gatgttttct atctccacag ccgtttgctt gagcgctcag ctaaagtttc tgatgaactt
   110161 ggtggtggat caattacagc cctaccattt atcgagacac aagcaggaga tatctcagcc
   110221 tatatcgcaa ccaacgtgat ttctatcact gatggacaaa tcttccttgg cgatggcctc
   110281 ttcaatgcag gtattcgtcc agccatcgat gcgggttcat ctgtatctcg tgtaggtggt
   110341 tctgcacaaa tcaaagccat gaagaaggtt gctggtacac ttcgtatcga ccttgcttca
   110401 taccgtgagt tggaagcctt tactaagttt ggttctgact tggacgcagc aacacaggct
   110461 aagttgaacc gtggacgtcg taccgttgag gtcttgaaac aacctgttca caaaccatta
   110521 cctgttgaga aacaagtaac cattctttat gctttgacac atggtttctt ggatactgtt
   110581 ccagtagatg atattgttcg tttcgaggaa gagttccatg ccttctttga tgctcaacat
   110641 ccagagattt tggaaaccat tcgtgataca aaagacttgc cagaagaagc agtcttggat
   110701 gctgcgatta cagagtttct caatcaatct agcttccaat aagaatagag gtgtcagatg
   110761 gcagtatctc taaatgatat taaaacaaaa atcgcctcaa caaaaaatac gagtcaaatc
   110821 actaatgcca tgcaaatggt atcggctgct aagctaggtc gctctgaaga agctgctcgc
   110881 aacttccaag tttacgctca gaaagtgcgt aaacttttga cagatatcct tcatggtaat
   110941 ggagctggtg cttcaactaa tccgatgttg attagccgtt ctgtgaagaa gacaggctat
   111001 atcgttatca cttcagaccg cggtttggtt ggaggttata attcctctat tttgaaagct
   111061 gttatggagt tgaaagaaga ataccaccca gacggtaaag gttttgaaat gatctgtatc
   111121 ggtgggatgg gagctgattt ctttaaggct cgcggtattc aaccacttta tgaattacgt
   111181 ggcttggcag accaacctag ctttgatcaa gttcgtaaga ttatttcaaa aactgttgaa
   111241 atgtaccaaa atgaactctt tgatgagctt tatgtttgct acaaccacca tgtcaatacg
   111301 ctaaccagtc aaatgcgtgt ggaacaaatg cttccgattg ttgacttgga tccaaatgaa
   111361 gcggatgaag agtacagctt gacttttgaa ttggaaacca gccgagaaga aattctggag
   111421 cagttgttgc ctcagtttgc agaaagtatg atttacggtg ccattataga tgccaagaca
   111481 gctgagaatg ctgcgggtat gacagccatg caaacagcga cagataatgc taagaaagtc
   111541 atcaatgatt tgacaattca gtataaccgt gccagacagg cggcgattac acaagaaatt
   111601 acagaaatcg tagcaggtgc tagtgcctta gaataggctc tagtccagct cgtatgaaaa
   111661 tgaacttagg acctagttga gctaggaacc gacagtatct tatatagaat aggagaagga
   111721 gatgagttca ggtaaaattg ctcaggttat cggtcccgtt gtagacgttt tgtttgcagc
   111781 aggggaaaaa cttcctgaga ttaacaatgc acttgtcgtc tacaaaaatg acgaaagaaa
   111841 aacaaaaatc gtccttgaag tagccttgga gttaggagat ggtatggttc gtactatcgc
   111901 catggaatca acagatgggt tgactcgtgg aatggaagta ttggacacag gtcgtccaat
   111961 ctctgtacca gtaggtaaag aaactttggg acgtgtcttc aacgttttgg gagataccat
   112021 tgacttggaa gctcctttta cagaagacgc agagcgtcag ccaattcata aaaaagctcc
   112081 aacttttgat gagttgtcta cctcttctga aatccttgaa acagggatca aggttattga
   112141 ccttcttgcc ccttacctta aaggtggtaa agttggactt ttcggtggtg ccggagttgg
   112201 taaaactgtc ttaatccaag aattgattca caacattgcc caagagcacg gtggtatttc
   112261 agtatttgct ggtgttgggg aacgtactcg tgaggggaat gacctttact gggaaatgaa
   112321 agaatcaggc gttatcgaga aaacagccat ggtctttggt cagatgaatg agccaccagg
   112381 agcacgtatg cgtgttgccc ttactggttt gacaatcgct gaatacttcc gtgatgtgga
   112441 aggccaagac gtgcttctct ttatcgataa tatcttccgt ttcactcagg ctggttcaga
   112501 agtatctgcc cttttgggtc gtatgccatc agccgttggt taccaaccaa cacttgctac
   112561 ggaaatgggt caattgcaag aacgtatcac atcaaccaag aagggttctg taacctctat
   112621 ccaggctatc tatgtgccag cggatgacta tactgaccca gcgccagcaa cagccttcgc
   112681 tcacttggat tcaacaacaa acttggaacg taagttggta caattgggta tctacccagc
   112741 cgttgaccca cttgcttcaa gctcacgtgc cttggcacct gaaatcgttg gagaagagca
   112801 ctatgcagtt gctgctgaag taaaacgtgt ccttcaacgt taccatgaat tgcaagatat
   112861 cattgctatc cttggtatgg atgaactttc tgatgaagaa aagaccttgg ttgctcgcgc
   112921 ccgtcgtatc cagttcttct tgtcacaaaa cttcaatgtt gcggaacaat ttactggtca
   112981 gccaggttct tatgttccag ttgctgaaac tgtacgtggc tttaaggaaa tccttgatgg
   113041 taaatacgac cacttgccag aagatgcctt ccgtggtgta ggttctatcg aagatgtgat
   113101 tgcaaaagct gaaaaaatgg gattttaaga ggtgaactat ggctcagtta actgtccaga
   113161 tcgtgacacc agatggtctc gtctatgatc accatgccag ctatgtatcg gttcgaactc
   113221 tggatggtga gatggggatc ttgccacgac atgaaaatat gattgcggtt ttagcagttg
   113281 atgaagtaaa ggtaaaacgt atcgatgata aagatcacgt gaactggatt gcagtaaacg
   113341 gtggtgttat tgaaattgcc aatgatatga tcacaatcgt cgctgactct gcagaacgtg
   113401 ctcgtgatat cgatatcagt cgtgcagaac gtgccaaact tcgtgcagaa cgtgcaattg
   113461 aagaagcaca agacaaacat ttgattgacc aagaacgtcg tgctaagatt gctttgcaac
   113521 gtgctattaa ccgtattaat gtcggaaata gactataaga aaaaatgaac ttgaaaatac
   113581 caagttcatt ttttatggtg ttttaaggag caaaacggat gcagactgct tcgggaacat
   113641 ggaagtcgtt ggagagttct gctagacgac cattgtcaca attacgttta aagacagttg
   113701 cattgtcaga gtcttgatgg acaacaatga gaaatttttg gtcgggtgtc aaatcaaaat
   113761 cacgtggagt ctgaccatgc gttggaacga tttctaataa ctctaagcta ccgtccgcaa
   113821 ggatggtata tactgcgata gaatcatggc cacggttaga agcgtagagg tatttaccgt
   113881 ctttagagag atgaatagca gcggttccat taaagccttc gtaagcttcc ggtaaagttg
   113941 aaatgacctg catacgttca aattcgccaa cgccatcgta gattaaaact tcgatagtac
   114001 tattgagttc acaaatgaga taagcgattt tatagtggtt atggaaaatg atatggcgtg
   114061 agcctgctcc tggcttgctg tgataggtat agagcttaga taattttcct tcttgatcga
   114121 ggtcataggt gatgacttgg tcagttccca agtcgcaggt cactagatag tggtcaggtg
   114181 ttaaatctgt atagtgaaca tggggggaag cttgattttc atgtggacct tggccactgt
   114241 gttgatccat atcactaagt agaagactac catcttcctg gcgtttataa acaaggactt
   114301 gtcccttgtg atagttggct gcgtaaacca aatcacgctt ttcatcgaca gcaacataac
   114361 agtggggagc tccttcttca acaacatgat ttaacacagt cccgtcagtt tgataggctg
   114421 caattccccc cttatcgtct tggctaccaa cagtgtataa atgttggtgc tggtcaaagg
   114481 caaggtaggt tggacttggc tcagctgcaa aaagttctag atttgaaagc tgaccagttt
   114541 ctgtatcaaa gtctgccttg taaatccctt gagaagtacg acgtgtataa gttccaaaat
   114601 aaacagtttc tttcattact atacctctgt gtaaagataa gactattata tcacaaaaac
   114661 aagtaaatta aagatatcca attagatgta agcactttaa aaaagagtta ttttgtttca
   114721 aaaatggtat aatgagagaa caatagaaag gaagtattta tggagcaaaa agagaaacat
   114781 tttagcctat cttggttttt caagtggttt ttagataaca aggcaattac ggtattttta
   114841 gtaaccttat tattgggact gaatcttttt attttaagta agattagttt tctattttca
   114901 cctgttttag actttttagc agttgtgatg ttgccagtca ttttgtctgg tttgttatat
   114961 tatttgttga atcctattgt tgattggatg gagaagcata aggttaatcg tgttatagct
   115021 atcactattg tctttgttat catcgctctc tttatcattt ggggcttggc agtcgccatt
   115081 ccaaatctgc aacgtcaggt tttgaccttt gcaagaaacg ttcctgttta cttagaagat
   115141 atagatagga ttgttaatgg attggtagcc cagcacctgc cagatgattt cagacctcaa
   115201 ttagagcaag ttttgaccaa tttttctagc caggctacag ttttggcaag taaggtttca
   115261 tctcaggcag tcaactgggt gagtgccttt attagcggag cttctcaagt gattgttgcc
   115321 ttgattatcg ttcctttcat gctcttttat ctcttgcgtg atgggaaagg cttgcgtaac
   115381 tatttgaccc aattcattcc aagaaaattg aaggaacctg ttggacaagt tttatcagat
   115441 gtgaatcaac agttgtccaa ctatgttcga gggcaagtga cagtggctat tattgtagca
   115501 gtaatgttta tcatcttctt caagattatt ggtctacgct atgcggttac gctgggggtt
   115561 actgctggta ttttaaatct ggtcccttat cttggtagct ttctagccat gcttcctgct
   115621 ctagtattgg gtttgattgc tggtccagtc atgcttttga aagtagtgat tgtctttatc
   115681 gtagaacaaa ctattgaagg ccgttttgtc tctccattga ttttgggaag tcaattaaac
   115741 atccacccta ttaatgttct ctttgttttg ttaacttcag gatctatgtt tggtatctgg
   115801 ggagttttac ttggtattcc ggtttatgcc tctgctaagg ttgtcatttc agccattttc
   115861 gaatggtata aggtagtcag tggtctatat gaattagagg gtgaggaagt caagagtgaa
   115921 caatagtcaa cagatgttac aggctttgga ggagcaagat ttaactaagg ctgagcatta
   115981 tttcgccaaa gctttagaaa atgattcaag tgatcttctg tatgagttgg caacttatct
   116041 tgaagggatt ggtttctatc ctcaggccaa ggaaatttac ctgaaaattg tagaggattt
   116101 tccagaggtt catcttaatc tagctgcaat tgctagcgag gatggtcaaa tagaagaagc
   116161 ctttacctat cttgaggaaa tccaagctga cagtgactgg tatgtctcgt ctttggctct
   116221 gaaggcagac ctttaccagc tggaaggttt gacagatgtg gcacgtgaga aattattgga
   116281 ggccttgacc tactcagagg attctctctt gatattgggt ttggcagagt tggatagtga
   116341 gttggaaaat taccaagcgg ctattcaagc ctatgcccag ttagataatc gctcgattta
   116401 tgagcaaacg ggcatttcca cctatcaacg aattggcttt gcctatgctc agttagggaa
   116461 atttgaaacg gctactgagt ttttagaaaa agccctggag ttagaatacg atgacttaac
   116521 agcttttgag ttggccagtc tttattttga tcaagaagaa tatcaaaaag ccaccctcta
   116581 ctttaagcag cttgatacca tttctcctga ctttgaaggc tatgagtatg ggtacagtca
   116641 ggctttacat aaggaacatc aagttcaaga agccctgcgt atcgctaagc aaggattaga
   116701 gaaaaatccc tttgaaactc gcctcttgct agctgcttca caattttctt atgaattgca
   116761 tgatgctagt ggtgcagaaa attatctcct tactgcaaaa gaagacgctg aggatacaga
   116821 agaaatcttg cttcgtttag ccactattta tctggagcag gagcgttatg aggatattct
   116881 agacttgcag agtgaggagt cagaaaatct tttgaccaag tggatgattg ctcgttctta
   116941 tcaagaaatg gacgatttgg atactgctta tgagcattat caagagttga taggagattt
   117001 gaaggacaat ccagaatttc tggaacacta tatctatctc ttgcgtgaat tgggacattt
   117061 tgaagaagca aaagtccatg ctcacactta cttaaaactg gttccagatg atgtgcaaat
   117121 gcaagaactg tttgagagat tgtaagaatg tttaaacata tagaactgta gtttatctct
   117181 tttgatagct acggttttta tttgtatatg gtagaatctt tttacaaaaa tacttggtaa
   117241 tcttgtttat tcatgctata ataggaacaa ttacttttag gaggtgcagt atgtcttatt
   117301 tatttgagat attaccgagt ttactgaatg gtgcgagcac gactgtacag gtctttgcac
   117361 tggtcttgct attttcgatt cccttgggcg ttttgattgc ctttgccttg caagtccatt
   117421 ggaagcccct ccattatctg attaacattt acatctgggt tatgcgagga acccccttac
   117481 tcttgcaact gatttttatc tattatgtgc tcccaagtat tgggattcgt ttagaccgcc
   117541 ttcctgcagc tattattgcc tttgttctca actatgcagc ttactttgca gaaattttcc
   117601 gtgggggaat tgacactatt ccaagaggac agtatgaggc cgccaaggtc ttgaagttta
   117661 gcccttttga cagagtgcgc tatattatct tgccccaagt gaccaagatc gttcttccta
   117721 gtgtctttaa tgaagttatg agtttggtca aggatacttc tttggtctat gctctcggaa
   117781 tttcagacct tatcttggct agtcgaacag ctgctaaccg cgatgctagt ctagttccta
   117841 tgttcttggc aggagccatt tatttgattt tgattgggat tgtgacaatt atttccaaaa
   117901 aagttgagaa gaagtatagt tattatagat aggaggctgc catgttagaa ttacgaaata
   117961 tcaataaagt ctttggagac aaacaaatcc tgtctaattt cagtctaagt attcctgaaa
   118021 agcaaatcct ggctatcgtt ggaccttctg gtggaggtaa gacaactctt ttacgtatgc
   118081 ttgcaggtct tgaaaccatt gattcagggc aaatctttta taatggacaa cctttagagc
   118141 tggatgaatt gcagaagcgc aatctactgg gatttgtatt ccaagatttt caactgttcc
   118201 ctcatttatc agttctggac aatttgacct tatcgcctgt gaagaccatg ggaatgaagc
   118261 aggaagaggc tgagaagaag gcgagtggac tcttggaaca gttaggacta ggaggacacg
   118321 cagaggccta tcctttctca ctatctggtg ggcaaaagca gcgggtggct ttggcgcgtg
   118381 ctatgatgat tgacccagaa atcattggct acgatgaacc aacttctgcc ctggatccag
   118441 aattacgttt ggaagtggag aagctaatct tgcaaaatag ggaacttggg atgacccaga
   118501 ttgtggttac ccatgatttg cagtttgctg aaaatatcgc agatgtatta ttgaaagtag
   118561 aacctaaata ggaggaaaaa tggatgaaaa aatggatgct tgtattagtc agtctgatga
   118621 ctgctttgtt cttagtagct tgtgggaaaa attctagcga aactagtgga gataattggt
   118681 caaagtacca gtctaacaag tctattacta ttggatttga tagtactttt gttccaatgg
   118741 gatttgctca gaaagatggt tcttatgcag gatttgatat tgatttagct acagctgttt
   118801 ttgaaaaata cggaatcacg gtaaattggc aaccgattga ttgggatttg aaagaagctg
   118861 aattgacaaa aggaacgatt gatctgattt ggaatggcta ttccgctaca gacgaacgcc
   118921 gtgaaaaggt ggctttcagt aactcatata tgaagaatga gcaggtattg gttacgaaga
   118981 aatcatctgg tatcacgact gcaaaggata tgactggaaa gacattagga gctcaagctg
   119041 gttcatctgg ttatgcggac tttgaagcaa atccagaaat tttgaagaat attgtcgcta
   119101 ataaggaagc gaatcaatac caaaccttta atgaagcctt gattgatttg aaaaacgatc
   119161 gaattgatgg tctattgatt gaccgtgtct atgcaaacta ttatttagaa gcagaaggtg
   119221 ttttaaacga ttataatgtc tttacagttg gactagaaac agaagctttt gcggttggag
   119281 cccgtaagga agatacaacc ttggttaaga agataaatga agctttttct agtctttaca
   119341 aggacggcaa gttccaagaa atcagccaaa aatggtttgg agaagatgta gcaaccaaag
   119401 aagtaaaaga aggacagtaa gataaaatag tggctgagac tgcgttttga ttagcaaaac
   119461 gcagtttttt tgtaatctag gaaaacgata atagcgattg aatctggata atttaatatg
   119521 gaatagccca ctgtgatttc taaaacattg ttaaaaattg atttgacttc caaaattaaa
   119581 atgttctgta atgaaatgct gatgtaactg ttttaggaac aataaaacgc ataatatcaa
   119641 ggtttttgca ccttacatta tgcgtttttg tgattttaag acttgttagc tgatttttta
   119701 caatcctgcg aaatctttga tttcttgtgc tgacattgaa gagtcgcaac ggacgttgat
   119761 ttgtccatct gtaatatgaa caaaacctgg tacagttggg attccatagc gtgagcggaa
   119821 tgcttgcaaa tcattgagtt ggcttggttc ttcactattg atgaagtaaa tgtgagcttt
   119881 ggtttcagct acgacacctg acaatgtacc tgcaaattta cggcagtaag ggcaagtttt
   119941 gcgaccgata aagaaggttg cagtttcttt tttatcaaga gcttcttgcg cacgcacaac
   120001 tgtagtgact tcaaggtctt tgatgttatc taaaaattgt tccatgagat tacctcgctt
   120061 tcattgataa gtctagtatg ccataaagtt tctaaaattg cttagatttg atacgaaaaa
   120121 agatgaggtt ggttggtctc atcttttata ggtctttatt ttacaaatgc attgatttct
   120181 gcttcgatgt tagcaatctt agcttgtgat tcttcgttgg tttcccctac aactgcaatg
   120241 tagaacttga tttttggttc tgtacctgaa gggcgaacgg caatccatga accgtcaaca
   120301 agtgtgtatt tcaacacatc acttggagga gttgtcaagt ttgtaacagt accgtcagca
   120361 acagtagcag tttgtgcctt gaagtcttct acgacagtga tagctgttgc gttccattct
   120421 tttggagcat tgttgcggaa tttagccata atcgctttga tttgttcagc accatcgaca
   120481 cctgaaagag taacagagat tgttttttct gcgtagtagc catattcttt atagatttct
   120541 tcgataccgt cagcaagtgt caaaccacga gaacggtagt aggcagcaag ttcagcaacg
   120601 acaagaacgg cttggatggc atctttatca cgtacaaatg gtttaatcaa gtaaccgaag
   120661 ctttcttcaa atcccatcat gtaagtgtgg ttgtgttttt cttcgaattc ttggattttt
   120721 tcagcgataa atttgaaacc tgtcaagacg ttgaacatag ttgcgccgta gctttcagca
   120781 atcttcgtta ccaagtcagt tgaaacgata gatttgcaga gagcggcatt ttcaggaaga
   120841 gttccagcgt ttttgtgagc ttccaagatg tatttagcca tgatagcacc gatttggtta
   120901 cctgaaaggt tgaggtagct accatctttt tgaagaactt caacaccaac acggtcagcg
   120961 tctgggtcag ttgcgacaag aacatctgca ccaacttgac gaccaagttc ttcagcaagg
   121021 gcaaaggctg cttggctttc tgggtttgga gatgttacag ttgagaagtc tgggtcagca
   121081 gttgcttgcg cttcaacaac ttgaacagag tcaaatcctg cttgggcaag agcacgacga
   121141 gccaacattt caccagtacc atgaagtggt gtgtagacaa tcttcatgtc tttaccaaat
   121201 tcttcaatca aggctgggtt gatgtttacg tccttaacct ctttaaggta ttctacgtca
   121261 acagcttcgc cgataacttc aatcaagcca gaagcttttt cagtttccac atcagcaact
   121321 tcaactgcaa atgggttttc gattgcacgg atataagtag tcaaagcgtc cgcatcgtgt
   121381 ggaggcattt gtccaccgtc ttcaccgtaa accttgtaac cgttaaatgg agcagggttg
   121441 tggctggctg tgaccatgat acctgcgaaa cagttgagat gacgaactgc aaatgatagt
   121501 tctggagtcg gacgaaggct ttcaaatacg taagatttga tgccgtgttt agcaagaact
   121561 gccgcagatt caaaggcaaa ctcaggtgag aagtgacggc tatcgtaggc aattgctaca
   121621 ccgcgttctt tctcgtttcc accttttgac tcaatcaaac gagccaatcc ttcagtagct
   121681 tggcgaacaa cgtagatgtt gatacggttt gtaccagcac caaccaagcc acgcatacct
   121741 gcagtaccaa attcaagatt tgtatagaag gcatcttcct tagttttttc gtccatattt
   121801 tccaaatctt gacgaaggta gtcaggaagc tccacaaaat caacccattt ctggtaattt
   121861 tcttggtaag acattcaaat tctcctttat ttttaaaaca tttaatcagt ttgattatat
   121921 catttttttt agttttagta aaaccttatc tgcttcgaac atctcttcaa accaggtcag
   121981 attgaatttt ggggttatat gatgttgagg ctaggaaaaa ttcaatttca gtaaaaaaag
   122041 taagtcttct cataacaaaa cattgatata gttgcttagt ttaaaataag catggtctaa
   122101 taaagctatg gcatataata ctgattttaa acaaggagca ttagattcca tcaaaggagg
   122161 gcacagacat gtcgaggcgg ccaaagtttt ttggtgttgg cgtcagaact ctcttcacgt
   122221 gggaaaagaa agacgtgaac aaaggaactt agagcggaaa aagcgagtcg tcaaaaagcg
   122281 taagatccct ttagaagaat tgaaagcctt tgtagaggct catccagatg cttttttacg
   122341 ggaaattgcg gcacattttg attgtgctgt tccttcagta tgggcagctt taaagcagat
   122401 taaggtcact ttaaaaaaag atgacgatct ttaaggaaca agagtcagag aaagtcgctg
   122461 agtttcttga tattttggat aacctaaaag atttaccaat cgtatatatt gatgaaacag
   122521 gaatcgaccg ctacctctat cgtccttatg caggggctcc tagaggggag aaagtctatg
   122581 aaaagattag cggacgtcgt tttgagcgaa cttcaattgt tgcaggacaa gtagacggag
   122641 agtttatagc tcccatgatt tacaagaaaa gcatgacaag cgatttcttt gtggagtggt
   122701 tcaaaacgca actcctacct gctttgaaga cgcctcatgt tattgtcatg ggcaatgcta
   122761 gttttcatcc caagaacatt ttggatgaac tctgcatcca agataaacac tttttcttac
   122821 ctctaccacc ttattcaccg gatttgaatc ctattgagca agcttgggct atcttgaaaa
   122881 agaaagtgac ggatttatta agggaagttc caactatttt tgaatgtttg gaatgctttt
   122941 ttaaaactag atgactataa cggttctaaa ggaacctatc gagtagtcat taaaactaag
   123001 gatactgctg gttaagagaa gacggtatac gatcaaacca ttcaccgtgt agccgaaatc
   123061 gttcagaatg aagacttgta tcagaatgaa gacttgtata agaaaggttt gaatgttgaa
   123121 cttgcgcacc aacaaattaa gggatttttt gaagcagaat ttaaaaatcg tattaatgga
   123181 gttcttaata ctaaaataaa aaatagtaca ttaaatcgtg taaataaaaa aactatacac
   123241 cagagcaaca aaaactccat gatcaatttg aagcagaagc aacggaagat gctaaaaaac
   123301 aaggcgatat tgtgttgaat gttgaccagg atttcatgag catatctaag tctaataaaa
   123361 gtgattcaga ctggaagaaa actttcacag tgaggacaac caataggtta gcaaatgact
   123421 tgaataatgt cttgaaacag gctgataaag atactcctaa taccccaact tggctaaact
   123481 cagctgcttc taaagctaaa gatgatgaca gagcatataa actactgaag actcttatac
   123541 caggagaaaa ttacctatca tgttaaggat aatcagctag aagtagaaac agataaatac
   123601 acatatactg ccgctagaaa tggtagtaag gaagttggta ttcaagagtc agatatagca
   123661 gcaactctaa gtgccgatga atataattct aatcgccaaa cctttgagag agaatacaaa
   123721 tacaaaagca aatgccctta ataatggttg ggctagatct ggttctgaag agttcaaaaa
   123781 gttctcccac tttgtagggg tagacaaagg gattgtgcga acgaatgtac tgactggtaa
   123841 aaaactatct gataagatta ggaaagaagt ggactctgga gatagcaaac taggaaaagg
   123901 cggctatttc tctactgggg atgttctatt aggaaaagat gttgtttctt ataccgtaca
   123961 agtattttca gagaataatg aaagagtagg agtaaacact caaagtcacc gtgttcagta
   124021 taatctccca attctagctg acttttcagt catccaagat actgtggaac catcacgaac
   124081 cgttgttgaa aaaatcattc caaaactaaa tattcccgaa gaagagaaag ggaaaataac
   124141 cgaagaaatc aagaaaaaga aaaaaacctc agaattggca gaactaatct cagaaaatgt
   124201 gaaagttcgc tatgttgatg aacaagggcg tttgctatca ttgaaaaatg atactggaat
   124261 tggagaaaaa gaaagtgacg gaacctacat taccaataaa aaacaactga ttggtaccag
   124321 ctacaatgtc acagataaaa aactcagtag catgactact actgacggaa aatattatac
   124381 ttttaaagaa gcagatacaa attctgcaag tttaactggg aatattgtaa gcgaaggtag
   124441 aacagtgacc ttagtttata gagaaagcga agcgccaacc actgctacag taacagccaa
   124501 ttactataaa gaaggtagcc aagagaagtt ggcagagtct gttataaaag ctgatttagc
   124561 gataggttct gagtatacca cagaatcaaa aactattgaa gggaaaacaa caactgagga
   124621 caaagaagac cgagttatca caaggaaaac aacatacacc ttggtagcaa ctcctgcaaa
   124681 tgcgtaccag aagacggtgc aacagttgac tattactacc gtgagaatgt tgaggaaaca
   124741 gtggttccca aaacagcaac ctctactgag acgaagacta taacgcgtat cattcattac
   124801 gttgataaag ttacgaacca aaatgtaaaa gaagatgttg ttcaacctgt aaccttaagc
   124861 cgtacaaaaa ctgagaacaa ggtcacggga gttgtaacct acggtgaatg gacaacagga
   124921 aactgggacg aggttgtatc tggtaagatt gacaagtaca aagatccaga tattccaaca
   124981 gttgaatcac aagaagttac gtcagactct agtgataaag aaataacggt aaggtatgac
   125041 cgtttatcaa caccagataa accaactcca gacccaggta ctccaaaaac tgaaactcca
   125101 gtgaatccag acccagaagt tccgacttat gagacaggta agagagagga attgccaaac
   125161 acaggtacag aagctaatgc taccttggct agtgctggta tcatgacctt gttagctggt
   125221 ctaggattag gattcttcaa gaaaaaagaa gatgaaaaat aatagatttt agaatctagg
   125281 aacaaggaaa agatcacaga tgtgggcttt ttcctggttt tgagaatgag gtctttcgtg
   125341 aagaataaaa acgcttacaa gtacgttgaa ctgggaaact atgaatccta tttttttaaa
   125401 aatatttcca gaaatcagtt gctaaatagg gtaaaaattg ataaaataag gaatatctaa
   125461 aaaattttaa ggagaatcta gcaaatggat ttcacatggg cactgaagta tgccactgaa
   125521 tttttgggaa ctgccatttt gatcattctt gggaatggtg cagttgccaa cgttgaactt
   125581 aaaggtacga aaggtcacca aagtggctgg atcgtcatcg ctgttggtta tggtatgggg
   125641 gttatgatcc cagccttgat gtttggtaac gtatctggga atcacatcaa ccctgctttc
   125701 actctagggc ttgcagttag cggtcttttc ccttgggcac aagtggtacc ttacattatc
   125761 gcgcaagtct tgggagctat ctttggccaa gccttagttg tggcaacata ccgtccattc
   125821 tacttgaaaa ctgaaaaacc aaataacatc ttgggaactt tctcaactat ttcaagtatt
   125881 gaccatggta caaaagaaag tcgctatgca gcaactgtca atggtttgat taatgagttt
   125941 gttggttcat ttgttttgtt ctttgcagct cttggtttga ctaaaaactt ctttggtgct
   126001 gaagtgcttc aattcatgaa acaaaaggca atagaagcag gacaaacagt tgatttttct
   126061 gacttggcta ttaaagcaca ggtggctcca cacactgctt caggactttc tgtggctcac
   126121 ttggcacttg gattcctcgt tatggctttg gtaacatcac ttggaggacc tacaggacct
   126181 gccttgaacc cagcccgtga cttgggacca cgtctccttc atgctttcct tccaaaatca
   126241 gttcttggtg agcataaagg cgattcaaaa tggtggtatt cttgggtacc agtagtagca
   126301 cctatcgcag cagcaattgc ggcagtagct gtattcaaat tcctttatct ctaagaaata
   126361 gctcctttaa catttgagtg agcaccatct ataagtaaga gaggatcaga ctggttctct
   126421 ctttttgatt ttttagggaa atgaaagaaa ctctaaacaa actcctctcc agcagtggtt
   126481 tagaagtctc agtgggctat tccagcttca atgggctata gtaggttgca gttgaaataa
   126541 tagacccttg tttctaaaac attgttagaa attggtttga attctccaat caaattgtgc
   126601 agttttcatt ctactatata ttatcggaga tgggttccct atcttgtaag tctgctttat
   126661 agtgggttga agttggaata gtcctccctt ctttctcaaa cattgtgagg aattgattta
   126721 ccttcctcaa caaaatgttc agtttctatt tcattttgct ataaaataag cgattaggag
   126781 ggctattctt cgacctacat tgactctgct gagtcctatg attgttatcg ttttatctgc
   126841 aattttatac tcaatgaaaa tcaaagggca aactaagaag ctagccgcag gttgttcaaa
   126901 acacagtttt gaggttgtat agtagattga aactagaata gtacacctca acttctaaaa
   126961 cattgttaga aatcgatttg actgtcctga tcgatttgcc ctattcttgt ttcattttac
   127021 tatataaacc agagactgtt tacattttca gcaagtgagt ggatggataa tgctgaaaac
   127081 tccttgaagg ataagtctat ttagtacttt ctattagtta gttaaatttt tatcaagaat
   127141 aattcacaaa aacgttgtaa aacacttgca atttagctga aatttgataa aatagtaagg
   127201 aaagttagac tgtattgcct actgtctatc tataaaatat attttattgg aggcttttac
   127261 tcaaatggca aaagaaaaat acgatcgtag taaaccacac gttaacattg gtactatcgg
   127321 acacgttgac cacggtaaaa ctaccctaac tgcagctatc acaactgttt tggcacgtcg
   127381 cttgccttca tcagttaacc aacctaaaga ctatgcgtct atcgatgctg ctccagaaga
   127441 acgcgaacgc ggtatcacta tcaacactgc gcacgttgag tacgaaactg aaaaacgtca
   127501 ctacgctcac atcgacgctc caggacacgc ggactacgtt aaaaacatga tcactggtgc
   127561 tgctcaaatg gacggagcta tccttgtagt agcttcaact gacggaccaa tgccacaaac
   127621 tcgtgagcac atccttcttt cacgtcaggt tggtgttaaa caccttatcg tcttcatgaa
   127681 caaagttgac ttggttgacg acgaagaatt gcttgaattg gttgaaatgg aaatccgtga
   127741 cctattgtca gaatacgact tcccaggtga cgatcttcca gttatccaag gttcagcact
   127801 taaagctctt gaaggtgact ctaaatacga agacatcgtt atggaattga tgaacacagt
   127861 tgatgagtat atcccagaac cagaacgtga cactgacaaa ccattgcttc ttccagtcga
   127921 ggacgtattc tcaatcactg gacgtggtac agttgcttca ggacgtatcg accgtggtat
   127981 cgttaaagtc aacgacgaaa tcgaaatcgt tggtatcaaa gaagaaactc aaaaagcagt
   128041 tgttactggt gttgaaatgt tccgtaaaca acttgacgaa ggtcttgctg gagataacgt
   128101 aggtgtcctt cttcgtggtg ttcaacgtga tgaaatcgaa cgtggacaag ttatcgctaa
   128161 accaggttca atcaacccac acactaaatt caaaggtgaa gtctacatcc ttactaaaga
   128221 agaaggtgga cgtcacactc cattcttcaa caactaccgt ccacaattct acttccgtac
   128281 tactgacgtt acaggttcaa tcgaacttcc agcaggtact gaaatggtaa tgcctggtga
   128341 taacgtgaca atcgacgttg agttgattca cccaatcgcc gtagaacaag gtactacatt
   128401 ctctatccgt gagggtggac gtactgttgg ttcaggtatg gttacagaaa tcgaagctta
   128461 attcgattta gttcccagaa gaacaattat ttaagtcaga cactaaaaga atcttgcttg
   128521 gcaaggttct ttttttagat attgaactaa tactcaatga aaatcaaaga gcaaactata
   128581 atatattgaa actagaatag tacacattta cttctaaaac attgttagaa atcgatttga
   128641 ctgtcctgat cgatttgtct tgttcttatt tcattttact atagaaagtt agctacagac
   128701 tgctcaaaac actgttttta ggttgtagat agaactgacg aagtcagtaa catctatacg
   128761 acaaggcgaa gctgacgcgg tttgaagaga ttttcgaaga gtataatact agactaaaat
   128821 caaaaagcat tatacaatag taatatgaaa tcaattaaag aagaaatcca aaccatcaaa
   128881 acacttttaa aagactctcg tacagctaaa tatcataaac gtcttcaaat cgttctattt
   128941 cgtctgatat gggcaaatct tataaagaga ttatagaact tttagactgt aatcaaacaa
   129001 tgatttggcg aaatgtaaaa aaatatgagg agttcggact cgactctctc cttcaagaaa
   129061 cacgtggtgg tcgtaaccat gcatatatga cagttgagga agagaaagtc tttcttgccc
   129121 gccatttgaa ggctgcagag gcaggagaat ttgttacaat tgatgcctta tttcaggctt
   129181 ataaaaagga gttaggtcgt tcctacacac gtgatgcctt ctatcaactg ttgaagcgcc
   129241 atggttggcg aaatattatg ccacgtccag aacatcctaa gaaagcagac gctcaaacca
   129301 ttgtcgcgtc taaaaataaa atctcaattc aagaagacaa gaaagcgttt taaatatagt
   129361 agacgttttc gtaaggttcg cttgatgtac caagatgagg ctggtttcgg tagaatcagt
   129421 aaactgggat cttgttgggc tccaatagga gtaggtccac atatccatag tcactatata
   129481 cgagaatttc gctattgtta tggagctgtt gatgcccata caggcgaatc atttttctta
   129541 atagctggta gatgtaatac tgagtggatg aacgcctttt tagaagagct ttcacaagct
   129601 tatccagatg attatttttt actcgttatg gacaatgcta tatggcataa atcaagtatc
   129661 ttaaagattc cgactaatat tggttttgca tttattcctc catacacacc agagatgaac
   129721 cccattgaac aagtgtggaa agagattcgt aaacgtggat ttaagaataa agcctttcga
   129781 attttggaag atgtcatgaa tcaacttcaa gatgtcatac aaggattgga gaaggaggtg
   129841 ataaagtcca tcgttaatcg gagatggact agaatgcttt ttgaaagcag atgagtataa
   129901 aattgaattg cttataaaaa agctccatac actggatgtg tatagagcaa tggggcttta
   129961 tttgatatag agttcttggt tttttaggac aatttctcgg atacttgcaa actttttaag
   130021 ttttttgatt tcttctggat gagtgacgag agtgataaca taaccttcct tgcccatacg
   130081 accagtacgg ccagcacggt gtgtgtaggt ttcgctatct ctaggaatat caaagtttac
   130141 gacacattct aggctatcga tatcaattcc acgagccaaa aggtcagttg caagaagcag
   130201 ggttagttgg ttatctttaa acttttctaa gatgattttt ctaaatttaa cattaacatc
   130261 actagcgagg gaaacagcca atatatcacg atactgtagt ttttcctcgg cattcccaag
   130321 gtctgacagg ctattgaaga agactagacc acggaaatcc tctacatgag ccagttttcg
   130381 tagcatatcc actcgatgac gttggtctac ctgcatgtag aaatgctgga tattgtccaa
   130441 tttttgatca gagagatcaa tagtgcgtgt attcggcaca atcttttctt ggtcaaactt
   130501 ggtcgtggca ctcatgtaga ccagttggtg gtcacgaggt gcgtagtgag tgattttctc
   130561 tacaaagtga atctgagaat catctagtaa ttggtcaaat tcatccagga tgatggtttc
   130621 cacattcatc atcttgattt ttttaagttt aatgagttca aagatacggc caggagttcc
   130681 aatcagaatt tctggcccct ttttaagacg ttcaatttgt cgtttctgac ttgaacctga
   130741 aaggaagagt tgagcagtca atccgatagc ttctgcccac gttttacata catcaaaaat
   130801 ctgtccagca agttccgtgt ttggtgctag aatcaagagt tgttgggctt ttttcttttg
   130861 tagtctgaga agacttggta ggagatacgc tagggtctta ccagttccgg tttggctcac
   130921 tcctaggagg ttttctccag caagaaggag ctcaaatagt tgagtttgaa tgggggtgaa
   130981 ttcttggaaa ccgagttggt cactcagttc ttgccattca gtcggtagtt tggttttcat
   131041 ttttctgcct caaatctaac gccagcagtc tggcgcatgg tatatagtag ctcatgaaca
   131101 gagcctgcat catacagcca agtttggtag agattcagat ctggttgctg gatcatgtgt
   131161 gcaaatgcag cgacttcctc agtcatcgta tgaggagcct gttggatagg aagctggact
   131221 tgatttcctt ggtggtcggt aaaaatagct gagcgaatat gctcaatcgt gttgagagtc
   131281 aaggttccat ctgttgtata aatctcgcaa ggaagattgg aagtgatgtt ttttccagcc
   131341 ttgatgtgaa cttgatagtc tgggtagaag aggataccat ctccatttag gtcaatgcta
   131401 ttgtcaagct gttgagcatg gtaagtcgcg tcattggctt ttccaaaaag acgaacagca
   131461 gcatagaggg gataaatccc caaatccatg agggctccac cagcaaaacg gtctgaaaag
   131521 acatttggtg tttgtccagt caacaagtca ggcatcttgg aagagtattt ggcatagttg
   131581 aaatctgctc ctaacacttg cttatctgct aaaaagtttt tgatagtagt aaaggctttc
   131641 tcgtggtaat tacgagctgc ttcaaagata aaacagttat ttttttcagc tgtttgaatc
   131701 aaatcaaacc attcttgtgg ttgagtgaca gctggctttt cgagaataac atgtttacca
   131761 gcagacaagg cagcttttgc ctgagcaaaa tgtaaggagt ttggactggc gatatagact
   131821 aaatcaaaag aagatttgaa gaagacttct aattgatcga atagttggat attctgatag
   131881 cgagaagcaa aggttgctgc agtttctagt tttctagaat agattgcgac cagttggtat
   131941 tctccactgg tatgggctgc ttctatgaaa tgatggctga tagcgccagt tccgatgaca
   132001 cctaatttta gcataaatac tccttttccg attttaaatc cttctttcat tataacatag
   132061 atagacggga ctatccaaca gagaggagaa aatttcaaat aagctattag ctttcttctg
   132121 aagaaaagct tttttttccg aataaataga tagaagcata gaatctagca aacctagatt
   132181 taaaaatgtg ctataataga aggaggaaaa ggaggattct cagacatccg ggtatcagcc
   132241 caactaatga tttgtcaatt tatctgcgat atgctggact tgccagcaaa aaatgtgacg
   132301 attttggagg gaagtaacat tcacgtcttg ccttccatgc cctactcagt gcaggatttc
   132361 tatactagta tagacgtctt ggcggagtta gataatggaa tccaagttat catcgaaatt
   132421 cagattcatc atcagaattt tttcatcaat cgcctatggg cttatctgtg cagtcaggtt
   132481 aatcaaaacc tagaaaaaat tcgccaacgt taaggtgata cccaccagag ctacaaacaa
   132541 atcgcaccag tatacgctat cgcaattgtc gatagtaatt acttctcaga tgacctagct
   132601 tttcatagtt ttatagtaaa atgaaatgag aataggacaa atcgatcagg acagtaaaat
   132661 cgatttctaa caatgtttta gaagtatagg tctactattc tagcttcaat ctactagaaa
   132721 ttccatagat agaaaactac ataatctcta cagatacgga tgttggagtt gatgtaagat
   132781 gctttggctt gctagaggaa ttgtggattg ccaaattgta tcattgaaat tattgctcaa
   132841 atttgttatg atataaatat gaataaaagt agactaggac gtggcagaca cgggaaaacg
   132901 agacatgtat tattggcttt gattggtatt ttagcaattt ctatttgcct attaggcgga
   132961 tttattgctt ttaagatcta ccagcaaaaa agttttgagc aaaagattga atcgctcaaa
   133021 aaagagaaag atgatcaatt gagtgaggga aatcagaagg agcattttcg tcaggggcaa
   133081 gccgaagtga ttgcctatta tcctctccaa ggggagaaag tgatttcctc tgttagggag
   133141 ctgataaatc aagatgttaa ggacaagcta gaaagtaagg acaatcttgt tttctactat
   133201 acagagcaag aagagtcagg tttaaaggga gtcgttaatc gtaatgtgac caaacaaatc
   133261 tatgatttag ttgcttttaa gattgaagag actgaaaaga ccagtctagg aaaggttcac
   133321 ttaacagaag atgggcaacc ttttacactt gaccaactgt tttcagatgc tagtaaggct
   133381 aaggaacagc tgataaaaga gttgacctcc ttcatagagg ataaaaaaat agagcaagac
   133441 cagagtgagc agattgtaaa aaacttctct gaccaagact tgtctgcatg gaattttgat
   133501 tacaaggata gtcagattat cctttatcca agtcctgtgg ttgaaaattt agaagagata
   133561 gccttgccag tatctgcttt ctttgatgtt atccaatctt cgtacttact cgaaaaagat
   133621 gcggccttgt accaatctta ctttgataag aaatatcaaa aagttgtcgc tctaaccttt
   133681 gatgatggtc caaatccagc aacgaccccg caggtattag agaccctagc taaatatgat
   133741 attaaagcga ctttctttgt gcttgggaaa aatgtttctg ggaatgagga cttggtgaag
   133801 aggataaaat ctgaaggtca tgttgttgga aaccatagtt ggagccatcc gattctctcg
   133861 caactctctc ttgatgaagc taaaaagcag attactgata ctgaggatgt gctaactaaa
   133921 gtgctgggtt ctagttctaa actcatgcgt ccaccttatg gtgctattac agatgatatt
   133981 cgcaatagct tggatttgag ctttatcatg tgggatgtgg atagtctgga ctggaagagt
   134041 aaaaatgaag catctatttt gacagaaatt cagcatcaag tagctaacgg ctctatcgtt
   134101 ttgatgcatg atattcacag tccgacagtc aatgccttgc caagggtcat tgagtatttg
   134161 aaaaatcaag gttatacctt tgtgaccata ccagagatgc tcaatactcg cctaaaagct
   134221 catgagctgt actatagtcg tgatgaataa gcaagaaaaa ataggtctgt tagatatttg
   134281 acagacttat tttttacaga agatagtact acttaaaaaa tgttttatgc tataattgat
   134341 gaataaaata gaaggagaag catatgaata cctatcaatt aaataatgga gtagaaattc
   134401 cagtattggg atttggaact tttaaggcta aggatggaga agaagcctat cgtgcagtgt
   134461 tagaagcctt gaaggctggt tatcgtcata ttgatacggc ggcgatttat cagaatgaag
   134521 aaagtgttgg tcaagcaatc aaagatagcg gagttccacg tgaagaaatg ttcgtaacta
   134581 ccaagctttg gaatagtcag caaacctatg agcaaactcg tcaagctttg gaaaaatcta
   134641 tagaaaaact gggcttggat tatttggatt tgtatttgat tcattggccg aacccaaaac
   134701 cgctcagaga aaatgacgca tggaaaactc gcaatgcgga agtttggaga gcgatggaag
   134761 acctctatca agaagggaaa atccgtgcta tcggcgttag caattttctt ccccatcatt
   134821 tggatgcctt gcttgaaact gcaactatcg ttcctgcggt caatcaagtt cgcttggcgc
   134881 caggtgtgta tcaagatcaa gtcgtagctt actgtcgtga aaagggaatt ttattggaag
   134941 cttgggggcc ttttggacaa ggagaactgt ttgatagcaa gcaagtccaa gaaatagcag
   135001 caaatcacgg aaaatcggtt gctcagatag ccttggcctg gagcttggca gaaggatttt
   135061 taccacttcc aaaatctatc acaatctctc gtattcaggc taatcttgat tgctttggaa
   135121 ttgaactgag tcataaggag agagaaacct taaaaacgat tgctgttcaa ttgggtgctc
   135181 cacgagttga tgatgtggat ttctagaaaa tcataaaaag aattgtacat tattctaatt
   135241 tttgatataa tagtcagcag gaaagaaagt cttatggcgt tcttcaagcg agcttgggac
   135301 agtgggagcc aagtagggca aaataatggg ctggcgcttt ctgtagtatt ttcaaaaaca
   135361 atgaagtaat aaattagggt ggaaccgcgt ttctgacgcc cctaggttaa atcaacctag
   135421 gcttgtcaga tgtggttctt ttgcttattc agtctattgt gtgaaagaaa ggagagccgt
   135481 ggacaacctt tatcttgtaa aagacgatag tcaactagct acatttcgtg attttgtagt
   135541 aagaaatact gaaaagttga aagattatca atctttttta aagaatgaac ttgcagtctg
   135601 tgatttaccg caagccgtta tttggtcaga tcttaatgct gctacacaga ttattaggga
   135661 aagtgctgtt ccagcctata caaataatag acgaatggtt atgacgcctg atttagctgt
   135721 ttggaaagag ttgtatttgt atcagttgat ggactacgag tgttctgagc aaactcaagc
   135781 aatagaaagc cactatcatt ctttatctga aaatttcctc ttacagattg taggacatga
   135841 gttagctcat tggtcggagc attttttaga tgattttgat ggttatgact cttatatctg
   135901 gttcgaagag gggatggttg aatatattag tcgcaagtat ttcttgacag aagaggaatt
   135961 tcaagcggaa aaaatttgta atcaatctct cgtagaactt tttcagaaga agtatggttg
   136021 gcattcattg aatgattttg gttcttcgac ttatgataag aactatgcaa gtatttttta
   136081 tgaatactgg cgcagctttt tgacagtaga taagttggta gaaaatttag gtagtgtaca
   136141 agcggtcttt gattcttatc atttatgggc aaatacagaa aaaacttttc ccttgttaga
   136201 ttggtttgtt cagcagaaat taattgaaaa agaaatataa aaactaaagg agtattcaat
   136261 gtctgagaaa ttaacatttc actgcatcag tggcagaaac ctccttacag tcggactgcc
   136321 ccacgctcag cactagagtg cctgagctag acgcagtact aactcgtctt gcctcgtatg
   136381 atcgacgagg cagactcgtg tcgcaagtaa ttatttttta ttaaggagta ttcaatgtct
   136441 aagaaattaa catttcaaga aattattttg actttgcaac aattttggaa tgaccaaggt
   136501 tgtatgctta tgcaggctta tgataatgaa aaaggtgcgg gaacaatgag tccttacact
   136561 ttccttcgtg ctatcggacc tgagccatgg aatgcagctt atgtagagcc atcacgtcgt
   136621 cctgctgacg gtcgttatgg ggaaaaccct aaccgtctct accaacacca ccaattccag
   136681 gtggtcatga agccttctcc atcaaatatc caagaacttt accttgagtc tttggaaaaa
   136741 ttgggaatca atcctttgga gcacgatatt cgttttgttg aggacaactg ggaaaaccca
   136801 tcaactggtt cagctggtct tggttgggaa gtttggcttg acggaatgga aatcactcag
   136861 ttcacttatt tccaacaagt cggtggattg gcaactggcc ctgtgactgc ggaagttacc
   136921 tatggtttgg agcgcttggc ttcttacatt caagaagtag actctgtcta tgatatcgag
   136981 tgggctgatg gtgtaaaata cggagaaatc tttatccagc ctgagtatga gcactcaaaa
   137041 tattcatttg aaatttcgga ccaagaaatg ttgcttgaaa actttgataa gtttgaaaaa
   137101 gaagctggtc gtgcattaga agaaggcttg gtacaccctg cctatgacta tgttctcaaa
   137161 tgttcacata cctttaatct gcttgacgcg cgtggtgccg tatctgtaac agagcgtgca
   137221 ggctatatcg ctcgtatccg taacttggcc cgtgttgtag ccaaaacctt tgttgcagaa
   137281 cgcaaacgcc taggttaccc acttttggat gaagaaacac gagttaaact tttagcagaa
   137341 gacgcagaat aaagagagtg acaaattacg aaaatgggcg aacagagtga gccctgagcc
   137401 agttgccgca gtgatgaagg tatccttagt gaaactaagg atactaggca aaattggaga
   137461 cttttggctc caattttagc aatgaaacaa cgaagttggt tgcttgcgtg ccaatcacat
   137521 aaggcaaact ggaaaataaa aagatacttt tcggagaaaa aacatgacaa aaaacttatt
   137581 agtagaactc ggtcttgaag aattaccagc ctatgttgtc acaccaagtg aaaaacaact
   137641 aggcgaaaaa atggcagcct tcctcaagga aaaccgcctg tcttttgaag ccattcaaac
   137701 cttctcaaca ccacgtcgtt tggctgttcg tgtgactggt ttatcagaca aacagtctga
   137761 tttgacagaa gatttcaagg gaccagcaaa gaaaattgcc ttggatagtg atggaaactt
   137821 caccaaagca gctcaaggat ttgtccgtgg aaaaggcttg actgttgaag atatcgaatt
   137881 ccgtgaaatc aagggtgaag aatatgtcta tgtcactaag gaagaagttg gtcaagcagt
   137941 tgaagccatt gttcctggtg ttgtagatgt cttgaagtca ttgactttcc ctgtcagcat
   138001 gcactgggct ggaaatagct ttgaatacat ccgccctgtc cacactttaa ctgttctctt
   138061 ggatgagcaa gagtttgact tggatttcct tgatatcaag ggaagtcgtg tgagccgtgg
   138121 ccatcgtttc ttggggaaag aaaccaaaat tcagtcagca ttgagctatg aagaagacct
   138181 tcgtaagcag tttgtaatcg cagatccatg tgaacgtgag caaatgattg ttgaccaaat
   138241 caaggaaatt gaggcaaaac atggtgtacg tatcgaaatt gatgcggatt tgctgaatga
   138301 agtcttgaat ttggttgaat acccaactgc cttcatggga agttttgatg ctaaatacct
   138361 tgaagttcca gaagaagtct tggtgacttc tatgaaggaa caccagcgtt actttgttgt
   138421 tcgtgatcaa gatggaaaac tcttgccaaa cttcatttct gttcgtaacg gaaacgcaga
   138481 gcgtttgaaa aatgtcatca aaggaaatga aaaagtcttg gtagcccgct tggaagacgg
   138541 agaattcttc tggcgtgaag accaaaaatt ggtgatttca gatcttgttg aaaaattaaa
   138601 caatgtcacc ttccatgaga agattggttc ccttcgtgaa cacatgattc gtacgggtca
   138661 aatcactgta cttttggcag aaaaagctgg tttgtcagtg gatgaaacag ttgaccttgc
   138721 tcgtgcagca gccatttaca agtttgactt gttgacaggt atggttggtg aatttgacga
   138781 actccaagga attatgggtg aaaaatacac ccttcttgct ggtgaaactc cagcggtggc
   138841 agctgctatt cgtgaacact acatgcctac atcagctgaa ggagaacttc cagagagcaa
   138901 ggtcggcgca gttctagcca ttgcagacaa attggatacg attttgagtt tcttctcagt
   138961 aggattgatt ccatcaggtt ctaatgaccc ttatgccctt cgtcgtgcaa ctcaaggtgt
   139021 ggttcgtatc ttggatgcct ttggttggca cattgctatg gatgagctga ttgatagcct
   139081 ttatgcattg aaatttgaca gtttgactta tgaaaataaa gcagaggtta tggactttat
   139141 caaggctcgt gttgataaga tgatgggctc tactccaaaa gatatcaaag aagcagttct
   139201 tgcaggttca aactttgttg tggcagatat gttggaagca gcaagtgctc tcgtagaagt
   139261 aagcaaggaa gaagatttta aaccatctgt tgaatcactt tctcgtgcct ttaacctggc
   139321 tgagaaggca gaaggggttg ctacggttga ttcagcacta tttgagaatg accaagaaaa
   139381 agctttggca gaagcagtag aaacactcgt tttatcagga cctgcaagtc agcaattgaa
   139441 acaactcttt gcgcttagcc cagtcattga tgctttcttt gaaaatacta tggtaatggc
   139501 tgaagatcag gctgtccgtc aaaatcgttt ggcaatcttg tcacaactaa ccaagaaagc
   139561 agctaagttt gcttgtttta accaaattaa cactaaataa aatttgataa acggacttta
   139621 tcttattaca gaggagaaga aatggatccg aaaaaaattg ctcgtatcaa tgagcttgct
   139681 aaaaagaaaa aaacagaagg cttaacacca gaagaaaaag tggaacaagc caaactacgt
   139741 gaggagtaca tcgaaggtta tcgccgcgct gttcgtcacc acattgaagg aatcaaaatt
   139801 gtggacgaag aaggaaacga tgttacacca gaaaaactac gccaagtaca acgtgaaaaa
   139861 ggattacatg gccgtagtct tgatgaccca aattcataat aatactcttc gaaaatcaaa
   139921 ttcaaaccac gtcagcttca ccttgccgta cttaagtaca gcctgcggct agcttcctag
   139981 tttgctcttt gattttcatt gagtataagt attctttctt ttaacaagga tagatgaaac
   140041 gataacaaag agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat
   140101 aatggttcct aaaaactatc attagtaact tgcaccggct gtagcgtctg cgtcaccacc
   140161 gtggcctcca gcatcccctg aatcagaagc gccagaagta gcatcggcgt ctccatgacc
   140221 tccggcagca ggagcaaatg gtccgctacc acccaccaaa cgttgaccag tctcttttag
   140281 gtaccagtca agccatggtt ggaagttaaa gacgatttca ttgataccag cgtatgatcc
   140341 atcaggatag tacattgctt ggtagttgtg agtgttgata acacctgcag gagaacctgg
   140401 aacgatcgta cggacgtatt cttggtttcc gttgcgaagt gttccgataa cccactctac
   140461 gttcttcata cgtgctggtg gaagagaacc atgaacagtc gacatacggc tacctgattg
   140521 aggtggtaca cgtttagcga acatagtgtc tggatcttgg tgagcgttgt tgtagtagag
   140581 gaattggttg ttatcgtcag cgtatgtcaa ttcaaatggc atagctttca agaacatatc
   140641 aatttggtta actgttagga taccgtggtc caatttgaca taggtatcac cagaaacagc
   140701 accagtgatt gctgcaactt tttctaccca ttctggatcg tcagggtcaa cttctgtgat
   140761 ggttgtagcg attggttttc cacaatccaa gtcttctgat tcgattggtt ttggtttttt
   140821 caatttcgaa acgactccta cgtatttaac aaagttatct aagcaagttt caaggaattt
   140881 aacagtgcct tcgttggtga tatttccgtt gttatcaaaa gcttccttag ctttaccaag
   140941 aaggaattcg ttacctggaa gcgtgtaggc attaacacct ggagcatcaa ggattttacg
   141001 aaggtgaact tgagcacgtg atgttccttg gtcatagtat gatgcaccca caatcataac
   141061 aggcttgttt tcaaatggat gaacttcgta tgaaagccat tcaagtacag atttgagtga
   141121 agctgagata gtgtggttat gctcaggagt agcaatgata acaccatctg cacgagtaat
   141181 tttgttatat aaataacgta attggaaact ttcatcccat ttttcatctt ggttaaacat
   141241 tggaacttcg tcaatttcaa gaacttctaa ttcaaatttg agtttgaagt agcgacggat
   141301 aaattccaag agcttacggt tatatgattg atcgtagttt gatccaacaa gtccaacaaa
   141361 tttcattctt tttggtctcc tatcttacaa attttcccag tcaaagtctt cagcatcttt
   141421 gcgaagtaat tcttgtgcat tacgtaattt ttctgtgatt tttacaaaga tacggaagtc
   141481 atcaaagatg gcatccaatt tcttgataac atcaaggtca accaagtcgc cacttgggtt
   141541 aaatgcttga agagagtgtg agagcaagaa ttcatctgga agaacatttg ccttgatttc
   141601 aggagcattc aagatttgac gaagttgcaa ttgggcacga gatgaaccaa gcgtaccgta
   141661 agaagcacct gtaatcatga ttggtttgtt caaaagtggg taaataccat aagacaacca
   141721 agcaagagcg ctcatcaaaa cagctggaat agagtgatca tactcaggag taccgataat
   141781 aacgccatct gtctcttcga ttttagcagc aatttccaat atttcagcag gtacttgctt
   141841 gtcagctggt ttgttgaaga caggaatggc cttgatttca acaagctcaa tttcagcttt
   141901 gtcagcaaag tgtttttgca tgtattgaag caattgacgg tttgtagaac gttttgaatt
   141961 tgttccaaca atagcaataa gttttaacat gagatttcct ttctcttttt acataataca
   142021 attttaaaat tccattgaaa cagttgtctc tatagagtag gaattcctga agaacagctt
   142081 aggtggcctt ctttatcgat gaggatgact tcgatgcctt ccaaactttc gacttgccag
   142141 aggatagaag caggtctttc tccaaagagt cgagtcgtcc agatttcgcc atcgactgat
   142201 ttatcagaga tgattgttag actcgctagt tccgtttcaa caggatatcc tgtttgactg
   142261 tcaaaaatgt gatggtaatc ttgtccatcg acggtcaggt gacgttcata aatgcctgaa
   142321 gtcacgacag atttattgac aacagggatg gtcattaaat gatttcccct aggattggct
   142381 gggtcttgaa tcccgatttg ccatgggtta tcccctcttg cctgattttt tccaatggtc
   142441 aggatattcc ctcccagatt gatcaaggca gaagtcaccc cctctttcct aagaaattgg
   142501 gcaaccttat ccgcactgta tcctttggct aaacaaccta gatcgatctt cattcctttc
   142561 tgttttaaaa acacagtaga agtagaagaa tctaactcga taccatgagg attgattaga
   142621 ggcagcaccg attcaatttc ttgaggctgg gcgaccttgg catctgaaaa accgatacgc
   142681 caggtttgaa ttaagggacc aatgctgata ttgaggtggc tagagagcgc taggctatgc
   142741 tctaacccaa gtgaaatcag ctcaaacagg tctggatgaa ccgtgacggg ggctattcct
   142801 gcttgataat tgatttccat caactcagat tcttgactat tggcgttgaa gcggtattca
   142861 agttctttga gcaagtcaaa ggatttttgg agaaagatat cggcttgctc atccactaat
   142921 gaaatagtga tagtagtccc cattagccgt tcagaatgtg aacgaagagt caagctacca
   142981 actcctttct cttatagaaa ataagttgta atatcaaata atcatctaaa ttgaagccct
   143041 tacatt
//
LOCUS       DAVMCN010000002       102795 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVMCN010000002 DAVMCN010000000
VERSION     DAVMCN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 102795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 102795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.002"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            183..365
                     /locus_tag="VYP85_000166"
     CDS             183..365
                     /locus_tag="VYP85_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1880738.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            310..1159
                     /locus_tag="VYP85_000167"
     CDS             join(310..723,725..1159)
                     /locus_tag="VYP85_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1880739.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDARFKRLVGVQRTTFEEML
                     AVLKTTYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRSQ
                     WVEATLVQSGVTISRTPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIV
                     TSQGRIVSLDITVNYCHDMKLFKMSRRNIGQAGKILADSGYQGPMKIYPQAQTPRKSS
                     KLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLIAGII
                     NHELGF"
     gene            complement(1231..1593)
                     /locus_tag="VYP85_000168"
     CDS             complement(1231..1593)
                     /locus_tag="VYP85_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880740.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHTFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(1971..3851)
                     /locus_tag="VYP85_000169"
     CDS             complement(1971..3851)
                     /locus_tag="VYP85_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1880741.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3845..4714)
                     /locus_tag="VYP85_000170"
     CDS             complement(3845..4714)
                     /locus_tag="VYP85_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1880742.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4798..7443)
                     /locus_tag="VYP85_000171"
     CDS             complement(4798..7443)
                     /locus_tag="VYP85_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1880743.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(7534..8814)
                     /locus_tag="VYP85_000172"
     CDS             complement(7534..8814)
                     /locus_tag="VYP85_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1880744.1"
                     /translation="MVYSKEIVREWLDEVAERAKDYPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8986..11070
                     /locus_tag="VYP85_000173"
     CDS             8986..11070
                     /locus_tag="VYP85_000173"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1880745.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALQQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELDYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGISLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(11110..12789)
                     /locus_tag="VYP85_000174"
     CDS             complement(11110..12789)
                     /locus_tag="VYP85_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1880746.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            13545..14774
                     /gene="arcA"
                     /locus_tag="VYP85_000175"
     CDS             13545..14774
                     /gene="arcA"
                     /locus_tag="VYP85_000175"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1880747.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14832..15848
                     /gene="argF"
                     /locus_tag="VYP85_000176"
     CDS             14832..15848
                     /gene="argF"
                     /locus_tag="VYP85_000176"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1880748.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            16013..16960
                     /gene="arcC"
                     /locus_tag="VYP85_000177"
     CDS             16013..16960
                     /gene="arcC"
                     /locus_tag="VYP85_000177"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1880749.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            17169..18680
                     /locus_tag="VYP85_000178"
     CDS             17169..18680
                     /locus_tag="VYP85_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1880750.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18702..20033
                     /locus_tag="VYP85_000179"
     CDS             18702..20033
                     /locus_tag="VYP85_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1880751.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(20440..20730)
                     /locus_tag="VYP85_000180"
     CDS             complement(20440..20730)
                     /locus_tag="VYP85_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880752.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDKVAQI"
     gene            complement(20718..20969)
                     /locus_tag="VYP85_000181"
     CDS             complement(20718..20969)
                     /locus_tag="VYP85_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1880753.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            21173..21250
                     /locus_tag="VYP85_000182"
                     /pseudo
     CDS             21173..21250
                     /locus_tag="VYP85_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21368..22252)
                     /locus_tag="VYP85_000183"
     CDS             complement(21368..22252)
                     /locus_tag="VYP85_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1880754.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(22397..23548)
                     /locus_tag="VYP85_000184"
     CDS             complement(22397..23548)
                     /locus_tag="VYP85_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1880755.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(23694..25460)
                     /locus_tag="VYP85_000185"
     CDS             complement(23694..25460)
                     /locus_tag="VYP85_000185"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1880756.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(25473..26201)
                     /locus_tag="VYP85_000186"
     CDS             complement(25473..26201)
                     /locus_tag="VYP85_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEV1880757.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            complement(26216..29233)
                     /locus_tag="VYP85_000187"
     CDS             complement(26216..29233)
                     /locus_tag="VYP85_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEV1880758.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLTKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            complement(29244..31460)
                     /locus_tag="VYP85_000188"
     CDS             complement(29244..31460)
                     /locus_tag="VYP85_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1880759.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCVETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSRFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            complement(31482..33352)
                     /locus_tag="VYP85_000189"
                     /pseudo
     CDS             complement(31482..33352)
                     /locus_tag="VYP85_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
     gene            complement(33358..34677)
                     /locus_tag="VYP85_000190"
     CDS             complement(33358..34677)
                     /locus_tag="VYP85_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1880760.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDRYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            complement(34674..35513)
                     /locus_tag="VYP85_000191"
     CDS             complement(34674..35513)
                     /locus_tag="VYP85_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1880761.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPIDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            complement(35516..36445)
                     /locus_tag="VYP85_000192"
     CDS             complement(35516..36445)
                     /locus_tag="VYP85_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1880762.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            36511..37119
                     /locus_tag="VYP85_000193"
     CDS             36511..37119
                     /locus_tag="VYP85_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880763.1"
                     /translation="MTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLD
                     SSTTVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNY
                     DKENSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFY
                     KTGFFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(38248..39753)
                     /gene="adcA"
                     /locus_tag="VYP85_000194"
     CDS             complement(38248..39753)
                     /gene="adcA"
                     /locus_tag="VYP85_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1880764.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(39763..40569)
                     /locus_tag="VYP85_000195"
     CDS             complement(39763..40569)
                     /locus_tag="VYP85_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1880765.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(40562..41266)
                     /locus_tag="VYP85_000196"
     CDS             complement(40562..41266)
                     /locus_tag="VYP85_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1880766.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(41266..41706)
                     /gene="adcR"
                     /locus_tag="VYP85_000197"
     CDS             complement(41266..41706)
                     /gene="adcR"
                     /locus_tag="VYP85_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1880767.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(41861..43129)
                     /gene="dltD"
                     /locus_tag="VYP85_000198"
     CDS             complement(41861..43129)
                     /gene="dltD"
                     /locus_tag="VYP85_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1880768.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNKRFFSKDWATYDGDVKEFQ"
     gene            complement(43122..43361)
                     /gene="dltC"
                     /locus_tag="VYP85_000199"
     CDS             complement(43122..43361)
                     /gene="dltC"
                     /locus_tag="VYP85_000199"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1880769.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(43375..44619)
                     /gene="dltB"
                     /locus_tag="VYP85_000200"
     CDS             complement(43375..44619)
                     /gene="dltB"
                     /locus_tag="VYP85_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1880770.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVIT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(44616..46166)
                     /gene="dltA"
                     /locus_tag="VYP85_000201"
     CDS             complement(44616..46166)
                     /gene="dltA"
                     /locus_tag="VYP85_000201"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1880771.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(46187..46318)
                     /locus_tag="VYP85_000202"
     CDS             complement(46187..46318)
                     /locus_tag="VYP85_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1880772.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(46549..47253)
                     /locus_tag="VYP85_000203"
     CDS             complement(46549..47253)
                     /locus_tag="VYP85_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1880773.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(47323..49149)
                     /gene="glpO"
                     /locus_tag="VYP85_000204"
     CDS             complement(47323..49149)
                     /gene="glpO"
                     /locus_tag="VYP85_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1880774.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(49191..50699)
                     /gene="glpK"
                     /locus_tag="VYP85_000205"
     CDS             complement(49191..50699)
                     /gene="glpK"
                     /locus_tag="VYP85_000205"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1880775.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(50858..52285)
                     /locus_tag="VYP85_000206"
     CDS             complement(50858..52285)
                     /locus_tag="VYP85_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1880776.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            52450..53322
                     /gene="hslO"
                     /locus_tag="VYP85_000207"
     CDS             52450..53322
                     /gene="hslO"
                     /locus_tag="VYP85_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1880777.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            53309..54289
                     /gene="dusB"
                     /locus_tag="VYP85_000208"
     CDS             53309..54289
                     /gene="dusB"
                     /locus_tag="VYP85_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1880778.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(54519..56426)
                     /gene="pspC"
                     /locus_tag="VYP85_000209"
     CDS             complement(54519..56426)
                     /gene="pspC"
                     /locus_tag="VYP85_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1880779.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGN
                     NSTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNADFNKKLSKIKTKYLY
                     ELNVLEEKSEAELTSKTKETKEELTAAFEQFKKDTLSTEPEKKVAEAKKKVEEAKKKA
                     EDQKEKDRRNYPTITYKTLELEIAESDVEVKKAELELVKVKANEPRDEEKIKQAEAKV
                     ESKQAEATRLKKIKTDREQAEATRLENIKTDREQAEEEAKVKDEPKKRTKRGVLGEPA
                     TPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYP
                     TNTYKTLELEIAESDVEVKKAELELVKEEAKEPRNEEKVKQAKAEVESKQAEATRLEK
                     IKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENPA
                     EQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYF
                     YNTDGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSW
                     YYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDS
                     YRVNANGEWVN"
     gene            complement(56505..57032)
                     /locus_tag="VYP85_000210"
     CDS             complement(56505..57032)
                     /locus_tag="VYP85_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1880780.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(57115..58455)
                     /gene="hk06"
                     /locus_tag="VYP85_000211"
     CDS             complement(57115..58455)
                     /gene="hk06"
                     /locus_tag="VYP85_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1880781.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(58452..59105)
                     /gene="rr06"
                     /locus_tag="VYP85_000212"
     CDS             complement(58452..59105)
                     /gene="rr06"
                     /locus_tag="VYP85_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1880782.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(59426..61858)
                     /locus_tag="VYP85_000213"
     CDS             complement(59426..61858)
                     /locus_tag="VYP85_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1880783.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(61860..62318)
                     /locus_tag="VYP85_000214"
     CDS             complement(61860..62318)
                     /locus_tag="VYP85_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1880784.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(62437..63165)
                     /locus_tag="VYP85_000215"
     CDS             complement(62437..63165)
                     /locus_tag="VYP85_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1880785.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(63165..64172)
                     /locus_tag="VYP85_000216"
     CDS             complement(63165..64172)
                     /locus_tag="VYP85_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1880786.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(64211..64969)
                     /locus_tag="VYP85_000217"
     CDS             complement(64211..64969)
                     /locus_tag="VYP85_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1880787.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(64932..65222)
                     /locus_tag="VYP85_000218"
     CDS             complement(64932..65222)
                     /locus_tag="VYP85_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1880788.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(65293..65395)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(65478..66824)
                     /gene="cbpD"
                     /locus_tag="VYP85_000219"
     CDS             complement(65478..66824)
                     /gene="cbpD"
                     /locus_tag="VYP85_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1880789.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKPEPLASGTVIDYYYPG
                     EKVHYDQIFEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGENVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSHSSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGLWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(66913..67179)
                     /locus_tag="VYP85_000220"
     CDS             complement(66913..67179)
                     /locus_tag="VYP85_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880790.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(67181..68533)
                     /gene="dnaB"
                     /locus_tag="VYP85_000221"
     CDS             complement(67181..68533)
                     /gene="dnaB"
                     /locus_tag="VYP85_000221"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1880791.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(68577..69029)
                     /gene="rplI"
                     /locus_tag="VYP85_000222"
     CDS             complement(68577..69029)
                     /gene="rplI"
                     /locus_tag="VYP85_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1880792.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(69026..70999)
                     /locus_tag="VYP85_000223"
     CDS             complement(69026..70999)
                     /locus_tag="VYP85_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1880793.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(71135..71683)
                     /gene="raiA"
                     /locus_tag="VYP85_000224"
     CDS             complement(71135..71683)
                     /gene="raiA"
                     /locus_tag="VYP85_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1880794.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(71755..72417)
                     /locus_tag="VYP85_000225"
     CDS             complement(71755..72417)
                     /locus_tag="VYP85_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1880795.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQYCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(72414..73712)
                     /locus_tag="VYP85_000226"
     CDS             complement(72414..73712)
                     /locus_tag="VYP85_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1880796.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            73768..74403
                     /locus_tag="VYP85_000227"
     CDS             73768..74403
                     /locus_tag="VYP85_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1880797.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            74688..75608
                     /gene="cysK"
                     /locus_tag="VYP85_000228"
     CDS             74688..75608
                     /gene="cysK"
                     /locus_tag="VYP85_000228"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1880798.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(75805..76203)
                     /locus_tag="VYP85_000229"
     CDS             complement(75805..76203)
                     /locus_tag="VYP85_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1880799.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEIANWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            76194..76502
                     /locus_tag="VYP85_000230"
                     /pseudo
     CDS             76194..76502
                     /locus_tag="VYP85_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(76693..76980)
                     /gene="tnpB"
                     /locus_tag="VYP85_000231"
     CDS             complement(76693..76980)
                     /gene="tnpB"
                     /locus_tag="VYP85_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1880800.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(77226..78266)
                     /locus_tag="VYP85_000232"
     CDS             complement(77226..78266)
                     /locus_tag="VYP85_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1880801.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(78345..79124)
                     /gene="rpsB"
                     /locus_tag="VYP85_000233"
     CDS             complement(78345..79124)
                     /gene="rpsB"
                     /locus_tag="VYP85_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1880802.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            complement(79348..80526)
                     /locus_tag="VYP85_000234"
     CDS             complement(79348..80526)
                     /locus_tag="VYP85_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1880803.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            complement(80620..81114)
                     /gene="mreD"
                     /locus_tag="VYP85_000235"
     CDS             complement(80620..81114)
                     /gene="mreD"
                     /locus_tag="VYP85_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1880804.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            complement(81114..81932)
                     /gene="mreC"
                     /locus_tag="VYP85_000236"
     CDS             complement(81114..81932)
                     /gene="mreC"
                     /locus_tag="VYP85_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1880805.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            complement(81991..82785)
                     /locus_tag="VYP85_000237"
     CDS             complement(81991..82785)
                     /locus_tag="VYP85_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1880806.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKSMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            complement(82778..83617)
                     /locus_tag="VYP85_000238"
     CDS             complement(82778..83617)
                     /locus_tag="VYP85_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1880807.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            complement(83602..84429)
                     /locus_tag="VYP85_000239"
     CDS             complement(83602..84429)
                     /locus_tag="VYP85_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1880808.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVVLRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSHNGYNLPENYLTESELEDKLWELL"
     gene            complement(84426..84971)
                     /gene="pgsA"
                     /locus_tag="VYP85_000240"
     CDS             complement(84426..84971)
                     /gene="pgsA"
                     /locus_tag="VYP85_000240"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1880809.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            complement(84982..85803)
                     /locus_tag="VYP85_000241"
     CDS             complement(84982..85803)
                     /locus_tag="VYP85_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1880810.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            complement(85845..87128)
                     /locus_tag="VYP85_000242"
     CDS             complement(85845..87128)
                     /locus_tag="VYP85_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1880811.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLIVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            complement(87125..88375)
                     /locus_tag="VYP85_000243"
     CDS             complement(87125..88375)
                     /locus_tag="VYP85_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1880812.1"
                     /translation="MELVHGISTHFIQSKKFKTHKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIVKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            88534..88902
                     /gene="yaaA"
                     /locus_tag="VYP85_000244"
     CDS             88534..88902
                     /gene="yaaA"
                     /locus_tag="VYP85_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1880813.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            88905..90002
                     /gene="recF"
                     /locus_tag="VYP85_000245"
     CDS             88905..90002
                     /gene="recF"
                     /locus_tag="VYP85_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1880814.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLNFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(90053..91531)
                     /gene="guaB"
                     /locus_tag="VYP85_000246"
     CDS             complement(90053..91531)
                     /gene="guaB"
                     /locus_tag="VYP85_000246"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1880815.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(91683..92708)
                     /gene="trpS"
                     /locus_tag="VYP85_000247"
     CDS             complement(91683..92708)
                     /gene="trpS"
                     /locus_tag="VYP85_000247"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1880816.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            92914..94536
                     /locus_tag="VYP85_000248"
     CDS             92914..94536
                     /locus_tag="VYP85_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1880817.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            94598..97150
                     /locus_tag="VYP85_000249"
     CDS             94598..97150
                     /locus_tag="VYP85_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1880818.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(97251..97565)
                     /locus_tag="VYP85_000250"
     CDS             complement(97251..97565)
                     /locus_tag="VYP85_000250"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1880819.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(97593..97931)
                     /locus_tag="VYP85_000251"
     CDS             complement(97593..97931)
                     /locus_tag="VYP85_000251"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880820.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFFAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            complement(98016..98783)
                     /locus_tag="VYP85_000252"
     CDS             complement(98016..98783)
                     /locus_tag="VYP85_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1880821.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            98961..99503
                     /locus_tag="VYP85_000253"
     CDS             98961..99503
                     /locus_tag="VYP85_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1880822.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(99544..99617)
                     /locus_tag="VYP85_000254"
     tRNA            complement(99544..99617)
                     /locus_tag="VYP85_000254"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(99581..99583),aa:Asn,seq:gtt)
     gene            complement(99623..99694)
                     /locus_tag="VYP85_000255"
     tRNA            complement(99623..99694)
                     /locus_tag="VYP85_000255"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(99659..99661),aa:Glu,seq:ttc)
     gene            complement(99746..100498)
                     /locus_tag="VYP85_000256"
     CDS             complement(99746..100498)
                     /locus_tag="VYP85_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1880823.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(100495..101820)
                     /locus_tag="VYP85_000257"
     CDS             complement(100495..101820)
                     /locus_tag="VYP85_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1880824.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(101841..101966)
                     /gene="comC"
                     /locus_tag="VYP85_000258"
     CDS             complement(101841..101966)
                     /gene="comC"
                     /locus_tag="VYP85_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1880825.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(102131..102204)
                     /locus_tag="VYP85_000259"
     tRNA            complement(102131..102204)
                     /locus_tag="VYP85_000259"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(102168..102170),aa:Arg,seq:tct)
     gene            complement(102248..102727)
                     /gene="rlmH"
                     /locus_tag="VYP85_000260"
     CDS             complement(102248..102727)
                     /gene="rlmH"
                     /locus_tag="VYP85_000260"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1880826.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
BASE COUNT        30980 a        22245 c        17838 g        31732 t
ORIGIN      
        1 taaattttaa gtcaaggaaa attaacccac tttaatttct tttttaaccc gggttaaaaa
       61 agaaattaaa gtgggttaaa aaagaaatta actgagtaaa aactctcgaa attcaattcg
      121 ctatattatc actcaacttg aacaaatacc agaaccacaa aaaacagatg taaaggaaaa
      181 atatggactt aaaatttgaa ggggttgatt tagaatacaa aaaagctaaa aacaatcttc
      241 cagagtcttt ctgggaaacc tactcagcat ttgcaaatac aaatggcggg aaaataattc
      301 tcgggataga tgaaaaaaac attgacacct accaaagagt caatagactc cctgcgaaat
      361 tatgaagcaa gtaaacaact aaccgatgca cgatttaagc gtcttgttgg tgttcagcgc
      421 accacttttg aagagatgtt agctgtgtta aaaacaactt atcaacttaa acacgcaaaa
      481 ggtggacgaa aacctaaatt aagcctagaa gaccttctta tggccactct tcaatatgtg
      541 cgagaatacc gcacttatga agaaattgcg gctgattttg gtattcacga aagcaactta
      601 atccgtcgga gccaatgggt tgaagcaact cttgttcaaa gtggtgttac gatttcaaga
      661 actcctctca gttctgagga cacggtaatg attgatgcga cggaagtaaa aatcaatcgc
      721 cctaaaaaaa gaactagcga atgattctgg taaaaagaaa tgccacgcta tgaaggctca
      781 agcgattgtc acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca
      841 tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc
      901 tgacagtggt tatcaagggc ccatgaagat atatcctcaa gcacaaactc cacgtaaatc
      961 cagcaaactc aagccgctaa tagctgaaga taaagcctat aaccatgcgc tatctaagga
     1021 gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatat tttcaacaac
     1081 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa
     1141 tcatgaacta ggattctagt tttgcaggaa gtctattgaa atactaagcc tacacacaga
     1201 ctgattccaa ttgtttttta gatttcaatt ttaccattct tcatagtcaa aaccatcata
     1261 atctggatat tgttctggcg acgttccaac cgaacgtacg agataagctt cttcgtcctc
     1321 tgtctcgatt tctctcagca cttggcattc aaaacgccat tcatcaccga agtcgaaaat
     1381 aaacttaaat ttttgtttga cacttaggct atccagatag acattttctg tgtaacgttc
     1441 ttcaacatcg tcactaacaa agctaagaaa gtaagaatct gcatgactcc actcaacatt
     1501 atccatgaaa aatgtgtgag catgatcatt tgcaaaatca aaactccata aaatcacatc
     1561 tgctagttcc gctaacgttt ttgtttttgg aatctatata tgtcggtagc aacctttttt
     1621 aaatttgacg gaaatgatcc aagcttctac agatgctggc ttttcagctt ctatttcttg
     1681 ttttactaat tttaagtgta gcataatacc tccaattgct catcgataga attgctctta
     1741 ggaaacattc actttctgct attttatcat aagtttgtct aactgtagca tttgaaacca
     1801 gataattctt ctgtttcacg cgaaacaccc tgcgccaagc aaggtgttct tgtttttata
     1861 ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa aacactgttt
     1921 tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta ttaagtcgta
     1981 taaatcgtcg acgctgtcgc aatggtatgc cactggttgg ctgtagttgc tgcgaaatcc
     2041 ttgtctgcgt agaagtcagt aaatggtagg atttcaactt ccagctcgtc gatgcggtca
     2101 agctgaccag ccagataaaa ctcgatacgg ctttctgctc gtttgatgcg ttgcaagagt
     2161 ccgcccatac ggatgtcaac tgtatccaaa ccaaagacct tgttttcttt cagccattgg
     2221 tgactaaaga gggcatggaa gtcttcaatt tggcttctaa gttctggtaa ttcttgtctg
     2281 gcgatttgtt gtaaactttc tttatcatcc gcttggtagg cctgacgaat gcgtcgtccc
     2341 acatctactt tgctacttaa aatagcattc aactgggcct gagtttcaaa gagataggca
     2401 tagtttccag ctttttcttt aatgttagca agcgtctcag cagcctgagc gaagtgcggt
     2461 ttgtcctgtt caggtgtcat gtgttgatca agaatcggac aaagaatatc ctgataaaaa
     2521 acatagcggt tgggattgat accgctgaga ttgcctggta ggtctggtaa gaggttggca
     2581 aggtcaatct gcataaaatc ctcaaccgtt agaccagtat tggtcttgaa gtgcgcagac
     2641 aaaccatcta ggtcattgcg atagctgagt tctgcccaga tttgcaagct tggtaggata
     2701 gagaactggg cagtttcacc accattgtct ccccaacccg ttacgatgac ttctttaatc
     2761 tgattggcac ggcaggcttt attagcctcg atagccacta gacggctaaa atggttgtga
     2821 ggtgtaaagc caatccactt ccaagctccc cctgcaaatg caaggtcatg gctaatcttg
     2881 tgatgattgc ggaaattacg gttgtatttt tcctcgctat cctgataata atcccagtaa
     2941 accagagtca cacggtcttt gagacggtct aggtagacac gagtttcctc tggaatttcc
     3001 acatcacgat cgtactggcc atccgctgac atgagtttga agaacatatc actccacatc
     3061 tggcagtgga aaccatattt gtcagcaata tccagcacgc gctccaagtg ttggcacatg
     3121 aggagactac gatccacaac accgttcaaa atcaggtagc gtcccaaacc aaccaagtgg
     3181 gcttcgtcca tcccgatatt gaccttgcga gtcttcagtt tagacaacgt ggcaaacatg
     3241 ccatcaatca ggtcataaac cttttcttcg ccaatgagaa gaatgtcctc tacatcacgg
     3301 agctcctgca cttccttgac accccatttg acaaaggccg acaagtgggc caaggtctgg
     3361 atgcatggta caaaggtcat gtcaaactgt tgagcatagg cttctatttc ctgcaactcc
     3421 tctgctgaat aagctccacg gaaatagcca aagtaaggct gtccttcaat ctggtaagtg
     3481 tcttccatgt aaagctcaaa ggttgagtag cccatgagag ccaagacctc aatcatctgc
     3541 ttggcagaag ccacattcag caccgcattt cgagaacagt caaccatgta agccaaatct
     3601 tcgtaagctg cttgttcctc aatctctact ttatcagctt ctgctagaac tgttaccaac
     3661 aaggataagg cacgataaag ttggtgaggt ttgcggtagg tcaattgata gtgaccttcc
     3721 tcaccctcga tagagataga ggcttggtca gactgagtga cagccacttc cacatctggt
     3781 agagaaatat gaccttttaa aacctcaata gcttgcgttt gtttgggact aagtcctgta
     3841 aatcttacca ttgcttttcc tcctgtagcc agttgacaag agcaccgtag agattggcat
     3901 ctgcgtgata ggtgcaggcc tggataactg gtgcgaccgt gtattcttcg taggtatcga
     3961 caaagttatc aacagccttc ttgacatctt ggataaaatc tggattttga ctgatagagc
     4021 cacccagact gatgacatct ggatcgatga gatactggat attgagcaag ccttgcgcca
     4081 gattgcggtt catgcgctca atggcttctt gacaaagagc attaccagct gcggcctctt
     4141 ggtaaatctt gcgaccgtcc caatcagtat gaccagattt ttcaatcacg tatcgtacca
     4201 tattcccagt tgatgctagt tgcgaccagt tattaagttt ttcagcaggg gcaagggttg
     4261 tcatgtagcc aaattctcca cccaagccgt ggcgacctcg atgaagtcta ccattgataa
     4321 tcatggctcc gccaatccct gtcccaatca cgacacaggc tgcattttca agatctggat
     4381 gagctagtag ttcactgagt ccaacgcagt tggcatcatt ttctaaatgg acaggtagct
     4441 gataagagct aagcgcctca taccaagaaa agccatggat gtagggcacc gcactgaagc
     4501 catcaatcac acctgtctct tgattgactg cacctggaac gctcatagca atcccactgt
     4561 aatcctgttc tgacaagcgt tgatctagcc acgctagtaa atcctccaag ttttcaggcg
     4621 ttgaaatact tgtcttatcc agtattttcc catcaggagt cagactggca aacttaatcc
     4681 cagtccctcc gatatcaatc gttgcaatgg tcattgtttt taccataaaa aggggcgaat
     4741 cagcagttag ttcttacttt ttcgcccctc ctttcttttg atgtttactt tttgaaatta
     4801 aatttcttct tttttgatga attctgtacg aatctcttgt ggatccaatg gtcctgaatg
     4861 aactggatat ggtcgctcaa gtaagtcaag aatggtttgt tgatgttctg atatgtgcac
     4921 attttcttga ctcatattat agtaacggaa gacatagcct tcttcatttt ccgccacttt
     4981 aaaggctgtt ggacaaactt gcggtatgct gagaacagaa tggctcaaga ggctaccagt
     5041 cgcaaccacg cttccttcct gtctagcaag ctgaaggctg gtaaacggtg tctgcaaggc
     5101 tttggcacga cggaaagctg aaaagcgttc ttgggcttgg tggcattcaa gtgcaaactc
     5161 gacttcaaac tcacgcaagc attgtgcttc tggcgttggg aagtagcccc agtcacctag
     5221 ctcacctgat gcacgcaaaa tggtcacggc aatggtgtta tccccaagga tttcgtattc
     5281 attcaatccc ttattggata cagtcacccc tttttcatcg tcatacagac tgacaaaagc
     5341 ttgttggtgt tgaggatttt caggattttc ccatgaagca gctggtttgt ttggtcgtgt
     5401 caccacctca tagatacttt cagaatcatt gcttggacgc gtgttatgag tcttgaccaa
     5461 gagacggata cggtgatcct tggcagtgtt agtaaagcga gtcttgaagc ggatttgtgg
     5521 attgtcaacg aagacagtca actcagtttc cagaggaatg tttgtcaatt cttctgaccg
     5581 tccagcctca cgcttcataa actcgatgat accttgttgc tcttcttcta gcttttcatc
     5641 cgcactgaca ggcacggtca attcatgttt gagcaagatt ttagcatagc gatctgtgtt
     5701 ttccaagacc tcgtggccct taagctctgc aaagattggc tctgttcctt ttggttggaa
     5761 atagatatac tcgtttccga tgtcaccccg gtcttcgaag cggataaagt cttcataggc
     5821 ttcgtgagtt gtcttgtcat atactgtgat attgtcatcc acactcaccg ttacgaatgg
     5881 tgtatcaatc actccgtttt ggtaaatacc ctcacggtgt tcttgttttc cttccagcaa
     5941 ttggaaggtt gtccaagaaa gcggcgctag gtgaactgga atggtcacgc gcacttgtcg
     6001 agcaatacga gcttggcgga acttgtcttt tggtaaatcg tactcaaaat tagctccgag
     6061 gtcttcgatt gtagcctcta caggacgacc atccaagtcc tccacacggt aacttggtaa
     6121 gataagagca gccatctttt tgtagccttc tgttgggtgc aattccttga aatcacaagt
     6181 cgccacatca atcactgtgc tgacagtatc gaccttatca tgcaagcctg tgttaatgac
     6241 agtaaagaga tagtcacttt gagccttatc cgtagcaatt ttacccttcc actcgttgag
     6301 caagttactt ttaacaaagt ttcctacttg gttgaccttg gcaaaacgcg tttccatctc
     6361 gcggtgaact tcgtccacgc tacagccaca gatactatca tgtggcgcat tctgcaaaag
     6421 tgttttccaa gcataggtca actggtcctt gtggttgtgt ccaccagtga taatagtcaa
     6481 gggttctacc acttgctcta ggaggttgct attttcttgg aaggcttgtt ttaggtaaat
     6541 gcgggatgaa gaagtgttgg caagtgtgta ccagccatct gtttcctgac tggtcaactc
     6601 gcctgtaaca gttgataagt gttcaggaag cgcaccttct acagcttgaa catattcatc
     6661 aaaagaacta tgaacaaaga ttacatccgg gaagagttca tttgccacac gaatggcttc
     6721 gctcagattt ttctgtacag gctggtggtc acagccgttc atcatcaacc attggttggt
     6781 cgaagcgtag gcacgcacat ctgacaattt ttgtttccag aaggtcaagg cctcatcttt
     6841 gtcaactggg atttcattcc cattactgta ccagttggca aagagaatac ctaaaacacg
     6901 actaccatcc acaccctgcc agtacatttc tgaaaactgg gatgtaaacc gctcatcttc
     6961 aaggacttgg ttgtcaaatc caatcggctt cacaccacga ccaaaggctg ccacgtgaat
     7021 acctgatttt tgaaggattt gaggagcttg tcccatattt ccaaaggtat ctggaaagta
     7081 gccaatctgg gttgatttac cccatttggc agcttcttgt tgaccaatca aggtattgcg
     7141 gacattggct tcactggaga tcaaataatc atcctgcaag atgtaaaagg gaccaatttt
     7201 aagcttgccc tcgtcaatgt agcgttggac cttgtcacga ttttcagggc gaatttgtaa
     7261 gtagtcgtca aggacaatag tttgtccatc caagtggaaa ctcttgaact cagggtcatt
     7321 ttcaaagaga tcaaagagat tgtcaaacaa ttccaccaac tgcatacgat gactttcaaa
     7381 aggcaagtac cactcacggt cccagtgact atgtgagata atatgtacaa caacattttc
     7441 catgaagtaa aacctcattc taaatttaaa ttttaacgtt ttaaatgtaa acttgtgatt
     7501 ctgataagaa tcggttgagc taaagcgagc cccttagcga atatccaagt aatccaagac
     7561 caactcacag aacatcatgt tagcccagga gaaccattca cgagagtaga gggtcggatc
     7621 atctacatga aagctttcgt gcatgacacc tgtaccacca tcgcaggcaa ccagctgatc
     7681 cagcaagaat tttttctctg ccttatctct tgttgtcaag ccttggatag aaagggcgat
     7741 tggccagata tagcgataga aggtatgaga actgccgaga ccgcttgcgt attctccttg
     7801 gtagaagtat ggattttcag agctcaaaat ggtacgacga gtagcttgat acacttcatc
     7861 atcgaccgaa cagtagccca gatagggcgc agctagtaga cttggtacat ttggatcatc
     7921 catgatgctg gcatttccta ggccatccac ttcaaaagcg taaatctttt cgcccttgct
     7981 gttggtggtg taagcgtagt ttttgattcc ttcttggatt tcatcctgaa gacgcttggc
     8041 atcagcaata acactctggc tatcagctag gtttaatgct gcgaagattt cttgcacata
     8101 acccaagact actacagcaa acatatttga cggaatcaag taactatact ggcaacagtc
     8161 atcactcgga cgaaaagctg accaagtcat acctgtcact gcaaagtcag gtccaaagcc
     8221 atcatttacc aaggtgtctt ccttacggtc cgtatctcgg acaaaacgat aaggagagtt
     8281 cttgtggtct tgttccaccg tccacagatg gagaatttcc ttagtcgctg cgacaaaaat
     8341 ctcatcaaac tgactagtct cgccagtctc tttccagagg agataagcca actgcaaagg
     8401 atagcaaagc gaatccacct catacttgcg ctcccagatc cagccgttaa ggtctgtgtg
     8461 gtcagtctcg tggtgccctt tccagttctc ctcaatgttg aaggagttag catagggatc
     8521 cttgagtacc aaggtcatct gacgtttgac caaacctgca atggtctgac gcaggagggc
     8581 atctctttta gctacatgaa ggtagggtct gagttgggct gtcgaatctc gaagccacat
     8641 ggcaggaata tccccagtca agacaaaagt tgaaccatct tctaagattt caaccgtatt
     8701 gtccaaggta tcggtgtagc aacgctcgaa aacatccacc cactctggat agtccttagc
     8761 ccgctctgct acttcatcta gccactctct gacgatttct ttcgaataaa ccattttaaa
     8821 ttttacctct ttcaaacaag tttcatgttc agtatatagc ttttgagaca gaaaatacat
     8881 acacaaatga tagtcatttt tctacaaaat agttattttt gaaactcctt ttctaaaggc
     8941 cctctttttc tgatataatg tagaaaaaca gctaaaggaa agactatgaa accactactt
     9001 gaaaccatcg atacccgctt tggaactacc aacaagcatg ccttttctcg gggaaatacc
     9061 ctgccataca caggcgtgcc ttttgggatg aattactttg tgccccagac cagtgaccag
     9121 gatggatctt ggttttttga tccacatctg cctatctttc aggggattcg attaactcac
     9181 cagcccagtc cttggattgg ggactactct tggctccttc tgacacctgt caccagtcaa
     9241 ctgggtggag acagcctctt tcaccgccaa tcttcctatg atagggataa ggcctctttc
     9301 caacctcatt atctaaagat tttctccctg cgctatcaga ttgaaaccca gctcacaccg
     9361 acttgctacg gtgcttctat tcgtttgaag caaaagcaag gcaaagccct ctccctctat
     9421 cttcacgcaa cagatgaact gacagtagag caagtagata agcgaactct tgccctgcaa
     9481 caagaaggta aaactgaaac taacaaaaat tcgctaacga tgttcactgc cctgcaaatg
     9541 aacacggata ttcttgctat cagccaagaa gctggagact ggcgaattga cttagcaagt
     9601 agtcaaaccg agatgcaact agccacttct ttcatctctc cttctcaagc tctaatcaat
     9661 ctacctcaag aagattttga tagctgtaaa acaagtgccc aagcggattg ggaaaatctc
     9721 ctccatcgtt ttgacattat agagacagga gaggctgacc gaaccttctt tgaccactgc
     9781 ctctacagac tcttcctctt cccacagact ttttatgagg ttgatgagtc agggcaagcc
     9841 atccacatgg atctggctac tggtactgtc aagcctggtg tcctctttag caacaatggt
     9901 ttctgggata ccttccgcac caccttcccc ctctttgccc ttatcatacc ggagcactat
     9961 caacgctttt tagaaggttt cctcaatagc taccgcgata ctggtttcct tccaaaatgg
    10021 ctggctccag atgaacgggg tatgatgcca ggtacacttt tagacggtat tatcgcagat
    10081 agcgcctgca aggacatggc ccccgaccta gaaggagaac tcttccaagc catgctcaaa
    10141 acagccagca aagccgaccc tctcggcatc aatggccgcc acggactagc ccaataccaa
    10201 gaactagatt acctctctac cgaccaccac gaaagtgtta gccatactct agactatgcc
    10261 tatagtgact tttgtatcgc caactgtgcc aaaaaactaa aaaacataga aatcgctgaa
    10321 acctacaagg ctgcttcaca aaattaccgc cagctatttg acgctgagac aggttacatg
    10381 cgagcacgag acaatcaagg aaactttcac cctgacttct ctccttatag ttgggggcga
    10441 gactacgctg aatgctctgc cattcaagct actttaggcg ttctccacga catccctggc
    10501 ttaatccaac tgatgggtgg aaaagaaacc tttagcaact atcttttgaa agcctgtcaa
    10561 gatgctcccc tctttgaaac aacaggctat ggttacgaaa ttcacgaaat gagcgagatg
    10621 gctactgctc cttttggaca gatagccatt tccaaccagc ctagtttcca cattccttat
    10681 ctcttccgct acagcgatta ccctgactac actgcccttc ttatcaagac gctccgtcag
    10741 aaagcttttc acccaagttg ggaagcctat cctggagatg aagacaatgg tagtctctct
    10801 gcttggtaca tctggtcagc tctcggattt tatccaacct gtccaggaaa accaagctat
    10861 gacctcggaa tctctctctt tgaccatcta cgagtctacc tcgctaaaga agataaatgg
    10921 ctggatatcc atactaaaca aaaccacaac cattttaact ttgtcaaaga atgccgactg
    10981 gacaaaacac tcgtatcaac tattcaacac caagacctct taaaagctga acaactaact
    11041 ttcaccctca gctggttacc aagtcattaa taaccaaaag aacctttgca tcgcgcaaag
    11101 gttcttcttt tatgaaactt ggacttgaag ttgatccaca agctgaccat ccaccgttag
    11161 gttcagatag aaatccaagg ttttatctcc tgcgaaatac agggttggta gatgcaaatc
    11221 ttttttgctt tcccctgctt ggaattgaag aacttgaatc tcatcctgat aggcgacacc
    11281 atggacacct gtccccggtt gaatcgaaat cttagcctct aaagaggagc tactttcact
    11341 acgttcaatc ctaaaatgaa gagtctctcc ctttgccaca gctaggcttt tttctgcaaa
    11401 tgctagttcc tgaacaactt ctttttttga taatccagga gttttataaa gggaaatctt
    11461 ggtcagtaga ggcatagatt gtgcttcggt aatcatcacg cgcaccttct gtgcctctac
    11521 tagcggacct cgcaagaggc gcttatgacc aactgtgaag cccctgccaa attcctgcca
    11581 gacaccatcc acctctactt gcacatggaa agcagaaata cgttggccta acttcaaatc
    11641 ttctctcaac tcaattacat caaaagtttt aggagaacct aagtcgagtt ctaactggat
    11701 gggcaagtct gcatcgtttg cccaagagct ggtctcaagg ccgtctgtca aatggcgaca
    11761 agcaaagtct gcggaaagag ctggaccaga tacctcagct cccagagcca aatcttcttt
    11821 atagagctca ttgcgatagg tcgcaaattc ataaagtcgt tcaatatcct ttgcatcaaa
    11881 gagcccagct tgattcggcg gaatattaag caagagtgga gttcctcgcc ctactgagtg
    11941 aaagtagatt tcgaccaact cctcgagaga cttaggatcc tgatcctcat ggtagaacca
    12001 gcctggacgg atggaaacat ctgcctctcc gattgaaaaa atcgtgcccg agggatcccc
    12061 gtgctgaaga tagttcagct ctgcttctgt tcctagttta tcaggattca ccttttgcca
    12121 cagtggatca cctgcatacc ctcgttcatt gccaatccag cggatactgg tgccttctgt
    12181 tgaaaaaatc aagcaatcgc cctgcaggtc acgaatggtt tcaaaccatt tttcaaattc
    12241 ataattaacc ttttgcgcgc cctctcctct ggcaccatcc atccaaacct cagcgaactt
    12301 accagcattc ccatagttag gatttgataa gatttccttc aactgagcca gataataggc
    12361 attgtagtcc gcttctcggt ccacatgata gaggggacta tgggcatccc acggtgacag
    12421 gtagaccccc atatccatat caaactctgt ggcagcttgg gatacttcaa ggagcaagtc
    12481 gccctttcct ctcctccaag gactgacctt aaccgaataa tctgtgtgag ctgtcggata
    12541 aaggacaaag ccatcgtggt gcttgaccac caaaatcaac tttttgaagc ccgtttcctt
    12601 gagcacacga acccactcac gcgcatccaa ctgactcggg ttaaagcgct caggatcctc
    12661 ctgtccagtc ccccattctt ggtcataaaa ggtattagga ccgaagtgga taaaagctgc
    12721 tagttcatct cccagataag ctagctgagt ctgacttggt aacggtccat gcggtttgat
    12781 tttcttcatc gttatatatc tccttcttta gcaacttctc ttgttcacaa ggttatccac
    12841 aggttgtgga taataaaaaa tgatctaacc gccagctctt tccaactcca actggtaggc
    12901 tcaggatttt gctcctcaat gttccctctt caaacagctc tgtcatatgg ttctgctaac
    12961 acctctcaga atgctactct ccataattat tctcaggctt ctttcaggtc attgtgtgaa
    13021 gaccattcac tctccagact tttccacaga ttgtgaataa gtgattattc taaactatca
    13081 tctcgtcgac tataacaaaa aataaaaaga gggtcaataa gataattatc tcttcctaaa
    13141 tactcagaaa agattctata atttgtacaa ttgagcaaga aatgcttctc caaaatctat
    13201 cttcaaaaga atgttgcatc tttttatcct ttcacacaaa catttctctt tatacagatc
    13261 caagtgataa ccagatgata attggacact ttttggttat ttgtgtattt tttgaaaaat
    13321 tttttaaaaa aattttatat cctctttaat agaagtttat gcatttgtat atatatattc
    13381 catcctatgt tgtgtataat aacataaaat tgtgctaaat atcataattt atattatttt
    13441 ccgagaaatt atagccattg acattaccta ggaattgcgt tataacatac atgtaagcgg
    13501 tacccaaaat ggtgccaagt caaaattttt aaggaggaaa atacatgtct tcacatccaa
    13561 ttcaggtctt ctcagaaatt gggaaactga aaaaagttat gttgcaccgt ccaggcaagg
    13621 agttagaaaa cttgttgccg gactatcttg aaaggcttct ttttgatgat attcctttct
    13681 tggaagatgc tcaaaaagaa catgatgcat ttgcccaagc tcttcgcgat gaaggaattg
    13741 aggttctcta cctagaacaa ctcgctgctg aatcattgac ctctccagaa atccgcgatc
    13801 aatttatcga ggaatactta gacgaagcca acatccgtga tcgtcaaacc aaggttgcta
    13861 ttcgtgaatt gcttcacggc atcaaggaca accaagaatt ggttgaaaaa acaatggctg
    13921 ggattcaaaa agttgaattg ccagaaattc ctgacgaagc taaagatcta actgacttag
    13981 ttgaatcaga ttatccattt gcaattgacc cgatgccaaa cctctatttc actcgcgacc
    14041 catttgcaac aattggaaac gccgtatcgc ttaaccacat gtttgcagac actcgtaacc
    14101 gtgaaacact ctacggtaag tatatcttca aataccaccc aatctatggc ggaaaagtgg
    14161 atttggtcta caaccgtgaa gaagatacgc gtatcgaagg tggagacgag ctagttcttt
    14221 ctaaagacgt ccttgcagta ggtatttctc aacgtacaga cgcagcttct atcgaaaaac
    14281 ttttggtcaa catcttcaag aaaaatgttg gcttcaagaa agttttggcc tttgaatttg
    14341 ctaacaaccg taaattcatg cacttggata ctgtcttcac tatggtagac tatgacaagt
    14401 tcactattca cccagaaatc gaaggcgacc ttcacgttta ctcagttact tacgaaaacg
    14461 aaaaacttaa aatcgttgaa gagaaaggtg acttagctga acttcttgct caaaaccttg
    14521 gtgtagaaaa agttcatttg attcgttgcg gtggtggcaa tatcgtagca gctgcgcgtg
    14581 aacaatggaa cgacggttct aacactttga ccatcgcacc tggtgtggta gttgtttatg
    14641 accgcaatac cgtgaccaat aagattttgg aagaatacgg gcttcgcttg attaagattc
    14701 gcggaagtga attggttcgg ggccgtggtg gacctcgttg tatgtctatg ccatttgaac
    14761 gtgaagaagt gtaatcgctg ttcggcattc gtcaatagaa aatgtaaaaa atagaaagag
    14821 gaaataataa aatgacaaat tcagtattcc aaggacgcag cttcttagca gaaaaagact
    14881 ttacccgtgc agagttagaa taccttattg gtctttcagc tcacttgaaa gatttgaaaa
    14941 aacgcaatat tcaacaccac taccttgctg gcaagaatat cgctctccta tttgaaaaaa
    15001 catctactcg tactcgtgca gcctttacaa ctgcggctat cgaccttggt gctcacccag
    15061 aatacctcgg agcaaatgat attcagttgg gtaaaaaaga atctactgaa gatactgcta
    15121 aagtattggg acgtatgttt gacgggattg aattccgcgg attcagccaa cgtatggttg
    15181 aagaattggc agaattctca ggcgttccag tatggaacgg tctaactgac gaatggcacc
    15241 caactcaaat gctcgctgac tacttgactg ttcaagaaaa cttcggtcgc ttggaaggct
    15301 tgacattggt atactgtggt gatggacgta acaacgttgc caacagcttg ctcgtaacag
    15361 gtgctatcct tggtgtcaat gttcacatct tctcaccaaa agaactcttc ccagaaaaag
    15421 aaatcgttga attggcagaa ggatttgcta aagaaagtgg cgcacatgtt ctcatcactg
    15481 aagatgctga tgaagcagtt aaagatgcag atgttcttta cacagacgtt tgggtatcaa
    15541 tgggtgaaga agacaaattc gcagaacgtg tagctcttct taaaccttac caagtcaata
    15601 tggacttagt taaaaaagca ggcaatgaaa acttgatctt cctacactgc ttgccagcat
    15661 tccacgatac tcacactgtt tatggtaaag acgttgctga aaaatttggt gtagaagaaa
    15721 tggaagtaac agacgaagtc ttccgcagca agtacgctcg ccacttcgat caagcagaaa
    15781 accgtatgca cactatcaaa gctgttatgg ctgctacact tggtaacctt tatattccta
    15841 aagtataatt ttagataata aaccgtctac caacagctat gagggctgcg actaatagct
    15901 ttagtccggt cctcttttat gtaatggtaa tctattattt cttataaaat atgtgaaaaa
    15961 tcattaaatt gaaatctaaa cgcattctat tgagtgtgat aaaggagaat ttatggcaaa
    16021 tcgtaaaatt gtagtagctt tgggaggaaa tgcgattctt tcttctgacc catcagcaaa
    16081 ggctcaacaa gaagctttag ttgaaacagc taagcatctt gtaaaattga ttaaaaatgg
    16141 agatgatctg attatcactc acggtaatgg acctcaagtt gggaatctct tgctccaaca
    16201 tttggcatca gactctgaaa agaaccctgc cttcccactc gactcacttg tcgctatgac
    16261 agaaggtagc atcggtttct ggttgaaaaa tgctttgcaa aatgctctct tggatgaagg
    16321 catcgaaaaa aatgttgcct ctgttgtaac gcaagttgtc gtagataaaa atgatccagc
    16381 ttttgttaac ttgagtaaac caatcggtcc tttctattca gaagaagaag caaaagcaga
    16441 agccgaaaaa agcggagcga ctttcaagga agatgctggc cgtggctggc gtaaggtcgt
    16501 tgcctcacca aaacctgttg acatcaaaga aattgaaacc atccgtactc ttttaaataa
    16561 tggtcaagtc gtcgtagctg caggtggtgg cggtattccc gtcgtcaaag aaaacaatgg
    16621 acatttgact ggtgtcgaag cggttattga taaagacttc gcttcccaac gtttggcaga
    16681 attggttgat gcagacctct tcatcatttt gacaggtgta gattatgtat ttgttaacta
    16741 caacaagcca aaccaggaaa aattggaaca tgtgaatgtt gcccagctgg aagaatatat
    16801 caaacaagat cagtttgcac caggtagcat gcttccaaaa gtagaagcag ctatcgcttt
    16861 tgtcaatggt cgtccagaag gaaaagcagt tattacttcc cttgaaaatc taggcgcctt
    16921 gattgaatct gaaagcggaa caattattga aaaaggataa gttgttttac taataagatg
    16981 tattctattt ctagtatctt tatatcaaat tagaaattat tcttgaaaac atgtacaata
    17041 tttcaaaaga tactagtttt agactttaat atggtaaaac aaatataaat agaaagcgtt
    17101 ttcttgaatg tttatttaag aaagtagttg gttttttaca ctttgttaga catcaggagg
    17161 aaaaacaaat gagtgaaaaa gctaaaaaag ggtttaagat gccttcatct tacaccgtat
    17221 tattgataat cattgctatt atggcagtgc taacttggtt tatccctgcg ggggccttta
    17281 tagaaggtat ttacgaggct cagcctcaaa atccacaagg gatttgggat gtcctcatgg
    17341 caccgattcg ggctatgcta ggtactcatc cagaggaagg ttcgctcatt aaagaaacga
    17401 gcgcagcgat tgatgtagcc ttcttcatcc ttatggttgg tggtttcctt ggcattgtca
    17461 acaaaactgg tgctcttgac gtagggattg cctctatcgt gaagaagtat aagggccgcg
    17521 aaaaaatgtt aattttggta ctgatgcctt tgtttgccct cggtggtaca acttatggta
    17581 tgggggaaga aacaatggcc ttctatccac tccttgtgcc agttatgatg gccgttggtt
    17641 ttgatagcct gactggtgtt gcaattattt tgctcggttc tcaaatcggc tgtttggcat
    17701 ctactctgaa tccatttgcg acaggtattg cttcagcgac tgcgggagtt ggtacagggg
    17761 acggtatcgt acttcgtctg atcttctggg ttaccttgac tgctcttagt acttggtttg
    17821 tttaccgtta tgcggataag attcaaaaag atccgactaa gtcactggtt tatagtactc
    17881 gcaaagaaga tttgaaacac tttaacgtag aagaatcttc atctgtagaa tctacactta
    17941 gcagcaaaca aaaatcagtt ctcttcttat ttgtgttgac attcatcttg atggtattga
    18001 gcttcattcc atggacagac cttggcgtta ccatttttga tgactttaat gcttggttga
    18061 ctggtcttcc agttattggt aatattgtcg gttcatctac ttctgcacta ggtacttggt
    18121 acttcccaga aggcgcaatg ctctttgcct ttatgggtat cctgattggt gttatttatg
    18181 gtcttaaaga agataagatt atctcttcct tcatgaatgg tgctgctgac ttgctcagtg
    18241 ttgccttgat tgtagcgatt gctcgtggta ttcaagttat catgaacgac ggtatgatta
    18301 ccgatacaat cctcaactgg ggtaaagaag gcttgagcgg tctatcttca caagtcttta
    18361 tcgttgtaac ttatatcttc tatctaccta tgtcattctt gatcccatct tcatctggtc
    18421 ttgccagcgc aactatgggt atcatggctc cacttggaga atttgtaaat gtccgtccta
    18481 gcttgattat cactgcttac caatctgctt caggtgtctt gaacttgatt gcaccaacat
    18541 ctggtattgt gatgggagct cttgcacttg gacgtatcaa cattggtact tggtggaaat
    18601 tcatgggcaa actcgtagtc gctattattg tagtgaccat cgcccttctt ctccttggaa
    18661 ccttccttcc attcctataa aatagtgagt gaggtgattc catgaaaata gatataacaa
    18721 atcaagttaa agatgaattt cttatatcat taaaaacctt gatttcctat ccttcagtac
    18781 tcaatgaagg agaaaatgga acaccttttg gacaagcaat ccaagatgtc ctagaaaaaa
    18841 ctttagagat ttgtcgagac ataggtttca ctacctatct tgaccctaaa ggttattacg
    18901 gatatgcaga aatcggtcag ggagcagagc ttctggccat tctctgtcat ttggatgttg
    18961 ttccatcagg tgatgaagca gattggcaga caccgccatt tgaagcaact atcaaagacg
    19021 gctgggtatt cggacgtggt gtccaagatg ataaaggccc ttcgctcgca gctctctatg
    19081 cagtaaaaag cttgctggac caaggtattc agttcaaaaa gcgcgtacgc tttatctttg
    19141 gtaccgatga ggaaaccctc tggcgctgca tggcacgcta caataccatc gaagaacagg
    19201 ccagcatggg ctttgcacct gactcatctt ttcctctgac ctatgctgaa aaagggcttc
    19261 tacaggtcaa acttcatggc cctggatcgg atcaactaga gcttgaagta ggaggcgcct
    19321 ttaacgttgt accagacaag gccaactacc aaggtcccct ctatgaacag gtttgtaacg
    19381 atctcaaaga agctggttat gattaccaat ccactgaaca aaccgtaacg gttctcggag
    19441 tgccaaagca tgctaaggat gctagtcaag gtatcaatgc tgtcatccga ctagctacca
    19501 ttcttgctcc tctccaagaa caccctgctc tcagctttct tgcaacacaa gcaggtcaag
    19561 acggcacagg aagacaaatc tttggtgata tagcagatga accttctggt cacctatcct
    19621 ttaatgtcgc aggtctcatg atcaatcatg aacgttctga aatccgtatt gacattcgga
    19681 ctcctgtctt agctgataag gaagaactag tagagttgct tacaagatgt gcacaaaact
    19741 accaactccg ctacgaagag tttgactatc tagcgcctct atacgtcgca aaagacagta
    19801 aactcgttag cacactgatg caaatctacc aagaaaagac tggcgataac agtcctgcta
    19861 tttcatccgg tggtgccact tttgctcgca ccatgccaaa ttgtgtagcc ttcggcgcct
    19921 tattcccagg agcgaagcag acagaacatc aggcaaatga atgtgccgtt ctagaagatt
    19981 tgtaccgtgc tatggatatt tatgccgaag ccgtctatcg acttgcaact taatcaggca
    20041 actgtttcta ccaaaaaaaa atcgaccgat taatgaactg caccccaaaa gttagacaga
    20101 ataaatctaa cttttggggt gttttattat gaaattgagt tatgaagata aagttcagat
    20161 ctatgaacta agaaagcaag gacaaagctt caaacagctt tcaaaaagat ttggtgtgga
    20221 tgtttctggt ctaaagtcat ctgaatcttt gagatgagct ttataaatcg cttttttcag
    20281 tttttgcact ggtgtttcga taaactcaaa ctttttagcc gtggtattgc ctgattttat
    20341 agtatattga aactagaata gtacacctct acttctaaaa catttttaga aatcgatttg
    20401 actgtcctga tcgatttgtc ctgttcttat ttcattttac tatatttgag ccactttgtc
    20461 tttaacggct ttattcataa gctcttgtaa tttttcttta ctatcaatta cttctgattt
    20521 tccgttgtaa tttattgtaa taggttttaa cttacctaat ttctcgacac gctcattaat
    20581 ttgatctttt ttgaaggctg catatgtttt tcctaagatt ttttcgaaaa tatatttatc
    20641 agatagcggt ttgccttctt cttcagcttg gtttttgtat tgatttgaaa cataaggaac
    20701 aaatccttca tagtaaccta atgctcccat aagttcaaaa gcttgttttc taattcaaac
    20761 cattgcaact cagatttcag cttttcagat aaatcctgct catccaaata atgacttgaa
    20821 attagtgctg aactcgtttc tgtatcctgt acaggctgat cacccatacc agcaaaaaat
    20881 aaactcgttc ctagcaagac cgaacaagct cctattgcat atttcctcaa agaaaaacgc
    20941 tgctttctct caaattgaaa ttctttcatc ccatctccca tcattcatta ttactgtata
    21001 ttttgtatat cagaaatagt ttgtattcac aaatctttct agttattccc ttatcattcc
    21061 taattaaggg agataacata caataatttt tagttaaatg tatatcgatg ttttttgttt
    21121 ttcttaataa acgcaataca aaaagagcct gttgccaagc tctttgtact caatgaaaat
    21181 caaagagcaa actaggaaac tagccacagg ttgctcaaaa caccgttttg aggtagtaga
    21241 taagactgac gaagtcagct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt
    21301 cagtaacatc tatacggcaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat
    21361 tagtctatta tttcttctca gcgcgaaggg ctgacaagat ttgtgttcgg atatcatcca
    21421 caccatttgg agtatttggt aaaaagatag tttgatttcc tttagaggca aaggtattca
    21481 aggtatccaa atactggttg gtcaagagga tagacatgat ttgttcttct gtcatgccaa
    21541 cattggcttc cttgagttcg gtgatagact ctgccaatcc atccacaatc gccttacgtt
    21601 gttgggcaat ccccacacca tgaaggcggt ctttttctgc ttctgcttca gctgcagtga
    21661 caattttaat cttgtcagct tccgccaatt cttgtgctgc gacccgctta cgttgcgccg
    21721 cattgatttc attcatggat tgcttaactt ctgcatctgg ttcgaccttg gtaatcaagg
    21781 ttttcacgat aatgtagccg taagtggtca tttcttctgc tacttggtgt tgaacctcaa
    21841 gggcaatctc atcttttttc tcaaacaatt catccaaggt taattttgga acagaagagc
    21901 gaagagcatc ttcgatataa gatttaatct gagattctgg acgtatgagt ttatagtaag
    21961 catctgtcac gctctgctcg ttgacacggt actgagtcgc tacattcatc ataacgaaca
    22021 cattgtcctt ggtcttagtc tcaaccacaa tatcactttg caacaagcgc aactgaatcc
    22081 gtgctgcaat cgagtcaatc ccaaaaggca agcgaatatg aataccgcta ttagcaacct
    22141 tttggtattt cccaaagcgt tcaataatcg ccaccgactg ctgacgaacc acataaactg
    22201 tactcagtgt gactatcacc aataggagca cacaaacaat cagaaaaatc atgaaaaata
    22261 ttgccataat ggaacctcca caagtatttt tctagtatta tagcacattt aaagaaggct
    22321 gtgccgtttt tactgcgatt tttcctgaaa tgtcaataat tagaggtgaa ttgtcctatt
    22381 gtcgtccaat ctcttgctaa aataactctt tataaaaggc aatcgtttct tctaaggttg
    22441 gcataaatgg atttcctggt gcgcaggcat caatcaaggc attcttagaa aggtattcaa
    22501 agtcgaaatc tttttcttca ataccaagtt cagtcagttt cttaggaata cctactgtct
    22561 cagaaagctt ctcaatctca acaatcgcat aatcggcaca ttcttgatct gatttacctt
    22621 ctacatgaag tcccaaggct ttggcaacat tgcggaaagc ttctggtaca cgtttagcat
    22681 tttcacgttc tataactggt agcaacatgg cacagcaaac accatgtggc aaattatata
    22741 ctgcaccgag ttggtgagcc attgagtgaa cataaccaag accagcatta ttaaagctca
    22801 taccaccaag gaagatggca ttgaccatac cttcacgcgc ttcaatatca tgtccatttt
    22861 ctacagcacg aggaagatat tccttgataa gctcaatagc accaatagac agtttcttgg
    22921 ttacatcata agcaccaggt gttaccaaag cttcaacagc gtgagtcaga gcatccatac
    22981 cagtagcagc agtcaggcct ttaggtttgg aaagcatgag ttccgggtca ttaacagaga
    23041 taagagcaag gctattcttg tcaaccatta ccatcttaac cttgcgttct tcatcagtaa
    23101 tcacatagtt aatggtaatt tctgctgatg tacctgccgt tgtattgata gccacaactg
    23161 gcaagccttt tttagcagac ttatgaagcc cttcataatc ctgtggtttt ccaccatttg
    23221 tagccatgat agaaatacaa ctagctgcat cctgtggaga acccccacca agactgatga
    23281 taaaatcaca gccatgttct tgcaaagcag ctaccccatc tgtgacattc ttacaagtag
    23341 ggtttggctc tacatcgcta aagatgacat attcgattcc ttctgtatcc agtggtttta
    23401 aagtcttagg taaaatatca ctgccttcga tgtacttatc tgtaaccaaa agtgcctttt
    23461 tatagccaag ttccttgata taaggaccca cttcatttac aacacctttt ccaataaggt
    23521 tgactgccgg aacataaaat gtagccatat aattttcctc ctgcgcctcc gcgctatcta
    23581 tttaacatca ttatattact ttttgtattc gtttttaatt atttgtgaat tgtttaacaa
    23641 atctttttaa aaggatagga gggacgtaag ttcacctcct atataaacaa gttttattta
    23701 tgtagtggtc ccaacaactg acatgcacga tagtctgctg attctagatc ttctgttcca
    23761 aataaggacc aatttttagg tctaaagata tcttcctcag gtacattatg catattgaca
    23821 ggaattctca acatagaagc caaggtaatc aagtctgctc caatgtgtcc atatgttatg
    23881 gctccgtgat tagctcccca attattcatg acgtcataga cagacttgaa agcacctttt
    23941 cctgtcaaac gtggagcaaa ccaagtagtt ggccatcctg gatctgtacg attatctaaa
    24001 gtatggtgaa catcttcagg aagttcaagt gtataacctt ctgcaatttg tagcactgga
    24061 ccaacccctt ttagaagatt gagacgtacc attgttactg gcatatcccc cttcgtcaag
    24121 aaacgagttg agaatcctcc tccacggaag tattcgcggt ttgctggtgg gaagtctgta
    24181 ttttcaagca tagcctgcac ttcactttca tccaactccc agaatggttt cataacaggt
    24241 ttgccatctc gagtagcttg ccctgtacca tccaatgtac aagaaccaga gttgattaga
    24301 tgtaagaagc cagctgcagc acgaccctct aaagtatgtc ccgttacacg tttaacagcc
    24361 tctggactcc aataagtgcg cacatcagca aagatttgtg gagtatttgt taatagataa
    24421 ttaaagagca tagacacacc atttagtgaa tcattctctg tcgcaaatac aaatggtttt
    24481 cgaataccat tccagtcaaa ctgagtattg aggaaagttt ccataaagtc cccatttggg
    24541 aaatggtctg tccactggcg ttgaccttgg aaaccagcta ctaaagcatg gtgaccaact
    24601 gcttcttcct caaaaccaag ttcagcaagt cttgggttac caaccattaa gtcacgtcca
    24661 atcatgaaca tcttaataac aaattcccat tgtttttctt tctcttcttt agaaagaatc
    24721 aaatcctcac gatttcggtc aactccttct ttgatatgtt cttttaccca aaccatagca
    24781 cgttcaaact cttctgggtc gtaaatacca cggtccatac ggcgcgtgaa ctccgtcata
    24841 tctaccgatt catttcgcat tcctaagtat tcttggaaga aatctggatt tacaatagaa
    24901 ccgccaatcc ccatcgaaac actacccatt gataggtaag cagtgtctct catcaagcca
    24961 gttgcaagag ctgcacgcgc ataacgtaaa agtttttctt tgacatcttc tggaatagct
    25021 gtatcattag cttcctgaac atctctacca taaatcccaa aggctggaat ccctttttga
    25081 gcatgtgaag ctagtacagc tgcaagatag acagctcctg gacgttctgt cccattaaat
    25141 ccccaaatag catgaggaat atctggagac atatccatag tttcactacc ataacaccag
    25201 catggtgtaa ctgtaattgt tgcgcaaaca tttgattttt taaacaactc atgggaagct
    25261 gcagcctctg gaacacgacc aatagtagat ggagaaatca cgcattccac aggttcccca
    25321 tctggatatt tcaatgtgct tgaaatcaaa tctgccacac ttttagccat gttcattgtt
    25381 tgcacttcaa gtgattcgcg tacaccttga cgacgaccat caatagtcgg acgaatacca
    25441 atacgtggat gttgaatcat actattttcc tcttattttt ctgtttcttt catactacca
    25501 tcgccattat atttacggta gcctgggtga cgacctgtaa ccttataatt ttctcgcatt
    25561 gagaatagac gttctaaagt cggacgagca atttcttgct cctcaatgcc ctttgtagaa
    25621 agtaacattc ttccgtggaa ggttgtcttt gcgactaatt ctaaagtttc catacggtag
    25681 tatgctgtaa ttacatcgct tccgacagtc agagctccat gattttctaa tagcatgaca
    25741 tcatgatcgg gcagataagg tgtaattgct tctggcactt ccattgtaga cggaactcca
    25801 aatggcgtta taggaattgc ccctaccaca atcgcgctct caattagtga ataagtatct
    25861 aaaggaatgt gtgcaagagc aaatcctgtt gcaatcggtg gatgcgcgtg aacaactgaa
    25921 cggacatcct cacgttcttc gtagcaccga atgtgcattt taatttcact agaaggacag
    25981 taatcacctt ctgcttctaa aatctctcct ttaagattta acttcaccag cttttctggt
    26041 gtaataaaac ttttgctgat accagtaggt gttgcaagaa tggtatcctc atctaatcga
    26101 acagatacat tcccatcgtt agcagcaacc caaccaagtt gccacatctt atgacaaaca
    26161 tcacaaatct gttcacgaat taatttttca tcttgagaca taaactcact cctttctaaa
    26221 aatgaagttc gaattcaaga tttccgttac tgttaatggt aatagtaacc atatgatttt
    26281 tctgatcaaa attgagagat ggctgatcat aggaattatt tgttcctgat aatgaatgaa
    26341 tagtaggaag tttatctata cctcttaata ctatctttgt aacccttttc tctccaaact
    26401 gagtatcttt gatataatgt tcttcaatcc acttaatcgc acctttcttg gtcaattgtg
    26461 gtagtttctt tgcctgattt gcatcttgag cattagacca tagtgaatct ttatttgttc
    26521 taaaattatt taaattcact ttcaatccat tacttattct ctcaaaaata ccataggtat
    26581 gaggttcaaa ttcaacatcc atttctaaag aattaaattt taatttccca gtctgtttaa
    26641 cattctcatt taccttgtaa ttatagacaa accatctatt atctaatttc tgagcaaaga
    26701 tatctccttc ataattcata ggatacagct tatttaagta ttcttttcta gcctgagtag
    26761 agctaaattc tggagaagtg atttccttaa tctgaatacg gctaccagaa acagactctt
    26821 tcaatttatc tgtttttaaa acacctggaa tagctggaat aacattataa cgaccagtca
    26881 tgtataatgg agtttgttct ctatcagtat ttacgtttac aaagaactta ccatttcctt
    26941 tatttgaata gtctccatgt atgaatactt ttgtatcctc aagtaccttt tctttggatg
    27001 gtgctggatg cgctattaca tatctaaaaa attcttttat tacttcgcta aagagtaagc
    27061 tttctttatt atttacacca taggtataag ctgggtgttc aaaattataa actacacctc
    27121 cattaaggta aacccctaaa gcttcttctc ctagcataga ctctggttca gtcaaccatt
    27181 gtctatctcc ttgacttttt ccgatattac cacttgcaaa cagtttccat ttacctgtct
    27241 cataccactt ccaagtatcc atcaaaccac cccattgata agtatgattt gaaagccaaa
    27301 gtcccttcat ataactttct gtagttgaat catttccctc agcagcaggt gtatttttga
    27361 acatgaaaat aaggttcttc cagtacttat caacagattt ctgaaatgct atcttaccgt
    27421 tttttccaaa tgctttttct attgcagaac cattattttg ttcagcccat ataaaatatc
    27481 ctccattttt agctgatact tttaagtaat ctgccgcctt attttcaata tcatttgccc
    27541 aaatccaata attctctgta ctgaaaatac catgcaaatt tggatatttt tgatacattt
    27601 tatcaatcca gctggtactt aaccaatgtg ccgaagtata ataaggcata ttaccagcag
    27661 tgtaaaccgt cagaataact ggaattggtt cattttttcc agtcttagga tttacatatt
    27721 tcgctgcttc ttctaacata tgttcataaa aatctctagc agctccatct cttttagtaa
    27781 gatcatctgg atgtaactgt ataacagtat atggttttaa gtcatctggt atattctccc
    27841 acttacctgt taatgtatct cctccccaaa aagtatattt cccttggtta aactcttctc
    27901 cgttagcata taaaggcatc ataagtaacg gatgttcatt attaatttca cgacgtttat
    27961 caacttctga ccaatcatta ggattcttaa atttaccatt tgccataaac aaggctccac
    28021 ctaaaaccaa ttcgtcagcc catgtatgtt tccctgaata tgatttaagt tctattgtct
    28081 gtgtatcttt gggaatttca acatcaacca gaaatgccga tgtatcatac ttaattcctt
    28141 ttggatattt tgaatctgat gagtaaatga ctttaccatc cgcaacaact tcaaattttt
    28201 gaatatctgc gtaatctgaa tttaaatgat tggcgctcct atcaattccg acataggaaa
    28261 taaatcttgt aacattagca cccgaaacat catattttat actagacggg ttgcttgcta
    28321 cagttcccaa tcccttatta aattcgactt ccttaccgtc aattagtaat tttattttat
    28381 tattagaccc gttattacca ggtgtaaacg gtttatcttt ctgaactgtt tttgatttat
    28441 cgtcatcacc atgagtagca tcaacccatt ctaaatcaga aagatatact cctccattaa
    28501 ttcctttatt aagaagatct ggagttatag tttgagtact aacagtttta ataagtttag
    28561 catcagcaaa tacaacctca tcaccccatg tatgttctcc tgcgaatgat tttaaggata
    28621 tttttttagc gttttgtgga attgtcacac taataaattg tgcctgggta ttatatctga
    28681 atccttctgg attagttaca ctactagaat agacaacctt tccatcaatt tctatttcta
    28741 ttctatccac tactgcatgg tctgatctag aactattagc actttgatca attcctatat
    28801 aagtttcaaa tttttcaaac ccttgaccgc tgatatcata gctgattact gatggagaat
    28861 ctgcgactgt tcctattcct ttatcaaaat atttaacttt atcatcagaa gtgagcaatg
    28921 aaatcttagt atgctctcct ttatttcctg ttgtaaatgg agcatctttt tgtactgttt
    28981 ttgttttatc tatatcacca tgagttgcag aagaccaatc catatctgaa agatatgtca
    29041 tctctttatc aatttcttta tctttagtaa taagtttttc taagttattc cctgttactc
    29101 tagcagtttc agtactagct ctgttattag aattactttg aactacatct gcataaacca
    29161 aattacttcc taaaaaactt gttaaaacag ccgtagctat taaaatctgt tttgctattt
    29221 ttttactttc catttttatt tcctcaatat ttacatacaa cttcttcaat aacaaataat
    29281 tttgtaagat attctggaac acaaagtgct aaattactta aactgacttt tattccagca
    29341 ttcattaatt catctccata aaagaactca tcaaatctag agacggaata gcatttatct
    29401 ttatctaaac cactaaaata aactcttgta taacctggat tcaacttact attcaattga
    29461 gcatacaata aaatcgattg gcatttatct tttgaaacaa cttgccaact agcagaatca
    29521 caactaaaag gactgtttat cctatagaaa tccccatatt gaaacaatga acgatatttt
    29581 ttataaaact gaatttgttc tctcacttgt tctttttctt ctaccgacaa tctcgtaaca
    29641 tctaattcat aaccgaaaga actaaaataa gctacatttg tcctagtgtc caaactcgtt
    29701 tgtcttccac tttgttcatt tggagaaata gaaacatggg ctgtcatcat tgatggagaa
    29761 tatccataag aagttccatg ctgaattttc aatctttcta tcgggtccgt atcatcactc
    29821 gtccacgctt gcggtgcata atacataagt cctaaatcaa aacgtccacc acctgaagaa
    29881 caagattcaa atagaactga agggaactta gttattaaac gatctaataa ctgataaaga
    29941 cctaagatat atcgatgacc aaattccatc tgctgttcag aatcaagttc aatactataa
    30001 atatctgtta tatgacgatt catatcccat ttgatataat ccagatttgt tttgattatg
    30061 attttagaaa tagaatcaaa aaggtaatca acaacttcct gtctcgtcaa atccaacaca
    30121 tattgatttc ttcctactga cttctctctg tctaacaaat ggatagtcca atcggcatga
    30181 ttcttgtaca aatcactatc aatagaaatc atttcaggct caaaccacaa accaaattgt
    30241 aaacctattt tgtgaatttc atctgcaaga aatccaatac cttcaggaag gcgacttcta
    30301 tctgttaccc aatcacccag agaacttttg tcatctttcc tatgaccaaa ccaaccatca
    30361 tccagtacaa ataattctat ccctaaatct ttagcagcct ttgctaaatc taaaattttt
    30421 tctgtactca agtcaaaata aaatgtttcc caactattga gtattatagg acgactagct
    30481 tgagaaaaat taggattaac taaatgatgt cgataaaaat ctgatagttg ttggctcatc
    30541 tgattcatcc cttgatcaga atagatcaca attgcttctg gtgtcacaaa actttcggca
    30601 ggatttaata aaaaacgaaa ttctactgga tttattccta ccgttactct agcggtgtca
    30661 aaatggtcaa cttcaatcat attttgaaaa tttccagaat agataaagtt aaaaccataa
    30721 acctcaccac tatgctctgt agtttccctc cttgatagca taaagaaagg attttgctga
    30781 ggacttgatg agtatctcaa gctatctatt gcttgaatac ctggtctaag cgaagttcta
    30841 tataactgac gttccctcag ccatgctcca gaaaattgaa taaagtcata ttgactatca
    30901 ggtagatcta gctgtaagct cattgctttc aaaagagtca acttattatt gctattattt
    30961 aaaaattccg tatttctaac taagacattg tattccggaa aaattgtgta atttagtcta
    31021 acagttaaat ctaatatgga atctgttaaa ataatcgtta atgtttccac acactgacca
    31081 atatcatcaa atgttgaagg tagagagtta agacgatttt tccctttttc aagttcaaaa
    31141 ccttgatatt ttagtgtcgt tatcctacta ccattcattc cttgaacttg aaaggctgga
    31201 tgccgaaaat ctcctttccc atatgaagaa tattcatttt gtatcataga ctgttgaata
    31261 tcctcaaatt cttcagaaaa agatacttca aatcctcttt tttcataagc catcaattgg
    31321 ttataatttt ccttgacatg aatccttttc ccaaaatgta gatgttgaag ttccccattt
    31381 tctaaaattc taaaaatata actactatct ttcattgcca aatgaaaaac ggtctcgtcc
    31441 ttattaatat aaatcgtcat ctctacctca caattttttc tttacttctt cagtatcacg
    31501 atagagtacg gtgccaattc tatctcatct tcttgaatag taaaatctcc aattactctg
    31561 gtaaaattct ctatcgaaag attctctatt tttatttttt gtttaatctg agcaggattt
    31621 ctcagagaga gaatttcagt agaagtcttc tgattgtgac acttataacc ataaatttca
    31681 aatttttcag gacttcctcc tattttttta ctatatttta gtgtttgata attctcctct
    31741 atccatttga cggcacgagc attggctttc cagcgttctt catcaaacat atcaaaagaa
    31801 tagtgaaact cccaaaaagc attccctctt gttgaaataa ataatagata agcttcaaaa
    31861 tctggtattg atgcaaacat ttgatgatcc atgtaccagg tatttgcact gacagcatag
    31921 attggttcat gattataaat cgaccacata ggtaactgta tctcacgttt ttccaaaaat
    31981 tcttgatact gaatatctcg gtaagtaatc atacgattga tatcattacc tgcattctct
    32041 gtaaagccta catcttgaga tatttgaatc cataaactat tgacccactg taaaaaccat
    32101 ggactaggat ttacataaga agtcaagttt aaccaacaat cttttcctcc tctctccttt
    32161 cttagatcta tcaacagttg aattaagaac tcataaaccg ctgtcatggt atacataccg
    32221 tgcggtccac tcttatcagg tttgtcaggt tgaagtaacc aaccatcaat tttccaatag
    32281 ctgatatcga attctttttg atattccaac atctttttct tcatttgatt gagatagtta
    32341 aaatcagcca cgtttacatc atttgaaatc aaatttttag atccaatatt taactctgga
    32401 tgtgcttcta accaatcact cataatgatt tctgtcccat tgtaaccacc tcggggacca
    32461 atccacaatc ctaggcttga accaaatcca tttacaagat atttaatatt tctcaaacca
    32521 tttgggaatt tatgattgaa ttcccaaact gattgatagt ttgtccaacc atcatcaaca
    32581 acataagcat ctaaatgaac tccatgattt tcaaatccat ctcgaatctc agaaaaactt
    32641 tttaaaatac cttcctctgt aatatcggtc atatggtcat accaggaatt atactgttta
    32701 cggaaataac taggttgagc tattccttca acatattcaa aaaatgcctc ttgaatctct
    32761 tcttttttat aagaacatgc tcccccaata atacaagacc acaaactctt ttcttgattt
    32821 acaacagttc ccaagtaata tcttgataca tagtgtctac catctacctt gttttcagac
    32881 attggaaatt ccattcctaa gaataaagaa ttcgcataaa caggttgtcc caattctaca
    32941 taataaccgg aaaaattcgc catttcctta atacaatctt gtcttttcgg atagaaaata
    33001 ttgtcttctg tttcaaactc aaaactctct acctctacag atttaataac ctcagtagat
    33061 gattctaaaa ctaattgctt cgaaagaaca tcatccctcg attcaaagat taaacgtaaa
    33121 cgaatggaag gacaaacaaa agaaacctga attcgcgtat ctccctcttc cctaacgatt
    33181 gctgaaaaat gatttgaaga aagtcttata ccattctcca atgtaatggt aaattcttct
    33241 ttcgaaacat ttttatcatt actcctgccc gtttgtttac gatatcagta gtataaaatc
    33301 gaccatctcc ccaaaagaaa ttacgtctta catttttatt ttcaattttc atataaacta
    33361 ctctctcaac tcaattttga ttacgctatc aatcaagtct ggtaatggat aggtaaaatg
    33421 tggaacttct ccaaactgtg caaaacaaat tcctttgtag gcattggtcg tccagctttc
    33481 tgaaattttc acctcacttc catcatgaag aaagctcatt ctttttacgt tttctttact
    33541 aataccaaga agagctaaag gacctatagg ttgttcaaat acatgagcat aaaccgtatt
    33601 tccattacga gtatagtatc cccaatctgg ttttggtaaa ttttcatctc cactacatcc
    33661 ataaattgcc tcaccatttc gagacatcca tcgatgaaaa ttatctaata ttttcttact
    33721 tgaatcatta attcttccca aagcatctgg gcctacatta agaatcatat ttccgttttt
    33781 actaacacat tccactaact ttcttatcaa agtttgacta gacttatata gataatctgt
    33841 aggattataa gcccaattgt tattcatagt tagacaaagt tcccaaggaa caggttcacc
    33901 tttaaagttt cgaatacctt cgtgaggaac aatttgctct ggactaacaa aatctccagc
    33961 gtaagaggta atttcatctg taacgatact tccgaatcct tcacctgatg tttctaatct
    34021 attatctacg ataacgtttg gctgataatg acgaaccatg tctattaatt ttgaagctcc
    34081 ccatttttca cccaccatgt cttcataaga ataatcaaac cataatatgt caatctgacc
    34141 ataaccagtt acaatttctt taacttgatt gtgcaaatac tccaaataac ggtcaaagtt
    34201 aattttctca tctcgatagg cttcatttcc tctcattgga tgatttagat cagcatattt
    34261 agggaaatca ggatggtgcc agtcaatcaa actaaaatat aagcctactt ttaaaccttc
    34321 agctcgaaca gcatctacaa attctttaac taaatctcta cctgcaggtg tatttgttgc
    34381 tttataatct gtaaattttg aatcaaacaa acaaaaccca tcatgatgtt tagccgttaa
    34441 aaccatatac ttcatccctg cagcttttgc ttgtttagcc cattctctag ggttatattc
    34501 cttaggatca aaagctcgaa aatatggttc ataatcttca atagataatt tctgatgact
    34561 acgaatccat tccccttttc ctggaataga atataacccc caatgaatga acatcccaaa
    34621 tcttgcttct ctaaaccact gagttctact attgatagtt tcaagtgtat gtttcatcct
    34681 tttactgctc ctcctcctaa agcttcaatg aagtatttac ttgtaaatgc gaatagaatg
    34741 attggtggta atacgattac aacaatagct gaaaatagac cattataatt agtattaaaa
    34801 cttgtagtaa attgacctag taatgctggt actgttaatt catttttatc aatcaccaac
    34861 atagatgccc aataatattc attccagtta ttaataaagg caagtactgc tgctgttaaa
    34921 attcctggtc tagcaattgg caacatcact ttccaaaaag tttgagcata tgtcgcacca
    34981 tcaatctctg ctgcctcctc caattctttt ggaataattt caaaatagtt ctttataata
    35041 aagaaactca tagcaattcc actacaagag tagaccagaa ttagagcaac tggggtatta
    35101 taaatcccca actcatttac taatctataa actggaaaag tcatagctgt tgctggaata
    35161 aatagagtag aatacagcat agaagtcacc aacttcttcc ctctaaattc catcctagca
    35221 ataacatatg aagacatgga gatcataaca atgctaataa taactgatat agacactact
    35281 ttaaagctat tccaaaagta agtaaaaaca tgaagttttg taaaaacatt tatataacct
    35341 tcaagagtaa agtcaatcgg taaactaata cctggatttt tcataggatc tgcttttaat
    35401 gatgataaaa aaatccacgc aatagggaaa atagaaatta aaatggtaag gagcatataa
    35461 ccatatataa gaactttgcc ttttttacta ataccattta tatgtgtatt cataatcatt
    35521 tcccaccttt cagtcttttt ctttctctga ataaaatatt aatacaaacg ataatcaaca
    35581 ttccacctaa gatttgtata actccaattg tatttgcacg agcatattga gttcgtgagc
    35641 tagccactgc taattctcga ataacaaaac tgatactttt tgttcctgca gcaccatttg
    35701 tcaaaaagaa tacttcgtta tagagcaaaa atcctgaagt tgctgccata attgaaacag
    35761 ttttaattgt ccccttaatc atcggaatcg taatatacca ctctttcctc caaccagtaa
    35821 tattgtctaa aatagcagct tcttgaactt cttctggaat agcaaaaatt tgcccaagaa
    35881 tcataatggt tgatgctcct gcaaagaaga tataagcgcc agtcatagct actatattta
    35941 atcctggagt caacagtact gaatctttaa acgatggatt aaatagatga ataatttggt
    36001 taacaacacc atagtttgga ttatagattt gaagaaaaat caagcccata gcagcactag
    36061 aaatgatact tggtacaata taaagattcc tagatatctt ccagcctttt aatttcttag
    36121 ataatgtaat tgcaacagat acagctaaag gaacttgaat aataacacca attacagccc
    36181 aacgaacaga attaattaga gcttctgtaa aaaatgggta ttctttaaaa acatacctat
    36241 aattttcaaa taatttatca aatccaagaa actcaggggt gtttaaattt gtataatccc
    36301 atttagcaaa tgaagttaaa aagattgtta ctacagaata aaaataaaat agaaagaaac
    36361 aaatcaacgt tggcaaaaga aataaaaaga taaatcgtct tttttgattc ttcctatttt
    36421 gtaggctcat aattttttgt gccataaaca aactcctttt ttcaactata taagtaaaat
    36481 caaggtctta tcaaaagaaa gcacggatac gtgaccctgt cctctatgaa cacaattgaa
    36541 ctttctcatc aaatacggga aggagaaagt actaggcaaa aaagactaat cgctagtctc
    36601 gctaaagact ttattcggtc tggtatgtgt atctatctgg attccagtac tactgtctac
    36661 gaactctgtc cctatctttc tgaacttgat aatttgatta tttttacaaa tggtttacat
    36721 actgcacaaa ccctatctga aactgttaaa gatagctcca aaatctttat cacatctggc
    36781 gaggtcaaac atcaatcctg ttccgtggtc aactatgata aggaaaattc tttattagat
    36841 cattttaata tcgatttagc attttgttca gcaagaggta ttgatgacca atatgtttat
    36901 gaagcttctc tcagccaagc tatttcaaaa aagaatatta ttgacaaagc ccatgaaacc
    36961 atcttactga ttgatagttc taaattttac aagactggat tttttaaaat taatcccctc
    37021 tccaaataca caacctttat ttctgacacc gtgccagacc aaaaattatt agacgcagtc
    37081 gaattatttg atggagaatg ggtttctgat attcaatgaa aatcaaatag gaagctagtc
    37141 tcagcttgct cacagtacag atttgaaaac tgatcaagtc aagtccccca tggacacggc
    37201 aagacgaagc tgacatgatg tgaagagatt ttcgaagagt attcgttctg tctgctgact
    37261 gatttacaaa tattcaccac atgacattat tttcttagca attctaaaaa cagaggctgg
    37321 acaaaaactc aatttcagga gaaaatggag taaaccttcc cacaataaaa cgcatagtat
    37381 caagtttttg cacacctgat attatgcgtt tttctgattt taaagacttt gtcgcctaga
    37441 ccctatattt caagaattaa gtgaccttga tgatctaaat atattgtggt atactatttt
    37501 tgtcatcggt taccgattac gttcctatgg gtttgtgaga ggaggtgaaa ctaatgagcc
    37561 ttatcataga gctcgctctt actattatag cggatgttat agctggaatt atcttgtatt
    37621 tcgtctgcag atggctagat agtaaggagt agaccgactg actagcctat aaacacccgt
    37681 taaatcgcta agatacgtca aaaaagccct taactacggc catagttagg ggctttggtg
    37741 ttctaatgaa ccttatcaat taactacatt ttagcatata atctacaata gttcaagcat
    37801 taagtgaggt taatgatcta aatttagtgt gatataatac ttttgtcatc ggttaccgat
    37861 tacgttccta tgggttcgtg agaggaggtg aaactaatga gccttatacc agagcttgct
    37921 cttactatta tagcagatgt tatagctgga attatcttgt atttcgtctg caaatggcta
    37981 gatggtaaga agtagaccga atgactagcc tataaacacc cgttaaatcg ctaagatacg
    38041 tcaaaaaagc ccttaactat ggcactagtt aggggctttg gtgttctaac gaaccttata
    38101 cactaactac attctagcat ataagcccag atatttcaag agttttattt attttttcag
    38161 gttcccttag ttctgaaagg tctataatga agttagccat ctagtatcaa aaaaccgact
    38221 agctcttatg aactagtcga tttctcatca atgcgccaac atttcttggg cgatttcttg
    38281 gccagatagg ttatctgggt agtaggttgg ccagttgtcc atttcttcaa agagggcttc
    38341 ttggcttgtg cctccaaaga agatatggaa atgttctgcc ttaactgggg caacattgtg
    38401 gtcactaaac tgaacatact tgaattgtcc agcgtcagca tctgtggctt caaagaggaa
    38461 acgcacgcca cgattgcctt tcttgtaagt caaaattttc ttaccgacat acttgtaagt
    38521 gtatttcttg ctttgtccac cttgaacaaa ttccatagta ttatcagtaa tgttaatctt
    38581 agtcacatct gtctgatagc cttttgtata gtaagccttg tactcagcct gggtcatctt
    38641 accagttaac ttagccttgt agtcaaagac ttggtcaaac gtgccgtctt caaggaaagg
    38701 ataaactgat tgccagttac ctgcatagtc actcaaggta cggtccttga cagctgcatc
    38761 ctcgaagtaa ccattttgga ctgtcttggt atcctctgcc ttttcaggtt cgattgctgg
    38821 gccttcttgg tctgttgttt gtttcaaagc cttgaggttt ttctccatca cggaaatgta
    38881 gttttctcca gccttggtgt cctcttctgt cagactttct aaaggattga ggacatcagt
    38941 tttgacacct gcttcttttg aaagtgtgtt agcaagggct tgtgaggcat tttcttcaaa
    39001 atagatatag gcgattttat ttttcttgac atactctgtc aattctgcca agcgagcagc
    39061 tgatggctct gcatctggag aaagtcctga gattgcgact tgtttgagtc catagtccaa
    39121 ggcaagatag ttaaaggctg cgtgttgagt cacaaagctc ttttgttttg cttgagacaa
    39181 gccttctgcg taagccttat ccaaggcttg caatttttcg atataggcag ctgcattctt
    39241 ctcaaaggtc tcttttttat caggataatc tgctgacaag ctgtcgcgga tgtgctctac
    39301 tagtttaatg gcacgaactg gtgataacca aacatggggg tcaaactcat ggtgatgacc
    39361 ttcttctcca tggtcatgat ctccctcttc ttcctcgcca cctggcaaga gcaacatatc
    39421 gcctgtcgcc ttgatggttt tcactttttt cttatccaag gtatctagca atttaggtac
    39481 ccatgtttcc atgttttcat tttcataaac aaaggtatct gcatcttgga ttttggcaac
    39541 tgccttggca gatggttcgt attcatgagg ttctgtccca gcaccgatta ggagttctac
    39601 attagccgta tctcctgcga cttgcttggt aaattcatag acagggtaaa aggttgtcac
    39661 gatattgagt ttaccatctg cctgtttttg attggaacaa gccactaaaa acaaggcaca
    39721 tagactggct agtaataagc taattttttt cacgttcgtc tcctatttga taaaacgtct
    39781 tactaaactg attagtataa agacagttac aaaaataatg gtaatacttg cacttgcagg
    39841 tgtttctgca tagtaggaaa tgtaaagtcc tgctaccatt cccaaaaagc caatcgcact
    39901 ggcaagcagc ataaccgatt taaagttttt ccccagacgc agggcaatac tagctggcaa
    39961 gaccataatg gtcgatacca gaagagctcc tgctgcagga atcataaggg caatagccac
    40021 ccctgtcacc atgttaaaaa gaatggacat ggtacgaact ggcaagccat ccacaaaggc
    40081 cgtatcttcg tcaaaagtta agatatacat aggacgaaga aagagaaagg tcaaaatcaa
    40141 aacaaccgcc gcaatgacaa agagggaaat gacctgttct tcactgatag tcacgatcga
    40201 accaaagaga tattggtcca aactcattga actcgagctt ttacccttgc tcatgacaat
    40261 cagagaaaca gccagacctg ttgacatgag gatagctgtc ccgatttcca taaagctctt
    40321 gtaaaccgta cggagatact ccagaaagac cgccgcaatc aagacaatgg caatagtaga
    40381 aacagttgga gaaatcccca aaaccagacc aaaggctaca cctgaaagtg agacgtggct
    40441 aagggtatca ctcatcaaac tctgacgacg caagatgagg aaggttccca ataccggtga
    40501 gaaaagactc atagcaataa ccgccaaaaa ggcgcgctgt ataaagtcgt aagataataa
    40561 actaagcatg gcccacctcc tggccattct catgaacgtt gaaacaacgc catggcgagt
    40621 cttggttacg gactagatga atattgcgat ccgcataatc cttaacttct tcagggtcat
    40681 gggtaatcat caaaacagcc ttgccatgat gatgggcgct gtggtgcatg agttcgtaaa
    40741 attcattttt acttcctgca tccatccccg ttgttggctc gtctaggata aacacatcag
    40801 ggtcagaagc aaacatacgc gcaatcaccg ctcgctgctt ttgtccccca gatagagacc
    40861 ccaagcgttt gtctcgatgt tcccacatgc caactgagtc cagactggcc ttgatatgct
    40921 cctcatcatg agcattcaaa cgacggaacc agccttttct cggatagcga cccgacttga
    40981 caaattcata gaccgtactt ggaaaaccag cattaaaact ggcaatttgt tgaggaagat
    41041 aggctattct caatttctta ccttgcgtat ttgtctttga aatagccacc tttccaatgc
    41101 gtggttgcag aattccaaga ctagccttga tgagcgtcgt cttagccgct ccattttccc
    41161 cagtcaaggt aacaaattcc ccactatcaa cactataatt gatatgttca agaacaggct
    41221 ccttatcata atagaaggac aaatcctcta ccgtaatata tctcattatt tgatttctcc
    41281 tactaaagca gtcaaaaacc gctgaatcac tttttgttca tttggagtaa actgagtcgc
    41341 cacttgttca taggttaaaa gtgtatgctc atggtgatgg tggtgctcct cagcgattgg
    41401 acgagccaag tcagtcaact gataaaaaat cacacgcgca tctttagaat ctttagatgt
    41461 ttccaacatc ccttccttga ccaaagactt aatggccttg gtaactgccg cctgactgac
    41521 attgagacga cgggccaatt ctgaatttgt taaagattcc tctgacaaga gcataaggat
    41581 atgctcctga gtattggtca gggccacctc gctagtgcaa tgacctatta ggatttcatg
    41641 ctgattttcc gcctgcaaaa tcacctcatt caaaaaagca ttgatatcct ttgctagctg
    41701 tctcatatct gactcctttc cttttagact tctctttttt aagagaaaaa tactattctt
    41761 tgacattttg tttaccagtt aattatatca caagcaaaaa aagagtcaag aaaaaacgtg
    41821 aaaactagtt tcattcttga actcttctat attatattat ctattgaaat tctttgacat
    41881 ctccatcata agtcgcccaa tctttgctga aaaagcgctt attcagatgg taagtcggag
    41941 ctggtgtggg attggatagg aaaggatcaa ctgccttgtc aaaagccaac caacccaacc
    42001 agccaaggtg aatggtgtcc ttcataaaga aaggctcccc gccgtcctta gaaaaatctg
    42061 ctatattggt aaaaccttga ctttctaact ggtagcgaat cttctgcacc gtttgttggt
    42121 acatatcctc tcgtagacca gcatagtcca tccatttttt attaacaggt ggaatgataa
    42181 aaatcgggtt taccttagat ttagaaaact gtgttaaaac caactgcaag tcattatact
    42241 ctggcgactt gagataggta aagcttttct gagaatcctt taatttcttc aaatccttct
    42301 tgatctgctc attatagaaa taattttcca ttcccatctc attattggaa gtattttttt
    42361 cagcatctgc tttgacaaca tcttctattg cttgataaga aaactggtct ggcaagattt
    42421 ttaaatactt agctacatgc ttatcgtagt taacatagcc tctaaccgaa aactgaccaa
    42481 aaaaggaggc ttggcgttca ttaaaacgag ccaataattc aatcatttca ttgtctgctg
    42541 tcgacaattc ttctttactt gccaacttct gaaccaggtc cttcatagct acgtttggga
    42601 actgttgcag taagcgagtc gctgcatatt gactagcctg atccccagat tgatgtttca
    42661 gaaaactagt caactggtct ccattaaaat actgctggaa ggctgctgga tcatagccat
    42721 ttttactgaa ccactgaggt gagataacat acacaacttg tttattctcc agctgtggta
    42781 acatctgttg cattccaaaa tattggttaa gcgatgcagc tcccccctgt cctaaaagat
    42841 aaggacggta ggaacgattg tatttctcag ctaataccgc aggatgagca ccgtcaaaac
    42901 gaagccattc actagagcca aagaagggaa caaaacgcac atttggatca gatagtgctc
    42961 tgactttttg acttcgctcc ttaaaactat cgatagtagt agccactgct gaacgctttt
    43021 cagctcctag attatgatgc atctcagtag gataaaagaa aatgagcaga aaaaccaaca
    43081 aaccagcgat caagaccggt ccgaagatca tccataagcg tttaagcatt ttgtagctcc
    43141 acaataccag ctatgatttt attagctgta ttccagtcgt cacgaccaaa ctctgttaca
    43201 gggacacgaa tgtcaaaacg gttctcaatc tccacaatca actcaaccgt tcccatacta
    43261 tccaagacac ctgcatcaaa aagatcttca tccatcatgt cagaaacatc ttccataaac
    43321 aactcatcaa taatttcaat aacttctgat ttgatatcca tattttattt ccttttattt
    43381 tttaaaccat agattattca agaatccaga aaagattaag aatgacaaca tgacaacatg
    43441 gaaagtgata accatgccaa gcaactgaat ccagcgattc tcaggtaggg cagccttccc
    43501 tgcttttttc cgttccttat tgagcgtttt tttcttgcga acccaggcat cattgatgac
    43561 caagcctagt ccatgaaaga gtccataggc gatatagtac caggtcacac catgccaaaa
    43621 tcccataatc agcatattta caatgtaggc catgcttgag gttacattac gatttttaaa
    43681 gactttcttt ctggttaaca ccatcaccat tcgcataaag acaaagtcac ggaaccagaa
    43741 ggacagactc atatgccagc gattccaaaa ctcctttaaa tcccttgata aaaagggctt
    43801 gttaaagttg atagggctac ggattcccat caagtttgag atggccaaag caaacataga
    43861 ataacctgca aagtcaaaga agagctccag accaaaagta tacataactg ccaaggcata
    43921 gagattaaag aagccacctg actgcaaggc taaattcttc agaggaggta gtaaggtctc
    43981 tcctaaaaca tgagctagga taaacttata caaaaagccc cgcatgatat agcggacaga
    44041 ttcatccagc atatccatca actcatctcg ctcaggaatg gcctgataat tttcattaaa
    44101 tcgcttaaaa cgatcgattg gaccactcga gaaagttggc atgaagagaa ggaaacggag
    44161 gaattcccag agggtaaaat ccttaatcac tccatctctc agctcgatga taatcccaac
    44221 cgaacgaaat gtcaggtaag aaattcccaa gaacccaagc aaagactgcg ttccattgat
    44281 agctggttgc accttgacaa agataatcgg aagtagggac agaaaactaa ctaagtagaa
    44341 gacccacttg ccatccttgc tttttcgata atgcttgtag aaaagcagga gcaatatttc
    44401 ccagcaaagg taaataccca aggcagctag ttgattggtc tttccaccca ccaacatggt
    44461 gacaataaag aagagactta ccaacacttc ataccaggca aagcgtttct tgaaaaagag
    44521 acctataaag atgggcaagg ttgcagcaat cacataaaca aaatactgag gattgccata
    44581 tggctctaaa tgaggaagct gttgaaaaaa ctccatcatc tcttattcac ctcgttaatc
    44641 aatcctttga tgtcaatctt tccatttgga gttagtggca aactgtctcg gtaaaggaat
    44701 ttagatggca tcatgtagga catcatgatg tctgtcaggt cttccttgat ggccttggta
    44761 atatcgatat ctcgctcaaa ctgctcacga acaccgtctt ttaagatgac ataagccaat
    44821 agattttgta ccttgtggtc cttgttatag cgcggtactg cgacagcaga ttcgataaag
    44881 cgagacttgt tgaggttttg agagacatct tctaactcaa tgcggtaacc gttaaactta
    44941 atctggaagt ccatgcgtcc gccgtagaga agcaagccct catctgtcat ggttcccaca
    45001 tcgcctgtgt gataggctgg cagaccttca aactcaaaga aggcttctgc tgttttttca
    45061 ggattgttca tataaccttt tgaaacagct ggcccagaaa caatgatttc tccctgttcg
    45121 ccatttggca gtttatttcc ttcctcgtca atgataaagg ttggagaatc agccttggta
    45181 tagccgattg gtaggcgttt gagagtcgct aacatctcgt ctgtaacagc aactgctgac
    45241 agagctactg tcgcttctgt tgggccgtaa gcattgatga tacgggcatt tgggaaacgc
    45301 tcgcgcagtt tttgagctgt tttgaccgtc aattcttcac catcaaagta gaaatgcgtg
    45361 attccaggca ttttctcact gttgaagtat tcagacaaca tggccatatc tgcaaaggat
    45421 ggtgttgatg tccagatagc gattggcaat gaaaagatag ccgcaaagag ttgcttaaag
    45481 tcctgagtga tgactgaagg aagagtgaaa agcgtaccac caagtgccaa ggtcggtgcc
    45541 caatacatga cagacaagtc aaaagaataa ggtggctgtg ccagcatttg cggacgactc
    45601 ggtgtcgcaa attccttatc cgtaatcatc cagtttgtaa agctgaggag attatcatgt
    45661 gaaatctgca ctcccttagg cttaccagtc gtaccagaag taaagataat gtagtaatta
    45721 tcatctccct tgactggatg cgtgatttca tagttgttcc cttgggcaaa ggcttcttga
    45781 acctgagcta gatttatcat tggtgtagaa acctgctcca agggaaaggc tgaaatggca
    45841 ataatcaagc ttggctctgc tacttctaaa atagctgaaa ctcgctccaa ggccgaatgg
    45901 ctatcaattg gaatgtaggc atgacctgac ttagtcagcg ctacaaaggt tgccaacatt
    45961 tcatattctt ggccaccaaa aacaaccaca ggagactttt caggcaagcc tagttggtca
    46021 atgactgcag ccaaactatc cgaatcagcc tttaaatcgc cataagtgtg ttcctgcccc
    46081 aaaacattat agacaggata gctaggctgt gtctgagcaa aatgctcaat ggtttcaatc
    46141 atatctgcta ttggtttatt tgacacaata gggattctcc ttcaagttaa aattcattat
    46201 agataaagct tccttgaccc tgaccaagat agctaaagaa gtaaagcagc cctagaaaga
    46261 taagaaaata caaggctgtc cgaccaagaa agaggtacaa ttcttttctc tgtttcatca
    46321 agaaaaacca ttcatttctg taatttttcg ctaaaataag agtgattctt actagcttat
    46381 ttttctacca ttgtaccact ttatatagta tcttttcaat tgtttaccgt atgtttccaa
    46441 tagatttcag cttattttaa ggattatgcg gtttttctat atctatttca aaagaaaaaa
    46501 gcctgagatt ttcatctcaa gctctagcaa taatagttat tttctaaact aaaaaagtga
    46561 gaatacaagc acggccaagg ctgctccgat aacagggcct acaacaggaa tccaagcgta
    46621 agaccagtct ccgtctccct tgtttggaat tggcaagatg ctgtgcatga tacgaggtcc
    46681 aaggtcacga gctgggttca aggcataacc tgttgtccca cctagtgata gaccgatacc
    46741 gacaatcaaa gttcccactg caaaggttcc gatacctgcc tgaaagtcgt aaagacccaa
    46801 agcaaagatt gtcaacacca aaacaaaagt tccaaggatt tcgctaatca agtttgatac
    46861 agtatccttg atggctggtc cagtactgaa ggttgccagg atattgcctg cattttcttc
    46921 tgcctcatag tgaggtttga attgcaacca aaccaaaatc tgacccagca tggcccctgc
    46981 gaactgggct aagatataag gcaaaacgga agcccaaggc aaaccacctt ttaaggccac
    47041 accgatggtc acagctgggt ttaaataagc tggactgagc ttgccagata caaagactgc
    47101 aaccgcaact gcaatccccc aacccatagt aatcacaatc caacctgagc tattgctctt
    47161 ggttttagga agaaccacac ctgcaacaac accatttcct agaagaatca ggattaaagt
    47221 ccctagaaat tctccaaata attcattcat catctttctg tctccattaa aaagaaggga
    47281 cgggcgacaa ggaatgctgc cctccacctc ttttattttt tcttaatttt ttaattctgc
    47341 taaatcgttg ttagcgagag ctgcttcgac atcagcacgg taagttgctt tttcttcttc
    47401 tgtccagtca tagaatcgtc ccatttcatc caaaattggc tcaacgatac tatccaagct
    47461 atcacgcata aagagcatgt gattggtacg acgaagaagg aagtcaactg ggctaagagt
    47521 caactcattg cgcattgcat agtgaaggga caaggtgtct gccaagctaa gacctggcgc
    47581 ttgttccaag ctgtgagcaa gtgcaaagac cttcggtgca tttgaaccgt aaagatttgc
    47641 taggtaatga gcttccttgc tatccaaacc acgtgaaact ccaagttgcg caaaggcttc
    47701 gatttctgaa tccacatttg ctgggttcaa ttctccacct gaaacagggt aagttttaga
    47761 attgatcaat ttaaagctac ggtcaaattc tgctttgagg atgtcaacca cgcgctccat
    47821 agctccttca gccatcttac ggtagtctgt gattttacca ccagcaagag tcaagagacc
    47881 attgtcatca cggtccaagc tagacccacg agaaactgca gatggatcca aatgtttctc
    47941 agatgtgcta ctttcaagct tgctgacagc agactcaaca tcttcacgtg ttttttcttt
    48001 ggagagataa gattcaacag tcgcaatcaa gttgtcaaag ctttcatcac tgatggtacc
    48061 gttatttcca ccattatagt cagaggcact gttccctgca atcaatggac gaagacctgc
    48121 ccagctgctt tcgatatcat caatggtgat gttggattct gggaagcggt tgttgacaat
    48181 gccaagtaga taatctacat cttcttgagt tacttttgga tgctccaaat cacctgtgta
    48241 gtctgtatca gttgtaccaa agtaagtctt gttttcacgt gggagaacaa agaccatacg
    48301 accgtcaccc aaacctgtgt cgaagtaaac tggctgtgaa accttgattt tacttgaatc
    48361 cactaccaag tgaactccct tagttgggcg catttgtgag aattgcgttc ccttattaga
    48421 caaattacgt actttatcac tccaaggacc tgttgtatta ataaccagac gggccttgat
    48481 ttcaaatact tggtctgtca agagatcacg agctacaaca cctgtaatct tgccactttc
    48541 gtcaaagagg aagccttctg ccttcacgtg gttggcaatg agggcaccgt cttggttggc
    48601 acgtttgatg ttttcaatca cgagacgcgc atcgttgtta cggaagtcaa gatacactcc
    48661 acctcctacc aagccttcct tcttcaagtt tggctggcgt tccaagactt ctttcttgct
    48721 caaaaccttg ttcgcagttg gtgtgttgct cacacctgct aaaaggtcgt acaagtccat
    48781 ggctacttta agacggaaga ggctaaaggt tgctccatct tcatcgtaaa ctggtaagag
    48841 cattggatct ggttttggaa tgtgtggagc gatttgttga accactgcac gttcagaaac
    48901 cgtatctgag accacttcta cgtcgaattg tttgaggtag cgaagacctc cgtgaaccaa
    48961 ttttgttgaa cgactagatg ttccttctgc aaagtcttgc atttcaatca aaccagtctc
    49021 aagaccgcta gctgccgcct gcaaggctac accagctcct gtgattcctc caccgataat
    49081 caagaggtcc agggtgcgtt cctgcatttt tttaattgac aattcacgtg ttttctttga
    49141 aaattccata tttacacact ttctaaataa atcgctttat tctgccagta ttagtcgtct
    49201 acttccgcaa agacttgagt tgctttcaca gccttcttcc agcccttgta gagttgttcc
    49261 ttgcgagatt cattcataga tggctcaaag agttctcctg tctcgttcaa gagtttcaac
    49321 tcgtccaagt ctttccagta ccctactgat aaacctgcta ggaaggccgc tcctagagct
    49381 gttgtttcca agtttttagc acgtgcaata tcaatgccta aaatatccgc ctggaactgc
    49441 atgaggaagt tgttcatggc tgcaccacca tccaccttca atacttgaat ggcagtctga
    49501 gtatccactt gcatggtgtc gatgatgtca cgcacttgat aagcaataga ttgcaaagtc
    49561 gccttgataa agtcttcttt gcttgttcca cgagtcaaac caaagacgga accacgagca
    49621 ttttggttcc agtatggagc gcctagacct gtaaaggctg gaacgacata aacttcatcg
    49681 ttgttgtgag aatcacgagc gtatttttca gattctggtg aattttcaac catgcgaaga
    49741 ccgtcacgaa gccactgaat agcacttcct gcgatgaaga tagaaccttc caaggcataa
    49801 taaaccttac cgttgattcc gtaaccaatg gttgtcaaga ggttgttttc agacaactgc
    49861 atctcttccc cagtattcat gatgatgaaa gagcctgttc cataagtatt cttaaccata
    49921 cctggctcaa aagccaactg tccaaagagg gctgcttgtt ggtccccagc catacctgag
    49981 attggcacct ctccaccgta gaaatggaat ggagctgtct tgccgtagat ttcggagtta
    50041 gaacgaactt ctggaagtat agccttcgga atgttaagga tttccaaaat ctcatcatcc
    50101 catttgagtt ctttaatgtt ataaagcatg gtacgagctg catttgagta gtcagtcacg
    50161 tgagccgcac cgtcagtcaa tttccaaacc aaccaagtat cgatagtacc aaagagcaat
    50221 tccccttttt ctgctcgctc ttgagcgcct tctacatgat ccaaaatcca acgaaccttg
    50281 gtagcagaga agtaagcatc aataatcaaa ccagtctttt catggaattt ttccacataa
    50341 ccttggcttt ttagttgctc agccaaaggt gctgtctggc gtgactgcca aacgatagca
    50401 ttgtagatag gaagtcctgt tttcttatcc cagacaaccg ttgtttcacg ttggttggta
    50461 atcccgattg cctcgatttg atttggcttg acgccacttt cgatgaaagc acccgcaata
    50521 actgactgaa cagagttcca aatttcattg gcattgtgct caacccaacc tgcctgaggg
    50581 aaaatctggg taaactcttt ttgactcgag ctaacctttt cccctttttt gttgaaaatg
    50641 atggcacgag aacttgtagt tccctggtca atggccatga tgtatttttc ttgtgacatg
    50701 tactgtcctc ctgataaaga tcttgaggtg tttcctcttt acacttacta gtatacaaaa
    50761 taaagcgctt tcttttttat caactttttt taatttttaa aaaaatgtga ggagattgtg
    50821 tgaatttcac aaaaaagacc tggattaacc aagcctttta agtgaataat aactgacgaa
    50881 tccctgccaa atcttccata tccaagtcat tttttaaata atagactggg gtctgttcct
    50941 tcttatgaat cgggttattg gtaaccagca aatcataatg ccgactaggg tcataagctt
    51001 caatggtaat aaaacgattg tattccaaat accgtttcaa aatggctgcc atccttgaaa
    51061 agacaagaaa accagatgtc aaatccagac caatccgcat atgctggcca ccgttttcag
    51121 ccatatattc gattaactgg agccattccc agagaatctt cttatctaaa tctgtcccct
    51181 gttgaaaagc aggtagagca tgaaaaatct cctctgctgt ctctttaaaa tcatgttcca
    51241 tcagtaaata tggatgacga ttctctaact ggtacttgta gcgatcctgt aaaatatagc
    51301 ccttatagag atagacttga gcacaaagct gactgagttc ataggtgaca tggtcctctg
    51361 tataatcccc caatagttcc tccttcttca tttcttgaat caattgcgtc agtaaatctg
    51421 ccaactgccc tccaaaacca agaatatatt ccatagtatg aagaggaaga atgcgatgag
    51481 ataggagaaa agagaagaat atcatcatct caccatcctc aactcctagt ggaatatgtt
    51541 gcccagcaaa aaaggacgga acctttctca gcaaacgaag atagaagata ttgtcaaaat
    51601 accctcgcat tttctcttct atgacttgaa actgacaagc attgacccga agacgttgtt
    51661 gactgatgtg agcccagaga accaagtcca atttctgccc cacagacaaa cttgcaccgc
    51721 agatttcctc taaattggca atctcctgtt ttctctctgg tttctgcatg tgaccttccc
    51781 attcctgact cgaccagacc tttcggaaaa gacagaaata gaaatagcga atctgatgct
    51841 ctggacctcg ccaacgtcca ttttggatgg ataaatcaaa ttctgacaaa atctgattta
    51901 aaccagccaa gtgacgacca agcgtagcct cgctaatcac caattcttga gccagctgat
    51961 gggctaaaaa ctgttggtgg tagagaagat aaaccaaaat ctggtattta acagcactct
    52021 ccaaaaacaa gctccgaata tctctcccct tggtagctgc accgatagac agacgcagat
    52081 tttcatcttc tgagtgaata gccagctcta agccactatc caaagccttg tcattgagca
    52141 gggtgacata tttggttagg gttgcttttg aaaatcctgt ttcttccatt acagccttga
    52201 cggtcgtctg agactcttgt aatagaaagg aaaggattga aaattgacca cactcggctt
    52261 tctccatcaa atctcctaaa tacatttgtt acccctttca ttttctacct taagcatagc
    52321 ataaatctta caaatgctaa aataatctgt ttctcttttt attttcatgc tgatttcctg
    52381 gtccattatc ctgaaaatca gtaaacacac ggctccccct ttgggcattt ttatgctaaa
    52441 atagtagcta tggataaaat tattaaaact atatcagaaa gcggagcctt tcgtgctttt
    52501 gtccttgata gcactgaaac cgtccgcact gctcaagaaa aacatcaaac ccaagctagc
    52561 tcaactgtag cgcttggtcg aactcttatc gccagccaga ttctcgcagc caatgaaaaa
    52621 ggaaatacca aacttacagt taaggtgttg ggatctagct ctctaggtgc tattatcacc
    52681 gtcgctgata ccaaggggaa cgtcaaaggc tacgttcaaa atcctggtgt tgacatcaaa
    52741 aagactgcga ctggtgaagt cctagtcgga ccttttgttg gaaatggtca attcctcgtt
    52801 atcacagact acggtactgg aaatccttac aactctataa ctcccctcat ctctggagaa
    52861 atcggtgaag accttgcctt ttaccttact gaaagccaac aaacgccttc agcggtcggc
    52921 ctcaatgtcc ttttggacga ggaagacaag gtcaagattg caggtggttt cctagttcaa
    52981 gtcttgccag gagccaagaa agaagagatt gctcgctttg aaaaacgcat ccaagaaatg
    53041 ccagctatct ctactcttct cgaaagcgac gaccatatcg aagccctcct caaggctatc
    53101 tacggggacg aagcctacaa gcgtctttct gaagaagaaa tccgtttcca atgtgactgt
    53161 agccatgaac gctttatgaa cgctcttgcc agccttccaa gctcagactt acaggaaatg
    53221 aaagaggaag accacggggt agaaatcact tgtcaattct gccaaactac ttacaacttt
    53281 gatgaaaagg acctggagga actcattcgt gacaaatctt aatacacctt ttatgattgg
    53341 caatgttgag attcccaatc gtaccgtttt agcgcctatg gctggcgtga ccaactcagc
    53401 ctttcgtacc atcgcaaaag agctcggagc tggactcgtt gtaatggaaa tggtctctga
    53461 caagggaatc caatacaaca acgaaaaaac cctgcacatg cttcatatcg atgagggcga
    53521 aaaccctgtc tctatccaac tttttggtag cgatgaagac agcctagcac gcgcagcaga
    53581 attcatccaa gaaaacacca agaccgatat cgtcgatatc aacatgggct gccctgtcaa
    53641 caaaatcgtg aagaacgaag ctggtgctat gtggctcaag gatcctgaca agatctactc
    53701 tatcatcaac aaggtccagt ctgtccttga tatcccactt actgtcaaaa tgcgtaccgg
    53761 ctgggcggac ccatctcttg cagtagaaaa tgctctcgct gctgaagctg caggtgtttc
    53821 tgccctcgcc atgcatggcc gtacccgtga acaaatgtat actggccacg cagaccttga
    53881 gaccctttac aaggttgccc aagctctaac caagattcca ttcatcgcca acggtgatat
    53941 ccgtactgtc caagaagcca agcaacgcat cgaagaagtt ggtgctgacg cagtcatgat
    54001 tggccgagct gccatgggaa atccttacct cttcaaccaa atcaaccatt actttgaaac
    54061 aggagaaatc ctacctgatt tgacctttga agacaagatg aagatcgcct acgaacactt
    54121 gaaacgattg attgacctca aaggagaaaa cgtcgcagtt cgtgaattcc gcggcctcgc
    54181 tcctcactat ctccgtggaa catctggcgc tgccaaactc cgtggagcca tttcgcaagc
    54241 tagcaccctg gcagagattg aagccctctt gcaattggag aaggcttaat agtttaaaac
    54301 ccgtaactct cttaaagagc ctcttgaatg ccgccattct ttcctcatca aaaaaactcc
    54361 gtagtctcta gcgctataaa tccggctaga gattacagag ttatttttta atctaaactt
    54421 cctacaaggg tatattatct actgaaagga tatggtattt gtagggaata ctttaaagag
    54481 ttcttacagg aagtcagtat taactagtta tattaggttt agtttaccca ttcaccattg
    54541 gcattgactc tatagctatc tacagttgtg ttgactgcaa gggcacctga gccattgaca
    54601 tagtaccatt tatctgatac tttgaaccat tggcttgctt tcatagcacc tgatgcttca
    54661 agatagtacc aggtatctcc atctttcacc caatctgttg ccattgaacc gttagcgttg
    54721 aggtagtacc atgaaccatt gttttggagc catcctgttg ccattgaacc attagcgttt
    54781 agatagtacc atgaaccatt gttttggagc catcctgttg ccattgaacc attagcgttt
    54841 agatagtacc atgagccatt gttttggagc catcctgtcg ccattgaacc atcagtattg
    54901 tagaagtacc acataccgtt ttcttgtttc cagcctgttt ttggagtaga tggttgtgct
    54961 ggtttttcag tttttggcgg ttgctgttga gtcaagcgat tatattcttc ttctgatcta
    55021 cgagcatagt cttcttcagc ttgttgatca gctggttttt ctgcttttgg ttgttcagct
    55081 ggattctctg gttttggagc tggagctggt ttttctggtt ttggagctgg tttttctggt
    55141 tgaggagccg gcgctggttg tggttgttca gctggttttt ctttaacttt atcttcttct
    55201 gctgcttttc gtttagcttc ttcttctgct tttttacgat ctgtcttgat tttttctaac
    55261 cttgtagcct cagcttgttt actctcaact tccgcttttg cttgcttaac tttttcctcg
    55321 tttcgaggtt ccttagcttc ctcttttact agttcaagct ccgctttttt aacttccaca
    55381 tcggactcag caatttcaag ttcaagcgtt ttgtaagtat tggttgggta gttacgacga
    55441 tcttcttctt tttgatcctc ggcttttttc ttagcttctt caaccttctt ctcagcttct
    55501 gcaacctttt tttctggttt cagggatggg cttggaagag tttcttcacc tacgctagaa
    55561 tctgaagact tcgcatcatt ttctttttta tcaggtgttg ctggctctcc aagaactcct
    55621 cgttttgtcc gcttctttgg ttcatcttta actttagctt cttcttctgc ttgttcacga
    55681 tctgtcttga tgttttctaa ccttgtagcc tcagcttgtt cacgatctgt cttgattttt
    55741 tttaaccttg tagcctcagc ttgtttactc tcaactttcg cttctgcttg cttaattttt
    55801 tcctcgtctc gaggttcgtt agctttcact tttactagtt caagctccgc ttttttaact
    55861 tccacatcgg actcagcaat ttcaagttca agcgttttgt aagtaatggt tgggtagtta
    55921 cggcgatctt tttctttttg atcctcggct tttttcttag cttcttcaac cttcttctta
    55981 gcttctgcta cctttttttc tggttctgtt gataatgtat cttttttaaa ctgctcaaaa
    56041 gctgcggtta actcttcttt tgtttctttt gtttttgacg tcaactcagc ttccgacttc
    56101 tcttctaaaa catttaattc atacaaatac ttcgttttaa ttttgctcaa ctttttgttg
    56161 aagtcggcat tttgggtatg ttgaactttt ttcaaatttt tattgacatc cttcaatata
    56221 ctttgtagat gcgactcgac ttcatcagca tacttcttcg atatatcttg cccactagat
    56281 gtaaccgtgg agttattccc acttctaacc ccttctgcat ggactactcc tcctaagaac
    56341 aagctggcaa ctactacact agctactcca atactaaatt tacgaattga ataatgtact
    56401 tttctttcgc tttttgatgc aaacataatt atttccttct atattttttc tttaacctta
    56461 ctatatcact tcaatatgaa ctgtatataa atcgaatttt gtatttatct ctttatgctt
    56521 ccatttggga ttataacttc atgtaatagc ttttcctctt cagctattcg tcgatacaaa
    56581 ataactgcat aaactggaaa aactaaaaca aaagtcacat aagcatgact caacaaggtc
    56641 aagccaatca actcaggaag aatatttaaa aagtaattag gatgttttac tgtcctaaac
    56701 aagatatgat ctacatattt gtgattattg acaagcataa gcttcactgt ccaaatatct
    56761 cccaacaagt gaatcaccaa cattaacatc agcatagaaa aaataagcaa gactaaacca
    56821 accatgccca tgccatcaaa aattgtcttg tgcaccattg cctcaaccaa gcaagagaga
    56881 taaaaaacaa tatgagccat agttaatcgt tttgtattct caactccaaa ttctttcccg
    56941 ccattgctaa ggattcgttt ctcattctct atcgaacgct ttaaaaaaat caatcgaata
    57001 aggaatgtta ctaaaataat cgctaatacc atattagtat cctttctttt atctacacaa
    57061 agaataacac acttatgtta accctatatg aactttaata aaaaactaat ctgtctacaa
    57121 gctaatctta aattccatac cgtgttcata agggagaaaa ctataatcca tttgatagct
    57181 ttctaaaata ttattcacaa tgtaaagacc caaaccggaa ctttcatcct tatctgtcac
    57241 gatttgagaa tgatagaata tatcaaataa atgttctagt tcttggtcac ttagaggcgc
    57301 acatgtattt ttgatagaga gatagccatc ttgctcggat atgattacgc gcccattttt
    57361 atctgaatat ttaattgcat tactaatcag gtttgtcaaa accttatcca atgccctaag
    57421 actcatgacg accctggtag catctgtcaa ttgattttca attgtaacac ctattgaatg
    57481 agctaattct tgataacgtg ataaaatatc tactaaaact ggcttaacag tcaaggtctc
    57541 acgacactct gtccactctt ggaatttaga agactccagt acttcttcca ataagtggct
    57601 catctggtca atcttattta tactctttgc aatatatttt ggatgatctt tgtaatctcc
    57661 aatattatgc tgcatattct ctaggataat tctaagactg gctaaagggg ttttcaactc
    57721 atgtgatgct ccgcggacaa aggaaacctt ttgattttgc aattttacaa tttgctcatt
    57781 acgactttcc aactcatgaa taaccttcaa caagtgctca tacataccat taatctgttt
    57841 tccaacttca ccaacttcac caacttcatc tttcctactt tcatcaaaac gaatattgtc
    57901 atccaaatct tgcattttac tagtcacttc tgaaatgtaa aaaagaggat tgagcaagcg
    57961 tttagtataa aaataagaaa aaacaaagga aaaagcaatt gtaaccaaaa atgtatatgg
    58021 gagatacaaa agcaaaatat tctttgcttc tttgtagaca tccaccccgt gaacaaattg
    58081 cacggttacc tgtttaccat ctgctgtact aacagacata tctaacatca cgatataatt
    58141 tgatagcttt ccatctttaa tatccaagtc atgcacaaga gggagccgct tatctacaat
    58201 atctctttta aggtgagcag atatggtcaa ggactttgaa taagactgga gtaagcttgg
    58261 aatttcatca gatgtcttag tctttaaata ctccgtaaac actcttgcgc tctcattaaa
    58321 cttttccccc tccagttgaa tataataaaa aggaaaggtc aaataaatag ctatatgaat
    58381 gactagacca acaccaccta gaattgcaaa acttcttaaa aaagacttgg ttaataattt
    58441 aggatttttt atcataagct aatcttatac ccaacatttt tcacagtcac gatacaatct
    58501 aaagctaatt ttttgcgaag agtacgaata tagacatcaa cgaccctatc acaaggtaaa
    58561 tcagctacat cttttgaaat ttcttccaat atctgctctc tacttaaaac ttgattttta
    58621 tgctgaatca aacactttag taccagtaat tcctttggct tgagatcaat ttcttcattt
    58681 ttataatgtg ctttgtaaga ggtaaaatcc actgttacat cctgatatcg ccaaatatcc
    58741 tctatgacgt agtaacgtct gataagcgcc ttaatacgct tgacaagcag taccaaagaa
    58801 aaaggttttg tcacatgatc atcagcatag agatcaaata cctgtgactg agtagtttca
    58861 tctcccagag cactcaagac gatgacagga atatcgtgct tttgattgat ttcttttaac
    58921 acttcaaaac cactcttcct aggcatcatt aaatccaata ccatgagatg gatagggaga
    58981 tcttgaaatt tttccaagac ctcttgtcca tccttagcca taatgacatg ataaccctct
    59041 tctgtcagaa atgctgcaat tccttctcta atcatttcct cgtcatctgc aactaaaatg
    59101 ttcatctctc tccctttcta ctaccagaac tccatacatc tatttcctgt atgctatttg
    59161 aaaatttcct accagcctat catctatgat aatagaatgg atttcattta tccgctactt
    59221 tttgtcaaca acaacgtcaa tacaagaaaa tcattcatct tgcagcttat actcttcgaa
    59281 aatctctcca aaccacgtca gctctatcta caacctcaaa acagtgtttt gagcaacctg
    59341 cggctagctg cctagtttgt tctttgattt tcattgagtt tcactccact gtgacttatg
    59401 gtcagatgct gatactttta ttcttttatg caatatcaaa ttttaactgg cctgctttga
    59461 caccaatctt aagtgtgctg cctgccacta aatctccctt aagaagaagt tctgccaact
    59521 tgtcctccac ttctgtttgc agggttctgc gaagtgggcg agctcccatc tctgggtcat
    59581 atccttgatt tgctaacaat ttcagagctg aagcttgtaa tttcaagtca atgccttttt
    59641 cagccaaact tgccactaaa ggcttgacca taatcttcac cacttcctgc atatggtcac
    59701 tagataggct atggaagacc accttctcat caatacggtt gatgaattcc ggtctataag
    59761 cttttttcag ttcttcaaac atgcgttttt ccatattttc ctggtcaaaa cgaatatcct
    59821 tagccccaaa accaacagtc ttatcatcac gaagggcagt cgcacctagg ttcgatgtca
    59881 taatgataat ggtatttgaa aaatcgacct tgcgtccctt gctatctgtc aagacaccgt
    59941 catccagaac ctgcaagaga acattaaaga tatctgggtg agccttctct acctcatcaa
    60001 agaggagaac ggaatagggt ttattgcgaa ccttctctgt caactcccca ccttcttcgt
    60061 aacccacata gcctggagga gctccattta gacggctggc tgcgaatttc tccatatact
    60121 cactcatatc aaagcggata agggctgatt cgtcatcaaa gagaacttct gccaaagcct
    60181 tggccaactc ggtcttaccg acacctgtgg gtcctaggaa cataaaggaa ccgatcggac
    60241 gcttgtgact gcgaattcct gactgattac ggcgaatggc acgactaata cttgaaacag
    60301 cttgatcttg accgataacc cgtttatgga gttctgcttc aagatttaga tatttcttag
    60361 cgtcagtctg agtcagtttt tgaactggga ttcctgacaa gcgactcaag gtggtcaaaa
    60421 tatcagactc tgtcaccaag tctttgtaga caggtacttc ctcttctttt gcgattagct
    60481 gggctgcctg tttccacttg ccatccatca gggccttgtc agctggactc aaatctgaat
    60541 cgtctgcttt tacatacttt gccttatttt gcactgttgc tgctgcttcg tccaagaggt
    60601 cgatagcaga gtctggcaag tgacgactgg ttaaataacg atgagccatc ttaaccgctg
    60661 tttcaaccgc ttcatctgtg atttgtacac ggtgatgttt ctcataagtc gccttcaaac
    60721 cttgtaaaat agtcatacta tctgccacac ttggttcttc aatcgtcact ttagcgaaac
    60781 gacgagaaag agccgcatct ttttcgatat gtttttgata ttcttcctga gtggtggcac
    60841 caaccgttct caaagttcca cgcgccaagg ctggtttcaa gatattggcc gcatccagag
    60901 tcgaatcaat tccgctacca gaacccatga tggtgtggag ttcatcgata aagaggatga
    60961 cttggccatc ttcttcaata tccttgatga tattattcat gcgttcttca aagtcaccac
    61021 ggaagcgtgt ccctgcaacg acattcatca aatcaagttc taacacgcgc atcttagcca
    61081 tttccgcagg cacgtcacca ctagcaatac gctgggcaag accaagggcc agagctgttt
    61141 tcccgacacc agcatcccca accaagacag ggttgttctt agtcttacgg ctcaagattt
    61201 gaatcatacg tgagatttcc ttgtcccgac cgatgactgg ttctaacttg ccagaacgcg
    61261 cttgctctgt caaatcatgc gtatagtcct cgagaccacc actaggagtc tgcggcatgc
    61321 ccatcatatt ggccatagaa ttttgcttgt cagctactgt acgatggcgt tggcgtaaag
    61381 ccttgagatc ttcacgagtc cagcctgcac gttcttctaa atttcgacga agggcagcaa
    61441 tcttgacctg atctttcttg tcttcataag aaaaaccagc cctctccaag atacgagtcg
    61501 ccaaggcatt gccatcatgc aaaatcgcat agaggacgtg ctctgtccct agtaccttag
    61561 catggaccac tgacgctaca tactctgctt catcaaaaag aacctgcaaa cgacgggaga
    61621 acggcaattc cgtaaaggtt tcatcctggc tatagtccgt ttcagtcagt tccaaagcca
    61681 cctcttctaa acggtccatc tcatacggat aatcatttaa agttgcccct gctacactat
    61741 aactgtgatt agacatggca atcaacaagt gccacgactc tagataacga gctccaaaat
    61801 gtccagcaac catgtaggca ctttcgatac attcattcaa tgcttttgaa tagttcatct
    61861 tacttccctt ttctatctac ctcttgtatg acctgacgta gcatgtttgc tcgaacaact
    61921 ggagcttctt ctcctaaaac gcgatccaaa gctactgatt ctagcaaatt catctcctgc
    61981 ttggtcatca attcctgctc aaccaaaagc tggagaatat cctcataaat ttcttgactg
    62041 actcgctcac caatcgagta aagcagatcc cggagcattt catgatgact agaaaactca
    62101 atccgtccta tacgaatgta gcctccgcca ccacgcttac tttcaaccaa gtagcctcta
    62161 ctttccgtaa agcgtgtctt gatcacgtag ttaatctgac taggaacaac ctgaaaggta
    62221 tctgccaact gactccgttg caactccacg ataccagatt gatctaaaat cgccttgatg
    62281 taggcctcaa tatgatccga tgtattttta aatctcataa caaacccacc tctctcttta
    62341 aaccttgacc ttgtttgact attataccga aattttctca tttttaaaag aaaaagggcg
    62401 ctggtaaagg ataatcttca ccaactccct atttttctac ttatctaagc ctaattctgc
    62461 caagatttga cgtttgtagg caatcttttg gacttccttg tcctcatctt cagaccaatc
    62521 tagtttaatt tctgaaacaa tctgcccagg gcgatttttc aagatataga tgcggtcgct
    62581 gagattgagg gcctcctcaa tactatgcgt gatgatcaga gttgttagct gcaactgttt
    62641 gtgaatctca agataccaag cgtggagttc catctttgtc atctcatcca aggcgctaaa
    62701 ggcctcatct aagagaaaga gcttgtgccc aaaaaggtag gtccggagta aggctacacg
    62761 ctggcgcatc ccaccgctaa gttcatgagg atacttgtct cttacagctg tcagctggaa
    62821 ggtcgcaaga attttatccg ctcgggaaat agcttctgcc ttatccacct tttgaatcaa
    62881 gaggggcaga atgatatttc caagcaccgt cttgtgctcc aagagcagat ccttttgcaa
    62941 catataactc acgcgcccct tgggattttc ttcaccatca aggacaattc tccctgactg
    63001 aacttctaaa atcccagcga ttagattaaa gagggtggtc tttccaacac cacttgggcc
    63061 taggatggaa accacttcgc ctgaagtcac ctgtaggttg atatcctcta aaatcctctc
    63121 ctgaccatag gcataactga cgtgctctag tctaatttct gtcattattt cacaaattcg
    63181 ttggtgaagc ctttgtctgt caagtcttct ttaaggatac cattttcttt atcccatttg
    63241 tagaaagcat tccagcgagc tgcgtcaaat tgaccccatt tttccttgtc gcttgcgtat
    63301 tcttttgaca agtatttttg agattcgatg acaaagtcac gtttttcctt gagttcaggt
    63361 gcattcttga tgagaatatc tgcagcttct tctggatgtt ccatggcata ttggtagcct
    63421 tttttgatgg cttggatgac tttgcgagct tcttctttgt tatctttcag atagtcgttg
    63481 tttgcgatga taactggtga atagtagtca aactccttga catagtcttt caagtacatg
    63541 aagttagcat ctacaccttg agatttagca aggatgccat cccaaccgta gtaaatccaa
    63601 gcagtatcaa agacgccatt ggcaatcggt gtgattgagt ttgagtcgtt atttggtact
    63661 ttttcaacct tctcaaagtc tccaccttga gattctacca aggttttcaa catagcaagt
    63721 tcagttgggt cattccatgt cccatatttc ttaccaacca agtcttttgg actgcttaca
    63781 ttatcagatt tacgagagat gattcctgat gtattgtgtt caacaatagc tgcaacggca
    63841 gtgattcctg ctcctttttc caatttctta gccatgtagt cttggaaata cactgcaaat
    63901 ggtgcctttc cgttgataac caagtcagaa gaactttctt ctggtggcaa tttcaaatca
    63961 acatccactc cagcttcttt gaaataacct ttttccttgg caacataaag ccctgtgtgg
    64021 ttggtatttg gtgtccagtc taggataaag tcaaccttct taagttctgc ctctttgttg
    64081 tctttagaag cagttccttg accacaggcc acaagcacaa cagctacaag agctgttaca
    64141 agcgttaaaa acactttcca tgttttcttc attttgattt cctcttttct ttttcagaaa
    64201 cattctaatt ctacgaacgt ttccatttaa tcacatattt ttcactgata tcgaccagct
    64261 tcatacccaa aagactgata atcgacacca gaataataat ggcaaacatg gtatcatact
    64321 gaaacagttt tttagactga atcatataaa caccaagacc ttcaaaacct cccaaccact
    64381 cagataccac agttgtgata aaggcgtagg agacactgac cctcagacct gcataaaagt
    64441 aaggcaggct aactgggatt ttaaaatgcc acaggatttg ccaaggcttg gcccgcatca
    64501 gactaaacaa ggtcagcata tccttgtcgc aatgcctaaa accgtccaaa atactaacga
    64561 tgatgggaaa ggttgtcgtt aagataatca agacaatctt gggcaaaatc ccataaccta
    64621 gccacaagac caggatagga gctatggcaa tggtcggaat ggtctgaatg accaccatca
    64681 tagggtaaat caggtcattg agccaagtca aactatccat gagcacagcc ataagacagg
    64741 caatcaaaac tcccaaaatc agccccagta aagccactct caaggtcgcc cagctatggt
    64801 gccagagaaa ttctctgtca cgaacaaagg gctggagaat ttcaagaggt gtcggcagga
    64861 taaacttggg gagaagttta agaaaacctg ctaactgcca gattgacaat actccgagaa
    64921 agcccaatag actaatgtgt cgtctcagta tacttctcaa gtttctcatc aatacttaaa
    64981 atctctccta catttatttt gacattggca aagacattgt ctgcctcctg ccctgccact
    65041 tccagcgctt cttttagaat gcgcataagc tcatcaaact ccccttccaa gaccgtttca
    65101 aatggtgtca ctaccatcgt cacttcttga gtttgcagat aagcaatgac ctgatcaata
    65161 acagctatcc gatcaatccc ctgtactagg ggtaaaactt gcaaggcaat gcttgctttc
    65221 ataagaacct cctcttctcg ttttcctttt taaaaaaaga aaaaccttta ccatacatgg
    65281 aaaaggtgca aaattagact aagtatcgtt ccctccgctg gcattaccca gatcaggtgc
    65341 ggtcgaagtt taacacttcc tctcagactg tacacagact cccatatatt atatgtatat
    65401 atgatagcgc aaaataagaa aaatgtcaag gaaactgctt acagaaaaga gcaggaaatt
    65461 tctcctactc caattttcta tactcgttct ccatcactgt ttactctgta gccatccacc
    65521 gtcgtattaa cagctaaggc gcctgaagag taagaataat accacttacc agagacctgg
    65581 taccagcctg ttttcattgc ccctgaacta cccagataat accacaaacc attttccttt
    65641 aaccatcctg tctgcatttc accagataat ttcaaataat accagctaga accgtctttc
    65701 agccatcctg ttgatttaga accatttgat ttgaaatgat accaactacc atttattttc
    65761 ttccaaccga cagttgaact actatgggat ccatagctag agatgtttcc tgattgattc
    65821 tgataatttt gtgaagaagt cactccctct agctgtatat agcgacgact tccgttataa
    65881 gccgtataac tcaaccactt gtagccgtct ttttcgagaa tttgatcata atgaacgttc
    65941 tctccaggat aatagtaatc aatcacagtt gcactaacta ggggttcagt tttgatagca
    66001 gacttggtct taaaataatg agttccgcct gttgaagaaa gaacagaatt acctagagga
    66061 tttttattca cagcctccaa ttgaacataa cgatagcttc cattataggc agtataactc
    66121 aaccacttat agccgtcttt ttcaaatatc tgatcataat gaaccttctc cccaggataa
    66181 tagtaatcaa tcacagttcc gctagctagg ggttcaggtt taatagcaga cttggtctta
    66241 aaataatgag ttccgcctgt tgaagctgag gattgactat tcccaacgct gccgccatcc
    66301 aaatctttaa aatgaataaa tcctgtcatc gtgtttgctt ttataactcg tttattatag
    66361 gattctgtat aaccatagtt atattcctca atctcaatct gatctcccat tacatttgac
    66421 acccaggcaa catgaccata agttcctgca gtagaccaag taatggaacc aatcgtcggt
    66481 gtattatcta cacgataacc ttcccgacga gcacgatgtc cccattcatt cgcatttcca
    66541 taagctgccg gcatttcaaa accattgaca ttactcaaac gaaaggctac aaaagaagta
    66601 cactgacgag aatacatgcg ccactgatca atctcctggc tcccattttt ataataagca
    66661 ggataatcat ccccacgcgc aatcgatcca tttcctctgg aataggcata gacactatca
    66721 ccagctgcta gcatcaatcc tactactaaa aaaggaacaa gctttttaac tgacatcttc
    66781 aagtaataac ttgttcctct tgctataaac ggtaaaattt tcattcttcc tccttgaaaa
    66841 ataatataaa gcgatgattg ccttcaccta aattattcgg agaaaaaaga aaaagtgaga
    66901 aaatttctca ctttagtcaa gataatgaat caaattcttt tctgtaagaa tatctgagta
    66961 agtaaaggat tcaacgtaaa cattaacttg tttatctcct tccacatccc caaactccac
    67021 aataaatagg gatggataaa cttcaattag cttacccaat ctattttttt ggcgcttacg
    67081 accattctcc aaagtcattt ctacgacttg tccctcatgt gccttgattt cttctttgat
    67141 ttttttcatc ttggctacat ctgtaaatgc atctgacatc ttatgcctcc ctctttgaga
    67201 tacttgaaaa tttattgtat tctttttgga aaatcaattc cactgttcca cgagctccac
    67261 tacggttttt ctcgataata acttccacct tattatttgg gataccctcc tcttcttcac
    67321 caccacgttc atagtagtca tcgcgataga gaaaagctac gatatcagcg tcctgctcaa
    67381 tagacccaga ttcacgaata tcagacaaga ccggtctctt gtcctgacgt tgttctacac
    67441 cacgagaaag ctgactcaga gcgattactg gaaccttcaa ttccttggct agtattttca
    67501 actgacgaga aatttcagaa acttcttgtt gacgattttc tcgaccagtt cccgtgataa
    67561 gttgcaaata gtctatcaaa atcaaaccaa gatttccagt ttcttgagcc aatttacgag
    67621 aacgagaacg aatctctgta atccgaatac ctggcgtatc atcgatatag atactggcgt
    67681 tagctagatt accctgagca atagtatatt tttgccactc ctcatctgtc aattgccctg
    67741 tacggataga atgtgactcc actaagcctt ctgcagctaa catacgatct accaagcttt
    67801 ccgcacccat ttcgagtgaa aaaatagcaa ccgttttgtc caacttagtc ccaatgttct
    67861 gagcgatatt caaggcaaat gctgtcttac caactgctgg acgagctgct aagataatca
    67921 actcctcctc atgaagtcct gttgtcatat gatccaaatc acgataacct gtcgcaatac
    67981 ctgtaatatc ggtcgtttgt tgcgagcgag cttccagatt tccaaagttg agattcaaca
    68041 catctcgaat gttcttaaac ccgcttcgat ttgcattttc actgacatca atcagccctt
    68101 tttctgcctg agcaataatt tcatcagctg gttgtgacgc ttcgtaagct tggttgacag
    68161 actctgtcaa cttggcaatt aaacgacgta gcattgcttt ttctgcaaca atcttagcat
    68221 aatactccgc attagcagaa gttggcacag aattgacaat ctcaaccaag taagacaagc
    68281 caccaatatt ctgtaaatca ccttgattat caaggatagt acgaaccgtt gttgcatcta
    68341 tggcatcacc acgatcggat aaatcgacca tggcttggaa aatcaaacga tgggcatact
    68401 taaaaaagtc ccgagactca atgtattctc gcacaaaaac aagtttactc tcatcaataa
    68461 agatagcccc taaaacggat tgctcagcta agatatcttg aggttgtact cgtaactctt
    68521 ctacttctgc catcagactt cccttccttt tacaatcttg tcaagaaggt gtaaacttat
    68581 ccttctttca cacgaagatt gattacactt gtgatatctt gatagatttt cactggcaca
    68641 tcaatcaaac caaccgctcg aatcggagct tgtacttgaa tatgacgttt atcaatctta
    68701 attccaaatt gcttttgcaa ttcttctgca atcttcttat tggtaataga accaaaggta
    68761 cgaccatctg gaccaacttt ttcaacaaat tctacaacag tttcttctgc ttcaagttgt
    68821 gctttaattg cttttccttc tgcaatcatc tcagcgtgag ctttttcttc cgatttttgt
    68881 ttaccacgaa gttcacctac agcttgagca gtcgcttctt tggctagatt ctttttgata
    68941 agaaagtttt gcgcataccc tgttggtact tccttaattt cgcctttttt accttttcct
    69001 ttaacatctg ctaaaaagat tactttcatt cttctttctc cttttccttt atttcattta
    69061 atacaatttc tgtcagtttt tcacctgctt ctgacaaggt tacatcttta atttgagctg
    69121 ctgccaaatt aaagtggcct ccaccgccta actcttccat aatccgttgt acattcagtt
    69181 tactacgact tcgagctgag atagagataa atccttgtgt attcttcgca agaacaaaac
    69241 tcgcttcaat acctgacatg gctaacatgg catctgctgc cttactaata acaactgtat
    69301 catagcattt cgtgtcctta gcctctgcta ttagtacatc tgaacctaat ttacgcccct
    69361 gtaaaataag ttcattgacc tcacgatatt cttcaaaatc tgtcgcagcg atttcctgga
    69421 tagcaatact atcacttccg cgcgttctga gatagctagc aacatcaaat gtccgactag
    69481 ttactcgcga ggtgaaattt ttagtatcca acatcatacc agccatcaaa acacttgctt
    69541 gcatacgact caaacgattt ttcttagaat tctggaactg aatcaattcc gttaccaact
    69601 cactggcact acttgcacca ctttcgatat aagtaatgac cgcattatct ggaaaatcct
    69661 gatcccttct atggtggtca ataacaatgg tttgggtaaa taaatcataa aattcttttg
    69721 ataatgttaa ggctgtcttt gaatggtcta caagaatcaa caaagaacga ttggtcacca
    69781 tccccattgc atccttaaca gacaacaact tcgtaactcc ttctttttct atgaatgaaa
    69841 cagctcgttc aatatctgga gacatttgtt cttcatcata aagagcatag ctattttcaa
    69901 tcacattgct ggcgaacaac tgcataccta cagcagagcc caaagcatcc atgtctaaat
    69961 ttttgtgacc gactacaaaa acctgatcta cactccgaat cttatctgaa atagctgtca
    70021 tcatagcgcg cgtacgagtc cgtgtacgct tgattgaagc agcagaccca ccaccaaaat
    70081 aaactggatt tttcgtttcg tcgttttcct taacaaccac ctggtcgcca ccacgtactt
    70141 cagccaagtt caaattgagc aaagcaactt tccctatctc atcatgattt ccatcgccat
    70201 aagaaaatcc catacttaag gtcaagggca actgtctctg tttcgactct tctctgaaag
    70261 catcaataac agaaaattta tcattcatca agccctcaag caccgtgtag tcagtaaata
    70321 gataaaatcg atccatactt acccgacgag aaaacatcat gtatttttct gaaaactctg
    70381 atataaaatt agctacaaaa ctattgattt gactaatatc tgactcagaa gttgcatcct
    70441 ccaaatcatc ataattatcc acagagacaa tcccaatcac tggtcgactt gttaccaatt
    70501 catctgttat ggcttgttcc ctggatacat ctacaaaata caaaacaccg gaagaagcat
    70561 ccatatgaac agcataacgc ttctcaccaa gcttggcata agtagacgga tttcctactg
    70621 aagccttgat aatcgtttga acagcttcta aatcaaaatc accatcttcc ttggtcaaaa
    70681 tcaattcagc atagggatta aaccactcaa cctctccaga agataaattc aatttcataa
    70741 cacctacagg catctgttcc aatagagctg tcaaactttc ttccgcttgg tggtttacat
    70801 actgtatctg ttctacatca ctccttgtat aatgcactct cagtttctta aataaaaaaa
    70861 catagcctcc tacaaaaaga aacaaaatta aaaccgtcaa cagattatta ttaacaaaaa
    70921 taatgaaagt ggataagact ccaaacgcaa tcaatcctac tagaatagga aaaattggac
    70981 ttacataaaa ttttttcatt caaaacctct tggcacccat tataccataa tacccctcaa
    71041 aaagcgactt tttaaaagtg taatcagtaa ttctatcaat tataagaaaa aggtagttta
    71101 caattcagta aacctacctt tacacatatt gaaattaaga ttctttaacc tctaacaaac
    71161 caatttcgcc atcctcacga cgataaatca cattggttgt ctgatcttca acatccacat
    71221 agataaagaa atcatgcccc aataaatcca tttgtagaat tgcttcttcc aaatccattg
    71281 gttttaaatc aatttgtttt gaacgaacaa ctttagactg gacaatattt gaatcttcca
    71341 ccaaagcatc tgtaaataat tgaccagttg ctaccttatt tttattttta cgctcgattt
    71401 ttgttttatt tttacgaatc tgacgttcaa ttttatcagt tacaaggtca attgaaccat
    71461 acatatcttg agatacatct tctgcgcgga gagtaataga tccaagcgga atcgttactt
    71521 ccactttagc cgttttttca cgataaactt ttaagttaat tcgggcatcc aactcttgtt
    71581 ctggttggaa gtacttttcg atcttttcga gtttagaaac tacataatca cgaattgctt
    71641 ctgttacttc taggttttca ccacggatac tatatttaat catatgagta ccttctttct
    71701 aaacattttt gtttttatta taacgctttc attctatttt tgcaaatttt ttcctcatct
    71761 tacaagggaa aatgttttta catccttagc accagcttct tccaacagtt tcttaacacg
    71821 atttatagtt gctcctgtag tatagatatc atctataagt aggatttttt taggaatagt
    71881 gactccactt ttaataaaga aaggaagttc tgtccccaag cgctctgaac gatttttaga
    71941 agaactggct ctctcttctc ttttctctaa taaatccaga tactcaaaac ctgctgcctc
    72001 taccaagccc tcaacctgat taaatcctct attagcatat ctatcaggac ttaggggaat
    72061 tacaacaaat tgatactctt tgtacttttt caactcctca cttaaaaatg aagcgaaaac
    72121 ttttcttaac aggaagtctc catcaaactt ataccgactg aaaaaatcct tcatagcttg
    72181 attgtaagta aaaatcgctc tatgactgac tccaactcct tctttacacc aaagttgaca
    72241 atattgacac tttgttgaca actctgtttt catacaattt ggacagttct cttccccaat
    72301 tctttcaaaa gtagaatcac agtctgaaca aagacaagag tcatcattcc tcagaagtaa
    72361 gagactacta aaagttaaaa cagtcttcat agtctgccca cataacaagc acttcataga
    72421 ccagcctcct tattcatcat ctgaatttcc ttaatcgcct tcttgattga agcatttaac
    72481 ccatcatgga agaaaagcaa atctcctgtc ggtctatcca tgcttcgtcc aactcgtcca
    72541 ccaatctgaa tcaaactaga cttggtaaac aaacgatgat tggcctctac tacgaaaaca
    72601 tccacacaag ggaaggtaac tccacgctcc aagattgtcg tactgataag tattgtcagt
    72661 tctccatctc gaaaagcttg tacttgctct aatcgatcct ctgttacaga agatacaaag
    72721 ccaattttct catttggaaa ttgctcctgt aagatttctt ctaactgctc ccctttctta
    72781 atttctgaag caaaaatgag taacggataa gctgtctttc tctgcttctc aatataggac
    72841 tttaactttg gtgacaaacg attcttgtct aagtagcgat taaaatccga taaccaaatt
    72901 ggttttggaa taatcaacgg atttccatga aaccgtctcg gtaaattcag tctttttagt
    72961 tctcctaaac ggaccttttt atctaactca ttggtcgaag tcgctgttaa aaagattctc
    73021 aatccattct cctttacact attcttgaca gcgtggtaaa gcattggatt atcaacataa
    73081 ggaaaagcat ctacttcatc cactatcagc aaatcaaaag cttgataaaa cttcaataac
    73141 tgatgggttg ttgcaacaac tagtggtgtt cgaaaataag gttccgattc tccatgtagc
    73201 aaagctatcc cgcaagaaaa atcctgttgc aggcgcttgt acagctccaa acaaacatct
    73261 atgcgaggac tagccaaaca cactgcacca cccgcattga tcactttagc cactacttga
    73321 taaatcattt ctgtctttcc agctcctgtt accgcatgaa ctaaggttgg cttttgcttg
    73381 tctactgctt gaagcagtcc ctctgacacc ttctcttgaa aaggagttaa ttggccgcgc
    73441 catttgagaa catcttgctt cggaaaatcc tcctgcggaa aatagtataa agtttgatca
    73501 cttctgactc gcttcatcag caagcactct ctacaatagt aagcaccgat gggcaaatac
    73561 cattcttcta gaatagtact attacaacgt tgacagaaaa gtttcccctt ctcctttctc
    73621 attgctggaa gtttctccgc caactgacgt tcttcttctg ttaattcatt ctcagtaaat
    73681 aaacgaccga gataatctaa atttactttc atacttcttt attcgtaaaa actagcactt
    73741 tagatgattt tttagtacaa ttaaatcatg gaatttagaa caattaaaga ggacgaccaa
    73801 gtccaagaag aaatcaaaaa atctcgcttt atctgccatg ccaagcgtgt ttatagcgaa
    73861 gaagaggctc gtgacttcat tactgccatc aaaaaagaac actacaaagc gacacataac
    73921 tgctctgcct ttattattgg agaacgtagt gaaattaaac gtacaagtga tgatggtgag
    73981 cctagtggta ctgctggtgt tcccatgctt ggggtactag aaaatcacaa tctcaccaat
    74041 gtctgtgtgg tcgtgacacg ctactttggt ggtattaaac taggcgctgg aggactaatt
    74101 cgtgcttacg ccggcagtgt cgccttagct gtcaaagaaa ttggtattat tgaaataaaa
    74161 gaacaggctg gcattgctat tcaaatgtct tatgctcagt accaagagta cagtaacttc
    74221 cttaaagaac atgatctcat ggagctggat acaaacttta cagatcaagt cgatacgatg
    74281 atttatgttg ataaagaaga aaaagaaact attaaagctg cacttgtgga gttttttaat
    74341 ggaaaagtca ctttaactga ccaaggttta cgagaggttg aagttcctgt aaacttagtg
    74401 taaacaatga ataatacagc gtttcgttga cattctcaca actactttag cgagcaaaat
    74461 aaaaagatgc gtaccaaaat atactagaaa atgaagcaat tcaaacgaaa cctgatatcg
    74521 ttttccttca cacctattta ctagaattag ctgaacgcaa tcacttgaaa attaatgact
    74581 ttgatctatg atatatagaa atcctatcgc ttcgatagga tttctatatt ttacaaatgg
    74641 tatggatagc gttatactaa agatatctta tacaaagagg tattcatatg tctatttata
    74701 acaacattac tgaattaatc ggtcaaacac cgattgttaa acttaacaac atcgtgccag
    74761 aaggtgctgc agacgtctat ataaagcttg aagcatttaa tcctggttca tctgtaaaag
    74821 accgtattgc ccttagcatg attgaaaaag ctgaacaaga tggtattctg aaacctggtt
    74881 ctactattgt tgaagcaaca agtggaaaca ctggtattgg actttcatgg gtaggtgctg
    74941 ctaaagggta taaagtcgtc atcgttatgc ctgaaactat gagtgtagaa cgacgtaaaa
    75001 ttatccaagc ttatggtgct gaactcgtcc taactcctgg tagcgaggga atgaaaggtg
    75061 ctattgctaa ggctcaagaa atcgctgctg aacgtgatgg tttccttcct cttcaatttg
    75121 acaatccagc taatccagaa gtacacgaaa gaacaacagg agctgagata ctagctgctt
    75181 tcggtaagga tggattagat gcctttgttg ctggagtagg taccggtgga acgatttctg
    75241 gtgtttctca tgcactcaaa tcagaaaatt ctaacattca agtttttgca gtagaagcag
    75301 atgaatctgc tattctatct ggtgaaaaac ctggtcctca caaaattcaa ggtatctcag
    75361 ctggatttat tcctgataca cttgatacta aagcctatga tggtatcgtt cgtgtaacat
    75421 cagatgacgc tcttgcactc ggacgtgaaa ttggtggaaa agaaggcttc cttgtaggga
    75481 tttcctcagc tgcagctatc tacggagcca tcgaggttgc caaaaaatta ggtacaggta
    75541 aaaaagtcct tgccctagca ccagataacg gtgaacgtta tctctctaca gcactttatg
    75601 aattgtaacc gtccaataac gaagtatatt gaaaaatctc cagactagag aactcacgga
    75661 tagttcctaa tctggagatt tcttatttgc acttttcttg tacaacttta gtccatggta
    75721 aataagcctc taaaacctct ttgtttacga gagtttccac gtttggaaga cattctagaa
    75781 gataggatag atatttctca ctatttataa tggattgaaa taagatatga acaaatcgat
    75841 taggacatga tggtaaagcg taatcccttg tttctcagct ttcccagaca aaaaagtcca
    75901 atagtaagtc agctgactat cactctctag caccctataa gaagtttcat ccgcatgaag
    75961 taaggactgc gtcaatagtc tctctcgcaa gaggttataa aggggctcca aatagtattg
    76021 actcgccttg atatgccaat tagcaatttc cttacgtgtg attggtaaac ccatcttagc
    76081 ccaatcttct tcttggcgat aattgggtac cttcagatta aacttctgat ggatggtgtg
    76141 agcgataata gaagctgagc caaggctatg cgccaaaggg gctttaggaa taggagcttt
    76201 cacaagctta tccagatgat tatcttttac tcgttatgga caatgctata tggcataaat
    76261 caagtacctt aaagattccg actaatattg gttttacctt tattcctcca tacacaccag
    76321 agatgaaccc cattgaacaa gtgtggaaag agattcgtaa acgtggattt aagaataaag
    76381 cctttcaaac tttggaagat gtcatgaatc aactccaaga tgttatacaa ggactggaga
    76441 aggaggtgat aaagtccatc gttaatcgga gatggactag aatgcttttt gaaaacagat
    76501 gagtataaaa agaaagtcct catttcaata gaaatcacga ctttctgatg gatttatagt
    76561 aaaatgaaat aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt
    76621 ttaaaagcag aggtgtacta ttctagtttc aatctactat atttttggag tgatagaaaa
    76681 gcccttcata agctagtcta cttgttcagg tgcgagagct ttgacatcct tttctgtact
    76741 tagccaagtc agttttccgt tctcaaagcg tttatatagt agccaaaatc cttgaccatc
    76801 ccagtaaagg gctttaaagc ggtctttacg tccaccacaa aagagaaaga cttgaccgga
    76861 gaaagaatcc aattcaaagt gggttttaac tacataggct aatgagtcta ttccctgcct
    76921 catatctgtc ttgccacaaa caaggtgaac ttgacctaaa tcacttagtt gaattatcat
    76981 agtacaatac ctttcctccg ataattattt tttatctagt atactggaag ttggggaatt
    77041 aggatagata ccttgttatg acgcgcttac tatgaatttt aagtatagtc tcctaaatgc
    77101 acttagccct tattataggg ctttttgttt taattattct aatcgagtga gactggggaa
    77161 aaaacaattt caggaaaaat ctaagcccta tacaaaaaag gaagcaattt gctccctttc
    77221 tattattagt tattcaaggc tgctgccatt gtagctgcaa cttcagcttc gaagtcgttt
    77281 gcagctttct cgataccttc accaacttca aagcgagcaa actcaactac cgaagcgtta
    77341 actgattcaa ggtatgcttc aactgtcttg ctgtcatcca tgatgtaaac ttgtgcaaga
    77401 agtgtgtaag cttggtcaac tttagtgtta tcaagcatga agcgatccat tttacctgga
    77461 ataattttgt cccagatttt ttctggtttg ccttctgcag ccaattcagc tttgatgtca
    77521 gcttcagctt gagcaataac atcatcagtt aattgagctt ttgatccata cttcaagtgt
    77581 ggaagagctg gtttattaac cattgcacgg ctttcgttgt cttggtcgat aacgtgattc
    77641 aattgtgcca actcatcttt aacgaattgc tcatccaatt ctttgtaaga aagaactgtt
    77701 ggtttcatcg ctgcgatgtg cattgacaat tgtttagcaa gtgcttcgtc tccaccttca
    77761 acaactgaaa taacaccgat acgtccaccg ttatgttggt atgctccaaa gtgttgtgcg
    77821 tctgtttttt caatcaatgc aaagcgacgg aatgagattt tctctccgat agttgctgtt
    77881 gcagatacgt atgcagcttc aagagtttca cctgaaggca ttatcaaagc aagagcttct
    77941 tcattgttag caggttttcc ttcagcaatg actttagctg tagtatttac caattcaacg
    78001 aattgagcgt tttttgcaac gaagtcagtt tcagcgttta cttcaataac tgctgcaaca
    78061 ttaccgttaa cataaacacc agtcaaacct tctgcagcaa cacggtcagc tttcttagct
    78121 gccttagcca tacctttttc acgaagcaat tcaatcgctt tttcgatgtc accgtctgtt
    78181 tctacaagcg cttttttagc gtccataaca ccggcaccag atttttcacg caactctttt
    78241 acaagtttag ctgtaatttc tgccatttta attctcctat attttttgaa aataggagag
    78301 ccgggctaag ccccgccctc ctaggtaatt actatttgta taaattaagc gttgtcacct
    78361 tctacaactt caacgatttc ttcaattgaa tctgcttgag tttctgaagc tgcaaattct
    78421 gcttcaactg ctactgcatc ctcaccttga cgtccttcga taatagcgtc agccaattta
    78481 gctgtgatca atttaacagc acggatagcg tcatcgttag ctgggatgat tacatcgata
    78541 tcatctggat cagtattggt gtcaaccatc gctacaactg ggattcccaa ttttttagct
    78601 tctttaacag cgatttgctc tttatgtggg tcaactacgt acatcacatc tgggatacga
    78661 ggcatatctt cgataccacc caagaatttt tcaagacgcg cacgttgttt gttaagaagt
    78721 gcaacttctt tcttaggaag aacttcgaaa gttccatctt cttccatacg tttaatttct
    78781 ttcaaacgag cgatacgttt ttggattgtt ccccagtttg taagagttcc acccaaccaa
    78841 cggtggttga tgaagtattg acctgaacgt actgcttctt cagcaactgc atcagctgct
    78901 tgtttcttag taccaacgaa caatacaact gcatcgttag ctgctgcatc acgcatgaag
    78961 tcgtatgctt ggtcagcgta ttttacagtt tgttgcaagt cgataacgtg gattccgtta
    79021 cgttcagtaa agatgtactt agccatctta ggattccagc gacgagtttg gtgaccaaag
    79081 tgtacaccag cctcaagaag ttgtttcatt gaaattactg ccatgagtat ttctcctttt
    79141 tgtttttttc ctcttcttga cttcaactcg caaaacgacc caagggcaac tgcttcacaa
    79201 ttcatcaaga atgagtatta tcgttcacac gacaattttc attctaccat acttttccaa
    79261 tattttcaag ctattttgat ataattttta atagggattg tcacggtaaa acctgaaaag
    79321 agggctctat tcgagtccct ctgtaaatta atctgcataa atatatgtaa caaaaccttc
    79381 agaagttgtt gttggattga accatccacg gtgatttcca attgtacgat tacctgcata
    79441 atttgattct gatacttgga tacgtgttgt tgattcaaca gctgtaacaa ccgctacgtg
    79501 accatatcca ccatcattcc aacatgcaat tgctccaact tgaggtgttg aacctgtacg
    79561 gaaacctgct gctgctgcac ttgtagccca ctgtgctcca ttaccccagt agtctccagc
    79621 ccaaggtgcc aatgttttta ctccccatgt acattctcca attggataac ttgaagcgtt
    79681 tgtactgtat gttggacgaa cttttgcacg gacaggtgct gctgcagatt cagatactgc
    79741 ttgcacttga gctgttaagt tagtgtttgc tgaagcaagt actgattgtt gttggctagc
    79801 tcgtttttct ttataagctg cttctgctac cgcagctgca cgagcctctg cctcagctgc
    79861 tgctttttgc tctaatagac ttgctttttc cccttcagct gtcgctttct cagcagcaag
    79921 acttaattca gcagctttta gttctgcctg tttcgtagtc aatgcttgag catcatcagc
    79981 caatttttgt tgattagcaa ttacagtatt gatagcatca ttatttgcta cttgtttttc
    80041 agaaatagct tttttatctg ccttttgttg ttctaacatt ttgttgtttg cagatacgat
    80101 ttcactcatt gcagcaacac gtgaaatagc ttctgtaatt gattttgagt ttacaatggt
    80161 attgatatag ctagttacgg ctccatttgt ttgagcacta cgagcttgtt tttccaacga
    80221 ttggttacga gaaacaatgt ttttagaaag ttctgtaatc tcaccctcga gtttcttaga
    80281 ttctgcttgt aatctatcat tttcagcttg caagttagac tgctcagctt gaatagctga
    80341 tacttgctcc tgaatttggt caacttgttt ttgggcttct tgttgttgtg ctgttaagtt
    80401 actaatttta ttatcttgag cagcaatttt gtcatcagtc gtttctgcat gcgcagttgt
    80461 taaaacagct acttgagaaa ccattactgt acttaataaa agtgacgcta agattttttt
    80521 cttcatatta cgtagatact ccttctttta aagacaatac tagtatacca aaaaaaggcc
    80581 taataaatat tacgcctttg ttacatttat atgtcgttct tatagataat atttttcaaa
    80641 aataaattga aaaacagtaa tccataaaaa atttaaaatc atcgtcggta ccaagctata
    80701 gactataaaa atcgacatgc tatctactgt caaccctacc ataaaagcca aaagataact
    80761 acccatttca aacaggaatg tcagcacaat catagctagc attcttgtcc aacgattcaa
    80821 caaaataaca ctattcaatt tatgaaggaa ggctcccaat aagataaata agagagttgt
    80881 aatccctatt agatggaaaa agtaaacatc ataaaccaag cctataacaa aacaatagac
    80941 taggtagaga tactctgata cttctatcgt ctcaaataag agaaatagaa aaagaaaatg
    81001 actagccaaa tgtacatggg ggaaaaatga gcccagaagc tggctaatat gggcgtcaat
    81061 tagaacaaag aaaggaagca ataaaaatac tccaactcgc ttcaactgtc tcattatgaa
    81121 ttccccacta attctatcac atctacatta tgagtatctg cactcaattt aacagttact
    81181 tctcgtgtca aatagtctgt actatgcgtt gtggcaacca cttcaccaac aggaatatca
    81241 gcaacgttaa agtttcctaa tccaccagta gtcaccttat ctcccgcact aatatcgcta
    81301 ttactattta attggctaat tttaagaacg tcattttcct tgtcatagcc aataataatt
    81361 ccataaattg tagtagagcc atgttgaatt ttaacagaaa tcttatcagc attttccgta
    81421 tttgtcagaa ggttgactat agtagagttc tcctctactt ttgaaacact cccaatcaag
    81481 ccaccatttg caatagctaa catgttctca gaagcacctt ttgatctacc tgcatctaag
    81541 gtcaactcct gcttccaaga taccggagaa cgcataataa catctgctgc taaagtcttt
    81601 gtggcttgca atttagactt catatcaagc aattggcgca gttgttcatt ttctgtcttt
    81661 aaactttcca cctcatttga tttaacttct aattggtaaa gctgtttctt caaactttca
    81721 ttttcattat atgttcgtgt caaatgagcc aaatctgatt tgacagaatc aaaccactga
    81781 aaaggttttt gtacaactct atcaaccaat gagattccat ctcctaattt tgtcacaatt
    81841 gtacttgaat aagtcgtcgc taagagagct gacacaagca gaacagtgac aaaaacaata
    81901 atgacatatt ttgatttttt aaaacggttc atatccctac ctttatatca aaaactgtta
    81961 cagtaacttt ttatcaattc ctgaaagcta ctaagatttt aagaaaaata aacaacaacc
    82021 aagtacgaga ataacaagaa tggtcagcgt atcctttaga gtccatttca attgtcggta
    82081 ttgacttctg ccttttccac cctgatagcc acgcgcttcc atagcgatag ccaaggaatc
    82141 tgcacgtttt aaacttgtcg caaaaagagg aatcaaaatg ggaatcatcg actttacttt
    82201 ttgaacgatg cttccttctc caaaatccac tccacgagct ttctgtgcat tcataatccg
    82261 cgtcgtatca tccatcaagg ttgggacaaa acgcaaactc atagacagca tcaatccaat
    82321 ttcatgaact ggaactttca cacgctttaa aggtgctaat aaagcttcga cagctgatgc
    82381 caaacttaaa ggcatggttg ttaaggttaa caaagttgaa aagaaaataa tcaatacaaa
    82441 gcgacaaaaa ataatcccag cttgttgcaa agcataatcc gtgattctca caaacgaaaa
    82501 ctcaaataaa acattcccat tagaaatgaa aaatagttga aaaatagttg tgaaggcaat
    82561 caagaaaaac atagacttca agccctgaat aaaaaatgaa agagatactc ctgacaaggc
    82621 aataaatatc cctgtcgcta taaaaagaat cagattcgtc aaggggttat tagcccaaaa
    82681 cacaatcaaa atcagtagca tcatagcaag caatttgcta cgtggatcca atcggtgaac
    82741 aatcgaatcc cctgggatat aacgccctaa aatcatacta tccatttagc gactccttga
    82801 actcctctat cttaatcggt aatcgtttaa atgacacgcc tctatcagcc aatcgtttac
    82861 aaaaggccgt aattttaggt actcccaact gaacttcttc cataaaaaca acgtcttgaa
    82921 agacatcact tggtttgccc ccctttacta aacgtccctt ttccattaca tagacttgat
    82981 tcgcatattc agcaacatca tccatcaaat gcgttaccaa gacgatggtc atccctgact
    83041 ggtggagttt tttgaacagg gtcatcaact cctttctccc tagaggatct agaccagctg
    83101 ttggctcatc taagactaat atagctggct ccatggcaag tatgcctgca atggcaacac
    83161 gtctcatttg tccccctgac agctcaaacg gactacgatc aaaaagtgat tcatcaattc
    83221 caaccagagc cagtttctca cgcgcagtct tcacagcatc ttcttcagaa actccaaaat
    83281 tttgcggtcc aaaagcaacg tccttcaaaa ccgtttcttc aaaaatctga ttttcagcaa
    83341 actgaaatac caagccaacc tgttttctaa tttgacgaat atctttattt ttagaagtcg
    83401 aggtgattaa ggtatcaaaa accctcacac tcccttgact tggcaccaat aaaccattta
    83461 agagttgtaa aatagttgat ttaccactac ctgtgtgccc aattaaagct gtataagagc
    83521 catcttcaat cgtcaaagaa acatccgaca aagctgctga agctaaggga gtaccttctt
    83581 gatatgtaaa attcacattt tctagagcaa ttcccatagc ttatcctcta gctcactttc
    83641 tgtcaaataa ttttcaggta aattatagcc attatggctc aaagattttt ttaattgatt
    83701 agcaaaagga tcgtctaatc caatttgatc taaatcattt cgagagaaaa gctcccttgg
    83761 actactagtt gattcaattt cccctttttt catgaccaat acgcgatcac tcatggcgac
    83821 ttcttccaaa tcatgggtaa tagaaatgac cgtcatatca tagtcttttc gaattccttt
    83881 tactgtccca ataagttctc tacgcccctc aggatccaac atactcgttg cttcatctaa
    83941 gattaaaata gctggtctta ggactacaac acctgcaatg gccacacgtt gcttttggcc
    84001 acctgataga cgcgctggct ctctcttttt aaagtccaac atgccaacta aatccagagc
    84061 ttcttctact ctctttttca tttcttgacg agaaagtccc tgattttcca aaccaaaagc
    84121 aacatcatct tcaacagtcg ctccaacaaa ttgattgtct ggattttgaa aaaccatacc
    84181 gatttgacga cgtatattcc aaacattttc ctcagtcaaa cgttggccat caattacaat
    84241 ctctccggat tctgcttcca gtaagccatc aattaatcga accgtcgttg atttaccact
    84301 accattatgc cctacaatcg aaagccattc tccacgtttc acgtgaaacg taatatcctt
    84361 cacatcgtag tagttctgat tttctttata gcgaaaagaa agatttttta catcaattat
    84421 tgatttcatt tcgaaccaaa tgtcccttta aatacatagg cactaccctt gaaatagtca
    84481 tagccagagt agatagtgaa aaataaggct acataaagta gaacttgacc aagcaaagtc
    84541 caatgtaata gcaagaaaat aatggcaaac atctgactaa aagttttaat ttttccaggc
    84601 attgctgctg ctaaaattgt tccaccagtt tcaaccaata aaagccttaa acctgtcaca
    84661 gctaactcac gacagataat cactgcaaca atccaagccg gagccatacc taactcaatc
    84721 aacataataa aagccgacat aactagtaac ttatccgcca taggatctgc aaatttacca
    84781 aaattactga ccacattcca tttacgagct aaatatccat ctaaatagtc ggtaatactg
    84841 gcaacagcaa agataatagc tgcaactata tgactctcta tcgaatttcc tatcgttaaa
    84901 ataaagataa aaataggtat aaagagaatt cgacctattg ttaagagatt gggaatttgt
    84961 tcttttttca ttcgtttttc cttaattttt agtaaaggtt acagtgattt gtccagtctg
    85021 agctgttaat ttcgataaat caacagtctg attatctact gtcaaatcaa caccttttac
    85081 aacacctaac gtaattgtta caggactttt agttgcaact gttgcttctg cacttttctt
    85141 ctttggcgat aaggttacac cgccctcaag ttcgctttct gaaacactga cccaacttgt
    85201 aacatctgaa actgccaatt gcaatttaac tgtttcctta cttgtcttat aagcgatttc
    85261 tacatgattt ccttcgcctg atacacttat agctgattct atactagaag aactactact
    85321 tgaggagtgg ggaacagagc tagttgaact tgttgattga accacactgt aattagaaag
    85381 agaaggctcc tctggttgag tttgaatata gttccaaaca taataagtca caaaaattaa
    85441 aatcgataaa gcaaaaagga taaaataaaa taaaggtaaa aatgatgttt ttttcttctt
    85501 tttcttactt gaacgtctac gacctgtcaa ctcatcttca tcaacatcta cttcctcata
    85561 agtaatcata ctcccagaat cataagcatc caaaacaatt tggtcatcta actcaacagc
    85621 ccatgcatat tttttcaaga aagaacgcgt gtaaaaagga cttggaagtt gatcgaaatc
    85681 gtctgcttcc attgcttcca acatatctaa ctggatttct gtctttttct gcaattcatc
    85741 taaactcaat ccctgattga ttctagctaa tcgtaaaacc tctccaattg ttttttttct
    85801 catacttgtc atcccttctt tctagtgtct attataatag gttactacga tgggaatatt
    85861 gtaaaatcaa ctatatcacc atcatctatt aaatgatgtc cagcatcaag gacatcctct
    85921 aaagtaattt cctgtaaaat tttcggcaaa tcaaaaattg tctcaccatt ttcaaaagca
    85981 tcatattgcg ttgcaataaa ttcaagagag ttcatgctac tgaaaaattc gccaaacatc
    86041 tctcttttga taatatctaa atgttcctct gtaatatcta aatcctttgt aaaattacga
    86101 atagccttcc taaattgatg agacaaagca actggctctt tcgtatccat tgtcaacatg
    86161 acaaaatgaa agcgacttgt tacttcaact tccagagata aggatgcatc aattttacct
    86221 gattcataac atttttgaaa acgatccgaa gtccaaccaa acatcattgc aaacaataac
    86281 tttaataaaa tatgatgtcg atagcaatcc gcttcagaaa cttctcgctt acctctaact
    86341 ccaatcgcta gtttgggaga agatacttcc attctcatac tatctgttgg ctttacaggc
    86401 tgtaaaaaca acttttctct tgctacttcc tgaaaatctg aatctttcag ttctttgctt
    86461 tcaaaatagt cctgtactcg ctccacatca aaattaccaa ctaaaaacag agacatgttt
    86521 acaggtttgt aaaactttgt aaaattttct tgcaaattag ttagattgat ttgggaaatg
    86581 gactcctcac ttccaactat atcagttgct aaaggtgtac caggatacaa attcgctaaa
    86641 gttgaaaaga ataaacacga atctggatca tcttggtaca tttctcgttc ttgctgaata
    86701 atatcctgct ctgtcagaat ggaagcttca gtaaagtgtg ctgatgttac caattcatca
    86761 agtaaatcta aattttctaa aaaataatcc gttgctgaaa aaagatagtt tgtttttgta
    86821 aagcttgtaa aggcattact atctgcacct agactcgtaa aagccgacat caaatcacta
    86881 gaatcttctc tctcaaataa tttatgttca agaaaatgag caattcctcc aggatattgt
    86941 tttacatctc cgtcaacttc tgtgacaaac gtatctaccg aaccaaactg tacagtgaca
    87001 ctcccgtaaa cctctttaaa ttccttttta ggcaaaagag caactatcaa tccattggcc
    87061 aaacgagttc gataaacctt ttcttttaca gctggatagt atttttcttc aaaaacaacc
    87121 tttgtcattc tattccttcc ataaagtaaa tcgcttgtag tttcacatta ttagctactc
    87181 tacaaatagc atctttgtca atctgttcaa gctttacaat ccaactttta aagtctgctg
    87241 aagattttcc aaataaggca ttttgataag cacgttcaat caatgaagat tgattatctt
    87301 gagaaagtaa caacgaccaa cgaatcattt ccttggtctg atttaactca aactctgtaa
    87361 aataaccttt ttttaaatca agcagttgat tattcatcat tttacgagcc tggttacgat
    87421 tttctcgatt gataccagca tacatcctca agaatccact aaataaatca agctcacttg
    87481 aaatggtata agctaatcca gcattttcac ggacatttgt aaagagctta gaatgagcaa
    87541 atccaccaag taaaccattc attacaatca tgggtaaatg ttgctcatca ccatatttag
    87601 aacggtaatg ataacctaat tccaaaatgg attgtcccac atttttccga accatacctt
    87661 cctgaaggat attagaataa ggttgacaat actgaacctt cacatctcct tttcgacctt
    87721 taaagccaaa tgattctaat acattttgaa tttcaacctc attaaaatca cctaggaaaa
    87781 agaaatctat tcgatcattg gctaaaaatt cttggaaaca agaataagaa ctttgtggag
    87841 tttcagctaa aatacgattt cgtaaatcac tatattccaa ttgaagacgt tcatcatgaa
    87901 aaaacaattt atccaattct ttatgtgcaa aataaaaaga atcatccata tcagctgcta
    87961 aacttgctag caattgtttt ttctcaattt caaataaggc cggatcaaac ccattatcaa
    88021 ctactacggg tgaaaaaaga gtttctttta caagttccaa aatctgagag gttagcacgt
    88081 ttttcctact taaaaactca tcacgaacat aggtaaatgt caattctata atgtggcttt
    88141 gccctcttct gaaacaattg gttgacatat ctgtaccgta tagactggcc aagtgtctcc
    88201 tcaaatcttg agaagtgggg tacatctgat tagcagtctc tagcatactt gcactcaaca
    88261 tgtgacctgc aatcgtatca agggataatg gagcggtaaa acgcacggta attttgtgtg
    88321 ttttaaactt ttttgattgg ataaaatgtg ttgaaattcc atgcactaac tccatgattt
    88381 acctccttat atacagactt ctattatatc acgaaaacct gaaattttct tattccctgt
    88441 aacacttttg aaataaaaat cgcttacatt tctctctgtc tctctcacta tttttaggaa
    88501 aatatggtat aataccaaag attgaggtga attatggaat acaaattatt tgaagaattt
    88561 attaccctcc aagcactact caaagaactt ggaattacac atagcggagg agctattaaa
    88621 tcatttctct ctgaacattc tgtttacttt aatagggaat tagagagtcg tcgtggaaaa
    88681 aaacttcgta ttggcgataa agttgacatc cctgacatga acattgacat cttgttgaca
    88741 caacctactt ctgaagaaca agatgaatac caagctgata aagttgaaaa agaacggatc
    88801 gctaaacttg tcaaaaagat gaataaggga gttaaaaaag acaaatcgaa acctgcttca
    88861 tcacctaaaa gccaacaagc tccacgattc cctggtagat aatcatgtgg ctacaacatc
    88921 tatctctcaa gacttttcgt aattacaaag aaacgaaaat agactttaat cctaaattga
    88981 atgtcttttt gggacgtaat gcacaaggaa aaacaaacat gttagaggct atctattttt
    89041 tagccttaac gcgtagtcat cgaactcgaa cagataaaaa tctcattcat tttgatgagg
    89101 aacaacttca tctttcaggt ctcgttcaga aaaaaactgg atccattccc ctagaaatcg
    89161 aactaacaca aaaaggccgt gtaacaaaag ttaatcactt aaaacaggca cgcctttcag
    89221 attatgtagg acacatgaat gttgtcttat ttgctcctga agatttacaa ctaattaaag
    89281 gagcaccttc gattcgacga aaattcattg atatggaact tgggcaaatt aagccaatct
    89341 acttatctga cttaaccaat tataaccaca tcctaaagca aagaaacact tacctaaaat
    89401 cagatcaaaa aatagatgaa acattccttt ctgtgttaga tgatcagcta gttgattatg
    89461 gatgtcgtgt aatgaatcac cgcttaaatt tcataaaaaa actagaatca tttgggcgta
    89521 agaaacattt tgaactctct aatcagatcg aagagttgtc aatatcctat caatcttctg
    89581 tcaatataac tgacaaacaa aacttatccg aatctttcaa aattgcttta gaaaaaagta
    89641 aatccagaga tttatttaaa aagaatactg gtgtcggtcc tcatcgagat gacatttctt
    89701 tttatataaa tgggatggat gctagtttcg gaagccaagg tcaacatcgt agtctcgtcc
    89761 tctcgataaa attagcagaa atcgaattaa tggaaagcat taccacagaa tctccgatat
    89821 tactgcttga cgatgtgatg agtgaacttg acaacactag acagttaaaa ttattagaaa
    89881 cgatttctca atcaatccaa acctttatca caacaacaag cttagaccat cttcaaaatc
    89941 tgccagaaaa tctaagtatc ttcactattc aggatggtaa agctgctgta aatggaaatt
    90001 gacaacatta taaaagaact cctgttttca ctggagttct tttcattgtt ttttacatag
    90061 aataatttgg tgcctcatta gtaatttgca catcatgagg atggctttct ttcaaaccag
    90121 caccagacat ttcaataaat tgagcattat cgtgtagttc tttaaggtta gctgcaccac
    90181 agtaacccat accagagcga ataccaccaa tcatttggaa aacaatatca gctgccgctc
    90241 ctttataagc aacacgacct tcaattcctt ctggaacaag cttgtttgct tcattgacag
    90301 aaccttggaa ataacggtcg cttgaacctt tcttcatagc agcaattgat cccataccac
    90361 ggtaagtctt gaatttacgt ccttggaaga tttcagtttc gcctggagct tcatcagttc
    90421 cagcaaacat agatccaagc ataacagcat ttccacctgc agcaagtgct tttacaatat
    90481 ctccagaata cttgatccca ccgtcagcaa taatcgtttt accatattcg cgcgcaacag
    90541 ctgcagcatc gtagatagct gttacttgcg gaacaccaac accagcaatc acacgagtag
    90601 tacagataga acctggtcca ataccaacct taacaacgtc tacacccgct tcataaaggg
    90661 cacgtgcacc ttcagcagta gcaatatttc cagcaatcaa agtccgatct gggaaatgag
    90721 cacgaatctc ggcaatttta cgcaagacac ctgcagaatg accatgtgca gtatcaataa
    90781 caatcgcatc cgctcctgcc tcaaaaagag cctctgcacg ttcaaatgta tctgaagtaa
    90841 cacctactgc acctgcaact agaagacgac caaactcatc tttagccgca tttggaaact
    90901 caataacttt ttcaatatct ttgatagtga tcaaaccaga aagactgcct tcttcatcga
    90961 ccaacggaag tttttcaata cgatgctctt gaagaatact ctcagccgtt gcaagatccg
    91021 tacccacagg agcagtaaca agattttcac tagtcatatg gtttgaaatt ggttgattat
    91081 aatctgaaat aaaacgaaga tctcggtttg tcaaaatacc aaccaattta cgattttcaa
    91141 gtgtttcaac aactggaaca ccactgatgc ggtaacgacc cataagctca tctgcttcag
    91201 caattgtatg ttcaggcgtc aagaagaacg gatcaataat aactccattt tcagaacgtt
    91261 ttaccttacg aacctcgtct gcttgttgag caattgacat gtttttatgg ataactccga
    91321 gaccacctgc acgagcaata gcaatggcca tttgactctc tgtaactgtg tccatggcag
    91381 cggtaataat tgggatattt aaagtcaaat tatctgccaa tttagttgtt aaatctgcat
    91441 cgttaggcaa cacatgactt tcagctggaa taagcaatac atcatcaaag gtaaaacctt
    91501 ttttcaaaaa tttagtgtcc caattagaca ttcgaagttt cctcttttct ttctttttga
    91561 gcttgactct ttttatattg tatctatcat accattctat acaaatttgt caaatgttac
    91621 aggggtaaat aaaaaactat cttttcttcg agatagaaat gatagtttct tgtaaaataa
    91681 acttagttaa agtaatgaag tcccattgcc ccttttacct cagatagggt ttgacccgca
    91741 acttcacgcg ctctttcact acctttttga atcatattat aaacttctcc catatcctta
    91801 gcaaattcaa tacggcgctc acgaatagga cccagttcac gttctaatat ttcaagtaga
    91861 taacgcttgg tcttcacatc accaagacca cctcgttgat aacgttcttt catatcagca
    91921 atttcttgag catcttctgg acgaccaaaa acatctagat aatggaaaac catatttccc
    91981 tcaatcttac ctggatcctc aacgcggata tgatctggat ctgtatacat actcattact
    92041 tttttacgca aagtatccgc atcatcagct aaataaatac cattatttag tgatttagac
    92101 attttagcat ttccatctaa accaggcaaa cgccctgctc tctcattttc tggataaata
    92161 ccttccggct ctaccaagac atcacagtta tatgcattgt taaaagaacg aacaatttca
    92221 cgagtttgct caatcattgg tttctgatct gtcccaacag gaacataatt agccttgaaa
    92281 gctgtgatat cagctgcttg agcgattgga tagaccaaga atcctgtcgg aatgctttct
    92341 ccaaatcctt tctgagaaat ctctgtcttg actgttggat ttcgctccaa acgtgctaac
    92401 gaaactagat tcatataata catagacaac tcagccaact ctggaatctg gctttgaata
    92461 aaaatagttg acttatttgg atccaatcca actgcaagat aatccaaagc cacatttccg
    92521 atagactcta caatggtttg aggatctttg gcatgatctg tcaaggcttg ttggtcagcc
    92581 aagaacacaa acatatcata cttatcctct tcctgtaata atactcgatt tttgagactt
    92641 ccaacataat gtccaatatg caattttcct gttggacggt ctcctgttaa aataatgggt
    92701 ttagtcattt tgttctcctt cgatatagtc ctttcaatta tagcattttt ttaatgaaat
    92761 aaccgtaatt tatcaaaata aatcagcctt gctttttaca gatttgtgta aaggatactg
    92821 taaatataat ttacacaaaa ttgacaaata aaaatttgaa tatttctgta ttttctagta
    92881 gaataaatat attacacata taggagaaaa atattgctta cagtatctga tgtttcacta
    92941 cgttttagtg atcgcaaact ttttgatgat gtcaatatca aatttacaga aggaaatact
    93001 tacggattaa tcggtgctaa tggtgccgga aaatcaacct ttttaaaaat tttagctgga
    93061 gatatcgaac ctactactgg tcacatctct cttggtccag atgaacgtct ctctgttctt
    93121 cgtcaaaatc actttgacta cgaagatgaa cgtgccattg atgtcgttat catgggaaat
    93181 gaaaaacttt atagcatcat gaaagagaaa gatgctatct acatgaagga agatttctca
    93241 gacgaggacg gggttcgtgc tgccgaactc gaaggagagt ttgccgaact tggaggttgg
    93301 gaagcagaga gtgaagcctc tcaactactt caaaacctaa acattccaga agaattacac
    93361 taccaaaaca tgagcgaatt ggccaacggt gaaaaagtaa aggttctcct cgccaaagca
    93421 ctttttggta aaccagatgt tcttctcttg gacgagccta ctaacggttt ggatatccaa
    93481 tcgattactt ggttagaaga cttcttaatt gactttgata acacagttat cgtagtatcc
    93541 cacgaccgtc acttcttaaa caaagtttgt actcacatgg ccgaccttga ctttggaaaa
    93601 atcaaactct atgtcggaaa ctacgacttc tggaaggaat cttctgagct tgctgctaaa
    93661 ttgctagcag accgtaatgc taaagcagaa gaaaaaatta aacaattgca agaattcgtt
    93721 gctcgtttct ctgccaatgc ttctaagtca aggcaggcaa catcacgtaa gaaaatgctt
    93781 gataagattg agctagaaga gattgtgcca tctagtcgta aatatccatt tatcaacttt
    93841 aaagcggaac gtgagattgg taatgatctc ttgacagtag aaaatctaac tgtaaagatt
    93901 gatggtgaaa ctatcttgga taatattagt ttcatcttgc gtccagatga taagacagca
    93961 cttattggac aaaatgatat tcaaacgact gcattaattc gtgcaatcat gggagatatt
    94021 gactatgaag gaactgtcaa gtggggagtt acaactagtc aatcttacct accaaaagat
    94081 aactcagctg attttgcagg aggagaatca attcttgact ggttgcgtca attcgcaagt
    94141 aaagaagaag atgacaatac tttcctacgt ggcttcctcg gccgtatgct cttctctgga
    94201 gatgaagtta acaaacctgt aaatgtcttg tcagggggag aaaaagttcg tgtcatgctt
    94261 tcaaaactca tgctcttaaa atcaaatgtc cttgtacttg atgatccaac aaatcacttg
    94321 gacttggaat ctatctcaag cttgaatgat ggattgaaaa actttaaaga atcaatcatc
    94381 tttgctagcc atgaccacga atttattcaa actttggcta accatatcat tgtcttatct
    94441 aaaaatggcg tcattgaccg tatcgatgaa acctacgatg aattcctaga aaatgcagaa
    94501 gtacaagcaa aagttaaaga actttggaaa gactaaataa aacttcaaaa ctcagttggg
    94561 ttaaccaact gagttttcta tcattctacg aggtaacatg aaatcatttt taaaaacata
    94621 tcgaacctat tttatttctt tcatcattcc tgtagtgatt atgtctggag tatatctatc
    94681 tcaaggtatc tactggaata gcgacaactc tcctctatta ggagatggct ttcatcaata
    94741 cgttattttt gatgtagcct tacgaaatat cctacatgga aatagtagtc tgttttacac
    94801 ctttacaagt ggtctagggc taaacttcta tgccctatct agttattact tgggtagttt
    94861 tctcgcgcct ctagtttact tttttgatct aacgaatatg ccagatgctg tctatctgac
    94921 cactctctta aaatttggat tgattggtct gtcaaccttt tttagtttga ataaattgtt
    94981 tcaatctatc cctcagactt taaaactagc cttatctact tcctatgctc tgatgagttt
    95041 cactgtcagt caattagaga taaaaacctg gctagatgtt tttatcttga ttcctttaat
    95101 tataactggt ttacatctac tgataactga aaagaaactc ctattgtact ttacaagtct
    95161 gtcaatctta tttattcaaa attattattt tggatatatg acagtattgt ttcttatttt
    95221 ctggtatctc tgtcaaattt cgtgggactt taagactcga aaatcatctg ttcttgattt
    95281 catagttatc tcctttttag ctggtatggc tagtttgatt atgactcttc ccactctatt
    95341 tgatttacag acacatgggg aaaaattgac tgaagttaca aagtttcaaa ctgaaagtag
    95401 ctggtatctt gatctctttg ctaagcaatt cattggttcc tttgacacaa caaagtatgg
    95461 ggccatccca atgatttttg ttggactatt tccctttatt ttgaccattt tattttttac
    95521 gctgaaatct attaagtttc acgtgaaact catatatgta atattctttg catttctaat
    95581 tgcaagcttt tacatagaag ctcttgactt attttggcaa ggcatgcata ctccaaacat
    95641 gtttttacat cgctatgctt ggattttctc taccttgtta atttacacag cagcagaagt
    95701 cttaaagcgt ctgaaagaac ttaaagtctg gaatttttta gtttcgcttt ttcttgtagt
    95761 agcaggattt ttagctacca tctatctaaa atcgcattat tcttttttaa cagatttgaa
    95821 tattctgctt actcttgaat ttttggttgt ctattctctt ttactccttg cagttatcaa
    95881 aaagtttata tctgtgaatc tatttgccat tctaatctct ttatttatac tggttgaaat
    95941 gagtttaaat gcttcatctc aaatggacgg aattgctaag gaatggggat ttgcttctcg
    96001 aagtgcttat agtcgagata tcccagctat ggaatctttc tcaacatata ttggaaatca
    96061 atttactcgt actgaaaaac tacaaactca gacaggaaat gacagtatga aattcaacta
    96121 caatggaatc tctcaatttt catctgttcg aaatcgttca tcaagctcta ctttagataa
    96181 acttggtttt aaatcctctg ggactaatct caatctccga tatgcaaata atagtatttt
    96241 ggctgatagt ttatttggta tccagtacaa tatctcagac agtcctattg ataagtatgg
    96301 ctttaaagat atctatcaaa aagataatct taccctatat gaaaatcaat actctcttcc
    96361 gattgcagtt gctagtcaat ctgtttacaa tgatgtcaag ttcaatgaac ataccttgga
    96421 taatcaggcc tcatttttaa atcaacttgc taacgtcaat tttgattatt tttctccaat
    96481 accttatgaa aaaacagaaa aaatagaaaa tactaatgat ttgattagtg tcacaagttc
    96541 ttcaaatgaa gatgcagcaa tccagtatca aattgaagtt ccagaaaaca gccaagttta
    96601 tctctctttc ataaaccttc acttttctaa cgataaacaa aagaaggttg acatacttgt
    96661 aaatggtgaa aaaaagactt ttacaactga taatgtcttc tccttcttta atctaggata
    96721 tactaaagag aaaaaaactt tcaatatcaa tgttagtttc cctggaaatt cacaagtatc
    96781 atttgaatct cctaccttct atcgtttaga taccaaaact ttcaccgagg caattcaaaa
    96841 aattaaagaa caacctgtca cagtatcaac ttctaaaaac aaggtttttg ctacatatga
    96901 tgtccaacaa gatacatcta ttttcttcac cattccttat gacaaaggtt ggtctgccta
    96961 ccaagatggt aagaaaatag aaattaaaca agctcaaact ggatttatga aagttgacat
    97021 tcccaagggg aaaggaacta ttacactttc cttcattccc aatggtttta ttactggagc
    97081 aatctgttcc tttacttctc tcttactatt tggaatctat aatcacagac gaaagtcatc
    97141 taaggcataa aaaatcgacc agttaatcgg tcgatttttt taatcttctt ccattttctt
    97201 atgttgatag gctagcatac ctaaaccagt aaatagagct agtatgacag ctaggaaaat
    97261 gacttgttga tagagattgt ttgtcgtaat cccgaaactg aatagctcat tggtaaccag
    97321 ggattaatag atctaaagaa atcatttgtc aaagcaagtg gataagtacc tgcacttgat
    97381 gctaactgta gtaaaagcaa aataagtgag aaaaaagctc ctatacggct attccacgtt
    97441 gctaaagtgg tcaccataga catgaatact aaacttgtta ggatgatgag aataaatatt
    97501 ctcatctcat gattagcagt taaaccaata agctgaactc ctccatatac caaaattcct
    97561 gccaaaacag ctataatacc atttatttca gctcaagatt tcaaccaagc ccaacggctc
    97621 tctggatgac gtcctgaagg caatttcgca aatatcatat ttgttgatat tgctgcaaaa
    97681 aaaagagcaa ctgatatcat ataaggagct attgcgattc catttacagg aacttgatca
    97741 ttgtctgttt ttgaaagatt gagtggattt gacaaaatct ctgcattttt agattctgtt
    97801 gatactgatt tgagttgatc actagcatta cctagtcctt gtcctaaaga agcaagtcct
    97861 gtctgtaaat cttccaatcc agaagttaac tttgttccac cttctgctag tttcccagat
    97921 ccatctgcca atttattagc tctattctct aatggagaag cacctgaaag taactgactg
    97981 gatttgtctg ctaattgccc agatcctgat tgtaattaac caactcctgc tgtcaatcta
    98041 gaagattttt gtgtcaaggt gtttgagcct gaaactagtt tatccaaact acctgtcaag
    98101 gtggcatttt tttcacttag ttgacttgcg ccctgagaaa ctttatcaac acctgtagta
    98161 tatgcgttta cacctgatgc aatcaactga ctggcaggaa ctaatttgct agtaacagct
    98221 ccttgtatct ctgttaatcc acttgacaat cctatcaaag aagtagaagt aataggtaat
    98281 acttgattag cttgattttt taaagtcgaa agattagaag attgattttg taagttttct
    98341 aaacttccct gtaaaccttg tactaaagct acaattgact gagccgattg aatactatca
    98401 gttgaatttt gagatacaga atcacttatc ccagtttgtt gctcacttgt caatgattga
    98461 taagctgctg tcgattgaat attggataat gtagttgttt ttttagataa atcacttggt
    98521 aaagtcacta ccatatagta atcgccatct tccaatccct tctttccttc ctcttcatct
    98581 acaaaatgaa aatccaaggt tttattttct tttaaattgg acaccatgtc ttttcctatt
    98641 gccatagtat taccattata ggaagcctct ttatcattat ttacaactgc cacaggtaag
    98701 tcagacaatt gcccatatgg atcccacatt gatgacaaaa atatgatatt gtacagagct
    98761 ggaataagag aaatcccgat catgacaata ataaaggttg ttttttttaa attgctttcc
    98821 attctttaaa catagtttct ccttttttaa acatattgtc taaaattttg atataataga
    98881 ttatacatta aaaaatctaa attacaagat aaaaaatcta tttttagaca tatagtctaa
    98941 tttgtttaca aggaggaaat atgcaagaaa gtaacaaacg cttaaaaaca aagcgaacta
    99001 ttgaaaatgc tatggtacaa ttactgatgg aacagccatt tgataaaatt tctactgtca
    99061 aattagtaga aaaagccgga attagtcgtt ccagcttcta tactcactat aaggataagt
    99121 atgatatgat tgagcactat caaagcaagc tattccatac atttgaatat atttttcaaa
    99181 aacatgctca tcacaaaaga gacgctattt tagaagtttt tgaatatcta gagtcagaac
    99241 cacttctggc tgcccttctt tctgaaaatg ggactaaaga aatccaaaat ttcttacgaa
    99301 ataaacttca tatcatgctt agtacagatt tacaaaagcg atttatgcaa ctgaatctaa
    99361 ataccactga attagaatat agtagcatct atctaactca tgcacttttt ggtgtctgcc
    99421 aaacttggat tgcacatgga aaaaaagaaa gttctcaaga aataacagac ttccttatga
    99481 aaatgcttgg tgatacaaat tgatacaaaa agaggaacac agctgtgttc ccttttatct
    99541 atactccgcc agtaggactc gaacctacga catcatgatt aacagtcatg cgctactacc
    99601 aactgagcta tggcggataa aatagtccgt acgggattcg aacccgtgtt accgccgtga
    99661 aaaggcggtg tcttaacccc ttgaccaacg gaccttctat ctgtagcaga tataaccatt
    99721 atatcaattt cttgctaatt gtcaatcact tttgagattt tttctctaaa atatctttta
    99781 attttctaat ttttaatctt gaaataggac aacgatggtc ttcatagaaa acaatttcta
    99841 agttttttcg atcaatttct ctgatattgc ctatatttac caaaaatgac ttgtgaggag
    99901 aataaaatcg ctgagtatgt ttgtcctttt cctgaatatc tgtcatggta ccataaaact
    99961 cttttgcaaa attcttacca ataatgcgca atttatgaga tacccctgtt gtttcaatat
   100021 acaaaatatc atggtaagga atttttaaat catttccctt gtaattgtag tcgaaataat
   100081 ctacaacatc ttcattttca agtaacatac tcttcgtgta gaagatattt tgctcaattc
   100141 tcttcttaaa catctcatca ttgatatcct tatcaacaaa atctagggct gatacctggt
   100201 atttataggt tagagtcgca aactctgatc gactagtgat aaagacgata atagcgtaag
   100261 gattgtaatg acgaatgagc tgagccactt caaatccctt tttctcaatt ccatgaatat
   100321 cgatatctag gaaataaagc tgatttactt catcattttc aatgtattct tcaaattcac
   100381 ggacttttcc cgttgtcttg tatgatattg gaatattcga ttctttcgaa atttcatcca
   100441 atattctctc tagtctcact tgatgttcaa taacatcttc taaaattaaa actttcattc
   100501 aaattccctc ttaaatctaa tgatttgtct aaatgtactg ccttccatct ctgtttctaa
   100561 aataatattg ttgtacttat ctagtagttc tttcacatta tttaatccga ctccgcgatt
   100621 tcttccctta gtggagaatc ctaaggcaaa tagatctcct gaaggagtca tcgtcatttt
   100681 acatgaattc tgaatcacaa taactgtttc agtttccatc ttaataactg ctacttccat
   100741 ctgcttttta tagctatcag ccgatccttc gacagcatta ttcaataaaa cgctcatgat
   100801 acgaaccaaa tccaatagtt caattggaag cttggtaatc gtatctttta cttccagtgt
   100861 aaactctaca ccattatttc gagcatagac aattgactga gcaaccaaac ttcgtaaagc
   100921 tgagtcttct atgttgttca aatcaaagta agtgtactta tctgaacgca atttatgatt
   100981 tgctttgact aaaacttcat tgtaaattct gtcaatttcc tgtaaattac cactgtcaat
   101041 tgccatctgc atgctgacaa gcattccagc ataatcatgt cgaaaaccac ggatttcatt
   101101 atacagacca acaatttcat ctgtgtaatt ctgtaaatgt ttctgttcaa atttcttctg
   101161 cttcaaagca atctctttct ccatttgaac tttatgagaa ttcattgcaa agaaggtcaa
   101221 aaggagagag ataaagacaa tagatgacaa aatacttcca aaactattca aatgtttaat
   101281 cgtacttacc atatctgaaa cgaaagatac aatatgtagc aatagtaaag caaaaaatac
   101341 ttttttcaag aaaggataaa ggtagtcctc gtcaaaatag gctagttcca aatggaaata
   101401 gtaaatgatt tttaatgtaa caaaataggt taacaccgtc acaacgaaaa agaatgggaa
   101461 atgatattgt aaaacaaaat tatctcctgt tatagaggag aaagttacgg acagaaagtt
   101521 atgagtgctc tcatataaaa gagatagtag taaacttagg aatagtcctc tatccctctc
   101581 atactgtttc atccatcgaa aataggaata taatcccaaa ggaaataaaa atctttcaat
   101641 ccctaaccca tctaaatata gaatatataa gggaaaatca aatactattt ctgttagtaa
   101701 tgtataagca ccaaaaacga ataattcttt tctatttatt tgacctttac aaataaaatg
   101761 gtaactgtga ctaataatta aaaaatgaac aataaccgtc ccaaatccaa ataaatccat
   101821 tactctttcc ccttatttca ttactttttt ctttgtaaaa taaaatcacg gaagaatttt
   101881 gacaacctca tctccccacc tttaatcttt tgtaagtctt tttccttcaa agctacaaac
   101941 tgttccaatt taactgtgtt tttcataata aaatctccta aaatgttttt tcttgtaagc
   102001 taacttacaa aaaccattat acaaaatgga atttcgtttt agataaaatt ctctcaactg
   102061 tcattttttt ctcccaaagt gtactttttt aagaaaaaag ccgggaaaat tcccagcttt
   102121 gctattatat tgatcccagc aggattcgaa cctgcgaccg ttcgcttaga aggcgaatgc
   102181 tctatccagc tgagctatga gacctaatac aattattcta ccaaaaattc aattaaaagt
   102241 caattttcta tttatggtag gggaatccct gctgaatcgt aaaagcgcga tagatttgtt
   102301 caacaagaac tagtctcatt aactgatggg gtaaggttag gcgaccaaaa ctgacagaaa
   102361 gattggctct attttttaca gatgatgaca atcctaaact tcccccaata ataaaagtaa
   102421 gagtagaaaa tccttttata gaagtttctt ctaactgctt actaaattct tctgagaaga
   102481 aagttttccc ttcaatggct aacacaataa cgaaatcacg gtcagcaatt tttgataaaa
   102541 ttctctgacc ttctatttct aaaatctttt gattttctga ttcactggcc ttatctggtg
   102601 ttttttcatc tgataactca atcatttcaa acttagcaaa tctagaaatt cgttttgaat
   102661 actctgcgat accatctttt aaatactttt ctttcagttt cccaactgtt acaactttaa
   102721 ttttcatgac tctattctaa catattctct attttttcac atcttattca caaaataaaa
   102781 aatagatttc aatta
//
LOCUS       DAVMCN010000003        77568 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVMCN010000003 DAVMCN010000000
VERSION     DAVMCN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77568
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.003"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            89..1342
                     /locus_tag="VYP85_000261"
     CDS             89..1342
                     /locus_tag="VYP85_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1880827.1"
                     /translation="MVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRI
                     ISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLS
                     QLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAE
                     GIEGVAQSFESEHNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLL
                     SDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFP
                     KFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSN
                     FDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRL
                     IYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1704..2705
                     /locus_tag="VYP85_000262"
     CDS             1704..2705
                     /locus_tag="VYP85_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1880828.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            2854..3771
                     /locus_tag="VYP85_000263"
     CDS             2854..3771
                     /locus_tag="VYP85_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1880829.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYDYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            3782..4672
                     /locus_tag="VYP85_000264"
     CDS             3782..4672
                     /locus_tag="VYP85_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1880830.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4701..6317
                     /locus_tag="VYP85_000265"
     CDS             4701..6317
                     /locus_tag="VYP85_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1880831.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKATDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTIPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSNYLAIKQKYYDQYQANKN"
     gene            6327..7646
                     /locus_tag="VYP85_000266"
     CDS             6327..7646
                     /locus_tag="VYP85_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1880832.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(7854..7926)
                     /locus_tag="VYP85_000267"
     tRNA            complement(7854..7926)
                     /locus_tag="VYP85_000267"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7891..7893),aa:Lys,seq:ctt)
     gene            complement(8191..9462)
                     /locus_tag="VYP85_000268"
     CDS             complement(8191..9462)
                     /locus_tag="VYP85_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1880833.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPVELDEEALDFIATSTNGDLRSAFNSLDLAVLSTSENDKGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            9760..9975
                     /locus_tag="VYP85_000269"
     CDS             9760..9975
                     /locus_tag="VYP85_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880834.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10140..10319
                     /locus_tag="VYP85_000270"
     CDS             10140..10319
                     /locus_tag="VYP85_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880835.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10456..10635
                     /locus_tag="VYP85_000271"
     CDS             10456..10635
                     /locus_tag="VYP85_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1880836.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            10672..11124
                     /locus_tag="VYP85_000272"
     CDS             10672..11124
                     /locus_tag="VYP85_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1880837.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTISKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11415..11885
                     /locus_tag="VYP85_000273"
     CDS             11415..11885
                     /locus_tag="VYP85_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1880838.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEKGEFYPYPKY"
     gene            11904..12992
                     /locus_tag="VYP85_000274"
     CDS             11904..12992
                     /locus_tag="VYP85_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1880839.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKEMLEGTEDGTRNF"
     gene            12973..13401
                     /locus_tag="VYP85_000275"
     CDS             12973..13401
                     /locus_tag="VYP85_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1880840.1"
                     /translation="MELEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13537..14487
                     /locus_tag="VYP85_000276"
     CDS             13537..14487
                     /locus_tag="VYP85_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1880841.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            14489..15232
                     /locus_tag="VYP85_000277"
     CDS             14489..15232
                     /locus_tag="VYP85_000277"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1880842.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15243..17039
                     /gene="pepF"
                     /locus_tag="VYP85_000278"
     CDS             15243..17039
                     /gene="pepF"
                     /locus_tag="VYP85_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1880843.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17286..17840
                     /locus_tag="VYP85_000279"
     CDS             17286..17840
                     /locus_tag="VYP85_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1880844.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTDFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            17951..18619
                     /locus_tag="VYP85_000280"
     CDS             17951..18619
                     /locus_tag="VYP85_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1880845.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(18788..18877)
                     /locus_tag="VYP85_000281"
                     /pseudo
     CDS             complement(18788..18877)
                     /locus_tag="VYP85_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(18874..19407)
                     /gene="queF"
                     /locus_tag="VYP85_000282"
     CDS             complement(18874..19407)
                     /gene="queF"
                     /locus_tag="VYP85_000282"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1880846.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(19713..20027)
                     /gene="trxA"
                     /locus_tag="VYP85_000283"
     CDS             complement(19713..20027)
                     /gene="trxA"
                     /locus_tag="VYP85_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1880847.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20044..20265)
                     /locus_tag="VYP85_000284"
     CDS             complement(20044..20265)
                     /locus_tag="VYP85_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1880848.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20364..20744)
                     /locus_tag="VYP85_000285"
     CDS             complement(20364..20744)
                     /locus_tag="VYP85_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1880849.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(20888..21841)
                     /locus_tag="VYP85_000286"
     CDS             complement(20888..21841)
                     /locus_tag="VYP85_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1880850.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREKKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIESYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(21909..23116)
                     /gene="sstT"
                     /locus_tag="VYP85_000287"
                     /pseudo
     CDS             complement(21909..23116)
                     /gene="sstT"
                     /locus_tag="VYP85_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23255..23815
                     /locus_tag="VYP85_000288"
     CDS             23255..23815
                     /locus_tag="VYP85_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1880851.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23872..24780
                     /locus_tag="VYP85_000289"
     CDS             23872..24780
                     /locus_tag="VYP85_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1880852.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            24732..25322
                     /locus_tag="VYP85_000290"
     CDS             24732..25322
                     /locus_tag="VYP85_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1880853.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25325..26431
                     /gene="yqeH"
                     /locus_tag="VYP85_000291"
     CDS             25325..26431
                     /gene="yqeH"
                     /locus_tag="VYP85_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1880854.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            26646..26957
                     /gene="yhbY"
                     /locus_tag="VYP85_000292"
     CDS             26646..26957
                     /gene="yhbY"
                     /locus_tag="VYP85_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1880855.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27009..27638
                     /locus_tag="VYP85_000293"
     CDS             27009..27638
                     /locus_tag="VYP85_000293"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1880856.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            27638..28231
                     /gene="yqeK"
                     /locus_tag="VYP85_000294"
     CDS             27638..28231
                     /gene="yqeK"
                     /locus_tag="VYP85_000294"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1880857.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            28232..28732
                     /locus_tag="VYP85_000295"
     CDS             28232..28732
                     /locus_tag="VYP85_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1880858.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            28745..29098
                     /gene="rsfS"
                     /locus_tag="VYP85_000296"
     CDS             28745..29098
                     /gene="rsfS"
                     /locus_tag="VYP85_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1880859.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29201..29947
                     /locus_tag="VYP85_000297"
     CDS             29201..29947
                     /locus_tag="VYP85_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1880860.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            29957..31054
                     /locus_tag="VYP85_000298"
     CDS             29957..31054
                     /locus_tag="VYP85_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1880861.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHTIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            31292..31546
                     /locus_tag="VYP85_000299"
     CDS             31292..31546
                     /locus_tag="VYP85_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1880862.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
     gene            31550..31804
                     /locus_tag="VYP85_000300"
     CDS             31550..31804
                     /locus_tag="VYP85_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV1880863.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            31995..33608
                     /locus_tag="VYP85_000301"
     CDS             31995..33608
                     /locus_tag="VYP85_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1880864.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            33738..34364
                     /gene="gmk"
                     /locus_tag="VYP85_000302"
     CDS             33738..34364
                     /gene="gmk"
                     /locus_tag="VYP85_000302"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1880865.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQERLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            34389..34703
                     /locus_tag="VYP85_000303"
     CDS             34389..34703
                     /locus_tag="VYP85_000303"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1880866.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            34769..37165
                     /locus_tag="VYP85_000304"
     CDS             34769..37165
                     /locus_tag="VYP85_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1880867.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMERDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQMVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37178..38113
                     /locus_tag="VYP85_000305"
     CDS             37178..38113
                     /locus_tag="VYP85_000305"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1880868.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            38106..39419
                     /gene="rsmB"
                     /locus_tag="VYP85_000306"
     CDS             38106..39419
                     /gene="rsmB"
                     /locus_tag="VYP85_000306"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1880869.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVLLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            39434..40174
                     /locus_tag="VYP85_000307"
     CDS             39434..40174
                     /locus_tag="VYP85_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1880870.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            40171..42150
                     /gene="pknB"
                     /locus_tag="VYP85_000308"
     CDS             40171..42150
                     /gene="pknB"
                     /locus_tag="VYP85_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1880871.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENSSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYALSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            42265..43023
                     /locus_tag="VYP85_000309"
     CDS             42265..43023
                     /locus_tag="VYP85_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1880872.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            43025..43474
                     /locus_tag="VYP85_000310"
     CDS             43025..43474
                     /locus_tag="VYP85_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1880873.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            43536..44161
                     /locus_tag="VYP85_000311"
                     /pseudo
     CDS             43536..44161
                     /locus_tag="VYP85_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            44229..44477
                     /locus_tag="VYP85_000312"
     CDS             44229..44477
                     /locus_tag="VYP85_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880874.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMVRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            44608..45780
                     /locus_tag="VYP85_000313"
     CDS             44608..45780
                     /locus_tag="VYP85_000313"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1880875.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            45780..47054
                     /locus_tag="VYP85_000314"
     CDS             45780..47054
                     /locus_tag="VYP85_000314"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1880876.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(47090..48055)
                     /locus_tag="VYP85_000315"
     CDS             complement(47090..48055)
                     /locus_tag="VYP85_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1880877.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKKLKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(48036..49490)
                     /locus_tag="VYP85_000316"
     CDS             complement(48036..49490)
                     /locus_tag="VYP85_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1880878.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            49866..51803
                     /locus_tag="VYP85_000317"
     CDS             49866..51803
                     /locus_tag="VYP85_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEV1880879.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLVGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGNAVIEVKI"
     gene            51952..52839
                     /locus_tag="VYP85_000318"
     CDS             51952..52839
                     /locus_tag="VYP85_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1880880.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53159..53776)
                     /locus_tag="VYP85_000319"
     CDS             complement(53159..53776)
                     /locus_tag="VYP85_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1880881.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54191..54379)
                     /locus_tag="VYP85_000320"
                     /pseudo
     CDS             complement(54191..54379)
                     /locus_tag="VYP85_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(54889..54969)
                     /locus_tag="VYP85_000321"
                     /pseudo
     CDS             complement(54889..54969)
                     /locus_tag="VYP85_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            55086..55979
                     /locus_tag="VYP85_000322"
     CDS             55086..55979
                     /locus_tag="VYP85_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1880882.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            55976..57175
                     /locus_tag="VYP85_000323"
     CDS             55976..57175
                     /locus_tag="VYP85_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1880883.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVEVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(57528..58295)
                     /locus_tag="VYP85_000324"
     CDS             complement(57528..58295)
                     /locus_tag="VYP85_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880884.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(58312..59007)
                     /locus_tag="VYP85_000325"
     CDS             complement(58312..59007)
                     /locus_tag="VYP85_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1880885.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(59012..59377)
                     /locus_tag="VYP85_000326"
     CDS             complement(59012..59377)
                     /locus_tag="VYP85_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1880886.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            59517..59990
                     /gene="nrdR"
                     /locus_tag="VYP85_000327"
     CDS             59517..59990
                     /gene="nrdR"
                     /locus_tag="VYP85_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1880887.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            59991..61160
                     /locus_tag="VYP85_000328"
     CDS             59991..61160
                     /locus_tag="VYP85_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1880888.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            61161..62057
                     /gene="dnaI"
                     /locus_tag="VYP85_000329"
     CDS             61161..62057
                     /gene="dnaI"
                     /locus_tag="VYP85_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1880889.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            62054..62767
                     /locus_tag="VYP85_000330"
     CDS             62054..62767
                     /locus_tag="VYP85_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1880890.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKLRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            62781..64091
                     /gene="der"
                     /locus_tag="VYP85_000331"
     CDS             62781..64091
                     /gene="der"
                     /locus_tag="VYP85_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1880891.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            64182..64517
                     /locus_tag="VYP85_000332"
     CDS             64182..64517
                     /locus_tag="VYP85_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880892.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            64657..64992
                     /locus_tag="VYP85_000333"
     CDS             64657..64992
                     /locus_tag="VYP85_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880893.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVRH"
     gene            65177..65968
                     /locus_tag="VYP85_000334"
     CDS             65177..65968
                     /locus_tag="VYP85_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880894.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            65961..66602
                     /locus_tag="VYP85_000335"
     CDS             65961..66602
                     /locus_tag="VYP85_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880895.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLILSRLEEKFKKG"
     gene            66606..67256
                     /locus_tag="VYP85_000336"
     CDS             66606..67256
                     /locus_tag="VYP85_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1880896.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            67267..67554
                     /locus_tag="VYP85_000337"
     CDS             67267..67554
                     /locus_tag="VYP85_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880897.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            67700..70213
                     /gene="secA"
                     /locus_tag="VYP85_000338"
     CDS             67700..70213
                     /gene="secA"
                     /locus_tag="VYP85_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1880898.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            70294..71325
                     /locus_tag="VYP85_000339"
     CDS             70294..71325
                     /locus_tag="VYP85_000339"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1880899.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQALINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            71327..72358
                     /locus_tag="VYP85_000340"
     CDS             71327..72358
                     /locus_tag="VYP85_000340"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1880900.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            72397..72765
                     /locus_tag="VYP85_000341"
     CDS             72397..72765
                     /locus_tag="VYP85_000341"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1880901.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSRAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            72755..73858
                     /locus_tag="VYP85_000342"
     CDS             72755..73858
                     /locus_tag="VYP85_000342"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1880902.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            73877..75892
                     /gene="recG"
                     /locus_tag="VYP85_000343"
     CDS             73877..75892
                     /gene="recG"
                     /locus_tag="VYP85_000343"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1880903.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERETDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMIETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEVWQEDPEWRMIALHLEKKEHLD"
     gene            76208..77188
                     /locus_tag="VYP85_000344"
     CDS             76208..77188
                     /locus_tag="VYP85_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1880904.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        23186 a        14539 c        17461 g        22382 t
ORIGIN      
        1 ccatgttaaa tctgcttttc ctgacttgat ttttcattct tctactaatg gtatacgcat
       61 tattaatacc gatgatagtg atattgaaat ggtttaccat catttcttta aacattcaac
      121 tcatttttcg attttagaat tcatcttctt taatgaaggt tgtcaagctg agagtatttg
      181 taaagaattt tatatcagtt catcttcgct ctatcgtatt attagccaaa tcaataaagt
      241 gattaaaagg caatttcaat ttgaagtcag tctgacccct gttcaaatca ttggaaatga
      301 gagagacatt cgttactttt ttgcacaata tttttcagaa aaatattatt tcctagaatg
      361 gccatttgaa aatttttcat cagagccact atctcaattg ttagaattgg tttataagga
      421 aacaagcttt ccaatgaatt tgtcaacgca tagaatgcta aagttgctcc tagttacgaa
      481 cctatataga ataaagtttg gtcattttat ggaagtagat aaagattctt ttaacgacca
      541 aagtttggat tttttaatgc aggcagaagg aatagaaggt gttgctcaga gttttgaatc
      601 agaacacaat atctctttag atgaagaagt tgtttgccaa ttatttgtgt cttactttca
      661 aaaaatgttt ttcatagatg aaagtctctt tatgaaatgc gtaaaaaagg atagttatgt
      721 tgaaaaatct taccatctat tgagtgattt tattgatcag atttcagtca agtatcagat
      781 tgaaatggag aataaggata atctgatttg gcatctgcat aataccgcac atctgtatcg
      841 tcaagagttg tttactgagt ttattttatt tgatcaaaaa gggaatacaa tcaggaactt
      901 tcaaaatatt tttccaaaat ttgtttcaga tataaaaaaa gagctttctc actatttaga
      961 gactcttgag gtttgttcta gttcaatgat ggtaaatcat ctatcttata ccttcatcac
     1021 tcataccaaa catttggtga ttaatttgct acaaaatcag cctaaactaa aggttttggt
     1081 tatgagtaat tttgatcagt atcatgcaaa attcgttgca gagacacttt cttattactg
     1141 tagcaataat tttgaactgg aggtttggac cgaattagaa ttatcaaagg aatctttaga
     1201 agattcacct tatgatatta ttatttccaa ttttattatt cctcctattg aaaataagag
     1261 actcatctat tcaaataata taaacacggt ctcactcata tacttgttaa atgccatgat
     1321 gtttattcga ttagatgagt aaccaaaaat aacaaaaaaa cgctatttcg cgtttgaact
     1381 gtacctcaaa agttagacag aaaaagtcta atttttaggg tgtttttgtt aagaaaagac
     1441 cttcaatcat ttaagaaaaa tgtacatcta gatttatagc cctctaaaac tcttgctttt
     1501 tttgtagaag atacgaaaaa agccatgaaa ccaaggcttt tcctgtttta tgtagatgtt
     1561 tacacatgaa aattgaagta ttttcaaaag ctaattggag tgattttatt catgatggga
     1621 taaatgatct ggccaaaaat gattgagaaa tagttgctta aaaagcattt gcatgatact
     1681 atatattgaa aggaggtgat aatatggtag aacaaagaaa atcaattacc atgaaagatg
     1741 ttgctttaga agcaggagtt agtgttggaa ctgtttcacg tgtaattaat aaagaaaaag
     1801 gcattaaaga agtaactttg aaaaaagtgg aacaagcgat taaaactttg aattacattc
     1861 cagattacta cgctagagga atgaaaaaaa atcgaacaga aacgattgca atcattgtac
     1921 caagtatctg gcatcccttc ttttcagaat ttgctatgca tgtggaaaat gaagtctata
     1981 agagaaataa caaattactc ttatgttcta tcaatggtac aaatagagag caagactatc
     2041 tggagatgtt gcgtcataat aaagttgatg gagtggttgc cattacctat agtccaattg
     2101 aacattactt gacgtcagga attccctttg ttagtattga ccgcacatac tcagatattg
     2161 ccattccttg tgtttcatca gataatgatg caggtggaag agaagcagct aaacaattaa
     2221 ttagtaaagg atgtcagcat ttagcctttg tgggcggaca taatacaacc attaatgaaa
     2281 ccaaacgtcg tagaatttca tttgaaaagt atgtccaaga gcataaaata cctcttagta
     2341 tttttgattt ggatgagaca gttactgact attatggaaa gctagagagt ttcttggaag
     2401 aaaattcttc tatagatgga atttttacaa tcaacgattt tacagctttg gatgtgattg
     2461 aaatactaga aaaaaatggc aaacgtattc ctcatgatgt ccaaattatt ggatacgatg
     2521 gaattaaaat ggctggagat agagattatc tactttcaac tattgaacaa ccattggaag
     2581 aaatggcaaa agaagcggtt cgtattttgt ttgatataat tgatggaaag actgttaatt
     2641 tgcagacaat cctaccagta aaatttgttg aaggaaaaac aacaaaaaat gaaaataagt
     2701 cttgacagaa agcgctatca atgatagaat gaattcagat aaaaagattt atttttaaaa
     2761 caaaaatgaa acgtttcaaa aaaagaaata aagagacagc gccaagcgct atcttttcta
     2821 gaaaaaatga aacgtttcaa aaaggaagtt gctatgaata gcaaagcgaa gcaagtttct
     2881 ctttgggaaa gaatcaagaa acaaaaactc ttgttattga tgactgtccc tggtttagtt
     2941 ttaaccttta tctttaaata catccctatg tatggggttt taattgcatt taaagattac
     3001 aatcctttaa aaggaatttt agggagtgat tggattggtt tttctgagtt tacaaaattc
     3061 atatcctctc ccaactttgg tatcttgtta gccaacacat taaaattaag tatctatggt
     3121 ttattgcttg gctttttacc accaatcatt cttgctatta tgctcaatca actcttgagt
     3181 gaaaaagtca aaaaacgaat tcagctcatt ttatacgcac caaactttat ctcagtcgtt
     3241 gttattgtcg gtatgatttt cctcttcttt tcagtgggag gaccaatcaa caattttctt
     3301 tctatgtttg gaatgaaggc tgacttcttg acaaatccag acttctttag acctttatac
     3361 atctttagtg gtatctggca aggaatgggc tgggcttcaa cgctctacac ggcaacattg
     3421 gtaaatgtag atccagcctt agtagaagca gcccgactgg atggagccaa tatcttccaa
     3481 cgaatctggc acattgatat tccagctctt aagcctatta tggttatcca atttgtttta
     3541 gctgcaggtg gaattatgaa tgtcggatat gaaaaagcat tcttgatgca gacatcgtta
     3601 aatttgccaa cttctgaaat tatctcgaca tatgactata aagttggtct tgtatcagga
     3661 gactattctt actcaacagc ggttggtttg tttaatgcag tgattaacgt agtattgctt
     3721 gttgcagtta accaaatcgt taaacgcatg aataatggtg aaggaattta aggaggaaag
     3781 tatgaaaaat tcgattatgg atacaaaatt tgatagacgt atcttactct taaataaaat
     3841 cattattgtc tttatcgttt tgatgacttt gcttccttta ctttatatcg tcgtagcatc
     3901 ctttatggat cctaaggttc tggttagtag agggattagc tttaatccag ccgattggac
     3961 tgtagaaggt taccagcgtg tattcagtga ccaatctatt ctaagaggtt ttatcaattc
     4021 tctactatac tcttttggat ttgcagcttt aacagtcttg ctatctgtgt ttacagctta
     4081 tcctctttcc aaaaaagatt tggtagggcg ccgttggatt aactacttct tgattgtgac
     4141 tatgttcttt ggtggtggtt tagtcccaac ttacttgctc gtaaaagaat tgggaatgct
     4201 caatactcca tgggctatca ttgttccagg tgctgtcaac gtttggaata ttattcttgc
     4261 tagggcctat ttccaaggat tgcctgaaga attagttgaa gctgctgtca ttgatggtgc
     4321 aaatgattta cagattttct tcaaaatcat gcttcctctt gcaaaaccaa ttatgtttgt
     4381 tctcttcctt tatgcttttg taggacagtg gaactcatac tttgatgcaa tgatttatat
     4441 caaggatcca aacttggaac cattgcaact tgtacttcgt aaaattctca ttcagagcca
     4501 accaggtcaa gacatgattg gagcacaagc ggctatgaat gaaatgaaac gtttagctga
     4561 attgattaaa tacgcaacta ttgtcatttc cagcttgcca ttgattgtta tgtatccatt
     4621 cttccaaaaa tactttgata aaggaattat ggctggttca cttaaaggat aaaaaaagaa
     4681 aaaataaaag gagttttctc atgaaattca aaacattctc aaaatcagca gttttgttga
     4741 cagctagttt agcagtactt gcagcctgtg gctcaaaaaa tacagcttca agtccagatt
     4801 ataagttgga aggtgtaaca ttcccgcttc aagaaaagaa aacattgaag tttatgacag
     4861 ccagttcacc gttatctcct aaagacccaa atgaaaagtt aattttgcaa cgtttggaga
     4921 aggaaactgg cgttcatatt gactggacca actaccaatc cgactttgca gaaaaacgta
     4981 acttggatat ttctagtggt gatttaccag atgctatcca caacgacgga gcttcagatg
     5041 tggacttgat gaactgggct aaaaaaggtg ttattattcc agttgaagat ttgattgata
     5101 aatacatgcc aaatcttaag aaaattttgg atgagaaacc agagtacaag gccttgatga
     5161 cagcacctga tgggcacatt tactcattcc catggattga agagcttgga gatggtaaag
     5221 agtctattca cagcgtcaac gatatggctt ggattaacaa agattggctt aagaaacttg
     5281 gtcttgaaat gccaaaagct actgatgatt tgattaaagt cctagaagct ttcaaaaacg
     5341 gggatccaaa tggaaatgga gaggctgatg aaattccatt ttcatttatt agtggtaacg
     5401 gaaacgaaga ttttaaattc ctatttgctg catttggtat aggggataac gatgatcatt
     5461 tagtagtagg aaatgatggc aaagttgact tcacagcaga taacgataac tataaagaag
     5521 gtgtcaaatt tatccgtcaa ttgcaagaaa aaggcttgat tgataaagaa gctttcgaac
     5581 atgattggaa tagttacatt gctaaaggtc atgatcagaa atttggtgtt tactttacat
     5641 gggataagaa taatgttact ggaagtaacg aaagttatga tgttttacca gtacttgctg
     5701 gaccaagtgg tcaaaaacac gtagctcgta caaacggtat gggatttgca cgtgacaaga
     5761 tggttattac cagtgtaaac aaaaacctag aattgacagc taaatggatt gatgcacaat
     5821 acgctccact ccaatctgtg caaaataact ggggaactta cggagatgac aaacaacaaa
     5881 acatctttga attggatcaa gcgtcaaata gtctaaaaca cttaccacta aacggaactg
     5941 caccagcaga acttcgtcaa aagactgaag taggaggacc actagctatc ctagattcat
     6001 actatggtaa agtaacaacc atacctgatg atgccaaatg gcgtttggat cttatcaaag
     6061 aatattatgt tccttacatg agcaatgaca ataactatcc aagagtcttt atgacacagg
     6121 aagatttgga caaaattgcc catatcgaag cagatatgaa tgactatatc taccgtaaac
     6181 gtgctgaatg gattgtaaat ggcaatattg atactgagtg ggatgattac aagaaagaac
     6241 ttgaaaaata cggactttct aattacctcg ctattaaaca aaaatactac gaccaatacc
     6301 aagcaaacaa aaactagagg ttgattatgg gagataagaa atacacagta gaaaaagcca
     6361 atcgttttat agcagaaaat aaacatctcg ttaatactca atataagcct gaagaacatt
     6421 tttcagctga gattggttgg atcaatgatc caaatggatt tgtctatttt cgtggagaat
     6481 accatctctt ttatcaattc tatccatatg atagtgtttg gggacctatg cactggggac
     6541 atgctaaaag taaggacttg gtgacttggg agcacttgcc agtggcactt gctcctgatc
     6601 aagattatga ccgaaatggt tgtttctcag gctctgccat tgtcaaggat gatcgcctct
     6661 ggctcatgta cactgggcat atcgaagaaa aaaccggtgt ccgccaagtg caaaatatgg
     6721 cattttcaga tgacgggatt cactttgaaa agatttccca aaatccagtt gcaactggat
     6781 cagacttgcc agatgagttg attgctgctg atttccgtga tccaaaactc tttgaaaaag
     6841 atggacgcta ttactccgta gtagctgcca aacacaagga taatgtgggc tgtatcgttc
     6901 tactagggtc cgataaccta gtagaatggc agttcgaatc catcttttta aaagggggag
     6961 aacaccaagg ctttatgtgg gaatgcccag attacttcga gttagatggg aaagattgcc
     7021 ttattatgtc acccatgcgt tatcagcgtg agggagactc atatcataac atcaactcat
     7081 cgcttttgtt cacgggtaag gtagattgga gagaaaaacg ttttatccca gaatcagttc
     7141 aagaaattga tcatggccaa gacttctatg cgcctcaaac attgttggac gatcaaaatc
     7201 gtcgtatcct gattgcttgg atgcagacat gggggcgtac ccttccaacc catgaccaag
     7261 aacacaaatg ggcatgtgct atgactttac ctagaattct aagattggaa gatggcaaac
     7321 taagacaatt ccctgttaaa aaaggccaat atcaaatcca aatagataaa gattgtcatt
     7381 accacttagg aaatgataca gattatcttg aatttggtta tgacagtaat gcgcagcaag
     7441 tttacattga tcgtagccat cttattcaaa aaattctagg tgaagaagaa caggacacta
     7501 gtcgacggta tgtagatatt gaagctaaag aattggaagt tgttctagat aaaaattcca
     7561 tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc aacttattac ttaacggtgc
     7621 cagctgagct atcacgaatt gattaaaaat taagttattt ctcctaaaga aaaagttctc
     7681 tttctaaaat agtggaaaga ggactttttg tgttttgggt atataagctt agtttatggt
     7741 atttgtaaaa ttggtgttgg attatgattt aagctagttt tctaaagaat ttgaaaaaaa
     7801 ttttatttaa gcaaaaaaac cttggttcca aggcttttcc tgttgtatgt agatgccccc
     7861 tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca gctgagctaa
     7921 ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc
     7981 aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga cggcctacat
     8041 gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa cacttaagtg
     8101 tgaagtcgta caccacagcg tttctatact tatatgatac cactttttca aaaaaaatca
     8161 agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaacgat cgatagcttc
     8221 ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga aatagtgatg
     8281 attacgaatt ttttctggca gatagtcttg cttgatccaa tttccaggat agttgtgtgg
     8341 atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc catcacgcag
     8401 gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct tatccatagc
     8461 tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat tggcaatgag
     8521 aatgcgggct tctgggaacc caatcttctg ggcagcatcc agagcagtca cggtatgaat
     8581 ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca agcgacgagc
     8641 gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac tggcatccac
     8701 atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac cgtctccatc
     8761 cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta aggtgatgtg
     8821 gcgaatgccc ttgtcatttt cggaagtaga gagaacagcc aagtccagtg agttgaaggc
     8881 agagcgaagg tctccgtttg tagaggtcgc aatgaaatcc agcgcctcct catctagttc
     8941 tactggaaaa tcaaaaccac gctcagggtt acttagagct atctgcaggg cctctttgac
     9001 gtcttggtta gacagaggtt ccaactcaaa aatttgaaca cggctacgaa tggcaggagt
     9061 gacagaaaag aaaggatttt cagtcgtagc gccaatcatg atgaccagac cactttccaa
     9121 gagaggcaag aggaagtctt gcttggtttt atctagtcta tgaatctcgt ctagtaatag
     9181 gacgagacca ccagagaatt tagcctcttc cgcaatttct tgcaatcgct ttttactatc
     9241 aactgtcgca ttgaaagttc gaaaggcata ctttgttgtt ccagcgatgg cagaggcaat
     9301 actggtcttg ccgattcctg gaggtccata gagaatcatg gaggacaggc gattggcttc
     9361 caccatgcgg cggatgattt ttccaggtcc gaccagatgt tcctgaccga tgacctggtc
     9421 gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc tttctaacgt
     9481 ggatttgagt agaatgactc atctactata tcttactatg tccattctag cctattagtt
     9541 gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt ttactattta
     9601 atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct caaaatagga
     9661 tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg aatgtcattg
     9721 tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggaact accaagtcag
     9781 gaaattttga tttttacaaa acaaattcgt cattggattc ttagtgatca agttatttca
     9841 gggaaaagaa aacttttctt ccgggaagat actccaaaag agattttaga tttgtacgaa
     9901 aacattaaat ctaaacttga ttttgcttac caagaagttc attctaataa tgggttgaaa
     9961 aaatatgaaa aatagaataa ttgatgtttt tgaagtagta aatcgcctcc ttgtaataac
    10021 tgttgaaaat cctgatttcg aagacttgag agttaatcat actcaatgaa aatcaaagag
    10081 caaactagga aactagccgc aggctgtact tgagtacggt aaggcgacgt tgacgtggtt
    10141 tgaatttgat tttcgaagag tatcagtttg taaaaattgg agataaaaaa tatagagtac
    10201 gcagtgttcc tatgattcat tcaactccgc ctcaatctgt cttagatcga gatactttta
    10261 caattgacta tacagatgat gaattgctcg ataaagaagc agtttttact actcattaga
    10321 aaaataggta tgaataaatt ggcttccctt agaaccacat ctaggggctt ttatgtataa
    10381 tagaataata agtatcactc ctttacaata cgtgtaacac gtgttataat ggtgttgtca
    10441 ggaggtaaaa gcgctatgcc tatgacacaa aaagagatgg ttaaactcct tacggcccat
    10501 ggttggataa agactagagg cggtaaaggc tcccatatta aaatggaaaa gcaaggggaa
    10561 agacctatca caatccttca tggtgagctg aataagtaca ctgaaagagg gataagaaag
    10621 caagctgggt tgtaaaattc agcccctgct ttttgatatg gaggtagtga aatgttagtt
    10681 acgtatccag ctttatttta ttatgacgac acagacggaa cagaagcgac ttattttgtc
    10741 catttcccag attttgaata ctcagctaca caaggagagg ggatttctga ggctttggct
    10801 atggggtcgg agtggctagg gataactgtt gcagatttga tagagagtga tggagagtta
    10861 cctcagccat cagatatcaa tagcttgtct ttaattgata atgatccttt taaagatgat
    10921 gaagatttcg tgtcaaccta tgaccttgat aaatctttta tttctatggt atctgttgat
    10981 gtatcagaat acctaggaag tcaggaaccc attaaaaaga ctttgaccat atcaaaatgg
    11041 gcagataagt tgggacgaga aatggggctt aacttttctc agactttgac agacgctatt
    11101 gcagataaga aagttcaagc ctaagattaa gcgtggtatc gtggtaatag tcaataaaaa
    11161 agcacgtcca cttgtgctag ttactcgcct attgatttta tagatttatt agccctttcg
    11221 agggcttttt atattgattt ttatgagaaa tgaagaaatc agacttttaa gaaaatcact
    11281 gataccaagg gtttaaatga ggtaatatgg tataattagg acataaaata attttgtggt
    11341 aagatggtag tatctatttt agcatatttc cgagcaatcg gggcgattaa agagtcgcat
    11401 agaaagagga caaaatggca acatacggat ttttagatat tttagaggaa gagttggaca
    11461 agaactttcc ctttgacttt gagattagct gggacaaacg caaccatgcg gtagaagtga
    11521 gttttctatt ggaagcgcaa aatgctgcag gtgtggagat ggtggatgaa gacggagagg
    11581 tttcatcaga tgacattctt tttgaggaag cggtcctttt ctacaatcct gccaagtcaa
    11641 cagtcaatga ggaagactat ttgactgtta ttccttacct gcctaaaaaa ggattttccc
    11701 gtgaattttt agcttatttt gcgcttttcc ttaaagatac tgctgaggtt gggctagatg
    11761 tcctcatgga ctttttggaa gacccagaag cagaggaatt tgtcatggaa tggaaccaag
    11821 aagtctttga agaaggaaaa attggcttgg aaaagggaga attttatcct tatccaaaat
    11881 actaggagtt ggttggaggt gttatgaaga aaattgggac ttatttggtt tatgtgctag
    11941 ctgttgtctt tattatgcta gcttttgctt gtggaacaat cgcatttgca gagttggggt
    12001 attccgcagt tttagccttt acttttggtt atgccttcgc tcttctaagc atgtatttaa
    12061 tctttattct tcatgagctg ggtcatgctt tttgtggcta cttgacaggc tatcggctgg
    12121 tggcttttgg attaggacat tttattttga ccaaaaagtc aggcaggttt catcttagta
    12181 gaacagccat tctgaaaaat gttggtgctc aatacattgg tttaaaagag gatgaaagcg
    12241 atcaaagaat catcctgatg ctttcaggag gcttgatggt tcatctcggc ttgatattat
    12301 tggcgatatt gtttggattt ttgacaagaa gctggtattt tgcagggact tggatttttc
    12361 ttaatttatc tttcttccta aataacattt tgccagtcga catcaccgat ggagcaaaaa
    12421 tttgggaatt actacaacac cctgaaaata ccaaatacgc ctacctggta ttgagacatt
    12481 ctgcccagac cttgctagct cctcaagaat atgatttgaa agactttgtt caagcagttc
    12541 ctgaggatgc acgagggagt tttgcggatg gtgtattagg tatgcaaggt gaagtttcca
    12601 ttttggaagg gaaggaagaa gtagctaaac agcagtttca agcattactt gagaggacaa
    12661 ctactccgat gatgcagaca gttgcccaac tatccctgct tcatatcgcc ttgttggaag
    12721 gagattttga gcaagcggag caatatgcta gtattcgaca ggtcaaatcg tttctgtctc
    12781 tcaaactgtc caatcttcaa gtgatacaag cctggtatca attaaaggtg aagaaagatg
    12841 tagatcgaac tcgtaaggct ctcaagattg ctagacagaa aatggatagt agtcgaatgt
    12901 tgagggatga gaaaagatat tatgaaaact ggttagccga gctggaaaag gaaatgttag
    12961 aaggaactga agatggaact agaaatttct gatttcacag gttgcaaaat tgctttgttt
    13021 tgtggggata agcttttgac tatcttacgc gatgataagg caagtattcc ctgggccaat
    13081 atgtgggaac tgccaggtgg tggacgtgaa ggtgatgaaa gtccttttga gtgtgtagcg
    13141 cgtgaagttt atgaagaact gggcattcat ctgactgaag attgtctgct ttggagtaag
    13201 gtttacccaa gtatgctttt tgcagacaaa cagtccgttt ttctagttgg tcagttgaca
    13261 cagaaccagt ttgacagtat cgtatttgga gatgaaggac agggctatca gctgatgaat
    13321 gttgaggaat ttcttagttc cagtcaagtt gtgcctcagt tgcaagagag attaaaagat
    13381 tatttaaaag taagtgatta gaaaggatgg ttcggttaaa tttctaaact gaacccgccc
    13441 taaacacggt gccaaaaaga taaacttctc ttagacacaa gcgtcttcag agaatttcct
    13501 attttggttt tgtgttttac gggcttggta ttaataatgg aaacatggca agagttaaaa
    13561 gttacagtga agcgtgaggg agaggagttg gtttccaatc tcttgattga gctgggagcg
    13621 caaggagtcg caatcgaaga cagtatggac tatgtgggaa atgtggaccg ctttggagag
    13681 attttcccag aggtggagca gcaagaagaa atcgtagtga cagcctacta ccctgacacg
    13741 gtggatgtga cagtggttga ggcggatttg caggctcgtc tagcagaatt gacagatttt
    13801 atggatttgg gagagttaaa aataggtacg actgccttgg ctgaggaaga ctgggcagac
    13861 aactggaaga aatactatga acctgctcgc atcactcatg atttgaccat cgttccctct
    13921 tggacagact atgaggcgac tgcgggagaa aaaattatca agctggatcc tggcatggct
    13981 tttggtacgg gaacccaccc aactaccaag atgagccttt ttgccttgga acaggttctt
    14041 cgtggtggcg aaacggtgct agatgtggga actggttcag gggttctctc tattgccagc
    14101 tcgcttctgg gggctaaaga aattttcgcc tatgacctgg atgatgtggc agttcgtgtg
    14161 gctcaggaaa atattgagct caaccctgga atggaaaata tccatgtagc ggcaggcgat
    14221 ttgcttaaag gcgtggagat tgaagcagat gtcatcgtgg caaacatctt ggcggatatc
    14281 ctcattcatc tgacagagga tgcttatcgc ttggttaagg atgaaggtta cctgatcatg
    14341 agtggcatta tcaaggataa gtgggacatg gtgcgcgagt tggctgaatc agctggattt
    14401 ttcctcgaaa ctcacatggt tcaaggggaa tggaatgcct gtgtctttaa gaaaaccaag
    14461 gatatctctg gtgtgattgg aggctagcat gcagcagtat tttgtaaaag gcagtgctat
    14521 ctctcctgtc actatcgaga acaaggaaac cagtaagcat atgtttcagg ttatgcgctt
    14581 gaaagaagag gatgaggtta ccttagtctt tgatgatggc atcaagcgct tggcgcgcgt
    14641 gctggatatg gaaaatcgtc agtttgagtt ggtccaagaa ttaaatgaca atgtggaact
    14701 accagtccaa gtgaccatcg catctggatt tcccaaggga gacaagctgg agttcatcgc
    14761 tcaaaaagta accgaactgg gtgctagcca aatctgggcc tttcctgcag actggtcagt
    14821 tgccaagtgg gatggcaaga aattgggtaa aaaagttgaa aaactagaaa aaattgccct
    14881 tggagcagcc gagcaaagca agcgtaatat tgtaccaagt attaaacttt tcgagaaaaa
    14941 agcagatttt ctagctcagc tggaccagtt tgactttatc atagtagcct atgaagaatc
    15001 agctaaagaa ggagaagccg ctgcgcttct gcaagcagtc actggtcttg aaacaggagc
    15061 caaactgctc tttatctttg gtccagaagg cggtctctca cctgcagaaa tcgaaagttt
    15121 tgaagctaag ggagccgttt tggtaggcct aggtcctcgt attttgcgag cagaaacagc
    15181 accgctttac gccttatcag cccttagtgt tttagtagaa ttagagaaat aagaggaaga
    15241 aaatggaaca aaaacaccgt tcagaatttc cagagaagga actctgggac ttaacagccc
    15301 tataccaaga ccgtgaggat ttcttgcgtg caatcgagaa agctcgtgaa gacatcaacc
    15361 agtttagccg tgattacaag ggcaatcttc acacttttga ggatttcgag aaggcctttg
    15421 cggaattaga acagatctac attcagatga gccatattgg caactatgct tttatgcctc
    15481 agacgacgga ctatagcaat gacgaatttg ccaatattgc ccaagctggg atggaatttg
    15541 aaacagatgc cagcgtagcc ttgaccttct ttgacgatgc cttggtggta gcagacgagg
    15601 aagtcttgga ccgtttgggt gaattgcctc acttgacggc agctattcgt caggccaaaa
    15661 tcaaaaaagc ccactatcta ggggctgatg tggagaaggc cttgaccaat ctcggtgaag
    15721 ttttctatag tccgcaggac atttatacta agatgcgagc tggggatttt gaaatggctg
    15781 actttgaagc ccatggcaag acctataaaa acagctttgt cacctatgag aatttctacc
    15841 aaaatcacga ggatgctgag gttcgtgaga aatccttccg ttccttctca gagggacttc
    15901 gtaagcacca aaatacggct gcagcagcct atctggctca ggtcaagtct gaaaaactct
    15961 tggctgatat gaagggatac gactctgtat ttgattatct tctagctgaa caagaagtgg
    16021 accgtgtcat gtttgaccgc cagattgacc tcatcatgaa ggactttgca ccagtcgctc
    16081 agagatacct caagcatgtt gccaaggtaa atggtcttga aaagatgacc tttgcagact
    16141 ggaaattgga cttggacagc gccctgaatc ctgaagtgac tattgacgat gcctatgatt
    16201 tggtcatgaa gtcggtagaa cctttggggc aagaatattg tcaggaagtt gctcgttacc
    16261 aagaagagcg ctgggtggac tttgctgcta acagtggcaa ggattccggt ggttatgcgg
    16321 cggacccata tcgcgtacac ccttatgtac tcatgagctg gacaggccgt ttgagcgatg
    16381 tctatacctt gattcatgaa atcgggcatt ctggtcaatt catcttttca gacaatcacc
    16441 aaagctattt caacgcccac atgtcgacct attatgttga agcaccgtca accttcaatg
    16501 aattgctact cagtgattac ttagagaacc agtctaatga cccacgtcaa aaacgcttcg
    16561 ctctggctca tcgcttgaca gacacctact tccataattt catcacccac ctcttggaag
    16621 ccgccttcca gcgtaaggtg tatacattga ttgaagaagg ggagaccttt ggagcaagca
    16681 agctcaacag cattatgaag gaagttttga cagatttttg gggcgatgcc attgaaatcg
    16741 acgacgatgc agctttgact tggatgcgcc aagctcacta ctatatgggc ttgtatagtt
    16801 acacttactc tgctggtctt gtcatctcga cagctggtta ccttcatctt aaaaactcag
    16861 aaactggagc tgaagactgg ctcaatctcc tcaaatcagg tggtagcaag acaccacttg
    16921 agtcagccat gattatcggt gctgatattt caacagacaa accactccgt gataccatcc
    16981 aattcttgtc tgacacagtt gaccagatta tcgcctacag tgctgagttg ggggagtaag
    17041 gggaatagaa aaattttcta gaatgatgtt tatgggcttg ttaagcgtca ttctatttgt
    17101 cttagttgta gctattttca aaaatgtcgt tgaaggtcgt gatgttaaat ttgaacttac
    17161 tgtagaactg gtattgatag ttatttacgt cattttatat cagattgtat ttaattgaga
    17221 attcaatatt gagtcattta agactgcctt tttgaacagt tgctagaaat gtagaggtat
    17281 tgaccatgta tcaagattta ctaagaaaaa tagcagaaga aaaaccaaat tataaccagg
    17341 aagaaatcca gtggttgttt gatcatttgg gaaatccttc tccagaaatt cgtgatgacc
    17401 tttcaaatca aggcttgcac tatctttcaa aagaaaagga tacaacagat ttctcaagtc
    17461 agtatggttg ggttcatgct tttgcacatg gagccgattt actgacagag gtggtttgtc
    17521 atccagactt tcctataaac agaattcatg aagtatttga catacttggc caactattta
    17581 aaagaatgtc gattcgcttt acagatgatg aggattggcg tttagcaaga gtgatctatg
    17641 aacctatttt acaagggaag ttggagcaag aacaagtagc ttcttggata aaaactgttg
    17701 attttccgat agaagaaagg gaggattttt acaaattttc caactttaga tcctgtctgg
    17761 tggaagtcta tgtccaactt gaccagagaa atagtttaca agatgacctg aaagaagcta
    17821 tccagtcttt tcaatactag agattagcta atagttctat gattttcaaa aaatttccaa
    17881 tcaattttct tgaaaccctt tcctactttt gatagactag tatctagttt ttgaaaaaag
    17941 gagaaagaaa atgaaaaaat ttgttgctga gttaatcggt acgttcatgc ttgtgttcgt
    18001 tgggacagga gctgttgttt ttggaaatgg tcttgatggc cttggtcacc ttggaatcgc
    18061 ctttgccttt ggtttggcaa tcgtggtggc agcctactca atcggaactg tttcaggtgc
    18121 tcacttgaac ccggctgttt cgattgctat gtttgtaaac aaacgtttgt catcttcaga
    18181 acttgtaaac tacatccttg gtcaggttgt tggagctttc atcgcttctg gcgcagtctt
    18241 cttcctcttg ggtaattcag gtatgtcaac tgctagtctt ggtgaaaatg ccttggcaaa
    18301 cggtgtcact gtctttggtg gtttcttgtt tgaagtcatc gcaactttct tgtttgtctt
    18361 ggttatcatg actgtgactt cagaaagcaa gggcaatggc gcgattgctg gtttggtaat
    18421 cggtttgtca ttgatggcga tgattcttgt cggattgaag attactggac tttcagtaaa
    18481 cccagctcgt agcttggcac cagctgtctt ggtaggcggc gcagcccttc aacaagtttg
    18541 gattttcatc cttgcaccaa tcgctggtgg agttcttgca gcccttgttg caaaaaattt
    18601 ccttggaaca gaagaataat tgaaactcaa aaagccttgc tcctcatctt gaggaacagg
    18661 gctttttcgt atgatactct tcgaaaatct cttcaaacca cgtcagcttc accttgccgt
    18721 aggtatggtt actgacttcg tcagttctat ctgcaacctc aaaacagtgt tttaagctga
    18781 cttcgtcagt ttcatctaca acttcaaaac actgctttga gcaacctgcg gctaacttcc
    18841 tagtttgctc tttgattttc attgagtatg agtttagcgg ttgtcaattt tctctggata
    18901 aaggtcgtgt tggaagaggc gttgttctgc caagccctca tacttagttc cttgcttacc
    18961 gtagttgtag taggggtcga ttgaaatgcc accgcgcgga gtgaattttc cccagacttc
    19021 taaatagcga gggtctagca agttgaccaa gtctttcccg atggtgttga tacagttttc
    19081 gtggaaatct ccgtgatttc ggtagctaaa tagatatagt ttgagggatt ttgactcgac
    19141 acagagcttg tcaggaatgt aggaaatatg aatcgtcgca aagtctggtt gagcagtgat
    19201 ttgtcccagc agagacatat cgaggatatg gtgacgaatg ccctgttcct tagcgatttc
    19261 tctagcaatt tgaatttcga ggtgatgacg ttggccgtag gcaaaggtga cagcttcgac
    19321 tgtttcatag tgttgcatgg tccagaaaag gcaggttgtt gaatcttgac cgccactaaa
    19381 gacgaccaag gctgattgac gtttcatagt actccttcca aaatgggaaa tgttcagagc
    19441 acgcaaaaag ctcccattag ggagctaaaa aataccaaat cgaggttttt ttagcgatgg
    19501 catatcccaa acatcgtaat attctactta tatagtaaaa tgaaataaga acaggacaaa
    19561 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    19621 agtttcaata tactatagtc tagcatattt tttgaaaaat ggcaaagggc aagaaaaaag
    19681 agaccaaaga aagtacttgg tctctcgttt gattagctca attcagcaat gatggccttg
    19741 atttgttctg ctgtgtgaac acctgcaacc tgtttgacaa cttggccgtc ttttttgaag
    19801 agaagagttg gaatagacat gattccaaaa gcacgagctg tgtttggatt ttcatcaacg
    19861 tccattttaa cgattttcaa gacatcttct gaaagttctt cagacaattt gtccaagatt
    19921 ggaccttgca tacgacatgg accacaccaa gttgcccaga agtctactaa gaccaaaccg
    19981 tcttttgttt cttgttcgaa tgttgcatct gtaattgctt ttgccattgt atttctcctt
    20041 tttttagtta tattggctta aatcttgttt catgagatag aagaagatat ctccataagt
    20101 cccatggtag tccaaattat gacccttgta agttaatttt tggacagggt agtagtctgc
    20161 gacgccgata aggcaagctt gttgcgaacg ttcaaagtct tcataagact cgaaagtcac
    20221 agttctttcg ttcttgctgg catctatata ggtaatttca atcatattta aaactccttt
    20281 gtttaatgct aactttattt tactccttat aaaagagaat gtcaagaaaa atgattgcgc
    20341 acgcaacttt ttttaaaatc atcttaaatc aagaaatcca aacctgcttc caagctttct
    20401 tcgacagtct tttgtagcga ggccagtgtc ttttgcccat catttgtcag gcagataaaa
    20461 ctagagcgtc tatcttgatg gcaacacatg cgactgagta gaccgcaatt tttagcttcc
    20521 aagcgagcca ccatcctaga aactgcgctc gggctcagat gaagcttatc tggcaggtca
    20581 atctggcgta gagatttttc ttcagccaag tccagatagt agagcaggta gaactctttc
    20641 aaggtcagac tttgctcgct ctgttgggca atggtctctt ccaagagact ttcaatttct
    20701 ttctgacgcc gattgaagtc aaaccatttt tccaaatagg tcatagtgtc tcctttcttt
    20761 ttagagtcat aaaatagaag aaagtccatt aacgggcagt ctctgcgtca caagatgatt
    20821 gcgcatgcaa taattatact acttttcaag aatgctggca agctctgttt tttagtggtt
    20881 ttatttttta ctgtccatat ttttggtaaa aatcaacttt tacttggatg aaggttttgg
    20941 cttcacgtag gagttgaaga agggtggcgc gggtttcaaa ctcttctctt gtcttgggca
    21001 gactgcggtt ccggaagact tccagataac tttcaatttc atctagcaaa tcagaagcag
    21061 gattggtctg gctcagttga ccagcaattt ttgaaaagag ctgcgctaaa atcaggcttt
    21121 cactggcggc aaggtgacaa gtgttaatct gttgggccat gtttctcagg atacgacttt
    21181 gtcgttgtct catctcaaag tagtggatat ggtagtcggt ctggtgaaag aggtggtcag
    21241 agtgatccaa atagaccagt ctgagggctt ctttcaaaag cgtgtctaat tctgctacca
    21301 gctgtgctcg gttgcgtccg tctcctctgg ataaatagta tttgaagcgc tggaggatat
    21361 cttttaactt ttcttccacc agcgtgtggt agtgctggat tttcttttct cgtgaaggca
    21421 tgtagagatt gaccagtaaa gcaaatcctg taccgatagc aaagagaagg aattcattga
    21481 ctagaaggtc tggagaggtt gactcttgaa ccaagagatg gctaaccaaa acagtgcttg
    21541 gtgtgatacc aatttcccag cccatcttgt aggctaaagg aacgtagaag gccagataga
    21601 ggccgagact ccagatatga aatccgctca aatgaaaagc tagaacaccg atagccagag
    21661 ctagaagcat agaaaaaaga cgattgcgag ccagttttaa agtacttcta cgcgtatcag
    21721 ataggctcaa gagagcgata attccagccg aaactgctga cgaaagattg agaaaataag
    21781 caagcaggca ggcaagacag gtagctaaga tgagcttggt cgtacgttgg ctaatagaca
    21841 taagaatttc ctaataagtt agaataaaag cgtaaaagac aagacatgag caggcttgcc
    21901 ttgatgagtt attttttacg ggttgctgcg tattcggcaa cggcggtaaa gaggacatct
    21961 gtagaagagt taagggctgt ttcacatgag tcttagatga caccaatcac aaaaccaacc
    22021 ccaacaactt gtatggcaat atcgttagaa ataccgaaaa ggctacaagc aactgggata
    22081 agaaggaggg aacctctggc aatacctgaa gcaccacagg ctgagatagc tgctaccaca
    22141 ctgaggacaa aggttgtggc aaagtcaaca ggaattccaa gagtgttaac tgcagcaagg
    22201 gtcaaaaggt taatggtaat cgctactcca gccatattga tagtagaacc gagtgggata
    22261 gaaacagaat aggtatctgg gttgagtcca aggtcatggc agagtttcat gttgacagga
    22321 atgttagccg cagaactacg agtgaaaaag gctgtcacac cgctgacacg gaggcagttc
    22381 caaactagag ggtaaggatt gcgtctcata aagaagaagg caatcaaagg gtgaccacaa
    22441 gggcaacaaa aagcatagtc gttactaata gaaccaataa aataccgtag ttggtaaggc
    22501 ttccgactcc cttgtcagaa atggttttaa aaacaagacc aaggcttcca aatggagcca
    22561 gattgatgat ccattcgaca attttagaag tcacgtcagc gatagttttt agcaattctt
    22621 tactattttt actggcttct ctcatagcga ttccaaaaat gactgcccaa gataagattc
    22681 taatatagtt agcagtaaac agggcgttga ctgggctgtc aaccagtttg agcaagaggt
    22741 tgctgagaac ctgcccaacc ccatctggtg gtgcaatttc agtattggca ctatttaggg
    22801 taatttcaat agggacgatg aaacttgcta gtacagctac aagagcagcg gcgaaagtcc
    22861 ctatcatagg atatacaaga aaacaacagt tttcatattg ctatcttgtc ccttttgatg
    22921 ttggaaaggg cattggcaac gagggcaaag actaggatag gagcaacagc ttttagacct
    22981 ccaacgaata aatccccgag tagcccaatc cctgagagat taggaagggt cagtcctagg
    23041 attccccaca aagcatacca atcaagatac gcttgacaag gcttgcctta ttccaagcat
    23101 gaatgattct tttcataata atctcctttt tgtgtagtga ttatgattat agtataaatg
    23161 atagacaaaa tcaagaattt tctgtctatt ttttgaatat ttatggagaa tgagactgat
    23221 gaaaatatgg tataatgaaa taaaggagtt ttatatgcaa aaatttattc aggcttatat
    23281 tgaaaagcta gatgtgacaa ccattatcga gaatattcta accaaggtca tttctctttt
    23341 actgcttttg attgtatttt atattgctaa aaaaatgctt cataccatgg tgcagagaat
    23401 tgtcaaacct tctctaaaaa tgtctcgtca tgatgtcgga cgccaaaaaa ccatctcacg
    23461 tttactagaa aatgtgttta attatacgct atatttcttt ttactctact gcattttgtc
    23521 gattttaggt ttgccagttt ctagtttgct ggctggagct ggtattgctg gggtagcgat
    23581 tggtatggga gcccaaggct ttctgtctga tgtcatcaat ggctttttca tcctctttga
    23641 acgtcaactg gatgtgggag atgaggtcgt tctgacaaat ggaccgatta ctgtatcggg
    23701 taaggttgtc agtgtgggaa ttcgtacgac acagcttcgt agcgaggagc aagcccttca
    23761 ctttgtccct aaccgaaata tcacagttgt tagcaatttc tcacgcacag actagacctg
    23821 ttattttaag taatttgtgg tacaatagag ggagtttaat aaggagaaaa gatggtttta
    23881 gaaaagcagt tgggcaatgg ttgtacctgg atagacctag acctaggaaa gttgaataaa
    23941 ctagaagacc tttctgaaat ttacggtttg gacaaggaaa ccattgaata cgcactggat
    24001 agaaacgagc gcgcccacat ggactaccac cgtgaaagtg ggacggttac ctttatctat
    24061 aatgtcctag acgtaaaaaa ggacaaggcc tactatgaga cttttcccat gacctttatt
    24121 gtcgagcatc gtcgcctgat taccattagt aataccaaga acgcctatgt cattgaacag
    24181 atgactcgtt atctggagag ccatgacacg ctttcgattt ataagtttct ctttgccagt
    24241 ctggaaatca tcagcaatgc ctactatcct gtcattgagc agatggacaa gagtagggat
    24301 gaggtcaatg acctcttgcg ccagcgaact accaagaaaa acctctttgc cctgtctgat
    24361 ttggagactg gtatggttta tctaacggca gctgccaaac aaaatcggat tttgttagag
    24421 catattcaag gtcatgcctt gtatcgtagt tttgatgaga ttgagagaga acagtttgat
    24481 gatgccatga ttgaggctca tcagctggta tccatgacag acctaatctc tcagatttta
    24541 cagcagcttt cagcctctta caacaatatt ctaaacaata atctgaatga caatttgaca
    24601 accttgacta tcatttcagt cttgctagct gttttggcag tcgtgacagg ctttttcgga
    24661 atgaatgttc ccttgccttt aacagatgag ccccatgctt ggctctatat cagtttggct
    24721 agtgcaggtt tgtggattgt tttatccttg ttactaagga aaattgcgaa aaaaagttaa
    24781 gaaaaggagc cagaatggcg attgaaaatt atataccaga ttttgctgtg gaagcagtct
    24841 atgatctgac agtcccaagc ctgcaggcgc agggaatcaa ggctgttttg gtcgatttgg
    24901 ataataccct cattgcttgg aacaaccctg atggaacgcc agagatgaag caatggctac
    24961 atgaccttcg ggacgcgggt attggcatta tcgtagtgtc aaataacacc aaaaaacgcg
    25021 ttcaacgagc agttgagaaa tttgggattg attacgttta ctgggccttg aagcccttca
    25081 catttggtat tgaccgtgct atgaaggaat tccactatga caaaaaggaa gtggtcatgg
    25141 ttggtgacca gctcatgaca gatatacgag cagcccaccg tgcagggatt cggtcaattt
    25201 tagtcaaacc cttggtccaa catgactcaa tcaaaacgca gattaaccga actcgtgagc
    25261 gtcgtgttat gagaaaaatc actgaaaagt acggaccgat tacatataaa aaaggaattt
    25321 aactatggaa gaaattctct gtattggttg tggagcaacc attcagacga cagataaagc
    25381 tggtcttggt tttacccccc agtcggcact tgaaaaaggt ttggagactg gcgaagtcta
    25441 ttgccaacgc tgtttccgtc tccgccacta caatgaaatc acagatgtcc agttgacgaa
    25501 cgatgatttc ctcaagctct tgcacgaggt gggagacagt aatgccttag tggtcaatgt
    25561 cattgatatc tttgatttta atggatctgt catcccaggt ttaccacgtt tcgtctctgg
    25621 caatgatgtc ctcttggtag gaaataaaaa agatatcctt cctaagtcag ttaagtctgg
    25681 taagattagc cagtggctca tgaaacgtgc ccatgaagaa ggtcttcgtc cagtcgatgt
    25741 ggtcctaact tcagcacaaa ataaacatgc cattaaggaa gtcattgaca agattgaaca
    25801 ctaccgtaag ggccgcgatg tctatgtggt cggtgtgacc aacgttggaa aatcaactct
    25861 aatcaatgct attatccaag aaatcacggg tgatcagaat gtcatcacta cttcacgctt
    25921 cccagggaca accttggaca aaatagagat tccgcttgac gacggatctt atatttacga
    25981 tacgccggga attatccacc gccaccagat ggctcactac ttgacggcca aaaacctcaa
    26041 gtatgtcagt cctaaaaagg aaatcaagcc taagacctat cagcttaatc ctgagcaaac
    26101 cctattttta ggtggtttgg gacgctttga ctttatagca ggagaaaagc aaggatttac
    26161 tgctttcttt gataatgaac tcaaactcca tcgtagcaag cttgaaggag ctagtgcttt
    26221 ctacgataag cacctgggaa ctcttctgac accaccaaat agcaaggaaa aagaagattt
    26281 cccaaggcta gtccagcatg tctttaccat taaagataag acagacctag tcatttcagg
    26341 cctaggctgg attcgtgtaa caggcatagc aaaagtcgcc gtctgggcac cagaaggcgt
    26401 cgccgtcgtc acacgaaaag caattattta agcacagaaa ggaaagggtt gtctgaattt
    26461 gggcgagcaa ggcgagcccc atagagaata cttttcgctg tggtgtaagt tggtacaagt
    26521 gattgtacca actgcggaaa atttgagacc ttaggctcaa attttagtca tgaaagtccg
    26581 aaggactttg ctgacgtccg tcaccacttc agaaaagtat aaaaagaaac tcttttaaag
    26641 aaattatgtc attaacatca aaacaacgtg ccttcctcaa cagccaggca cacaccctca
    26701 aacctatcat ccaaatcggg aaaaatggac tcaacgacca aatcaaaacc agcgtccgtc
    26761 aagctcttga tgcgcgtgaa ttaatcaagg ttactctctt acaaaacaca gatgaaaaca
    26821 tccacgaagt agctgaaatt ttggaagaag aaatcggtgt ggatacagtc caaaaaatag
    26881 gacgcatctt gattttgttt aaacaatcta gcaagaaaga aaatcgcaag atttctaaga
    26941 aagtcaaaga aatctaagac cgaaactcca aataactgtt tttatagaga aataaagggg
    27001 actagcctat gacaatcgaa ctattgactc cctttaccaa ggtagagttg gagccagaaa
    27061 tcaaggagaa aaaacgcaaa caagttggga ttttaggggg gaattttaac cctgttcaca
    27121 atgcccatct cattgttgcg gatcaagtac ggcaacagtt gggactggat caagttcttc
    27181 tcatgcctga ataccaacct cctcacgttg ataaaaagga aaccatccct gaacaccatc
    27241 gtctcaagat gcttgagttg gcaattgagg gaattgacgg cctagtcatt gaaaccattg
    27301 agttggagcg caagggtatt tcctacacct acgacaccat gaagattttg acagagaaga
    27361 atccagatac ggattattac tttatcatcg gtgccgacat ggttgactat ctgcctaagt
    27421 ggtaccgaat tgatgaactg gttgacatgg ttcagtttgt gggggttcag cgtccacgct
    27481 acaaggcagg gacttcctat ccagttatct gggtggacgt accgctcatg gatatctcgt
    27541 ccagcatggt gcgggacttc attgcccaag gtcggaaacc caactttctc ctacctcagc
    27601 cagtgctaga ctacatcgag aaggaggggc tctactgatg tcctatcaag actatatcaa
    27661 ctgctcccgt gaggccttgt tggaaaaaat ggcagagctt ctacctgaga aacgtctaac
    27721 ccattgtcta ggtgtggagc gtgccgctat ggaattagct cagcgctttg gtgtagatgt
    27781 tgagaaagca agtctagcag gtcttcttca tgactatgct aaaaagttgt cagatcagga
    27841 atttctagac ttgattgacc gttatcagct agatttcgac ctcaaaaact ggggtaataa
    27901 tgtctggcat ggtatggtcg gaatttacaa aattcaggaa gatttggatt tgcatgattc
    27961 tgaaattctg cgagccattg aaattcatac agtcggagct ggtcaaatga cagacctaga
    28021 taaggtcatc tacgtcgcag actatatcga gcacaatcgg gcatttcctg gagtggatgt
    28081 ggcgcgtgag attgcaagtc tatcgctcaa taaggcggtg gcctacgaaa cagctcgtac
    28141 cgtggagtat ctagctcatc agggattccc catctatccc caaacccttg aaacctataa
    28201 cgcctttgtg cactatttga aagaggacta aatgaagacg gcttttataa tcattgatgt
    28261 tcagaatgtt ttagtagaaa ctgggttcca gacaaaaagt ctattggaaa aaatttctta
    28321 tttacaaaac caggctagaa gcaagaatat tgaaattatc tatgttcaac atattgagaa
    28381 ctctgaagct caaacatcag aagattggca gttatctgcg cttttaaatc gaaaacctgc
    28441 tgaaaaggtc tttcagaaga agtataacag tattttcaaa gaaactggct taaaagaata
    28501 cttggataag caggggattg aaaaattagt tttatgtggt atgcagacag aatattgtgt
    28561 ggatacctct gtcaaggttg cctttgaata tggctatcag cttattgttc cagaaggtgc
    28621 tgtcacaacc tttgatgggg atgacattcc agcagaaacg attaatgaat tttatgagga
    28681 catttgggag gagcgctttg cagatgttct agattacaaa catattttct aaaaagagga
    28741 ttaaatgaac gaaaaagaat tactagaact agtcgtgaaa gcggctgatg agaaacgtgc
    28801 ggaggatatc ctcgcacttg atgtacaaga tttgactagt gtgacggact actttgtcat
    28861 cactagctca atgaatagcc gtcagttgga cgctatcgca gctaatatcc gtgaaaaagt
    28921 agctcaagca ggctttaaag gtagccatgt cgaaggcgat gcagctggag gctgggtctt
    28981 actggacctc ggtgctgttg tcgtgcatat cttttcagaa gaaatgcgtg cccattataa
    29041 tctagagaag ctatggcatg aggcgaattc agtagatatt tcagaagctc ttgcttagaa
    29101 gatgaactca gttgtagtca actgggtttc tttgcttatt ttagaaaaat tgatagaaag
    29161 gtaaagggct agtggtgttt accatggagc tcttagtatc atgattatgg cgacttatga
    29221 aacctttgcg gcggtctatg atgcggtcat ggacgatagt ttatacgaca aatggacgaa
    29281 tttttctctg cgtcatttgc ctaagaccaa ggagagaaag aaactcttgg aattggcttg
    29341 tgggacagga attcaatcag tgcgcttctc tcaggctggt tttgatgtga ctggacttga
    29401 cttgagtgcg gatatgttga agattgcgga gaagagagca acttcagcca agcaaaagat
    29461 tgcttttata gaaggtaata tgctgaattt gtccaaggca gggaaatacg attttgtcac
    29521 gtgttattcg gactctatct gctatatgca ggatgaggtg gaagtagggg acgtctttaa
    29581 ggacgtgtac aatgcgctga atgaagaggg agttttcatc tttgacgtgc actcgaccta
    29641 ccagacagat gaagtattcc ctggctattc ctaccatgaa aatgcggaag attttgccat
    29701 gctttgggat acatatgagg acgaagctcc tcactccatc gtgcatgagc tgactttctt
    29761 tatcaaggag gctgacggtt cctttagtcg ccacgatgaa gtacatgagg agaggactta
    29821 tgagatcttg acctatgata tcttgctgga acaggctgga ttcaagtcct tcaaactcta
    29881 tgcagacttt gaggataagg aaccaacaga aactagcacc cgttggtttt ttgtggcgca
    29941 gaagtaggag aacatcatga ccatcacagg tattatcgca gagttcaatc cttttcataa
    30001 tggccataaa tacctgctgg atcaggcaga gggactgaaa attgttgcca tgtcagggaa
    30061 tttcatgcag cgtggagagc ctgctattgt ggataagtgg acaagggccc agatggcgct
    30121 ggaaaatggc gcagacttgg tagtggaatt gcccttttta gtcagtgttc aggcagctga
    30181 tttctttggt caaggagctg tggatatctt ggatcgcttg ggcattgata gtctagtttt
    30241 tgggacagag gaagttcgag attatcagaa aatcgctgac ttatacacag agaaaggtgc
    30301 tgagatggag aaatttgtgg aaaatctgcc tgattccctt tcctatcccc agaaaaccca
    30361 atctatgtgg aaggaatttg ctggtcttga tttttcaggt aataccccca atcatgttct
    30421 tgctctggcc tatgcaaagg cggttgcagg acgaaatatc aagctgcata cgattcagcg
    30481 tcagggggca ggttaccatt ctgtgaataa agatgtggac tttgcctcgg cgacagccct
    30541 ccgtcaacat cagaaggacc aagatttctt agaacgcttt atgccttctg ttgccctatt
    30601 tgagcaggcc agtaaggtga tctgggaaga ctattttccc ttgctccgct atcaaatctt
    30661 gtcaaatccc gacctaacca ccatctatca ggtcaatcaa gaaatggctg tgcgcattaa
    30721 agaagctatt aaaacagccc agtctgtaga agagttggtc gaggcggttg cgaccaaacg
    30781 ttacaccaag gcgcgtgtca gacgcctatt gacctatatt ttggtgcagg ctagagaaaa
    30841 tgtcttgcca gaagccattc atgtccttgg atttactgaa aaaggcaggc aacatctcaa
    30901 gtctctgaaa ggacaggtca atctagtcag ccgaattggc aaagaacctt gggatgctat
    30961 gacccaaaaa gcagaccaga tttaccaact aggaaagcca agtatagcag agcaaaattt
    31021 tggaagagtg ccgattagaa tagaaacaag ctaagtctac cgaaaggtag gctttttgag
    31081 attttttacg aataatactc ttcgaaaatc aaattcaaat cgcgtcaacg tcgccttgcc
    31141 gtactcaagt acagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtata
    31201 aatagataga aaagaaaatc ttgtacaagt tcctgacaat ttctttcttt tcgtgtataa
    31261 tagtggaaaa gagctaaaac gaggtatggt tatggaagca gtcctttact caacattccg
    31321 aaatcattta aaggactaca tgaagaaggt aaatgatgaa tttgagcctt tgacggtggt
    31381 caataaaaat ccagatgagg acattgtagt tctttcaaag agcgaatggg acagtattca
    31441 ggaaaccctg agaatcgctc aaaataagga gttatcagac aaggttttgc gaggaatggc
    31501 tcaagtccgt gctggaagca ttcaggtcca tgtgattgag gagtgatgaa tgctactcaa
    31561 gtttacagaa gatgcgtggg cagattattg ctactggcaa aaccaagata aaaaaacact
    31621 aaaaagaatc aataaattaa tcaaggatat tcaacgcgat ccatttacag gaataggaaa
    31681 accagagcca ctcaaatatg attaccaagg agcctggtca cggcgtattg atgcagaaaa
    31741 tcgcttgatt tatatgatgg atggagatag cgtggctttc ttgtccttta aagatcatta
    31801 ctaagtctat tgaaaggtag gctttttctc aagtctctac taaactacta tttctaaaaa
    31861 acaagtttat tttggcaaat gtgttccaaa ttccccaaaa catattctat tttaggtttg
    31921 tgaaaatcac ttttttatgg tagaatgtaa aagaatgtat gtcattcgga ataacaataa
    31981 aatgaggtaa aaacatggaa atcatgtcgc ttgcgattgc tgtttttgcc gtcatcattg
    32041 gtttagtcat tggatatgtc agcatctcag ctaagatgaa atcatctcag gaagctgcag
    32101 agttgatgct tttaaatgct gaacaagaag caactaattt acgtggacaa gctgagcgtg
    32161 aagcggattt acttgttaat gaagccaaac gtgaaagcaa gtctcttaaa aaagaagcac
    32221 tattggaggc caaagaagaa gccagaaaat accgtgaaga agtggacgct gaattcaaat
    32281 cagaacgtca agaactcaaa caaatcgaaa gtcgtttgac agagagagct actagccttg
    32341 accgtaagga cgacaatttg acgagtaaag aacaaacact tgaacaaaaa gaacaaagta
    32401 tttctgatag agcgaaaaac cttgatgcgc gtgaagagca attagaggaa gtcgaaagac
    32461 aaaaagaagc agaactagag cgtattggtg ctctgtctca ggcagaagca cgagatatta
    32521 tcttggctca gacagaggaa aacttgacca gggagattgc cagtcgcatt cgcgaagctg
    32581 agcaagaggt caaggaacgt tctgacaaaa tggccaagga catcttggtt caagctatgc
    32641 aacgtatcgc tggtgaatat gtagcggagt caacaaactc aacagttcat ctgccagacg
    32701 atactatgaa gggacgcatt attggtcgtg aaggtcgtaa cattcgtacc tttgaaagtt
    32761 tgacaggggt cgatgtgatt atcgacgata caccagaagt ggtgaccttg tcaggatttg
    32821 atccgattcg tcgtgagatt gcccgtatga ctatggaaat gttgctcaaa gatggtcgta
    32881 tacatccagc tcgtatcgaa gagttggttg agaaaaaccg tcaagagatt gacaataaga
    32941 ttcgtgaata cggtgaggct gctgcctatg aaattggtgc gccaaacctt catccagact
    33001 tgatgaagat tatgggacgt ttgcagttcc gtacttcata tggacaaaat gttttgcgcc
    33061 attcgattga ggttgctaag ttggctggta tcatggcgag cgaacttggt gaaaatgcgg
    33121 ctcttgcccg tcgtgctgga ttccttcacg atatcgggaa agccattgac catgaggttg
    33181 aaggtagcca cgttgaaatc ggtatggaat tggcccgtaa gtacaaggaa cccccagttg
    33241 tggtgaatac gattgctagt caccacggag atgttgaagc tgagagcgtg atagcagtta
    33301 tcgtcgctgc agcagatgcc ttgagcgcag cccgtccagg tgctcgtagt gagtctcttg
    33361 aaagctacat caagcgtctc catgatttgg aagaaattgc taacggcttt gaaggagtgc
    33421 aaactagctt tgcccttcaa gcaggacgtg aaattcgtat catggtcaat ccaggaaaaa
    33481 tcaaggacga caaagtcaca atcttggctc acaaagttcg taagaaaatt gaaaacaatc
    33541 tcgattatcc aggaaatatc aaggtaaccg tgattcgcga gcttcgtgca gtagattatg
    33601 ctaaataaat aagaaagagc agttgaaaaa ttactgcttt tttgttacac tagatagaaa
    33661 gactgtaaag gataatctgg ctttttgcca ttattctaga gaaatgttat ttcacagatt
    33721 gactaaaagg agacacaatg gcagaccgag gcttactaat cgttttttct ggtccttcag
    33781 gggttggaaa aggaacggtt agaagagaga tttttgagag ttctgaaaac caatttcaat
    33841 attctgtatc gatgacgaca cgcgcacaac gtcctggaga agtggacggt gttgactatt
    33901 tcttccgtac tcgtgaagaa tttgaagagc tgattcgtca aggacagatg ttggaatacg
    33961 cagaatatgt cggcaactac tatggaactc ctctgaccta tgtcaatgaa accttggaca
    34021 agggaatcga tgttttcctt gaaattgaag ttcagggtgc tcttcaggtc aagaaaaagg
    34081 ttccagatgc tgtctttatc ttcctgacac caccagattt ggatgaattg caagaacgct
    34141 tggtaggtcg tggaacagat agtgcagaag tgattgccca acgaatcgaa aaggccaagg
    34201 aagaaattgc cctcatgcgt gagtatgatt atgcgattgt caacgatcag gtgcccctag
    34261 ctgctgaacg tgtcaaatgt gtgattgaag cagaacactt ctgtgtggat cgtgtcattg
    34321 gtcactatca ggagatgtta ccaaaatctc caactacccg ataaaattta gaaaataggt
    34381 acaagcaaat gatgttaaaa ccctctattg ataccttgct cgacaaggtt ccttcaaaat
    34441 attcactcgt aatcttggaa gcaaaacgtg cccacgaatt ggaagcaggt gccccagcaa
    34501 ctcaaggttt caagtctgaa aaatcaactc ttcgcgcttt agaagaaatc gaatcaggaa
    34561 acgttacaat tcacccagat ccagaaggaa aacgtgaagc agtgcgtcgc cgtatcgaag
    34621 aagaaaaacg ccgcaaagaa gaagaagaaa agaaaatcaa agagcaaatt gctaaagaaa
    34681 aagaagatgg tgaaaaaatt taaggttggg gggactcaat cttatttttt ctattgcaag
    34741 aatgtactga caaggaggag gtgagaagat ggccctagct aagattatcg tagatgtgcc
    34801 cttgatgcag acggaccagc cctatagtta caggattccg gaggaatttg agggaatgct
    34861 ggaagttggg atgcgggttc atgtgccttt tggtaagggt aatcgcctga ttcaagggat
    34921 tgttcttggt ttggagtccc aatcagatgg agaagagatg gagcgagatt taaaagatat
    34981 tgcagaggtg ctggattttt ctcctgttct cacgccagaa caactctggc tggctgagga
    35041 gttacgcaaa tctgtcttct cctacaaaat ctctatcctc aaggccatgc ttccgggatt
    35101 tctgaattct agctatgaca agattctcta tcctctggaa ggcttgagtc aggaagaacg
    35161 agtacgcctg tttgattcag aagattcgct agccttttct tctctggatt taggtaagca
    35221 agctgaaatg atgcgtttga ctagaaaagg cctgcttggt ctggaatatc aggcagtcga
    35281 tcaaaagaag gtcaagaccc agtcttggta tgaggttgac catgctcaat tagaaggtgt
    35341 tgagatttct acacgtgcca agaaaaagtt ggaactgaga gattatctgc tgtctcatcc
    35401 agagagcgct tccttggcta gcttgttaga gtcctactcg cgagagcaag ttaacttctt
    35461 tgtggatcaa ggtgctgtta ctatagtcca aaaggaagtt cgacgctcgg ctgcttattt
    35521 tgaaggaatt gaagcaagta gacctttgga gttaaatcca gaacaaagac aggcgcgtga
    35581 tgcggttgtg agttctattg gcagttctca acctcccttt ctacttcaag ggattacagg
    35641 aagtgggaag accgaggttt acttgcagat tatccaaggt gccctggata agggcaagac
    35701 agctattttg ctggtacctg agatttcctt gactcctcag atgaccgagc gttttatagc
    35761 acgttttggg gacaaggtag ccattcttca ctcaggatta tccaatggtg aaaagtatga
    35821 tgaatggcgc aaggtggagc gtggcgatgc ccaagttgtt gttggtgcca gatctgctat
    35881 ctttgctcct ctgaaaaatc tgggtgtcat gattattgat gaagagcatg aagcggctta
    35941 taagcaggac agcaatcccc gttaccatgc cagagaggta gctattttac gggctcagta
    36001 taatcaagca actctggtac ttggatctgc aacgccgagc ttagagagcc gggcacgtgc
    36061 tggcaaaggc gtctatcaac acttacgtct aacccaacgt gccaatcctt tggctacaat
    36121 ccctgaggtt caagtgattg actttcgaga ctatatcgga caaaatgaga cgtcaaactt
    36181 tacgcctcct ttgctagagg ctatccaaga ccgtctggtt aaaaaagagc agatggttct
    36241 catgctcaat cgccgtggtt attctagctt tgtcatgtgt cgggagtgtg ggacggtgga
    36301 tacttgtccc aactgcgata tttctctgac cttgcatatg gataccaaga ctatgaactg
    36361 ccattattgt ggtttctcga aggatattcc tcaggtctgt cctaactgta agagccacag
    36421 tattcgttac tatgggacgg gaactcagaa ggcttatgat gagctagcag aactctttcc
    36481 ccaagctcgc attttgagga tggatgtgga tacgactcga aagaaaggca gtcaccaagc
    36541 cttgcttgac cagtttgggc gaggggaagc ggatatttta cttggtactc agatgattgc
    36601 aaagggtttg gattttccca atgttaccct agtcggagtt ctaaatgcgg atacggcctt
    36661 gaatctgcct gatttccgtt cttctgagag aaccttccag ctcttgactc aggtggcagg
    36721 tcgagcaggt cgggctgaaa aagcaggtca agtcttgata cagtcctaca atccgcagca
    36781 ctatgctatt cgatttgcca aggatcaaga ttacgaaggc ttttatgcct atgaaatggg
    36841 aatcagacga caactcggct atccacctta ctatttcacg attggtatta ccctttctca
    36901 caagaaagaa gaagaggttt tcaaacgtgc ctatgaagtc atgaacattt tgcggtcagg
    36961 cttgtcagag accagtccca ttctggggcc aacgccaaaa ccgattgccc gtacccacaa
    37021 cctctatcat taccagattt taattaaata ccgtttagaa gatgagctgg ggccgaccct
    37081 caaccaggtc ctggccttga ctcaagaacg ggaaaatagt gagctccgtc tcagcattga
    37141 ccatgagccg cagcaatttt tataagaagg agaagatatg acaaaactaa tctttatggg
    37201 gacccccgac ttttcagcaa cagtcttaaa aggacttttg acagatgacc gttacgaaat
    37261 tctagccgtt gtgacccagc cagaccgtgc tgttggtcgt aaaaaagtta tccaagaaac
    37321 cccagtcaag caggctgcca aggaagcagg attatctatc tatcaacctg aaaaattatc
    37381 tggaagtcca gagatggaag atcttatgaa gctaggagca gatggaattg tgactgctgc
    37441 ttttgggcag tttctcccaa gcaaactcct tgatagcatg gactttgctg tcaacgttca
    37501 tgcctccctc cttcctagac accgtggtgg tgcgcctatc cattatgcct tgattcaagg
    37561 ggatgaggaa gctggtgtga ccatcatgga aatggttaag gaaatggatg caggagatat
    37621 gatttctcgt cgcagcattc cgatcacaga tgaggacaat gttggcacct tgtttgaaaa
    37681 attggcgcta gttggtcgtg atttgctttt ggacactctg cctgcctata ttgctggtga
    37741 tatcaaacct gaaccgcagg atacgagtca ggttaccttc tctccaaata taaagccaga
    37801 ggaagaaaaa ctggactgga acaaaaccaa tcgtcaactc tttaaccaaa ttcgtggaat
    37861 gaacccctgg cctgttgccc atactttcct taagggcgac cgctttaaga tttatgaagc
    37921 cctaccagta gaaggtcagg gaaatccagg tgagattctc tctatctgca agaaagaatt
    37981 gattgtcgca acggctgaag gggctctatc cctcaaacaa gtgcagccag ctggtaagcc
    38041 taagatggac attgcttcct tcctcaacgg agttggacgt acattgactg taggagaacg
    38101 atttggtgac taaagtagaa acggctagaa gtttagctct agcagtgcta gaggatgttt
    38161 ttgtgaatca agcatattca aatattgcct taaataaaca cctcaagggg agtcagctct
    38221 ctgcagcaga caagggctta gtgaccgagc tagtctatgg aacggtagcc cgtaaactga
    38281 ctctggaatg gtacctatcc cactttatcg aagacagaga ccagttagac agctggctct
    38341 atgtccttct tctcatgagt gcctaccaac tccgctattt ggacaagatt ccagatcatg
    38401 ctgtggtcaa tgaagcagtg gaattagcca aactccgtaa aaaaggcagt gaaaaattgg
    38461 tcaacgctgt ccttcgccgt atcttgcgtg aaggctggcc agatattgct agcatcaagc
    38521 gaaaaaacaa gcgtgactcc attgcctatt ctctcccagt tttgctagtt gccaaactca
    38581 aggaagaata cggagaggag agagcaaaag ccatctttga aagcctgtta gtgcgaaaca
    38641 aagccagtat tcgtgtaaca gacctaagtc gaaaagagga aatccaagcc ttgttggagg
    38701 cgaatgattc ccttttagca accactggtc tggttaagga gcaggggcat tttgcagggc
    38761 ataatttgtt tgcggatgga gccattacca tccaagacga gtccagtcag ctggttgctc
    38821 cgacgcttga tttacaaggt gatgagcgag tgcttgatgc ctgtgcggct ccaggtggga
    38881 aaacagccca tatagcctct tatcttacga caggtcaggt tactgctctg gacttgtacg
    38941 accacaagtt ggatttaatt caagaaaatg cccaacgtct gggagttgaa gatcgggttc
    39001 aaactcaaaa attggatgcc agaaaggtgc atgagttttt tgaccaggat tcctttgata
    39061 agattttggt ggatgctcct tgttcaggaa tcggtctttt gcgccgaaaa ccagatatca
    39121 aatacaataa agaaacggca gatttcgcgt ccttgcagga aattcagtta gaaatattag
    39181 gtagtgtttg tcaaatacta ggcaaaggtg gtataataac ttatagcacc tgcactatcg
    39241 tctcagagga gaattttcaa gtcgttaagg cctttttaga gagtcatccc gagttcgagc
    39301 aggtaaaact agaacatgaa tgtaaggata tcatgaaaga cggctgtatc ctcattacac
    39361 ctgaattgta tggaagtgat ggattcttca tcagtcaatt tcgcaagata tcggattagg
    39421 aaggaactga cacatggaaa tttcattatt aacagatgtt ggtcagaaac gaacaaataa
    39481 ccaagactat gtcaaccact atgtcaatag agctggacgt accatgatta ttttagctga
    39541 tgggatggga ggtcatcgcg cagggaatat cgctagtgaa atggcggtca cagacctggg
    39601 tgtagcttgg gttgataccc agattgatac agtcaatgaa gtgcgtgaat ggttcgccca
    39661 ttacctagaa attgaaaatc aaaagattca ccagcttggt caggatgaag cttacagagg
    39721 catgggaact actttggaag tccttgctat tattgataat caggctatct atgctcatat
    39781 tggtgattcg cgtatcggct tgattcgtgg agaagaatac catcagttga cgagcgatca
    39841 ttccttggtt aatgaattgc tcaaggctgg tcaattgaca ccagaagagg cagaagctca
    39901 tccgcaaaaa aatattatca cccagtctat tgggcaaaaa gatgaaattc agcctgattt
    39961 tgggacagtt atccttgagt caggtgacta tcttttgctc aatagtgacg gcttgaccaa
    40021 catgatttca ggcagtgaga ttcgtgatat tgtaaccagt gatattcctt tagcagataa
    40081 aacggagaca cttgttcgtt ttgctaacaa tgcaggaggt ttagacaaca ttacggttgc
    40141 ccttgtttct atgaacgagg aggatgcaga atgatccaaa tcggcaagat ttttgccgga
    40201 cgctatcgga ttgtcaaaca gattggtcga ggaggcatgg cggatgtcta cctagccaaa
    40261 gacttaatct tagatgggga agaagtggca gtgaaggttc tgaggaccaa ctaccagacg
    40321 gacccgatag ctgtagctcg ttttcagcgt gaagcgagag ctatggcaga tctagaccat
    40381 cctcatatcg ttcggataac agatattggt gaggaagacg gtcaacagta tcttgcaatg
    40441 gagtatgttg ctggactaga cctcaaacgc tatatcaagg aacattatcc tctttctaat
    40501 gaagaagcag tccgtatcat gggacaaatt ctcttggcta tgcgcttggc ccatactcga
    40561 ggaattgttc acagggactt gaaacctcaa aatatccttt tgacaccaga tgggactgcc
    40621 aaggtcacag actttggtat tgctgtagcc tttgcagaga caagtctgac ccagactaac
    40681 tcgatgttgg gctcagttca ttacttgtca ccagagcagg cgcgtggttc gaaggcgact
    40741 gtgcagagtg atatctatgc catggggatt attttctatg agatgttgac aggccatatc
    40801 ccttatgacg gggatagcgc ggtgaccatt gccctccagc atttccagaa acccctgccg
    40861 tccgttattg cagaaaattc atctgtacct caggctttag aaaatgttat tatcaaggca
    40921 actgctaaaa agttgaccaa tcgctatcgc tcggtttcag agatgtatgt agacttgtct
    40981 agtagcttgt cctacaatcg tagaaatgaa agtaagttaa tctttgatga aacgagcaag
    41041 gcagatacca agaccttgcc gaaggtttct cagagtacct tgacatctat tcctaaggtt
    41101 caagcgcaga cagaacacaa atcaatcaaa aacccaagcc aggctgtgac agaggaaact
    41161 taccaaccac aagcaccgaa aaaacataga tttaagatgc gttacctgat tttgttggcc
    41221 agccttgtat tggtggcagc ttctcttatt tggatactat ccagaactcc tgcaaccatt
    41281 gccattccag atgtggcagg tcagacagtt gcagaggcca aggcaacgct caaaaaagcc
    41341 aattttgaga ttggtgagga gaagacagag gctagtgaaa aggtggaaga agggcggatt
    41401 atccgtacag atcctggcgc tggaactggt cgaaaagaag gaacgaaaat caatttggtt
    41461 gtctcatcag gcaaacaatc cttccaaatt agtaattatg tcggccggaa atcttctgat
    41521 gttatcgcgg aattaaaaga gaaaaaagtt ccagataatt tgattaaaat tgaggaagaa
    41581 gagtcgaatg agagtgaggc tggaacggtc ttgaagcaaa gtctaccaga aggtacgacc
    41641 tatgccttga gcaaggcaac tcaaattgtt ttgacagtag ctaaaaaagc tacgacgatt
    41701 caattaggga actatattgg acggaactct acagaagtaa tctcagaact caagcagaag
    41761 aaggttcctg agaatttgat taagatagag gaagaagagt ccagcgaaag cgaaccagga
    41821 acgattatga aacaaagtcc aggtgccgga acgacttatg atgtgagtaa acctactcaa
    41881 attgtcttga cagtagctaa aaaagttaca agtgttgcca tgccgagtta cattggttcc
    41941 agcttggagt ttactaagaa caatttgatt caaattgttg ggattaagga agctaatata
    42001 gaagttgtag aagtgacgac agcgcctgca ggtagtgtag aaggcatggt tgttgaacaa
    42061 agtcctagag caggtgaaaa ggtagaccta aataagacta gagtcaagat ttcaatctac
    42121 aaacctaaaa caacttcagc tactccttaa aagcagatgg ataatcaaaa tgagtaatca
    42181 atctttgtca tgatttcatg gcaaagattt tttttgagtc cagatttgtg atagaataga
    42241 gggagttgat aaaaggagga aagcatggaa gaatcaaaag aattaaatgc cgtcattgat
    42301 gtgattatgc tagcggggac tattctcctt aaaagtggct cagaaatcca tcgtgtagaa
    42361 gataccatga ttcgaatcgc gcattcgcag gggattgtgg attgcaatgt ccttgccatg
    42421 cctgccgcta tctttttctc tattgaaaat accaatattt cgcgcatgaa gcgcgtgacc
    42481 tcctcttctt ataacatcga aaaagtctgc gatgtgaacc agatttctcg tcagctagtt
    42541 ggggggcaga ttgacttaga aacagccttt aagcaattga cggccttgca agctcaaccc
    42601 cttccctata ctaagttgca ggtaactctg gctgcgacct ttagtgctcc tttcttttca
    42661 gttatgttta gcggaaatat ctacgacgca cttggggcag gagtggcgac cttatttggt
    42721 tttgcctttt ccctctatgt ggaaaaattt atccgaattc cctttgtgac agcctttgct
    42781 ggagcctttg tctttgggat aattgcccag ttttgggctc gctacacagg ttttccttca
    42841 acggcagatt tgattatagc tggtgcggtc atgccgtttg taccaggtat tgccttgacc
    42901 aatgcggtcc gtgatattat gaccaaccac ataaactctg gtatgagtaa gatgtttgaa
    42961 tccctgctca ttaccctcgc tttaggggca ggaacttctg tcgccttggt attgatgaac
    43021 taatatgaca ctaacaacct ttttattaca agcagtagca agttttcttg ccattatcac
    43081 ttttttaatc gtactcaatg tgcaacggtc tatgctctta cctggaggga ttttgggcat
    43141 gactgtctgg ctaatctatc tcttgctcaa ggaaccgacc aatgtcattg tagctacctt
    43201 cattgcagcc attattggtt cttgtgtcag ccagatttta agtattcttt ataagacacc
    43261 tgctgtggtc tttatcttgg ccattttggc accgctggtt ccaggttatc tctcttaccg
    43321 aacaactgcc ttttttgtga caggggacta taataaagca ctggcaagtg cgaccttggt
    43381 tgtcatgttg gctttggtaa tctctattgg aatggctagc ggaacagtga ttctcagact
    43441 gtatcattat ataaaaacac atcgagtatc gtagacttta cagaaataaa agaattttct
    43501 gaaaaatgag ataaataaat taacaacgct ttctatatgt gcgagaatac cgcacttatg
    43561 aagaaattgc ggctgatttt ggtattcacg aaagcaactt aatccgtcgg agctaatggg
    43621 ttgaagtaac tcttgttcaa aggtggtgtt acgatttcaa gaactcctct cagctctgag
    43681 gacacggtaa tgattgatgc gacggaagta caaatcaatc gacctaaaaa aagaattagc
    43741 gaatgattct ggtaaaaaga aatgccacgc tatgaaggct caagcaattg tcacaagtca
    43801 agggagaatt gtttctttgg atatcactgt gaactattgt catgatatga agttgttcaa
    43861 aatgagttgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg gttatcaagg
    43921 gctcatgaag atatatcctc aagtacaaac tccacgtaaa tccagcaaac tcaagccgct
    43981 aacagttgaa gataaagcct ataaccatgc gctatctaag gatagaagca aggttgagaa
    44041 cattcttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa
    44101 acgcttcgga ttacgaatga atttgattgc tggcattatc aatcatgaac taggattcta
    44161 gttttgcagg aagtctacta ctttccttat tgtctgtaag tctactgacc ttgttgttta
    44221 tcccagtcat ggtttctagt tcgggctcag agtttcaaag tggatggcaa gagcatcaat
    44281 tgattgctga gaaggttagt aaaacacttg ataagacatt tgataaggat gtcagagaaa
    44341 ttccgaccag tcagttttat caaaaatttg tagatgagat ggtaaggact tactcaggaa
    44401 atttgatcct ccaggagctg ataactgtga atggagctta taaagctact tatatcggtg
    44461 aactctctag caactaatca ttctttaaaa tgatgaccaa taagaggctt gatttggtga
    44521 atcaagtctt ttttctctct tttactgcca tttgtgataa aatagtatag aacgattttt
    44581 tacatgaatg ataaaacaga ggtaaatatg acaatcggta ttgataagat tggttttgcg
    44641 accagtcaat atgtcttgaa attacaagac ttagcagaag cgaggggaat tgaccctgaa
    44701 aaattaagta aaggactctt actcaaggaa ttgagtattg cgcccctaac tgaggacatt
    44761 gtgaccttgg cggccagtgc tagtgactct attttaactg agcaagaaag acaagaagtt
    44821 gacatggtca ttgtggcgac cgagtcagga attgaccaga gtaaggctgc ggccgtcttt
    44881 gtgcatggct tgctgggcat ccagcccttt gctcgtagtt tcgagattaa agaagcctgc
    44941 tatggggcga cagctgccct ccattatgcc aaattgcatg tggaaaattc tccggagtcc
    45001 aaggtattgg tcattgccag tgatattgcc aaatatggta ttgaaactcc gggagaacca
    45061 actcaaggtg ctggaagtgt agctatgttg attacacaaa atccacgcat gatggccttt
    45121 aataatgaca atgtagctca gacccgtgac atcatggatt tctggcgacc aaattactcg
    45181 acaactcctt atgtaaatgg tgtctattct acccaacaat acttggatag tttgaaaacg
    45241 acttggcttg aatatcaaaa acgctaccag cttactttgg atgattttgc ggctgtttgt
    45301 ttccacttgc cttatcctaa attagcgcta aaaggcttga aaaaaatcat ggataagagc
    45361 ctgcctcaag agaaaaaaga tctcttacaa aagcattttg accagtctat tctctacagt
    45421 caaaaggtgg ggaatatcta cacaggttca cttttccttg gacttttgtc tctcttggaa
    45481 aatacagata gcttgaaagc tggggataaa atcgcccttt atagttacgg aagtggagct
    45541 gtggctgagt tcttcagtgg tgaattggtt gaaggatatg aagcttattt ggataaagac
    45601 cgtttgaaca agctcaacca acgaactgcc ctatccgttg cagactatga aaaggtcttt
    45661 tttgaggaag taaacttgga tgaaacaaac tctgcccagt ttgctggcta tgaaaatcaa
    45721 gattttgcct tggttgaaat tctcgaccac caacgccgtt atagcaaggt tgaaaaataa
    45781 tgaagataag ttggaatgga ttttctaaaa aatcatacca agagcgcctc gagctgttaa
    45841 aagctcaggc gctccttagt cctgagagac aagctagtct ggagaaggat gaacagatga
    45901 gcgtgactgt ggcagaccag ctgagtgaga atgtagtggg aactttttct ctgccttatt
    45961 cactggttcc agaggtactt gtcaacggtc aggaatacac cgttccctat gtgacagaag
    46021 aaccctctgt ggttgcggcg gccagctatg ccagcaaaat catcaagcgt gcaggtggtt
    46081 ttactgcaca agtccatcag cgacagatga ttgggcaggt agccctttat caagttgcta
    46141 atcctaaact agcgcaagag aagattgcca gcaagaaagc ggagctcttg gagcttgcca
    46201 atcaagccta tccttctatc gttaaacgtg gaggtggggc gcgtgatctg catgtcgagc
    46261 agataaaagg cgaaccagac tttctcgttg tttatattca tgtcgatacc caggaagcca
    46321 tgggtgccaa tatgctcaac accatgctgg aagccttgaa accagtctta gaagaactca
    46381 gtcagggaca gagtctcatg ggaatcctgt ccaactacgc gaccgattct ctggtgactg
    46441 caagctgtcg catcgccttt cgctacttga gccgccaaaa ggatcaagga cgagagattg
    46501 cggagaaaat tgcgttggct agtcagtttg cgcaggctga tccttaccga gctgctactc
    46561 ataataaagg aatttttaat ggtattgatg cgattttgat tgccactggt aatgactggc
    46621 gtgccatcga agctggggcc catgcctttg ccagtcgaga tggacgttat caaggtctta
    46681 gttgctggac gctggacctt gaaagagaag aattggtcgg tgagatgacc ctgcccatgc
    46741 ctgtagcgac taagggtggc tctatcggcc tcaacccacg tgtagctctc agtcatgatc
    46801 tactaggaaa tccttctgcc agagaattag cccagattat cgtgtccatc ggtcttgccc
    46861 aaaattttgc agccctcaaa gccttggtaa gtacgggcat ccagcaaggc cacatgaaac
    46921 tacaggccaa atccctagct ctcctagctg gggctagtga atctgaagtt gctcccctag
    46981 tcgagcagct tatcgcagat aaaaccttta acctagagac agcccagcgc tatctcgaaa
    47041 atttaagatc ataaaaaact cagacgaatc ggtctgagtt ttcttgtgtt taaatacttt
    47101 ttcctggtaa tagtgtaact ggtaagaagt aaccagttgt ggcgacttcc ttgccttcaa
    47161 tcttttgcaa gagaagatca atagtgagac aagcaatctc ttccaaaggt tgcttgatag
    47221 tagccaattg agggtagtaa ttttcgataa agtaggtccc atcatagccg atgaccttga
    47281 gcttttttgg gacagaaatg cccaattctt gagcgatttt aatgaccaga atagctgtca
    47341 aatcatccga agcaaaaatg gcatctggtt tttcccgggt caagatattc ttgatttcca
    47401 tctcttttct gacgggagaa aagtcactgg aaacattgat aataggagct tttgggagta
    47461 cggatgcaaa accagcgtgg cgcagtccgg ttggcgaatt agaattgtca ttccctgtaa
    47521 tcatgatgat agactgggca cctgtcttga ccaaggtttg ggcagcaaga accccaccag
    47581 catagttgtc agaggagacg acagggatgt ctggcgatag gtttcggtca aaggaaataa
    47641 tcggcgctgt cacacgattg tagtcttcga ttcctaggtt gtgactacca gaaatgatgc
    47701 cgtccacctg attggcttcc aacatttcga tgtattcgcg ttccttctca gaatcatgtt
    47761 cactgttgca gatgatggtc ttgtaaccat ttttgaagag ttggtgttcc aatttatcaa
    47821 tcaattctgc atagaaaaca ttggaaatat tggggaaaat caagccgatt aacttagctg
    47881 attttccttg cagactacga gctaggttgt tgggtttata gcctaattct ctcatggctt
    47941 cattgacttt ttggatggtt ttctcagata gatatccttt tttattgata acccgagaaa
    48001 cggtagtagg actgacgcct gcaagtttgg cgacatcagt tagttttgcg accataatct
    48061 aattcatagt aagttccagt tgggtttcca gatttgatca ggataccatt ttggtccgca
    48121 tgtgggaaga cacgaccaga aaatactttt tctcctttat tgatgaaaat ttcaaagaca
    48181 gagttatcga tgaagattgt agcagtagta gcctgattct cgatagggca agaacgagtt
    48241 gtcccaaatt cttgggcata ctgttctcca gcctggctac gatccactgt cacttgaccg
    48301 tttacaaggt caaagttgat tgaaagtccc ttaccttctt tatcagcaag taagacaatc
    48361 tcgctctggc tattagcttc caagttgagt tcaagttcgt aagtgttctt ggtttgggaa
    48421 cggtttgaga aggcttcttc agaagcacga aggtccttaa tagcagcgac tggatactgg
    48481 tagagcttgt cgtctttgat agtgagttcc ttgaccaaag agaaggttcc ttggtggtca
    48541 aaacggtcag atgggtaaga aacatctggc aaaccaagcc agctaactgc tagagcacgc
    48601 ccatcaggag cgttgaaggc ttgagttgca taggcttcga aaccgtaatc catgttttga
    48661 agttgagaca catctaccat tttggcattt ttagggtcaa aggaagcccc aatcttatac
    48721 atatttggaa agatattatc gtagtctaga actttcttat ccaatccttg tggacagtag
    48781 agaaggacag gttgttcctc tacaaagacc agattaggac attccatcat gtaggcagta
    48841 cggtcgttag caaagtcaag gtcgccaact gcttgccagt ttgtgtagtc gttattgaca
    48901 gccttgtaga gacgaacgaa accttttttc tccaagtcct gtccaccgac gacagcatag
    48961 tattgacctt taaagttaaa aatttgtgga tcgcggaagt ggtcagtaga gtctgctggc
    49021 tggtcaatca agatcttgtc aatctttgta atcttaccct ccttgtccat caaagcaccg
    49081 atctggtatg ggtgacggat ccagttttca tcgcgaacat ttcctgtata aaataggaat
    49141 aagttatcgc caaattgcat ggcagaacca gagtaggcac cgtggctatc taatggagta
    49201 tctggtaaaa ctttgattcc agtttcttta aagtgaacca aatcatcact ttctagctgt
    49261 gcccaagatt ttaaaccgtg ggctgcacca aaaggaaaat tctggtaaaa gaggatccac
    49321 ttgccatcaa agtaagaaaa gccatttggg tcgttgagaa gtcctgtttt tggctcaaca
    49381 tggtaatgag tatgccatgg agattgtgcc atattttcct ttatatgttg aatttcttct
    49441 tgcgtccaat cttgataaag tctgtaacga cgctcagttg tccattccat tcattcctcc
    49501 aaaaatctta tcacttttaa tagtaactgt tttcgataaa aaatgcaagc cttttatgtt
    49561 aaaaaagaga aaaaactgtc aaacgattat cataaaataa atacaggaaa tcaattaaat
    49621 ttttacgaaa atgtgaaaga taatgaaata aaagactttt taaccaaggt ttcaaactta
    49681 tttttcaagg aattcctgat gaaacagtca aaaacaatca atctaaagct tgcccattaa
    49741 gtggatagaa tattttttat gcaaaacgct tgacatattt ttaaaacatg ataaaataat
    49801 agtcgtaagg gcgaataaaa tcgctttcaa acaagaacaa aatgttatat aaggagattt
    49861 ttgctatgga ttatagtaaa gttgctgccg aggtcattga ggctgtcggt aaggataatc
    49921 ttgtagctgc agctcactgt gcgacacgtc ttcgcttggt attgaaagac gaagcaaaag
    49981 tgaatcaagc agctctggat aataatgcgg atgtcaaggg gacttttagc actaacggac
    50041 aatatcaaat tatcattggt cctggtgatg ttaacttcgt atatgcggaa attattaaga
    50101 aaactggttt gaaagaagtt tcgacagatg atttgaaaga gattgctaat aaagacaaaa
    50161 agttcaatcc attgatggac ttgattaaac ttttgtcaga catttttgtt cctattatcc
    50221 ctgccttagt tgcaggtggt ctcttgatgg ctttacggaa cttcttgaca tcaccagatt
    50281 tgtttggacc tcaatcaatt gaagatatgt atcctgctat caaaggcttc tcagctatga
    50341 ttcaattgat gtctgctgct ccatttatgt tcctccctgt tttggttggt atttcagcag
    50401 ccaagcgctt tggagcaaac caattccttg gtgcggcaat cggtatgatt atgaccactc
    50461 cagatttggg tggtaaagaa gccttctggg acatcttagg tttccatgtt acacaaacaa
    50521 actatgctta tcaggttatt ccagtccttg ttgcagtctg gttgttagct aatttagaaa
    50581 aattcttcca caagaaattg ccatctgcag ttgacttcac ttttacaccg cttttatcag
    50641 tgatgattac aggattcctt acctttacag ttatcggtcc tgttatgttg gttgtgtctg
    50701 atgcgattac aaatgcgatt gtatggttgt acaacacaac aggtgccttt ggtatggggc
    50761 tatttggtgg aacttactca ttaatcgtta tgacgggtct tcaccaatca ttcccagcaa
    50821 tcgaaacaca attgttgtct gcatacaata ataacggtac tggatttgga gactacatct
    50881 ttgttgttgc ttcaatggca aacgtagcac aaggtgcggc tactcttgca gtctacttct
    50941 tgacaaaaaa tgctaaaaca aaaggattgt ccagttcggc tgctgtttct gccttccttg
    51001 gtattacaga acctgctctc tttggggtaa acttgaaata caaattccca ttcttctgcg
    51061 cccttgctgg ttcagcaatt ggtgcctttg tagcaggttt aactcacgtt attgcagttt
    51121 cattgggagc ggctggattt attggattcc tttctattaa ggctggttca atccctatgt
    51181 atataattgc ggaaattatg tcctttgttg ccgcctttgc tttcacttat ttctacggga
    51241 aaacaaaagc agctagtgtc tttgctgatg aagctgccac agcaaccgca gaaacagtta
    51301 cagaacctac agtagaagca ccagtagtgg aagagactga tactcttcaa aatgaaacac
    51361 ttgtaactcc tatcgttggt gatgttgtcg ctcttgctga tgtcaatgac ccagtcttct
    51421 caagtggagc tatgggacaa ggtatcgctg tgaaaccaag ccaaggcgtg gtctatgcac
    51481 cagctgatgc tgaagtttca attgcctttc caacagggca cgcttttggt ttgaaaacaa
    51541 gaaatggtgc tgaagttttg attcacgttg gtattgacac tgtatctatg aacggtgacg
    51601 gttttgaagc aaaagttgct caaggtaata aggtgaaagc tggcgatgtt cttggaacat
    51661 ttgactcaaa caaaatcgct gcagctggac ttgatgatac aacaatggtt atcgttacaa
    51721 atacagctga ctacgcttca gtagctccag tcgcaacagg ttcagttgcg aaggggaatg
    51781 ctgtgatcga agtgaaaatc taatcaatcc tctctaatgt gaaaacgaac aaatgacatg
    51841 tttgttcgtt tttattagat agtaagattt acagaggaaa atctaaaaaa tagagacatt
    51901 tagactttcg aagtatgcta taataaagaa aataaaaaca agaggtttat catgacaaaa
    51961 ttatatggaa gcttggaagc gggcggtaca aagtttgtct gtgctgtcgg tgatgaaaac
    52021 tttaacgttg tagaaaaaac acaatttcca acaacaactc caatcgaaac aatcgataaa
    52081 accattgagt tcttctcaaa attcgataac cttgctggtc ttgcagttgg ttcatttggg
    52141 ccgattgata ttgacaaaaa ctcaaaaact tatggcttta tcacgacgac tccaaaacca
    52201 aactgggcaa atgtggactt gcttggtgcc cttcgtcgcg ccctaaacgt gccaatgtac
    52261 ttcacaacag acgtaaacag ctctgcttac ggtgaaatgg ttgcccgtaa caatgctggt
    52321 ggtcgtatcg aaaacttggt ttactacaca atcggtacag gtatcggtgc aggcgtcatc
    52381 caacgtggtg agtttatcgg tggtgtgggt caccctgaaa tgggtcatta ttatgttgct
    52441 agacacccaa tggatattga aaaagagttt aagggtgttt gtcctttcca taagggatgt
    52501 ctagaaggtt atgcagctgg tccaagtttg gaagctcgta caggtgtacg tggggaaact
    52561 attgaactca acaaccctgt ttgggatgtt caagcctact atatcgctca agctgcggtt
    52621 aatgcgacag tgactttccg cccagacgtg attgtctttg gtggaggggt catggctcaa
    52681 caacatatgc tggaccgtgt ccgtgagaaa tttacatctc ttcttaatgg ttacctacca
    52741 gtaccagatg tgcgtgacta tatcgtgacg ccagcagtcg caggaaatgg ttctgccaca
    52801 cttgggaact ttgttcttgc aaaagaagtt tcaaaataaa gcacaaaatc cgcttgggaa
    52861 accaaacgga ttttgtggtt gaaaacaata tttttgagcc tttccttaag tgattacgga
    52921 cggtagcgac tttcttcgaa attccatacc taaactttga gcctagtgtc tcaaagtttc
    52981 cgaatacctg aaaccattag atttcaggtg tttctatcac ggcggaaagg ctaggtaagt
    53041 cctcgcctca ctatcgaaaa atatgcatga tttccatacc aaagtatatt tagtatcaag
    53101 ctatagttaa tctacgcttt aaaaatccac ttgggaaacc aaacggattt tttacgtgtc
    53161 aaagcatttg ccagaaaaag tcaataatat aggtcagacc gtaggtataa accacgaggg
    53221 taaagggttt ggtcagaatg atgatggtca tgtagcgctt gaaactcatc ttggtcaggg
    53281 cagccagcat acagagaaag tcagctgggc taatgggcca aatcatcata aaaataaaga
    53341 agcggtcaaa acgattgccc ttatctagcc agccgatgta cttgtcgtag gtgcgcttgc
    53401 tgacgacaga ctggacaaag gcagctccgt ataggcgcac tagataaaag ataatggcac
    53461 agccaatcac gatgccgata tagttgtaga tagtcccgat gatgtgcccg tagataaaga
    53521 ccccagccac cgaggtcaag gcccctggaa tgatagggac gacagtctgt aaaatctgta
    53581 aaaagataaa gagaggtgga ccccagatgc ctgcctgctg gataaaggca gagagggttt
    53641 ccttggattg taaaatccca gcctgataag cccaaataca gaaaatcaaa ctcccaaccc
    53701 caccgacaat cgatgagata ttgataactc gctgcagaag gggagaaaca gctttcattt
    53761 gtttatcctg tgacatgtaa actcctcata gatagtatat ttctactata ccatattttg
    53821 gaggagaaag ggggaatgag tcttttttga taaggaatag aaagtaaata gcccttcgag
    53881 acttagaata ggtctgtcaa ctaaaggtta tatgcattct aggtttcgaa taatcgcaat
    53941 tccataaatt taaaagcatt ctaagtttcg aatagcttat ctgagataat tttgaggcat
    54001 tcgcgctttc gaatagtcat tttccctaaa gtttagatgt attctgaagc tagaaagact
    54061 aaaatctaaa agtagtaaga gtctctctct gatggacgta atttatggct agtatgaatc
    54121 ctttgaattg ttagttaatt ttaatattaa tcagttctga aataattact aaatatagtt
    54181 agatggtgaa ttaattattg ctaaatttca agttcaagtt agtcatccag aagtcttctc
    54241 tgggggactt gtagttcaag cattttttag gatagttgtt aatccacttt tcgatgaatg
    54301 cgacttcctt tgtagtcgtt ttcttagttc cctgaggtaa ccatctatga atgaacttgt
    54361 tgtgattttt attagatcct atagtggtgt gcataataga tatagcagat tgaaactaga
    54421 atagtataca tctacttcta aaacattgtt agaaatcaat ttgactgtcc tgatcaattt
    54481 gtcctgttct tatttcattt tactatataa tccttagaaa acatatcgga caagcggttg
    54541 aattccgttc cgtccattag tagataaagg attactcctt cttgaaatga cagatgaact
    54601 tgtttcttat aaaaatgtta tctgaaacta ttcgcttttt tccagaagtt ttagaggaag
    54661 aaaactttat gaggaaaaag gagttactca aataacaatt caggattaaa aatagacagt
    54721 tgaggagcgg aaggtataaa ttaagtttgc tactgtataa tggatttatc actaatactc
    54781 ttcgaaaatc tcttcaaacc acgtcagctt cgccttgccg tagatatagt tactgacttc
    54841 gtcagttcta tccacaacct caaaacagtg ttttgagctg acttcgtcag ttttatctgc
    54901 aacctcaaag ctgtactttg agcagcctac ggctagcttt ctagtttgct ctttgctttt
    54961 cattgagtat aaaagtgctc caggccatat tttacacagc aatagtcttc taaaaatgga
    55021 caaaaaacat tgtaaaggct atcaaaaagg agtataatga gtgcaagaaa tttcggaggt
    55081 gaaagatgct agaagtaaga agtctagaga aaagttttgg ctccaagcaa gttttgtttg
    55141 gtattgactt tcaagcgcga ccaggtcgta ttttgggact agtcggaaaa aatggtgctg
    55201 gaaaaacaac gattttccat agtattttga aattcctaga atatcaggga gaaatcggtc
    55261 tagatggtca ggatattcgt caggagacct atgctcggat tggttatctg cctgaagaac
    55321 gcagtctcat gcctaaattg acagttcttg aacaagttcg ctacttggcg actctaaaag
    55381 gcatggatgc caaagaagtc aaagaaaaac tccctcaatg gatgaagagg ttggaagtga
    55441 aaggaaagct gacagataaa atcaagagtc tgtcaaaagg aaatcagcag aagattcagc
    55501 tcattattac tctgattcat gaaccagacc tgattatctt ggatgagcct tttagtggat
    55561 tggacccagt taatacagaa ttgctcaaac aagtcatttt tcaggaaaaa gagcgcggag
    55621 caaccattat cttttctgac catgtcatga ccaatgttga ggaactttgt gacgatattc
    55681 tgatgatccg agatggccgt gtggtcttgc acggaccagt tcaggatgtc cgcaatcaat
    55741 acgggaaaac gcgtctcttt gtttcaagtg aacgaagcaa ggaagaattg gaaaatcttc
    55801 ctcatgtcaa acaggtgagc ttgaccaaac aaggcagttg gaaattgatt ttggaggatg
    55861 agagcgctgg aagggaactc ttcccaatct tgactcaagg tcaatatatc gcaacatttg
    55921 accaacaagc gccaactatc gatgaaatct ttaaactaga atcaggagtg gaagtatgag
    55981 aaatatgtgg gttgtaatca aggaaaccta tcttcgacat gtcgagtcat ggagtttctt
    56041 ctttatggtg atttcgccgt tcctcttttt aggaatctct gtaggaattg ggcatctcca
    56101 aggttcttct atggctaaaa ataataaagt ggaagtagtg acaacagtgc catctgtagc
    56161 agaaggactg aagaatgtaa atggtgttaa cttcgactat aaagacgaag caagtgccaa
    56221 agaagcaatt aaagaagaaa aattaaaagg ttatttgacc attgatcaag aagatagtgt
    56281 tctaaaggca gtttatcatg gcgaaacatc gcttgaaaat ggaattaaat ttgaggttac
    56341 aggtacactc aatgaactgc aaaatcagct taatcgttca actgcttcct tgtctcaaga
    56401 gcaggaaaaa cgcttagcgc agacaattca attcacagaa aagattgatg aagccaagga
    56461 aaataaaaag tttattcaaa caattgcagc aggtgcctta ggattctttc tttatatgat
    56521 tctgattacc tatgcgggtg taacagctca ggaagttgcc agtgaaaaag gcaccaaaat
    56581 tatggaagtc gttttttcta gcataagggc aagtcactat ttctatgcgc ggatgatggc
    56641 tctgtttcta gtgattttaa cgcatattgg gatctatgtt gtaggtggtc tggctgctgt
    56701 tttgctcttt aaagatttgc cattcttggc tcagtctggt attttggatc acttgggaga
    56761 tgctatctca ctgaataccc tgctctttat tttgatcagt cttttcatgt atgtagtctt
    56821 ggcagccttc ctaggatcta tggtttctcg tcctgaggac tcagggaaag ccttgtcgcc
    56881 tttgatgatt ttgattatgg gtggtttttt tggagtgaca gctctaggtg cagctggtga
    56941 caatctcctc ttgaagattg gttcttatat tccctttatt tcgaccttct ttatgccgtt
    57001 tcgaacgatt aatggctatg cggggggagc ggaagcatgg atttcacttg ctattacagt
    57061 gatttttgcg gtggtagcaa caggatttat cggacgcatg tatgctagtc tcgttcttca
    57121 aacggatgat ttagggattt ggaaaacctt taaacgtgcc ttatcttata aatagaagag
    57181 ccttgcgaaa gcgaggtttt taaaggtgaa aagggtggaa tcacgaacct aattatgtac
    57241 acattatgta aacaagttgc ttgaaaactc aattgtatag tgaactgaat ctggaatagg
    57301 ataatattac ttctaaaaca ttcttacaaa ttgatttgaa ttccaaaatc ccatcgttcc
    57361 gttcttattt cattttgcga tatagtgaaa ggaaataagt caactcacaa aaaacgcata
    57421 atatcaagga tttttaacac ttgatactat gcgttttcta attttaaaga ctttttgcct
    57481 ggtctctttt gttctatgag tatgttacat atctaggtaa aaattattta aagcaaatta
    57541 accttatttc tcaagatgta gtaggttccg agataaaaga tagctatgaa tatgagttct
    57601 ttaacaatgg ctatacctgc tcccatatag aaatggtcat tgagtcctac cagtgaattg
    57661 acatagaaat tagaactaag attgaagaaa agttcaataa atccaatgac gatttggata
    57721 ccaatgtagg ctgcaacagc gagtgctgta cggtattcat tgaaaagctg tccaatggaa
    57781 atagccaggt agatgcagag gattcctgaa atggtattta gtaggaagga tatacctgta
    57841 agaaagatct gagggagatg tgtttctaca aatgtaatca cataagaaag aggaatccat
    57901 tctggagctg ttaaagccag aataataaca gcacttagag ccaatacagc ggtgctaatc
    57961 aatgaccaga taaaggcacc gattagtttg gctgtgatga tatggtgttc agaaactggc
    58021 aaggtcaaag tcagatagcc ttgtcggtcg tagacactac ctttgaagcg tttaataatc
    58081 aagaaaatgg ttgaaatcgc aagtgtaagc atcaagccac caaagactgt agctagaaaa
    58141 agtagcatag tagcctgact ttcttggtaa ggtagatttt taaagccttg tgtctgtatt
    58201 ccgatgaggg cagaaaggac tagcacggct gcgtagaggg ctaaatacca cttgttaaca
    58261 tttttaaatt cgtagtgaac taaattccaa aacataaata atctcctttg cttaggcctt
    58321 aaattcctga cggaagagtt ggtcaatgga ttcacctgac tcgtagcgaa tatcatctac
    58381 atttccttga cggacgactt ttccgtcttt taggaagaca atttcatcca agattggctc
    58441 gatatcagaa atcaagtggg tagaaatcaa aacggtagaa gttggtgagt agttgttgat
    58501 aatggtattg aggatataag cacgggctgc tggatccacc ccaccaatgg gttcatccaa
    58561 aacatagaga cgagcatcac ggctcataac caaaatcagt tgaacctttt ctttgtttcc
    58621 ttttgatagt ttcttgagac gactattttc atcaatgccc aggtctgcaa gtagatgatg
    58681 agcgcgttca agattgaaat ctttatagaa ggtcttgaag taggttaggg cttctttgac
    58741 cttcatttgc tcattgagat aagtcgtatc aggcaaataa gctacaacgg ccttggttgc
    58801 tgggcttggg tccatgtcgt tgatgaggac acgtccttga tctggttgta agaggccatt
    58861 aattagttta atcagggttg tttttcctga gccgtttggc ccaagaaggc cgacaatttt
    58921 tccagctgga atgtcaagag aaacattttc aagggctggt gttgctccat atgatttgga
    58981 tacattttca aatgctagta atgacatagg cttaaactcc tttaatataa tcactgacta
    59041 cgcctggtag ttcttctttt tcatagccaa aatgggtcat ggaggaaacg aagtgttcca
    59101 attcttcttc tgataattgt ttgcgtgact gggcgattag ctccttatcc ttagtcacaa
    59161 atcgtccagt tgttcgcttg ctgtagacaa atccttctcg ttcaaggtct gataaggctc
    59221 tttggatggt attgggattg acaccagcct cgctagctag ctccctcacg gttggaagtt
    59281 gttgattggg ttccagtgta tgggaaacaa tctgaagctt gattttctcc ataatctgta
    59341 aatagatggg ttttttgttg tcaaatgtcc aggacatctt agtctccttt cttttaccct
    59401 attgtcttaa ttaaataata caacaaaaca aaaaacttgt caagcaaaaa gaagaattgt
    59461 tttgggaatc gcttaaaaaa tggtataatg aaaagaaaac gataaggagg gaaaggatgc
    59521 gttgtccaaa atgtggggct accaagtcaa gtgttatcga tagtcgccaa gcagaagaag
    59581 ggaacaccat tcgtagaaga cgtgagtgcg acgaatgcca acaccgtttt acaacctacg
    59641 aacgagtaga agaaagaacc ttagtggttg ttaaaaaaga tggcacacgg gaacaattct
    59701 ccagagataa aatctttaat gggattatcc gctcagccca gaaacgtcct gtgtcaagtg
    59761 atgaaatcaa catggtagtc aatcgtatcg aacagaaact ccgtggtcga aatgaaaatg
    59821 aaattcaaag tgaggacatt ggttcactcg tcatggagga gttggctgaa ttggacgaga
    59881 ttacctatgt acgttttgct agtgtctatc gtagttttaa ggatgtcagt gagttagaga
    59941 gcttgctcca acaaatcacc cagtcctcta aaaagaaaaa ggaaagataa atgaagccaa
    60001 ttgaccgttt ttcttatcta aagaataatc gggtgtcgca agatacctca tctctggtac
    60061 agtgctacct cccgattatc ggtcaggagg cactgagcct ttatctttat acgattagtt
    60121 tttgggataa tggtagaaag gaatatcttt tttcaagtat cctcaatcat ctcaactttg
    60181 ggatggatag actgataaaa tcattgaaaa tcttatctgc ttttaatctc ttgactctct
    60241 atcaaaaggg ggatgtttat cagctagccc tccatgctcc tctatctagt caagacttct
    60301 tggggcatcc tgtttatcgc agactcttag agaaaaagat tggcgatgta gctgtggagg
    60361 atttgaaagt tgaaagtgct gatggtgaag aaatacctgt ctcactcaat caagtctttc
    60421 cagaattggc agaactaggc agtcaagaag accttggtct caagaagaaa gtggccaatg
    60481 attttgactt ggaacatttt cgccagctga tggctcgaga tggacttcgt tttgcggatg
    60541 agcagtccga tgtcttaaac ctctttgcta ttgccgagga gaagaaatgg acttggtttg
    60601 aaacctatca attggccaag tcaacagctg tttctcaggt tatttcaacc aaacgcatgc
    60661 gtgaaaaaat tgctcaaaaa ccagtttcat ctgactttag tcttaaggaa acaaccatta
    60721 tcaaagaagc caaaagtaaa actgccctgc agttcttggc agaaatcaag caaacacgca
    60781 agggaaccat tacccaaaca gaaagagaac tcttgcaaca gatggctggc ttgggcttgc
    60841 tggacgaagt catcaatatc attcttttat tgacctttaa taaggtcgat tcggcaaata
    60901 tcaatgagaa atatgccatg aaggtagcca atgactatgc ctatcaaaag attcattcgg
    60961 cagaagaggc agtcttgcgc atccgtgagc gaggacagaa agcaaaaaca caaaaacaga
    61021 atcagactgc cccagtaaaa accaatgttc ctaaatggag taatcctgaa tataagaatg
    61081 aaaccagcga ggaaactcgt ctggaactag aacgtaagaa gcaagaacta ttagctcgat
    61141 tagaaaaagg aggagattag atggaaagtg tcggagacgt actcaaacgt caacccagcc
    61201 gtttttatta tcaagatttg gtccagaaaa tcatgaagga ccctgatgtt gcggctttta
    61261 tccagcaaga atccttgact ccagaggaat taaatcgcag tatctccaag tttaatcagt
    61321 acatcaccga gcgtgacaag tttctccgag gagatacaga ttatattgcc aaaggctaca
    61381 agcctatact agtcatgaac catggctatg cggatgtttc ttatgaagaa actcctgaac
    61441 taatcgcggc ggaaaaagaa gcggctatta agaaccgtct caagttaatc aatctaccag
    61501 ccagtctcaa gaaagctagt ttggctcaag ttgacttgga tgatttgggg cgcttaccag
    61561 tttttgaaaa gctactagcc ttcgtggagc aatatccagc tattcgaaaa ggtctttacc
    61621 tatatggaga ttttggtgtg ggtaaaagtt tcatggtggc tgccctagct catgatttat
    61681 cagaaaaacg tggtgtttca tccactctcc tccactatcc tagctttgtc attgatgtca
    61741 aaaatgctat cagtgatggc aatgttaaga ccttggtgga tgagattaag ctgtctgagg
    61801 tcctgatttt agatgatatt ggcgccgagc aatccaccgc ttgggtgcgt gacgaaatcc
    61861 tgcaggtcat tctccaatat cggatgcagg aaaatttacc gacctttttc acatccaact
    61921 tcaactttga agatttagag aagcattttg cgaaagtgaa acatggaaat gacgaaacct
    61981 gggaagccag acgcgtcatg gaacgcatcc gttatttggc tgaagagact cgtttagaag
    62041 gagtaaaccg tcgatgacag aaacaatcaa attaatgaag gctcatactt cagtgcgcag
    62101 gtttaaagag caagaaattc cccaagtaga cttaaatgag attttgacag cagcccagat
    62161 ggcatcatct tggaagaatt tccaatccta ctctgtgatt gtggtacgaa gtcaagagaa
    62221 gaaagatgcc ttgtatgaat tggtacctca agaagccatt cgccagtctg ctgttttcct
    62281 tctctttgtc ggagatttga accgagcaga aaagggagcc cgacttcata ccgacacctt
    62341 ccaaccccaa ggtgtggaag gtctcttgat tagttcggtc gatgcagctc ttgctggaca
    62401 aaacgccttg ttggcagctg aaagcttggg ctatggtggt gtgattatcg gtttggttcg
    62461 atacaagtct gaagaagtgg cagagctctt taacctacct gactacacct attctgtctt
    62521 tgggatggca ctgggtgtgc caaatcaaca tcatgatgtg aaactgagac tgccactaga
    62581 gaatgttgtc tttgaggaag aataccaaga acagtcaact gagacaatcc aagcttatga
    62641 ccgtgtgcag gctgactatg ctggggggcg tgcgaccaca agctggagtc agcgcctagc
    62701 agaacagttt ggtcaagctg aaccaagctc aactagaaaa aatcttgaac agaagaaatt
    62761 attgtagaaa gtgagaaatt atggccctac caactattgc cattgtagga cgtcccaatg
    62821 ttgggaaatc aaccctattt aatcggatcg ctggtgagcg aatctccatt gtagaagatg
    62881 tcgaaggagt gacacgtgac cgtatttatg caacgggtga gtggctcaat cgttctttta
    62941 gcatgattga tacaggagga attgatgatg tcgatgctcc tttcatggaa caaatcaagc
    63001 accaggcaga aattgccatg gaagaagcag atgttatcgt ctttgtcgtg tccggtaagg
    63061 aaggaattac cgatgcagac gaatacgtag cccgtaagct ttataagacc cacaaaccag
    63121 ttatcctcgc agttaacaag gtggacaacc ctgagatgcg aaatgatatc tatgatttct
    63181 atgccctcgg tttgggtgaa ccactgccta tctcatctgt ccatggtatc ggtacagggg
    63241 atgtgctaga tgcgatcgta gaaaatcttc caaatgaata tgaggaagaa aatccagatg
    63301 tcattaagtt tagcttgatt ggtcgtccta acgttggaaa atcaagcttg atcaatgcta
    63361 tcttgggaga agaccgtgtt attgctagtc ctgttgctgg aacaactcgt gatgccattg
    63421 atacccactt tacagataca gatggtcaag agtttaccat gattgatacg gctggtatgc
    63481 gtaagtctgg taaggtttat gaaaatactg agaaatactc tgttatgcgt gccatgcgtg
    63541 ctattgaccg ttcagatgtg gtcttgatgg tcatcaatgc ggaagaaggc attcgtgagt
    63601 acgacaagcg tatcgcagga tttgcccatg aagctggtaa agggatgatt atcgtggtca
    63661 acaagtggga tacgcttgaa aaagataacc acactatgaa aaactgggaa gaagatatcc
    63721 gtgagcagtt ccaatacctg ccttacgcac cgattatctt tgtatccgct ttgaccaagc
    63781 aacgtctcca caaacttcct gagatgatta agcaaatcag cgaaagtcaa aatacacgta
    63841 ttccatcagc tgtcttgaac gatgtcatca tggatgccat tgccatcaac ccaacaccga
    63901 cagacaaagg aaaacgtctc aagattttct atgcgaccca agtggcaacc aaaccaccaa
    63961 cctttgtcat ctttgtcaat gaagaagaac tcatgcactt ttcttacctg cgtttcttgg
    64021 aaaatcaaat ccgcaaggcc tttgtttttg agggaacacc gattcatctc atcgcaagaa
    64081 aacgcaaata aaaaagtaga atctggaatg acagttccgg atttttttga tataataaaa
    64141 taatagaaaa cgctatcaaa agaaggaggg tgatgtcggt gatggaacat ttgtttaaat
    64201 tcttactttt agcaccgtac ttttattttg ataactggat tgagaaggcc aacagaaata
    64261 gtaagttttt tccaattttt tattattttt actggtttta catccccttc tattctcttt
    64321 ttagccttgc ttggacagtt gtttcagttc tgtttttcaa taccgtcttg agaaatgtga
    64381 cagatatcaa gttatggggc atttggtttc tttttattct gctagctatt ggtatgaatt
    64441 ggttaactta ttcctgtttc aaagaaatgt ttcgcttgag acaggaacta gggaagtcta
    64501 agggtggaag gcattgattt atatcggttt ctatttgtag gaggtggctt atggtacctc
    64561 taaaatcatt tattacacgc tattccaagg tttatattgg taataacatt taatagaacg
    64621 aaactaaaga aaacaattta aaaaaggagg cttgtgatgg aacacttgtt taaaatgata
    64681 atcttattac cctgttttta ctttttcagc tggattgaca aggataatag agaaagtaaa
    64741 tttttcccaa ttttttacta tttttactgg atttacatca ccctctatgc tctttttagc
    64801 cttgcttgga cagttttttc agttctgttt ttcaatatcg tcttgagaaa tttgacagat
    64861 atcaagttat ggggtatttg gctattatta ctacttatcg cttttgctag tgactggtta
    64921 gactatatct gtttcaaaaa aatgcttgac ttgagacggg aactagggaa gtctaaaggc
    64981 gtaaggcatt gatttatact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgga
    65041 ttatatatgt aactgacttc gtcagtctta tctacaacct caaagcagtg ctttgagcaa
    65101 cttgcggcta gtttcctagt ttgctctttg attttcattg agtattatat tactttctat
    65161 ttgtaggagg tggcttatga agattcctct cttaactttg gcaaggcata aatttgttta
    65221 tgtcttgctt actttgcttt ttcttgcttt ggtttatcgt gatgttttga tgacttattt
    65281 cttttttgat attcatgcgc ccgatctagc taaattcgat ggacaagcaa ttaaaaatga
    65341 cttattaaaa tcagcattag attttcgtat tctccagttc aatctaggtt tttatcaatc
    65401 atttattatt ccaatcatca ttgttttgct aggttttcaa tatattgagc tgaaaaataa
    65461 agttttacga ttgagtattg gaagagaagt gagttatcaa gggttaaaaa gaaagttgac
    65521 tttgcaagtt gcaagtatcc cttgtttgat atatttagtg actgtgctga taattgcaat
    65581 tataacctat ttctttggga ctttttctcc tcttggatgg aattctctat tttctgatgg
    65641 aagtggttta caaagactcc tagatggaga gataaaaagc tatttgttct ttacttgtgt
    65701 cctactaatc ggtattttca tcaatgcaat ctatttttta caaatagttg attatgtggg
    65761 gaatgtgact cgttcggcaa tcacctattt gatgtttctt tggcttggtt ctatgctgct
    65821 ctatagtgcc ttgccttact atatggttcc tatgacgagt ttgatgcaag ctagctatgg
    65881 ggatgtaagt ttgatgaaac tctttactcc ttatatcctt tatattgtcc cttatatggt
    65941 gcttgaaaaa tatgaagata atgtttaaga attttaacaa tatttggcta aagagaaaga
    66001 tcgttttact acttcgtata gttctgatga tgattttgat aaactatcta ttgtcaacag
    66061 cggttcaaaa gcaggatgct gttatctttt tcaagagaga attgatttca atcttttcct
    66121 ataatgacta ttctgaagcg aatttagaaa tccccaaact cttgttaaac ctttcgcttt
    66181 tcatggtagg atggctctct gtcattttac ttgaaagtga tttggcagac cattaccatc
    66241 acttgattcg ctatcaatca agctcctttt tcgattatac aaggaaacga ttggttgtca
    66301 tttctaaatt ttttactcaa gatttacttg tctggttcct tggtttactt ccgctaggaa
    66361 ttcatttcaa aacagtcgca cttttctttt tacttgctca gttaatgatg ttgtacttac
    66421 tactgtctta tctgatagca ctgattagtg cgggcgctgg tttttccttt tttctctatt
    66481 ttttagcatt tgtgggacaa gaatggatga tggatcatat tgtaacagtg tatttactac
    66541 tcttaagttt attagttatg ttgattctta gtcgcttgga agagaaattt aagaaaggat
    66601 aaacgatgag acttgaaatt ataaatggac agaaaattta tgggaaaaga cctattttaa
    66661 atcagttgaa tttggtgttt caatcaggaa aaatttatgg acttaaaggt gataatggat
    66721 ctggcaagac ggttctttta aaggtacttg ctggttatat taagcttgac aaaggaaaag
    66781 ttcttcaaga cgggaaagtc tacgggataa aaaatcatta tattcaggat gcaggaattt
    66841 taattgaaaa agtcgagttt ttatctcatt tatccctgag agaaaatttg gaactgttaa
    66901 ggtatttttc atctaaagtt acggaaaaaa gaattgccta ttggattcaa tactatgatt
    66961 tacaggaatt tgaagacgtt gaataccggc atttatcctt gggaacaaag caaaaaatgg
    67021 ccttgattca agcctttatt tcctctcctt ctatactctt tctcgatgaa cctatgaatg
    67081 ctttggatga gaaaagtgtg aggttaacca aacaggtcat tttatcttac ctgaaaaaag
    67141 aaaatggtct ggttatcctg acgtcgcaca tatcggaaga tatttcagac ctttgtacag
    67201 atgtattagt tgtcgaaaat ggacatatac aatatgtaaa ggatatacaa tcctaggaga
    67261 tggcttatgg cacatctaaa atcatttatt acacgctatt ccaaggttta tattggttta
    67321 gttctgctga tctggctgtc tttcttcttt atcccttggg atagagcgat tctgggggta
    67381 aggattgaca tcttcatcat acagaaagtc ttgctagttt ttggaattct gtccattttg
    67441 atggccttgc tgtccaagaa agtcagtctc tttgtttttg gactgatttg ctgtctttct
    67501 ctttggatta acttatttat cacatttgcc attttgccaa tttttggcaa ttaaacagtc
    67561 ataaaagtcg gagaggttag cttgaaaact aacctctttt tccttttcaa aatggggatt
    67621 cttccttgaa aataatcagt aattgtgcta aaattaaagg aacattctaa aatattcgga
    67681 atttaaagta aggaaaaaca tggctaatat tttaaaaaca attatcgaaa atgataaagg
    67741 agaaatccgt cgtctggaaa agatggctga caaggttttc aaatacgaag accaaatggc
    67801 tgctttgact gacgaccaac taaaagcaaa aacagttgaa tttaaggaac gttatcaaaa
    67861 tggagaatca ctggattcat tgctttacga agcatttgcg gttgtccgtg aaggtgccaa
    67921 acgtgtccta ggtctcttcc cttataaggt tcaggtcatg ggggggattg ttcttcacca
    67981 tggtgacgtg ccagagatgc gtacagggga agggaaaacc ttgactgcga ccatgccggt
    68041 atacctcaat gccctttcag gtaaaggggt tcacgtagtt acggttaatg aatacctgtc
    68101 agaacgtgac gcgactgaga tgggtgaatt gtactcttgg cttggtttgt cagtagggat
    68161 taacttggct accaaatctc caatggagaa aaaagaagcc tatgagtgtg atattactta
    68221 ctcaactaac tcagaaatcg gatttgacta ccttcgtgac aatatggtcg ttcgcgctga
    68281 aaacatggta caacgtccgc ttaactatgc cttggtcgat gaggttgact ctatcttgat
    68341 tgacgaggct cgtacacctt tgattgtatc aggtgccaat gcggttgaaa ccagtcagtt
    68401 gtatcacatg gcagaccact atgtaaaatc tttgaacaaa gatgactaca tcatcgatgt
    68461 gcagtctaag actattggtt tgtctgattc agggattgac agggctgaaa gctacttcaa
    68521 acttgaaaac ctctatgaca tcgaaaacgt ggctttgacc cactttatcg ataacgccct
    68581 tcgtgccaac tacatcatgc ttctcgatat tgactatgtg gtgagcgaag agcaagaaat
    68641 cttgattgtc gaccaattta caggtcgtac catggaaggt cgtcgttatt ctgatggatt
    68701 gcaccaagct attgaagcca aagaaggtgt gccaatccag gatgaaacca agacatctgc
    68761 ctcaatcacg taccaaaacc ttttccgtat gtacaaaaaa ttgtctggta tgacgggtac
    68821 aggtaagact gaggaagaag aatttcgtga aatctacaac attcgtgtta ttccaatccc
    68881 aacaaaccgt cctgttcaac gtattgacca ctcagacctt ctttatgcaa gtatcgaatc
    68941 taagtttaaa gcggttgtcg aagacgttaa ggctcgttac caaaagggtc aacctgtctt
    69001 ggttggtaca gtagcggttg aaactagtga ctacatttct aagaaattgg ttgcagctgg
    69061 tgttcctcac gaagtcttga atgccaaaaa ccactataga gaagcccaaa tcatcatgaa
    69121 tgctggtcaa cgtggtgccg ttaccatcgc aaccaacatg gcgggtcgtg gtaccgacat
    69181 caagcttggt gaaggtgttc gtgaacttgg aggactttgt gttattggta cagaacgtca
    69241 tgaaagtcgt cgtatcgata accagcttcg tggacgttca ggtcgtcaag gagatccagg
    69301 tgagtcacaa ttctacctat ctcttgaaga tgatttgatg aaacgttttg gttctgaacg
    69361 cttgaaggga atctttgaac gcttgaacat gtctgaagag gcgattgagt ctcgcatgtt
    69421 gacgcgtcag gttgaagcag cgcaaaaacg tgtcgaagga aataactacg atacccgtaa
    69481 acaagtcctt caatacgacg atgtcatgcg tgaacaacgt gagattatct atactcaacg
    69541 ttatgatgtc attactgcag accgtgactt ggcacctgaa attcaggcaa tgatcaaacg
    69601 cacgattggt cgtgtcgttg acggtcatgc gcgtgctaaa caagatgaga aactagaggc
    69661 aattttgaac ttcgctaagt acaacttgct tcctgaagat tctattacga tggaagactt
    69721 gtcaggcttg tctgataagg ccatcaagga agagcttttc caacgtgcct tgaaggttta
    69781 cgatagtcag gtttcaaaac tacgcgatga agaagcagtt aaagaattcc aaaaagtttt
    69841 gattctacga gtggtggata acaagtggac agatcatatc gatgcccttg atcaattgcg
    69901 taacgcggtt ggacttcgtg gctatgctca gaacaaccct gttgttgagt atcaggcaga
    69961 aggtttccgt atgtttaatg atatgattgg ttcgattgag tttgatgtga cacgcttgat
    70021 gatgaaagca caaattcatg aacaagaaag accacaggca gaacgtcata tcagtacaac
    70081 agcgactcgc aatatcgctg ctcaccaagc aagtatgcca gaagatttgg atttgagcca
    70141 gattggacgc aatgaacttt gcccatgtgg ttctggtaag aaatttaaaa actgtcacgg
    70201 taaaagacaa taaaatgaga tagtttagag gcggatatct tgtgaaaagt aaatttttac
    70261 tgggtatccg tttgctttat aaggagatga gttatggtat ttacagcaaa aagctctaaa
    70321 ataaatatag aagaagttcg tgccttgtca aaattagaag gtcaggcttt ggagaggaaa
    70381 tcacagcgag atcaagagct agaagccatt atacgtggag aagaccagcg aattctcttg
    70441 gtaatcgggc catgctcatc tgacaacgaa gaagctgtcc ttgaatacgc taagcgtttg
    70501 gcagtcctac aagaagaagt ggcagatcgt atctttatgg ttatgcgtgt ttatactgcc
    70561 aaaccccgta ccaacggaga tggctataag ggcttgattc accagcctaa cgcgacagaa
    70621 gcgcctagtc ttatcaatgg aatcaaagcc gttcgccatc ttcactatcg tgtcatcaca
    70681 gaaacaggga tgacaactgc tgatgaaatg ctttatcctg aaaaccttcc gcttgtagat
    70741 gatttgattt cttacatggc agttggtgcc cgttcagttg aagaccagca acaccgcttt
    70801 gtggcaagtg gggcaggatt ttctactggt tttaaaaatc caacctctgg aaatctcaat
    70861 gtcatgttta atgggattta tgctgctcaa aacaaacaaa gtttcctttt cttaggaaaa
    70921 gaagtagaaa caactgggaa cccgctttca cacgctattc ttcgtggtgc tcttaatgag
    70981 tatggaaaaa atattcccaa ctactattat gacaatttaa ttgataccat tgcccagtat
    71041 gagaaaatgg gcttggaaaa tccttttatc atcattgata ccaatcatga caattctggt
    71101 aagcagtata ttgaacagat ccgaattgtc cgccaggcct tgattaaccg tgcttggaat
    71161 gaaaaaatta agcagttcgt tcgtggtttt atgattgagt cttatctgga agatggtcga
    71221 caaaatgagc cagaagtatt tggtaagtct atcacagacc cttgcctggg ttgggataac
    71281 acagaagctc ttgtcagaga aatttacaaa acgttaggag aataagatgg catttattga
    71341 aaaaggtcaa gaaatcgata tggaagtcat caaggctgaa acccaattgt ctgcggaagc
    71401 cttgagactc aaggaaagcc gtgacaggga attggcagat attatttcag gggaagatga
    71461 ccgtattctc ttggtgattg gtccttgctc ttctgataat gaagaggcgg tcttggaata
    71521 tgctcgccgt ttatccgcct tgcaaaagaa ggtagcggat aagattttca tggtcatgcg
    71581 cgtgtatact gctaagcctc gtaccaatgg agacggctat aaaggattgg ttcaccagcc
    71641 agatacttct aaggctccaa gcctgattaa cggcttgcag gctgtgcgcc agttgcacta
    71701 ccgcgtgatt acagagactg gtttgacaac ggcagatgag atgctttatc cgtcaaatct
    71761 gatcttggtg gatgacttgg tcagctacca tgccgttgga gctcgttctg tggaagacca
    71821 agagcaccgc tttgtggctt ctgggattga tgcaccagta gggatgaaaa atccaacctc
    71881 aggaaatttg ggtgttatgt ttaacgccat ctatgctgct caaaacaagc aaaccttcct
    71941 ttatcatggg caggaagttg agacatcagg taatcctttg gcccatgtta tcctccgtgg
    72001 agcagtcaac gagtatggca attatatgcc gaattactac tatgaaaacc tactccaagc
    72061 cattgaacgc tatgaaacca tgggacttga aaatcctttt atcctcattg acaccaacca
    72121 tgataactca ggcaagcaat atatggagca gattcgaatt gttcgccaga ccttgcagaa
    72181 tcgtgattgg aatgagaaaa ttaaaaagac ggttcgagga tttatgattg aatcttacct
    72241 agcagatggt cgtcaaaacc aaccagagat ctttggttgc tctattactg acccttgcct
    72301 aggttgggaa aatacagagg ccttggtaga agagatttat gttaccttga caaaataagt
    72361 gaaaaggatg gagttgggga atctcaactc cttttgatga gaatgatagt tggacacgga
    72421 attgacatcg aagaattggc ttcgatagaa agcgcagtta cacgacatga aggatttgct
    72481 aagcgtgtac tgaccgctca ggaaatggag cgcttcacca gtctcaaagg acgcaggcaa
    72541 atagaatatt tagctggtcg ctggtcggct aaggaggcct tttccaaggc tatgggaacg
    72601 ggcattagca agctcggttt tcaggatttg gaagtcttga acaatgaacg tggggcgcct
    72661 tattttagtc gggcaccatt ttcaggaaag atttggctgt ctatcagcca caccgatcag
    72721 tttgtgacag ccagtgtcat tttggaggaa aatcatgaaa gctagtccac atagaccaac
    72781 caaggctctg attcatctgg gagctattcg acaaaatatt cagcaaatgg gggctcatat
    72841 ccctcaagga acgctcaagt tggctgtggt taaggccaat gcttatggtc atggagctgt
    72901 tgccgttgcc aaggcaattc aagatgatgt tgatggcttt tgcgtttcca atatcgatga
    72961 agccattgaa ctcagacaag ctggactcag caagccaatc ctcattttag gagtttctga
    73021 aatcgaagct gttgctctag ctaaagaata tgacttcacc ttgacagtgg ctggactgga
    73081 gtggattcaa gcactcttag ataaggaagt ggacctaact ggattgacag tccacctcaa
    73141 gattgattca ggaatgggac ggattggttt tagagaggcc agtgaggttg agcaggctca
    73201 agatttgctc caacaacacg gtgtttgtgt tgaaggaatc tttacccact ttgctactgc
    73261 tgatgaggaa tcagatgact attttaatgc ccagttagaa cggtttaaaa ctattttagc
    73321 tagtatgaag gaagttccag agctggttca tgctagcaat tctgcaacga ctctttggca
    73381 tgtagagact attttcaatg cggttcgtat gggagatgcc atgtatggcc tcaatccaag
    73441 tggagcggtc ttggatttgc cttatgattt gataccggcc ttgaccttgg agtctgctct
    73501 ggttcatgtc aagacagttc cagctggagc ttgcatgggc tatggagcaa cttatcaagc
    73561 ggatagcgag caagtcatcg cgaccgtgcc aatcgggtat gcagatggat ggacaagaga
    73621 catgcaaaat ttctctgtct tggtagatgg ccaagcttgc ccaattgtcg gcagggtttc
    73681 gatggaccaa atcactattc gattgcctaa gccttaccca ctcggaacca aggtaacctt
    73741 gattggctcc aatggggata aggaaatcac tgcaactcag gtagcgacct accgcgtaac
    73801 cattaactat gaggtggttt gcctcctcag cgaccgtatt ccgagagaat attattagaa
    73861 aagaaaggag tggagcatga atctacatca acccttgcat gtcttgcctg gtgtgggacc
    73921 aaagtcagca gaaaaatacg ccaaactagg aattgaaaac ttgcaagatc tcttgctcta
    73981 ctttcctttc cgttatgaag acttcaaaac caagcaggtg ctggagctgg aagacggtga
    74041 gaaggcagtt ctttctggtc aggtagtgac tcctgctagt gtccagtatt atggtttcaa
    74101 gcgcaatcgc ctgcgtttta gtctcaagca gggagaggtc gtttttgcgg tgaatttctt
    74161 taaccagccc tatctggctg ataaaataga gttgggagca acccttgctg tctttggaaa
    74221 atgggaccgc gctaaggcta gtctgaatgg gatgaaggtt ctggctcagg tagaagatga
    74281 cctccagcct gtttatcgtc tggctcaggg aatcagtcag gccagtctgg ttaaggtcat
    74341 caagacggct tttgatcagg gactggacct cttgatagaa gaaaatctgc cccagtcttt
    74401 actagacaaa tacaaactca tgtcccgttg tcaggcagtc cgagctatgc attttccaaa
    74461 ggatttggca gaatacaagc aggctcttcg ccgtataaag tttgaggaac tcttttattt
    74521 ccaaatgcag ctgcagatgc tcaagtctga aaatagagtt cagggaagtg gtctggttct
    74581 gaattggtct caggaaaaag tgacagcagt taaagtaagt cttccttttg ccctgaccca
    74641 agctcaggaa aagagtttgc aggaaatttt aactgatatg aagtccgacc accacatgaa
    74701 tcgtctccta caaggggatg tggggagtgg aaaaacggta gtcgctggct tggccatgtt
    74761 tgcggcagtg acagcaggtt atcaggctgc cctaatggta ccaacagaaa tcctcgcaga
    74821 gcaacacttt gagagtttac agaacctttt tcccaatttg aaactggctc tcttgacagg
    74881 ttccttgaaa gctgcagaaa agagagaggt cttggagacc attgccaagg gtgaggctga
    74941 tttgattata ggaactcacg ctctgataca agatggggtg gagtatgctc gtcttggttt
    75001 gattattatc gatgagcagc accgttttgg tgtagggcaa aggcgtattt tacgggaaaa
    75061 aggtgacaat ccagatgtcc tcatgatgac ggcgactccc attccacgga cgcttgccat
    75121 cacagccttt ggagatatgg atgtttccat tatcgaccag atgccagcag gtcggaagcc
    75181 tattgtgacg cgctggatca aacatgagca actacctcag gtcttgactt ggttagaggg
    75241 ggaaattcaa aaaggttccc aagtctatgt catctctcct ttgattgaag aatcagaagc
    75301 tctagatttg aaaaatgcca ttgccttatc agaggagttg acgactcatt ttgcaggcaa
    75361 ggcagaggtg gctcttctac atggtaggat gaagagtgac gaaaaagacc agatcatgca
    75421 ggatttcaag gagagagaga cggatattct ggtttcgacg acggttattg aggttggggt
    75481 caacgttccc aatgcgactg tcatgattat catggatgcc gatcgcttcg gtctcagtca
    75541 acttcaccag cttagaggtc gtgtcggtcg gggggacaag cagtcctacg ctgttctcgt
    75601 tgccaatccc aagacggatt ctgggaaaga ccgcatgcgc atcatgatag aaacgaccaa
    75661 tggatttgtc cttgcggagg aagatttgaa aatgcgtggt tctggtgaga tttttggaac
    75721 cagacagtca ggacttccag agttccaagt ggctgatatt atcgaagatt ttccgatttt
    75781 agaagaagca agaaaggttg ctagctacat tagttctata gaagtttggc aagaagatcc
    75841 agagtggcgc atgattgccc ttcatctgga aaagaaagaa catctggatt aagctttctc
    75901 taaggaaaac ttaagctagt ttttaggttt ggctcttata ctaaagtcat caaaaagaaa
    75961 cgaggactct catatgacag taacgattaa agtaaattac caaaccactt tccaaaagaa
    76021 ggaagcaaaa aactagtata aacagaagag agagcgaaat gctctttttc gtttctaaaa
    76081 ctactttcag cccatcatcc taaaagtaaa gaatctaaat tcactttcta tttatccttc
    76141 tttcttgcat tgattacata gatatgctac agttgtggta acgattacaa aataaaagga
    76201 gcatgctatg aaaaatccag ctttgctaga agaaattaag acctatagag gaagggatga
    76261 ggttccggaa gactttgatg ctttctggga tggggaagtg aaaaatgttt ccacacctcc
    76321 atcctaccac ttggaggaaa gagatttcca cattcctcaa gtcaagtgct atgagttaac
    76381 atttgaagga agcaaggaag gaaaggtcta tgcacgcatt gttcttccaa agagtgagga
    76441 gaaggttcca ctaatcttcc attttcatgg ttatatggga cgtggctggg actgggccga
    76501 catgctgggc ttcaccgtag ctggttacgg tgttgtttcc atggatgtgc ggggccagtc
    76561 aggttactca caagacggct tgcgttctcc tttaggaaat accgtgaagg ggcatattat
    76621 ccgtggtgct atggaaggtc gggaccacct cttttataag gatgtttatc tggatattta
    76681 ccagttggtc gaaattgttg ctagtctgtc tcaggttgat gagaagcgtc tttctagcta
    76741 tggtgcctca caaggagggg ctctagctct agttgcagca gcgctcaatc ctcgaattca
    76801 gaaaacagtt gccatttatc ccttcttgtc agacttcaga cgggtgattg agattggtaa
    76861 tactagcgag gcttacgacg aacttttccg ttatttcaag tttcacgacc ccttccatga
    76921 aacagaggag gaaatcatgg cgacccttgc ctatatcgat gtcaaaaatc ttgcccatcg
    76981 tatccaaggt gaggttaaga tgattacggg cttggacgac gatgtttgct atcccattac
    77041 ccagtttgcg atttataatc gtctgacctg cgataaaacc tatcgtatca tgcctgagta
    77101 tgctcacgaa gccatgaatg tatttgtcaa tgaccaagtc tacaactggc tctgtggaag
    77161 tgagattcct tttaaatatt taaaataagg agtcgactct aagcacaaaa tcttaaaaat
    77221 tacaaacacg catagtatca ggggcttaag aaaacttgat actatgcgtt ttatcatgga
    77281 aatatagtaa aatgaaacaa gaacaggaca aattgatcag gacagtcaaa tcgatttcta
    77341 acaatgtttt agaagcaaat gtgtactatt ctagtttcaa tctattatat ttatagaatt
    77401 ttttgttgct agatttgtca aattgcttaa aataattttt ttcagaaagc aaaagccgat
    77461 acctatcgag tagggtagtt cttgctatcg tcaggcttgt ctgtaggtgt taatactttt
    77521 caaaaatctc tttaaaccac gtcagcttcg ccttgccgta tatatgtt
//
LOCUS       DAVMCN010000004        65747 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVMCN010000004 DAVMCN010000000
VERSION     DAVMCN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.004"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..428
                     /locus_tag="VYP85_000345"
     CDS             <1..428
                     /locus_tag="VYP85_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV1880905.1"
                     /translation="LENLLENEYSRLNATPTNLELSWCEGTSGILLYFELLYDKRYSN
                     IISRFQQLAFKFNLIQSSCYCHGLSSLLQTLNYQDKLNLRENVIEILLSRSKRDKNGI
                     LVFECEESSDTLFDFGIGNLGIYWSILGERFPFELKKEL"
     gene            428..1654
                     /locus_tag="VYP85_000346"
     CDS             428..1654
                     /locus_tag="VYP85_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1880906.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            2102..2758
                     /locus_tag="VYP85_000347"
     CDS             2102..2758
                     /locus_tag="VYP85_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1880907.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            2748..3071
                     /locus_tag="VYP85_000348"
     CDS             2748..3071
                     /locus_tag="VYP85_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1880908.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            3175..4005
                     /locus_tag="VYP85_000349"
     CDS             3175..4005
                     /locus_tag="VYP85_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1880909.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            4159..5013
                     /locus_tag="VYP85_000350"
     CDS             4159..5013
                     /locus_tag="VYP85_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1880910.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            5113..6486
                     /locus_tag="VYP85_000351"
     CDS             5113..6486
                     /locus_tag="VYP85_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1880911.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            6479..7540
                     /locus_tag="VYP85_000352"
     CDS             6479..7540
                     /locus_tag="VYP85_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1880912.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            7542..8234
                     /locus_tag="VYP85_000353"
     CDS             7542..8234
                     /locus_tag="VYP85_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1880913.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(8264..8833)
                     /locus_tag="VYP85_000354"
     CDS             complement(8264..8833)
                     /locus_tag="VYP85_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1880914.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            8968..9582
                     /locus_tag="VYP85_000355"
     CDS             8968..9582
                     /locus_tag="VYP85_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1880915.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            9584..11230
                     /locus_tag="VYP85_000356"
     CDS             9584..11230
                     /locus_tag="VYP85_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1880916.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            11242..12528
                     /locus_tag="VYP85_000357"
     CDS             11242..12528
                     /locus_tag="VYP85_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1880917.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            12580..13113
                     /locus_tag="VYP85_000358"
     CDS             12580..13113
                     /locus_tag="VYP85_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1880918.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            13191..13661
                     /gene="nrdI"
                     /locus_tag="VYP85_000359"
     CDS             13191..13661
                     /gene="nrdI"
                     /locus_tag="VYP85_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1880919.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(13954..15216)
                     /locus_tag="VYP85_000360"
     CDS             complement(13954..15216)
                     /locus_tag="VYP85_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1880920.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDAVFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(15526..15984)
                     /locus_tag="VYP85_000361"
     CDS             complement(15526..15984)
                     /locus_tag="VYP85_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1880921.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(15981..16421)
                     /locus_tag="VYP85_000362"
     CDS             complement(15981..16421)
                     /locus_tag="VYP85_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1880922.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            16777..18726
                     /gene="mutL"
                     /locus_tag="VYP85_000363"
     CDS             16777..18726
                     /gene="mutL"
                     /locus_tag="VYP85_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1880923.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(19051..19518)
                     /locus_tag="VYP85_000364"
     CDS             complement(19051..19518)
                     /locus_tag="VYP85_000364"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1880924.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(19519..20724)
                     /locus_tag="VYP85_000365"
     CDS             complement(19519..20724)
                     /locus_tag="VYP85_000365"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1880925.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRIDDLIQFSKKHNIPLITIKELQEYRKAYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKIIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(20744..21379)
                     /gene="ribE"
                     /locus_tag="VYP85_000366"
     CDS             complement(20744..21379)
                     /gene="ribE"
                     /locus_tag="VYP85_000366"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1880926.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(21364..22464)
                     /gene="ribD"
                     /locus_tag="VYP85_000367"
     CDS             complement(21364..22464)
                     /gene="ribD"
                     /locus_tag="VYP85_000367"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1880927.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMTMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(22598..22712)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            22869..23462
                     /gene="ruvA"
                     /locus_tag="VYP85_000368"
     CDS             22869..23462
                     /gene="ruvA"
                     /locus_tag="VYP85_000368"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1880928.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            23472..24035
                     /locus_tag="VYP85_000369"
     CDS             23472..24035
                     /locus_tag="VYP85_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1880929.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            24032..24709
                     /locus_tag="VYP85_000370"
     CDS             24032..24709
                     /locus_tag="VYP85_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1880930.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(24846..25877)
                     /locus_tag="VYP85_000371"
     CDS             complement(24846..25877)
                     /locus_tag="VYP85_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1880931.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(26132..26815)
                     /locus_tag="VYP85_000372"
     CDS             complement(26132..26815)
                     /locus_tag="VYP85_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1880932.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(26827..27771)
                     /locus_tag="VYP85_000373"
     CDS             complement(26827..27771)
                     /locus_tag="VYP85_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1880933.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            27903..30734
                     /gene="uvrA"
                     /locus_tag="VYP85_000374"
     CDS             27903..30734
                     /gene="uvrA"
                     /locus_tag="VYP85_000374"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1880934.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQVLSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            30727..31788
                     /locus_tag="VYP85_000375"
     CDS             30727..31788
                     /locus_tag="VYP85_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1880935.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            31920..32318
                     /gene="spx"
                     /locus_tag="VYP85_000376"
     CDS             31920..32318
                     /gene="spx"
                     /locus_tag="VYP85_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1880936.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            32384..32953
                     /locus_tag="VYP85_000377"
     CDS             32384..32953
                     /locus_tag="VYP85_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1880937.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            33040..33306
                     /locus_tag="VYP85_000378"
     CDS             33040..33306
                     /locus_tag="VYP85_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1880938.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            33310..33729
                     /gene="ruvX"
                     /locus_tag="VYP85_000379"
     CDS             33310..33729
                     /gene="ruvX"
                     /locus_tag="VYP85_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1880939.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            33745..34050
                     /locus_tag="VYP85_000380"
     CDS             33745..34050
                     /locus_tag="VYP85_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1880940.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            34357..35607
                     /locus_tag="VYP85_000381"
     CDS             34357..35607
                     /locus_tag="VYP85_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1880941.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            35604..36161
                     /locus_tag="VYP85_000382"
     CDS             35604..36161
                     /locus_tag="VYP85_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1880942.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            36307..37839
                     /gene="cls"
                     /locus_tag="VYP85_000383"
     CDS             36307..37839
                     /gene="cls"
                     /locus_tag="VYP85_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1880943.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            38097..39635
                     /locus_tag="VYP85_000384"
     CDS             38097..39635
                     /locus_tag="VYP85_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1880944.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            39755..41962
                     /gene="nrdD"
                     /locus_tag="VYP85_000385"
     CDS             39755..41962
                     /gene="nrdD"
                     /locus_tag="VYP85_000385"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1880945.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            41974..42114
                     /locus_tag="VYP85_000386"
     CDS             41974..42114
                     /locus_tag="VYP85_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880946.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            42158..42664
                     /locus_tag="VYP85_000387"
     CDS             42158..42664
                     /locus_tag="VYP85_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1880947.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            42657..43247
                     /gene="nrdG"
                     /locus_tag="VYP85_000388"
     CDS             42657..43247
                     /gene="nrdG"
                     /locus_tag="VYP85_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1880948.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            43244..43861
                     /locus_tag="VYP85_000389"
     CDS             43244..43861
                     /locus_tag="VYP85_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1880949.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            44127..44435
                     /gene="rpsJ"
                     /locus_tag="VYP85_000390"
     CDS             44127..44435
                     /gene="rpsJ"
                     /locus_tag="VYP85_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1880950.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            44652..45278
                     /gene="rplC"
                     /locus_tag="VYP85_000391"
     CDS             44652..45278
                     /gene="rplC"
                     /locus_tag="VYP85_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1880951.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            45303..45926
                     /gene="rplD"
                     /locus_tag="VYP85_000392"
     CDS             45303..45926
                     /gene="rplD"
                     /locus_tag="VYP85_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1880952.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            45926..46222
                     /locus_tag="VYP85_000393"
     CDS             45926..46222
                     /locus_tag="VYP85_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1880953.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            46240..47073
                     /gene="rplB"
                     /locus_tag="VYP85_000394"
     CDS             46240..47073
                     /gene="rplB"
                     /locus_tag="VYP85_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1880954.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            47177..47458
                     /gene="rpsS"
                     /locus_tag="VYP85_000395"
     CDS             47177..47458
                     /gene="rpsS"
                     /locus_tag="VYP85_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1880955.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            47470..47814
                     /gene="rplV"
                     /locus_tag="VYP85_000396"
     CDS             47470..47814
                     /gene="rplV"
                     /locus_tag="VYP85_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1880956.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            47827..48480
                     /gene="rpsC"
                     /locus_tag="VYP85_000397"
     CDS             47827..48480
                     /gene="rpsC"
                     /locus_tag="VYP85_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1880957.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            48484..48897
                     /gene="rplP"
                     /locus_tag="VYP85_000398"
     CDS             48484..48897
                     /gene="rplP"
                     /locus_tag="VYP85_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1880958.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            48907..49113
                     /locus_tag="VYP85_000399"
     CDS             48907..49113
                     /locus_tag="VYP85_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1880959.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            49138..49398
                     /gene="rpsQ"
                     /locus_tag="VYP85_000400"
     CDS             49138..49398
                     /gene="rpsQ"
                     /locus_tag="VYP85_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1880960.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            49424..49792
                     /gene="rplN"
                     /locus_tag="VYP85_000401"
     CDS             49424..49792
                     /gene="rplN"
                     /locus_tag="VYP85_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1880961.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            49870..50175
                     /gene="rplX"
                     /locus_tag="VYP85_000402"
     CDS             49870..50175
                     /gene="rplX"
                     /locus_tag="VYP85_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1880962.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            50199..50741
                     /gene="rplE"
                     /locus_tag="VYP85_000403"
     CDS             50199..50741
                     /gene="rplE"
                     /locus_tag="VYP85_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1880963.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            50759..51028
                     /gene="rpsN"
                     /locus_tag="VYP85_000404"
     CDS             50759..51028
                     /gene="rpsN"
                     /locus_tag="VYP85_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1880964.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            51313..51711
                     /gene="rpsH"
                     /locus_tag="VYP85_000405"
     CDS             51313..51711
                     /gene="rpsH"
                     /locus_tag="VYP85_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1880965.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            51903..52439
                     /gene="rplF"
                     /locus_tag="VYP85_000406"
     CDS             51903..52439
                     /gene="rplF"
                     /locus_tag="VYP85_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1880966.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            52523..52879
                     /gene="rplR"
                     /locus_tag="VYP85_000407"
     CDS             52523..52879
                     /gene="rplR"
                     /locus_tag="VYP85_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1880967.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            52897..53391
                     /gene="rpsE"
                     /locus_tag="VYP85_000408"
     CDS             52897..53391
                     /gene="rpsE"
                     /locus_tag="VYP85_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1880968.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            53363..53587
                     /gene="rpmD"
                     /locus_tag="VYP85_000409"
     CDS             53363..53587
                     /gene="rpmD"
                     /locus_tag="VYP85_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1880969.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            53732..54172
                     /gene="rplO"
                     /locus_tag="VYP85_000410"
     CDS             53732..54172
                     /gene="rplO"
                     /locus_tag="VYP85_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1880970.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            54185..55495
                     /gene="secY"
                     /locus_tag="VYP85_000411"
     CDS             54185..55495
                     /gene="secY"
                     /locus_tag="VYP85_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1880971.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            55646..56284
                     /locus_tag="VYP85_000412"
     CDS             55646..56284
                     /locus_tag="VYP85_000412"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1880972.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            56401..56619
                     /gene="infA"
                     /locus_tag="VYP85_000413"
     CDS             56401..56619
                     /gene="infA"
                     /locus_tag="VYP85_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1880973.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            56644..56760
                     /gene="rpmJ"
                     /locus_tag="VYP85_000414"
     CDS             56644..56760
                     /gene="rpmJ"
                     /locus_tag="VYP85_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1880974.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            56778..57143
                     /gene="rpsM"
                     /locus_tag="VYP85_000415"
     CDS             56778..57143
                     /gene="rpsM"
                     /locus_tag="VYP85_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1880975.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            57161..57544
                     /gene="rpsK"
                     /locus_tag="VYP85_000416"
     CDS             57161..57544
                     /gene="rpsK"
                     /locus_tag="VYP85_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1880976.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57587..58522
                     /locus_tag="VYP85_000417"
     CDS             57587..58522
                     /locus_tag="VYP85_000417"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1880977.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            58534..58920
                     /gene="rplQ"
                     /locus_tag="VYP85_000418"
     CDS             58534..58920
                     /gene="rplQ"
                     /locus_tag="VYP85_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1880978.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            59185..59451
                     /locus_tag="VYP85_000419"
     CDS             59185..59451
                     /locus_tag="VYP85_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1880979.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            59461..60798
                     /locus_tag="VYP85_000420"
     CDS             59461..60798
                     /locus_tag="VYP85_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1880980.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            61042..61734
                     /locus_tag="VYP85_000421"
     CDS             61042..61734
                     /locus_tag="VYP85_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1880981.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(61837..63472)
                     /locus_tag="VYP85_000422"
                     /pseudo
     CDS             complement(61837..63472)
                     /locus_tag="VYP85_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(63462..64553)
                     /locus_tag="VYP85_000423"
     CDS             complement(63462..64553)
                     /locus_tag="VYP85_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1880982.1"
                     /translation="MSEIKIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPTNEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKDNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(64566..65687)
                     /locus_tag="VYP85_000424"
                     /pseudo
     CDS             complement(64566..65687)
                     /locus_tag="VYP85_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        19617 a        12343 c        14476 g        19311 t
ORIGIN      
        1 tgttagaaaa tttgttagaa aatgaatata gtagactaaa tgcaactcct acaaatttag
       61 aactatcgtg gtgcgaagga acttcaggaa tcttacttta ttttgagtta ttatatgaca
      121 aaaggtattc aaacataatt tcaaggtttc aacaacttgc tttcaaattc aatcttatcc
      181 agtcaagttg ttattgtcat ggcttatcca gtttgttgca aactctaaac tatcaggata
      241 aattaaattt acgtgagaat gtgattgaga ttttattaag tagatccaaa agagataaaa
      301 atggtatttt ggtatttgaa tgtgaagaaa gttcagatac attatttgat tttggtatcg
      361 gaaatctagg gatttattgg tctatccttg gggaaagatt cccatttgaa cttaagaagg
      421 agttgtgatg aaagtatttc ttcaaaatag agattttagg caattaacta tcaaccagtg
      481 gatttcaacg cttggggata cgatttttta tctggccttc ctgaattatg tggcagatgc
      541 atcttttgcc cctttggcga ttttactcat cacgatttca gaaaccctgc cccaagttct
      601 acaaatcttt ctgggagttt tggcggattt tcaacatcat cgtgtcttga aatacacagt
      661 cattagtttt gcaaaatttt tgctttactc tatagtgtct ttatcacttt cagggcagtc
      721 cttttccttg ttattagtag catttatttg tctgattaac ctcttgtctg acacgttgag
      781 ttatttttca ggcgccatgc tcactccgat tttcattaga attattgggc aagaccatct
      841 ggcagaagct attggattta aacagtcaac tgttagttta gtgaaaacaa tcagtaatat
      901 tctaggagga gtcttattag gtattctatc catccagttt atttccttgc tgaacgctct
      961 taccttttta atcgcatttt taggtatcct cttcataaaa actgacctct tgaaagtaga
     1021 aaaaacgatt aactatcaag aaggactctc tgtaaaatcc ttttgccagc atttgctcca
     1081 atcatcgaaa ttgatatgga atatgaataa ggtgctcttg gttttgttta ttatctctac
     1141 tagtcaagca gtgataaatg ttacagttcc tgtctctact ctatttttga ggaatcaacc
     1201 ctttttgaat ttacaaacag gtcaatctct tgccttgcta tccacttttg aactgtcagc
     1261 cctgattgtc ggaagccttg taagtggcta tctgcaacat accatttcca taaaaacagc
     1321 tctctatgcc tcacttgtca cccagttgct tcttctagta ggatttgcca cagttcgttt
     1381 tgactggatt ctcatcttta gtaccttgga tgcctttttc gcaggtgttc tctctcctag
     1441 attgcaagaa ctcgttttta aacaaatacc tgaggagtca atgggagcag ttcaatcctc
     1501 tatcggtgcc attacggttg ttttacctag cttatttaca atagctttgg taaccattgc
     1561 tactagcttt ggaactctgg cagttagctt tgttttattg ctatttcttc tagttgcctt
     1621 tgttatgctt ctgaatattc gtgaaagtat ttagtggaga atttctataa tatatgtttg
     1681 agactggatt gccagccttt ttatgatggt caaaatcaac agactttttt ctcttttctg
     1741 aatgtgttat aatagactga atctaaaata gtacgaaaca attgctaaaa catttattta
     1801 tagaaattaa ttttactttc ccaatcgatt tgttctcatc ttatttcaat ctgctatata
     1861 atagtccatg ctgtggctgg attcttttca gcctacttat actcttcgaa actctcttca
     1921 aaccacgtca gcttcacctt gccgtaggta tggttactga cttcgtcagt tctatccaca
     1981 acctcaaaac agtgttttga gctgactacg tcagttctat ctgcttttca ttgagtacta
     2041 ttaagacaat atgaggagaa agatgaaaga aaaaggattt taggaggggg cgcaggcagc
     2101 catgccaacg gctcttggct atgtcagtat cggcctggcc tgtgggacta tcggtgcgcc
     2161 ctatgtgaca cctgttgaga tgggcttgat gagtctcttt gtttatgctg ggagtgccca
     2221 gtttgccatg ttggcactga ttgtggttca agctcctgtg gcagctattg ctatgacggt
     2281 ttttctaatc aacttgcgtc tctttttgtt gagtttacac gcatcgactt atttccgtca
     2341 taccagtctt tggtacaata tcggtatgtc tagtatcttg acagatgaga cctatggcgt
     2401 tttgatgggt gaattggccc atacagacaa ggtaaatcct atgtggatgc acggaaacaa
     2461 tcttaacagc tatgtggctt ggtttgtggg gacagtagtc ggaacggctc tgggtggcct
     2521 gctaccaaat ccagaaatct ttggcttgga ttttgcccta gttgggatgt ttattggtat
     2581 ttttgcttcg caatttcaga ttatgcaaag acggattcct gtccgcaatc tgctcattat
     2641 cctagcagtt gttgcggtgt ccttcttttt gctcttgaca gtggtgtctc agtcactagc
     2701 tgttctgttt gcgacgctac ttggttgtag catgggggtg gttttagatg gtcagtaagt
     2761 atcttttatt agcagttatt ttctctggct tggtgacttg gattctccgt atgattccct
     2821 tcatcttagt caagtataag ggcttgcctg caatcgttga gcgttttttg aagttcttgc
     2881 ccgtttccat tatctttgcc ttgattcttt caagcgtagt gacaggtaag gttgggagcc
     2941 ttcctcaaat taaatggcta gacttcttag ccgtctttcc aacagcttgg gtagcctttc
     3001 gctaccgcaa tctagtcgga acagttctct ttggagtggt cttgattgcc atcttgcgtt
     3061 tggtctttta aattacccat aaaaaaaact tatcacagag atagatatca tataatggcg
     3121 taaatgctct ttttctgtta agattataag gtattctatt ttggaggaaa tgacatgaaa
     3181 aaaatcgtta aatactcatc tcttgctgcc ctaggacttg ttgctgcagg tgtgcttgcg
     3241 gcttgctcag ggggtgctaa gaaagaagga gaagcagcta gcaagaaaga aatcatcgtt
     3301 gcaaccaatg gatcaccaag gccatttatc tatgaagaaa atggcgaatt gactggttac
     3361 gagattgaag tcgttcgcgc tatctttaaa gattctgaca aatatgatgt caagtttgaa
     3421 aagacagaat ggtcaggtgt ctttgctggt cttgacgctg accgttacaa tatggctgtc
     3481 aacaatctta gctacactaa agaacgtgcg gagaaatacc tctatgccgc accaattgcc
     3541 caaaatccta atgtccttgt cgtgaagaaa gatgactcta gtatcaagtc tctcgatgat
     3601 atcggtggaa aatcgacgga agtcgttcaa gccactacat cagctaagca gttagaagca
     3661 tacaatgctg aacacacgga caacccaact atccttaact atactaaggc agacttccaa
     3721 caaatcatgg tacgtttgag cgatggacaa tttgactaca agatttttga taaaatcggt
     3781 gttgaaacag tgatcaagaa ccaaggtttg gacaacttga aagttatcga acttccaagc
     3841 gaccaacaac cgtacgttta cccacttctt gctcaaggtc aagatgagtt gaaatcattt
     3901 gtagacaaac gcatcaaaga actttataaa gatggaactc ttgaaaaatt gtctaaacaa
     3961 ttcttcggag acacttatct accggcagaa gctgatatta aataatttct tgaaatcatc
     4021 cattctgagt aaggtgggtg gtttctcagt ttttagggat atagttttaa actatatatc
     4081 tgactatcta ataacaattt gtgaaatcaa acaaattgtg agatactagt acggtattat
     4141 ttttaaggag aaagaatcat gaaaatcaaa aaatggcttg gcctagcagc ccttgctaca
     4201 gtcgcaggtt tggctcttgc agcttgcgga aactcagaaa agaaagcaga caatgcaaca
     4261 actatcaaaa tcgcaactgt taaccgtagc ggttctgaag aaaaacgttg ggacaaaatc
     4321 caagaattgg ttaaaaaaga cggaattacc ttggaattta cagagttcac agactactca
     4381 caaccaaaca aagcaactgc tgatggcgaa gtagatttga acgctttcca acattataac
     4441 ttcttgaaca actggaacaa agaaaacgga aaagaccttg tagcgattgc agatacttac
     4501 atctctccaa tccgccttta ctcaggtttg aatggaagtg ccaacaagta cactaaagta
     4561 gaagacatcc cagcaaacgg agaaatcgct gtaccgaatg acgctacaaa cgaaagccgt
     4621 gcgctttatt tgcttcaatc agctggcttg attaaattgg atgtttctgg aactgctctt
     4681 gcaacagttg ccaacatcaa agaaaatcca aagaacttga aaatcactga attggacgct
     4741 agccaaacag ctcgttcatt gtcatcagtt gacgctgccg ttgtaaacaa taccttcgtt
     4801 acagaagcaa aattggacta caagaaagca cttttcaaag aacaagctga tgaaaactca
     4861 aaacaatggt acaacatcat tgttgcaaaa aaagattggg aaacatcacc taaggctgat
     4921 gctatcaaga aagtaatcgc agcttaccac acagatgacg tgaaaaaagt tatcgaagaa
     4981 tcatcagatg gtttggatca accagtttgg taataagaaa cagggaggtg ggagagaaaa
     5041 ttccacctct tgcttttgta tagagtatag attgtaaaga agactattcg ttcatagaaa
     5101 ggtagagaga atatggtttt tcctagcgaa caagaacaga ttgaaaaatt tgaaaaggat
     5161 catgtagccc agcattattt tgaggttttg cgtaccttga tttctaagaa atcagtcttt
     5221 gcccagcagg ttggactcaa ggaagtcgca aattatctgg gtgagatttt caagcgtgtt
     5281 ggagctgaag tggagattga tgagagctat acagcgccct ttgtcatggc acatttcaag
     5341 agttcgcgtc cagatgccaa gaccttgatt ttctataacc actatgacac tgtgccagcg
     5401 gatggggatc aggtctggac agaggatcct tttacgcttt cggtccgcaa tggcttcatg
     5461 tatgggcgtg gagttgatga cgacaagggt catatcacag ctcgcttgag tgctttgaga
     5521 aaatatatgc agcaccatga tgatttacct gtcaatatca gctttatcat ggagggagcg
     5581 gaggaatcgg cttcaacaga cctagataag tatttggaaa agcatgcaga caaactccgt
     5641 ggggcggatt tgttggtctg ggaacaaggg accaaaaatg ccttggaaca gctggaaatt
     5701 tctggtggca ataaggggat tgtgaccttt gatgccaagg taaaaagcgc tgatgtggat
     5761 atccactcga gttatggtgg tgttgtggaa tcagctcctt ggtatctcct ccaagcctta
     5821 cagtctcttc gtgctgcgga tggccgtatc ttggttgaag gcttgtacga agaagtacaa
     5881 gagcccaatg aacgagaaat ggccttgcta gaaacttatg gtcaacgaaa cccagaggaa
     5941 gttagtcgga tttatggatt ggagttgcct ctcttacagg aggagcggat ggcctttcta
     6001 aaacgtttct ttttcgagcc agcgcttaat atcgaaggaa tccagtctgg ttatcaaggt
     6061 cagggtgtta agactatttt acctgcagaa gccagtgcca agctagaggt tcgtctggtt
     6121 ccgggcctag aaccgcatga tgttctggaa aaaattcgga aacagctaga caaaaatggc
     6181 tttgataagg tagaattata ctataccttg ggagagatga gctatcgaag cgatatgagc
     6241 gcaccagcca ttctcaatgt gatcgagttg gccaagaaat tctatccaca gggcgtttca
     6301 gtcttgccga cgacagcggg gacaggacct atgcatacgg tctttgatgc cctagaggta
     6361 ccaatggttg cattcggtct aggaaatgcc aatagccgag accacggtgg agatgaaaat
     6421 gtgcgaatcg ctgattatta cacccatatc gaattagtag aggagctgat tagaagctat
     6481 gagtagagat attatcaagt tagatcagat cgatgtgact tttcaccaaa agaagagaac
     6541 catcacagcg gttaaggatg tgaccattca catccaagaa ggggatatct acggaatcgt
     6601 tggatattct ggagcaggaa aatcaaccct tgtacgggtg attaatctct tgcaaaaacc
     6661 atctgcaggg aaaattacca ttgacgacga tgtgattttt gacggcaagg tgaccttgac
     6721 ggcagagcag ttgcgtcgta aacgtcaaga tatcggaatg attttccagc attttaacct
     6781 gatgagccaa aagacagcag aggagaatgt agcctttgcc cttaaacact ctgaactcag
     6841 caaggaagaa aagaaggcta aagtagctaa gttgttggac ttggttggtt tggcagatcg
     6901 tgctgaaaac tacccttcac aactatctgg agggcaaaaa cagcgtgtgg caattgcgcg
     6961 tgccttggcc aatgatccaa aaatcttgat ttcagacgag tcaacttctg cccttgatcc
     7021 gaagacaacc aagcagattt tggccttgtt gcaagatttg aaccaaaaat taggcttgac
     7081 tgttgtcttg attacgcatg aaatgcagat tgtcaaagac attgccaacc gtgtggcggt
     7141 tatgcaggat gggcatttga ttgaagaggg tagtgtgctt gaaatcttct cagaccctaa
     7201 acaacctttg actcaagact ttatctcaac agctacaggt attgacgaag ccatggtcaa
     7261 aatcgagaag caagaaatcg tggaacactt gtctgaaaac agtctcttgg tgcaactcaa
     7321 gtacgctgga gcttcaacag acgagccact tttgaatgaa ttgtacaagc attaccaagt
     7381 aatggctaat attctctatg ggaatatcga aattctcgat ggtactcctg ttggagaatt
     7441 ggtggtggtc ttgtcaggtg aaaaagcagc gttggcaggt gcccaagaag ccattcgtca
     7501 agcaggtgta caactaaaag tattgaaggg aggacagtaa gatggaatca ttgattcaaa
     7561 cctatttacc aaatgtctat aaaatgggtt gggctggtca ggcaggctgg ggaacggcta
     7621 tctacttaac tctttatatg acagttcttt ccttcattat cggaggcttc ttggggctag
     7681 tggcaggtct ctttctcgtc ttgacagcgc caggtggtgt cttggagaat aaagtcgtat
     7741 tctggatttt agacaaaatt acctcaattt ttcgtgcggt tccctttatc atcctcttgg
     7801 caatcttgtc accactttct cacttgattg ttaaaacaag tatcgggcca aatgcagccc
     7861 ttgtcccact ttcttttgca gtctttgcct tctttgcccg tcaggtgcag gttgtcttgg
     7921 ctgaattgga tggcggtgtc attgaggcgg ctcaagcgag cggagcgact ttctgggaca
     7981 tcgtgggtgt ttacctatca gaaggtcttc cagatttgat ccgtgtgacg actgtgacct
     8041 tgatttccct tgttggggaa acagctatgg ccggtgcggt tggagctggt ggtatcggta
     8101 acgtagccat cgcttatgga tttaaccgct acaatcacga tgtgaccatc ttggcaacca
     8161 tcgttatcat tttgattatc tttgcaatcc aattcttagg agatttcttg actaagaaat
     8221 tgagccataa ataaaaaaga gccgtgtggc tctttttaac tgatcagatt ttctgggcaa
     8281 attttttact caaggcttgt ccaatcaagg cacccactag ggctccgatg acaatacttg
     8341 cgataaatag aaggacagtt ccagggtttg gagtgaccat gatacggtcg atatattctt
     8401 gggattttcc tcttgccaga agagtagcca tataggcttt gggcgcaatc cacataagca
     8461 agattggtcc tgttgtacta aaggcgaaaa taatgaaaga aaggaagttc tttgttttgt
     8521 ccttgtattt tcctaaatga gctacttcat ctgctaggag gccacagata attccaggaa
     8581 ggaaggaacc agcaccgtgt ttagttccca agaaaaagag ggcaatgaca aggccgatag
     8641 tggtaatggc tccaaagcgc ggaacttttg cgactaggat catatagacg ctaccgccga
     8701 caagggcagt aaaggcaggc gcataaaaca tgtttccagt ttggtcaaag agattgccca
     8761 aaaggacacc aatccccatg cagaggaagt aaagaactgc aaaaagcagt gtagttaaga
     8821 tagatttctt catgaattgt ctcctgataa ttttttcaca attctcattg taccacggtt
     8881 tggtgggatt gtaaatggat actagaagtt tttgaaaacg cttgaaatat gatataatgg
     8941 tttcatagtt atttttaggg gaatatcatg ggtagatttt tagactttgt ctttaatcgt
     9001 ttctttttag ggatgattgc gacagccttc ttttggctat taactttagc aggagggatt
     9061 atccttggtc tagcgccggc tagtgccacc ttgatgagct tatatgcaga acatggttat
     9121 agctttcggg aatacagttt gaaggaggct tggtctcttt acaagcaaaa ttttgtctca
     9181 agcaacctga ttttctatag ctttttaggt gtgggtctag ttttgaccta tggtttgtat
     9241 ctattggtgc aattgcctca tcagaccatt gttcatttga ttgcgaccct tttgaatgtc
     9301 ctagtagttg ccctgatctt tttggcttat acagtatctt taaaattaca agtttatttt
     9361 gccttgtcct atcgaaatag tctcaaatta tccttgattg gcatctttat gagtctagca
     9421 gctgtggcca aggttctcct tgggactgtg ctacttgtag caattggtta ctatatgcct
     9481 gccctgctat tttttgtagg aattgggatg tggcatttct ttatcagtga tatgttggaa
     9541 cctgtctatg aaatcatcca tgaaaaattg gcgacaaaat agaatgaagc agttttggct
     9601 acatacgctt ctaagaacct atagttcagt gatgatcatt atcattgcga gttttgcaat
     9661 cttactctct tacgctgact gggattcacg tgaaaaggaa gcccagagag tagcccagcg
     9721 tgtaactgct agaacagtga gtgaaattga atattaccat agagagtcaa cccagatagc
     9781 tcaggcttta gttgaaaatc aagctcgtat tgagggaatc tataaatact ttagccttag
     9841 catgccagac tatttttact ggcaattaga gcggaaagct tcgccttata tatcagtctc
     9901 tctgtatgaa aatgttgatg acctctatgt tcgaaatgat tttgtaactg gggtggccat
     9961 tgcttttcaa gattacaagg aagtctatgt ttctactaaa gacaaacgta gtggagaaaa
    10021 aatcagggct gaggatttca aaccagcagg aaatagtttt gccattccgg tgtcagatcc
    10081 agtgtcagat caagatttag gagtgattta catctccttg gatcctgctg ttttatacca
    10141 tgccattgat aatactagag gtcatactcc gatggcagta acagtgacct caccttttga
    10201 tacggagatt tttcatattg gtgagacagt tgatagggag agtgaaaatt ggctagttgg
    10261 cttaacttct catggatatc aggttcaggt ggcagttcct aaaaactttg ttttacaagg
    10321 aacagtgact agctctgctt tgattgtggg tttgagcctt ctctttattg tcattcttta
    10381 tctgactttg aggcagactt ttgctaatta ccaaaagcag gtagtggatt tagtagaatc
    10441 cattcaagtc attgctcaag gcgaagaggg gcgtcggatt gacatttccg agaaagatca
    10501 ggaattactc ctaatcgcgg agacgaccaa tgatatgttg gatcgattgg aaaagaatat
    10561 ccatgatatt taccagttag agcttagtca aaaagatgcc aatatgcgag ccttgcaggc
    10621 gcaaatcaat cctcatttta tgtataatac gctggagttc ttgcgcatgt atgcagttat
    10681 gcagagtcaa gatgagttgg cagatatcat ttatgaattc agtagtctct tgcgtaacaa
    10741 tatttccgac gaaagagaga ccctcctcaa acaggaatta gaattttgcc gtaaatacag
    10801 ctatctctgc atggttcgct atcccaagtc cattgcctat ggtttcaaga tagatccaga
    10861 gttagagaat atgaagattc ccaagtttac cttgcaaccg ctggtagaaa actatttcgc
    10921 gcatggtgtt gaccacaggc ggacagataa tgtgattagc atcaaggctc ttaaacagga
    10981 tggttttgtg gaaattttgg tggtcgataa tggtagagga atgtcggctg aaaagttggc
    11041 aaatatccga gaaaaattaa gtcagagata ttttgaacac caagccagct acagtgatca
    11101 aaggcagtct atcgggattg tcaatgtaca cgagcgtttt gtgctctatt ttggagaccg
    11161 ctatgccatt actatagagt ctgcagagca agccggtgtt cagtatcgta ttacaattca
    11221 agatgagtag aaagggagaa aatgtataaa gtattattag tagatgatga gtacatggtg
    11281 acagaaggtc tgaagcgttt gattcccttt gataagtggg atatggaggt tgtcgcaaca
    11341 gccagtcatg ccgatgaagc tctagaatat gttcaggaaa atcctgtcga tgtcatcatt
    11401 tccgatgtca atatgccaga caaaacaggg cttgatatga ttcgggagat gaaagagatc
    11461 ttaccagatg ctgcctatat cctgctctca ggttatcagg agtttgatta tgtaaaaaga
    11521 gcaatgaacc ttagtgtggt ggactatttg gtcaagcctg ttgataaggt agagctggga
    11581 aatctgctgg agaagattgc aggtcagctc ggcgagagag ggaagaaaag tcagactctt
    11641 agtcaagaat tagacgaggc tggatttgtt agttatttag gggataagga gaattggtgg
    11701 ataggtctat ccaaggaaaa acaaggttcc ttcaccattc cctactatgt cttgggccaa
    11761 gactggcaga ttttcatttc tggccaacct ctagatggtt tagtcgttac accttttgaa
    11821 gctccttatc aagaacactt tgaacgctgg aagctgaatg ctgagaaaac cctcttttac
    11881 ggttctgtaa atttgcagca gtctgagagt ctctttgcct attacgaacc gatttatagg
    11941 gttatcattc agggaaatct caatcaaatc gtagaagagt taaatctctt ggagaaggta
    12001 gttcttgaaa atacgccgcg tgttccgatt actaaacagc tttttattca gtttgtcatg
    12061 gatgttttcc atttatttga acatctcaaa gctgatgacc tgacagacat cgtcaaaacc
    12121 attcatgcta ttcaatcctt cgatgaattg gtttcttata tcaaggaaac tctgatcagc
    12181 tttttcggtc aataccgtat gaatgaaaat gtggtcagtg tgctggaagt cattggtcgt
    12241 gattaccaaa aagagctttc cctcaaggat atcagtaagg ctctctttat caatcctgtc
    12301 tatctagggc agttgattaa gcgtgaaacc gattcgacct ttgcagagtt actaaacaaa
    12361 caacgtatta aggctgccca acaacttttg ctttcaacta gtgacagcat cgaagatatt
    12421 tgttatgctg ttggttacag taaccttgga tatttctata aagttttccg aaaattgtgc
    12481 ggaaaatcgc caaaagccta ccgaaaacag gtagaaacta tactataaaa tttgtattcc
    12541 tttacaaaag gtgctataat attatcagga ggttctatca tgaaaaagaa accaatttat
    12601 ctatgggtct tgctaatctt gtctgccctt atttcagttc cgtctctgtt tggaattgtg
    12661 agtcccttgc ctagtaagga agcccttcgt gctgctcaga aacaagttgc aggggtcaat
    12721 gctcagcaat tagaagacca gcttaattat acctatagag tagcagaagc atctcattct
    12781 atttttaatg ttgctttgat tgtgctatct actattttag tggtcgtagc gattgtcttc
    12841 cttgttcgta aaaatttgca atatgcaaac tatacttacg ttggctatgt tttgttagct
    12901 attattggtt cgatttatgg ctatgttggt ttacaagacg ctgtgcagtt ggttcaagat
    12961 gagagcatgc gtttgacagt gagtattggt tcaaaagctg ttagcatttt ctatatcgtc
    13021 atcaatgttc tcttcctagc ccttgtcttc tataagatgt ggcgacaaca gaaagccttg
    13081 gcagaagaag aggaaacaga agagcttgcc taagtattga caaaaaagaa ctatcaagat
    13141 acaatcttgg tagttgtttt ttgattatag ataaaatcat ggaggtacat atgaagacaa
    13201 tttctttagt ttatattagt ttgagtggca acactgaaag ttttgtgacg cgcttgaaag
    13261 actatctctt gtcccagtac aaagggattg aggttcaaaa gattcatatc aaggatttag
    13321 tcaaggaagg caaaaatttc tatgaaatgg accatcccta tgtcgctttt ttgccgacct
    13381 atctcgaagg tgggaatggc gtggataacg gagatgttga gattttgacg acaccggtgg
    13441 gagattttat tgcctatggt aacaatgcta gtaagtgttt tggtgtggtt gggtcaggaa
    13501 atcgtaactt taataaccaa tactgcctaa cagccaagca atacagtcaa cgctttggct
    13561 ttcctgtatt ggctgacttt gaaatgcgag gcatgctgga agatatcaaa catgtcgcag
    13621 ctattatcgc agatttgtat gagttggaaa aggagaatta atactcaatg aaaatcaaag
    13681 agcaaactag gaagctagtc gcaggttgct caaagcacag ctttgaggtt gcagatagag
    13741 ctgacgtggt ttgaagagat tctcgaatag tataaagttc ttataagagg tggttgaagt
    13801 tgttcaactg ttttttgagt ataaacagtc tttaagaacg taaaaaagca taagttcagg
    13861 tcttcaaaac cttgttctta tgctttttat catagaaata tttgctgaat tttctcttga
    13921 aatgaaacct tatcttcatc tcgcgcttgt cccttaccct gcttttccga ttgcgagtgc
    13981 gtagataaag aagatggcga agccaaagag gaaaatcaat cccgcaatgg caaggtgttt
    14041 gagccaagaa ggaagatttt tgttttcacg cgttaccaag gcgtaattca aaagagcaaa
    14101 gaaaggtgtt gtcaggaaag agccaatcat ggcaaagcgg agcatggttg aaacctgacc
    14161 agcgaagaac ttgataatga cgataccgat gatagcagtg atggtcatcc agatgttcaa
    14221 agatttacga ttgtcctctt tttgactgat tagcagtcgg agagattcct gattaacgcg
    14281 agaatagcca tcgataacag ttataactgt tccaaagata cagaggaagg caataaaggt
    14341 aatcaagtaa cgggaccatt cgccaagaac agaggcatac atgcccacga attgagagat
    14401 gtatttggct gaagcagctt caaccgcctg ccctgtagga tactgaatca gtgctcccag
    14461 tgccacaaag aagacggcta ggatagctgt tccaatataa ccagtgttaa agtcaaacac
    14521 agcgtcttct gtgttaaagt tgacggtctt tctcttttca gctgaccaaa gtgaattgat
    14581 ggctgaaatt tcaataggag ccggcatcca tcctaggagg gagacgatga agggcagagc
    14641 tgccatttgc caaggtgtct tctcgacaaa atcagaactg tattctggat gcttgaccgc
    14701 cgcaatgata actgcaagaa cagtcgcaat ggttaaggca gacataatcc atttgaccat
    14761 gccgtctaaa agtttgtagc ctccaaagag tagcatagcc caaatgattg caacgagaat
    14821 gagggaccac tgagtaatgc taagtccaat cattgggaag gcactggcga tgatagctga
    14881 gcacagaatg gcaacaccag ccgtgttgac catagccgaa aagacattga ggataaagaa
    14941 aatccagaga tagagttttc ctttttcggc ataaccttca accaaagtct ttccagtatc
    15001 agctgtgtat tcagcaccaa aacggaaaaa tggatattta aagacattgg ctaagatgac
    15061 caagagaagt agagaccaac cgtaagaacc gccagcttga gttgaggata caatgtggga
    15121 acctccaaca gcggcagttg ccattaggat tccaggtccc attgctttta gcttgcttgc
    15181 ccaggttgat tgatttaagg aaatagcttg cgacatgata aatactcctt tttgaatttt
    15241 cagaataatc tgtatatgta atctatattc tacaaaaaat tttggaaaaa tgcaagagta
    15301 ttttgaaaaa agatagaaaa tttacaaaga aaatctgaaa taactgttat gatatagcag
    15361 attgaaacta gaatagtaca cttttgcttc taaaacattg ttagaaatcg atttgactgt
    15421 cctgattgat ttaccctgtt cttatttcat ttcactatag taaggtgcag caggataaag
    15481 caaaaccgag aagtttcttt ctcggttttg cttattatga ggttcctatt ttctatgctc
    15541 caagagttga ttgatgtgat ctactttttt agcctctctt ttatagagaa tagcccagat
    15601 gatgagatag acaatcgcaa actcgataat gagctggagg tagaaaatcc agtggaaggg
    15661 gaaccaacca gcaagagttg ctagtgggac aaagccagcc agcataagga agaaatgagt
    15721 cagagtggca cgaagcatgc tccagtcacg gctgaataag cggttgccaa agttgaagag
    15781 cataccgatg gctgcccaga taagtgtgca gtagagcaag accagggcac cgtgaacctg
    15841 atgctgatcc atcacttggc cgatgagaga gtagggattt agtggtgcgt aggtatttgg
    15901 tgcataaatg agtgaaaaga ggatggagag gatgaggccg ataagaacac cggcagctgc
    15961 atcgtgaaat acttgttttt tcatagttct aatttctcct tgatggtttt tagataacgg
    16021 cgtgaagagt aggtgaagct ttcgtttttc aagaaaattt ctaccagacc gtttggcgtg
    16081 agcttgaggt gagagatgga atcgatattg atgatttctg attgggaaat ttggataaaa
    16141 ttggttggca agagtttaag aacctgatag agtcgcaaat caatgctgta ggtctgactc
    16201 gcggtttctg ctagaacctt ccgattctcg atatagaagc gctgaatctt gccaatctca
    16261 actagataga cctgatcatc gatttttcct ttgatttttt ctctttggtc cagattttct
    16321 gcgaactcga tgactttctg gactttttcg gtttcttgag gtgcttggac aatcagcttt
    16381 tcctcctcgt aagtctcact aatctgtagt tctactttca taaatttctc tccttgtttt
    16441 tcatacaaaa ttaatctcac ttcttgtaca cctttattaa tactcttcaa aaatctcttc
    16501 aaaccacgtc agcgtcgtct tgccgtagga tagttgttga ctttgtcagt tttatctaca
    16561 acctcaaaac agtgttttga gctgtctgcg tctagctttc tagtttgctc tttgattttt
    16621 attgagtata ccactatttt actccctctg gcaagggact ttgtctatgt ggagggattg
    16681 ggctcctatg tggtggagtt tttctgttct ttctgaaata tggtataata gcactaatta
    16741 atttctagga aaatagatac agaaaggggc tgaaagatgt ctcatattat tgaattgcca
    16801 gagatgctgg caaaccaaat cgcagctggg gaggtcattg aacgtcctgc cagtgtggtt
    16861 aaagagttgg tagaaaatgc cattgacgcg ggctctagtc agattatcat tgagattgag
    16921 gaagctggtc tcaagaaggt tcaaatcacg gataacggtc atggaattgc ccacgatgag
    16981 gtggagttgg ccctgcgtcg ccatgcgacc agtaagataa aaaatcaagc agatctcttt
    17041 cggattcgga cgcttggttt tcgtggtgaa gccttgcctt ctattgcgtc tgttagtgtc
    17101 ttgactctgt taacggcggt ggatggtgct agtcatggaa ccaagttagt cgcgcgtggg
    17161 ggtgaagttg aggaagtcat cccagcgact agtcctgtgg gaaccaaggt ttgtgtggag
    17221 gatctctttt tcaacacgcc tgcccgtctc aagtatatga agagccagca agcggagttg
    17281 tctcatatca ttgatattgt caaccgtctg ggcttggccc atcctgagat ttcttttagc
    17341 ttgattagtg atggcaagga aatgacgcgg acagcaggga ctggtcaatt gcgccaagca
    17401 atcgcaggga tttacggttt ggtcagtgcc aagaagatga ttgaaattga gaactctgac
    17461 ctagatttcg aaatttcagg ttttgtgtct ttacctgagt tgactcgggc taaccgcaat
    17521 tatatcagcc tcttcatcaa tggccgttat atcaagaact tcctgctcaa tcgtgctatt
    17581 ttggatggtt tcggaagcaa gcttatggtt ggacgttttc cactggctgt cattcacatc
    17641 catatcgacc cttatctagc ggatgtcaat gtgcatccaa ctaagcaaga ggtgcggatt
    17701 tccaaggaaa aagaactgat gaccctggtt tcagaagcta ttgcaaatag tctcaaggaa
    17761 caaaccttga ttccagatgc cttggaaaat cttgccaaat cgaccgtgcg caatcgtgag
    17821 aaggtggagc aaactattct cccactcaaa gaaaatacgc tctactatga gaaaactgag
    17881 ccgtcaagac ctagtcaaac tgaagtagct gattatcagg tagaattgac tgatgaaggg
    17941 caggatttaa ccctgtttgc caaggaaacc ttggaccgat tgaccaagcc agcaaaactg
    18001 cattttgcag agagaaagcc tgctaactac gaccagctag accatccaga gttagatctt
    18061 gctagcatcg ataaggctta tgacaaactg gagcgagaag aagcatccag cttcccagag
    18121 ttggagtttt tcggacaaat gcacgggact tatctctttg cccaagggcg agatggactt
    18181 tacatcatag atcagcacgc tgctcaggaa cgggtcaagt acgaggagta ccgtgaaagc
    18241 attggcaatg ttgaccagag ccagcagcaa ctcctagtgc cctatatctt tgaatttcct
    18301 gcggatgatg ccctgcgtct caaggaaaga atgcctctct tagaggaagt gggcgtcttt
    18361 ctagcagagt acggagaaaa tcaatttatt ctacgtgaac atcctatttg gatggcagaa
    18421 gaagagattg aatcaggcat ctatgagatg tgcgacatgc tccttttgac caaggaagtt
    18481 tctatcaaga aataccgagc agagctggct atcatgatgt cttgcaagcg atctatcaag
    18541 gccaatcatc gtattgatga tcattcagct agacaactcc tctatcagct ttctcaatgt
    18601 gacaatccct ataactgtcc tcacggacgt cctgttttgg tgcattttac caagtcggat
    18661 atggaaaaga tgttccgacg tattcaggaa aatcacacca gtctccgtga gttggggaaa
    18721 tattaaaagt ataaaaaagt ctgggaaaaa ttttcaaaat cagaaaaacg cataaaatca
    18781 ggtgttcaaa aaccttgatt ttatgcgttt tatcatagaa atatttactt catgttttcc
    18841 taattctttt cgaaactctt tttaaaccac gtcagtttta tcagtaatct caaaacagtg
    18901 ttttgagcta attttgccag ttttgtctgt aacatcgaag ttgtgtttga ccactctgcg
    18961 actggtttcc tagtttgctc tatgattttc acagagtatt aaattgcgat tttgccaagt
    19021 ttctttattc gtctaaaagt agagtctgtt ctatgcgtct aatgtacgaa ttaggttgac
    19081 catttcaata gctccttgtg cacactcaga acccttattt cctgctttag tgccagctcg
    19141 ttctatggct tgttcaattg tatctgtcgt tagcacacca aacataacag gaatttcgct
    19201 atttaaactg atttgggcga ttcccttaga tacctcgcta catacataat cataatgact
    19261 tgtattccct ctaatgacag ctcccaagca gataattgca tcatattttt tactttttgc
    19321 catttttgat gcaatcagtg gtatttcaaa agctcctgga acccaggcta cctctatatc
    19381 tttctcgttt acattctctc ttttgagatt atctagtgct ccagataata attttgaagt
    19441 tataaattca ttaaatctcg ctacaacaat acctatttta atattgtttg ctactaaatt
    19501 accttcataa gtgttcattt atttttcctc catatttaaa atgtgaccca ttcgattttt
    19561 ctttgtttct aaataaaaac tatcgtaagg attggcttct atttcgattg atattctact
    19621 ggaaatggta attccatatt tttctaactg ttcaaccttg tcaggattat ttgtcagtaa
    19681 atgaagtgac tgaagtccca gatctttaag catttgtgct ccaatatgat attctcttaa
    19741 atcaccttca aagcctaatg caagattggc atcaagcgta tccatgcctt gatcttgtaa
    19801 atgataggct tttaatttat tgataagtcc aattcctcgt ccctcctgtc gcaagtaaag
    19861 taagacaccc gaaccattct caacaattat tttcatagct ttatcgaatt gctgtccaca
    19921 atcgcaacgt aaagagccta aaacatctcc tgttaaacat tcggagtgga cccgacataa
    19981 tacattggct tcatcctcta tgtttcccat aataagagca agatgatgtt ccccatttag
    20041 tttatctata tagctaattg ctttgaaatt accgtatcta gtaggcatat tgacagttga
    20101 aactcgttct accagctgat catatgcttt tctatattct tgtaattctt tgatggtaat
    20161 tagtggaatg ttgtgtttct tcgagaactg aattaaatca tctattctca tcattttgcc
    20221 atcatgattc attatttcac aacataggcc acactctttt agtccagcta attttaataa
    20281 atcaacagtt gcttctgtgt gtccatttct ttctagaaca ccaccttttt ttgcaattaa
    20341 aggaaacatg tgtcctggcc tgcgaaaatc agagggtgtt atatcttcag ctacacacat
    20401 acgtgcggtc agtcctctct cctcggcaga aatacctgtg gtcgtttctt tataatcaat
    20461 tgaaactgta aaagcagtct tatgattatc tgtattgttt tcaaccatag gtgaaagcat
    20521 taattgatta gctaaacttt cgctcatagg catacaaatt aatcctttgg cataagtagc
    20581 cataaaatta acattttctg ttgtagctgc ttgtgcagaa caaattaagt ctccttcatt
    20641 ttctctatcc ttgtcgtcta taacaagaac aagtcgtccc ttctgcaatg cttctaatgc
    20701 ttcttgtatt tttcgatatt ccattgactg attatccttt ctgctaaaat ccattttgat
    20761 ataatagttc cttcgatatt tctgattttg gagagttatc catcagtttt tgcacatatt
    20821 tacctaagat atcattttca agatttactg tactcccgac ttgtttactc ttaagaatgg
    20881 tttgtttcaa ggtatgaggg ataacagata ctgaaaagtt tactttggag actttagcga
    20941 cagtcagact aatgccgtca attgtaatag atcctttttc aactattaaa tctaaaattt
    21001 ctttttgtgt gttgatttga taccatacag cattatcatc tttttttatt gacgagattt
    21061 ttcctgtacc atcaatgtgt cctgtaacga cgtgaccccc aagtcgaccg ttgacagata
    21121 aggctctttc tagattcacc tcacttccat gttttaatag agtaagagct gttcgactcc
    21181 atgtttcatt cattacatca actgtaaagg attgatgatt gaaatgagta actgtaagac
    21241 agataccatt tactgctata ctatcgccta aatggatatc cgttaatatt tttgaggctt
    21301 taattgatag tttacaatta cgagagtctt tctgtattct ttcaactttt ccgatttctt
    21361 caattattcc tgtgaacatg gataaatcac ttcactttct atgagatagt catttcctat
    21421 ttgagaaaaa gcataaggtt tcaatctaat agcgtcattt ggcaaagaaa tgccttcacc
    21481 tccgacagga aacttggcac tgcctccaaa aatttttggt gcaatatata ttttcagctc
    21541 atcaacaatt tgttgttcca aagcactcca attcattaga ctgccccctt ctagaactag
    21601 gctatcaatc tgcatgtttc ctagatgttg cattaaactc gataagtcta tatgattgcc
    21661 ttttttcttt atggaaagta tttcacagcc atgattttga tatagcttca ttttattttt
    21721 gtcttcagag gaagtggcaa tgtaagtttt aatatcattt gctgttttta cgattttaga
    21781 ggtaagagga gttcgtaaat gtgtatcgca tatgatacgg ataggatttt tcccttcctc
    21841 caatctacat gtcagcaaag gatcgtcttg aataacagta ttgactccca ccataattgc
    21901 actaacatgg tgtcgtaact gatgcacatg ctttcttgcc tcttcttcag taatccattt
    21961 ggattgattt gttttagtgg ctatttttcc atccattgtc attgcatatt tcataaaaac
    22021 atagggtaca tgctgggtaa tatactttct aaaacttttt attaagttaa gacactcatt
    22081 ttctaaaatt ccaacagtaa cttgaagatt attttcctca agtatcttta ctccttttcc
    22141 agatacaata ggattacagt ctaggcttcc aatgactact cttgtaatac cactatcgat
    22201 tatagcatct atacaaggag gtgttttccc gaagtgacaa cagggttcaa gtgttacata
    22261 aagcgtcgct ccgacagggg attctctaca gtttttaaga gcatttctct cagcatgtga
    22321 gccaccaaaa aactcatgat aaccttgtcc gatgatgtga ttatctttta caataactgc
    22381 gccgaccata ggattgggat tgacgtaacc agcccctttt tgtgccagtt ttattgctaa
    22441 tttcatatat tttgaatcgc tcatctcact acctccaaaa aaatatacct tgaataggag
    22501 actactcaag gcatacaaaa gaaaacttat gcgattaaca aaaatgctct gaaatgacaa
    22561 gtaatcattt cagagcacgc aaaaagcaca aatatacttt tatcttcttt catccagact
    22621 atactgtcgg ctttggaatt tcaccaaatc atgcctttcg gctcgtgggc tataccaccg
    22681 gtagggaatt gcaccctgcc ctgaagatag ttattcaatt acagatgatt atagtactta
    22741 attttgaata tgtcaacaga taaataccga ttgtttttga tatactgtat ttgtgataat
    22801 cgattctcgc tcctcggata aagaaaatat gatatactag ataaacgaaa taagagagaa
    22861 ggaacactat gtacgcatat ttaaaaggaa tcattaccaa aattactgcc aaatacattg
    22921 ttcttgaaac caatggtatt ggttatatcc tgcatgtggc caatccttat gcctattcag
    22981 gtcaggttaa tcaggaggct cagatttatg tgcatcaggt tgtgcgtgag gacgcccatt
    23041 tgctttatgg atttcgctca gaggatgaga aaaagctctt tcttagtctg atttcggtct
    23101 ctgggattgg tcctgtatca gctcttgcta ttatcgctgc tgatgacaat gctggcttgg
    23161 ttcaagccat tgaaaccaag aacatcacct acttgaccaa gttccctaaa attggcaaga
    23221 aaacagccca gcagatggtg ctggacttgg aaggcaaggt agtagttgca ggagatgacc
    23281 ttcctgccaa gatcgcagtg caagcaagtg ctgaaaacca agaattggaa gaagctatgg
    23341 aagccatgtt ggctctgggc tacaaggcaa cagagctcaa gaaaatcaag aaattctttg
    23401 aaggaacgac agatacagct gagaactata tcaagtcggc ccttaaaatg ttggtcaaat
    23461 aggagcagag aatgacaaaa cgttgttcgt gggtcaagat gaccaaccca ctctacatcg
    23521 cctatcatga tgaggagtgg ggccagcccc tccatgatga ccaagcgttg tttgagttgt
    23581 tgtgtatgga aacctatcag gcaggcctgt cttgggaaac ggtactcaac aaacgccaag
    23641 ctttccgaga agcctttcat agctatcaaa ttcactcagt cgcagagatg actgacactg
    23701 aattggaagc catgctggag aatccagcta tcattcgaaa tagagccaag atttttgcta
    23761 cacgcgctaa cgcccaagcc tttctacagt tacaggcaga gtacggctct tttgatgcct
    23821 atctttggtc ttttgttgag gggaaaactg tcgttaacga tgttcctgat tatcgccaag
    23881 ccccagctaa aacaccctta tctgagaaat tagccaaaga tctcaaaaaa cgagacttca
    23941 agttcacagg cccagtcgcc gtattgtctt ttctacaggc tgcagggcta gttgatgacc
    24001 acgagaatga ttgtgagtgg aaaggtctta aatgatgtct aacaaaaata agggaattct
    24061 gatttttgcg attctctata cagtcctctt tgtgtttgat ggcgttaaat tgctggcttc
    24121 tttaatgcca tctgccattg caaattatct tgtttatgta gttttagctt tatatggctc
    24181 cttcttgttc aaggatagat tgatccaaca atggaaggag attagaaaga ctaaaagaaa
    24241 attcttcttt ggagtcttaa caggatggct ctttctcatt ctgatgactg ttgtctttga
    24301 atttgtatca gagatgttga agcagtttgt gggactagat ggacaaggtc taaatcagtc
    24361 taatattcaa agtacctttc aagaacaacc actactgata gctgtttttg cttgtgtcat
    24421 tggacctctg gtagaagaat tatttttccg tcaggtctta ttgcattact tgcaggaacg
    24481 gttgtcaggt ttactaagca ttattctggt aggacttgtt tttgctctga ctcatatgca
    24541 cagtttggct ctatcagagt ggattggtgc agttggttac ttaggtggag gccttgcctt
    24601 ttctattatt tatgtgaaag aaaaagagaa tatctactat cccctacttg ttcacatgtt
    24661 aagcaacagc ctctccttaa tcattttagc tatcagtata gtaaaatgaa atgagaacag
    24721 gacaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatata
    24781 ctgtaatatg tgatgaaaat gccagtaatg ataccgagaa aaaagctgag aaacttttcc
    24841 cagctttatt tgttatagtc aaagagaatg acttgttcct gtgcatctac atgagcatgg
    24901 accccaaagg gtacaattgc tcttggagtt gcgtggccga cattcagatt atagacaatc
    24961 gggatattgc tgtcaatgat atccaatagt gcctctttat agtcgtcatg gaaagtttca
    25021 tccataggtt ttccgaccaa gagtccattg atgaccgcga atatgccagt gtcctttaaa
    25081 gttagcaaca tctttttgaa gtcttctggc ttaggctttt cttcgcttgt ttcgagcaag
    25141 aggattttcc cttcccagtc tgacaagtca gggaaaagtt tgtatttttg gcagagttcc
    25201 gtgctatctg cgtatcgaga gttgtcaaag atatcgtaga gggattcgag gcaaccaccg
    25261 aggattttcc cctcgaactg agcacttcct tgcaacaagt caaaacctgt atttgtatga
    25321 ctgacacgag gtgttcccag ggccgtggga ctaaaatcag ttcgttcctc ataccaaacg
    25381 tcactagggc ggatttctga aattcttccc gtctcaatca attctttaaa gtagtgaagg
    25441 ctataggcta gcatttcttt gtctaattca caaatgtctg ctaaaaagga ttgaccataa
    25501 aaagtcttga ttcctaattt atgcaacatg aggtggttca tggttgtatc cgagaagcca
    25561 agaaaaattt tttgtttgat aaccttttgg agttggtcat tttcaaaaag ataaggtagc
    25621 aagcgatagg tatcgtctcc accgatggca cataggatca tgtcgatgct atcatcagaa
    25681 aaggcatgaa tcaaatcctc tgcacgagct tcaggatggt ccttgataaa gtctaatcct
    25741 tttaacgaat ggggcaaaaa gatgggattg agtcccagat ccttgagacg ttggataccc
    25801 aagtccactt cgtgtttgac aaaatcctct ccgataatgc cactagataa actaacaata
    25861 ccaatagtag aaaccatatc tcatcctcct agaaatagat tgagcctatt ttatcacaaa
    25921 atataagaga aagctatgtg ggatttcaga agaatacttt taatactctt cgaaaatctc
    25981 ttcaaaccac gtcagtttta tctgcaactt caaagctgtg ctttgagcaa cctgcagcta
    26041 gcttcctagt ttgctctttg attttcattg agtacaactc aaaaaagtaa gtgaaaaagc
    26101 aaccgcacct gcagttgctt ttatcgtttt cttattcttg atagcgtgtt ggtcctgcac
    26161 ttgcactacg gatattcaag cgtttcttga gatagaagcg aagggctagg agggctgctc
    26221 caataatagc tagtggcaat ggatccagta ctgggttaag gctagctggt aggaagcttg
    26281 ttgcaaagaa gacaagcaac caaaggaaca tagaagctag gataactagt acagatttcc
    26341 agaaaggtgg acgttgactg cgatccatat ctggtccata gtattggtaa acaaagtagt
    26401 acatcaagta gaaggcaaat ccaccaacca gtccaactaa tagaagagta atcaatccat
    26461 agccgaaagc ttgatctgcc gcaaagaagg ttgtgagggc gctgacaagg gcaaagaggc
    26521 tagtgatgaa aagagctgag tccataatca tcagttttgg atcatcattt tcttttggat
    26581 gctctttttc gtactgctct ttgacagtga agctatgagc ccaatgagtt ggtgcgccgt
    26641 atagggaacg ggcagttgta cctttagatt gctcctcaag gatttgggga atgacttcct
    26701 caaaaatagt ctggatttca gcgtctgttt tcccatcttt gatgaattgt tgggtagcaa
    26761 tgtggacaaa ctcttggttt ttcttagtta atttttgtag atcaatttga gacataggaa
    26821 ctcctcttag aaccattttt tatggatgag atagagagtg agcgagacac tcatagcaaa
    26881 ggcgataaag acgattaacc agaaggcatt tggctctccg tttaggggaa tttcattatc
    26941 cttaaagttc atcccgtagg cagaaaagac catggttggg atggacatga cgatggtcac
    27001 aagggccaag gttttcatga tgttgttctg gttgttagaa atgatagagg caaaggtctc
    27061 tgtcatagaa tgcaagacgt ttccataaat atctgccatc tcgatggcct gttgggtttc
    27121 aatcagggtg tcttcaagca ggtcttcgtc ctcaaggtat ttcttgatat tgctggttga
    27181 actggtcaat ttcttaatca cgcgctcatt tgttttgagg gaggccttga aatagacgat
    27241 agttttttcc aattccatga gctcaatcaa ttcttcatta cgagttgatt gatgcagttg
    27301 actttcgatt tgttcactct tgcggtcgat tgaacgaagg gctgttaggt aaagctctgc
    27361 attgcgataa agaatttgaa agataaaacg tgaacgcatg aaggtataga aattacgcaa
    27421 tcgacggttg ataaagacat caaggacagg tagtggttcc aaacacgtag tgataatggt
    27481 ttcctcagtg atgataatac caagcgggat ggttacgtag taggtgcggt tatttctttc
    27541 ctccgtgacc ggcacgtcta cgataatcag ggtatactcg tcttcaatgg taatacgaga
    27601 catttcttcc gcatcgagcg gtgctcgaag gtcggcaata tcaatatcga aggtgttggc
    27661 gatttcgagt gattcatttt gagtcggatt gacgagattg atccaagtac ccggttcaag
    27721 cgtatcgatc tctttaaatt cagttgttgt agagagaaaa acttgtttca tatcccttat
    27781 cctttctcat ttttcagatt ttttcacact gtactattat actacaaaat cggccttttg
    27841 ggtaatagaa tctcactttt tttggtataa tggtaagcaa taatggacta gaaagaacaa
    27901 agatgcaaga taaaattgtc attcatgggg cgcgtgccca taatttaaaa aatattgatg
    27961 tggagattcc gcgagacaag ttggttgtcg tgactggctt gtcaggttca gggaagtcca
    28021 gtctggcttt tgataccctc tatgcggagg gacaacgtcg ctatgtagag agtttgtccg
    28081 cctacgctcg tcagttcttg ggaaatatgg aaaaaccaga tgtagatgcc attgatggtc
    28141 tcagcccagc tatttccatc gaccagaaaa cgactagtaa aaatcctcgc tcgacggtgg
    28201 gaacgacgac tgaaatcaat gactatctgc gtctcctcta cgcacgtgtg gggacgcctt
    28261 actgtatcaa cggacatgga gctatcaatg cttcttcggt ggagcaaatc gttgataagg
    28321 ttttggagtt acctgaacgc cagcgcttgc agatcttggc tcctgtcatc cgcaagaaaa
    28381 aaggccaaca taagagtgtt atcgagaagg ttcagaaaga cgggtatgtt cgtgttcgtg
    28441 tggatgggga agtctatgat gtgaccgaag tgccagagtt gtctaagagc aagcaacaca
    28501 atatcgatgt cgtggttgac cgtattgtta tcaaggaggg cattcgtagt cgtctctttg
    28561 attccattga ggctgccctt cgtattgcag aaggttatgt cattatcgac accatggacg
    28621 attcggagtt gctcttctct gagcattatg cctgtccagt ttgtggtttt actgtcccag
    28681 agttagaacc tcgtctcttc tctttcaatg ctccttttgg ctcttgtagt gagtgtgacg
    28741 gcttggggat caagctggag gtggatactg atttggtagt gccagatgcc agcaaaacct
    28801 tacgtgaggg agcgctagca ccttggaatc ctatctcatc caactactat ccaaacatgt
    28861 tagagcaggc catgaaagtc tttggagtgg ctatggataa gccttttgag gacctgtcag
    28921 aagaagataa gaacttgatt ctctatgggt cagatggtaa ggaattccat ttccactatg
    28981 agaatgaatt tggtggcgtg cgcgatatcg acattccgtt tgagggagtt atcaataata
    29041 tcaaacgtcg ttaccatgaa accaatagcg attacactcg cactcagatg cgtctctaca
    29101 tgaatgagct gacctgcgga acctgtcaag gctatcgtct caatgaccag gtcttgtctg
    29161 tccgtgtggg cggccagcaa gggccacata ttggagaaat ctcagacctg tctatcgctg
    29221 accacttgga cttggtgagc cagttaactt tgtctgaaaa tgaagccatc attgctcgtc
    29281 ccattctcaa ggaaatcaag gatcgtttga ccttccttaa taatgtgggt cttaactatc
    29341 taaccctgtc acgttcagca ggaacccttt caggtgggga aagtcagcgc attcgtttgg
    29401 caacccagat tggttccaac ctatcaggcg tcctctatat cctagacgag ccgtcaatcg
    29461 gtcttcacca gagggacaat gaccgcctga ttgccagtct gaaaaagatg cgtgacttgg
    29521 gcaatactct tatcgtggtg gaacacgacg aagataccat gcgtgaagct gattatctga
    29581 ttgacgttgg tcctggtgcc ggtgtttttg gtggtgagat tgttgcagca ggtacaccta
    29641 agcaagtggc tcgcaacagc aagtctatca caggtcagta cttgtcaggc aaacgtgtca
    29701 tcccagtacc agaagagcgc cgtgtcggaa atggtcgttt tattgaagtg acaggagcgc
    29761 gtgagaacaa cttgcaaaat gtcacggctc gctttccact aggaaaattt atcgcagtga
    29821 caggtgtgtc gggttcaggg aaatcgactc taatcaacag cattctcaaa aaagccattg
    29881 cccagaagct caaccgtaat tcagacaaac ctggtaagtt taagactatt acagggattg
    29941 agcatgtcga ccgtttgatt gatattgacc agagccctat cggacggacg ccgaggtcta
    30001 acccagctac ctatacagga gtttttgacg atatacgtga cctttttgct cagacaaatg
    30061 aagccaagat tcgaggctac aagaaggggc gcttcagttt caacgtcaag ggaggtcgct
    30121 gtgaagcttg ctcaggtgac gggattatca agattgagat gcacttcttg ccagatgttt
    30181 atgtggcttg tgaagtttgc cacggaaccc gctataacag tgaaacccta gaagttcact
    30241 acaaggaaaa gaatatttcg caggtcttgg atatgacggt caacgatgcg gtagaatttt
    30301 tccaacacat tccgaaaatt caacgcaaac tccagaccat caaggatgta gggctaggct
    30361 atgtgacctt gggacagcca gctaccaccc tttctggggg agaagcccaa cgtatgaagt
    30421 tagctagcga actccacaaa cgctcgacag gaaaatcttt ctacattctg gatgagccga
    30481 cgacagggct tcatacagag gacattgctc gcctgctcaa ggttttagct cgctttgtag
    30541 acgatggcaa tacagtcctc gtcatcgagc acaatctgga tgttatcaag acggcagacc
    30601 atatcattga cttgggacct gagggcggtg tcggtggtgg aaccatcatc gtaacaggaa
    30661 ctccagaaga agtagctgcc aacgaagcca gctatacagg acactatttg aaaggaaagt
    30721 tacatcatga ataaacgcgt acaagcattt ctagctaaaa tgcaagaaaa agaactagat
    30781 ggtatcatca tcaacaatct taaaaacgtc tattatttga ctggtttttg gggctcaaac
    30841 ggaacagtct ttatcagtcg tgaccgtcag gtcttagtga cagactctcg ctatatcatc
    30901 gcagctaagc aagaaaccag tggttttgag attgtggctg atcgtgatga attggctgtc
    30961 attgcaggaa ttgttaagga catgggcttg actcgtatcg gttttgaaga tgagatttca
    31021 gtgtcttatt accaccgtat gcaggcagct tttgcaggtt tgaacttgct tccacaaact
    31081 cagtttgtgg aaggtcttcg tatgattaag gatgaggcag agattgcagc gattcgcaag
    31141 gcttgttcta tctcagacca agctttccgc gatgcgcttg actttatcaa accaggaaaa
    31201 actgaaattg agattgccaa cttccttgac ttccgcatgc gtgagttggg agcatctggc
    31261 ttatcttttg atacgatcct agctagcggt atcaattctt ctaaacccca tgcccatcca
    31321 atgcacaaac cagtggagtt gggagaagcc attaccatgg acttcggctg tctctatgac
    31381 cactatgtca gtgatatgac ccggactatc tatctagggc atgttagcga tgagcaggca
    31441 gagatttaca atacggttct aaaagctaac caagccttga ttgaccaagc taaggcaggc
    31501 ttaggtttcc gtgactttga caaaatccct cgtgatatta tcattgaggc aggttatggc
    31561 gactacttta ctcacggcat tggccacggt attggtctgg atatccatga ggaaccctac
    31621 tttagccaga cttctacaga aactattaag acaggtatgg ccttgaccga tgaaccaggt
    31681 atctatatcg aaggcaaata tggcgttcgt atcgaggatg atatcctgat tacagagaca
    31741 ggttgtgaat tattgaccct agctccaaaa gagttgatag tcatttagtt gtttgtcaag
    31801 aaaaaagtac gaaaatgacg aaaaaagtca aaaaaaatta aaaataggtc gcaagtcgga
    31861 tgttttttat ggtataatag actaaactga tagtaacatg tagcgaaagg ggtaggtaca
    31921 tgattaaaat ttatacagtc tcaagttgta ctagctgtaa aaaagcaaaa acctggctca
    31981 atgcccacca gttaagttat aaagaacaaa accttggtaa agaaggaatt acgagagaag
    32041 aattactgga tattctaacc aaaacagata acggaatagc cagcatcgtt tcgtctaaaa
    32101 atcgctatgc caaagccctt ggagtggata ttgaagattt gagtgtcaat gaagttctca
    32161 atctgattat ggaaacaccg agaattttaa agagcccaat ccttgtagat gaaaaacgcc
    32221 tgcaagttgg ctacaaggaa gacgatattc gtgccttcct accacgctct gtccgtaatg
    32281 tagaaaatgc agaagcacgt ttgcgtgcag ctctataaac atcaaggctg ggagcacttc
    32341 ccagtcttat tctattttaa tttcaaaaag aaagaagaaa gaaatgaaaa aaatagttct
    32401 tgttagtcta gctttccttt ttgtcctggt tggttgcgga cagaaaaaag aaactggacc
    32461 agctacaaaa acagaaaaag atacgcttca gtcggcattg ccagttattg aaaatgctga
    32521 gaagaataca gttgtaacta agactttggt cttgcccaag tcagatgatg gtagccagca
    32581 gacacaaaca attacttaca aagacaagac ttttttgagt ctaactatcc aacaaaaacg
    32641 tccagtctct gatgagttga agacttatat tgaccaacat ggagtggagg aaactcaaaa
    32701 agctcttctt gaagcggagg agaaggataa gtctatcatt gaagctcgta aattggcagg
    32761 tttcaaactt gaaacaaaac tattgagcgc aacggaactt caaacaacga ctagttttga
    32821 ttttcaagtt ctggatgtca agaaggcttc ccagttggaa catctgaaga atattggttt
    32881 ggaaaatctt ttgaaaaatg aaccaagcaa atatatttca gatagattgg caaatggcgc
    32941 gacagaacaa tagaaaatcc aaataaatag actgcctgaa ttgtagaagg taaggaatta
    33001 tgctataatg gtactattct aaggaaagag ggtgttagaa tgggatttac tgaagaaaca
    33061 gtacgtttta aattggacga ttccaataaa aaagaaatta gcgaaacttt gacagatgtt
    33121 tatgcttcgt tgaacgataa gggttacaac ccaattaacc aaatcgtagg ttacgtattg
    33181 agtggagacc ctgcctacgt tcctcgttat aataatgcac gaaatcaaat ccgtaagtat
    33241 gagcgtgatg aaatcgttga ggaattggtt cgctactacc tcaaaggaca aggagtcgat
    33301 ctataaccta tgagaattat gggattggac gtcggttcaa aaacggtagg ggtggcgatt
    33361 agcgatccgc ttggttttac agctcaaggg cttgaaatca tccagataaa tgaagaacaa
    33421 ggccaatttg gttttgaccg cgttaaggaa ttggttgata cttacaaggt ggaacgattt
    33481 gtagtgggct tgcctaaaaa catgaacaat acaagtggac cgcgcgtaga agctagtcaa
    33541 gcctacggag caaagctaga agagtttttt ggtttaccag tagactatca ggatgaacgc
    33601 ttgacaacag tggctgctga gcgcatgttg attgaacaag cagatatcag tcgcaataag
    33661 cgcaagaaag tcattgataa gttagcagct cagctgattt tacaaaatta tttagataga
    33721 aaattttaat ataaaggaga ggctatgtca cacgatcata accacgacca cgaagaacgt
    33781 gaactaatca cactagtaga tgagcaagga aatgaaacct tgtttgaaat ccttttgaca
    33841 attgatggaa aagaagaatt tggtaaaaac tatgttcttc tagtaccagt taacgcagaa
    33901 gaagacgaag acggacaagt tgaaatccaa gcttactcat tcatcgaaaa cgaagatgga
    33961 acagaaggcg aattgcaacc aatcccagaa gactcagaag acgaatggaa catgattgaa
    34021 gaagtcttca acagctttat ggaggagtaa aaacgtccgg gggacgtttt tagccctgcg
    34081 ctagaaatta gaaacgcagg tagtctggga gactgtatca gcccaactcc cagaaatggg
    34141 gaagagttgg aacgtccagt gaacattttt accccaactc ttagaaattg agaagagttg
    34201 gaacatctag tggatgtttt tagcccatat tcacattcat agtggctagt tattagctaa
    34261 ccaggtaaga ggtcgggacg aaaatcctgg ccttgttttt attagtaacc atactttaat
    34321 gcgataattg attggacttt tgtcaaggag atgtgtatgt ttgaagtaga agaatggctc
    34381 catagtcgga ttggtttaaa ttttcgatca ggtttgggcc gaatgcagca agcggtggat
    34441 ttgttaggaa atcctgagca gtcttaccct attatccacg taacagggac taatgggaaa
    34501 ggatctacca ttgcttttat gagggaatta tttatggggc atggcaaaaa agttgcgacc
    34561 tttacctccc ctcatatcgt ctctatcaat gaccgaatct gcattaatgg gcaacctata
    34621 gcagacgcag actttatccg tttggctgat caggtcaagg agatggagaa aacgcttctg
    34681 caaactcctg accagttgtc cttttttgaa ttgctgacct tggttgcttt tctttatttt
    34741 agggagcaag aggtggattt ggttttatta gaagtgggaa ttggtggctt acttgacacg
    34801 accaatgtgg taactggaga gcttgctgtc atcacctcca ttgggcttga ccatcaagaa
    34861 accttgggtg atagtctaga agcaattgca gagcagaaag ctggtatttt caaggctggt
    34921 aagaaggcag tgattgcgaa attgcctcca gaagctaggc ttgtctgtca gaaaaaagcc
    34981 gaatctttag ctgttaacct ttatcaggca ggtcaagatt ttttaatgct gaatggtgat
    35041 ttttcaagct ctttactaaa tctttcacag ctgaacatag gcttagaagg agtctatcag
    35101 caggagaatg cagccttggc gttgcaaact tttcttcttt ttatgggaga aggaaaggaa
    35161 gctgttgatg aacaggctgt aagaaaggcc ttggaacaga cccattgggc tggtcgcttg
    35221 gagcgtattc gcccacagat ttacttggat ggtgctcata acctccctgc cttgactcgc
    35281 ttggttgagt ttatcaaaga aaaagagcag gaaggctatc gacctcaaat cctttttgga
    35341 gccttgaaac ggaaggatta tcaagggatg ttaggttacc tgactgaaaa attgcctcag
    35401 gtggaactca aggtgaccgg ctttgactat cagggggctt tggacgaaag ggatgtgaca
    35461 ggttacgata tagtttcttc ttgccgagaa tttatcagcg attttgaaga aagagcagat
    35521 gctcaggatt tgctgttcgt tacagggtct ctctatttta tctcagaagt acggggctac
    35581 ctgctggacc gtgagcagat aaattgaccc ccttgtttga acttgttata ctaggggaat
    35641 tgctggttag agaaaatttc tctaaattgg tagcagaaag gaaattcatc atgaaattaa
    35701 aaagattcac actttctctt gcttctctag caagttttag tctcttagta gcttgttcac
    35761 aaagagctca acaggttcaa cagcctgttg ctcagcagca ggtccaacag cctgctcaac
    35821 aacctgctca acagaatacc aatactgcaa atgcaggagg taaccaaaat caagcggctc
    35881 cagtacaaaa ccaacctgtt gctcaaccga ccgatattga tgggacttat actggtcagg
    35941 atgacggaga ccgtatcact ttagtggtaa ctggaacgac tggtacatgg actgagctcg
    36001 aatctgacgg ggatcagaaa gtcaaacagg ttacatttga ttcagcaaat caacgcatga
    36061 ttattggcga tgatgtcaaa atttacactg taaacggtaa tcaaatcgtc gtagatgata
    36121 tggatagaga cccatcggac caaatcgttt taactaaata agactatgca agtagaaagg
    36181 gctggatttt tcagcctttt tacttttacc tagaaaataa tcataaatac ttgccttcta
    36241 ccgaatacct gcgttatact agtatcaatt acttgttttt agcattcaaa ctatcaagga
    36301 ggggatatga aatataggaa atttcaatta ttgatgtcca agtatggctt tagtctttcg
    36361 attatgttac ttgaactttg tcttgttttt ggtctctttc tttatttagg acgcatggct
    36421 cccattttat ggattactgt cctcattcta ctgagtatca tcacaatcat ttcgatagtc
    36481 aaccgtaata cgactcctga gaataaggta acctggttgt tagtagcctt tgtgccagta
    36541 tttggtccct tgctctatct gatgtttggt gaaaggcgat tgtccaaaaa agaaatcaaa
    36601 caactgaaga agctaggctc tatgcatttc caagaagcaa atagccagct actaaaagag
    36661 aaattaaaag aaagtgacaa ggcagcttat ggagtcatca agtccttatt gagtatggat
    36721 accaatgctg acatctatga tcaaactgcc tctacatttt ttcctaacgg agaagctatg
    36781 tggaaaaaga tggtagaaga tcttaaaaag gctgagaaat ttattttctt ggaatattac
    36841 attatagaag aaggtttgat gtggaatcgc atactagata tactagagca aaaggtagct
    36901 cagggtgtag aggttaagat gctctatgat gatatcggct gtatggctac tttaacagga
    36961 gattatgcac atcgacttcg tcagctgggc atcgaggccc ataaattcaa taaagttatt
    37021 cctcgtttga cagtggctta taataacaga gatcatagaa aaatattgat tgttgatggt
    37081 cagatagcct atactggtgg gatcaatctg gcagatgagt acattaacca cgtcgagaga
    37141 tttggttatt ggaaggatag tggaattcgc ttagacggac tagcagtaaa agctctgaca
    37201 cgcttatttt tgaccacttg gtacattaat cgaggagaaa ttagtgattt tgatcaatat
    37261 catttagaaa atcattctat cccgagtgac ggtttaacca ttccatacgg aagtggaccc
    37321 aagccaattt ttcgagcgca ggtagggaaa aaagtttatc agagtttaat caatcaagca
    37381 acagaatcgg tctatattac gacaccttat ttgattatag attatgattt aacagagaca
    37441 atcaaaaatg cagctatgag aggggtcgat gttcgaatta tcacccctta cataccagat
    37501 aagaagttca ttcagttagt cacgagagga gcttatcccg accttctttc tgctggtgtt
    37561 cggatttatg agtatagtcc aggttttatt catagtaagc agatgttggt agacgaagat
    37621 tttgcggtgg tggggacaat caatctcgac taccggagct tggtacacca ttatgaaaat
    37681 gcagtcttac tctataaaac tccttctata agggaaatcg cccgagattt tcgaaatata
    37741 tttgcagatt ctcaggaagt ctatcctcat tctatcaaaa cgagctggta tcaaaagctt
    37801 gtaaaagaaa tcgcccagct attcgcccct atcttataag aaatctagaa cttaggatac
    37861 aaaccagacc tatttttctt gtcttttacg aatagaaaga aagaggaggg gaattcatgc
    37921 taactaagga agaagtgaat gatatgattg agttcaaaca gatacattta caccgctttc
    37981 gggaaattga aacctttgtg aaactatgca aaaaatcact caaacagcca tcgcaagctg
    38041 acaatcctag gactttttga tatactaaga cagataaatt gaacaggaga aacgatatga
    38101 gtgtgtatgg tagagtagaa gaagttcata aggagaatcg tgaacctcta gaataccaaa
    38161 tcgaacaaga atcgcatcat cgtgaatcaa gtcgtcttcc tttggtgaaa attttactat
    38221 ggagtacgct tgtaacgggg ataactctag gagtaccgct attactcgac ttaatgagtg
    38281 cacaagaagt gcaggatttt tatgcaggtt gggcgcttca tcagacaggg aagatttaca
    38341 gcgactatta tggaagtcaa ggtttgcttt attatttgct gacttacgtg agtcagggcg
    38401 gatttttctt tgccatcttt gagtggttag ccttggtagc aggaggattt ttccttttta
    38461 gatcagcgga caccttgaca gagcaaggag accaagctgg acatctggtg actatttttt
    38521 acatgctagt tacaggtctt gcttttggtg gaggctatgc gactctttta gcgcttcctt
    38581 tcttattcgc agcctttagt ttagttgcgg cttacctaag caatccaagc catgataagg
    38641 gatttgtacg gattgggcta gctttggcag gcggattttt ctttgctccc ttatcatcgc
    38701 tcctgtttat tgctgtagtg agtttaggct tgttggtctt taaccttggg catagacgct
    38761 ttgcgcatgg gttttatcag tttcttgcag tggctttagg tttttcactt gtcttttatc
    38821 caactgccta ctatagtgct gcaacaggaa gttttgggga tgcgattagt ggtattcgtt
    38881 atcctattga cagtattcgc tttgatttta cttctaaaat tttagagaat atgttttttt
    38941 atggcttgtt gtcccttggt ttgggatttg tggtttgtat ctttttaggt ctctttcaat
    39001 ccaaaccctt taaactatac gtcatttcgg ttcctgcaag tcttgtggta attttaggtt
    39061 tgattttact tttcttttca caagagcctc tgcacgcttc ttatttgatg gtcgtcttcc
    39121 ctgttttcct acttttattg gtaaccaata ttaagagtca acagaggggg cgtagtgcta
    39181 gaagaagccg aagagaaacg ccagttagcc tatggagtcg tttcttcaaa ggaaatctat
    39241 atctgctagt ttttgagttt gtctatcttt tgtctgttcc ttttttgatg aagtttgtcc
    39301 tttatccagt accttatcaa gaacgtaatc gtcttgctga tttggtaaaa gaggagacaa
    39361 atacggaaga tgctatctat gcatgggatg atactgcgac tctttatcgt aagagtgagc
    39421 gcttgtcgcc atcggcgatt ttgtccccgt tgcactatac agcaactgag gaaaatcgta
    39481 ataagttact taatgacttg aaagaaaaac aacctaaggt gattgtggta aatgataagg
    39541 tggtagtctg gtctgaagtg gaaacactct taaaagaaaa ttaccaacaa gtaaagactg
    39601 attactcaga gtttaaagtc tataaaatta aataaccaaa tcaatatctt gtgtattttt
    39661 aaaaatttta ggatttttaa cacaagatat tgatttttct ttttagagtg gtataatact
    39721 ttttagaaag aacattttag aaaagagcat gcatatgatt gcactagaag aaaaaattac
    39781 aattttgcca actctcttcg tcgagaaacg agatgggaga cgtgttgtat ttgatgtgga
    39841 caagattgac aaggctctcc acaaggcggc tgacaaggtt atggatgtga cacccctggt
    39901 tgaaaaacgc ctcaatgatc tgactgagcg aattattaca gaaattcata gtcgctttcc
    39961 acagggaatt aagatttacg aaattcaaaa tatcgtagaa catgaactcc ttgaagccaa
    40021 agaatatgcg ctggctgagg agtatattac ttatcggaca cagagggatt ttgagcgctc
    40081 aaaagcgacg gatatcaact ttagtattca taaacttctc aacaaagacc agacagttgt
    40141 caatgaaaac gctaataaag acagtgatgt ctttaacact cagcgtgatt tgacagcagg
    40201 gattgttggg aaatcaatcg gactgcaaat gcttcctaag cacgtagcca atgcccacca
    40261 aaagggggat atccactatc acgatttgga ctacagtccc tataccccta tgaccaactg
    40321 ctgtttgatt gattttaagg gtatgttgga aaatggtttt aagattggaa atgcagaggt
    40381 agagagtccc aagtctatcc agactgcgac agcacagatt tctcaaatca ttgccaacgt
    40441 tgcttctagc cagtacggtg gctgttcagc tgaccgtatc gatgaaattt tggcgcctta
    40501 tgcagagaag aattatcaaa aacatctcaa agatgcagaa gagtgggtat tgcctgaaaa
    40561 acgggaagat tacgcttgga agaaaacgca aaaggacatc tacgatgcca tgcaatctct
    40621 tgagtatgaa atcaatactc tcttcacttc aaatggacaa acacctttta cttcgttagg
    40681 ttttggtctg ggaaccagtc gttttgaacg agaaattcaa aaagctattt taaacattcg
    40741 catcaagggt cttggttcag aacaccgtac ggctatcttt cctaaactta ttttcactct
    40801 gaaaagaggc cttaatttag aggaaggaac tcccaactac gacatcaagc agttggctct
    40861 tgagtgtgca accaaacgga tgtatccaga tgttttatct tacgataaga ttgttgactt
    40921 gacaggatcc ttcaaggtgc ctatgggttg ccgttctttc ctccaaggat ggaaggatga
    40981 aaatggtgta gaagtcaatt caggtcgcat gaatctgggt gttgtgacgg ttaatctgcc
    41041 tcgtattgct cttgagtctg aaggtgatat gaataagttc tgggaaatct tcaacgagcg
    41101 aatgaatatc gcagaagatg ctcttgttta ccgtgtcgaa cgcactaaag aggcgacacc
    41161 agcgaatgct cctatccttt atcagtacgg tgcttttggc catcatctag gtaaagaaga
    41221 aagtgttgac cagctcttta agaatcgtcg tgcgaccgtt tcgctgggct atatcggctt
    41281 gtatgaagta gcgacagttt tctttggtaa cagctgggaa agtaatccag atgctaagga
    41341 attcacgcta gacatcattc acgatatgaa acgccgtgta gaagagtggt cagaccaata
    41401 tggctaccat ttctctatct actcaacacc atccgaaagt ctgacagacc gtttctgccg
    41461 actagatata gacaagtttg gctctattcc tgatatcaca gacaaggaat actacaccaa
    41521 ctctttccac tacgatgttc gtaaaaatcc aacaccgttt gaaaaattgg actttgaaaa
    41581 agtctatcca gaagcaggtg cgtcaggtgg tttcatccat tattgtgagt atccagtcct
    41641 tcagcaaaat ccaaaggcct tggaagctgt ctgggattat gcttatgacc gtgtaggcta
    41701 tctaggcacc aatactccga ttgaccgttg ctacaagtgt gactttgaag gggattttga
    41761 accaactgag agagggtttg cttgtccaaa ctgtggcaat agcgacccta aaacagtaga
    41821 tgtggtgaag cgaacttgtg gctacctagg taatcctcaa gcaagaccga tggtcaacgg
    41881 gcgtcacaag gaaatcgctg cgcgtgtcaa acatatgaat ggttcaacga ttaaaatagc
    41941 tgggcatcaa gtaacaaatt agaaagaaat gaaatgggaa aatatcaact agacgataag
    42001 gggcgcgcac aagtgacccg ttatcacgag aagcactcta aaggtggagc tggtaagaaa
    42061 gaacgcttgc ttagcttcag agaacaattt ttaaacaaga acaagaaaaa ataaaagtga
    42121 gagccagctc tcgcttttct catagtggga ggtaaggatg gaattacgca gaccaagatt
    42181 agcggataag aaagctgttt tagatatgat gacagagttt gaaaagagcc aatcagccca
    42241 tgatggagga ttttgggatg ttgaggattt ttcttacgag gagtggctag aaggtaaccg
    42301 taataaagaa atgggaatat ggctacctga aaatcgcgtt ccatcgatac agttcgtatt
    42361 gtttggtgaa tcaggttgtg ctctaggatt tttgaatctg cgattgagac tgaatgaggg
    42421 gttactgaat tatgctggcc acattggcta ctccatccgt ccatctgaaa gaggcaaggg
    42481 ttatgcaaaa gagactctcc gtcagggctt gcaagttgct aaggaaaaga acatcaagaa
    42541 agctctggtg acctgtagcg tgaataatct tgctagtaga gcagtcattc tagcaaatgg
    42601 tggaatattt gaggatgctc gcaatggagt cgagcgttat tggatagagg tagcgaatga
    42661 ataatccaaa accacaagaa tggaaaagcg aggaacttag tcaaggtcgt atcattgact
    42721 acaaggcctt taactttgtg gacggcgaag gcgtgcgtaa ctctctctat gtatcaggct
    42781 gtatgtttca ctgcgaggga tgttataatg ttgcgacttg gtcttttaat gctggcattc
    42841 cctatacagc agaattagaa gagcagatca tggcagatct tgctcagccc tatgttcaag
    42901 gtttgacttt gttgggaggg gagccttttc ttaatactgg gattctcttg ccacttgtta
    42961 agcggattcg gaaggaattg ccagacaagg acatctggtc ctggaccggc tacacttggg
    43021 aagaaatgat gttggaaact ccagataaac tggaattctt gtcactgatt gacattcttg
    43081 tcgatggaag atatgatcga actaagagaa atcttatgct ccagtttcga ggttcgtcta
    43141 accaacgaat tatcgatgtg caaaaatcgc tcaaaagtgg gcaagtagtg atttgggaca
    43201 agctcaatga cggaaaagaa agctatgaac aggtgaagag agaatgaaga aaaaagactt
    43261 agtagaccaa ctagtctcag agatcgagac ggggaaagtc aggacactgg gaatatacgg
    43321 tcatggagct tcaggtaaat caacctttgc acaggaattg taccaagctt tagattctac
    43381 tacagtaaat ttgctagaga cagatcctta tatcacctca ggacgccatc tggtagtacc
    43441 caaggacgcg ccgaatcaaa aggtgacagc cagtctgcca gtggcgcatg aactggagag
    43501 tttgcagaga gatatccttg ccttgcaggc gagtatggat gtcttgacaa ttgaagaacc
    43561 ttggaaggct agtgaggtct tgtctggagc caaaccaatt ttgattgtcg aagggatgtc
    43621 tgttggcttt ctacccaagg aactctttga aaaaaccatc tgtttctaca cggatgagga
    43681 gaccgaatta aagcgacgcc ttgctagaga tacgactgtg agaaatcgcg atgcatcctt
    43741 tatattggct agccatcaga tgagacggga gcagtatctg cgatactata aagaaactga
    43801 gtctaaggcg gatatcttag tggaccaatc agaagataaa tttgatgtca agaggactta
    43861 acttatgtat agaagaaata tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa
    43921 acagtttcat ccccaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt
    43981 gtgttattct attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac
    44041 acgctcggtt gcattgccac gcaacaccgc gtcggttttc ttgtggagct agcctattat
    44101 cttaaataga cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag
    44161 cttacgaaca ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta
    44221 caggtgcaca agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca
    44281 ttcgtgcgac tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac
    44341 gtttgatcga tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc
    44401 ttccaagtgg tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct
    44461 ggtgtttcaa tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc
    44521 gtctgctaga cactgtgtca gtttcctatt ttcacgttga gtttgacgcc ctttgtatct
    44581 tagacttgag cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga
    44641 actattttct catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca
    44701 ctgaagctgg cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc
    44761 aagttaaaac tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac
    44821 gcgaagtatt gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta
    44881 agcgcttcat tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag
    44941 ttgaaacatt cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt
    45001 tccaaggtgt tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt
    45061 accaccgtcg tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa
    45121 accttgcagg acgtatgggt ggtgaccgcg taacaattca aaatcttgaa gttgtacaag
    45181 ttgttccaga aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc
    45241 ttatcactat caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca
    45301 caatggcaaa cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta
    45361 gcgatgcagt atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc
    45421 aacgcgcaag ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg
    45481 gtggacgcaa accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct
    45541 caccacaatg gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca
    45601 aacttccaca aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg
    45661 aaaacaaatt cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg
    45721 caaaagttct tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa
    45781 atgaattcgc agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa
    45841 ctgcaagtgt tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct
    45901 ctaaaatcga ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat
    45961 cactgaaagc tcaatggctc aacttgaagc agggaaatat gtatttgaag ttgacactcg
    46021 tgcacacaaa cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc
    46081 caatgttaac acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt
    46141 tactaacaaa actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt
    46201 gtttgctgct gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa
    46261 ccaacaacaa acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc
    46321 actcctgaaa aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt
    46381 cgtatcacag ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc
    46441 aaacgtaata aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt
    46501 tctgcaaaca tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca
    46561 aaaggtcttg aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga
    46621 aacgctcttc cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa
    46681 ccaggtcgtg gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct
    46741 gaaggtaaat acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact
    46801 tgccgtgcta cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa
    46861 gcaggacgta gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct
    46921 aacgatcacc cacacggtgg tggtgaaggt aaggcaccag ttggtcgtaa agcaccatct
    46981 actccatggg gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac
    47041 aaacttatcg ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag
    47101 taaatccgcc agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa
    47161 aggagaaaat ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt
    47221 gatgaaaaaa gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc
    47281 acgtcgatca acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg
    47341 taaacacgta cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc
    47401 accaactcgt acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg
    47461 agaacataaa tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca
    47521 cctcgtaaat cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc
    47581 gcaatcttga cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca
    47641 gctgtagcta acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa
    47701 gcattcgcaa acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct
    47761 tcaccaatca acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt
    47821 aaaatcgtgg gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg
    47881 gatgccaaat ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc
    47941 cgtaaattcg ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc
    48001 gcagtaaaca aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa
    48061 ggtggtgcta acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta
    48121 cacatcaaca tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga
    48181 attgctcgtc aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa
    48241 cgtgcaatgc gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt
    48301 gcagatatcg cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt
    48361 gcagatatcg attacgcttg ggaagaagca gatactacat atggtaaact tggtgttaaa
    48421 gtatggatct accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa
    48481 ccaatgttag tacctaaacg tgttaaacac cgtcgtgaat tccgtggaaa aatgcgcggt
    48541 gaagcaaaag gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc
    48601 cactggatca ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa
    48661 cgtggtggta aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc
    48721 ggtgtgcgta tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt
    48781 ggtaaagtga tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga
    48841 cttgctagcc acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga
    48901 gaaggcatga aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa
    48961 gaagaactcg cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa
    49021 gctgctactg gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct
    49081 cgtatcaaaa cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg
    49141 gaacgcaata atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca
    49201 atcacagttg tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac
    49261 tctaaaaaat acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt
    49321 atcatggaaa ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa
    49381 gaagcggtca tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac
    49441 tcgtttgaaa gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg
    49501 tggttcagga cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc
    49561 tactcctggt ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa
    49621 atcaggtgct cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat
    49681 catccgtgaa gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt
    49741 gcgtgaaggt ggtttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg
    49801 aacaaactag tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg
    49861 agaaacctaa tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagataag
    49921 ggaacagaag ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt
    49981 gttaacattg ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc
    50041 gagaaagaag cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct
    50101 ggtcgtgttg gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc
    50161 gaagtgcttg attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa
    50221 aatatcttaa tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg
    50281 ctgtgcctaa agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg
    50341 ctaaaagcct tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta
    50401 tcactaaagc taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg
    50461 caaaagttac ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt
    50521 cacttccgcg tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga
    50581 actacacact tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg
    50641 acaaaactcg tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac
    50701 gtgcattgct tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat
    50761 ggctaaaaaa tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc
    50821 tgaaaaacgt gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg
    50881 caacgcctca ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt
    50941 ttaccgcaaa tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat
    51001 tcctggtgta acaaaagcat cttggtaatt taagatatca agagtgtcaa aactccaagt
    51061 aaaaatagga aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca
    51121 gagtttagcc cgggttcaat tgggcttgcc aatttgaaca cgagctacag ctttggcaaa
    51181 aaagaccaat ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct
    51241 gttacgctct ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag
    51301 gagaaaaaca aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat
    51361 gctaaccaag ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt
    51421 gctgaaatcc ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa
    51481 caaggcgtca tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac
    51541 ttgaaacgtg tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa
    51601 gttcttaacg gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa
    51661 gaagcacgcc aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat
    51721 acaaagctcg taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag
    51781 ccaacttatc tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata
    51841 agtatctgaa ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa
    51901 acatgtcacg tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca
    51961 atgacaacgt tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag
    52021 atattgaaat ccgtgtggaa ggtactgaaa taactcttca ccgtccaaac gattcaaaag
    52081 aaatgaaaac tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat
    52141 cagaaggatt caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag
    52201 gatctaaact tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag
    52261 gaattacttt tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag
    52321 tagttggtca aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta
    52381 aaggtatccg ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat
    52441 gttgagtggt tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt
    52501 taaaactaaa gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa
    52561 acgccaccgt cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt
    52621 attccgttct aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct
    52681 cgcaagtgct tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt
    52741 tgctgtcggt aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt
    52801 cgaccgcggt ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga
    52861 aaacggattg aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt
    52921 gaattagaag aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt
    52981 cgtcttcgtt tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt
    53041 actggtaaag ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa
    53101 aacttgatcg aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc
    53161 ggtggagcta aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt
    53221 gcagttcgtg ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt
    53281 tctaacactc caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc
    53341 gctgaagaaa ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga
    53401 taaaatggct caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca
    53461 acgtaaaact gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga
    53521 taacgctgct atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt
    53581 aaactaatga agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat
    53641 ctatgatgac atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg
    53701 ctagcatttt acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga
    53761 aggttctcgt aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac
    53821 atctggtcgt ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt
    53881 tgaaggtgga caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa
    53941 cgctaaagaa tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga
    54001 agtaactcca gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa
    54061 aattcttggt aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa
    54121 atcagctgaa gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg
    54181 acctatgttt tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat
    54241 tttatttaca atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg
    54301 tgtgaatgcc aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt
    54361 ggtgtcgggg aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat
    54421 cactgcttct attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg
    54481 gggtaaacaa ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct
    54541 agttctcgct tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc
    54601 tcaattgatt aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac
    54661 agctggtagt atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa
    54721 cggtgtttcc atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg
    54781 catctatgtg gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt
    54841 cgtaatcatt ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca
    54901 agcagaatac aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc
    54961 ttaccttccg ttaaaggtaa atcctgctgg agttatccct gttatctttg ccagttcgat
    55021 tactgcagcg cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg
    55081 ggtaagggta gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc
    55141 tttgttgatt attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc
    55201 agcagagagc ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac
    55261 agaagaatat atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg
    55321 tgtgatttcc attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc
    55381 ctttggtgga acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt
    55441 ggaaggttac ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta
    55501 tttactgaat cagtaaatgc tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt
    55561 ggatctcccc tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt
    55621 aaaaataaaa taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg
    55681 taagggaact caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg
    55741 tgatatgttc cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata
    55801 tattgacaag ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct
    55861 ttcacaagat gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga
    55921 acaagctcat gccttggaca aaacattggc tgaacttggc attgaactag aaggtgttat
    55981 caatattgaa gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg
    56041 cgtaactgga gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga
    56101 ttactaccaa cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat
    56161 tgctcaagga gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga
    56221 aggtaatcaa gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa
    56281 ataaagcgtt tttcatactt gcaaaaattc gctacaaatg ttatactgag atagtctgac
    56341 ttataattgt tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc
    56401 gtggcaaaag acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca
    56461 atgtttacgg ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt
    56521 cgtaaaaact atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat
    56581 gacttgacac gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa
    56641 gaaatgaaag taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt
    56701 aatggtcgtg ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa
    56761 gatagaaagg agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg
    56821 tagtaatctc attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg
    56881 ctgctgctgg aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg
    56941 ctatccgtcg tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact
    57001 tgaacatcaa acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac
    57061 ttcctgtccg tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg
    57121 cgattgctgg taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa
    57181 acgtcgtgtg aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa
    57241 cactattgtt atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc
    57301 tcttggtttc aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc
    57361 tgctgctaaa tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc
    57421 aggttctggt cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc
    57481 aattcgtgat gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt
    57541 ataatcatcg cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga
    57601 aaaaccaaat ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc
    57661 acttgaacgt ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc
    57721 tctaccagga gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac
    57781 agttccaggt gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt
    57841 gaaatcgtac gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt
    57901 aacagctggt gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct
    57961 ctttacaatc ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg
    58021 atatgtacct gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga
    58081 ttctatttat acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag
    58141 caatgatggt ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga
    58201 agatgcttta gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct
    58261 tactgagatt gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg
    58321 tattttagat cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa
    58381 acgtgccggt atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa
    58441 agtacgaaat cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg
    58501 tcttggatta aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact
    58561 agctcacaac gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca
    58621 atcgtgacaa ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact
    58681 ctaggtaaac gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa
    58741 atcgcatctg aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa
    58801 aaattgttct cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc
    58861 cttaaaactg aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa
    58921 aatcatcaat tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg
    58981 tctaccgcta ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc
    59041 ttgtttacga aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt
    59101 ttcgttagaa ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat
    59161 tttaagaaga attggagttt acttatgaaa gcgattataa ctgttgttgg taaagataaa
    59221 tctggaattg ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat
    59281 atctctcaaa ctgtattgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa
    59341 aagcaagatt ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta
    59401 aaaatcaata ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc
    59461 atggatatta gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt
    59521 agaaccatta ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct
    59581 gcggagaaaa tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat
    59641 gaaattgcgg ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt
    59701 tctctgattg gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat
    59761 aaggctgcga aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa
    59821 ggttatcaaa agggagatga gattctcatc aattccattc ctcgcgcttt gactgagacg
    59881 gataaggtct gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct
    59941 gtggcagata tgggacgaat tatcaaggaa acggcaaatc tttcagatat gggagcggct
    60001 aagttggttg tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat
    60061 ggtgttgggg aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa
    60121 cgtgctttgg aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa
    60181 actgccttta aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg
    60241 ggtgtggagt ttggtattgt ggacttgagt ttggcaccaa cccctgcgat tggagactct
    60301 gtggcacgtg tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacggtt
    60361 gccttggccc tcttgaacga ccaagttaaa aagggtggag tgatggcctg caaccaagtc
    60421 ggtggtttat ctggcgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg
    60481 caaaatggct ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga
    60541 ttggatatga ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg
    60601 gatgaagcag caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa
    60661 ggaagagaag gcgatatgat tgagtttggt ggtctattag gaactgcacc tgttatgaag
    60721 gttaatgggg cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt
    60781 catagtttta aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg
    60841 tatactataa tcattaaata aagacctcct aatattattt gaaacagata acactgaatt
    60901 agtttgaatt tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa
    60961 taatctcctt caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata
    61021 gaagcaaacg gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag
    61081 accatgttta acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa
    61141 ggtgaacgag ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag
    61201 cgcgcttatt cgagtgattc tggtcgtacc attcagacca tgggaattat ccttgaagaa
    61261 cttggcttgc aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc
    61321 ggtagttttg atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt
    61381 aatgtggacc acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc
    61441 gatacagctg gttgggctga aggctgggaa aaactcagtg gccgaatcaa ggaaggcttt
    61501 gaaatgattg caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat
    61561 ggaatgacta ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat
    61621 aatggtagcg tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt
    61681 gaccgtagtt accgagagct aggatgtgag aagatggaag aaggctctat ttaatcagtc
    61741 tagacttgct tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc
    61801 gagggcactc ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt
    61861 agagattttc ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa
    61921 ggctgcggct acaccgtaat ttcctctgag aacctctgta taaatagcta cagtcattgt
    61981 tcttgttttg acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca
    62041 agataagatg gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa
    62101 ggtattgaga cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg
    62161 ttgtaagcta gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat
    62221 aatcaagatg aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt
    62281 gaaggaagaa atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact
    62341 gaggctgtca attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa
    62401 tgtcgcaaat agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat
    62461 agcagatccc atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaga
    62521 taccatacct gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga
    62581 gataaagata attccgtaga ctgttgcata aatggcagct atttttcctt ttgtagtttt
    62641 tttaggctca attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt
    62701 ttggataagg aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc
    62761 tccaacctcg ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgtc
    62821 aatcaacata ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct
    62881 agtaaggttg gaactaggag aggtaaaaca accgttacga tacgcttaaa tccgaaggac
    62941 cccatgcttt cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca
    63001 tatagaaata ccagtgggaa tagttgcagt gtaaagacaa gtacaattcc tttgaatcca
    63061 taaatatcga tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt
    63121 cgtcccagca agagaattca ggagtaggct cctacgaaag gagctgacat ggaagcaatg
    63181 ataatcaata tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct
    63241 aatagggttc ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg
    63301 actagtgtct cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat
    63361 tatccttcat gtataagtgc ttacttgagc acggtaacga taggataaac gagaaagaca
    63421 agataggtaa gaaagaggag gctgtccaaa tatttagttt tttacgttcc atggttgact
    63481 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    63541 cgtagacgaa tacgattgtc tttttgtaga tcttcttcaa aagttgattc ttcactaact
    63601 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg
    63661 ctatcgctaa tagttccttc gatatctcca gattcatctt tgataaactc ttcgggacga
    63721 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctagcattcg aagggcatag
    63781 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    63841 tttgtgcgtc cgataaaggt tgccacaaac tcattagttg gtttatgata gagttctttt
    63901 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    63961 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    64021 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    64081 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    64141 tgtccaccac tgagtttatc gggctttcga tccgcatatt gagcaatttg catgagttca
    64201 agatacttgt tggtctgttg aatcaattct tcttttggaa ccttcttttg cataagacca
    64261 aaagcaacgt tgtctcggac agtcaaatgt gggaaaatag cgtagttttg gaaaaccatc
    64321 ccgatattgc gtttgctggg ttccatatta ttgatttttg tatcatcgaa gtaaaattct
    64381 ccaccttcga tactgttgaa acctgcaatc atacgaagaa gggtcgtttt cccacatcct
    64441 gaagctccaa gaagggtaaa gagacttcct tttggaattg taatgttcaa attctcaata
    64501 acagggacat cgtggtagat ttttttggcg ttaataattt tgatctcact catagtgaac
    64561 ctcttttact gtttagattg gatatctgta aagacttcgt tgtatttctt aacgatatct
    64621 gatttattct tgatgacata atcataatct tcagtgagtg ttttgatttt gtcaattggt
    64681 ttcatgtttt cgcttgtttt agcattttta cgaacaggac ggttagtagt ggttgtacca
    64741 agtgtatctt gtacttcttg agagataata aaatcgataa atttcttggc attttccata
    64801 tttttagatt ttttaacgat agcagcacta gcaggtagga agacggttcc ttcttttgga
    64861 tagactacct taatgttagc tccgtcattt aagagtttaa ctgctggatc ttcataagag
    64921 agaccaacag tcatttcttc atcagcgact gctttataga caccagatga acttaaaccg
    64981 attttatagt atattgaaac tagaatagta cacatctact tctaaaatat tgttagaaat
    65041 cgatttgact gtcctgatta atttgtcctg ttcttatttc attttactat accatcaata
    65101 agtgtgaaaa gatcttttac ataagaccaa gccttatcat ctttgtaacc accttgagct
    65161 tgtagcatat ttgttaattg agcaaaggtg ctagaagagt ttgctgggtc agcagttgcg
    65221 attttttctt ttagttcagg tttgagaaga tcgttatatc cttcgatgtt catgccttta
    65281 gttaaatcag ggttgacgat taaaacacta ccatctagtg tataaggagt agagaagcca
    65341 gttgtgtttt gatattcttt gataacatta tcattttctt ttgaagtata gttttcaaag
    65401 agttctccgt gggtagcata ttgtgtataa gaaccaccaa agataacatc agctacagga
    65461 acttcttttt ctgactctag ttttttgaaa agttctccag taccagcttg aatcagttct
    65521 actttgatac catatttttc ttcaaaggca ggaatagttg ctccaattaa gtcctctgag
    65581 tttggtcaat aaacgactag cgaaccaccg tctcctttat cagatgaact gtcatcggca
    65641 gattcattag aagaacaagc agcataatac atccatttct ttttcatgat gggatatctc
    65701 cgttgtgtta tttaagttta ttttaaaaaa atgtaagcgt ttttaaa
//
LOCUS       DAVMCN010000005        63363 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVMCN010000005 DAVMCN010000000
VERSION     DAVMCN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.005"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(68..322)
                     /locus_tag="VYP85_000425"
                     /pseudo
     CDS             complement(68..322)
                     /locus_tag="VYP85_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            587..823
                     /locus_tag="VYP85_000426"
     CDS             587..823
                     /locus_tag="VYP85_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1880983.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1054..2340
                     /locus_tag="VYP85_000427"
     CDS             1054..2340
                     /locus_tag="VYP85_000427"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1880984.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            2541..3008
                     /locus_tag="VYP85_000428"
     CDS             2541..3008
                     /locus_tag="VYP85_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1880985.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            3041..3134
                     /gene="ffs"
                     /locus_tag="VYP85_000429"
     ncRNA           3041..3134
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYP85_000429"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            3194..3637
                     /locus_tag="VYP85_000430"
     CDS             3194..3637
                     /locus_tag="VYP85_000430"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1880986.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            3639..4154
                     /locus_tag="VYP85_000431"
     CDS             3639..4154
                     /locus_tag="VYP85_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1880987.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            4168..5529
                     /gene="radA"
                     /locus_tag="VYP85_000432"
     CDS             4168..5529
                     /gene="radA"
                     /locus_tag="VYP85_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1880988.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLQQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            5602..6099
                     /locus_tag="VYP85_000433"
     CDS             5602..6099
                     /locus_tag="VYP85_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1880989.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            6124..6333
                     /locus_tag="VYP85_000434"
     CDS             6124..6333
                     /locus_tag="VYP85_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1880990.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            6315..6938
                     /locus_tag="VYP85_000435"
     CDS             6315..6938
                     /locus_tag="VYP85_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1880991.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            7339..7653
                     /locus_tag="VYP85_000436"
     CDS             7339..7653
                     /locus_tag="VYP85_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1880992.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            7669..8055
                     /locus_tag="VYP85_000437"
     CDS             7669..8055
                     /locus_tag="VYP85_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1880993.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            8084..9469
                     /locus_tag="VYP85_000438"
     CDS             8084..9469
                     /locus_tag="VYP85_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1880994.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            9472..9624
                     /locus_tag="VYP85_000439"
     CDS             9472..9624
                     /locus_tag="VYP85_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1880995.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            9647..11065
                     /locus_tag="VYP85_000440"
     CDS             9647..11065
                     /locus_tag="VYP85_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV1880996.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEI
                     RLRSKLKSVLIVHYLKILYNRN"
     gene            11114..11197
                     /locus_tag="VYP85_000441"
     CDS             11114..11197
                     /locus_tag="VYP85_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV1880997.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            11322..12059
                     /gene="erm(B)"
                     /locus_tag="VYP85_000442"
     CDS             11322..12059
                     /gene="erm(B)"
                     /locus_tag="VYP85_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV1880998.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(12316..13563)
                     /locus_tag="VYP85_000443"
     CDS             complement(12316..13563)
                     /locus_tag="VYP85_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1880999.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            13743..13964
                     /locus_tag="VYP85_000444"
     CDS             13743..13964
                     /locus_tag="VYP85_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881000.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            14081..14578
                     /locus_tag="VYP85_000445"
     CDS             14081..14578
                     /locus_tag="VYP85_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV1881001.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            14553..15059
                     /locus_tag="VYP85_000446"
     CDS             14553..15059
                     /locus_tag="VYP85_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1881002.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            15043..17490
                     /locus_tag="VYP85_000447"
     CDS             15043..17490
                     /locus_tag="VYP85_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1881003.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            17493..19670
                     /locus_tag="VYP85_000448"
     CDS             17493..19670
                     /locus_tag="VYP85_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1881004.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            19667..20668
                     /locus_tag="VYP85_000449"
     CDS             19667..20668
                     /locus_tag="VYP85_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV1881005.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            20665..21597
                     /locus_tag="VYP85_000450"
     CDS             20665..21597
                     /locus_tag="VYP85_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1881006.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            21842..21958
                     /locus_tag="VYP85_000451"
     CDS             21842..21958
                     /locus_tag="VYP85_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV1881007.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            21974..23893
                     /gene="tet(M)"
                     /locus_tag="VYP85_000452"
     CDS             21974..23893
                     /gene="tet(M)"
                     /locus_tag="VYP85_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV1881008.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            24012..24179
                     /locus_tag="VYP85_000453"
     CDS             24012..24179
                     /locus_tag="VYP85_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV1881009.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(24239..24592)
                     /locus_tag="VYP85_000454"
     CDS             complement(24239..24592)
                     /locus_tag="VYP85_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1881010.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            25097..25519
                     /locus_tag="VYP85_000455"
     CDS             25097..25519
                     /locus_tag="VYP85_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1881011.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            25516..25746
                     /locus_tag="VYP85_000456"
     CDS             25516..25746
                     /locus_tag="VYP85_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1881012.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            26207..26410
                     /locus_tag="VYP85_000457"
     CDS             26207..26410
                     /locus_tag="VYP85_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEV1881013.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            26492..27709
                     /locus_tag="VYP85_000458"
     CDS             26492..27709
                     /locus_tag="VYP85_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1881014.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            27971..28939
                     /locus_tag="VYP85_000459"
     CDS             27971..28939
                     /locus_tag="VYP85_000459"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1881015.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(29073..29354)
                     /locus_tag="VYP85_000460"
                     /pseudo
     CDS             complement(29073..29354)
                     /locus_tag="VYP85_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(29480..29713)
                     /locus_tag="VYP85_000461"
     CDS             complement(29480..29713)
                     /locus_tag="VYP85_000461"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881016.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(29706..29822)
                     /locus_tag="VYP85_000462"
     CDS             complement(29706..29822)
                     /locus_tag="VYP85_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1881017.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(30037..30387)
                     /locus_tag="VYP85_000463"
     CDS             complement(30037..30387)
                     /locus_tag="VYP85_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1881018.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            30643..33276
                     /gene="polA"
                     /locus_tag="VYP85_000464"
     CDS             30643..33276
                     /gene="polA"
                     /locus_tag="VYP85_000464"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1881019.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIALIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            33361..33798
                     /locus_tag="VYP85_000465"
     CDS             33361..33798
                     /locus_tag="VYP85_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1881020.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(33981..34991)
                     /locus_tag="VYP85_000466"
     CDS             complement(33981..34991)
                     /locus_tag="VYP85_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1881021.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            35140..36309
                     /locus_tag="VYP85_000467"
     CDS             35140..36309
                     /locus_tag="VYP85_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1881022.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            36306..37076
                     /gene="recO"
                     /locus_tag="VYP85_000468"
     CDS             36306..37076
                     /gene="recO"
                     /locus_tag="VYP85_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1881023.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            37073..38065
                     /gene="plsX"
                     /locus_tag="VYP85_000469"
     CDS             37073..38065
                     /gene="plsX"
                     /locus_tag="VYP85_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1881024.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            38071..38304
                     /locus_tag="VYP85_000470"
     CDS             38071..38304
                     /locus_tag="VYP85_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1881025.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            38350..38641
                     /locus_tag="VYP85_000471"
                     /pseudo
     CDS             38350..38641
                     /locus_tag="VYP85_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            38844..39074
                     /gene="blpU"
                     /locus_tag="VYP85_000472"
                     /pseudo
     CDS             38844..39074
                     /gene="blpU"
                     /locus_tag="VYP85_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            39789..41942
                     /locus_tag="VYP85_000473"
     CDS             39789..41942
                     /locus_tag="VYP85_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1881026.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            41955..43304
                     /locus_tag="VYP85_000474"
     CDS             41955..43304
                     /locus_tag="VYP85_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1881027.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            43474..44181
                     /locus_tag="VYP85_000475"
     CDS             43474..44181
                     /locus_tag="VYP85_000475"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1881028.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            44238..47963
                     /locus_tag="VYP85_000476"
     CDS             44238..47963
                     /locus_tag="VYP85_000476"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1881029.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVAIVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEVANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            48056..49498
                     /locus_tag="VYP85_000477"
     CDS             48056..49498
                     /locus_tag="VYP85_000477"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1881030.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGKLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEDRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            49535..50557
                     /locus_tag="VYP85_000478"
     CDS             49535..50557
                     /locus_tag="VYP85_000478"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1881031.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            50554..51099
                     /gene="purN"
                     /locus_tag="VYP85_000479"
     CDS             50554..51099
                     /gene="purN"
                     /locus_tag="VYP85_000479"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1881032.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            51183..51692
                     /locus_tag="VYP85_000480"
     CDS             51183..51692
                     /locus_tag="VYP85_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1881033.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            51717..53264
                     /gene="purH"
                     /locus_tag="VYP85_000481"
     CDS             51717..53264
                     /gene="purH"
                     /locus_tag="VYP85_000481"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1881034.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQKASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            53386..54648
                     /gene="purD"
                     /locus_tag="VYP85_000482"
     CDS             53386..54648
                     /gene="purD"
                     /locus_tag="VYP85_000482"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1881035.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            55051..55539
                     /gene="purE"
                     /locus_tag="VYP85_000483"
     CDS             55051..55539
                     /gene="purE"
                     /locus_tag="VYP85_000483"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1881036.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            55526..56617
                     /gene="purK"
                     /locus_tag="VYP85_000484"
     CDS             55526..56617
                     /gene="purK"
                     /locus_tag="VYP85_000484"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1881037.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            56627..56854
                     /locus_tag="VYP85_000485"
     CDS             56627..56854
                     /locus_tag="VYP85_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1881038.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVKAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            56917..58215
                     /gene="purB"
                     /locus_tag="VYP85_000486"
     CDS             56917..58215
                     /gene="purB"
                     /locus_tag="VYP85_000486"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1881039.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(58270..62208)
                     /gene="strH"
                     /locus_tag="VYP85_000487"
     CDS             complement(58270..62208)
                     /gene="strH"
                     /locus_tag="VYP85_000487"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1881040.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(62523..63239)
                     /locus_tag="VYP85_000488"
     CDS             complement(62523..63239)
                     /locus_tag="VYP85_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1881041.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
BASE COUNT        18688 a        11625 c        14480 g        18570 t
ORIGIN      
        1 tgagcaataa agctcatctc catctcccga ttgaaacagt cactccccgg actgtttcaa
       61 cgtcctagga cataatctca ggaagacgcg aaaaatcatg ctcaaagtga aaatcattga
      121 tcttgcgaat gacagttgaa gttgaaatag acaactgatg atcaatgtcg gtcatagaag
      181 tctttttaat tagcttctga gcaatctttt ggttgatgat acaaggaatt tgatgattct
      241 tcttgacgat agaagtttca gcgaccctca tttttgaaca gtgatagcac ttaaaacggc
      301 cttttctaag aagaattcta gtttgaattt tttatactag aaaatcagaa ccataatacc
      361 tatataaaaa tattatagtt ctaataggat ttacccaaaa gttttaaggc ggtcttttta
      421 gaactttaat cgtttgaaat ttaggtagca aatttgtttc tattctgtca acttttccta
      481 tttttatctt gttgagcctg gtattttaac aattcaggaa ttgatagtga atgtgtaaaa
      541 ttttttgtta gaataagttt ataaaaaaga aaaggagtat ttgattatgt tacaaaaaat
      601 ttatgagcag atggctaatt tctatgatag tattgaagaa gagtatggtc ctacatttgg
      661 tgataatttt gactgggaac atgttcattt taaattttta atttattatt tagtgagata
      721 tggcattggt tgtcgtaggg attttatcgt ttaccattat cgtgttgctt atcgtttgta
      781 tcttgaaaaa ttggtaatga atcggggttt tatttcttgt tgaggtaatt ttagtaaatt
      841 tccgaactaa tttactcttt tatggaaaga tgatagtaaa tagctagtaa tttttctaaa
      901 tcatttttta atagttggaa atagcaaatc tttctattgt ttcttcttga taaaaaggcg
      961 attttttatt ataataaatt gtaagatata attgcaggtg agagtcctgc catgtatgtg
     1021 agaaaggaag agcctgaggg ctcagacaag attatgactt cagttgttgt tgtaggtacc
     1081 caatggggtg atgaaggtaa agggaagatt acagacttcc tttcagcgaa tgcagaagtg
     1141 attgcacgtt accaaggtgg tgataatgct ggtcacacga ttgtgattga cggtaagaaa
     1201 tttaagttgc acttgattcc atctgggatt ttcttccctg aaaaaatatc tgtcattggg
     1261 aatggtatgg ttgtaaatcc taaatctctt gtaaaagagt tgagctatct tcatgaggaa
     1321 ggtgtaacaa ctgataactt gcgtatttct gatcgtgcgc atgttatttt gccttatcat
     1381 atcgagttgg atcgcttgca agaagaagct aagggcgaca ataagattgg tacgacaatt
     1441 aagggaattg gtccagctta tatggacaag gctgctcgtg ttggaattcg tattgcagat
     1501 cttttagata aagatatttt ccgtgagcgt ttagaacgta accttgctga aaagaatcgt
     1561 ctttttgaaa aattgtatga cagtaaagcg attgttttcg atgatatttt tgaagaatat
     1621 tacgaatatg gtcaacaaat caagaaatac gtgatagata catctgttat cttgaatgat
     1681 gcgcttgata atggcaaacg tgtgcttttt gaaggtgcac aaggtgttat gctagatatc
     1741 gaccaaggta cttatccatt tgttacgtca tcaaaccctg tagctggtgg tgtgacaatt
     1801 ggttctggtg tcggtccaag caagattgac aaggttgtag gtgtatgtaa agcttatacg
     1861 agtcgtgtag gagatggtcc tttcccaact gagttgtttg atgaagtggg agaacgtatc
     1921 cgtgaagtgg gtcatgagta tggtacaaca actggtcgtc cacgtcgtgt aggttggttt
     1981 gactcagttg tgatgcgtca tagccgtcgt gtttctggta ttactaacct ttctttgaac
     2041 tctattgatg ttttgagcgg tttggatact gtgaaaatct gtgtggccta tgatcttgac
     2101 ggtcaacgta ttgactacta tccagctagt cttgagcaat tgaaacgttg caagcctatc
     2161 tatgaagagt tgccaggttg gtcagaagat attaccggag ttcgcaattt ggaagatctt
     2221 cctgagaatg cgcgtaacta tgttcgtcgt gtgagtgaat tggttggcgt tcgtatttct
     2281 actttctcag taggtcctgg tcgtgaacaa acaaatattt tagaaagtgt ttggtcctaa
     2341 gagattttta agatttgttt aagataggtc gggtatacta tagacggtta caagaagacc
     2401 tcctaacttg ttgtaacaaa tatcctaaac ttttcttttt cataataatc tccctataga
     2461 gtcaccgcat tcggtggctt tttttgtgtt gggattcatg atataataat aaaatcgata
     2521 agtaggaaaa gagaaaagag atgtattata cgcttgaaga aaaagaagtc tttatgaggg
     2581 aggctttgag agaggctgag attgctcttg aacacgatga aattccaatt ggttgtgtga
     2641 ttgtcaaaga tggggaaatc attggtcgtg ggcataatgc gcgtgaggaa ttacagcgag
     2701 cggttatgca tgcggaaatt atggctatag aggatgcgaa cttgagtgag gagagctggc
     2761 gcttgctgga ttgcacactt tttgtgacca ttgaaccttg tgtcatgtgt agtggagcga
     2821 ttgggcttgc ccgcattcca aatgtggtct atggggctaa aaaccagaaa tttggcgctg
     2881 ctgggagttt gtacaatatc ttgacagatg agcgtctcaa tcatcgtgtg gaggttgaaa
     2941 taggaatttt ggaagatgaa tgcgcagcta tcatgcagga tttttttaga aatagacgga
     3001 aaaaataatt ttgcttttaa aatgaatagg aatgtgatat aataaatagt ggagcaacag
     3061 ttctgcgtga agcgggtcag gggaggaatc cagcagccct aagcgatttg aattgtgtgc
     3121 tcttttttcg tgctttttcc gaataaataa gatagaataa tctagaataa atgataatag
     3181 aaaagagaaa attatgaaaa ttcgtggttt tgaattggtt tcaagtttta cagatgaaaa
     3241 tttattgccc aagcgtgaga cagcgcatgc ggctggttac gacttaaagg ttgctgtgcg
     3301 tacagttgtt gcgccaggag agattgtctt ggttccgaca ggggttaagg cttatatgca
     3361 gccgactgag gttctctacc tctatgatcg ttcttcaaat cctcgtaaga agggcttggt
     3421 tttaattaac tcagttgggg tcattgatgg ggattattat ggaaatcctg gaaatgaagg
     3481 gcatattttt gcgcagatga agaatatcac agaccaagag gttgttcttg aagttgggga
     3541 acgtattgtc caggctgttt ttgctacttt cttaattgca gatggagatg cagctggtgg
     3601 cgttcgaact ggtggatttg gatcgacagg gcactagaat gaagattatc tttgtacgtc
     3661 atggggagcc agattaccgt gagttagagg agcgttctta tataggattt gggatagatt
     3721 tggcaccctt gtctgagatg ggacggcagc aagtccagaa attgagcaaa aatcctttac
     3781 tctcgtcagc tgaaataatc gtatcttctg cagtcacaag agctttagaa acggcttcgt
     3841 atgtggtctg tgctacgggt cttcctttaa gagtagagcc tttattacat gaatggcagg
     3901 tctataaaac aggaatagaa aactttgaaa cagctagaag actgttttta gaaaacaagg
     3961 gggagttgct tcctaatagt cctattcaat atgagacagc tacggaaatg aagtctcggt
     4021 ttctagaatg tatgtctaag tatcgagaac atcagactgt ggtagttgtt gctcatcgaa
     4081 tgctcatgcg ccagtttgtg ccaaatgaga agattgattt ttgccaagtg attgagtgtg
     4141 agttagagat ataggaagag gtttgtcatc gcaaagaaaa aagcgacatt tgtatgtcaa
     4201 aattgtgggt ataattcccc taaatatctg ggacgttgcc ccaactgtgg atcttggtct
     4261 tcttttgtgg aagaggttga ggttgccgag gtcaagaatg cgcgtgtgtc cttgacaggt
     4321 gagaaaacca agcccatgaa actagctgag gtgacttcca tcaatgtcaa tcgaaccaag
     4381 acggagatgg aggaattcaa ccgtgtgctt ggaggcggag tggtaccagg aagtctcgtc
     4441 ctcatcggtg gggatcctgg gattgggaaa tcaactcttc tccaacaagt ctcaacccag
     4501 ttgtcccaag tggggacagt tctctatgtc agtggggagg agtctgccca gcagattaaa
     4561 ctacgtgcag agcgcttagg tgatattgat agtgagtttt atctctatgc agagaccaat
     4621 atgcagagtg ttcgtgcaga agtggagcgt atccagccag actttcttat tattgattcc
     4681 atccagacca tcatgtctcc tgagatttca ggggtgcagg ggtctgtttc tcaggtacgt
     4741 gaagtgaccg ctgaactcat gcagttggcc aagaccaata acattgccat ctttatcgta
     4801 ggtcatgtga ccaaagaagg aaccttggct gggcctcgta tgttggagca tatggtggat
     4861 acggtgcttt actttgaagg ggagcgtcac cacacctttc gtattttgag agcggtcaaa
     4921 aatcgttttg gttccactaa tgagattggg atttttgaga tgcagtcggg cggcttggtt
     4981 gaggtactca atccgagtca agttttccta gaagagcgtt tggatggggc gactggttcc
     5041 tccatcgttg taaccatgga agggacgcgt ccgattttgg cggaggttca ggctttagta
     5101 acaccgacca tgtttggaaa tgccaagcgt actacgacag gacttgattt taaccgtgct
     5161 agcttgatta tggctgtttt ggaaaaacgg gcagggcttc tcttgcaaaa tcaggatgcc
     5221 tatctcaaat ctgctggtgg tgttaaattg gatgaacctg ccattgactt ggctgttgca
     5281 gttgctattg cttcgagcta caaagacaaa ccaactaatc ctcaggaatg ttttgtcgga
     5341 gaactgggct tgacaggaga gattcggcgc gtgaatcgta ttgagcaacg catcaacgaa
     5401 gctgctaaac tgggctttac taagatttat gtacctaaga attccttgac aggaatcact
     5461 ctgcctaagg aaattcaggt cattggcgtg acaacgattc aggaagtttt gaaaaaggtc
     5521 tttgcataat ccgtgacaaa ttctcttaaa aatgataaga taggagaaat atttgactat
     5581 caaattttca aggagggaat cgtgtcgtat tttgaacagt ttatgcaagc caatcaggct
     5641 tatgttgccc tacatgggca gttaaatctg ccacttaaac ccaaaacaag agtagctatt
     5701 gtgacctgta tggactctcg tctgcacgtt gcgcaagctc tgggcttggc acttggggat
     5761 gctcatatct tgcggaatgc aggtggtcga gtgactgaag acatgattcg ttcgctagtt
     5821 atttcccagc aacaaatggg gacaagagag attgtggtat tgcaccatac agactgtggt
     5881 gctcagacct ttgaaaatga accttttcag gagtatttaa aagaggaatt aggtgtagat
     5941 gtgtcagacc aggacttctt gcccttccaa gatatagaag agagtgtacg cgaggatatg
     6001 caactgctta tcgagtctcc cctaatacca gacgatgtca ttatctctgg tgctatttac
     6061 aatgttgata caggaagtat gacagtcgta gaattataaa tacttcattt agaaagaaag
     6121 tgtatgaaga aaagcagtat tttatttatt tttattttat tgctatgtat tggtttacag
     6181 tatgaaacca tctactatac ggacggttcg aggtcaggtg cggaatatgg actaatggga
     6241 atttctatct ttctagctct cttttacatg attccggctc tttattttct cttccgtatt
     6301 gggaaaaatg ggaattgcca aagaaggttt tgattctgtc tttattggga gggatgttcc
     6361 tttcaggatg gttgtctagt tttgctaata cttatatcca tgatttactg ggggttcttt
     6421 tcccagatag tacattttta aatgcctttg aaagtgctat tgtggctcct ttggtagaag
     6481 aacccttgaa attattgcca cttgtttttg ttttggcttt gattcctgtg cgaaaattaa
     6541 aatctttgtt tttacttgga attgcttccg gtttgggatt ccaaatgatt gaggatattg
     6601 gttatattcg tacggatttg ccagagggct ttgactttac tatttcgcga attttagagc
     6661 gtatcatctc aggaattgcc tctcactgga ctttttcagg tctagctgta gtaggtgttt
     6721 acttgcttta cagagcctat aaaggacaga aggttggcaa gaaacaggga cttatttttc
     6781 taggtttagc cttgggaact cacttcttgt ttaactctcc ttttgtggag ttggaaacag
     6841 agttgccttt agcgattcca gtggttacgg ctattgctct ctatggtttt tatcatgctt
     6901 attgctttgt tgagaaacac aatgagttga tgacctagaa tatttttcaa aagaatgatg
     6961 caagggtaca aatatggtgc ccttctttta tttttgttta ataaaaatag cataaaaatc
     7021 tagttatccg cataaaaact ggacttatca cactttatca aggtcaaaac cactcaattt
     7081 actactaatt tactacttat gaatgagctt tgatacgacg atttatcctt gaaaagtgaa
     7141 gatataaaga tacttccaat aaaatttgaa tatttaatag gtagacactt caaaaaatga
     7201 ggtgtctatt tttttacccg attttgaaag gaagtgaact tatgaaaaca aaaaatcaag
     7261 aatcaaaagg tcgttcccca ctctttaaga ccatcaaaca ttcattcagc caataaaaaa
     7321 gaaaggatag gtaaaaatat ggaacttaaa tttgtgattc ccaacatgga aaaaacattc
     7381 ggcaatttag aatttgctgg cgaggataaa gtcgttcagc gaagaatcaa cggacggcta
     7441 actgtcttat caagaagcta taatctctat tctgatgttc aaagagcaga tgatattgtg
     7501 gtggtgcttc ctgctgaagc tggcgaaaaa catttcggct ttgaggaacg tgtgaagtta
     7561 gtcaatccac gtattaccgc agagggctac aaaatcggca ctcgtggttt tacaaattac
     7621 cttttacatg ctgacgacat gataaaagaa taaagaaaga gaggaaaaat gatgagatta
     7681 gcaaatggca ttgtattaga taaagacacg acttttggag aattgaaatt ctctgctcta
     7741 cgtcgtgaag tgagaatcca aaatgaagac gggtcggttt cagatgaaat caaggaacgt
     7801 acctatgact taaaatccaa aggacaagga cgcatgattc aagtaagtat tcctgccagc
     7861 gtgcctttga aagagtttga ttataacgca cgggtggaac ttatcaatcc cattgcggac
     7921 accgttgcta ctgccaccta tcaaggagca gatgttgact ggtatatcaa ggcagacgat
     7981 attgtgctga caaaggattc tagttcattc aaagctcaac cacaagcaaa gaaagaaccg
     8041 acacaagaca aatagtcgct aggtagaaag gagacttttt cgcatgaaac agcgtggtaa
     8101 aaggattcgc ccatctggta aagatttagt ctttcatttt acgatagcgt cactcctgcc
     8161 tgttttcctg ctggttgtcg gactgtttca tgtgaagaca atccagcaga tcaactggca
     8221 ggattttaac ctatcacaag cagataagat tgacattccc tatttaatta tcagtttcag
     8281 tgtcgcaatt cttatctgct tgctggtagc gtttgtattc aaacgggttc gctatgatac
     8341 ggttaaacaa ctttaccacc gtcaaaaact ggcaaagatg atacttgaaa acaagtggta
     8401 tgaatctgaa caggtcaaaa cagagggttt ctttaaagat agtgctggtc gtacaaagga
     8461 aaagataacc tacttcccta aaatgtatta tcgacttaaa aatggcttga tacagatacg
     8521 ggtggaaatc acgctgggaa aatatcaaga ccaactctta cacttggaaa agaaattaga
     8581 gagtggcttg tactgtgagc tgacggataa agagttaaag gattcctatg tggaatatac
     8641 tttgctctat gacaccatag ccagtcgtat ttctattgat gaagtagaag ctaaagatgg
     8701 taaacttcgc ttaatgaaaa acgtatggtg ggaatatgat aagctccctc atatgttgat
     8761 tgctggtggt acaggtggcg gtaaaactta ctttatactg acactgattg aagccttgct
     8821 tcatacagat tcaaaactgt atattcttga cccgaaaaat gctgatcttg cggacttagg
     8881 ttctgtgatg gcaaatgtct actatagaaa agaagacttg ctttcttgca ttgaaacatt
     8941 ctatgaagaa atgatgaaac gtagtgagga aatgaagcag atgaagaact ataagactgg
     9001 caaaaattat gcttacttag gtctcccggc acacttctta atctttgatg aatacgtcgc
     9061 tttcatggaa atgctgggaa caaaagaaaa caccgcagtt atgaataagc tgaaacagat
     9121 tgtcatgtta ggtcgtcaag ctggcttctt tctaatactg gcttgtcaac gtccagacgc
     9181 aaaatattta ggcgacggaa tccgtgatca gtttaatttc agagtggctt taggtcgtat
     9241 gtctgaaatg ggctatggca tgatgtttgg cagtgacgta caaaaggatt tcttcttaaa
     9301 gcgaatcaaa ggtcgtggct atgttgatgt aggaacaagt gtcatatcag agttttatac
     9361 tccccttgta ccaaaaggat atgatttctt ggaggaaatt aaaaagttat ccaacagcag
     9421 acagtccacg caggcgacgt gcgaagcgga agtcgcaggt gtggactgat cttgctggct
     9481 ggtgtggcaa tagccacgcc agcacttaac cccccgtatc taacaggggg gtacaaatcg
     9541 acaggaaaca gtcaaaaaaa cattagaaaa tcctttggtt acaagggatt tacaaaattt
     9601 cagcgtatgt caaatgggct ttaaaagttg acatacgcct ttttgattgg agggattttt
     9661 actgaatgaa caaacttggt tacagcattt aaaagaaaaa cgcttggctt atggactatc
     9721 tcaaaaccgt ttagctgttg cgactggtat tacaaggcag tatctaagcg atattgaaac
     9781 aggaaaagtc aagccatcag aggatttaca gcagtccctt tgggaagctc tggaacgctt
     9841 caatcccgac gctccccttg aaatgctgtt tgattatgta agaattcgct ttccgacaac
     9901 agacgtacag caggtggtcg aaaacatctt acaactgaaa ctgtcctatt ttcttcatga
     9961 ggactatggt ttctattctt attcagagca ttatgcttta ggcgacatat tcgtcctttg
    10021 ctcccatgaa ctggacaaag gagttctggt ggaattgaaa ggtcgtgggt gcagacaatt
    10081 tgaaagctat cttctggcac aacaaagaag ctggtatgag ttctttatgg acgttttggt
    10141 ggctggcggt gtgatgaaac gccttgacct tgccattaac gataagacag ggattttaaa
    10201 tatccctgta ctcactgaaa agtgccaaca ggaagaatgt atctccgtct tccgcagttt
    10261 taaaagctat cgcagtggcg aactggtacg caaagaggaa aaggaatgta tgggaaacac
    10321 cctctatatc ggttcattac aaagtgaagt ttatttctgt atctatgaaa aggactacga
    10381 gcagtacaag aaaaatgata ttcccattga agacgcagaa gtaaaaaacc gttttgagat
    10441 tcgattgaaa aatgagcgtg cctattatgc agtccgtgat ttactcgtct atgacaatcc
    10501 agagcatacc gcctttaaaa ttatcaatcg gtatatccgt tttgtagata aagacgattc
    10561 caaacctcgt tctgattgga aactgaatga agaatgggct tggtttattg ggaacaatcg
    10621 tgaacgatta aaactaacca caaaaccaga gccttactcc ttccaaagga cgctgaactg
    10681 gctatctcat caagttgccc cgaccttaaa ggttgcgatt aaacttgatg aaatcaacca
    10741 gacgcaggtt gtaaaagaca ttctcgacca tgcgaaactg acagaccgac acaagcagat
    10801 tttgaagcaa cagtcagtaa aagaacagga cgtgataaca acaaaaaaag gatatctgtc
    10861 aaccatacca gttgacagat atccaaaaaa agatataatg ggagataaga cggttcgtgt
    10921 tcgtgctgac ttgcaccata tcataaaaat cgaaacagca aagaatggcg gaaacgtaaa
    10981 agaagttatg gaaataagac ttagaagcaa acttaagagt gtgttgatag tgcattatct
    11041 taaaattttg tataatagga attgaagtta aattagatgc taaaaatttg taattaagaa
    11101 ggagggattc gtcatgttgg tattccaaat gcgtaatgta gataaaacat ctactgtttt
    11161 gaaacagact aaaaacagtg attacgcaga taaataaata cgttagatta attcctacca
    11221 gtgactaatc ttatgacttt ttaaacagat aactaaaatt acaaacaaat cgtttaactt
    11281 ctgtatttgt ttatagatgt aatcacttca ggagagatta catgaacaaa aatataaaat
    11341 attctcaaaa ctttttaacg agtgaaaaag tactcaacca aataataaaa caattgaatt
    11401 taaaagaaac cgataccgtt tacgaaattg gaacaggtaa agggcattta acgacgaaac
    11461 tggctaaaat aagtaaacag gtaacgtcta ttgaattaga cagtcatcta ttcaacttat
    11521 cgtcagaaaa attaaaactg aatactcgtg tcactttaat tcaccaagat attctacagt
    11581 ttcaattccc taacaaacag aggtataaaa ttgttgggaa tattccttac catttaagca
    11641 cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc tgacatctat ctgattgttg
    11701 aagaaggatt ctacaagcgt accttggata ttcaccgaac actagggttg ctcttgcaca
    11761 ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga atgctttcat cctaaaccaa
    11821 aagtaaacag tgtcttaata aaacttaccc gccataccac agatgttcca gataaatatt
    11881 ggaagctata tacgtacttt gtttcaaaat gggtcaatcg agaatatcgt caactgttta
    11941 ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt aaacaattta agtaccatta
    12001 cttatgagca agtattgtct atttttaata gttatctatt atttaacggg aggaaataat
    12061 tctatgagtc gcttttttaa atttggaaag ttacacgtta ctaaagggaa tggagataaa
    12121 ttattagata tactactgac agcttccaag aagctaaaga ggtccctagc gcctacgggg
    12181 aatttgtatc gataaggggt acaaattccc actaagcgct cgggacccct tgtaggaaaa
    12241 tgtcctaagt gggatatctg tcaactggta tggttgacta aaaatacttc ctacgaaaat
    12301 gtagggggta tttttttacg aaaaaataca atcgattctt aaaaagaaaa atttttgatt
    12361 ggcaaaacca taacaagttc gttttagggt tttgattttg cgattgatgc cttctaaagg
    12421 accattagag tattcaaatt tagcgctatt taagacatat tttctgtttt gacgaagggt
    12481 ttgaatagca gtatccattt ctgtattggt tttttggtag tctaagatgg ttgactctag
    12541 taattcacta ttgcgctcgt ttagggcttt cgtgatatct tggtaagttt ggtatacttc
    12601 agcgaacttg gaaaatttac tagtaatgag atcaacagca ttttggcgag tcatatattg
    12661 tttaacgccg cgaagaaaaa ctacttcttc agggtgaaga tcttcagctt ttttatggaa
    12721 tagcttccaa tgtgacttca taattttata ttcttggctc tgtttatcaa gttgctttag
    12781 gatagagata cgacaattgt ccaaagcgcg accagctaat tgtacaaggt ggaagcgatc
    12841 aataatgata ttggcattag ggaaaaggcg atagataaaa ctttgatatt gagcatttaa
    12901 atcaattaca actgattgaa cgcattcgcg ttcggctttt gaataacgac tttcaaaata
    12961 atcaacaatg gtaggtgata gacgatcctg taactttgtg acaatttggt gggtttcagc
    13021 gtcacaacag ataaaggaca tcacagactt aattgaacga aactcgtcaa aacatagatg
    13081 cttaggcaac ttagccacac gatagtgtgg ttccatgcgc tctaagattg ttcgacgaac
    13141 actgctagga gagcagtgac acatttcagc aataagctga ccagataagc ctttacgagc
    13201 taaaagcatg atttgatttt tgagatcact ggataaggtt tgattttctt tggttaaatt
    13261 agtaatagca ccaaaagtag tatggcatga tttacattta tagcgttgtt tacgaagctc
    13321 tagttcatat cttctcccat ttaaacttgc cagtcgtaca tgagttttgc gaaagccatc
    13381 cttattaact gtgggaaagc cacagttacg acaacgatta atcggataag aaagagtagc
    13441 tgttattagc gttatatact ctttaacaga atcgttgttg tgttcagctt cttcaacaga
    13501 aataatttta atatttttat ctttaattcc aagaatattt aggatagaat cattatggga
    13561 catttgttta accttctttc atgatttttg tggtgaattg attgtataac gaggggacag
    13621 caaatgtcct cttttttgta taaaaaaatc tggcatggaa tctctatcca taccagaaag
    13681 tgtatacccc aaaaaaataa ctcaaataca aattcattga atatagagag gagaacattt
    13741 ttatgaattt tggacaaaac ctttataact ggtttctatc aaacgctcaa tcactggtgc
    13801 ttttagcaat cgttgtgatt ggcttgtatc ttggcttcaa gcgtgagttt agcaaactga
    13861 ttggcttttt aattattgcg attattgcgg ttggcttagt cttcaacgct gctggagtaa
    13921 aagacatttt actagagcta ttcaatcgca ttattggtgc ttaaataaaa ccgttctttt
    13981 gtggaatata agtggttttc ttatgttccg caaaggaatg gtacaccaaa cgaagtgcgg
    14041 tagggatttt tgaatctcta caaagaaagg acgtgaatat atggacgata tgcaagtcta
    14101 tattgcgaat ttaggcaaat acaatgaggg cgaattggtc ggtgcgtggt ttacctttcc
    14161 cattgacttt gaggaagtca aagagaaaat cggcttgaat gatgaatatg aggaatacgc
    14221 cattcatgac tacgagttac cctttacggt tgacgaatac acttccattg gcgaactcaa
    14281 tcgactatgg gaaatggtat cggaattacc cgaagaatta caatcggagc tatctgctct
    14341 gctcactcat ttttcaagca ttgaagaact aagcgaacat caagaggata ttatcattca
    14401 ttccgattgt gatgatatgt atgacgtggc acgctactac attgaagaaa cgggtgcttt
    14461 aggcgaagta ccagctagtc ttcaaaacta tattgattat caagcctatg gtcgggattt
    14521 agacctttca ggaacgttta tctcaaccaa tcatgggatt tttgaaatcg tctattaaat
    14581 ctgtcggtac attactactg gcagattttc tattttacgg ggtggctcaa tcagctaccc
    14641 ctatttttta tgaaaggatt gattacatga agaaaatacg aagctatacc agtatctggt
    14701 ctgtggaaaa ggtactgtat tctatcaatg attttagact tccgtttccc ataaccttta
    14761 cgcaaatgac atggtttgtc gtgtcactct ttgcagtgat gatacttggc aacttgcccc
    14821 ctctttccat gatagaggga gcatttctca aatactttgg gattcctgtg gctttcacat
    14881 ggtttatgtc tacaaaaact tttgatggta aaaagcctta tggatttttg aagtctgtca
    14941 ttgcttatgc actgcgacca aagctgacct atgcaggaaa aaaagtaacg cttggcagaa
    15001 accagccaca agaagccatt acagcagtta ggagtgaatt ttatggcata tccaattaaa
    15061 tacattgaaa acaatctcgt ctggaataaa gacggggaat gttatgctta ctatgagctt
    15121 gttccttaca attactcatt tctaagtcca gaacagaaaa tacaagtgca tgattctttc
    15181 agacagctta tcgcacaaaa tcgtgatggc aaaattcatg ctttacaaat cagtacagaa
    15241 tccagcatac gttctgcaca agagcgttcc aaaaatgaag tcactggcaa gctcaaagcg
    15301 gttgcctatg acaaaatcga ccaacagaca gacgctttaa tatccatgat tggcgaaaat
    15361 caagtgaact accgtttctt tatcggcttt aagttgcttc tcaacgatca ggagttttct
    15421 atgaaaagtc ttaccgttga agcaaaaaat gctttgtctg attttgtcta tgatgtgaac
    15481 cataagctga tgggcgattt tgttagtatg agtaatgatg aaatcctgcg ttttcagaag
    15541 atggaaaagc tcttagaaaa taaaatctct cgtcgtttca aaatccgcag gttagataag
    15601 gacgacttcg gctatctgat tgaacacctt tacggacaga caggcactgc ctatgaagag
    15661 tatgagtacc atctatcaaa gaaaaagctg gataatgaaa cgctgattaa atactatgac
    15721 ttgattaagc ctactcgctg tttggtggaa gaaaaacagc gatatttgaa aatccagcag
    15781 gaagatgaaa ccgtctatgt agcttacttt accattaaca gcattgtcgg agaactggac
    15841 ttcccgtcct ctgaaatctt ctactaccag caacagcaat ttacattccc gattgatacg
    15901 tcaatgaatg tggaaattgt agcgaatcgt aaagccctat ctactgtccg caataaaaag
    15961 aaagaactga aagacttgga taaccacgct tggcaaagtg ataatgaaac cagctccaat
    16021 gtggcggaag ctctggaaag tgtgaatgag ctggaaacca atttagacca aagcaaggaa
    16081 tctatgtaca agctgtctta tgtggtaagg gtatcagcaa atgatcttga cgaactcaaa
    16141 cgtcgttgta atgaagtgaa agatttttat gacgatttaa gcgtaaaact ggtacgacca
    16201 tttggggata tgctcggctt acatgaagaa tttttacctg ccagcaagcg ttatatgaat
    16261 gattatattc aatacgtgac ctctgatttc ctcgctggtt taggttttgg tgctactcaa
    16321 atgctggggg aaaatgaggg gatttatgtt ggctacagct tagatactgg acgcaatgtc
    16381 tatctgaaac ctgctcttgc cagtcaaggg gttaagggtt cagtaaccaa tgcgttagcg
    16441 tcggcttttg ttggttcgct gggtggtggt aaatcctttg cgaataacct tatcgtctat
    16501 tatgcggtgc tttatggggc acaagcagtg attgtagacc caaaagcaga acgtggcaga
    16561 tggaaagaaa ccttgccaga gatttcccat gaaatcaata tcgtcactct gacttctgat
    16621 gagaaaaaca aaggcttact tgacccttat gtgattatga aaaatcccaa agattctgaa
    16681 tcactggcta ttgatattct gacattcctt acggggattt cctctcgtga tggggaacgc
    16741 ttcccaatcc ttagaaaagc cattcgtgca gtaaccaata gtgaagtacg agggttgatg
    16801 aaagtgattg aggaattacg ggttgagaat acgccactaa gtaccagtat agccgaccat
    16861 atcgaaagtt ttacagacta tgactttgca catttattat tcagtaatgg ttatgtggag
    16921 cagtctatca gcttagaaaa acaactgaac attatacagg ttgcggactt ggtacttccc
    16981 gacaaggaaa cttcctttga ggaatatacc actatggagc ttttatccgt tgctatgctg
    17041 attgtcatta gtacctttgc tttagacttt atccatacag accgaagcat tttcaagatt
    17101 gtagatttag acgaagcatg gagcttttta caggtagcac aaggaaaaac actatctatg
    17161 aagctggttc gggctggtcg tgctatgaac gctggggtat atttcgtgac ccaaaataca
    17221 gacgacctct tagatgaaaa actgaaaaat aacctcggct taaaatttgc atttcgttcc
    17281 actgacctta acgagattaa aaagacctta gccttttttg gtgtagaccc agaggacgaa
    17341 aacaatcaga agcgattgcg tgatttggaa aacgggcaat gccttatcag tgatttatat
    17401 ggtcgtgtcg gtgtgataca gttccaccct gtatttgaag aactgctcca tgcctttgat
    17461 accagaccac ctgtgcgaaa agaggtgtaa atgtgaaacc atcaatagta aacagaataa
    17521 aatcaaactg gacgctgaaa cgtctaggta aagtggcaat gacagtggct ttcacacttg
    17581 tgattgccat ttttctttta gccatgctgg gaacggtggt tcaagctgcg ggcttggtag
    17641 atgatacggt caatgtggca aatgaataca gccgataccc acttgaaaac tatcaactgg
    17701 atttttatgt ggataatagc tggggctggc ttccgtggaa ctggtcggac gggattggaa
    17761 aacaggtcat gtatggacta tatgccatta ccaattttat ttggacaatc agtttgtatg
    17821 tttccaatgc gacaggttac ttagtacagg aagcctattc cttagacttc atttccgcta
    17881 cagcagattc cattggtaag aatatgcaga ccttagctgg tgtgagtgca aacggatttt
    17941 caacagaggg tttctatgtt ggattcctct tactcttgat tttggttctt ggggtttatg
    18001 ttgcctatac gggactgata aagagagaaa ccacaaaggc aattcatgcc attatgaatt
    18061 ttgtgctggt gtttatccta tcggcttcct ttattgccta cgctcccgac tacattaaaa
    18121 aaatcaatga cttttcatca gacatcagta atgccagttt atcacttggc acgaagattg
    18181 tcatgcccca ttccgatagt caaggcaagg acagcgtgga cttaatcaga gatagcctgt
    18241 tttccataca ggttcagcaa ccgtggctac tgcttcaata caacagttca gacattgaaa
    18301 gtatcggtat tgaccgtgtg gaaagcctgc tctccaccag cccagattcc aacaatggcg
    18361 aagacagaga aaaaattgtt gcggaagaaa ttgaagacag aagcaatacc aatctaacca
    18421 ttacaaagac cattaaccgt ttaggtacag tcttcttcct atttgtcttc aatattggga
    18481 tttccatatt tgtattccta ttaacaggaa tcatgatttt ctcgcaggta ctttttatca
    18541 tctatgctat gtttctgcct gtgagcttta ttttaagcat gattccatca tttgatggta
    18601 tgtcaaaacg agccataaca aagctcttta ataccatttt gacacgagct ggaatcacat
    18661 tgattattac gacagcattt agtatttcaa ccatgctcta taccttatcg gctggttatc
    18721 cgttcttttt gattgctttt ctacagattg tgacctttgc aggaatctac ttcaagctgg
    18781 gcgatttaat gagtatgttt tctctacaga gtaacgattc tcaaagtgtg ggaagtcgtg
    18841 tgatgagaaa acctcgtatg cttatgcacg ctcacatgca ccgtctacag cggaaacttg
    18901 gacgttccat gactactcta ggggctgggt ctgccattgt tacaggtaaa aaaggacagt
    18961 cgggttcggg gagttctgca aggacacaag cagatcactc ccgaccagac ggaaaggaaa
    19021 aatcaacact tggaaaacgt atcggtcaaa ccatcggtac agtagctgat accaaagaca
    19081 gaatggtaga cactgctagt ggtttgaaag aacaggttaa agatttgccg accaatgcaa
    19141 gatatgcagt atatcaagga aaatccaaag taaaagagaa tgtccgtgat ttaaccagta
    19201 gtatttctca aaccaaagcg gacagagcca gtggacgcaa ggaacagcag gaacaaaggc
    19261 gaaaaaccat tgcgaagcgt cgctctgaaa tggaacaggt caaacagaaa aaacagcctg
    19321 cttcttctgt tcatgaaaga ccgactacaa gacaagaaca atatcatgat gaacagacct
    19381 caaaacagtc taatattcag acttcatata aggaatctca acaagccaaa caagagcgtc
    19441 cagcagttaa gtccgatttt tcaagtccaa aagtggaacg ccaaggcaat accgttcaag
    19501 aaaaaaccgt tcaaaagcca gcaacttcaa ccactacagc agatagaact tcacaacgtc
    19561 caatcacaaa agaacgtccg tctactgttc aaagagtacc actacaaaat acaagaagta
    19621 gaccaccaat caaaaccgcc accattaaga aagtcggtaa gaaaccatga agttgaaaac
    19681 tttagtgatt ggtggttctg gattattctt gatggtcttc tcactgcttc tgtttgttgc
    19741 cattttattt tcagatgaac aggacagcgg aatttccaat attcattatg gaggtgtgaa
    19801 tgtttccgca gaagtgctgg ctcataagcc tatggtagaa aaatatgcca aagaatatgg
    19861 cgttgaagaa tatgtcaaca tacttcttgc gattatacag gtggaatcgg gcggtactgc
    19921 ggaagatgtt atgcagtcct cggaatccct cggtcttcca cctaattcat tgagtacaga
    19981 agaatccatt aagcaaggtg tgaagtattt cagtgaatta ttagccagta gcgaaaggct
    20041 cagtgtagat ttagaatcgg ttatccagtc ctacaattat ggtggtggtt tcttagggta
    20101 tgtggctaat cgtggaaata aatatacctt tgaactggct caaagtttct caaaagagta
    20161 ttcaggtggc gaaaaagtgt cttaccccaa tcccatagcc atacctatca atgggggctg
    20221 gcgatacaac tatggcaata tgttttatgt gcaactggta acgcagtatc ttgtcacaac
    20281 agagtttgat gatgatacgg tacaagccat catggacgaa gcactgaaat atgagggctg
    20341 gcgatacgtt tacggtggag cttccccgac tacttctttt gattgtagcg gactgacaca
    20401 atggacgtat ggaaaagctg gaattaactt accacgaacc gcacaacagc aatatgatgt
    20461 gacccagcat atcccactat cggaagcaca agctggcgat ttggttttct ttcattctac
    20521 ctataacgct ggctcttata ttactcatgt tgggatatac cttggcaata accgtatgtt
    20581 tcatgcaggc gacccaatcg gttatgccga cttaacaagc ccctactggc aacagcattt
    20641 agtgggagca ggacgaatca aacaatgaga aaggaagatt taatgatgaa atttagaaaa
    20701 aatcagaata aagaaaaaca gataccaaag gaaaagaaac ctcgtgtcta taaggtcaat
    20761 cctcataaaa aggttgtgat tgccttgtgg gtacttttag ggcttagttt cagctttgcg
    20821 atattcaagc actttacagc tatagatact catactattc acgaaacaac tatcatagaa
    20881 aaggaatacg ttgatactca tcatgtagaa aattttgtag agaactttgc gaaagtctac
    20941 tattcatggg agcaatccga taagtccatt gataatcgaa tggaaagtct aaaaggctat
    21001 ctgacagatg aacttcaagc tctcaatgtt gatacagtac gcaaagatat tcctgtatcg
    21061 tcttctgtaa gaggatttca gatatggacg gtagagccaa ctggcgacaa tgagtttaat
    21121 gtaacctaca gtgtagacca gctcattaca gagggagaaa atacaaagac cgtccactct
    21181 gcttatatag tgagtgtcta tgtagatggt tctggaaata tggtactggt taagaatccg
    21241 accattacca acatacctaa gaaatcaagt tataaaccaa aagccattga aagtgagggg
    21301 acggttgatt ccattacaac caatgaaatc aatgagtttt taacgacgtt cttcaagctc
    21361 tatcctacag cgacagccag tgaactttcc tactatgtga atgacgggat attaaaacca
    21421 atcggaaaag agtacatctt tcaagaactg gtaaatccta ttcacaatcg taaggataat
    21481 caagtcacgg tatcgctgac agtggagtat atcgaccagc agaccaaagc aacgcaggta
    21541 tctcaatttg atttggtact tgaaaagaac gggagtaatt ggaagattgt aaaataacaa
    21601 atattggtac atgattacag atactttgta atcatgtact ctttttgata aaaaattgga
    21661 gattccttta caaatatgct cttacgtgct attatttaag tgactattta aaaggagtta
    21721 ataaatatgc ggcaaggtat tcttaaataa actgtcaatt tgatagcggg aacaaataat
    21781 tagatgtcct tttttaggag ggcttagttt tttgtaccca gtttaagaat acctttatca
    21841 tgtgattcta aagtatccag agaatatctg tatgctttgt atacctatgg ttatgcataa
    21901 aaatcccagt gataaaagta tttatcactg ggatttttat gcccttttgg gtttttgaat
    21961 ggaggaaaat cacatgaaaa ttattaatat tggagtttta gctcatgttg atgcaggaaa
    22021 aactacctta acagaaagct tattatataa cagtggagcg attacagaat taggaagcgt
    22081 ggacaaaggt acaacgagga cggataatac gcttttagaa cgtcagagag gaattacaat
    22141 tcagacagga ataacctctt ttcagtggga aaatacgaag gtgaacatca tagacacgcc
    22201 aggacatatg gatttcttag cagaagtata tcgttcatta tcagttttag atggggcaat
    22261 tctactgatt tctgcaaaag atggcgtaca agcacaaact cgtatattat ttcatgcact
    22321 taggaaaatg gggattccca caatcttttt tatcaataag attgaccaaa atggaattga
    22381 tttatcaacg gtttatcagg atattaaaga gaaactttct gccgaaattg taatcaaaca
    22441 gaaggtagaa ctgtatccta atatgtgtgt gacgaacttt accgaatctg aacaatggga
    22501 tacggtaata gagggaaacg atgacctttt agagaaatat atgtccggta aatcattaga
    22561 agcattggaa ctcgaacaag aggaaagcat aagatttcat aattgttccc tgttccctgt
    22621 ttatcacgga agtgcaaaaa acaatatagg gattgataac cttatagaag tgattacgaa
    22681 taaattttat tcatcaacac atcgaggtcc gtctgaactt tgcggaaatg ttttcaaaat
    22741 tgaatataca aaaaaaagac aacgtcttgc atatatacgc ctttatagtg gagtactaca
    22801 tttacgagat tcggttagag tatcagaaaa agaaaaaata aaagttacag aaatgtatac
    22861 ttcaataaat ggtgaattat gtaagattga tagagcttat tctggagaaa ttgttatttt
    22921 gcaaaatgag tttttgaagt taaatagtgt tcttggagat acaaaactat tgccacagag
    22981 aaaaaagatt gaaaatccgc accctctact acaaacaact gttgaaccga gtaaacctga
    23041 acagagagaa atgttgcttg atgccctttt ggaaatctca gatagtgatc cgcttctacg
    23101 atattacgtg gattctacga cacatgaaat tatactttct ttcttaggga aagtacaaat
    23161 ggaagtgatt agtgcactgt tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc
    23221 tacagtcatt tatatggaga gaccgttaaa aaatgcagaa tataccattc acatcgaagt
    23281 gccgccaaat cctttctggg cttccattgg tttatctgta tcaccgcttc cgttgggaag
    23341 tggaatgcag tatgagagct cggtttctct tggatactta aatcaatcat ttcaaaatgc
    23401 agttatggaa gggatacgct atggttgcga acaaggatta tatggttgga atgtgacgga
    23461 ttgtaaaatc tgttttaagt atggcttata ctatagccct gttagtaccc cagcagattt
    23521 tcggatgctt gctcctattg tattggaaca agtcttaaaa aaagctggaa cagaattgtt
    23581 agagccatat cttagtttta aaatttatgc gccacaggaa tatctttcac gagcatacaa
    23641 cgatgctcct aaatattgtg cgaacatcgt agacactcaa ttgaaaaata atgaggtcat
    23701 tcttagtgga gaaatccctg ctcggtgtat tcaagaatat cgtagtgatt taactttctt
    23761 tacaaatgga cgtagtgttt gtttaacaga gttaaaaggg taccatgtta ctaccggtga
    23821 acctgtttgc cagccccgtc gtccaaatag tcggatagat aaagtacgat atatgttcaa
    23881 taaaataact tagtgtattt tatgttgtta tataaatatg gtttcttgtt aaataagatg
    23941 aaatattttt taataaagat ttgaattaaa gtgtaaagga ggagatagtt attataaact
    24001 acaagtggat attgtgtcct gtatgtggaa ataaaacacg attaaagata agggaagata
    24061 ctgaattaaa aaaattcccc ctctattgtc cgaaatgcag acaagaaaat ttaattgaaa
    24121 taaagcagtt caaagtaact gtgattacag agccagacgc aaagacgcag agccgataaa
    24181 atgagattaa tacaatctca ttttatcggc tctttccgtt atgtatggat tcttttaatt
    24241 agtcttcgat gtttcttgct tcgttgatac cgctggctaa agattccatt aaggatagtt
    24301 ctttgtctgt aaagctatcc atgtatttct ctatctgtaa tcgtcgggtg ctttttacca
    24361 agttattagc aggtaagaaa aattcatcaa cggaaacatg aagtaacgat acaaggtcat
    24421 aaagaacttg tatgctgggg tgttgccctt tattttcaat attagttaag taccgtgggt
    24481 caatttcaat caatgctccc acttgttcac gagttaaacc tcgtttcaat cgagcttctt
    24541 taatggctaa accaaaggct ctaaaatcat atttatcttc ttttttacgc atagtagacc
    24601 acctctatac attttattgt tcctactgaa ttaaaaacag gtatagaaaa acgtgttata
    24661 tggtttatag gtttatattt aataaaaagc actactaaac gccaataaaa aaaaccgtta
    24721 tatggtagtg ctatttacgc tgttaaaata ttgtatatta cttccaaatg gcggtttgtt
    24781 ggaggtcaac gtcgccatga agtacatcat atacaataaa tttccttaca ttgggttctt
    24841 gtcaaaaaaa gtcgtctatc tgcaatagat aagtacgtcc accaatgtgg ttttataaat
    24901 catatagata gaataacaga agcatgtaaa cagagaaata aatctgttta tatgcttttt
    24961 tggctattca gaactttttt acaaagttta tttatcagta atgcaacaaa tccccctttc
    25021 acattgggac taagagtgaa aggagataaa cgagcaaggc tcacttcctt tcctagacag
    25081 aaagggggtg agaaacatga aaccatcttc ttttcagacc acaatagaaa atcagtttga
    25141 ctatatctgt aaacgtgcta tggaagacga gcgaaagaat tatatgcttt atctttcaag
    25201 gattgcaaag cgtgaggtgt ccttttcgga tgttggcgat tatcttgtta gccagtttgc
    25261 gacaacagat aactattcaa ctgactttca gatttttaca ctcaatgggt tatcagtagg
    25321 cgttgaaaat gatttgttga gtgaagcatt acgtgagttg ccagacaaga aacgtgaaat
    25381 tctactgctg ttttacttta tggacatgag cgattcagaa attgcagacc tgttgaaatt
    25441 gaaccgttct actgtctatc ggcatagaac cagtggacta gccttaatta aaaagtttat
    25501 ggaggaattt gaagaatgaa aacacaatat cctatgattc cctttcctct cattgtaaag
    25561 gcaacagatg gcgataccga agcgattaac cagattctac atcattacag agggtacata
    25621 acgaagcgtt ccctacgact tatgaaagat gaatatggca atcaaagtat ggtcgttgat
    25681 gaagtcttac gtggaagaat ggaaaccaga ctgattacaa agattttgtc atttgaaatt
    25741 aagtaatatc ctctctcctt tcgtggaagc gtgctaaacc attccacgct tcccgaacag
    25801 ggaggtttgt tattccacca aagcatattg agctttcaat gtgttttgat aggctaacga
    25861 gccattgttc tttgaaaact gaataaaagt aatcgaatac gtttcgataa gaaaagagcc
    25921 aacggaacta accgccatga cctatcttat aaagatagcg agcgattcat gttagtgatc
    25981 cgagaagcaa tctttagcag gattgcctgc aacgacattc ttatcgtgat aatgatactc
    26041 ccatacagtc aatagtccga gcgtgataaa accgtcgcag gcaatgagta tggctacatg
    26101 agaaccatgc aggggtggaa ctcccgtgag ctttgctaaa gctgttcgat tgctggtaaa
    26161 acaactttta tgaaatccaa ataagtgatt tggaaaggag gattttatga agcagactga
    26221 cattcctatt tgggaacgtt ataccctaac cattgaagaa gcgtcaaaat attttcgtat
    26281 tggcgaaaac aagctacgac gcttggcaga ggaaaataaa aatgcaaatt ggctgattat
    26341 gaatggcaat cgtattcaga ttaaacgaaa acaatttgaa aaaattatag atacattgga
    26401 cgcaatctag cgtcgccaaa gggtcttgta tatgataaaa tagtattaag tcgtatcaag
    26461 gctctttcca taaaggaaag gagcaaatgc catgtcagaa aaaagacgtg acaataaagg
    26521 tcgaatctta aagactggag agagccaacg aaaagacgga agatacttat acaaatatat
    26581 agattcattt ggagaaccgc aatttgttta ctcgtggaaa cttgtggcta cagaccgagt
    26641 accagcagga aagcgtgatt gtatctcact tagagagaaa atcgcagagt tacagaaaga
    26701 cattcatgat ggtattgatg ttgtaggaaa gaaaatgaca ctctgccagc tttacgcaaa
    26761 acagaacgct caaagaccaa aggttagaaa aaacactgaa actggacgca aatatcttat
    26821 ggatattttg aagaaagaca agttaggtgt aagaagtatt gacagtatta agccatcaga
    26881 cgctaaagaa tgggctatta gaatgagtga aaatggttat gcttatcaaa ccatcaataa
    26941 ctacaaacgt tctttaaagg cttcattcta tattgctata caagatgatt gtgttcggaa
    27001 gaatccattt gactttcaac tgaaagcagt tcttgatgat gatactgtcc ctaagaccgt
    27061 actaacagaa gaacaggaag aaaaactgtt agcctttgca aaagctgata aaacctacag
    27121 caaaaattat gatgaaattc tgatactctt aaaaacaggt cttcgtattt cagagtttgg
    27181 tggtttgaca cttccagatt tagattttga gaatcgtctt gtcaatatag accatcagct
    27241 attgagagat actgaaattg ggtactacat tgaaacacca aagaccaaaa gtggcgaacg
    27301 tcaagttcct atggttgaag aagcctatca agcatttaag cgagtgttag cgaatcgaaa
    27361 gaatgataag cgtgttgaga ttgatggata tagtgatttc ctctttctta atagaaagaa
    27421 ctatccaaaa gtggcaagtg attacaacgg catgatgaaa ggtcttgtta agaaatacaa
    27481 taagtataac gaggataaat tgccacacat cactccacat agtttgcgac atacattctg
    27541 taccaactat gcaaatgcag gaatgaatcc aaaggcatta cagtacatta tgggacatgc
    27601 taatatagcc atgacgctga actattacgc acatgcaaca ttcgattctg caatggcaga
    27661 aatgaaacgc ttgaataaag agaagcaaca ggagcgtctt gttgcttagt agtacaaatg
    27721 aatttactac ttatttacca cttctgacag ctaagacatg aggaaatatg caaagaaacg
    27781 tgaagtatct tcctacagta aaaatactcg aaagcacata gaataaggct ttacgagcat
    27841 ttaagaaaat ataaaaagat aattagaaat ttatactttg tttgattgaa aaatagtgca
    27901 aaaagcgcta caatggtaga tggaaaatct tgtgaaaagc acaagttata catatatacc
    27961 ggaggaaatc atgtcttttt ctgatttaaa gctgtttgcc ctttcttcta ataaagaatt
    28021 ggcagaacgt gtggcgcagg agattgggat agagttgggg aaatcaagtg ttcgccaatt
    28081 ttcagatgga gagattcagg tcaacattga agaatcaatc cgtgggaaac acgtctttat
    28141 cttacaatca actagttcgc ctgtaaatga caatctgctt gaaattttga ttatggtaga
    28201 tgctttgaag cgtgcgagtg cagaatctgt taatgttgtc atgccttact atgggtatgc
    28261 acgtcaggat agaaaggcga gagcgcgtga gccaatcact tcaaaacttg tcgcaaatat
    28321 gcttgaagta gctggagtgg atcgtttatt gaccatcgac ttgcatgctg cgcaaattca
    28381 aggattcttt gatattcctg tggatcattt gatgggtgct cctctgattg cagattattt
    28441 tgagcgtcgt ggtatggttg gttctgacta tgtggttgtc agcccggacc atggaggggt
    28501 gactcgtgct cgtaagttgg cagaattttt gaaaacatct atcgctatta ttgataaacg
    28561 tcgtagcgtt gataagatga atactagtga agttatgaac atcatcggta aggttgaagg
    28621 caagacttgt atcttgattg atgatatgat tgataccgct ggaacgattt gtcatgcggc
    28681 agatgctctt gcggaagctg gtgctgttga agtctatgca agctgtacgc acccagttct
    28741 ttctggtcct gctacggaca atatccaaaa atcagctatt aagaaattgg ttgttttgga
    28801 taccatctat ctgccagaag agcgtttgat tgataagatt gagcagattt caatcgctca
    28861 tctcctaggg gatgctatcg tacgtattca tgaaaaacga ccactttctc cacttttcga
    28921 tattgagaaa aaaatttaat gaccaagcct gagatgattc tcaggttttt tcgtcttttt
    28981 tccgaataaa tagatagtag cggtgaatct agtaaagcta gatttaaaac tgtgatataa
    29041 taaaaagaga agaaatatga ctgtacgtca tcagaagttt cagcgaccat catttttgaa
    29101 cagtgatagc acttgaatcg acgctttcta aggagaattc tagtaggtat accagtcgtt
    29161 tcaagataag gaattttaga aggtttttga aagtcatatt tcttcaattg gtttccgcac
    29221 tcagggcaag atggggcgtc gtagtccagt ttggcgatga tttccttgtg tgtatcctta
    29281 ttgatgatgt ttaaaatctg gacattaggg tctttaatgt ctagtaattt tgtgataaaa
    29341 tgtaattgtt ccatatgatt ctttctaatg agttgttttg tcgcttttca ttataggtca
    29401 tatgggactt ttttttacac aaaataggct ccataatatc catagtgggt aaatccccta
    29461 tggatattat ggagccattt tacaacagtg cctcaaattc agatactgac atacctaatt
    29521 gctggctggc aacctcagaa gtcagaagac cttggcgtac tatgtctagg aaggcaaaaa
    29581 gtttcctttc tgcccttcct tcaactttcc cacgctctag tccttgttca aggccttcag
    29641 ccctagcagt ttccaaggca tagtcctgtg ctaacaagac ttgttcttct cgcatatgta
    29701 gttgactaaa cattttcctg tcctcctcgg accagctctt gtagtccagc agttgatttg
    29761 cttgggtaat ggctcgttgc ggttgctggg taaagggctt gttgccgaaa aactccaacc
    29821 atggcttgcg aaccttgtct ttgctggttt ctctgtattt tttaattcca agaatgccat
    29881 cttaaccaga tggttttcct gtccattgtt ggtaatcgcc aatacctcac ctgttgtgtc
    29941 ttcgcgcata ctaaagctat gaaaagccag gtcatctgag aaataattac tatccacgat
    30001 agcaatgacg taaacaggag cgatgtgttt gtagatctag tgagtatcac cttctcgctg
    30061 acgaattttt tcaagatttt gattaacctg actgcacagg taagcccaca agtgattgat
    30121 gaaaaaattc tgatgatgga cttgaatctc aataattact tgagtaccgt tatccaactc
    30181 cgccaagacg tctatactgg tataaaaatc ctgcaccgag taaggcatgg agagtaatac
    30241 gtgaatatcg cttccctcca aaatggtcac attttttgct ggcaagtcca gcatatcgcg
    30301 aataaattga caagtgattt ctggattgct gaatattttc ttagcaatca aatcattagt
    30361 tgggctgatg cccggatgtc tgagaatcct cctattcctc cttctatagt gagttgaaat
    30421 aagatgtgaa taactctatc aggaaagtca aattaattta tagaaatatt ttagcagtca
    30481 aggtgtacta ttatagattc aatatactat attatagcac atttttaaat ctaggtttac
    30541 taaattctct ggctctatct atttattcgg aaaaagtttg aaaaatactt gctctagctc
    30601 ttcccaatgg tattttttga ttctttcctt tataatgggt gtatggataa gaaaaaatta
    30661 ttattgattg atgggtcttc tgtagctttt cgggcgtttt ttgcgctgta tcagcagttg
    30721 gaccgtttta agaatgcggc tggtttgcat accaatgcga tttatggttt tcagttgatg
    30781 ttgagtcatt tgttggagcg ggttgagccg agtcatattt tggtggcttt tgatgcggga
    30841 aagacgacct tccggacaga gatgtatgcg gactataagg gtggtcgggc caagactcct
    30901 gatgagtttc gtgagcaatt tcctttcatt cgtgagttgc tggatcatat ggggattcgt
    30961 cactatgagc tggctcagta tgaggcggat gacatcattg ggacgctgga taagctagca
    31021 gagcaggatg gttttgatat taccattgtc agtggggaca aggatttgat tcagctgacg
    31081 gatgagcata cggtggttga aatttccaag aaaggtgtgg ctgagtttga ggcctttacg
    31141 ccagattacc tcatggaaga aatgggcctc acaccagctc agtttatcga tctcaaggcg
    31201 ctcatgggtg ataagtcgga taatatccct ggggtgacca aagtcggtga aaagacgggt
    31261 attaagctct tgctggagca tggttcgctt gaggggattt atgaaaatat tgatggaatg
    31321 aagacttcta agatgaagga aaatctcatc aatgacaagg aacaggcctt tttgtctaaa
    31381 acactagcga ccattgatac caaggcaccg attgcgattg gtttagagga cttggtctat
    31441 agtggtccag atgttgaaaa tcttgggaaa ttctacgatg agatgggctt caaacagcta
    31501 aagcaggctt taaatgtgtc gtcagctgat gtgtctgaga gtttggattt tactattgtt
    31561 gaccaaatca gtcaagatat gctgagtgaa gagtctatct tccactttga gctttttggt
    31621 gagaattacc atacggataa tttggttgga tttgcctggt cttgtgggga taagctctat
    31681 gccacagaca agcttgagct gttgcaagac ccgattttca aggatttctt agaaaaaaca
    31741 tctctgagag tttatgactt taagaaggtt aaagttcttt tgcaacgttt tggtgtggat
    31801 ttgcaggcgc ctgcttttga catccgtttg gctaaatacc tcctttcgac tgtggaggac
    31861 aatgaaattg cgaccatcgc tagtctttat ggtcagactt acttggttga tgatgaaact
    31921 ttctacggta agggtgttaa aaaggccatt cctgaacgtg agaaattctt ggaacactta
    31981 gcttgtaaac ttgctgtttt ggtagaaaca gagcctattt tacttgaaaa actcagcgaa
    32041 aatgggcaat tagagcttct ttatgatatg gagcaacctc tggcttttgt ccttgccaag
    32101 atggaaattg ctgggattat ggtcaagaaa gagaccttgc ttgagatgca ggctgaaaat
    32161 gagcttgtca ttgaaaaact gactcaagag atttacgagc tggctggtga ggagtttaat
    32221 gtcaactcgc ctaagcagtt gggcgtgctt ctctttgaga aattgggact tcctctagaa
    32281 tacactaaga aaaccaagac aggttattcg acagcagtgg atgttttgga gcgtctcgct
    32341 cctattgctc tgattgttaa gaaaatcctg gattaccgtc aaattgctaa gattcaatct
    32401 acttatgtaa ttggcttgca ggactggatt ttggctgatg gaaagattca tactcgctat
    32461 gtgcaggatt tgacccagac cgggcgtttg tctagtgtgg atccaaactt gcaaaatatt
    32521 cctgcccgat tggaacaggg gcgcttgatt cggaaggctt ttgtgccaga gtgggaggat
    32581 agtgtgctac tcagctctga ctattcacag attgaattgc gcgttttggc gcatatttct
    32641 aaggatgagc acttgattaa ggccttccaa gagggggcag atatccatac ttcgacagcc
    32701 atgcgggtct ttggcattga gcgtcctgat gatgtgactg caaacgaccg tcgcaatgcc
    32761 aaggcagtta actttggagt ggtttatggg atttcagact ttggcttgtc taataatttg
    32821 ggaattagtc gtaaggaagc caaagcctac attgatacct actttgaacg ttttccaggt
    32881 attaaaaact acatggatga agtggtgcgg gaggcgcgtg ataagggcta tgtagagacc
    32941 ctctttaagc gtcgccgtga gttgccagat atcaattcgc gcaacttcaa tattcgtggt
    33001 tttgcggaac gaactgctat caactcacct atccagggtt cggcagcaga tattctcaag
    33061 attgccatga ttcagctgga taaagccttg gttgcaggtg gttatcagac taagatgctg
    33121 ttacaagtgc acgatgaaat cgtccttgaa gtgcctaaat ctgaattggt agagatgaaa
    33181 aaattggtga aacaaaccat ggaagaagcc attcaactca gtgttcctct tatcgcagat
    33241 gagaatgaag gggcaacctg gtacgaggct aaataaaaag ggggctagtc ctcctttttt
    33301 gtagtataat tctgcaaacc ttttcaaaat gtgctatact gatgaaaaag gaggatttct
    33361 atgagtcaag aatttatcaa tccaagtgat ggcgtgattc gtcagtatct cgcaacgagt
    33421 aaaacccttg ctgtggtggg tttgtctgac cgtgaagaaa caaccagcaa tcgagtaaca
    33481 aaggaaatgc aggctcgggg ctataaaatc atcccagtca atcccaaggc ggcaggtggc
    33541 gaaatcttgg gtgaaaaggc ttatgctagc ctcgctgaaa ttccttttcc tgtagatatt
    33601 gtcaatgttt atcgtcgcag tgaatttctg cccgatgtgg cgcgtgattt tctcaaagct
    33661 gatgccaaga ttttttgggc acagctagga cttgaaagtt tagaagcgaa agagattttg
    33721 cgtgatggtg gatgtgatga tatcgtgatg aatcgctgta tcaagagaga acatactcgc
    33781 ttgattgagg aagcataaga aaaaggtagc tgatgggcta ccttttgtgt tatactcaat
    33841 gaaaatcaaa gagcaaacta ggaaactagc cgcgggctgc tcaaaacacc gttttgaggt
    33901 tgcagataga actgacgaag tcagtaacat atatacggca aggcgacgtt gacgtggttt
    33961 gaagagattt tcgaagagtg ttagaaaatg ccgataaggg tctgcatacc aagagtggtg
    34021 aggatgatgg caatccagca gatggctcca agaagaatgg attttccact ggatttgacc
    34081 atagcgacca gattggtttt gagaccgata gcactcatgg ccatgacaat aaggaattta
    34141 gagagttctt tgagaggagt aaagaaacta ctggacacac ctagagaggt gagtagtgta
    34201 gtgaggagag aggcaaggat aaagtaaagg ataaaaagtg ggaagacttt tttcagttgc
    34261 aggctttgct tgttttcttg ttggcgactt tgccagtagg atagaaagag cgtgataggg
    34321 ataatggcca aagtacgtgt gagtttaaca atggttgcag actcgagggt attgctttgg
    34381 taaagactgt cccaagcgct ggcggcagcc gttacagagg aagtgtcgtt gaccgcagtc
    34441 cctgcaaaga gggcgaagcc ttcattggat agatgaagcc aggtgccgag ggttggaaag
    34501 atgagcgcag ccaagacatt gaagaaaaag ataacggaaa tggcttgggc tacttccttt
    34561 tccttagcat caataacggg cgctgtcgct gcaatggcag aacccccaca gatagaagaa
    34621 cctactccaa ccaaggtagc cagttttgta tccagggcaa agaaacgctg gaagaggtag
    34681 gcaataatca gagctattga gatagtggac aggatgacag ggagtgaaga ttggccaact
    34741 gcgaagacct gcgagatatt gagaccaaaa ccaagcaaga caacggcata ttggagcaac
    34801 ttcttggaac taaaggtcaa accagcatcc agttgtttat aggacgagag aaagggatgt
    34861 aggagcatgc ctatgaaaat ggcaaaaacg ggcgcgccaa tcacagggaa gaatcctcct
    34921 aagtaccaag atacgataga aatgagaagg caggccaaga tacctgctcc attttttgat
    34981 agaaatgaca taaaaacctc caaataaaat ctattaccat tatagaccta taaacaggaa
    35041 aagtaaaata gaaagtggaa agctatcctc taatgtattt ttgcggtcgg ggggcttttg
    35101 tagtataata gagatacgtt ttgaaagtag gaggtatcta tggacttaac taagcgcttt
    35161 aataaacagt tagataaaat tcaagtttcg ttgattcgtc agtttgacca ggctatttcg
    35221 gagattcctg gggtcttgcg tttgaccttg ggggaacctg attttacaac gccagaccat
    35281 gtcaaggagg cggccaagcg agcgattgat cagaaccaat cctactatac agggatgagt
    35341 ggtctgctga ctctacgtca ggcagctagt gactttgtta aggaaaagta ccaactggac
    35401 tatgctcctg aaaatgaaat cttggttaca attggggcga cagaggcttt atctgcgact
    35461 ttgacggcta ttttggaaga gggagacaag gtacttttgc cagctcctgc ttatccaggc
    35521 tatgaaccga ttgttaactt agttggggca gaaattgttg agattgatac gactgaaaat
    35581 ggttttgtct tgactcctga gatgttggag aaggccattt tggagcaggg tgataagctc
    35641 aaggcggtta ttctcaacta tccagccaat ccgacaggaa ttacctacag tcgagagcag
    35701 ttagaggcct tggcagctgt tttacgcaag tacgaaattt ttgttgtctg tgatgaggtt
    35761 tactcagaat tgacctacac aggcgaagcc catgtgtctc taggaacgat gttgagagac
    35821 caggctatta ttatcaatgg tttgtctaaa tcgcatgcca tgacaggttg gcgtttgggg
    35881 ctgattttcg ctcctgcggc cttcacatcc cagttaatca agagtcacca atacttggtc
    35941 actgccgcaa ataccatggc gcaacatgct gcggtagaag ccttgacggc tggtaaaaat
    36001 gatgcggagc ccatgaagaa ggaatatatc cagcgtcggg actatatcat cgaaaaaatg
    36061 actgctcttg gttttgagat tatcaaacca gacggtgcct tctatatttt tgctaaaatt
    36121 ccagcgggct acaatcaaga ctcctttgct tttctgaagg attttgctca gaagaaggcc
    36181 gttgccttta tccctggtgc agcctttgga cgttacgggg aaggctacgt ccgcctatct
    36241 tatgcagcca gcatggagac tatcaaagaa gccatgaaac gacttgagga gtatatgaga
    36301 gaagcatgat tcagtctatc acgagtcaag gcttggtgct ttacaatcgc aattttcgtg
    36361 aggatgacaa gcttgtcaaa atttttacag agcaggttgg caaatgcatg ttttttgtca
    36421 aacacgctgg tcagtctaag ctggcgcctg ttattcagcc cttggtgctg gcacgatttc
    36481 tcttgcgaat caatgatgac ggactcagtt acatcgaaga ctatcatgag gtcatgactt
    36541 ttcccaagat taatagtgac ctctttgtca tggcctatgc gacctatgtg gcagctcttg
    36601 cagatgctag tttgcaggac aatcagcagg atgctccctt gtttgctttt ttgcaaaaga
    36661 ctttggagtt gatggaagca ggcttggatt atcaggtttt gaccaatatt tttgaaattc
    36721 aaattttgac tcgatttgga atcagcctca attttaatga gtgtgtcttc tgccatcggg
    36781 ttggtcaggc ttttgacttt tctttcaaat atggagcctg tctctgtcca gagcattatc
    36841 atgaggatga gagacgttgc catctcaatc ccaatatccc ctatctgctc aatcaatttc
    36901 aagctattga ttttgagact ttggagacca tttcgctcaa gcctggaatc aagcaagagc
    36961 tacgccaatt tatggatcaa ctatatgaag agtacgttgg gattcaccta aaatcaaaga
    37021 aatttattga ttccctagca gactggggac aattactaaa agaggaaaag aaatgaaaaa
    37081 aatcgcagta gatgccatgg ggggcgatta cgcacctcag gccatcgttg agggtgtcaa
    37141 tcaagcccta tctgactttt cagatatcga ggttcaactc tacggagatg aagctaaaat
    37201 caagcaatat ctgacagcga cagagcgcgt cagcattatc catacggatg agaagattga
    37261 ttcggatgat gaacctacga gagctattcg gaataagaaa aatgccagta tggtattggc
    37321 agccaaggct gtcaaagatg gtgaagcaga cgctgtcctt tcggctggga atacaggtgc
    37381 tttgttggct gctggattct tcatcgtggg tcgtatcaag aatatcgacc gtcctggact
    37441 tatgtcaaca ttgccgactg tagatgggaa aggttttgac atgcttgacc tcggtgctaa
    37501 tgcagaaaat acagcccagc acctccatca atacgctgtc ctaggttctt tctatgccaa
    37561 gaatgttcgt ggcattgcgc aaccacgtgt tggtttgctc aacaacggaa cagagagtag
    37621 caagggcgac ccgcttcgta aggaaactta tgaattactg gcggctgatg aaagtttgaa
    37681 ctttatcgga aacgtggaag cgcgtgattt gatgaatggt gttgcagatg ttgttgtggc
    37741 agatggtttc acgggaaacg ctgtgctcaa atccatcgaa gggacagcta tgggaatcat
    37801 gggcttgctc aagacagcta ttacaggtgg tggtcttcga gcgaaactag gtgccctcct
    37861 tctcaaggac agcctcagag gtttgaaaaa acagctcaat tattcagatg ttggtggagc
    37921 ggtcttgttt ggtgtcaagg cacctgttgt caagactcat ggctcaagcg atgccaaggc
    37981 tgtttatagt acgattcgcc agattcgtac catgctagaa acagaagtag ttgcccagac
    38041 tgcgcgtgaa ttttcaggag aataaaagag atgaaagaaa aagaaatttt tgacagtatt
    38101 gtgaccatta tccaagagcg acagggagag gactttgtcg tgacagaatc cttgagtctg
    38161 aaagacgact tggatgctga ctcagttgat ttgatggagt ttatcttgac gctggaggat
    38221 gaatttagta tcgaaatcag cgatgaggaa attgaccaac tccaaagtgt aggagatgtg
    38281 gttaaaatca ttcaaggaaa atagcaatcg gagttccaag tcaacggaag tagatggttt
    38341 ttagaaatga gaaatatcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg
    38401 cttatgaaga tatatcctca agcacaaact tccacgtaaa tccagcaaac tcaagccgct
    38461 aacagttgaa gataaagcct gtaatcatgc gctatctaag gagagaagca aggttgagaa
    38521 tatctttgcc aaagtaaaaa cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa
    38581 acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac taggattcta
    38641 gttttgcagg aagtctaata gtaaaaaagt gattagaaaa catctttttt aaaaatagag
    38701 atgattttga aacaaaaaag ctaattcaag acgtttcgat gccaattcaa gatttggatg
    38761 aaaaaaatta atagatactg ttatactaaa cttgtcaagt ttgtaacaag acaaatatta
    38821 aaaataaaaa agaggtattc gttatgaata caaaaaagat gtcacaattt gaaattatgg
    38881 atactgagat gcttgcttga gttgaaggtg gcggatgcaa ttggggagat tttgccaaag
    38941 caggtgttgg aggaggagta gcacgaggtc ttcagctagg aattaaaaca agaacatggc
    39001 aaggtgcagc aactggtgct gcgggaggag ctatacttgg aggtgtggcc tatgaagcga
    39061 catgttggtg gtaattatgg attttaaaag ttttattatt ggtttagtag ttggtatatt
    39121 tggtccttat atggatgatt taattagaaa aaaattttta aagtcttcgg agaagaaaac
    39181 agaaaaatct gttaaaaaat aatcaaaact ataaatgatg aatctgaatc aaaattattt
    39241 tgcgcatgta aagaggagtc ttatagtaac gagtcaaaaa aggagtaact atgaatcgta
    39301 atttagaacg gtgttatcta ttctgactag ggatagatca taccataggt agcttagaaa
    39361 tagcagagac attagaaatt gaagtaataa ataggatgtc gtaagtgtta ctatcaatga
    39421 tttatttgtt tcaagcttgc ctagggtgtc agtaaaaaat cattttcctt tcaatagcat
    39481 atttttagtg ggcaggactc ttgttctgcc tattttttta tccaaaaagt gcagttggga
    39541 gggagatagg ctcatttggg aaggaagtcc agtttttgtt tagtgattgg ggtaagatag
    39601 ttgttatcag atgagtttat attcttcgaa aatcaaattc aaaccacgtc aacgtcgcct
    39661 tgccgtatat atgtgactga cttcgtcagt cctatctaca acctcaaaac agtgttttga
    39721 gcagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt agggaaaagg
    39781 agatgaatat gaaatttggg aaacgtcact atcgtccgca agtggatcag atggactgcg
    39841 gtgtagcttc attagccatg gtttttggct actatggtag ttattatttt ttggctcact
    39901 tgcgagaatt ggctaagacg accatggatg gaacgacggc tttgggcttg gtcaaggtgg
    39961 cagaggagat tggttttgag acgcgagcca ttaaggcgga tatgacgctt tttgacttgc
    40021 cggatttgac ttttcctttt gttgcccatg tgcttaagga agggaaattg ctccactact
    40081 atgtggtgac tgggcaggat aaggatagca ttcatattgc cgatccagat cccggggtga
    40141 agttgaccaa actgccacgt gagcgttttg cggaagaatg gacaggagtg actcttttta
    40201 tggcacctag tccagactac aagcctcata aggaacaaaa aaatggtctg ttctctttta
    40261 tccctatatt agtgaagcag cgtggcttga ttgccaatat cgttttggca acactcttgg
    40321 taaccgtgat taacattgtg ggttcttatt atctgcagtc tatcattgat acctatgtgc
    40381 cagatcagat gcgttcgaca ctagggatta tttctattgg gctagtcatc gtctacatcc
    40441 tccagcaaat cttgtcttac gctcaggagt atctcttgct tgttttgggg caacgcttgt
    40501 cgattgacgt gattttgtcc tatatcaagc atgtttttca cctccctatg tccttctttg
    40561 cgacacgcag gacaggggaa atcgtgtctc gttttacaga tgctaacagt atcatcgatg
    40621 cgctggcttc gaccatcctt tcgattttcc tagatgtgtc aacggttgtc attatttccc
    40681 ttgttctatt ttcacaaaat accaatctct ttttcatgac tttattggcg cttcctatct
    40741 acacagtgat tatctttgcc tttatgaagc cgtttgaaaa gatgaatcgg gataccatgg
    40801 aagccaatgc ggttctgtct tcttctatca ttgaggacat caacggtatt gagactatca
    40861 agtccttgac cagtgaaagt cagcgttacc aaaaaattga caaggaattt gtggattatc
    40921 tgaagaaatc ctttacctat agtcgagcag agagtcagca aaaggctctg aaaaaggttg
    40981 cccatctctt gcttaatgtc ggcattctct ggatgggggc tgttctggtc atggatggca
    41041 agatgagttt ggggcagttg attacctata ataccttgct ggtttacttt accaatcctt
    41101 tggaaaatat catcaatctg caaaccaagc ttcagacagc gcaggttgcc aataaccgtc
    41161 taaatgaagt gtatctagta gcttctgagt ttgaggagaa gaaaacagtt gaggatttga
    41221 gcttgatgaa gggagatatg accttcaagc aggttcatta caagtatggc tatggtcgag
    41281 acgtcttgtc ggatatcaat ttaaccgttc cccaagggtc taaggtggct tttgtgggga
    41341 tttcagggtc aggtaagacg actttggcca agatgatggt taatttttac gacccaagtc
    41401 aaggggagat tagtctgggt agtgtcaatc tcaatcagat tgataaaaaa gccctgcgcc
    41461 agtacataaa ctatctgcct caacagccct atgtctttaa cggaacgatt ttggagaatc
    41521 ttcttttggg agccaaggag gggacgacac aggaagatat cttacgggcg gtcgaattgg
    41581 cagagattcg agaggatatc gagcgcatgc cactgaatta tcagacagaa ttgacttcgg
    41641 atggggcagg gatttcaggt ggtcaacgtc agagaatcgc tttggcgcgt gctctcttga
    41701 cagatgcgcc ggtcttgatt ttggatgagg cgactagcag tttggatatt ttgacagaga
    41761 agcggattgt cgataatctc atggctttgg acaagacctt gattttcatt gctcaccgct
    41821 tgactattgc tgagcggaca gagaaggtgg ttgtcttgga tcagggcaag attgtcgaag
    41881 aaggaaagca tgctgatttg cttgcacagg gtggctttta cgcccatttg gtcaatagct
    41941 agaaagagga gaggatgaaa ccagaatttt tagaaagtgc ggagttttat aatcgtcgtt
    42001 accataattt ttccagtagt gtgattgtac ccatggccct tctgctcgtg tttttacttg
    42061 gctttgcaac tgttgcagaa aaggagatga gcttgtccac tagagctact gtcgaaccta
    42121 gtcgtatcct tgcaaatatc cagtcaacta gcaacaatcg tattcttgtc aatcatttgg
    42181 aagaaaataa gctggttaag aagggggatc ttttggttca ataccaagaa ggggcagagg
    42241 gtgtccaagc ggagtcctat gccagtcagt tggacatgct aaaggatcaa aaaaagcaat
    42301 tggagtatct gcaaaagagc ctgcaagaag gggagaacca ctttccagag gaggataagt
    42361 ttggctacca agccaccttt cgcgactaca tcagtcaagc aggcagtctt agggctagta
    42421 catcgcaaca aaatgagacc atcgcgtccc agaatgcagc agctagccaa acccaagccg
    42481 aaatcggcaa cctcatcaat caaacagagg ctaaaattcg cgattaccag acagctaagt
    42541 cagctatgga aacaggtgct tccttggcca gtcagaatct agcctactct ctttaccagt
    42601 cctacaagtc tcagggcgag gaaaatcccc aaactaaggt tcaggcagtt gcacaggttg
    42661 aagcacagat ttctcagtta gaatctagtc ttgctactta ccgtgtccag tatgcaggtt
    42721 caggtaccca gcaagcctat gcgtcagggt taagcagtca attggaatcc cttaaatccc
    42781 aacacttggc aaaggttggt caggaattga cccttctagc ccagaaaatc ttggaggcag
    42841 agtcaggtaa gaaggtacag ggaaatcttt tagacaaggg gaaaattacg gcaagtgagg
    42901 atggggtgct tcatcttaat cctgagacca gtgattctag catggttgca gaaggtgccc
    42961 tactagccca actttatcca tctttggaaa gagaagggaa agccaaactc acagcctatc
    43021 taagttcaaa agatgtagca agaatcaagg tcggtgattc tgttcgctat actacgactc
    43081 atgatgccgg gaatcaactt tttctagatt ctactattac aagtattgat gcgacagcta
    43141 ctaagactga gaaagggaat ttctttaaaa tcgaggcgga gactaatcta acttcggagc
    43201 aggctgaaaa acttaggtac ggggtggaag gccgtctaca gatgattacg ggcaagaaaa
    43261 gttacctacg ttattatttg gatcaatttt tgaacaaaga gtaatgttcg tgtttttaga
    43321 gttaaataat ttttaaactg tgagaaagat tcttcttgca gttttttctt tacaattttt
    43381 gaaaaacatc tgctatttat tcggttgaat tcttgtgttt tttggttttt tgtggtaaaa
    43441 tgtgctcaag taatacgaaa ggcgaacttt aaaatgtcaa aacaattgat ctattcggga
    43501 aaagctaaag atatctatac aactgaggat gaaaatctta ttatttcaac ttacaaggac
    43561 caggcgactg ctttcaacgg tgtcaagaag gagcagattg caggtaaggg agtcttgaat
    43621 aatcagattt catcttttat ttttgagaaa ttaaatgcgg ctggtgtggc gactcacttt
    43681 gtggagaaac tttcagacac ggaacaactc aataaaaagg ttaagattat tcctttggaa
    43741 gtcgtgctcc gcaactatac tgctggttcc ttttcaaaac gttttggtgt ggatgaggga
    43801 atcgccttgg agactccgat tgtcgaattt tactacaaaa atgatgattt ggatgatcca
    43861 tttatcaatg atgagcatgt gaaattccta cagattgcgg gtgaccagca gattgcctac
    43921 ttgaaggaag aaacgcgtcg tatcaatgaa ctattgaaag tctggtttgc tgagattggg
    43981 cttaaattga ttgactttaa gctagagttc ggttttgaca aggatggcaa gattatcttg
    44041 gcagacgaat tttcaccaga taactgccgc ttgtgggacg ctgatggcaa ccacatggat
    44101 aaggatgttt tccgtagagg attgggagaa ctaaccgacg tttatgagat tgtttgggaa
    44161 aagttgcagg gtttaaaata acaacctcaa ggctgtttgg gaatattgca agagctgaaa
    44221 taaaggaata agaattgatg gataaacgta tttttgttga aaaaaaggct gattttcagg
    44281 tcaagtcaga gagtttggtt agagagctcc agcacaacgt gggactgtca agcttgaaaa
    44341 gtattcgtat tgtgcaagta tatgatgtat ttgacttggc tgaggacttg tttgcacctg
    44401 cagagaagca cattttctct gagcagggaa ccgaccatgt tttagatgaa gtatctgtgc
    44461 aggcggatct tgctaactat gctttctttg ccattgaaag tctgccaggg cagtttgacc
    44521 agcgtgcagc ttcgtcacag gaagccttgc ttttgttggg aagttcgagt gacgtgacag
    44581 tcaacacagc ccaactttac ttggtgaata aagatattga tgcgactgag ttggaagctg
    44641 tcaaaaacta cctgctcaat ccagttgatt ctcgtttcaa ggatatcacg acagggattg
    44701 ccaagcagga gttttcagag tcagacaaga ccattccaaa attgactttc tttgaaagct
    44761 atacagcaga agactttgct cgctacaagg ccgagcaagg gatggccatg gaagtggatg
    44821 atttgctctt tatccaagac tactttaagt caatcgggcg cgtgccaact gagactgaac
    44881 tcaaggtttt ggacacttac tggtctgacc actgccgtca tacgactttt gagacagagt
    44941 tgaaacacat cgacttttca gcttctaaat ttcaaaagca attgcagtca acctatgaca
    45001 agtatattgc catgcgcgag gagttaggtc ggtctgaaaa accacaaacc ttgatggata
    45061 tggcgactat tttcggtcgt tatgagcgtg ctaacggacg attggatgat atggaagtct
    45121 ctgacgaaat caatgcctgc tcagttgaaa ttgaagtgga tgttgatggt gtcaaggaac
    45181 cttggctcct catgtttaaa aatgaaaccc acaaccatcc aacagaaatt gagccatttg
    45241 gtggagcggc tacctgtatc ggtggagcta ttcgtgatcc gttgtcaggc cgttcctatg
    45301 tttaccaagc catgcgtatt tcaggtgctg gtgatattac agcaccgatt tcggaaactc
    45361 gtgctgggaa attgccacaa caagtcattt ctaaaacagc agctcatggt tattcttcat
    45421 atggtaacca gattgggctt gccacaacct acgttcgtga atacttccac ccaggctttg
    45481 tagctaaacg tatggaactt ggtgccgttg ttggtgcggc tcccaagggc aatgttgtcc
    45541 gtgaaaaacc tgaagcaggt gatgtgatca tccttctcgg aggcaaaaca ggtcgtgatg
    45601 gtgtcggtgg tgcgacgggc tcttctaagg ttcaaacagt tgagtctgta gagactgctg
    45661 gtgctgaggt tcaaaaagga aatgccatcg aagaacgcaa gattcagcgc ctcttccgta
    45721 atggcaatgt cactcgtctg atcaagaagt ccaatgactt tggggcaggc ggcgtctgtg
    45781 tggctatcgg tgaattggca gacggtcttg aaatcgacct caacaaggtg cctcttaaat
    45841 accagggctt gaatggtaca gaaattgcca tctctgaatc acaagaacgg atggcggtcg
    45901 tggttcgtcc tgaagatgtg gatgccttcg ttgccgaatg taacaaagaa aatattgatg
    45961 ctgttgtggt ggcgatagta actgaaaaac caaatcttgt catgcactgg aatggtgaga
    46021 caatcgttga cttggagcgt cgtttccttg acaccaatgg tgtgcgcgtg gttgtcgatg
    46081 ccaaagttgt ggacaaggat gtcaaactcc cagaagagcg tcaaacatct gctgaaacac
    46141 tggaatcaga tacccttacg gttctatctg acctcaacca tgcaagtcaa aaaggattac
    46201 agactatctt tgactgctct gttggacgct caacggttaa tcacccactt ggtggtcgtt
    46261 accaactcac accaactgag gcatctgtgc agaaattgcc agttcaacac ggtgtgactc
    46321 atactgcgtc ggtcattgct caaggtttca acccatatgt agctgaatgg tctccatacc
    46381 acggtgctgc ttatgcggtt atcgaagcaa ctgctcgttt ggtggctgct ggtgccaact
    46441 ggtccaaggc tcgtttctct taccaagagt atttcgagcg tatggataaa caagcagagc
    46501 gtttcggtca gccagtagct gctcttctag gttctattga agcacaaatt cagcttggct
    46561 tgccatctat cggtggtaag gactccatgt ctggtacctt tgaagaattg accgttccgc
    46621 caaccttggt tgcctttggg gtgacgacgg cagatagccg taaggtgctc tctccagaat
    46681 ttaaagctgt tggggaaaat atctactaca tcccaggtca agccctctct gcagagattg
    46741 attttgactt gattaagaaa aattttgctc agtttgaagc catccaagct gaccataaag
    46801 tgacatctgc atcagctgtc aaatacggtg gtgtagttga aagtttggct cttgctacct
    46861 ttggaaacta tattggtgca gaggtgacct tgcctgaact tgaaacagct ttgacagctc
    46921 aattaggcgg ctttgtcttc acatctcctg aagaaattgc tggagtagag aaggttggac
    46981 aaacgaaagc agactttaca ctgactgtca acggtgtgaa gctagatgga cacaagcttg
    47041 acagtgcatt tcaagggaca ttggaagaag tttacccaac agaatttacc caagcgaaag
    47101 aactagaaga agtaccagct gtggcatcag atgttgtgat taaagccaaa gaaaaggttg
    47161 aaaaacctgt ggtttacatc ccagtctttc caggaaccaa ctcagaatat gattcagcta
    47221 aggccttcga aaaagaaggt gcagaggtca atttggtgcc attcgtgacc ttgaatgaag
    47281 aagctattgt caagtcagtt gaaactatgg ttgacaatat cgacaagact aatattctct
    47341 tctttgctgg tggattctcg gctgcggatg aaccagatgg ttcagctaag tttatcgtca
    47401 atatcctgct taatgaaaaa gtgcgtgtgg ctattgatag ctttatcgcc cgtggtggtt
    47461 tgattatcgg tatttgtaat ggattccaag ccttagtcaa atcgggtctc ctaccctacg
    47521 gaaactttga agttgctaac agtactagcc caaccctctt ctacaatgat gccaaccaac
    47581 acgtggccaa gatggtggaa actcgcattg ccaataccaa ctcaccatgg ttggctggtg
    47641 tgcaagtggg cgatatccac gctattcctg tttcgcacgg tgaagggaag tttgtcgtga
    47701 cggctgagga atttgcagag ctccgtgaca atggacaaat tttcagccaa tacgttgact
    47761 ttaacggtaa accaagtatg gattctaagt acaatccgaa tggttctgtc catgccatcg
    47821 aaggaattac cagcaagaat ggtcaaatca tcggtaagat gggccactca gaacgttatg
    47881 aggacggtct tttccaaaat atcccaggca ataaagacca gcacctgttc gcgtcagcgg
    47941 ttaaacattt cactggaaaa taagacttac agattttcta atagatagta tcagtaatgt
    48001 aaaagtcatg taaatctagc tcttgatgat tacaaatgaa aattaggtat aaaaaatgac
    48061 atacgaagta aaatctctta atgaagaatg tggtgttttc ggtatttggg gacatccaga
    48121 tgctgctaag ttgacctatt ttggactcca cagtcttcag caccgtggtc aagagggggc
    48181 aggaatcctc tccaatgacc aaggaaaact aaagcgccat cgtgacatgg gacttttatc
    48241 agaagtcttc agaaatcctg ctaatttgga taaattgaca gggactggtg cgattgggca
    48301 tgtgcgttat gcgactgctg gcgaagcttc tgtagataac atccagccct tcctcttccg
    48361 ttttcacgat atgcagtttg gcttggctca taatgggaat ctgaccaatg cagcctctct
    48421 caagaaagaa ttggaagata gaggagcaat tttcagtgcg acttcggatt cggaaatctt
    48481 ggctcatctc attcgtcgca gtcataatcc tagcctgatg ggcaaaatca aggaagcgct
    48541 cagccttgtc aaaggtggtt ttgcctatat cttgctgttt gaggacaagt tgattgcggc
    48601 tcttgacccc aatggtttcc gtccgctttc tatcgggaaa atggctaatg gagcagttgt
    48661 tgtatcttct gaaacctgtg cttttgaggt tattggtgcc gagtggattc gtgatttgaa
    48721 gccaggtgag attgtgatca ttgatgacga gggcattcag tatgacagct atacagatga
    48781 tacccagttg gcgatttgtt ctatggagta tatctacttt gctcgccctg attctaatat
    48841 ccacggtgtc aatgtccata cggcacgtaa gagaatggga gcgcaattgg cgcgagaatt
    48901 taagcatgag gcagatattg tagttggtgt gcccaattct tccctaagcg cggctatggg
    48961 atttgcggaa gaatcaggct taccaaatga aatgggtctg atcaaaaacc aatacaccca
    49021 gcgaactttt atccaaccga ctcaagaatt gcgggagcaa ggagtgcgga tgaaactgtc
    49081 tgctgtttcg ggtgttgtca aaggcaaacg tgtggtcatg gtggatgatt ccattgtacg
    49141 tggaacaacc tctcgtcgta tcgttcagct cttgaaagaa gcgggtgcga ctgaggttca
    49201 cgttgccatt ggaagtcctg cactagcgta tccatgtttc tacgggattg atatccagac
    49261 ccgtcaggag ctgattgcag ccaatcatac ggtcgaagaa actcgccaaa tcattggtgc
    49321 ggacagtatg acttatcttt caattgatgg cttgattgag tcgattggta tcgaaacaga
    49381 tgcgccgaac ggtggtctct gtgtcgctta ctttgacggt gactacccaa cgcctctcta
    49441 tgactacgaa gaagactatc gtagaagttt ggaagaaaag accagttttt acaagtaggc
    49501 gacagattct ccattaaaga aaaggaaaaa acaaatgaca aataaaaatg catatgccca
    49561 gtcgggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa agcacgtggc
    49621 ccgtacggag cgtgcaggtg tcatgggagc tcttggtggc tttggtggta tgtttgacct
    49681 ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg tcggaaccaa
    49741 gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact gtgtggccat
    49801 gtgtgtcaac gacatcattg ctgcaggtgc ggaacccctc tattttctcg actacgtagc
    49861 gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg cagaaggttg
    49921 tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg
    49981 cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat
    50041 tgacggttca aaggtggtag agggagatgt tcttctcgga cttgtttcaa gtgggattca
    50101 ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct
    50161 accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc gtatctatgt
    50221 caaggctgtc ttgccgctca tcaaagaaga gttggtcaac ggcattgccc acatcacagg
    50281 tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg ctgaaattga
    50341 tgaaagcaaa gttccagtgc ttccaatttt caaagccctt gaaaaatacg gtcagattaa
    50401 acacgaagaa atgtttgaaa tcttcaatat gggtgtggga ctcatgttgg cggtcagccc
    50461 tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat
    50521 cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt ttttgcctct
    50581 ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt tgtcttttca
    50641 gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct
    50701 tttgaactca aggagtttga gagcaaggca gactacgaag cagcccttgt cgaactcttg
    50761 gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatagt tggaccaacc
    50821 ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt gccagaattt
    50881 ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc
    50941 attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca
    51001 cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc agagtacagg
    51061 ttgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga ttcatatgat
    51121 atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg
    51181 taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg atgttattaa
    51241 cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt ttcttagctc
    51301 caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga aaaattgttt
    51361 ttgctgaaat gttatttaat ctgatttcct ttattccatt aggtgtttgt ttccctttga
    51421 taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt agtttattgt
    51481 ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacggat ttgactttaa
    51541 atacgctagg tgtctgtgta ggcttactga tttatcaaat ttttataaga gtgttcaaat
    51601 cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt gcttatcttg
    51661 ttttactgtt actgcattta attggtgttt aactaatgat taaaaaggag aatataatga
    51721 ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt gcccaagaac
    51781 tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc cttgataatg
    51841 ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg atggacggtc
    51901 gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt gacttggata
    51961 gccacttgga agcggctaag gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc
    52021 tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat gcagttgaaa
    52081 atatcgatat tggtgggccg tctatgcttc gttcagcagc gaaaaatcat gccagtgtta
    52141 cagttgtggt agatcctgct gactacgctg tggttttgga cgaattggca gcaaacggcg
    52201 aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac acagcggctt
    52261 atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag cctgaaaaac
    52321 tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct caacaagacg
    52381 cggactttta ccagaaagct ttgcctacag actactccat tgcttcagcc aaacagctca
    52441 acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc cgtatcatcc
    52501 gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca tgtggaattg
    52561 gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac ccagtgtcta
    52621 tctttggtgg gattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc
    52681 acggcgtttt cctcgaaatc atcattgcac caagctatac ggatgaagcg ctagccattt
    52741 tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct caaaaggcta
    52801 gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa aatcaagacg
    52861 tggtcaagga aagcccagct gactggcaag tggtgaccaa acgtcagcca actgagacag
    52921 aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca aatggtatta
    52981 tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac cgtgtggctt
    53041 ctgttcgcct tgccattgac caagccaaag atcgtctgaa cggggcggtc cttgcttcag
    53101 atgccttctt cccatttgcg gataacgtgg aagaaatcgc caaagcagga attaaggcca
    53161 tcatccagcc cggtggctct gtccgtgacc aagaatccat cgaagcagcg gataaatacg
    53221 gcttgactat ggtctttaca ggtgtgagac attttagaca ttaagaagat aaaagggaag
    53281 aaaacagttt ctttcctttt ttggcttaaa atgctaactg aaacaagatt aaaacgaact
    53341 tttttgatat aatattggta aataattcgc aaaagaggtt gaggaatgaa actgcttgtt
    53401 gtcggttcgg gtggtcgtga gcatgcgatt gctaaaaagt tacttgaatc aaaagacgtt
    53461 gaaaaagtct ttgtagctcc tgggaatgat gggatgactc tggatggttt ggaattggta
    53521 aatatctcta tttccgaaca ttctaaattg attgacttcg caaagaccaa tgatgttgct
    53581 tggaccttta tcggtccaga tgatgccctt gctgctggta tcgtggatga ttttaaccaa
    53641 gctgggctta aggcctttgg tccgactagg gctgcagcgg agctggagtg gtccaaggat
    53701 tttgccaagg aaatcatggt caaatatggt gtttcgacag cagcctatgg cacattttca
    53761 gatttcgagg aagcaaaggc ctatatcgaa aagcatggtg cgcctatcgt agtcaaggcg
    53821 gatggcttgg cgcttgggaa gggtgtcgtc gtttctgaga cggttgagca agcggtcgaa
    53881 gccgctcatg agatgctttt ggacaataaa tttggtgact caggtgcgcg cgtggttatt
    53941 gaggaattcc ttgaaggaga ggaattttca ctctttgcct ttgttaatgg tgataagttc
    54001 tacatcatgc caacggctca ggaccacaaa cgtgcctacg atggcgacaa agggcctaac
    54061 acgggtggta tgggtgccta tgcgccagtt ccacacttac cacagagtgt agttgataca
    54121 gcggttgaca ccattgtcaa gccagttcta gaagggatga ttaaagaagg tcgcccttat
    54181 ctgggagttc tttacgcagg gcttatcctg acagctgatg gaccgaaagt cattgagttc
    54241 aacgctcggt tcggagatcc agaaactcag attatcttgc ctcgcttgac ctctgacttt
    54301 gctcaaaata tcacagatat cctggatagc aaggagccaa atatcatgtg gacggacaag
    54361 ggtgtgactc tgggtgtggt tgtcgcatcc aagggctacc cgctagacta tgaaaggggc
    54421 gttgagttgc cagccaagac agaaggcgat gtcatcacct actatgcagg ggctaagttt
    54481 gcggaaaata gcagagcact gctctcaaac ggcggacgag tttatatgct cgttaccaca
    54541 gcagataccg tcaaagaagc ccaagccagc atctaccaag aactatacca acaaaaaata
    54601 gaaggactct tctaccgaac agatatcgga agcaaggcaa ttaagtaaag atataagaat
    54661 aacgcgccgt agtcgccaaa cacgataatg gtcgtcgtgg tgaaaagacc agaacagtga
    54721 atgttctggt cagggggaaa cttggagacc gtaggctcaa agtttaggaa tgaaaccgaa
    54781 ggtttgcttc cgcctccatc acctaagacc attatcaaaa agaaaaataa aaattcacaa
    54841 aatacgttaa tgatcgtatg gtttgcgagc gttagcgagc taatatagaa caatcaccgc
    54901 cgttgtgaaa gaacgattgg atgataatcc aatcgttcag ggaaattgga agaccttggg
    54961 tttccaattt aggcatgaga cacctttggt ggctgctgcc gtccctcaca agctaaggtg
    55021 attgttgaaa aagaggaaaa aggagaagaa atgaaaccag taatttccat catcatgggc
    55081 tcaaaatccg actgggcaac catgcaaaaa acagcagaag tcctagaccg cttcggtgta
    55141 gcctacgaaa agaaagttgt ttccgcacac cgtacaccag acctcatgtt caaacatgca
    55201 gaagaagccc gtagtcgtgg catcaagatc atcatcgcag gtgctggtgg cgcagcgcat
    55261 ttgccaggca tggtagctgc caaaacaacc cttccagtca ttggtgtgcc agtcaagtct
    55321 cgtgctctta gtggagtgga ttcactctat tctatcgttc agatgccggg tggggtgcct
    55381 gttgcgacca tggctatcgg tgaagctgga gcgactaacg cagctctctt tgccctccgt
    55441 ctcctctctg tagaagataa gtccattgcg gatgcacttg ccaactttgc tgaagaacaa
    55501 ggaaaaatcg cagaggagtc gtcaaatgag ctcatctaaa acaatcggaa ttatcggtgg
    55561 cggtcaactg ggtcagatga tggccatttc tgctatctac atgggccaca aggttatcgc
    55621 gctggatcct gcggcggatt gcccggcctc tcgcgtggcg gaaatcattg tggcacctta
    55681 taacgatgtg gacgccctcc gtcagttggc agaccgttgc gatgtcctca cttatgagtt
    55741 tgaaaatgtc gacgctgacg gtttggatgc cgttatcaag gatggacaac tccctcaagg
    55801 aacagatctg ctccgcattt cgcaaaatcg tatttttgaa aaggactttt tgtcaaacaa
    55861 ggctcaagtc actgtggcac cctacaaggt cgtgacttct agcctagact tggcagatat
    55921 cgacttgtcg aaaaactatg tcctcaagac tgcgactggt ggctacgatg gtcatggaca
    55981 aaaggttatt cgttcagaag cagacttgga agcagcctat gcgctagcag actcagcaga
    56041 ctgcgtcttg gaagaatttg tcaactttga ccttgagatt tctgtcatcg tgtcaggaaa
    56101 tggcaaggag gtgacgtttt tcccagttca ggaaaatatc caccgcaaca atatcctgtc
    56161 taagaccatc gtaccagccc gcatttctga aagtctagta gacaaggcta aagctatggc
    56221 agtgcgaatc gcagaacaac tcaacttgtc tggaactctc tgtgtggaaa tgtttgcgac
    56281 tgatgatgac gttattgtca atgaaatcgc cccacgacca cataactctg ggcactattc
    56341 tattgaagcc tgtgatttct ctcagtttga cacccatatt ctcggtgttc tcggagcacc
    56401 attaccagtc atcaaactcc atgcgccagc cgttatgctt aatgtcctcg gtcagcatgt
    56461 cgaggctgct gagcaatatg tgacagaaaa ttcaagcgcc cacctccaca tgtatggtaa
    56521 aatagaagcg aagcacaacc gcaagatggg acatgtgacc ttgtttagtg atgtaccgga
    56581 tagtgtggat gagcttgggg aagggattga tttttaggac aagtctatga tacaaattat
    56641 cgttaataca tttattgaaa aggataagac tggagcagtt gttgaagtgt tgtatgccag
    56701 tgctgaccaa gataaggtaa aagctaaata tgaagaacta gctgcacaat accccgaaaa
    56761 ttatttagct atctatgatg taccgctgga tacggatttg aatacactag atcattaccc
    56821 gtctgtgttt attgaaaaag aggagtttga gtagaaatct tggtttacct agatagctta
    56881 ttcccaacag cttaagaaga aaggaaaaat taacacatga tcaaccgtta ctctcgccct
    56941 gagatggcga atatttggag tgaagaaaat aaataccgtg cttggcttga ggtggaaatc
    57001 ctctctgacg aggcatgggc tgagttgggg gaaatcccta aggaagatgt ggctttgatt
    57061 cgcaagaagg cggactttga catcgaccgt attttggaaa ttgagcagga gacgcgccac
    57121 gatgtggtgg ctttcacgcg tgcggtttct gagactcttg gtgaagagcg caagtgggtt
    57181 cactatgggt taacttctac cgacgtggtg gatactgctt atggttacct ctacaagcag
    57241 gccaacgaca tcatccgtcg tgaccttgaa aacttcacta atatcatcgc tgacaaggcc
    57301 aaggagcaca agttcaccat catgatgggg cgtactcatg gtgtgcacgc tgagccgaca
    57361 acctttggtc ttaaattggc aacttggtac agcgaaatga aacgcaatat cgagcgtttc
    57421 gagcatgcag ctgctggtgt agaagctggt aagatttctg gtgcggttgg gaactttgcc
    57481 aatatcccac catttgtaga ggagtatgtc tgcgataaac ttggcatccg tgcccaagaa
    57541 atctctacac aagtccttcc tcgtgacctt cacgctgagt actttgcggt tcttgccagc
    57601 attgcgactt caatcgaacg tatggcgact gagattcgtg gtctacaaaa atctgagcaa
    57661 cgcgaagtag aagagttctt tgctaaaggg caaaaagggt cttcagcaat gcctcacaaa
    57721 cgcaacccaa tcggttctga aaatatgact ggtctggcgc gtgtcattcg tggtcacatg
    57781 attacggctt atgaaaacgt cgctctctgg cacgaacgcg atatttctca ctcatcagct
    57841 gagcgtatca tcacaccaga tacgaccatt ttgattgact acatgctcaa ccgttttgga
    57901 aatatcgtca agaacttgac agtcttccca gaaaatatga tccgaaacat gaactcgact
    57961 tttggtctta tctttagcca acgggctatg ttgacattga ttgaaaaagg catgacccgt
    58021 gagcaagcct atgacttggt gcaaccaaaa acagcctact cttgggacaa ccaagtagac
    58081 tttaaaccac ttcttgaggc agattcagaa gtaacatcac gtctcactca agaagaaatc
    58141 gatgaaatct tcaacccagt ttattacacc aaacgagtgg atgatatctt tgaacgtctt
    58201 ggactaggtg attaattaaa aaataaacag cgagcttcaa tctcgctgtt tattttttat
    58261 cgaaaagact tagtcttctt ttcttttagt gagtccatag gctgctagtg tggacatgag
    58321 tcctgcgact actagtcctg cagaatcgtg agttcctgtt tcaggaagtt ttttctctgt
    58381 taccacagga gctggatctt gaggaagagc tttgctttcc tcagcgggag cagttgatgg
    58441 agctggttgg cttgggattt ctagttttgg tttttcttca gcaatagcgg cttgtccgtt
    58501 ttcatcgcct acatgtgtta ccatagttcc gacttcgact atttgagtaa cggcttcctg
    58561 tgctacgaca ctatttacaa gtgttttcac ttccttacca tcggcagaag tgctcacaga
    58621 gtagaagttg ctacgatgtc cattgacgcc cttagtaatg acttgtgttt ttcctttgag
    58681 taagagtgga ttttcacgag tcactgtggt aaatggaatt tcttcttttt ggatatccag
    58741 tctaggtttt acctcagtag ttggtgcaag accactttca tcacccttgt gagttacagg
    58801 agcgccaact tcaaccactt ggtttataac ttctttggtt acctggctat caaggactgt
    58861 ttctgttgtt tttccatttt cagtgagtac agagatgtaa tgagttcgtt cacctttgac
    58921 tcctgctgtg ataatatttt cctgaccagc tgggaggtta ggattttctt tcttgataac
    58981 ttcaaatgga atttcttcag ttcttgtgat gagttctggt ctggtttcaa cattggcagc
    59041 cacttcattt tcatccaggc ttcctgaatg agttgcagct ggtttgaggc cttgaagagc
    59101 ggcttttagg ttggctacaa gtgtgtcaag ctcagcttgt ttattacggt tgaggttgta
    59161 atttagagct gttttagctg cgtcaagggc ctcaagactt tctttactat atccttctaa
    59221 gtttgtagga attttagcta attcttcgcg gagagcatta taattagcac ggaagtagtc
    59281 tttgttgtgg tctgcaaagg cagtcatgag ttcaaagatt tcctcttcct tgtactcagc
    59341 gcttggtcta tctgcccaga ttgaaagcat acttccgact gttggaagat ctacttcagg
    59401 atatttggta gaagctagtt gattgaatgg tgtttttcca gtattctcaa tagctttctt
    59461 gaggaaacca ccaccatctt ctggtttttg accaagaatg tagtaccagt caccgttggt
    59521 attcaagaat ttatagcctt tgcttgctag gtattgaggt gatgcgaggt tatatcccca
    59581 ccagccttta gaccagtaag aaatcaagac atctttgtca aactgaacat cgtccttgtc
    59641 ttcatagtag aagccatcgt tgaaggccat tggttgaagc cctctttctt tggccatagc
    59701 tgcgagggtg ttggcatatt cggcaaattt gccatagagt tgataccact tgaggtagta
    59761 ccagccttgg gcactagtcg catcgttggc gtattcgtca gtaccaaagt tgaaaatctt
    59821 tgttttacct gcaaagaagt ccatgtattt accgatgagg gcttttacaa agttcatcgc
    59881 ttcttcgttt ttcaagtcca tagttgtttt tgaaacttta tcaaagtggg cttgaggatt
    59941 tttaatacct aatttttcca tggcaaccag catagcatcc atgtgacctg gactgttaat
    60001 agctgggatg agaccgatgt ccttagattt agcgtattca attagctctg ttacttctgc
    60061 ctgtgttagt gcagtaccgt ttggatcgtc gtagtaagct ttagttcctt cgataatagc
    60121 ttttttaacg tcatcactag cataggtttt tccgttggca gtaatggtca tatcatcgag
    60181 tagaaagcga agtccgtcat ttcctagaag gagatggaca tcagaatatc cgagctcact
    60241 ggccttgtct acgatgcgtt tgagctggtt cagagtaaag tatttgcgtc cagcatcgat
    60301 tgagattacc ttgtttttgg caagtttttc aacctcacgt ttagcttctt cttcttttag
    60361 agcttcaggc gtgagggtca agttgttgac agtttcttga agtttagcaa tggcttgatc
    60421 aatcgtatct tgttgggcac ggctaaggtt gctatcgaga gagcgaatag ctttttcagc
    60481 ttcttttacg gccgtgacgc tttctgcagt ataacggttc aggtcttttg gtacctcgtt
    60541 aagtgcttgc tctgcagatt cataatcagc tgcgaagtat tcagcgttgg catttgcaaa
    60601 atgacgcatg agtttgaaga ggcgtgatgg tgaataacgt gcagatggag tgtcagccca
    60661 agcagctacc ataccaccga tgattgggat atcagctcct tctgtttttg gtacagaagt
    60721 gattggtgtg tttttaatac cattgagccc ctgatcgaga ttgtaccagc cttggccatc
    60781 agcgtttcgt ccaagaacgt agtaccaagc atcattggta ttaaggattt ggtgaccttt
    60841 ttcagctagt agtttagaag aagcgacatc gtagcctccc caaccaccag tccacataga
    60901 aacgatgatg tctttgtcaa aactaccaaa gcttgtgtcg ctattgtagt agataccgtc
    60961 gttaaaagcc attggtttga gaccgtgcga ttttacaata cgagcgaggt cattggcgta
    61021 ggcaataaat ttttcatagc cttttacagg gtagccttcg tttggatagt atttatcagc
    61081 ttgaagcaca ctccaacctt tagcatctgt cgcatcattg gcatattcat caagtccgat
    61141 gttgaagatt tcagtctttt tcgcgaaata agcagcatac ttgtcgataa gggcttttgt
    61201 aaaagcgaca gcttgttcgt tgtcaagatc gacagtacgg gctgatttct tcccaaaata
    61261 gctaaagtta gggttttgga ttcccaattc tttcatggca ttgagaatcg catccatgtg
    61321 tccaggacta tttactgtcg gaatgagacc gataccttta tctttggcat agttaatcag
    61381 atctgtcatt tgactttctg ttaagtgatt gccgtttgga tcgttgtaat aatcatttgt
    61441 acctttttca atggcgcgtt tgacatcgtc actggcatag gtcttgccgt tagctgtgat
    61501 gctcatatcg tccaacatga aacggagtcc atcatttccg actaataggt gtaaatcagt
    61561 gtagccataa tgtttcgctt tatcgatgat ttccttgagt tgttctggtg agaaatattt
    61621 acgtccagca tcaatagaaa caattttctt tttcgctagt ttttcattta cagttgcagc
    61681 acgttccttt cctgcctctg tttccggttt gtcagcctct gctttcgctt catctttttt
    61741 agctggttta tccttgtcag tcttgtctgt atttgactct ttagaatcaa cctctttcgc
    61801 ttcttccttt ttagggctag cttcttctgc ctttttatta gcagtttctt tttcagcaga
    61861 agttggagtt accacttctg ctttatcact aggagttgaa ctaacttcct cttgtggttt
    61921 ttcttctgtt tttggaagac tagctacctt atcagtagct ggagtttctg tttctacagt
    61981 ttttggagct tctggttgaa gcactgcttt aggtgtttcc tcagtccgat tttcggatga
    62041 ttgaggggaa tcagaaaccg tatggatggt cggttggttt tctgtagtag taggagtaac
    62101 tccatcggct gcaacagtct gtgcttggaa ggcaaatcca attagaacag aagctgctcc
    62161 tacagcgtat ttacgaatag aaaaacgctg ttgtttttca tgtttcattg caaaacctcc
    62221 tgattgcatt gttatattga tagcgattat ataaatcaac gcctttattt tatttcttat
    62281 attaacgaga gtcaagagga gatgacaaaa aactataata agtataaaaa aatataaaat
    62341 ttaaacttaa gatttcagat tggtcggaaa aaatacgtat atatatctag tataattttt
    62401 ggttctattt ctataaaata ttccacaaat tatagaattt tccaaaaata ggtaagcgct
    62461 acctttttgg tgtggtataa taagcataga aaaagcccaa gcgattagct caggctttct
    62521 tcttagtgat cacggtcaca tgagataaat ttaatcttgt agtaatcaga tcgtttgtaa
    62581 gtttcactgt attctaaaac ttggccagtt gattcgagtt tggtgatttt agtttgtagg
    62641 acagtaggga attgttcatc gactccgagg actgaagccg catgttctgg agttggaaag
    62701 actatttcgt tgatttcttc aaagtgttca tcattcatgt gaatgtggta gtctaacttg
    62761 aaacgattat agatagaact atagtattca aggtttggat aatttgcgtt gatatattgt
    62821 tctgggatgt aggatgtatg gtagatataa acgacaccgt ttgattcgcg gatacgttca
    62881 atcttgtagt agaattgatc gccacgtaga cccaattttt ccaagtaaac aagcttgttt
    62941 ccgcgttcaa ttgaaagaac agttacctta tcatctttag cattgaagag ttcaatatct
    63001 gaaaactcta caagcttgtg tttgcgtgca cgtgaaacga aggttccttt tccttgttgg
    63061 cggacaatat agccatcttt ggcaaggtcg tttaaggcgc gaacaactgt gatagagctg
    63121 acatcgtaca ttgaaatgag ttctgcttca gtgtaaaatt tatctccact gctaaactgc
    63181 ccagagatga ttttattttt taattcgtct tttatgtatt gatatttggg aattgccata
    63241 tttttacctc tattttcctt ctccatagaa aattttacca taaaagcgaa aaaaatagta
    63301 gtcttttgaa taaaaaatta gaataatagt ctgaaaaatt aagcgatata gggattgctc
    63361 ata
//
LOCUS       DAVMCN010000006        61694 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVMCN010000006 DAVMCN010000000
VERSION     DAVMCN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.006"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(336..761)
                     /locus_tag="VYP85_000489"
     CDS             complement(336..761)
                     /locus_tag="VYP85_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881042.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(890..1273)
                     /locus_tag="VYP85_000490"
     CDS             complement(890..1273)
                     /locus_tag="VYP85_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881043.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(1295..1501)
                     /locus_tag="VYP85_000491"
     CDS             complement(1295..1501)
                     /locus_tag="VYP85_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881044.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(1488..1661)
                     /locus_tag="VYP85_000492"
     CDS             complement(1488..1661)
                     /locus_tag="VYP85_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881045.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(2007..2963)
                     /gene="lytA"
                     /locus_tag="VYP85_000493"
     CDS             complement(2007..2963)
                     /gene="lytA"
                     /locus_tag="VYP85_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1881046.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(3339..4709)
                     /locus_tag="VYP85_000494"
     CDS             complement(3339..4709)
                     /locus_tag="VYP85_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1881047.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLSMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(5016..6182)
                     /gene="recA"
                     /locus_tag="VYP85_000495"
     CDS             complement(5016..6182)
                     /gene="recA"
                     /locus_tag="VYP85_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1881048.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(6237..7493)
                     /locus_tag="VYP85_000496"
     CDS             complement(6237..7493)
                     /locus_tag="VYP85_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1881049.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(7578..8594)
                     /locus_tag="VYP85_000497"
     CDS             complement(7578..8594)
                     /locus_tag="VYP85_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1881050.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(8602..9120)
                     /locus_tag="VYP85_000498"
     CDS             complement(8602..9120)
                     /locus_tag="VYP85_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881051.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(9110..9553)
                     /gene="tsaE"
                     /locus_tag="VYP85_000499"
     CDS             complement(9110..9553)
                     /gene="tsaE"
                     /locus_tag="VYP85_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1881052.1"
                     /translation="MYTKNEEELQALGESLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(9639..10259)
                     /locus_tag="VYP85_000500"
     CDS             complement(9639..10259)
                     /locus_tag="VYP85_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881053.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(10642..11505)
                     /locus_tag="VYP85_000501"
     CDS             complement(10642..11505)
                     /locus_tag="VYP85_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881054.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            11694..11864
                     /locus_tag="VYP85_000502"
     CDS             11694..11864
                     /locus_tag="VYP85_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881055.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            12314..14329
                     /locus_tag="VYP85_000503"
     CDS             12314..14329
                     /locus_tag="VYP85_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1881056.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTTGEGLLSYNLILLSISLFFTQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            14331..14963
                     /locus_tag="VYP85_000504"
     CDS             14331..14963
                     /locus_tag="VYP85_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881057.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(15891..16304)
                     /gene="ndk"
                     /locus_tag="VYP85_000505"
     CDS             complement(15891..16304)
                     /gene="ndk"
                     /locus_tag="VYP85_000505"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1881058.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(16415..20092)
                     /gene="rpoC"
                     /locus_tag="VYP85_000506"
     CDS             complement(16415..20092)
                     /gene="rpoC"
                     /locus_tag="VYP85_000506"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1881059.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(20125..23736)
                     /gene="rpoB"
                     /locus_tag="VYP85_000507"
     CDS             complement(20125..23736)
                     /gene="rpoB"
                     /locus_tag="VYP85_000507"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1881060.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            24152..24222
                     /locus_tag="VYP85_000508"
     tRNA            24152..24222
                     /locus_tag="VYP85_000508"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24184..24186,aa:Cys,seq:gca)
     gene            complement(24420..25751)
                     /locus_tag="VYP85_000509"
     CDS             complement(24420..25751)
                     /locus_tag="VYP85_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1881061.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(26042..26866)
                     /gene="endA"
                     /locus_tag="VYP85_000510"
     CDS             complement(26042..26866)
                     /gene="endA"
                     /locus_tag="VYP85_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1881062.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(26905..27093)
                     /locus_tag="VYP85_000511"
     CDS             complement(26905..27093)
                     /locus_tag="VYP85_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1881063.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(27086..28369)
                     /gene="murA"
                     /locus_tag="VYP85_000512"
     CDS             complement(27086..28369)
                     /gene="murA"
                     /locus_tag="VYP85_000512"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1881064.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(28393..28623)
                     /locus_tag="VYP85_000513"
     CDS             complement(28393..28623)
                     /locus_tag="VYP85_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1881065.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(28681..29718)
                     /locus_tag="VYP85_000514"
     CDS             complement(28681..29718)
                     /locus_tag="VYP85_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1881066.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(29702..30190)
                     /gene="coaD"
                     /locus_tag="VYP85_000515"
     CDS             complement(29702..30190)
                     /gene="coaD"
                     /locus_tag="VYP85_000515"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1881067.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(30180..30719)
                     /gene="rsmD"
                     /locus_tag="VYP85_000516"
     CDS             complement(30180..30719)
                     /gene="rsmD"
                     /locus_tag="VYP85_000516"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1881068.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLIFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(30784..31776)
                     /locus_tag="VYP85_000517"
     CDS             complement(30784..31776)
                     /locus_tag="VYP85_000517"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1881069.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(31888..32571)
                     /locus_tag="VYP85_000518"
     CDS             complement(31888..32571)
                     /locus_tag="VYP85_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1881070.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(32627..33367)
                     /locus_tag="VYP85_000519"
     CDS             complement(32627..33367)
                     /locus_tag="VYP85_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1881071.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            33401..33679
                     /locus_tag="VYP85_000520"
     CDS             33401..33679
                     /locus_tag="VYP85_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1881072.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            33757..34683
                     /gene="yidC"
                     /locus_tag="VYP85_000521"
     CDS             33757..34683
                     /gene="yidC"
                     /locus_tag="VYP85_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1881073.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(34758..35552)
                     /gene="pflA"
                     /locus_tag="VYP85_000522"
     CDS             complement(34758..35552)
                     /gene="pflA"
                     /locus_tag="VYP85_000522"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1881074.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(35678..36928)
                     /locus_tag="VYP85_000523"
     CDS             complement(35678..36928)
                     /locus_tag="VYP85_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1881075.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYHPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(36995..37822)
                     /gene="purR"
                     /locus_tag="VYP85_000524"
     CDS             complement(36995..37822)
                     /gene="purR"
                     /locus_tag="VYP85_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1881076.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(38089..39030)
                     /locus_tag="VYP85_000525"
     CDS             complement(38089..39030)
                     /locus_tag="VYP85_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1881077.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(39020..40276)
                     /locus_tag="VYP85_000526"
     CDS             complement(39020..40276)
                     /locus_tag="VYP85_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1881078.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(40278..40940)
                     /locus_tag="VYP85_000527"
     CDS             complement(40278..40940)
                     /locus_tag="VYP85_000527"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1881079.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(40903..41559)
                     /locus_tag="VYP85_000528"
     CDS             complement(40903..41559)
                     /locus_tag="VYP85_000528"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1881080.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(41570..42448)
                     /gene="rsgA"
                     /locus_tag="VYP85_000529"
     CDS             complement(41570..42448)
                     /gene="rsgA"
                     /locus_tag="VYP85_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1881081.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(42450..43322)
                     /gene="rsmA"
                     /locus_tag="VYP85_000530"
     CDS             complement(42450..43322)
                     /gene="rsmA"
                     /locus_tag="VYP85_000530"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1881082.1"
                     /translation="MRIADYRVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(43453..43761)
                     /locus_tag="VYP85_000531"
     CDS             complement(43453..43761)
                     /locus_tag="VYP85_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881083.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(43754..44395)
                     /locus_tag="VYP85_000532"
     CDS             complement(43754..44395)
                     /locus_tag="VYP85_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881084.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(44397..46427)
                     /locus_tag="VYP85_000533"
     CDS             complement(44397..46427)
                     /locus_tag="VYP85_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1881085.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(46504..46800)
                     /locus_tag="VYP85_000534"
     CDS             complement(46504..46800)
                     /locus_tag="VYP85_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1881086.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(47120..48031)
                     /locus_tag="VYP85_000535"
     CDS             complement(47120..48031)
                     /locus_tag="VYP85_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881087.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(48103..48663)
                     /gene="rnmV"
                     /locus_tag="VYP85_000536"
     CDS             complement(48103..48663)
                     /gene="rnmV"
                     /locus_tag="VYP85_000536"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1881088.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(48663..49436)
                     /locus_tag="VYP85_000537"
     CDS             complement(48663..49436)
                     /locus_tag="VYP85_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1881089.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELLLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(49741..50406)
                     /locus_tag="VYP85_000538"
     CDS             complement(49741..50406)
                     /locus_tag="VYP85_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1881090.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            complement(50669..50803)
                     /gene="rpmH"
                     /locus_tag="VYP85_000539"
     CDS             complement(50669..50803)
                     /gene="rpmH"
                     /locus_tag="VYP85_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1881091.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(50948..52162)
                     /locus_tag="VYP85_000540"
     CDS             complement(50948..52162)
                     /locus_tag="VYP85_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1881092.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKKLLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(52318..52611)
                     /locus_tag="VYP85_000541"
     CDS             complement(52318..52611)
                     /locus_tag="VYP85_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881093.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            52773..53225
                     /locus_tag="VYP85_000542"
     CDS             52773..53225
                     /locus_tag="VYP85_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1881094.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(53260..54648)
                     /locus_tag="VYP85_000543"
     CDS             complement(53260..54648)
                     /locus_tag="VYP85_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1881095.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            54714..55676
                     /locus_tag="VYP85_000544"
     CDS             54714..55676
                     /locus_tag="VYP85_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1881096.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(55705..55908)
                     /locus_tag="VYP85_000545"
     CDS             complement(55705..55908)
                     /locus_tag="VYP85_000545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881097.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSNHTYGKAT"
     gene            complement(55972..56982)
                     /gene="ccpA"
                     /locus_tag="VYP85_000546"
     CDS             complement(55972..56982)
                     /gene="ccpA"
                     /locus_tag="VYP85_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1881098.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(57407..58006)
                     /locus_tag="VYP85_000547"
     CDS             complement(57407..58006)
                     /locus_tag="VYP85_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881099.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(58008..59105)
                     /locus_tag="VYP85_000548"
     CDS             complement(58008..59105)
                     /locus_tag="VYP85_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1881100.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(59105..59842)
                     /locus_tag="VYP85_000549"
     CDS             complement(59105..59842)
                     /locus_tag="VYP85_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881101.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(59844..60728)
                     /locus_tag="VYP85_000550"
     CDS             complement(59844..60728)
                     /locus_tag="VYP85_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881102.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(60715..60909)
                     /locus_tag="VYP85_000551"
     CDS             complement(60715..60909)
                     /locus_tag="VYP85_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881103.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(60906..61112)
                     /locus_tag="VYP85_000552"
     CDS             complement(60906..61112)
                     /locus_tag="VYP85_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881104.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        18017 a        13922 c        11400 g        18355 t
ORIGIN      
        1 ataaccaaaa actactcgct atcccctctc acattaccct acatatcgtt tgacatgcga
       61 ctgatagttc aggaaaactt caaggagaac ttttctctca tccactatgc aggacttact
      121 atttcacttc tactcctata ggctcaattt gacacttttc tttttcgaat tgctcatatg
      181 cctcctgaat agtgagttcg atttatccaa atttattttt gtctattttg atgaatactt
      241 ccacgaagat agtctgaaaa tgaatttgca ccaattttcc ttctcttttt aagcatatta
      301 ttccagatat gattgccctc ttgttcagta ataaattacg ctttaaacgc ttcaatcagt
      361 atatctcctg ttgtcatatg ttctaaagaa aattcttcta catatgattt aacatctctt
      421 aggttattac ttcctaatat cccattatgc tttttcgcta aggaaataga agccgcttct
      481 cccttaccaa taatcttgtt attatcatga tttcttgtta aatctctata taatgcgtat
      541 tcttcagttc caatgtctat gctcacaatc tcagctgaac ccttagctac caactgatct
      601 atcctagatt ttaaatgggg aattgtaggt atattgattt catcatacac ctcttgtgga
      661 ataacaattt tacccgaata gagcttttct aaaagatgtt cagtgccaac ccataaaaat
      721 actgaaatac aatctgcatc aataaataca cgactagtca aacgacaact cccccctctt
      781 catctagccc atatacaata tcatatctga aagcatctag taacagttcc tcatacttcc
      841 cttgcgaaat tctgttattt tctaaaagtt gttcagttga attaatatat tatcctaata
      901 ccatttcctt tttactttct gacaaaggac gatataaact tgtatcatag cctaatcttg
      961 aagctgtctc tataacacta atatccatat ttttaatttc ttctgcatca aggtatccat
     1021 cattcctcaa tctatataac atagctttat gactgatacc ataaaactga cccaatttta
     1081 taatatcttc tacttcaaga tgagttctat tggcattttc tctgatttcc tcaaccatcc
     1141 tatacagtga agatgggaaa attaaaaaat aagaagcaag ctgatccgct tttctttcag
     1201 tttcatctcc ttcaccaatc aagataagac tgactgaact cttcttcacc tcatcataat
     1261 aaagatgata cagttcatgt gctaaagaaa atctttacct tcctaatgac atgtctgaat
     1321 tgactgcaat gagactgaac tgagttcctt tataacagac tccgctaata ttctttccga
     1381 gtccataaaa taccagcgtc aaattttcta tcttttgtac caatttaaaa atatctatcg
     1441 gcgcttcacc atcagctccc aacttttttc taagatttga agctttatta cttaaatcca
     1501 ttcgtgatat tcctttcacc tttttccatt ttggcaatca tgctttgatt caaagacaaa
     1561 tataaagaca aatattcagc aatcttatct tgagtaagat ttgaagatat tctaagttct
     1621 tttattcttt ttccaacatc acatacattt atcatattca tacacctctc ataaaaagaa
     1681 tagcacactt ttgtcataat tttttaaata aaaaaattat gacaaaacaa ggaagcaatt
     1741 tattgatgct gcttaaaaat ctaaaattga tgagttccta tcaaaaatcg tatcttcaac
     1801 ctcaaaacag tacttaaagc tatccgactc ggtttacatt gtcaaattta gattttattt
     1861 gagcataact ttctagtttg ctttctgatt tttgtttaat atagtagcaa acattgaagg
     1921 aaatatctcc acaaaaaaac gcatactatt aagctttttc aagacctaat aatatgcgct
     1981 gttctgattt gaaagacatt ccattattat tttactgtaa tcaagccatc tggctctact
     2041 gtgaattctg gcttgtctgc cagtgttccg tctggtttga ggtagtacca gcctgttccg
     2101 tccgctgact ggataaaggc atttgatacc atggcgcctt ctttagcgtc taagtagtac
     2161 caagtgtcct tgtacttgac ccagcctgtc ttcatggcac cttcttcgtt gaaatagtac
     2221 cacttatcag cgattttctt ccagcctgta gccatttcgc ctgagttgtc gaaccagtac
     2281 cagttgccgt ctgtgtgctt cctccagcgg tctgcaagca tatagcctga actgtcaaag
     2341 tagtaccaag tgccattgat tttctcaaac ttgtcttttg gataagagcc gtctgaatgt
     2401 acgtaccagt agccagtgtc attcttctgc cagcctgttt caatcgtcaa gccgttctca
     2461 atatcatact taaactgctc acggctaatg ccccattttg ccaagtaagg gtatggatcc
     2521 acatggtctg agtggttgtt tggttggtta ttcgtgcaat actcgtgcgt tttaattcca
     2581 gctaaactcc ctgtatcaag cgttttcggc aaacctgctt catctgctag attgcgtaag
     2641 agttcgatat aaaggcggta gtccgtcatg aactcttctt tagttgaatg gctttcaatc
     2701 agttcaaccg ctgcataggt ctcagcattc caaccgcccc caacgtccca ggcaccatta
     2761 tcaacaggtc ctacctgcat gatgcaaccg ttcccaacaa tgtgcgagaa aaaacctaat
     2821 tctgggtctt tccgccagtg ataatccgct tcattctgta cggttgaatg cggattccca
     2881 gttgagtgtg cgtgtacttg cctatatggt tgcacgccga cttgaggcaa atctgttctt
     2941 aatttactca cattaatttc catattctac tccttatcaa ttaaaacaac tcatttttta
     3001 caatccagaa ccagaaactc ctttatttct accttacaaa gaagacaatc ttagtcacga
     3061 ttaggcttgt agatagaacc tcaaaacgca ctattttgac actgtaaata ggactgacaa
     3121 ggtctgcatt ctatctacaa taacacccca gactaaaaag cttttcaaaa gtatattttt
     3181 acagtctcta tatgtccttt tcataaatac tatactttat tatatcatat aaaagaagtc
     3241 aaaagtctgt taaactattt tcaacaccaa actaaagaag agaacacaag ttttttcgat
     3301 gttcactaga ggaaatggat tttattcagt aaatccaact aggattgcac tttggttgcc
     3361 aaaattgcct ttccttcttt tatcaaggga tgacggaata gtgagaagta cagttgaact
     3421 gtcatggcaa cccagataag aggttcacaa aggataacac ccttatatcc tgcccaagga
     3481 ataatcaaaa ccacaaaaac gatttttccg attagttcaa taaagctaga aactagagga
     3541 aggatcttct gccccaagcc ctgcaagcaa ttgcgataaa tcaacaagag gctcaaaatg
     3601 ggataaaagg ctgaactgat ttgcagatag agacttccat tttctatcaa gtaaccatct
     3661 gtcgaactag ccaagaagga aaccaaggct ggactggcaa aaaagaggaa aatacaaaca
     3721 aaaactgccc aggatatact taaacgactg ccgattcgaa gaccttgaac aatgcggtca
     3781 ggtcgcttag ctcctagatt ctgagaagca aaggtcgtca ttgatgcaga aatagcggtc
     3841 ataggaagaa gggcaaaggt cataatgcgt cgagctgccg tctgggcact aataatcact
     3901 gcaccaaatg tattaacaga aaactgtaaa atcacactgc cgatagatac aattgaactc
     3961 atcaagccca tagacaaacc ttgctccaag agatccgcgt acaagctttt gtcccatttg
     4021 aaatgtttaa actgtggcaa gagttctggc acacttttac gaatataata aaagcagaga
     4081 accgctgata aaccttgcga aataatggta gcaagtcctg cggattgaac tcccagatgc
     4141 aattgcgtaa taaaatagag atccagaacc acattaacca aggcagagaa aatcagaaat
     4201 cccagggctg ctagactgtc accaatagac cgcaacaagc ctgcaaaaag attataagca
     4261 aagctgacac ctacacaggt cacaatcata gaaatatatt gataagattg aggaagaatt
     4321 tctgcaggag tatctaagta ttgcaagaga ggatacaagc caagaaagcc cagcaacata
     4381 actagaatgc tcaaaagagc acctaaaatc caagtagctg ctactgcttc cttgatttta
     4441 gtgaaattcc gagccccata ataacgagca atgacaatcc ccatgccatt gccaacacca
     4501 agtgtaaaac ctacaatcag gtcaaaaatc gctgtcgtcg ctcctactgc agccaaggat
     4561 tcttgaccaa gaaatcgtcc aacaatcaag acatcagcag tgttatagag ctgttgaaaa
     4621 atatttgata gcaaaattgg aaaggtgaag cttaagagcg agggaagaat cggaccatgt
     4681 atcaggtcca ctgttcgttt tttattcata aagctattat atcagctttc cagaggagcg
     4741 acaagaaaca gcaaacttat atatagcgga atgaaataag gaaagtcaaa tcgattttta
     4801 acaatgtttt agaagtagat atgtactatt ctagtttcga tctattatag ttggttgagt
     4861 ttggaatagt acgctgtagc tgctaaaaca tttctagaaa ttaatttgac tttcctaata
     4921 gagttgttca tatcttattt caagctacta tatataatct aaaaacttga atcaaaaatc
     4981 gaaaaagtag cggatttctc cactgcttta acagcttatt cttcaatttc gatttcaagt
     5041 tcatcgccta agtcaagcgt aacttcttca ttcactgctt cttctttctt tggctcatct
     5101 tttttgtttt cagtatcttg ttctgaaact tcttctccat caatcaagcc aaatttagaa
     5161 cggacttgct tatcaatttc atcaaagatt tctgggtgct ctgccaagta tttcttagca
     5221 ttctcagaac cttgcccaat tttttcatct ttgtaagaat accaagcccc tgcttttttg
     5281 ataatatcca aatcgcttgc aatcttcaaa agctcaccag tcttagaaat tccttctccg
     5341 tacataattt caactacggc ttccttaaac ggtggagcta ccttattttt tacaacctta
     5401 atcttagttt ctttaccgac attggtttct ttttggtcac cagttccctt aatttgtgta
     5461 ttaccacgaa catccaagcg gactgaagca tagaatttca aagcacgtcc acccggtgtt
     5521 gtttctggat ttccaaacat cactccaact ttttcacgca attggttgat aaaaatggca
     5581 attgttttgg ttttattgat agaggcgcca agtttacgca tggcctggct catcatacga
     5641 gcctgcaaac caacatggct atctccgata tctccatcaa tttccgcacg aggaacaagg
     5701 gcagcaactg agtcgactac gacaagatca actgcacctg agtcaatcaa ttttcccgca
     5761 atctcaagac cttgctctcc tgagtctggt tgagacaaga gcaattcgtc aatattgaca
     5821 ccaagggccg cagcataagc tggatcaagg gcatgttccg catcgataaa ggcagcaatc
     5881 ccaccttctt tttgcgcttg tgcaactgca tgaagggcaa ccgttgtctt accagatgac
     5941 tctgggccat agatttcgat gatacgtccc ttaggataac cacctgagcc aagggcaatg
     6001 tcaagagcta aagaacctga gctcatcact tgcacctttt gctctgcacg ttcacccaaa
     6061 cgcatgattg atcctttacc aaagtctttc tcaatcaatt taagagcatc attcaaggcc
     6121 ttttcacgtt ctgccccaaa tttttttgaa atttcttcta atttttttgg ttttttcgcc
     6181 attctattct cctacattct aatgatcctc agacctatct actattatat caaaagttag
     6241 tcacttaata aagccttgcg aactaggtta aaggcatgca taaccgcaat gtgacgtaca
     6301 tctgctcggc ttctgcctcc aatattaacc ttgataacct cagttccttg atcttgcgcc
     6361 aagcctatga agactgtccc aactgggttt ccttctaggc tatctggtcc tgccactcca
     6421 gtcaaactaa ttccaaaatc agactgggtc ttgcttcgtg cctgctcagc catcttctga
     6481 gctgtaaatt cagacaccac accatgttct tccaaattct tggcaggaat atccaacatc
     6541 cttgattttt cctccaagct ataggtcaca aaaccgccct taaatatact tgaaactcca
     6601 gaaaaattcg ccacggtagc ttggaaaaga cctgccgtca aactctctgc agccgcgatg
     6661 gttttccctt gccttttcag ttcttctacc acaatgctgg ctaaactagt ttcttcccca
     6721 taaccatagc aaaagtctcg taaagaaatt ccttcgaaag tctggcagtc caagatttga
     6781 ttttccaaga tatccagcgc ttgattcgcc tcttcttgac tgctagcctt tgttgacaga
     6841 cgtagagtga cttctcctgt cttggcataa ggggccaagg taggatcgat ctgattatca
     6901 attaaatcag ccaaaatcgt aaccaactgg ctctcgccaa tcccaaagaa acgaagaact
     6961 cgggaataca gcttgctccc tgtcatcaac ttgggtagaa gttggtttaa gaccatgggt
     7021 ttcaattcac ttggcggacc tggaaggacg acataggtca ctccgtctac ttctaatttt
     7081 cctccaacag ccagtcctgt ttcgtttggc agtggaatcg ctccttctac aatttgagct
     7141 tgtctttcgt tattcggtgt tcgggcatag tctggtcgca gggtaaaaaa gatatccaac
     7201 ttctcctgag cctgaggatc aaagactaat gctttcccta aaaatttagc tagggtttgt
     7261 ttggttaggt cgtcctcagt tggccccaaa ccgcctgtca aaatcaccag actgctacgt
     7321 tgactggcaa tctcaagcaa agacaagaga cgaacttcat tgtctcctac agccgtctga
     7381 aaatatacat ctaccccaat ctcagctagt ttttccgaca aaaactgggc attggtgttg
     7441 acaatctgcc ctgtcaaaat ctctgttcca acagcaatga tttctgcttt catgtttcct
     7501 cctacctatc tattcgtatt tttttgaaaa aatcgcagga attttcctac gattgatttt
     7561 tttatttgta tcaaaagtta attatcttca tcaccaacag gtgctctgcc aaataaatct
     7621 tcaaataaaa ccgcattggt ttcaagctga gtaacttctt cttgtcccaa agaacgtcgg
     7681 agtagatttt gcatttccaa catatgtgct ctcgaaacaa tctggtaaga aacaccttga
     7741 agtatctctc cttcaccctg caactgctga gtttcaatgg ttttaaatga atctttatag
     7801 cctagcaagt tagggatact ttttgcagac aaatcaatat tggtctgcat attgtcactc
     7861 aaagctttta gaatctcttg ataatgacca atgctattta aactgagagc tttttccatg
     7921 actttttgaa taacttcacg ttgacgtttt tgacgaccat aatccccctc aggatcttgg
     7981 taacgcattc gtgcatagac tagggcttct tctcccccaa tatgttgctc cccaacaccg
     8041 atagaaatag tattaaattc ttcttggtca ctgatagaaa ttgggaaacc taggatatta
     8101 ttgactgtaa tacctcctac tgcatccact agtttttgca atcctctcat attgaccatc
     8161 acatagcgat caatatggat attcatcatt ttttgaatgg tttctatagc aagctctgct
     8221 ccaccatctg catatgctga gttcagtttc gcttcatgag cctgaccatt ccctgattca
     8281 atgcgcgtca gaatatcccg ctctaaactc atcattgttg tttttttcgt tttaggattc
     8341 actgtcatca agatcatgct atcacttcta ccgacccaag tttcagttcg ttcaacattt
     8401 ccggtgtcca ctcccattaa cagaatggtt agaggttcag tcgcttcaat aaccttggtt
     8461 tcttcgccga tttttttata ggttttagct aaggtttctg tcccttgttg ataaatagta
     8521 taagcaaaaa cacctactcc tactacagtt acagaaagta aagctagcac cattccaata
     8581 atttttttaa ccatatttct actaacctat cagtttaccc atcaagtaaa catcgataaa
     8641 tttcccttct tctatatatg ccccacgctc ttggctacct tcaatgacaa agccatgctt
     8701 ttgataaaga tggactgctg cttgattacg agtttggaca gtcagttgga gacgacgcag
     8761 aatgccactt gcttgtgccc actctatcgc ttcttctagc aacaaacttc ccaagccatt
     8821 attccaatat ctttttccaa tcacaatgaa gagatctcca atatgacgga ctctcttacg
     8881 ctggtcagct gtaatattta caataccagc aattttgcca tttaagaatg caagtaaggt
     8941 tatctgattg tccgaactag cttgcttgtt gaggaatatt tccatctcct cactagtcaa
     9001 gagaatacca tctccgtcta ggctggtaaa gtctgtctcc aaactcacac gatttaaaaa
     9061 ggccactaat tcagctgcat ctttgggctc tgcttcccta atgagcaatt catactccat
     9121 attgaagctc ctctaacaat ttctcagcac gcaaaccctt tgcctgaaaa tttaaacggc
     9181 gtccatctgc ttcttttaga atttccaatt ctaaataagc atctggcaag gcatctccta
     9241 agagatttcc ccactcaata acagtcacgc caccaccaaa gataaactca tccaagtcga
     9301 tagaatcagc atctccttca atacgataaa catctaggtg ataaagtgga agtcgacctt
     9361 catactctct cacgatagta taggtgggac ttttaatcat ttgagaaatc tgtaatcctt
     9421 ttgcaagtcc tttagtaaag gtcgttttac ctgcacccag ttctccagtt aagattaaaa
     9481 catcattctt tgctaataga tggcccaaac tctcccctaa ggcttgcaac tcttcttcat
     9541 tttttgtgta catactctta ttataccaaa aacttttctt ttgtgtctat tttcctacta
     9601 aacttatcat cataacatcc ataaaaaaca ggctttctct aaaagaaaat gagcgtaaca
     9661 atgaccaata caagatctcg gaaaatatga ccataaaagg aaacttcctt cttaaccgaa
     9721 tttgggacaa gataggctgc aaaaaacaag cccagtccaa tataaatcag aagtgagaca
     9781 atggtcattg gatttcttaa gaaaagaagt gttgctaaaa tagtcaccaa cactgtcttt
     9841 tttctgtcta gcatagcaag aaaatcgcgc acgtattttt tcaagggtaa aaaaatcagc
     9901 aaatctagcc caaataggaa aaagaaggat ggcaataaaa agtcaactaa ttcttgctgc
     9961 agcgtatttt tgatgaacaa gttatctgac aaaacaagaa cagctcctaa caaattaatt
    10021 aagagtaaca tactgtaaaa aagcttcacc gacttcttac tggctaggac actatggact
    10081 tcttgcttac gggtataaag ataatttact ccagcacaga ttcctgaaac gaaaaccatg
    10141 cttccgatga aaaaagctgt actttgttta aaggacaaga tgcattcctt ccataggaaa
    10201 cagctactca aactgatttg aattaaagct aacaaaaata agattctcat tgatttcatc
    10261 ttctctctcc cttcctacca atcattatac taggagaaaa gagagaactg tttctaatct
    10321 tctcaaatgt ctctttaaga cgctaaacaa acactagaga ctaatactca atgaaaatca
    10381 aagatcaaac taggtagcta gccacaggtt gctcaaaaca gtgttttgag attgcagata
    10441 gagctgacgt gatttgaaga gattttcgaa gaatatagat ttgaaatcat gaaaatccgt
    10501 caaacgggtg gttgttttgt ctcgcacctc acggagcgag acggactcag agtcacataa
    10561 ttataaggct gatagtatta atctaactat cagccttaca ggttatttaa cgtttcagaa
    10621 aaactataat gtcaagatta actaaacagt atctagttcc ttcaaataat tttctatctt
    10681 catcagcatt aaaggattgt tataaatctt gcatagctct cttgcttcta tataataatt
    10741 tttgacttgt tctctgtcta gaaatttggc tccagcattt cctacaagaa taagtagagg
    10801 agccaattgg tagcttgtct gtctttgttt acagagttca atcgtttcaa gagcttcttg
    10861 gatggcttca ttatattttt cctttgatac taggtagtga gcgtagttgt aacgaactct
    10921 gatgtagcca aataaaaact cttgatggtc caaatttttt gtctgataca actctattaa
    10981 atgagagtag tttgcctcat attcttgttc acgacccact aaggaataga aattagatag
    11041 agtattcaac gcctttaaat aaatcagagt atttgaagag acttttaata atatattttc
    11101 caatgaagaa attgcctcac acttactgtc atattgatag aagtcaataa tagctttaat
    11161 ccattcaagg taagttcggt cttctagtgt tagaaaagta cttcgttcaa tctctattct
    11221 ataaatatat tccaaatcgt cataatttct atcgtctaat agtcgagcag acaattgctt
    11281 gaaattagag aggttagatt taatttcaat ttgttcatta aaaaaataat ctaatggtac
    11341 ttcaagtcgt tgagagagtt tgaacaaaag gtctgcggag ggaatgaaat gccctctctc
    11401 aattttacta atctggcttt gttcacaaat tccttctgca agagtttgtt gggagagtct
    11461 caactctttt cttttcaatc tgaatttctc tgcgagtgta ttcattaaag ataataaacc
    11521 ttcctatttg cttaattgca ttataaaatt tttagttcaa aatagcaagt taaaggaata
    11581 aataattctt tatggtaata aactaaaaaa agtcaaaaat tacataaaaa tgcttgaccg
    11641 aataatatat atatattaaa ataaaaacaa ggaaaaagaa aagggtttca cgaatgaaga
    11701 aaaatcgtgg aattcaaaaa ttagctatat tagtattact aggtgttttt atgtttagta
    11761 acacaattcc ttaccaacag tttattcaga agaatagaca attggagatt cgagtgcaat
    11821 cacaaaagaa gtccaatggt cttgatgttg ggaaggctga ttgatttcgt attactttaa
    11881 aattcaacta tttagagaaa ggtattctga tgagagcttg taacaatacc agatagatat
    11941 aagaatggag atgtttgata aaatgctttc atagctaacc aactgttgaa aattatgagt
    12001 tacaaaatct aaagtattta agattggttt ataaaattag gtctctgcct gtagaaagga
    12061 acgtgcagtt agaaaggagg aaaaaatagg atactataat tcagactgag atttctaatt
    12121 aaaatatgta gttgcatttc gctcattttc ataatatttc attcagagga gtaataatat
    12181 gttaaaattt agatttgatg cgggatggta aagaataatt gaagaagatt cttttatcaa
    12241 tagtttagta agcttgttag tttatagagg gcaggggtat ttctgccctc tgttttagaa
    12301 taaggaatgc actatgaaaa aattatttat actcatatcc aacctgcttg ctagtttgtt
    12361 ctttgtttgg gtatttacca tttggactga tacatatgtc tcccattatt accccaacgt
    12421 tgttgtacgt gattcttccc ctgaaacaac ttttcagcat gttgctacac gcttggaaaa
    12481 actagcagaa gaaacagata gctttattgc gattcaacac caagatccta actcagaagg
    12541 tactacagtt ttttcttata cgacctttgg ggacggaaag ttgcctgatg ggcttcagga
    12601 aaaaaatcta gaagatgctc aaagtagtag tgttgaaaca aactattttg tattcgatgg
    12661 acacctagat attcacttgc taagggaaga gctaagtcaa cttggcttga ctaacatgca
    12721 cctgacaatt ccatctaaac tatctacgtt aatggctatc tttagtaacg gatttcagtt
    12781 aatcagtcta ttgattttca tcttaacctt tgtagcactg actttaatta gtcaaattag
    12841 ccaattacgg tcatcgggca ttcgcctcat ttcaggagag aaacggtggt ccattttcct
    12901 tagaccagtt ggtgaggatt tgaaagcgat agctgttggt ttcagtttag ctggcgtgct
    12961 cgccattctt atgcaaaaaa ttctgtcgct tccaacgcaa tccctaatga ccacaggaga
    13021 aggcttgctc agttataatc tcatcttgtt gtcgatctcc ctgtttttca ctcaactctt
    13081 cgcagttggg ataaaaaaga tacacctgat gcagattata aaagggcaag tgcctgtcag
    13141 aggaatcatt agtttgattt taatcggtca actattagcg attattattg taacgctggg
    13201 aatagggagt agcttaaagt attcccaagc ctggcaacag catcggattg gacaagaggt
    13261 ttggagtcag gaaaggcaac tgattaccct atcaatcagc cgtgaaggaa cgagtcctgg
    13321 ttttgatgaa caagctcaaa ggaaactcag aacttggtat caattgatgg atctggctgt
    13381 ttcagaacaa aaggctttct tatctagaca ccagttaatt gaccgtactt tgcaaaatgg
    13441 catggcttcc tccaaaaact tgataacctc tacagaatgg cacgattaca acccgaatgg
    13501 caatgtcctt atcgtcacac cgcaatactt ggagcgtcaa aacattcctg tagatacaac
    13561 tattgagcaa aagatgaatc accttgatgt aggggagttt gtcttattgc tgcctgaaca
    13621 cctccgttca gaggaagaac attataaatc tgtttttgaa gacgacttaa ccagtcgcat
    13681 gtctagtcaa gatgaacgac agcaaatgac tgctacggta ggttatttag aatcaggtca
    13741 ggatcgtttt gtgtataata cgacccctat ttcttaccag cagtttttga aagatccaat
    13801 catcattgtt ataacacccc aatcaactgg tccacagtcc attttgtttt ggatagacgc
    13861 agtacagaac tacgttctct ttaatcaatt gtctgatgcc caggagctta tccagagaca
    13921 aggcattgaa aattgggtct cagaaatgca aacaggttac cacaactaca tcacattatt
    13981 ggataatatc cagagggaac gttgggtaat gctagcagga gctgtgcttg ggattgcaac
    14041 ttcaatcttg ttgtttaaca ctatgaatag gctctacttt gaagaattta gacgtgccat
    14101 ttttatcaaa cgcattgcag gtctcaggtt cttagaaatc catcgcactt atctctttgc
    14161 tcaactgggt gtgtttttac tgggatttgt tgcgagtgta tttcttcagg tagagatagg
    14221 agttgctttc ttagtcttgt tactctttac tggtctatct cttttacagt tacatgtcca
    14281 aatgcagaaa gaaaacaaga tgtccattct tgttttgaag ggaggttaat atgattgaac
    14341 ttaaacaggt gagtaaatct tttggagaac gagagttatt ttcgaatctt tcaatgacat
    14401 ttgaggctgg aaaagtctat gccttaattg gttcaagtgg tagcggaaaa acaaccttga
    14461 tgaacatgat tgggaaatta gaaccttatg atgggacgat tttttaccga ggtaaagact
    14521 tggccaatta taaatcgagt gattttttcc gtcacgaatt gggctacctc ttccagaact
    14581 ttggcttaat tgaaaaccaa agtattgaag aaaaccttaa gctaggtctc attggtcaaa
    14641 agttgagtcg gtcggaacag cggttgaggc agaagcaggc tttagaacag gtcggcctgg
    14701 cttatcttga cctagataag cgcatctttg agttatcggg cggagaatcg caacgggttg
    14761 ccttggcaaa aattatctta aagaatccac cctttattct ggcagatgag ccaacagctt
    14821 caatagaccc agcaacctct cagttgatta tggagatttt gctatctctt cgagatgata
    14881 ataggctaat cattatcgca acacataatc cggcaatttg ggagatggct gatgaagtgt
    14941 tcacgatgga tcatctgaaa taaaaatcct tgtttttaat tgcacgatga gttactgaaa
    15001 tattatcatg aatcaagaat tggagttaat ttagaattgt actttattaa tattgaggta
    15061 actttttctt gataaaggaa gaaataatgg agaggaagtt agaatgaaaa aattcgacaa
    15121 ttatattatt gagaagcctt gcgattctaa ttcagataaa ctgcaaaaaa tcttaataat
    15181 tgaaagtttg gtagatgata ttttgcaatt ttctctcaga atcaataata gtgtaggaga
    15241 gattttcctc ctacaaccgt tttaaaagaa aactatcttt attccatgtt attttgagga
    15301 agatattgtg aaagtcaaag atgatgataa agttgagtgg aatttgttag aatttcaaaa
    15361 atttagagca tttttggctt agtaatctgt gttgaaggct caaaacctat ggtaaaaaag
    15421 tcgctttgaa aacgtattgc ctccaaagat ttagttaaat aatgatttaa cacaaaaaga
    15481 aattattgaa gttctggaaa gatgttgttt cagtattgag aaaaggtggg aaaaacttgc
    15541 gattttcaca gagaaaggaa gaaaaagtat agaaatatag tcaattgaaa caagaacagg
    15601 ataaaagaac cttttgtgcc atatttttct cctttcgctt tacaattggc ttgaacacct
    15661 ttattgtatc gcgtttggag tttttttggt ataaccttcg acgcgcaccc gcatagcggg
    15721 tgtttttttg tctcgcacct aacggagcga gacgaactaa tagtcactta atcaaaaaac
    15781 gcaccatatc aaaaactaaa aagtttgata tcatgcgtca tgtcttaaac taattgacta
    15841 tactttctat tcaaatgagc ttttaaccaa ttgattgagc caatccactc ttaaaaccaa
    15901 agagcaattt ctcgcttagc tgactcttct gaatctgaac catgtacaac attttggata
    15961 acctcatttt ctccagcagc ttttgcaaag tcacctcgaa tagtgcctgg taaagcttct
    16021 tctggacgag ttgcacccat catggtccgc caagtttcga ttactttggg accagaaatg
    16081 acacccacaa gaactggacc tgaagtcatg aattcacgaa tcggtaggta aaaactctga
    16141 ccaaccaagt cctgatagtg ctggtcaatc aactcttctg aaacctgtga acgaaactcc
    16201 aatttttcga ttgtaaatcc acgttgttcg atgcgcttta acacttcacc cactagccct
    16261 ctttttacac catctggttt gatgataaag aatgtttgtt ccatacccgt ctcctttgtc
    16321 agcttctttc ttttatttta ccacatttcg tggaaaaatg gagaaagttt tcagaagaga
    16381 gaatgagaga acccgagggt tctctcattc tctcttattc tactgtttct tccacagttt
    16441 caacggcagt atccacaact acttctgttg tttcttcatt tccttcttcc tctactggag
    16501 gattaaggta ttcttcttcg ttgacagcat gtggttcaag gttacggtaa cgggccatac
    16561 cagtaccagc tgggatgatc ttaccgatga taacattttc tttaagtcca aggagatggt
    16621 ctttcttacc acggatagct gcgtcagtaa ggacacgagt tgtttcttgg aaggaagctg
    16681 ctgacaagaa actgtttgtt tcaagtgagg ctttggtaat tcccataagg actgggcgac
    16741 ctgtcgctgg aactccacct gcgataagga catctttgtt ggcatctgta aagtcattga
    16801 tatccatgag ggtacccatg agaagatctg tatcacctgg atccatgaca cggactttac
    16861 ggatcatttg acgaaccatt acctcgatgt gtttgtcacc gatttctacc ccttggctac
    16921 ggtaaacttt ttgtacttca ccgagaaggt acgtttcaac tgacaagaca tcacgaactg
    16981 caaggagacg ttttggttgg atagaacctt ctgtcagagc agcaccacgc gctacttggc
    17041 ccccaacttc gacacgcata cgagctgtaa atggaacgac atattcacct tcgccagttt
    17101 cacccttaac aaagactttc ttggtacgag ttgatgcatc ttcttcgata gcagtaactt
    17161 gtcctttaac ctctgtgata accgcttccc ctttaggatt acgggcttca aagatttctt
    17221 ggacacgagg aagaccctga gtgatatcgg tatttgaggc aaccccacct gtgtggaagg
    17281 tacgcattgt aagctgtgta ccaggttccc cgatagattg ggcagcaatt gtaccaactg
    17341 cttcaccaac ttcaaccgca tcaccagtcg ccaagtttat accgtaacag tgacggcaga
    17401 caccgtgacg agtgttacat gtaaatacag aacggatagt cacttcttcc acaccagcat
    17461 tgacaatttc acgcgccttg tcttctgtaa tcaattcatt tggaccaata atcactgcac
    17521 cagtttctgg atgtttaaca gttttcttag tgtaacgacc gttgagacgc tcttcgagag
    17581 actcgatcat ctcttttcct tctgcgatag aacggatcaa gagaccacgg tcagttccac
    17641 agtcgtcctc acggatgata acgtcttggg caacgtcgac caaacgacga gtcaagtaac
    17701 ctgagtcggc tgtcttaagg gccgtatcgg tcataccttt acgagcaccg tgagttgaga
    17761 agaacatttc caataccgac aaaccttcgc ggaagtttga aaggattggc aattccatga
    17821 tacgtccatt cggagcagcc atcagaccac gcataccggc aagctgtgag aagtttgaga
    17881 tgttaccacg ggctccagag tccatcatca taacgattgg gttcttagga tcttggttgg
    17941 caatcaagcg tttctcaagt ttttcacggg cagcacgcca ttcagctgta acagcattgt
    18001 aacgctcgtc gtctgtgatc ataccacgac ggaattgttt ggtgatttgt tcgacacgtt
    18061 tgtgtgattc ttcaatgatt tcagtcttgt catcaacgac tgggatatcg gcaataccca
    18121 ctgtcaatcc tgcaagagtt gagtggtggt aaccgaggtt cttcatgcgg tcaagtaggg
    18181 cagaagtttc tgtcgtacgg aaacgtttga agatttcagc gatgatattt ccaaggtttt
    18241 tcttcttgaa tggagggttg agctcaagat tgctgatagc ttccttgata tctccaccaa
    18301 gtggcaagaa gtatttagct ggaacacctt ctgtcaagtt ggcattgttt ggttcttgca
    18361 agtatggtag cccctctggc atgatatcgt tgaagagaat tttaccaact gttgtaagca
    18421 agaccttatg tctttgctct tctgtccaag gcttgttgag gctgtctgtt gcgataccaa
    18481 cacgtgagtg gaggtgaaca taaccattgc ggtaagccat aaccgcttcg tcacggtctt
    18541 tgaagaccat tccttcacct tcgcgaccag cttcttccat ggtcaagtag tagttaccca
    18601 aaaccatgtc ctgagatgga gtaactaccg gtttcccatc tttcgggttc aagatgtgct
    18661 cagcagctag catgaggata cgagcttctg cttgtgcttc ttctgaaagt ggtacgtgga
    18721 tggccatttg gtccccgtca aagtcagcat tgtaggcttc acagacaagt gggtgcaagc
    18781 gaagagcctt accatcaatt aagactggct cgaaggcttg gatacccaaa cggtgaaggg
    18841 tcggtgcgcg gttcaaaagc actgggtgtt ctttaatcac ttcttcaagg atatcccaga
    18901 tacgctcatc tccgcgttcc accaagcgtt tagctgcttt gacgttttgc acgatatcac
    18961 gggcaacgat ttcacgcatg acaaatggtt taaagagttc aatcgccatt tcacgtggca
    19021 caccacattg gtacatctta agagttggac caacggcgat aacggaacgt cctgagaagt
    19081 caacacgttt accgagcaag ttttgacgga agcgtccttg tttaccttta agcatgtggc
    19141 tcaatgattt caatggacgg ctacctggtc ctgtgattgg acgaccacga cgaccattgt
    19201 caatcaaagc gtcaactgct tcttgaagca tacgcttctc attttgaacg atgatacctg
    19261 gtgcatttaa ctcaagcaaa cgagccaaac ggttgttacg gttgataaca cggcggtaaa
    19321 ggtcattcaa gtcagatgag gcaaaacggc caccatccaa ctgcaacatt ggacgaagat
    19381 ctggtgggat aaccggaagg atgttaagaa tcatccattc aggtttgttt ccagacttgt
    19441 aaaaggcatc caaaacatcc aaacgacgga tggctttgac acgcttttgt ccagtagctg
    19501 ttttcaattc ttctttgagt tcagcaattt ctttttcaag atctacttgc ttcaaaaggt
    19561 cttggatggc ttccgcaccc atcttggcaa caaatgaacc ataaccatat tcacgcaagc
    19621 gctctcggta ttcgcgctct gtcatgatag acttgtgctc aagtggtgta tccttaggat
    19681 caatcaccac ataagccgca aagtagataa cttcctcgag ggcacgaggg ctcatatcaa
    19741 gggtcaagcc catacggctt ggaatcccct tgaagtacca gatgtgagat acaggagctt
    19801 tcaattcgat atgtcccata cgctcacgac gaactttcgt acgcgttact tcaaccccac
    19861 agcggtcaca aacaattcct ctgtaacgaa tgcgtttgta cttaccacaa gcacattccc
    19921 agtcttttgt aggaccaaag atcacttcat caaagagtcc ttcacgttct ggtttcaagg
    19981 tacgataatt gattgtttca ggttttttga cttctccata agaccatgaa cggactttac
    20041 ttggagaagc tagggtgatt tgcatacttt taaaacgatt tacatcaacc actatttctt
    20101 ccctttctat tctaagtgaa ctgcttattc ttgttcagca gcttcttctg ttgcttccgc
    20161 ttttgttgct ttctcagctt cttcagcttc aaaggctgct ttagcctctt gggctgcttt
    20221 ttcgcgggct ttttcaaggt catctacgtg gatgacatct tcgtccattc cttcatccaa
    20281 gtcgcgaagt tccacttctt ggtcatcttc gtctaggaca cgcatgtcaa gaccaagaga
    20341 ttgcaattct ttgacaagaa ctcggaagga ttctggaaca cctggttttg gaattggttt
    20401 gccttttgta atagcttcat aggctttcaa acgtccgttg atatcgtccg acttgtaagt
    20461 caagatttct tgaaggacat ttgacgcacc gtaggcttca agagcccaaa cctccatctc
    20521 accgaaacgt tgtccaccaa actgagcctt acctccgagt ggttgttggg taacagttga
    20581 gtatggtccg actgaacgcg cgtgcaattt atcatcaacc atgtggtgga gtttgatcat
    20641 gtacatgact ccgacagaaa cacggttatc aaacggttca ccagtacgtc catcgtaaag
    20701 gatcgttttg gcatcgctat ccatacctgc ttctttaaca gttgaccaaa gatcttcaga
    20761 acttgctcca tcaaagactg gtgtagcgat gtgaatacca agagtacgag ctgccatacc
    20821 aaggtgaagc tccataacct gaccgatatt catacgtgat ggtaccccaa gtgggttcaa
    20881 catgatgtcg actggagttc cgtctggaag gtaaggcatg tcttctacag gaacgatacg
    20941 agagacaacc cctttgtttc cgtgacgtcc ggccatttta tctccgacct taatcttacg
    21001 tttttgagcg atgtaaacac gaaccaacat gttaacacct gattgcaact catctccatt
    21061 tacacgtgta aagatcttaa catcacgaac gacaccatcg gcaccgtgtg gtacacgaag
    21121 agaagtatca cgcacttcac gagacttgtc tccaaagata gcgtgcaaga gacgttcttc
    21181 agctgaaaga tctttctcac ccttaggtgt tactttacct acaagaatat caccttcttt
    21241 aacctcagca ccaatacgga taatccccat ttcgtcaagg tctttgaggg catcttcacc
    21301 aacgtttgga atttcgcgag tgatttcttc aggcccaagc tttgtatcgc gcgtttctga
    21361 ttcgtattct tcaaggtgaa cagatgtgta gacatcgtcc ttcaccaagc gttcgctcat
    21421 gataacggca tcctcgaagt tgtaaccttc ccaagtcatg taggcaacga ttgggttttg
    21481 tccaagcgcc atttctccat tttccataga aggtccgtca gcgatgaaat cgcctttttc
    21541 aacgacatca ccaactttta cgagagtgcg ttggttgtaa gcagtacctg agtttgaacg
    21601 acggaatttt tggatgtggt aaacatccaa tgaaccatct tcacgacgaa cttctacctt
    21661 gtcagcatct gcgtaagtaa ctttaccatc atactgagca atcacagccg caccagaatc
    21721 gtgggctgct tggtattcca taccagtacc aacgtaaggt gcctgaggat taatcaatgg
    21781 cacagcctga cgttgcatat tggctcccat gagggcacgg ttggagtcat cgttttccaa
    21841 gaaaggaata catgctgtcg caacggcaac tacctgtttt ggtgaaacgt ccatgtagtc
    21901 aacaatatta gctggatact cttggttgac cccttggtga cgtcccatga caatcttctc
    21961 agcaaaggtt ccatcttcat tcagacgaga gttagcctga gctacagtat attcatcttc
    22021 ttcatcagct gtcaaccaaa caatttcgtt cgtgacaaca cctgtttcac ggtcaacctt
    22081 acggtatggt gtttgaacaa aaccatattt gttcaagtgt ccataagatg acaagttatt
    22141 gatcaaaccg atgttaggtc cttcaggtgt ctcgattgga cacatacgac catagtgagt
    22201 gtagtgcacg tcacgtactt catatccagc acggtcacga gtcaaaccac caggtcctaa
    22261 ggctgacaaa cggcgtttgt gagacaactc agaaagcggg ttgtgttggt ccatgaactg
    22321 tgacaactgt gatgaaccaa agaattcttt aactgcagct gttacaggac ggatattgat
    22381 aatttgttgt ggtgtcaaga cttcattgtc ctgaacagac atacgttcac ggacattacg
    22441 ttccatacga gaaagtccca aacgtacttg gttggcaagc aattcaccaa ccgcacggat
    22501 acgacgattt ccaaggtggt cgatatcatc tacacggcca agtccttcag ccaagttgag
    22561 gaagtagctc atctcagcaa ggatatctgc aggagtcacc gtacgaacct tgtcatctgg
    22621 gttagcatta ccaatgatcg ttacgacgcg atctggatca gttggagcaa taaccttgaa
    22681 tttttgaaga acaacaggct cagtcacaac ggctgcatcg tttgggatgt agacaatctt
    22741 gttcaagtcg ccatccaaat ggctttcaat gctttcaatc acgctacgag tcataatcgt
    22801 accagcttct accaagattt ctccagtttc agggtctacc aatggctctg caatggtttg
    22861 gttgagcaaa cgtgttttaa cattgagttt tttattgatt ttgtaacgac caactgctgc
    22921 caagtcataa cgacgtgggt caaagaagcg agctacaagc aagctacgtg agctttcagc
    22981 cgtcttaggc tcacctggac gaaggcgttc gtaaatttct ttcaaggctt cgtctgtacg
    23041 agagtccatt ggattcttgt ggatatcttt ttcaacagtg ttgcgaacca attcgctgtc
    23101 accaaagata tcaaagattt catcatcacc tgagaaacca agagcacgaa ccaaggttgt
    23161 aaatggaatc ttacgagtac ggtcgatacg agtgtaggtg atatcttttg agtcgctttc
    23221 aagttccaac caagctccac ggttagggat aacagttgaa ccatagccca ccttaccatt
    23281 tttgtctact ttgtcgttaa agtaaacacc tggtgagcgg accaactgag aaacgataat
    23341 acgttcacca ccattgatga tgaaagtacc catttctgtc atgattggga aatcaccaaa
    23401 gaaaacttct tgggtcttga tttcgcttgt ttctttattg atcaaacgga aggttacaaa
    23461 aattggtgct gagtagctag catcgtggat acgagcttct tctagcgtat attttggttc
    23521 cttgatttca tatccaacaa attccaactc cattgtgtct gtgaagtttg aaattggcaa
    23581 tacatcttca aacacttcct taagaccgtg gtctaggaaa gctttgaatg agtcagtttg
    23641 aatttcaatc aaatttggta agtcaagaac ttctttgatt cttgaaaaac tacgacgggt
    23701 acgatgtttc ccgtattgaa cgtcatgtcc tgccaagatg attctccttt gtaaataagt
    23761 tccaagcctt gtcaatcagg cttttctaat cgtcatatgg ttgtaaaccc cttatcaccg
    23821 tgtcctcttg atgaattttc agaatcttta agcctctgtt acaaatgctc aaaatcttga
    23881 aaaaaagcac aaaaagagca gctaaatctg actttttcag aagatttaac tgctgtgagc
    23941 cttgtctgga caatatttca gacaaaacct acgacaaatg attacccata ttatacccta
    24001 tttagctaga tttttcaagg ggtttcagta ggtttttggt aatttttttc ccatagaaaa
    24061 cttggcatca cattcgaatc acgctatggt acaaaaaact gaaaaaacta ttgactgaaa
    24121 atcattttca aggtataata ataaacgtta aggcggtata gccaagtggt aaggcacggc
    24181 tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc cttctataac ttgatttatc
    24241 aggtttcaaa tgaacagaaa gcccaatttg aagggctttt tttattttcc ctcgaataaa
    24301 tacgtataac tttaaaaact tttggagcga gtttgtggca gagttctttc catggcataa
    24361 ttcccttttg aaatcaattg aaaaaagctt cgtcacgcct ggtgacaaaa gcctctagtt
    24421 tattctgttt cttcttctat ttcgacttct gtgatttgga cttttacctt ggtaacacgt
    24481 ccattcttca ctttatcatt ggttaagata aactgtttgt tttggctgac caattcatag
    24541 ctgagtttct cagtcgttgg aatggttccc actcctgtca aataataacc agcgatggta
    24601 tcaacgtcat cactttccag ttcaacatca aagtaattat tgaaatcatt gagggtcata
    24661 gttccttgaa caatgtaggt atcctcgcca atctgatgaa catctattgc tgctttatcc
    24721 gtttcatcat caatttcacc aacaatttcc tctaagaggt cttccaaagt cactaaacca
    24781 gccataccac cgtattcatc cagcaagatt gccatttgtc tttgggtatt tcgcagttct
    24841 tttagcaagt catccacaaa aatagtttca ggtacaaaaa gtggatcttg taaaattctc
    24901 ttccaaacaa tattgtcaaa accgtccaca aagcctgcct taaggagact cttggtgtga
    24961 atgattccaa ttacattgtc cttatcccca tcataaaccg ggatacgaga ataattttgt
    25021 tttaaaatac tttggataat ggcttgacta tcatcctgaa tatccaccat aaaggcatcc
    25081 gttcgaggaa ccataacctc tcgtgccatc agttcatcga gcgaaaagac accttgtagc
    25141 atctcaatct catcagcatc caatgtttct tcactatttg tcagcatata ggcaatttca
    25201 tcacgggtca tcttttcatc cgcatcatcg aatgacatag gagtcaaatg gctcaagaaa
    25261 ttggtcgaag cagctaaaag ccaaacaaaa ggactgacta gttttccgat cccaatgata
    25321 accggcgctg tacgaattgc caaggcatcc tttagattaa gagcgattct cttaggatat
    25381 aattccccaa aaacgatgga aatataggtc aaaaatgcca aggatagaaa agttgccacg
    25441 gcttgtgctg tttcgccatt cccaagccaa gaggcaatca cacgtcctag agtatcagtt
    25501 aaactcgccc ctgataagat tgtaatcagg gtgattccta cctgaatggt tgataaaaag
    25561 tggttaggat tttctagtac cttcagcagg cgaatgtagc gtctgtctcc ttcttccgcc
    25621 ttttgttcaa ctcgggcacg attaagagaa accatggcca tttctgtggc tgagaaaaag
    25681 gcatttaata ccgtcaagat aaacaataaa acaaattgta gcaacaaatt ctgactactt
    25741 gggtcttcca tagttcttct cctaaaatag tatcttatcc tttattatat cacaaaattt
    25801 aatccaatac atattatttt tttcttagcg taacttccat ctctctccca aaactggaag
    25861 ttagtctaag acggatttcc actgatttca cgcgtttttc tcatactaaa agctaggttg
    25921 tgggaaactg gaagttagtt ttagaagtta ctattttttc ttagtacctg ttctagccct
    25981 gcttaaacta gtaaaaagaa ctcctacatc cataagtgac ataggagttt aggcttatct
    26041 tttactgagt tacagttact tctccagttc ggtaatccag ttgaagtccc ttttgaacat
    26101 tgggaactag aacattgaat tccaattctc catccgaaga cttggcttca atctgtgaag
    26161 ctgagggaac taaatcctcg tttgaagcgt agtaaagggt tacacggtaa cggacacgct
    26221 tgttttggtc caaggcttta cgcaccttgc tttcatagta gttttgacca gtcgaatact
    26281 cggcttgtgc ctgatttgcc caggctgtct gaacagcaat gtttttagga ttgcttgttg
    26341 aggcatcaaa accatccaaa ccaccgatta aggcatagcc taacaaatga cctctatcga
    26401 ctgcatgggt ataagagccc tttagattct tgacctgatg ccaacctgga ggagtccaag
    26461 aagttgaacc attcccagtt tctttacgat tcttgtactg acgagtggcc ttagacaaga
    26521 gggcattagc tacggttgga acagtttcct tgcccactgt ctttgtttta ttgtcagcgt
    26581 agggcttact tgaaaccttg gcatctagat ttgttttatt accattgacg ataaaagcac
    26641 ctgagccatt ccactccaga ctccccttta tttgactctt gactgcgtct gttaagacac
    26701 tctctgccaa tgcttgacta ggagcttcag gcgcttgttt tttctgacta agcttggttt
    26761 taggactatt aggtgccgac tgcatctgct tgatataata gctccctgta gacaaaagca
    26821 ataacactag cagtccgatt agtgtctgtc ttgttttttt gttcatattt ctccttatct
    26881 ttagaaaaag gctggttctc cagcctaatt tcctgtaaat ttatgaatca attcctgcca
    26941 ttttgctgga gacaggatag cccatggatc ttgacccttg cccaagattc cataacctac
    27001 cattaaaccg attcctagag ccagagtacc taaaatcagt actatgatga ctaaaagtaa
    27061 acgcttgact acgtagcttg atttcttatt catcttcatc acttgcctca atccgctgaa
    27121 tcttagcacc tagctgcgcc aacttctcat ggaaaccgta gtaacctcta tccaagtgaa
    27181 ccaatttacc gaccacagtt tctccctgtg ctaccaaacc tgtcaaaatc aaggctgcac
    27241 tggcacgaag gtcagttgaa agaacttctg ctccctgcaa aggctgtcca ccaacaatac
    27301 gagctgtatc acggataatc tcagaatgca agcccatgcg gcgcatctct tctaggtgtt
    27361 ggaaacgatt ttcgaaaact gtctccacca tggttgattc gccttttgca actgtcatca
    27421 aggctgtaaa ttgagcctgc atatctgttg gaaatcctgg gtggggcaag gttttcacat
    27481 gaacagcttt tagattttct agttgagaac gaacacgaat tccttcgtct tcttcaatta
    27541 cttcaacacc catttcaagt aacttggcaa tcaagggacg gttgtgctcc cagacagcgt
    27601 ctcgaatcaa gacatcacca ccagtcatgg cagcagctac cataaaggtt cctgcttcga
    27661 tacggtcttg gactacattg tgagtcgtac catgaagttt ctcaacacca gtaatggtta
    27721 tagtctctgt accagcacct ttgaccttgg ctcccatttc attaaggaga atggctaagt
    27781 caacaatctc aggctcacgc gcagcattct caatcactgt caccccatca gccagagtcg
    27841 ctgccatcat caagttctgc gttgcaccaa cacttggaaa gtccatatag atatgagcgc
    27901 catgcaagcg ttctgccttg gcttcgatgt aaccagctgt ctgactaatc ttaaccccca
    27961 tagcttccag acctttcaaa tgaagatcaa taggacggct accaatcgta caaccacctg
    28021 gcatggatac cttggcatga cccacacggg caaggattgg ccctaataca acgatggagg
    28081 cgcgcatctt gctgacatac ttgtaagggg cttcctcagt gatgtcgcca gtagcatcca
    28141 ccttgacaag atgagcttcc tcatcaaagt caaccttggc attcaaacca ccaactacct
    28201 gattcataat aaagacatcc gacaaaatcg gaacattctg caagacggtc tttccttcac
    28261 ttgctagaat agtcgctgcc aacaagggta agactgcatt ttttgctccc tcgatcgtca
    28321 cgcttcctac cagacgatta tcgccacctt gaaccacaat tttatccata ctcgtttcct
    28381 ttactcttga tttcataata atcctctaag cgcttcttgc cacaaatgat acaggctaat
    28441 aaagaaagaa ctcaggatgt agcctatgac aatgctaaaa aaggctacta ataaacgaac
    28501 ttttcttgta ttatcatctg tcacttttaa aaccttctcc catctaacaa gatcctttaa
    28561 aaggtaaaaa ctcacataaa taaagaacat atgactactt agagtgaata ataattgaac
    28621 catttgacta ttataccatc ttctctgttt gtgcgctagt ttggaaactt cactcaaaaa
    28681 ttagggattg tttttcaagt aatcaatcgc atcttgtagg gttttaacgg gcacgatttt
    28741 catatccgtc ttgattgttt tagccgcttc tagggctgtt tggtagttgt ttttcgcgtc
    28801 cggatgcgcc ttttgttctt cttcgctaac agggttatca ggagcaaaga aaatagcagc
    28861 acctgcccta gccgaagcta caaccttctt atcaatacct ccaatgtctc ccacattacc
    28921 atcgcggtca atggtacctg taccggcaac aatacgacca ttacgaagat ctgggtgagc
    28981 tatttgagta tagatagcta gactaaacat gagaccagca cttggaccgc caataccagc
    29041 tgttgaaaag ctaattggga cattgctgat tacctctgta cggtcaatca agccgattcc
    29101 aattccattt ttgccatttt ccaaggtgat gatttttcct tctgcagact tggtttgccc
    29161 atcctcttca taggtgacct tgacggaatc ccctaatttt tgagaactga cgtaatcaat
    29221 caagtctttg gaactatcaa aggtctgatc attgactgct gtgactgtat cagagatatt
    29281 gagaatccct ttaaaggttg aattatccgt cacattcaaa acataaactc caaagtactt
    29341 gagttcgata tccttaccag ctgtttttag tccttgatac ttggccatat tttgcgatgt
    29401 ttgcatgtag aattgattga ttcgcataaa ttcaacatcg gaagaaccac ctgtagtctc
    29461 ctgagcacta cgaatatctg taaaaggtgt caaccaagca taaatcatat gagctaaagt
    29521 ggcatgttga acaccaaccg taacgaattg ataggcacca gcttccttat cttctgtgtc
    29581 atttacttta aggacttggc gaatatcttc cgaaccacct ggaacctcta tataataagg
    29641 caagggcact acaaatgcca agaaagtcac aatcaaggcc gcaatgacgt ataagggcca
    29701 tctaatcttt tttttcattt cttatttcct ccaaaatact ctcgggaaca tagcaggcaa
    29761 tatcctgacc aaacttcaaa agctctctaa cgcctgatga actgatatag agatgttcag
    29821 gtcgactatg taaataaata gtctctatat cagaagacag ctgatgattg tagtaatcaa
    29881 aactggcttc atattgcaaa tccgacgcat ttctcaagcc tcgcactagg caagtagccc
    29941 ccagtctttt tgcgacatcg accaccaatt tatcatgaga agacacgact ttaacatttc
    30001 ccaaatgttt cacagccttt tctaaccccc gtttacgatt ttcaagaggg agaaatcctt
    30061 gtttgtgggg attaaaaaaa atacccacat aaagcttatc aaagagtctg ctcgcccgtt
    30121 caatcatatc cagatgccca tttgtcatcg gatcaaatga gcctgtgaat aagccaatct
    30181 tatctgacat agactgttac cttactaatt ccataaatct tttccttcca gatacccaga
    30241 caggcaattt cttctggaag ttcaacggcc ttatccgtct cgcacacaac cataacatct
    30301 tcagaaaaaa gctctctctc agccattttt tcaatatctg ctacgatttg ttccttggca
    30361 tagggagggt ctaagaaaat gaggtcaaat tccccagata cctgttccaa tgccctttct
    30421 gcatccatct tgaggagttg aaattttcca acttccttgg tcatctggat attttcagcc
    30481 acgatggtct gagccttacg gtctcgctcc accaaaacag cactggacat gccacgcgat
    30541 actgcttcga tagataaacc accactacct gcataaaggt ccaagactcg tcccccttca
    30601 aagtagggac caatcatgtt aaaaatggct cccctaacct tatccgaagt aggtcttgtt
    30661 gtcttgcctt ctagtgtctt aaggggacgt cccccataga ttcctgatat gattttcata
    30721 ctgtttatta taccaaatta tagacaaaaa gagaaagaaa accgaacctt gcggttcgat
    30781 tctctacaaa atattttcgt aagtatcgcg gacttcttga ggccaaacac ttgtttgcac
    30841 ttctccgatg tgtctcttgc gaagtaggaa catggccata cgagattgtc caattcctcc
    30901 accgattgtc aatgggaata ggccattcaa caaagacttg tgccattcca attccaagcg
    30961 gtcttcatca cctgtaattt ccacctgacg tctaagagtt tcttcatcta cacgaattcc
    31021 catagaagac aactcaaagg ctccacctaa agactcattc cagacaagaa tatcaccatt
    31081 tagacccttg tagccattct cagactcgct tgtccagtca tcatagtctg gtgcacgtcc
    31141 atcgtgcggt ttaccatctg gcaactcgcc accgatacca atcaaaaaga cggctccaaa
    31201 ttctttacaa atcgcatttt cacgttcttt cggtgtcaag tctgggtagc gttctaccaa
    31261 ttcttctgta tggataaagg tgatttgttt tggcaagata gactcgatgt catagcgggc
    31321 ttcaacagct agctcagtca ggcgaatagc cttataaatc ttctcaactg tttcttttag
    31381 ataaacgatg ttacgcttac catttggaat aaccttctcc cagtcccact ggtcaacata
    31441 aacagagtgg gttgcatcca aggaatcctc atctggacga agggctttca tgtggacaaa
    31501 gagaccctct ccttcaccaa agccaaaacg agccaaggtg tggcgtttcc atttagcaag
    31561 tgagtgcacc acttcataag tagcatcagg gatttggaga accttgaccg atactggatt
    31621 ttccacacca gacaggttgt cctgcattcc gtcaccgacc ttactcaaga taggaccttg
    31681 aacttcgaca acttctagct tatctttcaa atactgggta aaagtgtttt tgacaaagga
    31741 aatttcttct tgttgatgga taaaactttt cttcatagac aactcctcaa aaatttaata
    31801 aacgtattat acacctattt ccaagaaaag aaaagagaaa atttaaaaaa aatcagtgtc
    31861 actcaaaaca ctgatttcat agacctttta gtcattgcga ccaaagatac gtagaatact
    31921 taggaaaaga ttgataaaat caagatagat gctgagagcc attgacacca cccagcctgt
    31981 cgctacacga ccttgtgatt gttcataggc gaggcgaatc ttttggttat cccaagcaat
    32041 caaccctgaa aaaaccaaaa ccatggctac gctaatcata taatcaaaga agccactagc
    32101 caagaaaata ttgactacca tagcaatcag taaaccaatg agagctgcca tcattgctcg
    32161 accaatccca ctcaagtctt tcttggtaaa aataccaact gccgccatga caaagaagag
    32221 aagggcgctc gatacaaagg cagataaaac tgtacccgga gtatagaaag ccaccacaaa
    32281 actaagggta aagccgttta aaacggagta aagtaaaaat actggaagag cagctggact
    32341 atttcttgaa gccatgctac tggcaacgaa aaccaaagcc aactccgcaa aagtagcaat
    32401 ggtcaaccag agacgcccct gcatcaacaa gtaaaccaac tgagactgaa agaccgtcaa
    32461 cataaggcct gataccaaag cagatagtcc gattcccaga ccaacaaagg cataaacctt
    32521 agcgtaaaat tgattgagac ctgcacggtc atgtataata gtgtgattca tccttttctc
    32581 cttttctgtg aacatctttc cttgattata acaaaaaaag ttaaaattag cttaaatgga
    32641 agattaaaat accggctgca actgcaacat tcaaactctc ggcctgcccc ttcatgctaa
    32701 tatggaccaa ctggtctgca ctttcagcca taaggggact aattccttga ccctcatttc
    32761 ccataactag tacaaaattt tctatagaag gcagttctct gtaatcaaca gaatctttag
    32821 atagggttgt tgctagcact gggatagcta cctttttagt ttcgtcaaga agcgcttgac
    32881 tagtcatccg gtaaatgggc agatggaaat gactaccttg catggaacgt agggttttga
    32941 gactgtagat gtctgccgac ttatctgaaa caatcactcc tgtaaaacct gctgcatccg
    33001 cagttcgaat gatagttcct acattaccag gatcttgcac atcttccaaa aacaagaact
    33061 tgccctgact caaatcagct tgtcctactt cttctttttg aaccacggca acaattccct
    33121 gtggagtctg agaatccgcc aaatctagca aaatatcctc tgaaatccag acagtttgcg
    33181 gaaaagcagc taactgattt cgataatttt ctagggcaaa gattttctca atcgtcactc
    33241 cagcttggac agcttcttca aacaagtgcc agccttcaat caaataggca gacttgcggt
    33301 attttttttg gtgtaatttc ttagcatttt ttaccacaga attggctttt gaggttataa
    33361 tagtcataga aatattataa cacaatcaaa ggggtttggt atgcaaaagg ttagaatgat
    33421 tgcccaaggt agggtgcagg gagtcggctt tcgttggggt gtttatagcc tggcccttga
    33481 aatcggtggc atcacaggtc gggtatggaa taacgacgat ggcacagtgg aaatcttagc
    33541 ccaagcagac tcatctgcta tcatggcaaa atttatccaa gaaatccgaa aaggaccgac
    33601 acctttttca aaagtaagct acttagatgt caaactaagc aactttcctc cctactctga
    33661 ctttaaaatc gcaaattagg tctccagaac tattgtatat tttgtaaaaa aacagtagaa
    33721 tagaaaggta taatttttaa agaaggaata aaaacagtga aatctattaa acgttttgca
    33781 ttctcggcta tgggagtggc tatgttgctt gtcttgactg gctgtgtcaa tgtcgataaa
    33841 accacaggtc agccaacagg atttatttgg aatacgatcg gagcgcctat ggctgaagcc
    33901 atcaagtact tcgctactga taaaggtcta ggctttggtg tcgctatcat tatcgtaacc
    33961 attatcgtac gcttgattat cttaccactt ggtatctacc aatcatggaa ggcaacgctt
    34021 cactctgaaa agatgaacgc cctcaagcac gtccttgagc cacaccaaac gcgtctcaaa
    34081 gaagcgacta ctcaagaaga aaaactcgaa gcccaacaag ctctctttgc tgctcaaaaa
    34141 gagcacggta tcagcatgtt tggcggtgta ggatgtttcc ctatcctcct tcaaatgcct
    34201 ttcttctctg ctatctactt tgctgcccaa catactgaag gggttgctca agcaagctac
    34261 ctaggcattc ctctaggttc tccaagtatg attttggttg cctgtgctgg tgtcctttac
    34321 tatcttcaat cgctcctttc acttcacgga gtagaagatg aaatgcaaag agaacaaatc
    34381 aagaaaatga tttacatgag cccactcatg atcgtcgtct tctccctctt ctcaccagct
    34441 agtgtcacac tttactgggt tgtcggtggt ttcatgatga ttctccaaca gtttatcgtc
    34501 aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg aagaactagc caagaaccca
    34561 ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag acgttacccc tgaacaacca
    34621 actgctatca caagcaagaa aaaacacaaa aatcgcaacg ctggaaaaca acgttcgaga
    34681 taagaagaaa aaggcttagc tgatttgcta agtctttttg caagtcaaaa gcccgatgtt
    34741 tccatcaggc ttcttttcta tccatgtaca cgtttcatat aatcttgata actttcggta
    34801 tccatgagtt gtttagcgtt cttgacgcga tctgctgttg gtggtttgac tccttcgagg
    34861 gaatatggaa ttccaagttc acgccacttg aactcaccca tggtgtgata aggtagaatt
    34921 tcaaacttat caacattttt gagggtcttg acgaacttac caagttcaat caagtcatca
    34981 tctctgtctg tcaatcctgg aactagcacg tggcgaatcc agacaggttt tccaatatct
    35041 gatagatact gggcacaagc caagatattt ttattggttt ggctagtgac aatcttgtgc
    35101 tgttcttcgt tgatttcctt gatatccaaa agaaccaagt cagtgacagc catgagtttg
    35161 tcaaacttct caaggtaacg tggtttatta cggaaaggaa gagcacaggt gtccaaggta
    35221 cagtggattc cttgttcctt agccttggtg aagagagcaa tcaggaaatc aatctgcaag
    35281 agagcttctc ctccactgac tgtaatccca cccttatttc cccagaaacc acggtagcgc
    35341 aaggcctctg tcaagacatc atctaccgtc cgttcacgtg acttattgga ctccatagcc
    35401 caagtgtctg ggttgtggca atactggcaa cgcatgtgac agccctgcaa aaagacaata
    35461 aagcgaatac caggcccatc tactgaccca aagctttctg tcgaatgcac cattcctgtc
    35521 acttgtccat aatcaattgt ttcttcagac atatcgttac cttccttgaa aacgttttat
    35581 agttttatta tatcacgact tgaaggaaaa acaagatttt tgcctatttt ttagaaagca
    35641 atctgttttt caatttcatt ttcaatctat tatcagatta ttcttcaaaa tcgaagccat
    35701 ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg gatttgacgg gctttacctt
    35761 cttcggtata gaggatttcc gcagaacgta atttggcatt atactggtag cccattgaaa
    35821 atccgtgggc acctgtatca tgaatgacca gcaaatcacc gatttctgta tgaggcagtt
    35881 cgcgattaac tgcaaattta tcattgtttt cacagagtga accgaccaca tctaccactt
    35941 cagctggtcc atctggatgg gtcacgttgc taatatgatg gtaagctccg tacatagctg
    36001 gacgcatgag gttgactgct gaggcatcca cacctagata ggtacggtag gtttccttct
    36061 tatgagtgac tcttgtgact agagcaccgt gaggtgccag cataaaacga cccaattcgg
    36121 tgaaaatctt gacctgacca agacctgctg acgtaagaac ctcttcatac accttacgaa
    36181 ctccctcacc aatcaaggcg atatcgttcg gctcctggtc tggatgataa ttaacaccaa
    36241 taccgccaga aagattgata aagtctagcg aaatgcccaa cttttccttg atttcaacag
    36301 ccagttcaaa gagctgacga gccaactctg gataatagag atgggtcacg gtattggacg
    36361 ctaggaagga gtgaatccca aaagtcttgg ctcctttttc cttcaagata gcaaaggctt
    36421 caaagagctg gtccttggtc atgccaaact tagcctcccc aggattgtcc ataatgtctg
    36481 tccccagttc aaaaacgcct ccaggattat aacgacaaga gatgatttct ggaatgcctg
    36541 ctactctctc cagatgttca atatcttcaa aggcatccaa gttaatggtc gcacccaatt
    36601 cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga agagaacata atctcagaac
    36661 ccagaaagtc cagtttatgg ctcatcaaaa gctctacata actagagcag tccacaccac
    36721 aaccttcttc ttggagaatt ttcaaaatag ctggagttgg agtagcctta actgcaaaat
    36781 attccttaaa gcccttgttc cacgaaaaag cttggttgac ggctcttgcc ttctcacgaa
    36841 tccccttctc atcatataag tgaaagggag tcgggaactc ggcaacaatc gcttctaact
    36901 cttctctatt gataaatggt gttttcataa gcttccttct attctgtttg caaagaaagg
    36961 ctgggacaat cgttccaacc tttagttcta tctcttattt atcttcgtca aagatattgc
    37021 caacctcaac atcgatggct tggttcttga catcaatatt ggttaccttc aagagtgact
    37081 tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc cgcaaagacc gctacacctg
    37141 ccagttctga gtcgaactcg cgcaagagac taatcatacc attgaccgtt ccgccacctt
    37201 tcaagaagtc atccacaatc aagacacggc tgcctgcctt aagactacgt tttgaaagga
    37261 acattttctc gatacggtca ccacttgaac ctgaaacata gttgacgcta acagttgaac
    37321 cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga gacattgagg acattggcaa
    37381 ctgcatttgc aagtggcaca cccttagttg ctacggtcat aaccgcgtca attttttggt
    37441 ccataaagct tttggcaata atacgaccaa tatttttcaa gatggctggt gtgctaagca
    37501 aatcagacag atagatataa ccacctggca agatacggtc actttctgac aacttggtac
    37561 gcaagtcttc aaccatttcc ttagcatcct gactcgaaat agacggtgtg aagatgacac
    37621 ctccgccagc cccagtcact gtctggatat gaccgatttc aatttcctca aaggcgcgtt
    37681 tgataatgac gatatcttct gagatggatg atttagcaga ctcatacttt tcagcaaaag
    37741 tattgagact agttagttta taaggattat taatcaaata gttggaaatg acaaccatcc
    37801 gatcacttct tcttaatttc atttctattt cctattccat ttttattcaa aaaatcaaaa
    37861 agcaaactag aaagctggtc gctggtggtt caaaacactg ttttgagatt gtcaatagaa
    37921 ctgacaaacc ctgtaatata cctgcatata tacatacgac aaggcgatac tatcctagtt
    37981 tgaagagatt ttcgaagagt attcattttt gtcttttact tattatacca tattcacata
    38041 aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc ttaaattatc aatctaaatc
    38101 tggtttatag aaggaacgat tatccatagc gaagatttta ttggtcatct ctcctttatc
    38161 caccaaagcc agagctgttg acatcatcat catgcttgca tccagattgt caatcatatg
    38221 gataatctct gcctccataa tacgtggacg gactggactt ccatattcaa gcaagccgtg
    38281 gtgactgagg atgacatgac gaagcaaaac gacttcttcc ttggtatcat cgatgccgag
    38341 ttccataact gtcttggtaa tttcgctatc aatgagagcg atatgtccaa gaagattacc
    38401 tcgcactgtg tactctgtct ggtctggccc cgtcaactcg ataaccttag ctaagtcatg
    38461 cagcataatc cccgcataga gcaggctctt attgagctga ggataaactt cgctaatagc
    38521 gtctgccaaa cgcaccatgg tcgccgtatg ataggccaag cccgtttcaa aggcatggtg
    38581 gttggtcttg gcagctggat aggagtagaa ttccttatca tacttggtgt agagatttcg
    38641 gacaatccgt tgccagacag gattttcaat tttgaaaatc atttgcgaca tgtagtcacg
    38701 aatttccttg acatcaactg gtgacttgac cttgaaatca gctgggtcat tgggttcacc
    38761 agcttgaggc aggcggagag taatttgatt gacttgaggg gtattgttat aaacttctcg
    38821 gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc tcaatgttat gaggttgggc
    38881 atcccagagc ttcccatcaa tctcgccact atcatcttgg aaggtaaagg ctaggtagtt
    38941 tttcccagct cgagtttgcc tcaggtcagc tgatttgatt aggtaaaagc cttcaaataa
    39001 ctcatctttt ttcatgtgac taatcttcat attcttcctc attttcttga aaatggagta
    39061 gatcaagcgc aggctcacct tctgacaact caatgtgacg gagcgtccgc tcgatagcta
    39121 tggtacgacg gtttaataat tcatcaatat tgccagaggc atgttggaga tgtttttgtg
    39181 ccttgaccag aataccacca aacttgccaa actcggtctt gacactggca agagtcttgc
    39241 tgatatggtc ggcactcttt tggatattaa gggtcttgaa accaactgat agggagttaa
    39301 gaagggctga tagggtactt ggtcctgcaa cgataatctg ttcttcccgt ctcaaatcat
    39361 caaagaagac cggattgcgc acaatctctg aataaagacc ttctgtcgga acaaacaaga
    39421 ttccaaaatt ggttgtccga ggcggtgcta tgtacttgct cttgatatcc ttggcaaagc
    39481 gcttgacgct tgctaggagt gacttacgac agcgttcaat ctcatccttg tcacctgtct
    39541 cataggcttc ttccaagcgg taataatctg ccagtggaaa cttagagtca attggcagat
    39601 agacgtattc ttggtcgcct tgtccgggta acttgatggc atactccact cgttcactag
    39661 agttttcaac cgttgcgtat tctcgttcgt actgggcagg tgtcatgatg tcttcaataa
    39721 tttgccccag ttgcaattct cccagaatac ctcgcgtctt ggttccagag agaaccttgt
    39781 taagagctcc gacatcacgg gcaactgtct gcatttctcc aaggccacga ttgacagact
    39841 ccagttgttt agaaactgtt tcaaaggaag cctgtaagcg tgtctgcaag gtcttttcta
    39901 gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg ctcatttgat tcctgcaagg
    39961 cttggagacg ttggtctgtc ttgtctctag tttggaggag attatctgtc atttcttgac
    40021 ggacttgggt caggccttgg tgcaattcaa tccgcacttc ttgcaaacgg tcgctgacag
    40081 ccacttccaa atctttttgg tctaactggc tggcttgtct ggcttggtca aagcggtaat
    40141 ccaactggtc tgacaaatga tctgcctgat cctccaagct cttacttaag tgtttctcct
    40201 gcctatcctg cctttgccaa atcagaaaga gaccagctag gttggcaatt aataatagaa
    40261 taagtaaact ttccatccta cctcctgtcc ttgctatgca gtacgaccac ataaccatct
    40321 gggcaagtta ccgacacttc cctatctata tattcgttag aagcgtacac ttttttaaag
    40381 aaaaaattct cctctgtcaa ctcatactta gctccaagaa tagtcagctg gctatcccga
    40441 actggcataa aggctagata gtcgtagtct gaacgaggtt ctagctgact ggtcccttct
    40501 gaacaatagg caatcaaatt ttgcccatcc tcaatttcta tttgacgcat atagggtgcc
    40561 aacttaggat tgctaggtag aaagacattg gccaacatat ggtcaatacg gccacccaag
    40621 gcaccgaaaa tagtgacctg agcctgagga ttttgttcaa agatggttaa gagagccaat
    40681 tccagatctg tatcatcctt ttctggtcgg gcttggacaa aatactgggc acgtttttga
    40741 atcacctgtc gctcttcttc cgtcacagaa tcaaaatctc cgactgctag agcaagaggt
    40801 aagtcttctt ccaagaccca gagcgagcct cgatccaccc caacaaaagc atcaaaatct
    40861 gtccgataat gaccgcggtt tccgcctgca aaaactgcaa ccctagtcca gttgttttct
    40921 gagagtttgt actcgctcat tgacttctcc cttaaagaca taggaacctg ctacaaaaac
    40981 agtcgcacca gcttctttgg cttgagcaat agtttggtca tcaatcccac catccacttc
    41041 gatttcaaag ttcaaacctt tttcctcacg aagagcaacc aactcacgaa ccttatccat
    41101 ggtttctggc agaaaggctt gcccaccaaa acctggatta accgtcatga ctaaaacttg
    41161 gtcaactaga tgaaggacgt gcttgatggc ttcaactggt gtgccaggat tgataacgac
    41221 tgaaggctta actccgagtg aacgaatttt ttggagggcg ccatgaatat gaggtgttgc
    41281 ttctacatgg atactgatga tgtctgcacc tgcacgcgca aaatcttcca gatgatgctc
    41341 agggtttgac accatcaagt ggcaatcgaa aaccatctta ctatgaggac gaaggctctc
    41401 gaccacacct gcaccaaaac tgatttgcgg tacaaaatga ctgtccatga tatcgatatg
    41461 ggcatattct gccccagttg cttctagacg tttgatttca cgttcaaagt tggcataatc
    41521 tgctgccaga attgacggag caatcttgta ttgagacata ggtttctcct tattttggaa
    41581 tttttttgct gactttttta taggtttctc tacgattttc aatttcacta aggaattgca
    41641 ggtaattgtc aaaacggaag gttgcaataa caccctcttc aacagctggt ttgacggcac
    41701 aagacggctc atgggtatgg gtacaagtac ggaacttaca atctcggcta acagtagcaa
    41761 tctctgggaa agcctgattg aggtcttcag cccttgatac ttcatagtcc aaggatgaaa
    41821 atcctggtgt atctgcgatt ttacccccgt tgagattgta aaaactaaca gctcgagtgg
    41881 tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt ttcaagattg aggtctggtg
    41941 cgattttatt gagaagagtt gacttcccaa cacctgtctg ccccataaag accgtaacct
    42001 tgcctgttaa caaagacagg agttcctctt tactggtcac aaagtcatag ccgatgtcac
    42061 cataggtctg ctggtaaaaa tccagttctc ccctatcttc caacaaatcc attttggaaa
    42121 tatagacaat gggatggatg cccttgtgct ccaaaagaac caagaaacga tccagcaaat
    42181 tgctgttaaa atcaggttcc ttgacggaca tgattactac agcttgatcg atattgacaa
    42241 taggcggacg aaccagactg tttttccgtt cgtgaatttt gaggatatag ccttctgaat
    42301 tttcctcggc agagaaatct acccagtccc caacataagg ggtatggcct tttttacgga
    42361 aattcccacg cgcgcgtgtt tgataaacct ggccatcact ctccacatag tagaaacctg
    42421 ccaaggcttt aatgatttgt ccctgcatct tagagtcctt gccctttaag tgcgtctgct
    42481 agaccggcaa attctgccaa gctgagagct tccccacgca cacttggtga caagcctgcc
    42541 tggtccaaag ccttggtcag cttgtccttg acctcttcag tcttaccaaa gtaacctgtc
    42601 aagttattcc acaaggtctt gcggcgatgg gtaaaactag ccttggaaac cttaaagaaa
    42661 aagttctcat cttctactgc tacggctggc tctggacgac gcaccatttt caagatggct
    42721 gaatccacat ttggcgctgg cacaaagacc gtacgaggca cgataaaggc aaccttggct
    42781 gtcatgtaat actgcacggc gatagacaag ctaccgtaag ccttggtgtt aggctgggct
    42841 gaaatgcggt ccgctacttc tttctgcatc atgaccacaa actcacaaaa aggaatgcca
    42901 ctctcaatca agtgcatgag aataggcgtc gtgatgtagt aaggcaaatt agccactacc
    42961 ttgattggca ggttaggatt tttaaaattt tggatatgtt gcgccaaatc aaccttgaga
    43021 atatcttcgt taactacagt cacattatca aaatcacgca gggtatctac caaaattggc
    43081 accaaacggt ggtcaatctc aaaagccatg acttgggctg cacgctcagc cagaaactcc
    43141 gtcaaggcac caatacctgg cccgatttcg atgacattga cctggtcatc aatttcagcc
    43201 gtatccacaa ttttttgaag gatattggta tccgtcagga aattttgccc gaaggacttt
    43261 ttaaaggtaa aaccgtgacg ctccagcact gccttggtca ctctataatc tgcaattctc
    43321 atctattctc ttttctatta tctgttacta ctattgtaac acattcccct tgtattttgg
    43381 gaatgaaaat cataccaaaa aactatcttt cctcatgaag aaagatagtc ttggaaatct
    43441 ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca aaaaaatcag cttcttgata
    43501 acttcgattt tcaggtaggg tcaaatccac atcctcctcc acatcatcca ctgtcagttc
    43561 aaccgtctga ggtaaatttt tcaaacgata atgcttttgc ctttgccctt caatactagc
    43621 aaaatcaagc aaatagccat gcactcggat ttgaaccaaa aggagatgat tggtcatatt
    43681 ttccatgatg aggatatctt ctaaaccacc tctggcacta ggataatcag ataccctgcg
    43741 aatacggatt ttttcacaca tgagcaagtt tcctcatatc aatgatttca tcagccttat
    43801 tccagactag gggattatgg gtcgcaatga tgataattcg attttcatct ttcaaatcca
    43861 ccaagagatt cataacctcc tctgaatttt caggatcaag agctgctgtt ggttcatctg
    43921 ccaaaatcaa gggtggattt ttcaaaatag tcttagcaag ggcaactcgt tgggcctctc
    43981 ccccagataa agtataaatt ttttgttcta aatccaaata ccctagatta actttttcta
    44041 aagcccccac ttgcctttcc aaacgttcta cttttgagat tttctgacca acaaaaccca
    44101 aatccaaatt ttctttgatt gattggtttt ctaagaggcc aaaattttga aagagatagc
    44161 ccatctgatc tcgaaaatac tcacgagtgg gaatggtttt taaatctttc ccctgataga
    44221 gaacccttcc tccatctatc ttttctagct ttcccaagat attcagcagc gtcgtctttc
    44281 cgcttccact ctttccgatt aaggcataaa ccttgccctt ctccagcttg agattcaaac
    44341 cagagaaaat cgcgcggtca ttaaatttct tttccaatcc ttgaatatca atcatcttat
    44401 tttcctttca atactgccat gctaccagct tcttcttttt tgtcctgcct tactaaaatc
    44461 aagagggcgt taagcgtaaa caaagctaca actagagcgc taatcaaacc atctcttgtc
    44521 aaaatactag ataggactag gccaagcaag agaactcctc cttgcgccag taaatacttg
    44581 ccatgaagct catagattgt cataccagca agacgtttaa tcataagctc ccgtctgaac
    44641 tgctcaaaat agagaagatt catggaatca aataacaaga tagccgtaga cagggtcaaa
    44701 atcgtcccaa taaggagaga gtaaaactcc acccgtttgt catttagtac cttggcaaaa
    44761 aatagctggc tttttaccaa gtaagaaacc ttgtgataca gaccttgctc ttttagagct
    44821 gtgatgctgt ctccatatcg atctagtttc aaggcactat tagccgtagt tccccacaac
    44881 atccctgcaa caggtcttgt tccagtcgct tgcggcgtta gaactacaat aatcggatct
    44941 tttaggtact ggcgtgttgt cttgtaccca tcattataga ggaaacgttc ctgtcctgtt
    45001 tctgtaaaag ctagccttac ctgtgggaag tagtgtttct gactcgtcac ttctacactt
    45061 tcagatgaaa agttttgcag gtaatctgta aacaatcctt ggtagtaggc agactgctct
    45121 cgcaagctct caggcaagat cagcccaaac tctccctcag acaagttttg catcttgtcc
    45181 ataaactctg aagaaacggt aatcttttct tctatcagat agcgcggcga gacatagata
    45241 acattccctg acggtatgta gtcactgaga cgattgccat ctaggtccac ttctgctcca
    45301 tctgagaaat tgtcaacatt gctcataata taaaaagagt ctgtattggc taaccgttct
    45361 tcagtaaatg tctgccactc acgattatcc ttacgcgttc cttcttcatc ggcaaatgca
    45421 ctagaccaac caaaggatag acggtaacgg tctgaggact ggctccattt attgctagct
    45481 ctctccattt cctgcatttc acggtagtgg ggtaggagag ctgtcgcact cgatccgacc
    45541 accaatacag ctaagagttg ccccaccatc atcaatgtca tcatccgttt gagagggagt
    45601 ttccctttca atagatccac cagactattt tcctgtaaac caagtagatg gacgacactt
    45661 agtaaggtag aaatccctgc cagggtcaat ccataaagta gaagagcaat gatgaccagt
    45721 tgtaccgttg ccataaacaa ggcaccttga taccagagaa tccccaatcc caaaagactg
    45781 gataccagca ctgagcagat aagctgtctc acatcttcta acactggtct gagagcaact
    45841 ccaaacaagc tctcaccagc tattaagcga atccctgcct gacgaaggga tttgatccga
    45901 taaatcaggg tcagactcat aaaggtcagc agaaaaatag ctaaactcag tagcaccata
    45961 ggggtggccg ccaatagtaa gactatcgaa aatggatctt ctccattcga aacaaagcct
    46021 tgatagccaa gttctttcaa ggtggtctgt aagctcactc catccaaact tcctgacaca
    46081 atcaagtaag accctaataa atcactcgtt tctgcactct ccttggagga aatggtcaga
    46141 ccttctggaa gctttccctc accataagtg gcataggtaa agcgtgtttc tccagcttca
    46201 tttggctcaa cgattcgacg ggcgatgaga ctattatgct ctaccgccaa gtgactcaaa
    46261 gcctctgtca cctcttcgcg actagctact ggttgattta tcatcattcc tgtcacatca
    46321 acagaaggat agttaccaaa taaaatctct tctcgatggt caacggaagt tatcaccata
    46381 taaagcgata ccaataccat tgaaatcaaa ataaataaac gtttcatcat ttcctccaaa
    46441 aagttacttg gtcacttagt gagaaggtga ccaagtaaag ctaaacaata gggctatacc
    46501 attctaaaca ttatagtaga atgcaacttt ctctccccaa gaagtacgaa tccatgcacg
    46561 agaagtccct ccagcaccag catatccctt gtcagatgaa ccagtttttc tgctaacaac
    46621 tgttgaacta tggtattttg aagggtgata gtagtttgag taagcaccac cgttacctga
    46681 accataagtc caaacaccac cttctgggta ttgaacggct gcagaggcaa ctgctacact
    46741 tccacctaat gttgctgcaa tgctcgctac aagagctaat tttttaactg tttgtttcat
    46801 attgatactc ctctattttt gattacaaga ttgttgagtt acttgctcct ctttccatta
    46861 tcaacgttga tactattata ttaccaaatg atattctaaa attatttgtt tttctctaaa
    46921 ttgtcaaaat agcaccctga aatgaacttt tatagtcatt atactccatc tttatcacac
    46981 tatcaaggac atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct
    47041 aaaaaaacag ttctaaagac gaactttaga actgttttga tacgaggata aggacatttt
    47101 tgtcactgat tcactatgtt tataaatatt tttttaaatc ttcttgccat tgtttttcta
    47161 acatagtaac taaataagaa ttttctatta tatcagcaaa tagcttcgat ttctgataga
    47221 actgttcggc agaaacataa tcattgttta ttattagaga taatttccac tccaacatta
    47281 atataattgg tttcttctgg aaatcttgtg ttttttccat tatatgatta aggctaaaga
    47341 tataagctcc tagtgaatca taagacgaca agttatccaa acaggctaga cccgaaaaca
    47401 aagtgttact taaagcaaac agatattctg atgcaattaa ttctacatga tttgtcaaac
    47461 gaactaaaaa cgaatgaatt ctgttaattt cttcaatctg attttgacct tgttttatct
    47521 ttgtaagcac tatagcaaaa tataagttga taacttctaa ttcatttatc aaaaacaatt
    47581 ccttatcata aattgtttta aaataatcgt ccagtacggt ttccccgtat tctggtcgtc
    47641 cacttcgaat aacatctatc gttgctctag tagcttcaaa ccatactttt tcctcattag
    47701 gaagttgctc ataaaataaa tcctctatct cttccaaaca cgcttccttc ttatcgtact
    47761 cctcttcttt accatagatt ggttcacgta aaatctggta tttcaattct aaataagcag
    47821 aaggaagagc tgaaaaatcc ggcataaggc tataaactgg aactcctagc cggcgagcaa
    47881 tataggctaa cttgggcaaa ctcggttgcg aagctccact ttcaattcgc gacagttgac
    47941 gaactgtcag ttcttgctca tctccacaaa aatctggacg actaattcct ttttctatcc
    48001 gaatctcttt aattttttga ccaattaaca tcagacgcct cctattctac ctgcttcgaa
    48061 aaatactgtg aaacttaaaa aattgtaacg gctacatctt tcctactcat aagatttcat
    48121 agcttcttcc acttctgcca aagtaacccc aaacaactct aggcgtttga ggagttgctt
    48181 gccgttggaa tagccgattc ggagagtctc tccgaggtat tctctacgct tacggctgtc
    48241 tgcccctgct agaaaaccaa ggcgaatcaa atcgctacga ctaatgtcaa actggctctc
    48301 atgttcaaat tgttctgtca cctgagctag agccgttttc aggtcttcat agctggcatg
    48361 ctcaattccc agagaacgcc ccttggtctt ggacttggga acagcttcat ctcgcttgag
    48421 aaaggcatgc tgaactgttg gaatgaccgt catgatcatg cgccgaatcc gttctccatt
    48481 aaaatctggg tctgtaaaga caatgactcc atgacgttgg tgcaggcgct gaatccgctc
    48541 tatatcctga tcattgatgg cagaacctcg agtctcatag gtctccacat cgaaataacg
    48601 cttgagattg accgtatcat cacgcccttc aaccacgata acttgagaaa ttttctcttt
    48661 cattacttgc tgtccagtcc aaaaattcgt tctgcatttg cagtcgttgc taccgccagc
    48721 tcttctgtcg tcataccacg caagtcagcg ataaagtcga ccacataacg agtataggct
    48781 gttttatttt cacgaccacg cttgggtaca ggtgctaagt aaggcgcatc tgtttccacc
    48841 aaaatcttgt ccaaaagtaa ctctttagct gcttcttgga ggtcagttgc cttcttaaaa
    48901 gtcaccactc ctgagaagga aatggtcata ccaagatcca caaacttctc tgcccactca
    48961 agcgtccctg aaaatgaatg catgatacca ccacgaggac caacgccctc actcttgata
    49021 atctcatagg tatcttccag cgcatcacgg gtatggacaa caaaaggcaa atccaagtcc
    49081 ttagatagct gaatctgacg gcgaaaaacc tgctcctgca cctctttggg cgctgtcatc
    49141 caatggtaat ctaagccaat ttcacctaaa gccacaacct tgggatgttt taacttatcc
    49201 aacaagtaag cctcaacttc ctctgtataa gtaccagctt ctgtaggatg ccaaccaata
    49261 gtcgcataga gctgatcata ctcatctacc aactccaagg cacgctcaat cgtcggttta
    49321 tcaaaaccaa caatattcat ctgtgtcaca cccatctcag cagccaaggc aatttcttct
    49381 gcctcacgac ctgcaaattc ttctacattc aagtgtgtat gtgtatcaaa aatcatctct
    49441 tctaacctcg ttttctatct tctattatac caaaaaagag gaggggcacc taatttttcg
    49501 gtttcccctc ctctcttcaa tagagagcta ttctgctatc ttttctatcc gatattgccc
    49561 atctcctatt ccacagttag agacagaaga gattggctac attgatagaa tattcctatt
    49621 cagctaaagt atgtgattat cttgggttct cacttttctc acccatcact aggattgatg
    49681 acttctcaaa atccccctta taatctaact ttaagtagag aatagaattt tctagctgtt
    49741 ctattttcta cgtctagtct ttcttcctag caaagcaaaa ccacttgttg ccaccactag
    49801 accaagacta gcaagtgctg cacttgatgc tgaacctgtg ttaggtaatt gtttgccagc
    49861 aggtgactgg taggtaacat cttgcattgt tcctgcagtt gcttgcggtg cacttgttgt
    49921 cttaggagca gcattaggag ccactggtct cttaggaact gtaaccatgg caatggcttg
    49981 cactccaatc gtttctgctt ccttcacatc ttccatagtt ttcgcatttt caatctcttt
    50041 gagagctgct tgtttttctg cttccactct tgctaaaagt tctgcttttt ctttatcaga
    50101 aagcggtgcg cctttgattt catcctgctt gtccttggct gctttttcaa tggcattttt
    50161 agctgattct ttttcagtag ctaattgctt agaagcttgt gattgagctg agttttgtga
    50221 acctgtgtga gctgatccac ccgcctggct accaccgcct tcattcgcat tagcatctga
    50281 gcttccagta ttgcctccct tatctccacc tggtgtattt tctagcttat actctggtgt
    50341 agcttcttga gttacagatt cacctttcgc agattgttga actgtatctt ttcctagaat
    50401 cgtcactact gaaccatctg ggaatgtgat tgttgctgta ccatctccag ctacttcaac
    50461 tttatagtaa aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta
    50521 acaatgtttt agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc
    50581 gaatccattt gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc
    50641 tactgatttt tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac
    50701 gacgagctgc caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt
    50761 tgcgcgcacg acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat
    50821 agattttgta ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt
    50881 ctatctgatt ctttcacttt tgtcaatagc cctaggcaaa tgtttccagc tttttcgaat
    50941 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
    51001 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
    51061 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
    51121 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
    51181 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
    51241 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag
    51301 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
    51361 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
    51421 ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
    51481 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
    51541 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
    51601 tcttaggata aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat
    51661 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac
    51721 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
    51781 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
    51841 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
    51901 tcagctggca atactgcatg atggccttac gggctgagaa aattcctttg gagtcagaat
    51961 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa
    52021 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
    52081 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
    52141 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
    52201 actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa
    52261 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
    52321 cataccaaaa gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa
    52381 catgaggaaa agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag
    52441 aaataagatt agatggtaga gtacatgaaa aactaaaaat ccaataaaac ttggataaag
    52501 aagcggtacc agactctcta attgacagat catgatcact tctaccaaga ctgaaactag
    52561 gataattcca taataaagga aatttgattt ttgaaaagag tttttcatca ttctcccttc
    52621 cttcacttct ttcctgctat cctttctttt attttatcat atatttatat agagtttaag
    52681 ccctaatatt cttttgaaaa atactttttt tgctttactt ctatagtgaa aaggtttaca
    52741 attatagtaa gaaaatttca ggaggtttca ttatggcaca acgttaccaa aatatcatgg
    52801 tcgcaatcga tggttctaag gaagcggact tggcttttgt caagggagtt cattctgctc
    52861 tacgaaacga cgctaaactc accatcgcac atgtcattga cacacgcgct ctccaaagcg
    52921 tatccacctt tgatgctgaa gtttacgaag aactccaagt cgacgctgaa agtctgatga
    52981 aagagtacga aaaacgtgct aaagatgctg gggtagcaga tgttcatatc gtcattgaaa
    53041 tgggaaatcc aaagaccctg ctagcacgta ctattccaga tgccgaggaa gtggacctca
    53101 tcctcgttgg cgcaactggt ctcaacgcct ttgaacgcct cttggtcggc tcttcatctg
    53161 aatacatact ccgccatgct aaggtcgatt tgctggttgt gagagaacaa gaaaaaacct
    53221 tataatcaca aagaaaagga gcccctagct cctttttgtt tacgatttat ttctctcttt
    53281 atggcgttcg taagccttga gctggcgctg cagttccttt ttaatagcag gttctggagc
    53341 atatttttct tcccaattat ctggttttaa gattttatgg gtcactggat caaaatgagc
    53401 cttgccatct ggaaaaattt tccccatatt ggcctgatgg acaatatcaa aaatacgttc
    53461 tgggtccacc cccatcaaga caaaactgcc gtaggtgaag taaagcgtgt caatcaaggc
    53521 atccacttgc cctatcaaat cttgctgagc aggtgtcttc ttggctactt tatctgctgc
    53581 cttatcaagg gcctgatgaa gttgcgatac agcttgacca aaatcttctt cagaaggact
    53641 ggctgctcga acaaactcca ccaattcttc tattttaaaa ccagccctat gggttgcacc
    53701 ctctaaatcc caagctcgag gttcttcttg ggttcgttca tccatcatgt ggtggaaggt
    53761 cttgacctta ttgaaatgat agtcacggct gacaaagact ttttctgaag acaaaacacc
    53821 aaaatgttcc aaggccttgt ggatcccatc ttgttgattg ctagtggtaa tgtgcttggc
    53881 agcttccttg acactgctac taccatttcc catagcgacc gacataccga cgccagccag
    53941 catttcaagg tcattatctg agtcaccaaa agccatgact tgattgaggt caaagccata
    54001 ttctttccca actcggcgaa tgccttctaa tttagaattt ccctgattga tgacatccga
    54061 tgcaaaagga ttgctacgtg tcaatttcaa gtcttcaaaa tcagctgccg ccttctcaga
    54121 ttcttctggt gtcatcagca tcaaaacttg gtagataggc tgattcatca ggtgaagcag
    54181 gtcctcttcc ttttggggaa caaccttgct gaccatgcga ttaaaagact gactcaccgt
    54241 ccgagttaaa acagagggaa cgaagcgact aattcgttgg gaaaaagaac ccagaccaaa
    54301 ggacatgatt ttagaaccca acatggcatc cttggtccct agggcaatct ccgtgccctc
    54361 ttttttagca tagctaatta gatggcgcaa atgtaacttg gaaatagggc tcgtgaacaa
    54421 gactctgtct ttactaaaga tatactggcc attataggtt accgcaaaat ccagatccaa
    54481 atcgtccatc aattccttaa caaaaaaagg tcctcgccct gtcgctacgc caactagtac
    54541 cccttgttct ttgacaatct taatcgcatc cttagtggat ttcaaaacac tcttgcgatt
    54601 gttgaccaag gttccatcga tatcaaaaaa aacagctttg acttccatcc tatcccaatc
    54661 tccccttttg tgatacaatg attataccac atttcagaaa gagttagtaa atcatgccta
    54721 agaaaatcct tgttttacat acgggtggaa ctatttccat gcaggccgat gcttctggcg
    54781 ctgttgtgac gagttcagat aatcccatga accatgtgtc caacccactt gaaggaatcc
    54841 aagtccacgc cttggacttt tttaaccttc caagtcccca tatcaaaccc aaacatatgc
    54901 tggtcctcta ccagaaaatt aaagaggaag cagataacta cgatggagtg gtgatcacac
    54961 acggaaccga tactttagag gaaacagcct atttccttga taccatggaa gttccccaca
    55021 tgcctatcgt tctaacagga gccatgcgta gctccaatga gctcggtagt gatggtgttt
    55081 ataattacct aagtgcttta cgagtggcca gtgatgacag ggctgctgac aaaggagttt
    55141 tggtcgttat gaacgatgaa atccacgctg ccaagtatgt caccaaaaca catacgacta
    55201 atgtcaacac cttccagact ccaacacatg gccccctcgg tctcatcatg aaacaggaaa
    55261 tcctctactt caaaacagct gaacctcgtg ttcgctttga ccttgatcac atacaaggtt
    55321 tagtccctat catctcggct tatgctggta tgacagatga gctgattgat atgctggatt
    55381 tagaacactt ggacggtttg attatccaag ccttcggagc tggtaatatt cccaaagaaa
    55441 cggctcaaaa attagaaagc cttctgcaaa aaggaatccc agtcgctctg gtatcacgat
    55501 gctttaacgg tattgccgag cctgtttatg cctaccaggg tgggggcgta cagttgcaaa
    55561 aagcaggcgt tttctttgtt aaagaactca acgcccaaaa agcccgcttg aaactcctca
    55621 tcgccctcaa tgccggacta acaggacagg ctttgaaaga ctatatggaa ggctaatact
    55681 cttcgaaaat ctctgcaaac cacgtcacgt cgccttaccg tatgtatggt tactgacttc
    55741 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag ttctatctgc
    55801 aacctcaaag cagtgctttg agctgacttc gtcagttcta tctacaacct caaaacagtg
    55861 tgttgcgcag cctttaacca gccgcctagt ccgctctatg gtattcatta agtcaacatc
    55921 tcttgtttaa gagcacaaaa tcaggaaatc ttctcgattc cctgattttt tctatttacg
    55981 ttttcgtgtt gagctacgtt ctgtcaaacc atgaggtaag agaacttcac gttcttccaa
    56041 ctcttcctta tgcataatct tggtcaacat acgcatacta atggcaccaa ggtcataaag
    56101 aggttgggca atcgttgtca agtttggacg ggtaaagcgt gagatttgtg aatcatcact
    56161 agtaataatt tcaaaatctt ctggcacaga aacaccctta tcagccaaac cgttcaagac
    56221 tcctgctgcc aactcatcac ctgtcacaac tgctgcagtt gcatttgatg aaatcaaacg
    56281 ctctgctaag gcgtaaccat catcatagct atatttagat tcaaatacca aaccctcact
    56341 ataagcgatt cctgcttttt tcaaggtttc cttgtagcca actaaacgaa ccttaccatt
    56401 gatgtcatcc actaacggac cgctaacgaa agcaatacgc tcattttctt tagcaaggta
    56461 actcactgca tcaattgttg cttgcttata gtcaatattg acacttggca actggtgctc
    56521 aacatcgaca gttcctgcga gaacaatcgg agtacgtgaa cgcgaaaatt ctgagcgaat
    56581 tttatctgtc aagtgataac ccatatagat aatgccatct acctgctttg aaaagagggt
    56641 attgacaaca gaaacttctt tctcgttatc ttcatcgcta ttagctagga caatattgta
    56701 cttgtacatt tctgcaatat catcaatccc cttagccaaa ctcgaaaaat aaccattggt
    56761 aatatttgga atcacgacac cgacagtggt tgtcttttta cttgcaagac cacgcgcaac
    56821 tgcatttgga cgataatcca agcgatcaat tacctctagc acttttttac gggtattctc
    56881 ttttacattt ttattgccat tgaccacacg gctgaccgtc gccatggaaa cacctgcttc
    56941 acgagcgaca tcataaatgg ttactgtatc atctgcattc attccttttc ctgtcctttc
    57001 tatctcacac attcttttac aagtagaggt actgattgaa gctctatatc tacttacaaa
    57061 agtgaagatg tgaaaatttc gttttcatat ttctacttat tccattctat cactaattgt
    57121 aaacactttc aagtgttttt tgaagattga ttgaaaaaat ttcatagaaa acctaggttt
    57181 agctccttgc taccacctta gactaaacaa aacggaggaa actaagccct cctaaagtta
    57241 tagtaaaatg aaataagaac aggataaatc gatcaggaca gtcaaatcga tttctaacaa
    57301 tgttttagaa gtagaggtgt actattctag tttcaatcta ctataggtat tgttccattc
    57361 actaccgtca attttagcac atagtcttca tgaaaatatt atatcatcat aaccaaccag
    57421 attcttttgc gatattagct gcctctgttc gattaccagc atccaatttt gaaagaatat
    57481 tggtgacata gtttcgaata gttccgtttg agaggtaaag ctgatctgcg atttcttggt
    57541 tggataagcc ccgggcgatc ccctttaaga cagcaatctc ttgttctgtc aacggattgg
    57601 gacgggtcat caccacttcc atcaattcag gcgaatactc cttgcgtcct tcgaggacgg
    57661 tgtgcaaggt ttgcatgagg tctgcaacgc ttcgttcctt taatacataa gcatccactc
    57721 cagccttgac cgcacgttca aaatacccag cacgcttgaa ggtcgtcacc acaaccacct
    57781 ttgtttcaag cctttctgat cgtatccact ccaagacttc aagacctgtc ttaacaggca
    57841 tttctacgtc aaggatggcg atatctacag actccttttc taatagttgg attgcttctt
    57901 gcccattctt ggcttgaagg acagactcca catctggttg aagcgtgagc aattgacaca
    57961 tggcatctcg caacatactt tgatcttctg cgactaatac tttcatctta gtttctctcc
    58021 ttataaggta gtcgaacttg cacttccgtt ggatgtttct gactgattac acttacttct
    58081 cctgaaaatg gaaaaacacg atctcggatt gtatggagct catctccttt tagaaaagca
    58141 aagccgcagc catcatcact tactgttaaa atgagttcct tctctgtccg ttctaatttt
    58201 aagtaagctt tagacgcttt ggcatgtttg atgatattgg tcaccaactc aagcaaaatc
    58261 atagaagcca ttgactccaa ttcttgagta aggctagcag tatctagttg gttatctgtt
    58321 tccacctcaa ttccagcaat ttctaacatc tttttcacag tctctagttc ggatgtcaaa
    58381 gttctagact taagattttc cacaatggtt cgaacttcac gcattgattc tttgctaatt
    58441 tgctgtattt ctcttaattc cttttccact tgtggataag cctgcatttg aaatagctgc
    58501 aaggctagat ctatcttgac actaagcata gcaaaggtat gtcccagact atcatgcaaa
    58561 tcctgaccga tacgattgcg ctcattttct gctagcaata gatttatctg ggtattttgc
    58621 ttgacctgag cttctttcaa atcctcgaca aggcgaattc gaaccgagcc caaagtcatc
    58681 aaatcgacaa aagtaagaat tacaagcata tagactagaa actcaacttc gattctctga
    58741 aaaatcaaaa gtcgccccac aacaaggact tgagcaagga gaaatgtcca tacatgtaaa
    58801 gactttaaac tacgtacgcc aaaatgataa attaagagat tggaaaggaa aaagaaaaac
    58861 cagatataat tcccagcaac aaaggcggta ttcccagcta catagaccag catgagcccc
    58921 cagaaaagcc aagataggcg ctggttctta gttattaaaa cacccaaata cgtcactaca
    58981 aatagaatat caaccaataa atgccaagca ggaagctccc caatcactac aggtaggatg
    59041 ggaaaaagca taaaaatcaa actggcccaa aacatatagt gtatgctttt cagtctttca
    59101 agcattaagc attctcctta tgaccttgaa ggtaaatagt caaaccaaat aaaactgctg
    59161 aaaaaacaag taaataaact gtggctgata gattgatgcc accctcgttt aagaaggtct
    59221 tgagcaactc catcaattga taggtcggga gacacttacc aactgcttgc atccagtctg
    59281 gaaataaaga aatgggcatc cagagtccgc ctaaaacagc caatcctaga taaagaagat
    59341 tgcccacaac agacatcagc tgactagttg gtaagagagt caaggtcaag ccaagtgcta
    59401 caaaagcaat actccccaca atcagcaaaa tcgcagctcc aacccatttt actagaggca
    59461 tgtctacacc tcttacaaaa tgtccaactg taaaaacaac cagaattgag accaaataat
    59521 caaccagcat acttgttatc tttgatagat aatattctac catatttaca gggctatgac
    59581 gcaatgtttt ctgccagttg ttcatcttat cggtatgtaa aacagctgga aatgagagga
    59641 tagttgtcga catcatggaa aaggcagtca tggaaatgag gtaatcacgc ataaaattcg
    59701 cgagttcacc tggtgtgtcc tgatagatac cagaaaaaaa taaatagaaa gccgtcggca
    59761 tccctaccga caatagataa tagattaatt gtcgtttggt caataaaaat tctatcttac
    59821 taagtgctat ccatcgtttc atcttagtta tctcccttct gcgtctcttc aaagattgta
    59881 ttcaacaaac tacgattatt aacttcgatt tcttgcatcc tacatcctgc ttgggctaat
    59941 agttcccaga aagcatctgc ttctcgagtg actacttgta aagaatcttg ctttagggtc
    60001 cagttttcaa ccaaatttga ctgctctacg acttccttgt aagctatagg aaggataaag
    60061 tgcttttcta tttcctcgct acgcatagct agaggcgtcg tatctcgaat caactctccc
    60121 ttatttaaga gcaaaatgcg gtctgcagtg tgttccactt cctcaatata atgggacgaa
    60181 tagagaatgg tgactccttg cgcttttaac tcctggacaa tttcccaaaa acgttgacga
    60241 gttgaggtat ccatggacgc agtaggctca tctaaaaaaa caatctttgg tcgcccaatt
    60301 aaggtcaaga cgaaagaaaa gagacgcttt tgaccgcctg ataatttttc tgccaactgt
    60361 tctttttgtt gcttgacaaa ctgcaatagt tgatcaattt cctgattgct caaaggattt
    60421 ggatagatac gttgaaagaa agcaatcaac tctttaactt ttaatttctg aacgattaca
    60481 ttttcttgag ggaggtaagc cctagtatag tctaacttag aactcgtcac tggtaaacct
    60541 tgaatagata cttgaccgct tgtgaccagt ttatctccaa gcaaacaatc taagagtgtt
    60601 gtctttccgg caccatttgg accaattaag gcaacacatt caccatcgtt gatttcaaag
    60661 gagatattcc gcaaaatttc cttgtctttt attttcttac tcaatttctc aactttaacc
    60721 accgtcatga gactctcctt tcaaccactc cattcccata aggaaaacga cgaaaatcat
    60781 aaatccaaac cccaaagcac cacgaatgaa ttggcgaagc aaggcttgat caaaccaatc
    60841 agtaaacatt tccactaacc ataccaagag tgacaggccg ataaagaaat agatgatccc
    60901 tctcttcatt cctcaaactc ctttttcaca tctctgacta atttcaaacc ttctctaaca
    60961 agccaagaca tgattccaaa gccagcaaag accttccaag gaaaatggta gaaatcctca
    61021 tccaatcccg aaaacatgag ataggtcata actcctgcta ctactaaact tactgcgata
    61081 atcattttat ttctcatctc ttcttccccc atttcatact acaattatag tcttttaaaa
    61141 tcagaggaga cagaagcttc tgtcactaga aaatatgaca aatgtcataa aaaattctgt
    61201 tcaaaacaag caagatacac tatacaataa aacacaatca gaaaaatcta aggcaacttc
    61261 ctcaaaagag atatcaaacc caattcacac cataatgtaa actaatactt atttaaaatc
    61321 aaaaagagta aaaattttta tcagacaaac acatatatag tgtattgaat ctataacagt
    61381 aggccttaaa tactaaaata tttctataaa ttaatttaac tttcctgata gaactgttca
    61441 tatcttattt caattctcta tattatacgt tgaaccaaac ccttctattg ctttcttaaa
    61501 aatttataag agttataaaa tctgttaaat ttcaatgtgt atatctaaac tacggtattt
    61561 attgaaaaga ctggagacaa aaagtatacg ctgccaaaat gaattactga aaatcaaaaa
    61621 agagagaacc aaactgattc cctcttaatg tatataatat ctagttttaa aaatacacac
    61681 tcacatatct ctgt
//
LOCUS       DAVMCN010000007        55684 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVMCN010000007 DAVMCN010000000
VERSION     DAVMCN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.007"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            330..1022
                     /locus_tag="VYP85_000553"
                     /pseudo
     CDS             330..1022
                     /locus_tag="VYP85_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            1076..1465
                     /locus_tag="VYP85_000554"
     CDS             1076..1465
                     /locus_tag="VYP85_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1881105.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(2126..3154)
                     /gene="queA"
                     /locus_tag="VYP85_000555"
     CDS             complement(2126..3154)
                     /gene="queA"
                     /locus_tag="VYP85_000555"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1881106.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            3305..4012
                     /locus_tag="VYP85_000556"
     CDS             3305..4012
                     /locus_tag="VYP85_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1881107.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            4152..4328
                     /locus_tag="VYP85_000557"
     CDS             4152..4328
                     /locus_tag="VYP85_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1881108.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            4458..5393
                     /locus_tag="VYP85_000558"
     CDS             4458..5393
                     /locus_tag="VYP85_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1881109.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            5386..6174
                     /locus_tag="VYP85_000559"
     CDS             5386..6174
                     /locus_tag="VYP85_000559"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1881110.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            6175..6558
                     /locus_tag="VYP85_000560"
     CDS             6175..6558
                     /locus_tag="VYP85_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1881111.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            6574..6963
                     /locus_tag="VYP85_000561"
     CDS             6574..6963
                     /locus_tag="VYP85_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1881112.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            7047..8177
                     /locus_tag="VYP85_000562"
     CDS             7047..8177
                     /locus_tag="VYP85_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1881113.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLNAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            8182..8919
                     /locus_tag="VYP85_000563"
     CDS             8182..8919
                     /locus_tag="VYP85_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1881114.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            8930..9703
                     /locus_tag="VYP85_000564"
     CDS             8930..9703
                     /locus_tag="VYP85_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1881115.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEYKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            9693..10310
                     /locus_tag="VYP85_000565"
     CDS             9693..10310
                     /locus_tag="VYP85_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1881116.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            10520..10921
                     /locus_tag="VYP85_000566"
     CDS             10520..10921
                     /locus_tag="VYP85_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1881117.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            10921..11199
                     /locus_tag="VYP85_000567"
     CDS             10921..11199
                     /locus_tag="VYP85_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1881118.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            11189..11962
                     /locus_tag="VYP85_000568"
     CDS             11189..11962
                     /locus_tag="VYP85_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1881119.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            11963..13267
                     /locus_tag="VYP85_000569"
     CDS             11963..13267
                     /locus_tag="VYP85_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1881120.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            13841..14719
                     /gene="pstS"
                     /locus_tag="VYP85_000570"
     CDS             13841..14719
                     /gene="pstS"
                     /locus_tag="VYP85_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1881121.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            14719..15636
                     /gene="pstC"
                     /locus_tag="VYP85_000571"
     CDS             14719..15636
                     /gene="pstC"
                     /locus_tag="VYP85_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1881122.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            15626..16510
                     /gene="pstA"
                     /locus_tag="VYP85_000572"
     CDS             15626..16510
                     /gene="pstA"
                     /locus_tag="VYP85_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1881123.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            16521..17324
                     /gene="pstB"
                     /locus_tag="VYP85_000573"
     CDS             16521..17324
                     /gene="pstB"
                     /locus_tag="VYP85_000573"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1881124.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            17337..18095
                     /gene="pstB"
                     /locus_tag="VYP85_000574"
     CDS             17337..18095
                     /gene="pstB"
                     /locus_tag="VYP85_000574"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1881125.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            18107..18760
                     /gene="phoU"
                     /locus_tag="VYP85_000575"
     CDS             18107..18760
                     /gene="phoU"
                     /locus_tag="VYP85_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1881126.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            18917..19732
                     /locus_tag="VYP85_000576"
     CDS             18917..19732
                     /locus_tag="VYP85_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1881127.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(19752..21023)
                     /locus_tag="VYP85_000577"
     CDS             complement(19752..21023)
                     /locus_tag="VYP85_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1881128.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            21165..21896
                     /gene="budA"
                     /locus_tag="VYP85_000578"
     CDS             21165..21896
                     /gene="budA"
                     /locus_tag="VYP85_000578"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1881129.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            21906..22097
                     /locus_tag="VYP85_000579"
     CDS             21906..22097
                     /locus_tag="VYP85_000579"
                     /inference="COORDINATES: protein motif:HMM:NF021592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1881130.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKRR"
     gene            22132..22659
                     /locus_tag="VYP85_000580"
     CDS             22132..22659
                     /locus_tag="VYP85_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1881131.1"
                     /translation="MIYGLAMAAFFEETARLVFFKWLEKKRSLEKADALAYGLGHGGL
                     ELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQSLSVWQIYLLGFERILAL
                     GFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQVGWLTNPVLVEVILALEL
                     VLVAYGTKEIFCKKS"
     gene            22771..23721
                     /gene="murB"
                     /locus_tag="VYP85_000581"
     CDS             22771..23721
                     /gene="murB"
                     /locus_tag="VYP85_000581"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1881132.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            23780..24937
                     /locus_tag="VYP85_000582"
     CDS             23780..24937
                     /locus_tag="VYP85_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881133.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            24918..25724
                     /locus_tag="VYP85_000583"
     CDS             24918..25724
                     /locus_tag="VYP85_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881134.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            25721..26494
                     /locus_tag="VYP85_000584"
     CDS             25721..26494
                     /locus_tag="VYP85_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881135.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVSYYFISREKEEQA"
     gene            26491..27561
                     /locus_tag="VYP85_000585"
     CDS             26491..27561
                     /locus_tag="VYP85_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1881136.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            27806..28045
                     /locus_tag="VYP85_000586"
     CDS             27806..28045
                     /locus_tag="VYP85_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881137.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            28320..28805
                     /locus_tag="VYP85_000587"
     CDS             28320..28805
                     /locus_tag="VYP85_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1881138.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEILESQS
                     H"
     gene            28827..31445
                     /gene="alaS"
                     /locus_tag="VYP85_000588"
     CDS             28827..31445
                     /gene="alaS"
                     /locus_tag="VYP85_000588"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1881139.1"
                     /translation="MKQLSSAQVRQMWLDFWSTKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31535..32989)
                     /locus_tag="VYP85_000589"
     CDS             complement(31535..32989)
                     /locus_tag="VYP85_000589"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1881140.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            33168..33917
                     /locus_tag="VYP85_000590"
     CDS             33168..33917
                     /locus_tag="VYP85_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881141.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            33898..35532
                     /locus_tag="VYP85_000591"
     CDS             33898..35532
                     /locus_tag="VYP85_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881142.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVIAFSTSLTAFYNVFYESK
                     DLVSYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIALTVFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENLDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            36217..37380
                     /locus_tag="VYP85_000592"
     CDS             36217..37380
                     /locus_tag="VYP85_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1881143.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            37377..38054
                     /locus_tag="VYP85_000593"
     CDS             37377..38054
                     /locus_tag="VYP85_000593"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1881144.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLNFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            38044..38898
                     /locus_tag="VYP85_000594"
     CDS             38044..38898
                     /locus_tag="VYP85_000594"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1881145.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNAAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQDQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            38917..39984
                     /locus_tag="VYP85_000595"
     CDS             38917..39984
                     /locus_tag="VYP85_000595"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1881146.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            39994..41160
                     /gene="aroC"
                     /locus_tag="VYP85_000596"
     CDS             39994..41160
                     /gene="aroC"
                     /locus_tag="VYP85_000596"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1881147.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            41170..42273
                     /locus_tag="VYP85_000597"
     CDS             41170..42273
                     /locus_tag="VYP85_000597"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1881148.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            42284..42622
                     /locus_tag="VYP85_000598"
     CDS             42284..42622
                     /locus_tag="VYP85_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1881149.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            42714..43997
                     /gene="aroA"
                     /locus_tag="VYP85_000599"
     CDS             42714..43997
                     /gene="aroA"
                     /locus_tag="VYP85_000599"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1881150.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            43990..44466
                     /locus_tag="VYP85_000600"
     CDS             43990..44466
                     /locus_tag="VYP85_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1881151.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            44463..45311
                     /gene="pheA"
                     /locus_tag="VYP85_000601"
     CDS             44463..45311
                     /gene="pheA"
                     /locus_tag="VYP85_000601"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1881152.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGTYPIYPISD
                     HGKERR"
     gene            45308..46582
                     /gene="psr"
                     /locus_tag="VYP85_000602"
     CDS             45308..46582
                     /gene="psr"
                     /locus_tag="VYP85_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1881153.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            46861..47706
                     /locus_tag="VYP85_000603"
     CDS             46861..47706
                     /locus_tag="VYP85_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1881154.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EYNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            47696..48799
                     /locus_tag="VYP85_000604"
     CDS             47696..48799
                     /locus_tag="VYP85_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1881155.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEEFLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            48801..49787
                     /locus_tag="VYP85_000605"
     CDS             48801..49787
                     /locus_tag="VYP85_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1881156.1"
                     /translation="METALISVIVPVYNVAQYLEKSIDSIQKQTYQNLEIILVVDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSADQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            49803..51236
                     /locus_tag="VYP85_000606"
     CDS             49803..51236
                     /locus_tag="VYP85_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1881157.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            51265..52299
                     /locus_tag="VYP85_000607"
     CDS             51265..52299
                     /locus_tag="VYP85_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1881158.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            52499..53236
                     /gene="mecA"
                     /locus_tag="VYP85_000608"
     CDS             52499..53236
                     /gene="mecA"
                     /locus_tag="VYP85_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1881159.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            53387..54673
                     /locus_tag="VYP85_000609"
     CDS             53387..54673
                     /locus_tag="VYP85_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1881160.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            54675..55544
                     /locus_tag="VYP85_000610"
     CDS             54675..55544
                     /locus_tag="VYP85_000610"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1881161.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
BASE COUNT        16107 a        10369 c        12677 g        16531 t
ORIGIN      
        1 tgtgtaagga atgatgaaag atgagtgaaa attatcaagt tggaatgttt gtatctaaat
       61 atattagcat gtatttagat cagatgtctg caatccttta tatatgagat tgattacgat
      121 atagttaaag tgttagttca atagtaaata tatcattcta agtctatttt atatataaag
      181 tatattgttt aacgtttgat agaaaagatg ctatactaga agtaggatgt aatggcaaaa
      241 tctaatacta ataagcgcta tgcaatacgt aaactcggaa agatttttgg ttctgcggta
      301 atcgggctaa ctttattttt aggaggaatc tgaatacaag ttttgctcat gctgctgatg
      361 ggattcaata tgtcagagat gatactagag ataaagaaga gggaatagag tatgatgacg
      421 ctgacaatgg ggatattatt gtaaaagtag cgactaaacc taaggtagta accaagaaaa
      481 tttcaagtac gcgaattcgt tttgaaaaag atgaaacaaa ataccgtagt gaaaatcctg
      541 ttacaattga cggagaggat ggctatgtaa ccacgacaag gacctacgat gttaatctag
      601 agactggtca tgttaccgaa caggttactg ttgatagaaa agaagccacg gatacagtta
      661 tcaaagttcc agctgaaagc aaggttgaag aagttcttgt tccatgtgct actaaatatg
      721 aagcagacaa tgacctttct gcaggacagg agcaagagat tactctagga aagaatggga
      781 aaacagttac aacgataact tataatgtag atggaaagag tggacaagta actgagagta
      841 ctttaagtca aaaaaaagac tctcaaacaa gagttgttaa aaaatgaacc aagccccaag
      901 ttcttgtcca agaaattcca atcgaaacag aatatctcga tggcccaact cttgataaaa
      961 gtcaagaagt agaagaagta ggagaaattg gtaaattact cttactacaa tctatactgt
     1021 agatgaacgt gatggaacaa ttgaagaaac tacttctcgt caaattacta aagagatggt
     1081 aaaaagacgt ataaggagag ggacgagaga acctgaaaaa gttgttgttc ctgagcaatc
     1141 atctattcct tcgtatcctg tatctgttac atctaaccaa ggaacagatg tagcagtaga
     1201 accagctaaa gcagttgctc caacaacaga ctggaaacaa gaaaatggta tgtggtattt
     1261 ttataatact gatggttcca tggcaacagg ttgggtacaa gttaatggtt catggtacta
     1321 cctcaacagc aacggttcta tgaaagtcaa tcaatggttc caagttggtg gtaaatggta
     1381 ttatgtaaat gcatcgggtg agttagcagt caatacaagt atagatggct atagagtcaa
     1441 tgataatggt gaatgggtgc gttaacagat tcctccctgc gacaaaattg ataatagtat
     1501 gtctgaatat ataattatat ataaaaagct atagataagg tcatcttata gcgactataa
     1561 aaaagtgaac aagcctagtc ttctgtacat tagaattcag atttgttcac tttttgttta
     1621 atactcaatg aaaatcaaag agcaaactag aaaactagtc gcaggttgct caaagtactg
     1681 ctttgaggtt gtagatagaa ctgacgaagt cagtcacata tataatccaa ggtgacgttg
     1741 acgcggtttg aagagatttt tgaagagtat aagtctttga ttttgagact aaggagagtc
     1801 agggtcaaag tagtgaatga ttctgaaata actcataata gtctcttgag aggacagata
     1861 agagtaacaa atatggtgct actcatgtgt cttgcatttt gatttacaaa cagcgaagaa
     1921 aatataggaa gctgaaataa aatatagatg aatcaatttg gagagtcaac gcaatctatg
     1981 gcaatatttt cgaagctagg gggaagcatt ttaatttcaa tgtactaggc gtcttctaca
     2041 gctagctaga gtttcaattg tagatgttct ttgaaataat atcttagcga tttattggta
     2101 ttagaagaat tagagaaatt ctttctcaat aaataaacat ggcgtcacca aaactgaaga
     2161 agcggtagtg ttcttggatg gcatggtggt aggcatctaa gactaattca cggcctgcaa
     2221 aggcagaaac caacatgacc agagttgatt ttggcagatg gaagttggtt gagaaggcat
     2281 ccacgacctt ccactcatac ccaggtttga taaagatatt ggtccaacca gaatctgctt
     2341 ggatttgccc atcaaacttg gaaccaatag tttccaaggt gcggatagaa gtggttccga
     2401 cagcgatgac gcgaccacca ttttctttga cagagcgaag ggtggcagca gcttcctcag
     2461 aaagttgata gaactctgag tgcatttcgt gttcgtccag attatccaca gaaacaggtc
     2521 taaaggttcc gagtccgaca tggagagtca gatagactag atgaacaccc ttagcttgga
     2581 tttctgccag cagttctttg gtgaagtgaa gaccagcagt cggtgctgca gcagagccgc
     2641 tttccttggc gtagacggtt tgataacgtt cacggtcatc taatttttcg tggatataag
     2701 gtggcagagg catttctccc agactttcca agacttctag gaaaattcct tggtattcaa
     2761 agcggacaat gcgtcccccg tgggtcaatt cttctgtaac gacagcgctg aggcggccat
     2821 caccaaagct gatacgagta ccgaccttga ggcgtttggc aggtttagcc agaacttccc
     2881 actcgtctcc actagtgttc ttaaggagga gaagttccac atgacctcct gtctccactt
     2941 tttgaccata gaggcgggca gggagaactc gggtgtcgtt catgacaagg gcatcaccag
     3001 gttccagcat atcaataata gagtggaaat gtttatcttg catttctcct gtctcacggt
     3061 tgacgatgag gagtttggag gcatcacgtt tttcaagggg cgtttgggca atcaattcct
     3121 ctggcaagtg gaaatcaaaa tcagctgtat tcatatattt gttcattctt tctaagttct
     3181 aatcctatcc attataacac gtttcaagtt tggacgctct ttttttagaa attaaatcgt
     3241 tttcacttga caaaaattgg tctataccat ataataaata tagacagaaa tggaggatga
     3301 aaagatgaaa gttattaaag ttgaaaacca agttcaaggt ggaaaagttg cttttgagat
     3361 tttgaaggaa aaattggcta atggagctca aactctagga cttgcgacag gaagtagccc
     3421 acttgaattt tacaaggaaa ttgttgagag tgaccttgat ttttcaaatc taaccagtgt
     3481 caaccttgat gagtatgtgg gccttgatgg ggacaatcca cagtcttatc gttacttcat
     3541 gcaagaaaac ttgttcaacc aaaaaccatt taaagaaagt ttcttgcctc gtggtgttaa
     3601 ggacaatgct gaagctgaag ttgaacgcta caaccaaatt ttggctgacc atccagttga
     3661 cctccaaatc ttgggaatcg gtcgcaatgg gcatatcggc tttaatgagc ctggtactcc
     3721 atttgacagt caaacgcatc tagtagaact tgaccagtct actatcgaag ccaatgcacg
     3781 cttctttgcc aagattgaag acgtcccaac ccaagctatt tcaatgggga ttaaaaacat
     3841 tttggatgcc aagtctatta ttctttttgc ttacggtgag tcgaaagcag aagccattgc
     3901 cggaacagta tctggcccag tgactgagaa cctacctgca agtagcctcc aaaatcaccc
     3961 tgatgtaacc atcatcgcag atgctgaagc gcttagctta ctcgaaaaat aaaaaagcaa
     4021 tgttctattg aacgctttca actcttgtat aaatggaaga aaaaatcaaa attaaaccgc
     4081 atttttgctt gacaattatt ccttttacgt gtagaatgaa atagatcttg aacttgaagg
     4141 gagtgaaaaa aatgtctaaa acagtagtac gtaagaatga atctcttgac gacgcacttc
     4201 gccgtttcaa acgtgcggtt actaaagctg gtactcttca agaaacacgc aaacgtgaat
     4261 tctatgaaaa accttctgta aaacgtaaac gtaaatcaga agtagctcgt aaacgtaaaa
     4321 aattctaatt gaaatgaaag gctagagaaa tctagtcctt tttcttttaa ataaatactc
     4381 caaagcctgc aaaaatctga aacttcctcc tacaatttga tataatagag agaagaactc
     4441 atttgaagga ggaaatgatg tcggttttag taaaagaagt gattgaaaag cttagactag
     4501 acattgtcta tggtgaacca gaattgcttg aaaaggaaat caatacagcg gatattacgc
     4561 gacctggtct tgaaatgaca ggctattttg actactatac accagagcgg attcaacttt
     4621 tggggatgaa ggagtggtct tatctgatca gcatgccttc caacagccgt tatgaagttt
     4681 tgaaaaaaat gtttctacct gagacaccag cagtcattgt tgcccgtggt ttggtggttc
     4741 cagaggagat gttaaaggct gctagagaat gtaagattgc tattttaacc agccgtgcag
     4801 ctaccagtcg tttatctgga gagttatcta gctatctgga ttctcgtttg gcagaacgta
     4861 ccagtgtgca cggtgtcttg atggatattt atgggatggg cgtcttgatt cagggagata
     4921 gtggaattgg taagagcgag acaggtcttg agcttgtcaa acgtggtcac cgtttggtag
     4981 ccgatgaccg tgtcgatatc tttgccaagg atgagattac tctctggggt gaaccggctg
     5041 aaattttgaa acacttgatt gaaattcgtg gggttggtat tatcgatgtt atgagtctct
     5101 acggtgcgag tgctgtcaag gattcttcac aggttcagct tgctgtctat ttggaaaatt
     5161 acgatacgca taagaccttt gatcgtcttg gaaacaatgc agaggaactt gaagtttctg
     5221 gcgtagccat tcctcgtatt cgtattccag ttaaaacagg tcgtaatatc tctgttgtga
     5281 ttgaggcagc tgccatgaat tatcgtgcca aggaaatggg ctttgatgct acccgtttgt
     5341 tcgacgaacg actgacaagt ctcatagctc gaaatgaggt gcaaaatgct tgatccaatt
     5401 gctattcaac taggacccct agccattcgt tggtatgcct tatgtattgt gacaggcttg
     5461 attcttgcgg tttatttgac catgaaagaa gcacctagaa agaagatcat accagacgat
     5521 attttagatt ttatcttagt agcctttccc ttggctattt taggagctcg tctctactat
     5581 gttattttcc gatttgatta ctatagtcag aatttaggag agatttttgc catttggaat
     5641 ggtggtttgg ccatttacgg tggtttgata actggggctc ttgtgctcta tatctttgct
     5701 gaccgtaaac tcatcaatac ttgggatttt ctagatattg cggcgcctag cgttatgatt
     5761 gctcaaagtt tggggcgttg gggtaatttc tttaaccaag aagcttatgg tgcaacagtg
     5821 gataatctgg attatctacc tggctttatc cgtgaccaga tgtatattga ggggagctac
     5881 cgtcaaccga ctttccttta tgagtctcta tggaatctgc ttggctttgc cttgattctg
     5941 atttttagac ggaaatggaa gagtctcaga cgaggtcata tcacggcctt ttacttgatt
     6001 tggtatggtt tcggtcgtat ggtcatcgaa ggtatgcgaa cagatagtct catgttcttc
     6061 ggccttcgag tgtcccaatg gctgtcagtt gtccttatcg gtctcggtat aatgatcgtt
     6121 atttatcaaa atcgaaagaa ggccccttac tatattacag aggaggaaaa ctaaatgtta
     6181 gaagttgcat atattcttgt tgccctagct ttaattgtct ttttggtcta tctgatcatt
     6241 actgtacaaa agcttggtcg tgtcatcgat gaaacagaaa agacgattaa aaccttgact
     6301 tcagatgtgg atgtgacctt gcatcacacc aatgagttgt tggctaaggt caatgtcttg
     6361 gcagatgata tcaatgtcaa ggtggctacg attgatccac tcttcagtgc tgttgcagat
     6421 ttatctctat ctgtttcaga cctcaatgac catgcgcgtg tcttgagcaa gaaagcttca
     6481 tcagctggtt caaaaacact caagactggt gcaagtctgt cagctcttcg tcttgcaagt
     6541 aaatttttca aaaaataaaa aaggagaatc cttatgggta aattatcctc aatcctttta
     6601 ggaacggttt caggtgcagc tcttgccttg tttttaacaa gtgataaggg caaacaagtt
     6661 tgcagtcagg ctcaagattt tctagatgat ttgagagaag atccggagta tgccaaggag
     6721 caagtctgtg aaaaactgac agaagttaag gagcaggcta cagattttgt tctgaaaaca
     6781 aaagaacagg ttgagtcagg tgaaatcact gtggacagta tacttgctca agctaaatcc
     6841 tatgcttttc aagcgacaga agcatcaaaa aatcaattaa ataatctcaa ggaacaatgg
     6901 caagaaaaag ccgaagctct tgatgactca gaagagattg tgattgatat aacagaagaa
     6961 taaaccatca ccatctccgg acggactatg tatctgggga tggtgatttt tatctggaat
     7021 ctagtctttg tggtataata attactatgc agaaaaaacc aacgtcagcc tatgtgcaca
     7081 tcccattttg tacccagatt tgttattatt gtgatttttc aaaggtcttc atcaaaaatc
     7141 agccagtcga cagctattta gagcatctgc tggaagagtt tcgttcttat gatattgaaa
     7201 agttgtcaac cctttatatc ggtggtggaa caccgacagc cctgtcggct ccgcaactgg
     7261 aggttttact gaatggcttg actaaaaact tggacttgtc tgtcttagaa gagttgacca
     7321 ttgaagccaa tccaggcgat ttgaatgcgg ataagatagc tgttttgaaa aattcggctg
     7381 tcaatcgtgt ttcgctaggt gtccagacct ttgatgataa gatgttgaaa aagattgggc
     7441 gcagtcattt ggagaaggat atttatgaaa atatcgatcg cctgaaactg gctggttttg
     7501 acaacatctc cattgatttg atttatgctc tgcctggtca gaccatggag caagtaaagg
     7561 aaaatgtggc taaagccatt ggactggata ttccccacat gagtttgtat agtttgattt
     7621 tagaaaacca tacggtcttt atgaaccgga tgcgacgtgg gaaattgcct ctgcctaagg
     7681 aggaactaga agcggagatg tttgagtaca tcattgcaga gctggagcga gcgggttttg
     7741 agcattatga gatttctaat ttctccaaac ccggctttga aagtcgtcat aatctcatgt
     7801 actgggacaa tgctgaatac tatggtattg gtgcaggggc atctggttat gtcaatggag
     7861 tacgttataa aaatcatggt cccattcgtc attatctcag tgcggttgag gaaggcaatg
     7921 cttgtattac agaagatcac ctgagtcaaa aggagcaaat ggaagaagaa atgttcttgg
     7981 gactccgcaa gaaatccggg gtttccatgg cgcgatttga ggaaaaattt ggacagtctt
     8041 ttgctggact ttatggagaa attgtcagag atttggttca acaaggcctc atgcagattg
     8101 agggtgacca cgttcgcatg acaaagagag gtctcttttt gggagatact gtagcagaac
     8161 gatttatttt ggagtaggat catgggctta acttatcaaa tgaaaatgaa aattcctttt
     8221 gatatggctg atatgaacgg tcatatcaaa cttccagatg tgattttgct gtcactgcaa
     8281 gtttcaggga tgcaatcgat tgaactggga gttagtgata aggccatttt ggaagactat
     8341 aatctggtct ggattatcgc agaatatgat attgaggtgg ttcgtttgcc tcgttttgcg
     8401 gaagaaatta ccatcgaaac ggaagccttg agctacaatc gacttttttg ctaccgtcgc
     8461 tttactattt ataatgaagc ggggcaggag ctcatccata tgatggcgac ctttgttctc
     8521 atggaccgcg acagtcgaaa agtccatgct gttgaacctg agattgtggc tccttaccag
     8581 tctgattttg ataaaaaact tatccgtgga ccgaagtatg aatccttgga agagccgatc
     8641 agcaaggatt accatgttcg tttttacgac ttggatatga atggtcatgt caataacagt
     8701 aaatacttgg actggatttt tgaggtcatg ggagcggatt ttttgaccca ctatattccc
     8761 aagaaaatca acctcaagta tgtcaaggaa gttcgaccag gtggggtgat tacatcggct
     8821 gttgaacgga ctggactgga aagcaagcat gaaattacaa gtgatggggt tatcaatgcc
     8881 caagcaatca ttacttggca agaaataaaa aaggtttagg gagaaataga tgaaatataa
     8941 aggctattta attgatttag acggaaccat ttataagggg aaagaccgaa tccctgctgg
     9001 agagactttt gttcatgaat tgcaaaagcg ggacattccc tatctctttg taaccaacaa
     9061 tacaacccgc actccagaga gtgttaagga gatgttggct cagaatttta atatcgatac
     9121 gcctctatcg actgtctaca cagcgacttt ggcaaccatc gactatatga atgatttggg
     9181 gcttgaaaag actgtctatg tcgtcggaga agcaggactc aaggaagcca tcaaggcggc
     9241 tggttatgtg gaatacaagg aaaaccctgc ctacgtggta gttggtctgg attggcaagt
     9301 cgactatgaa aaatttgcca cagcaactct tgctattcaa aagggtgccc attttatcgg
     9361 aaccaatcct gacctcaaca tcccgacgga acgtggtctt ttgccaggtg ctggctcact
     9421 gattacgctg cttgaagtag cgacacgagt gaagccggtt tatatcggaa aaccaaatgc
     9481 catcattatg gacaaggcgg ttgagcactt aggtttggaa cgtgaagagt taatcatggt
     9541 tggggacaat tatttgactg atatccgggc tgggattgac aatggcattc caacgctctt
     9601 ggtgacgaca ggttttacta aggcagaaga agtagctggc ctgccaatcg caccgacaca
     9661 tgtggtttct agccttgcgg agtgggattt tgatgaaaac taaattgacc ttttggggct
     9721 ctatgctctt tctcctctcc ctctcaatcc ttctgaccat ttatctggct tggattttct
     9781 atcctatgga gattcagtgg ctaaacttaa cgaatcgagt ctatctaaaa ccagaaacca
     9841 ttcaatacaa ttttcatatc ttgatgaatt atctgaccaa tccttttagt caggtcttac
     9901 agatgcctga ttttcgttcg tcagcagctg gtctgcacca tttcgcagtg gtcaagaatc
     9961 tctttcattt ggttcagcta gtagctctag tgacactgcc aagtttctat gtctttgtca
    10021 ataggattgt gaaaaaggac tttttgtctc tttatcgaaa aagtctcctg actctagtag
    10081 tcttacctgt gatgattgga cttgggggag ttttgattgg ttttgaccaa ttctttactc
    10141 ttttccatca aattctcttt gtgggagatg atacctggct ttttgatcca gccaaggatc
    10201 ctgttattat gattttgcca gagaccttct ttcttcatgc cttcctcctc ttttttgccc
    10261 tctatgaaag cttctttggg tatctgtgtc tgaaaagtcg taggaagtga aatgaaagat
    10321 gtttttaatt tgcatatata aaaatatata tcgtttaaaa ccatcgttaa gagtgaatta
    10381 accaaatcca attgtgtcaa tcgttcgcaa acagcctatt tttcttgaaa aaataggctt
    10441 tttttctaaa aatccctagt caagcgcttt atttttttgt ataatagaag tagcaaagta
    10501 tagataagaa gagaaaagca tgattacact atttctatca ccgagctgta catcatgtcg
    10561 taaggctaag gcctggttag aaaaacataa ggttcccttt gtggaacaca atattatgac
    10621 cagtccttta acaagaaaag aattgcaaca catcctttcc ttgaccgaaa atggtactga
    10681 tgacatcatt tcaactcgtt caaaaatttt tcaaaaattg aatattgatg tagagagtat
    10741 ttcggtatcg gaattgcttc atttgattga gcagtatcct agtcttttgc gtcgtccaat
    10801 tattattgat gccaagcgta tgcaaatcgg ttttaatgaa gatgagattc gtgcttttct
    10861 ccctcgtagt tatcgtaagc aagaactaaa agaagcaaga atgagagctg gtattagtta
    10921 atgaacaaac agtatagtta cccactagat ttgtcgtgga gcactgaaga acttgcttca
    10981 gtgctttctt tttttaatga tgttgaagct gcctatgaag gcaaagtaga ggctaaaaag
    11041 ttactggact cctataaggg attcaaagcg gtcgtgccaa gcaagagcga agagaaacgt
    11101 ttgggacgag aatttgaaac ggttagtggc tattcacttt accgagcagt tcaggctgcc
    11161 aaagaaaaag gggaaggaaa gatttctctt ggaaagtaaa tttgaatttg ctaaagagct
    11221 tgttaagaaa gcaggccagt acattcttga ccatatgcag gaagacttgc gtgttgaaac
    11281 caagtcctct ccaacagatt tggtgaccag actggacaaa gaagttcagg aactcttggt
    11341 tggtgagatt ttgtcccgtt atcctgagga taagatttgt gctgaagaag gttgtctgcg
    11401 agcctcggtt caagagggca aggtttgggt cattgatccc attgatggta ccaataattt
    11461 tgtagcccag caggaagatt ttgctgttat gatggcttat tttgaaaatg gtcagggaca
    11521 gtttggtctg atttatgatg tggtcaaagg ggattgttac cacggtggtg gggaatttcc
    11581 agtttgtcta aatgataggc ccctagctcc ttttaaaact aaaccacttg gagattttct
    11641 cattgcaggg aatagtggta tgctggaaac caatgaatgg gggctggctg atttgagccg
    11701 agcggttctt ggtgttcgtg tctatggaag tgcggccatt agttttgcca agattttgtc
    11761 agggcgtttg ttgacctatc tcacttatct gcaaccatgg gattatgccg cagctagtat
    11821 tttaggggaa agtctgggct atcgggttgt gacccttttt ggtgaagctc ctgattttca
    11881 aaccagacag cctgtcatga tggtgcctct tgagatgcag gaggaaattc agtcctatat
    11941 ttacgaaagg aaaagaactt aaatgcaatt tccagaagga tttgttgaaa aatataaaga
    12001 aatactagga gatgaggcaa gagattttct tgcctctttt gaggaggaag cggtttcggc
    12061 ctttcgggtc aatcccttaa aagaagagca actttccttt tctgatgcca ttactcaaac
    12121 cccttggggc cactatggga aggtttcagg gaaatcgcct gagcatgcta caggtttagt
    12181 ttattcgcaa gaacctgctg ctcaaatggt ggctcaagta gcccaaccca gtcctggtat
    12241 gaaggtcttg gacttggctg ctgcaccggg gggcaaatca actcaactgg cagcctatct
    12301 agcaggggag gggctacttg tttccaatga aatttcaagc aaacgggcta agattttggt
    12361 tgaaaacatg gagcgttttg gagcgacaaa tgtcgtggtg accaatgaat ctgccgaccg
    12421 cttggtcaag gtctttaaag gctattttga cttaatcgtt cttgatgccc cttgctctgg
    12481 tgaaggaatg tttcgtaagc aacctgatgc tatggactat tggagcttag attatccgag
    12541 tcaatgtgct agcttgcaaa gagaaattct ggaggatgca gtgaccatgt tagctgaagg
    12601 tggtcgtctg gtttattcga cctgtacctg ggcacccgag gaaaacgaag agattgtcaa
    12661 ttggttgctg gaagagtatg attttgactt gttgccagta gagcatatca atggaatggt
    12721 agctggtatt gacctgccag aaacggctcg gatgtaccct catcagttta agggagaggg
    12781 tcagtttgtt gcccatctac agtttaaggg taacaatcca gctcctaaat ttaaggcaag
    12841 taagagtaac ctcagccgtg aacaagttgc cttgtggcag gaatttgccc aaaaccattt
    12901 gaaggtcaat ctaccgggta tcttgcagat ttttggagac cagctttatc tcttgccaga
    12961 acttttgcca gatttaggga agctcaagat tgctcgcaat ggactgcatc tgggtacttt
    13021 taagaagaaa cgctttgagc ccagtttcgc tcttggttta gccttgaaac cgagtcaggt
    13081 cgaacagtcg gttgaaattg gccaagaagc gtttgtcaag tatgcggctg gagaaaccgt
    13141 tcagctggca gaaagtctgc caaatggttg gtaccaagtt ttggttaaag gcaatggctt
    13201 gggctttgca aaggttactg gaaatgtttt gaaaaattat tttccaaaag gcctcagatt
    13261 caaatgaaaa tgctagtcaa atatcttatt ctatgttata gtgaaagtat ggattttttt
    13321 agtaggatga ttcttgatat cttgattgcc atcacatgta gttttactac tcgatgaaaa
    13381 tcaaagagca aactaggaag ctagccatag atagctcaaa acactgcttt gaagagattt
    13441 tcaaagagta caagaagttt agttattagc gttcttaccg cttgtaaact agatttctca
    13501 taaaatagaa tcttttcctt ttagttgtaa actagtctgg gagagtagag aggtttgaga
    13561 tacctttcta gcttttggat tatcatctaa gaagagtaat ttcccttgca ttaaaaaggg
    13621 gaaaaagaga cacgaaatga ctataatggg tgacaatggg ggaagggata gacaagagat
    13681 tttatccaca tatgaaaaaa ggaggttagg aaagagtaat atagcctata ttatataaat
    13741 aatcaattgc gcagaaattt ggtaagaatt catgcgtcaa ctcataaaga actacttaaa
    13801 aaattcacag tattcataat tattttcgag gagaaaaaca gtgaaaaaaa gaaaaaagct
    13861 tgctctgtct cttatcgctt tttggctgac ggcttgttta gtaggctgtg ctagctggat
    13921 tgatcgtgga gaatccataa cggctgttgg ctcaactgcc ttgcaaccct tggttgaagt
    13981 agcggcagat gaatttggca cgatccatgt tggaaaaacg gtcaatgtcc aagggggagg
    14041 ttctggtaca ggcttgtccc aggttcagtc tggggcagtt gatataggaa actcagatgt
    14101 atttgctgag gaaaaagacg gaattgatgc ttctgctctt gttgaccaca aggtcgcggt
    14161 agctggcttg gctctgattg tcaataagga ggttgatgtt gataacctaa cgacagagca
    14221 acttcgtcaa atcttcatag gtgaggtaac caattggaaa gaggttggtg gtaaggactt
    14281 acccatctct gttatcaatc gggcagccgg ctctggctct cgtgctacct ttgatactgt
    14341 cattatggaa ggtcagtctg ccatgcaaag tcaggagcag gattcaaatg gagcggtaaa
    14401 atcaatcgta tcaaaaagtc caggagctat ctcttattta tctcttacct atatagatga
    14461 ttcggtcaaa agcatgaagt tgaatggcta tgacttaagt ccagaaaata taagtagcaa
    14521 taattggccc ttgtggtctt atgagcatat gtatacattg gggcagccca atgagttggc
    14581 tgcagaattt ctcaattttg ttctctcgga tgagacccaa gaagggattg tcaaaggatt
    14641 gaagtatatt ccgattaagg aaatgaaggt tgaaaaagat gctgccggaa ctgtgacagt
    14701 gttggaaggg agacaataat gaatcaagaa gaattagcta agaaaatgtt gcttccatca
    14761 aagaattctc gtctggagaa attaggaaaa ggtttgacct ttgcctgtct ttctttgata
    14821 gtcatccttg tggccatgat tttggttttc gtagcgcaaa aaggcttgtc gaccttcttt
    14881 gtcaatggtg tgaatatctt tgactttctt ttgggaggaa cttggaatcc ttctagtaaa
    14941 gaatttggtg cccttcctat gattttgggt tcctttatcg ttaccattct ctcagccctt
    15001 atcgcaacac cctttgctat tggtgcagca gtttttatga ccgaagtatc accaaaaggg
    15061 gcgaagattt tgcaaccagc tattgaactc ctggttggga ttccttcagt agtgtacgga
    15121 tttattggct tgcaagtcgt cgttcccttt gttcgcagtg tctttggtgg gactggtttt
    15181 gggattttgt cagggatttc cgtcctcttt gtcatgattt tgccgaccgt aacctttatg
    15241 acaacggata gcttgcgtgc ggttcctcgt tattatcgtg aggctagttt cgctatggga
    15301 gccactcgct ggcagactat ctggcgtgtg atcttgaagg cggcccgttc tggtattttc
    15361 actgcagtgg tctttgggat ggcgcgtgcc tttggtgagg ctctagctat ccagatggtt
    15421 gtcggaaact cagctgttat cccaacttcc ttgaccacac cagctgcaac tttaacttct
    15481 atattaacta tgggaattgg gaacactgtc atgggaactg taaataataa tgttctctgg
    15541 tcactggcct tggtactgct cttgatgagc ttagttttta acagtgtgat taaattgatt
    15601 acgaaagaaa gaggaaagaa aaattatgcg cgctaagaaa ttagataaac ttgcaacagc
    15661 tgtcctctat acgattgcta gcatcattgt gacaatcttg gcttccttga ttctctatat
    15721 cttggttcgg ggcttgcccc atatctcttg gtctttcttg actggaaggt cttctgcttt
    15781 tcaagcaggt ggtgggattg gcattcagct ttacaattcc tttttcctat tggtcattac
    15841 cttgattatt tctgtacctc tttctatggg agctgggatt tacttggctg aatatgctaa
    15901 aaaaggtcct gttaccaact ttgtgcgaac ttgtattgaa atcttgtcct ctttaccatc
    15961 agtggtggtg ggtctctttg gttacttgat ctttgtagtc cagtttgagt atggattttc
    16021 aatcatttca ggtgctttgg ccttgacagt ctttaacttg cctcagatga cgcgtaatgt
    16081 agaagatagt ttgaaacacg ttcaccatac ccaacgtgag gctggtctgg ctcttgggat
    16141 ttctcgctgg gagacagtgg ttcatgttgt tattccagaa gcgcttccag gtattgtaac
    16201 gggtgtcgtc ttggcatctg gtcgtatctt tggcgaagct gcagctctga tctatacagc
    16261 agggcaatcg gcgccagctc ttgactggtc taactggaat atcctcagtg tgactagccc
    16321 catctctatc ttccgtcaag cagaaacctt ggctgtccat atctggaaag tcaatagtga
    16381 aggcactatt ccagatggaa ccattgtatc agcaggttct gccgctgtgc tcctgatctt
    16441 tatcctgatt tttaactttg gagctcgtaa gttcggaagc tatctacaca agaaattaac
    16501 cgctgcctaa aggagaagcc atgtcaacat ataactggga tgagaagcat atccttacct
    16561 ttcctgaaga aaaagtagcc ctttctacta aggatgtcca tgtttattat ggtaaaaatg
    16621 aatccattaa ggggattgat atgcaatttg aaagaaataa aattacagct ttgattggtc
    16681 cgtcgggatc ggggaaatct acctacttac gcagtctcaa tcgcatgaat gataccattg
    16741 atattgctaa agtaactggg cagattctct atcgtggaat tgatgtcaac cgtccagaaa
    16801 tcaacgttta tgaaatgcgt aaacacattg gaatggtttt tcaacgcccc aatccatttg
    16861 ctaagtcaat ttaccgtaat attacctttg cgcatgaacg tgctggagtt aaggataagc
    16921 aagtcctaga tgaaatcgta gaaacctccc ttcgtcaggc tgccctctgg gatcaggtta
    16981 aagacgatct ccacaagtca gccttgacct tatcaggtgg tcagcaacaa cgtctctgta
    17041 tcgctcgtgc catctctgtt aagccagata tcctcttaat ggatgagcca gcctcagcct
    17101 tggatccgat tgcgaccatg caactagaag agaccatgtt tgagctcaag aaaaacttta
    17161 ccatcatcat tgtaacgcat aatatgcagc aggctgctcg tgcaagtgac tatacaggct
    17221 tcttttactt gggtgatttg attgagtatg acaagactgc aactattttc caaaatgcca
    17281 agctacagtc caccaatgac tatgtatctg gtcactttgg ttagaaagga aaccgtatga
    17341 cagatgcgat tttacaggta tcagacctgt ccgtttatta taataaaaag aaggctttga
    17401 atagtgtttc cctatctttc caacctaagg aaattacagc cttgattggt ccatctggat
    17461 cagggaagtc aaccctcctc aagtctctca accgcatggg agatctcaat ccagaggtga
    17521 ccacaactgg atccgtggtg tacaatggtc acaacatcta cagtccgcgt acagatacgg
    17581 ttgaattacg taaggaaatc ggaatggttt tccaacaacc taatcctttc cctatgacta
    17641 tctatgagaa tgttgtctac gggcttcgta tcaatggaat taaggataag caggttctgg
    17701 atgaagccgt agaaaaagcc ttgcaaggtg cctctatctg ggatgaggtc aaggatcgtc
    17761 tatatgattc agctattgga ttgtcaggtg gtcaacagca gcgtgtctgc gtggcccgtg
    17821 tcttggcaac tagtcctaaa atcatcctct tggatgagcc aacttcggct ttggatccga
    17881 tttcagctgg taagattgag gaaaccttgt atggtctaaa agacaagtac accatgcttc
    17941 tggtaacccg ttccatgcag caagcttcac gtatctctga taagacagga tttttcctag
    18001 atggagattt gattgaattt aatgatacca agcagatgtt ccttgatccc caacacaagg
    18061 aaacggaaga ctatattaca ggaaaatttg gataaggaga tgaaagatgt tacgatctca
    18121 atttgaagaa gatttagaga aattacataa ccagttctac gctatgggac aagaagtgct
    18181 ctcacaaatc aatcgtacgg tacgtgcttt tgtcacgcat gaccgtgacc tggcaaaaga
    18241 ggtcatagaa gatgatgcag aagtaaatga atacgaagtg aaactggaaa agaaatcatt
    18301 tgaaatgatc gcactccaac aaccagtctc tcaagatttg cgtacagtct tgactgtcct
    18361 taaggctgta tcagatgtgg agcgtatggg ggatcacgct gtagccattg cccaggcaac
    18421 catccgtatg aagggggaag agcgcatccc agctgtagag gaagaaatta aaaaaatggg
    18481 acgtgaagtt aaaagcgttg ttgaagcagc acttgatctt tatcttaatg gttctgttga
    18541 cgacgcatac cgggtggcct ccatggatga gcaaattaac cactattttg aaactatccg
    18601 tgaccttgcg actgaagaga ttaagaaaaa tccagaagcc attgttacgg gtcgtgatta
    18661 tttccaagtt atttcctact tggagcgtat cggtgactat gctaaaaata tctgtgaatg
    18721 ggttgtctac tttgaaacag gtaagattgt cgaactataa aatagtttaa ttctgtataa
    18781 aaaggagctt gaaatcaact gatggctcct ttttttgaac gaaaaaatat ttttgagata
    18841 aaaatttaaa aaacacttga caagtaactt ggatatcgtt ataattatac aaaattaaca
    18901 gagaggttgt ttatttatga aatcaaaaaa atggatattt gttttatgta attttcttgc
    18961 aagtttcttc ttagtagctt gccagtcagg ttctaatggt tctcagtcag ctgttgaggc
    19021 cattaagcaa aaggggaaat tagttgtggc aaccagtcct gactatgcac cctttgaatt
    19081 tcaatcattg gttgacggaa agaatcaggt agtcggtgca gacatcgaca tggctcaggc
    19141 tatcgctgat gaacttgggg ttaagttgga aatctcaagc atgagttttg acaatgtttt
    19201 gaccagtctt caaactggta aggctgacct agcagttgca ggaattagtg ctactgacga
    19261 gagaaaagaa gtctttgatt tttcaatccc atactatgaa aacaagatta gtttcttggt
    19321 tcgtaaggct gatgtggaaa aatacaagga tttaactagc ctagaaagtg ctaatattgc
    19381 agcccaaaaa gggactgttc cagaatcaat ggtcaaggaa caattgccaa aagctcaatt
    19441 aacttcccta actaatatgg gtgaagcagt caatgaattg caggctggaa aagtagatgc
    19501 tgttcatatg gatgagcctg ttgcacttag ttatgctgct aaaaacgctg gcttagctgt
    19561 cgcaactgtc agcttgaaga tgaaggacgg cgacgccaat gccgttgctc ttagaaaaaa
    19621 tagtgatgat ttgaaagaag tggtagacaa ggtcatccaa aaacttaagg atgaaggaac
    19681 ttaccaaagc tatcttgaaa aagcagcaag tctaactgaa gttgaagaat aagaaaaagc
    19741 agagttggat gtcattccaa ttctgctttt aaatagttta aaacattttc cagattgtct
    19801 agggacacct tggcaaattg ataaggacag gtgcttaaat aggcctcttc aaagaagtcc
    19861 aagcccagtt gactgtgttt gagactggcg attttaggat actgtctcag gtctagcaat
    19921 aaaccatcgt gtaggggata atgaggaagg ggacaaggtg ttttagttat cctttcctcg
    19981 atttgttttt ggtaagattc atgattggtc aagcgagcca aacgattttt ttcaaacaat
    20041 tgactgtcaa tatagagtga cagggccttt tgcataatga ggttgctgtc gtagtctagg
    20101 atatttttgt aggccacaaa tgcttctttg atagcatttg gaagaatgag tgctgtaata
    20161 cgaagggcag gaaaaaggct ggtcgagaag gacttgatat aaatgacacg ctcctctgta
    20221 tcaagatagt ggaaggtttg gcccttcttg gagtccaaat cacccagata atcgtcctct
    20281 acgatataga catcatactt ggcagctaag ttaagaatag atcgtttgtc ctgctcagaa
    20341 taggaatgtc ccagaggata gtgaaatcgg ggaatggtgt agaaaaattt aatttttcct
    20401 gttttgaagt ggccttccag ctcctccaag tcaatcccat caatgcctcg ttcaatcgtt
    20461 tgatagtcca gcccctgtgc aatcaagagg cgattcatcc gatggtaggt tggctgttcc
    20521 accaagattt ccttggcttg tctaggaaag gatatttgag agaggataaa caaggcttgt
    20581 tgggttccag aagtcagtac tagttggtta gccttgcagt agagagcttg ctcaaagagg
    20641 agtttgtgaa tggactgtct taggtcttct aatccttctt gattgtcata gtagttgaag
    20701 aggtagtttt ctcggccaat caaggtttca ttgacacaga gtcggaaatc gtcataggca
    20761 ctggcatgtt cgtcggtaac ctcgatttct aggtcttgat gttgcccttg ttctaataca
    20821 tagtagccac tctgaggctt ggcatagagg tattgttcgt gccgtaattc cagcagggct
    20881 cgttgaatgg tgtccttgct gcagtgaaag tcaaggctca gttgacggat agaaggcagg
    20941 cgactacccg tcggaaatcg ttcagactcg ataccatttt tcagatagga aacgacctct
    21001 ttgtacttgc tttgtttctt cattccagac ctcccttgat tttgttacat tgtacccttt
    21061 tttttccttc ttggcaatgt ctagagcgtt tctctcgttc acatctaggg gcaaatgtgg
    21121 tatacttagg agtaagattt atagaataac agacaagaaa gtgaatggat aagaacgtgc
    21181 aggaaccagt gaaattattt caatacaata ctcttggagc cttgatggct ggcctttatg
    21241 gtggtactat gacagtagga gaattgctag aacatggtga ccttggtttg ggaaccttgg
    21301 attccattga tggggaattg attgtcttgg atggcaaggc ttatcaggcc aaagggtcag
    21361 gagaccagcc agaaattgtg gaagtgtcac cagatgccct tattccttac gctgcagtgg
    21421 taccgcatca ggcagaggtc attttccgcc agcgctttga gatgacagac aaggaattga
    21481 aagaacgaat tgagtcttat tatgatgggg aaaatctttt ccgttctatc aagattcggg
    21541 gggaattttc acatatgcat gtgcgtatga ttcctaagtc aacacccgat accaagtttg
    21601 ctgatgtcgc aacccatcaa ccggaatata gtcgtgacaa tgttgcgggg actattgttg
    21661 gtttctggac gcctgagatt ttccatgggg tcagtgtggc aggctaccat ctgcacttca
    21721 tatcagatga tttgaccttc ggtggacatg tcatggattt tgtcatcaag gaaggcatta
    21781 tcgaggtggg agcagttgac cagttggacc aacgtttccc agtccaagac cgtcaatact
    21841 tgtttgctaa gttcaatgtt gacgagatga aaaaagatat tgaaaaggca gaataggaga
    21901 agaaaatgac cattcatatc attattacca tgttgctgtt gctagctttt ctgataggaa
    21961 gcatttggtt tgccaaaaag aaataccaga ttaatctagc tgtcttgggc ttgggtgcag
    22021 tcgctttctt tgtctcttcg cagattttgg aaaaactggt gcatatcttg attttgcatc
    22081 ctcaaaaaag acggtagtat tgccctcttg caagatcacc cgcttgtcta tattatctat
    22141 ggcctagcta tggcagcatt ttttgaggaa acggctcgtc ttgttttctt caaatggttg
    22201 gagaaaaaga gaagtttgga aaaggcagac gccttggcct atggactggg gcatggtggc
    22261 ttggagttga tttttctagg ccttactagt ttactcaatc tttacattgt tctttcggca
    22321 gttcaaactc agaatccaca ggttatgcaa ttactgtctg aaaatatgtt aaaaaccatt
    22381 cagtcacttt cggtctggca gatttatttg cttggttttg agcgaatctt ggcgcttggt
    22441 ttccaattac ttttgacagt ttgggtttac caagctgttc gccagaagaa atggatttat
    22501 ctcctagcag cctatggctt gcatgccttc tttgatctgg caccatctct ttcccaagta
    22561 ggctggttga caaatccagt cttggttgaa gtgattctag cactggagct cgttctggtc
    22621 gcctatggaa ccaaggaaat cttttgtaaa aaatcataaa aagggggaaa cctctttttc
    22681 ttatgcaaaa tccaaacaag gtatttttat ggtcgtcaaa tgtctctaaa aatggtataa
    22741 tggaatgaat tttgtaaaag gaagagtgac atgtctgtaa gagaaaaaat gcttgaaatc
    22801 ttagaaggaa ttgatatccg ttttcaggaa cccttgcata gctatagtta tacaaaagta
    22861 ggtggagagg ctgattattt ggtctttcca cgaaatcgtt ttgagttggc tcgcgttgtg
    22921 aaatttgcca accaagaaaa tatcccttgg atggttcttg gcaatgcaag caatatcatc
    22981 gttcgtgatg gtgggattcg tggatttgtc atcttgtgtg acaagctcaa taacgtttct
    23041 gttgatggct ataccattga agcagaagct ggggctaact tgattgaaac aactcgcatt
    23101 gccctccgtc atagtttaac tggctttgag tttgcttgtg gtattccagg aagcgttggc
    23161 ggtgctgtct ttatgaatgc gggtgcctat ggtggcgaga ttgctcacat cttgcagtct
    23221 tgtaaggtct tgaccaagga tggagaaatc gaaaccctgt ctgctaaaga cttggctttt
    23281 ggttaccgcc attcagctat tcaggagtct ggtgcagttg tcttgtcagt taaatttgcc
    23341 ctagctccag gaacccatca ggttatcaag caggaaatgg accgcttgac gcacctacgt
    23401 gaactcaagc aacctttgga atacccatct tgtggctcgg tctttaagcg tccagtcggg
    23461 cattttgcag gtcagttaat ttcagaagct ggcttgaaag gctatcgtat cggtggcgta
    23521 gaagtgtcag aaaagcatgc aggatttatg atcaatgtcg cagatggaac ggccaaagac
    23581 tacgaggact tgatccaatc ggttatcgaa aaagtcaagg aacactcagg tattacgctt
    23641 gaaagagaag tccggatctt gggtgaaagc ctatcggtag cgaagatgta tgcaggtggt
    23701 tttactccct gcaagaggta gtggggacct gacagagccc cgatcggtta atctatgaaa
    23761 aagaaggaat ttatgccaat tgaaaaaacc aattatcgaa ttcaaaaacg tctctaaagt
    23821 ttttgaagac agcaacacca aggttctcaa agacatcaac tttgagttgg aagaagggaa
    23881 attctacacc cttctaggtg catctggttc ggggaaatca actatcctaa acattattgc
    23941 aggtttactg gatgcgacga caggagatat catgctagac ggtgttcgta tcaatgatat
    24001 tccaaccaac aagcgcgacg tacataccgt cttccaatcc tatgccttgt tcccacatat
    24061 gaatgtgttt gaaaatgttg cctttccact tcgcttgcgt aaaattgata agaaagaaat
    24121 cgagcagcgt gtagcggaag ttctcaagat ggttcagttg gaaggttatg aaaaacgttc
    24181 catccgcaaa ctttctggag gacaacgtca gcgtgtggcc atcgcccgtg ctatcatcaa
    24241 ccaaccccgt gtggtcttgt tggacgagcc tttatcagcg ctggacttga aattgagaac
    24301 agacatgcag tacgaattgc gtgaattaca acaacgattg ggcattacct ttgtctttgt
    24361 cactcacgat caggaagaag ctcttgccat gagtgactgg attttcgtta tgaatgatgg
    24421 cgagattgtc cagtctggaa cccctgtgga catctacgat gagccaatca accactttgt
    24481 tgccaccttt atcggggagt caaacatctt gccaggtacc atgattgagg actacttggt
    24541 cgaatttaac ggcaaacgct ttgaagcggt tgatggtggg atgaagccaa atgaacctgt
    24601 tgaggtcgtt attcgtccag aggacttgcg cattaccctt cctgaagaag gcaaactcca
    24661 agttaaggtc gacacccagc tcttccgtgg agttcattat gaaattatcg cctatgacga
    24721 acttggaaat gaatggatga tccactcaac ccgtaaggcc atcgtgggtg aggaaatcgg
    24781 tctggacttt gaatcagaag acatccacat catgcgtctc aatgaaaccg aagaagagtt
    24841 cgatgctcgt atcgaagaat acgtggaaat cgaagagcaa gaagcaggtt tgatcaatgc
    24901 aatcgaggag gaaagagatg aagaaaacaa gctctaaact ctttgtagtg ccctacatgc
    24961 tttggattgc cctctttgta ttggcaccct tggtcttgat tttcggacaa tcctttttca
    25021 acattgaagg ccagtttagt ttagaaaatt ataaatctta ctttgcgtca caaaacttga
    25081 cctacctcaa aatgagtttc aactcagtgc tttatgcagg gattgtgacc tttgtgacct
    25141 tgcttatcag ctatccaaca gccctctttt tgacccgtct caagcaccgt caactctggc
    25201 tcatgctgat tatccttcct acctggatca atttgctcct taaagcctat gcttttatcg
    25261 ggatttttgg tcaaaatggc tctattaacc aattcttgga atttatcgga attggttcac
    25321 aacagttgct ttttaccgat ttttccttta tctttgtcgc aagctacatc gagctcccct
    25381 ttatgatttt gccgattttc aatgtcttag acgatatgga taataatctc atcaatgcta
    25441 gttatgacct tggtgcaact aagtgggaga ccttccgtca tgtcatcttc cctctatcta
    25501 tgaacggtgt gcgaagtggg gttcagtcgg tctttatccc aagtttgagt ctcttcatgc
    25561 tgacccgttt gattggtggg aaccgcgtta tcaccttggg gacggctatt gagcagaatt
    25621 ttctaaccaa tgacaactat ggtatgggtt caaccatcgg tgtgattctc atcctgacca
    25681 tgttcatcac catgtgggtg actaaggaaa ggagagaacg atgaaaaaat ttgccaacct
    25741 ttatctggga ctggtctttc tggtcctcta cctgcctatc ttttacttga ttggctatgc
    25801 ctttaatgct ggtgatgata tgaatagctt tacaggtttt agctggactc actttgaaac
    25861 catgtttgga gatgggagac tcatgctgat tttggctcag acatttttct tggccttcct
    25921 atcagccttg atagcgacca ttatcgggac ttttggtgcc atttacatct accagtctcg
    25981 taagaaatac caagaagcct ttctatcact caataatatc ctcatggttg cgcctgacgt
    26041 tatgattggt gctagcttct tgattctctt tacccaactc aagttttcac ttggcttttt
    26101 gaccgttcta tctagtcacg tggccttctc cattcctatc gtggtcttga tggtcttgcc
    26161 tcgactcaag gaaatgaatg gcgacatgat tcatgcggcc tatgacttgg gagctagtca
    26221 atttcagatg ttcaaggaaa tcatgcttcc ttacctgact ccgtctatca ttactggtta
    26281 tttcatggcc ttcacctatt cgttagatga ctttgccgtg accttctttg taacaggaaa
    26341 tggcttttca accctatcag tcgagattta ctctcgtgct cgcaagggga tttccttaga
    26401 aatcaatgcc ctgtctgctc tagtctttct ctttagtatt atcctagttg taagttatta
    26461 ctttatctct cgtgagaagg aggagcaagc atgaaaaaaa tctattcatt tttagcagga
    26521 attgcagcga ttatccttgt cttgtgggga attgcgactc atttagatag taaaatcaat
    26581 agtcgagata gtcaaaaatt ggttatctat aactggggag actatatcga tcctgaactc
    26641 ttgactcagt ttacagaaga aacaggaatt caagttcagt acgagacttt tgactccaac
    26701 gaagccatgt acactaagat aaagcagggt ggaacgacct acgatattgc cattccaagt
    26761 gaatacatga ttaacaagat gaaggacgaa gacctcttgg ttccgcttga ttattcaaaa
    26821 attgaaggaa tcgaaaatat cggaccagag tttctcaacc agtcctttga cccaggtaat
    26881 aaattctcca tcccttactt ctggggaacc ttaggaattg tctacaacga aaccatggta
    26941 gatgaagcgc ctgagcattg ggatgacctt tggaagccgg agtataagaa ttctatcatg
    27001 ctctttgatg gggcgcgtga ggtgctggga ctaggactca attccctcgg ctacagcctc
    27061 aactccaagg atctgcagca gttggaagag acagtggata agctctacaa actgactcca
    27121 aatatcaagg ctatcgttgc ggacgagatg aagggctaca tgattcagaa taatgttgca
    27181 atcggcgtga ccttctctgg tgaagccagc caaatgttag aaaaaaatga aaatctacgt
    27241 tatgtggtac cgacagaggc cagcaatctt tggtttgaca atatggtcat tcccaaaaca
    27301 gttaaaaatc aagactcagc ctatgccttt atcaacttta tgttgaaacc tgaaaacgct
    27361 ctccaaaatg cggagtatgt cggctattca acaccaaacc taccagcgaa ggaattgctc
    27421 ccagaggaaa caaaggaaga taaggccttc tatcccgatg ttgaaaccat gaaacaccta
    27481 gaagtttatg agaaatttga ccataaatgg acagggaaat atagcgacct cttcctacag
    27541 tttaaaatgt atcggaagta ggagataaac gtaagaagac gaatcagtca agctggttcg
    27601 tttttaagga atagaagtca gtttttagag ccctatcttt ttctattcta gttgtttatt
    27661 tgcttgccta gtagtatact aagcctatac tcttcaaacc acgtcagcgt tgccttgccg
    27721 tactcaagta cagcttgagg ctagcttcct agtttgcttt ttgattttta ttgagtatta
    27781 accttacaga aagcggcaac aaataatgaa aatgtctact tttttcaaaa aaagtttctg
    27841 gccaaccttt atgattgtta accaaactgt tatactattc catttaaagg atggcttgga
    27901 tcgacaatac ctaacaactg agtccatata ttgggtgata ggcaccttta tatttggaaa
    27961 tattctagta gctgtgttta gtaatatgaa aatttgggat aaaaagaaaa acggcagtaa
    28021 gaaaaaatat atcctgaaaa agtaatcaga gatgtaggga attggtctaa ttcaacggag
    28081 atcatttcca gttgacgcaa gcttaaaaaa acgttataat aagaaagttg agaattgatt
    28141 ttcacttgtc ttagtccaga gaaatggcgg tgctgcgagc catctaagct aggaagtcat
    28201 gctactcaat catacaattg cataagaaca agagaatgac aagttcattg aatgaaggtg
    28261 gtaccgcggt ttttcgccct tcgtgatatg agcttgtctt ttgatttttg gaggtgttga
    28321 tgaaaacatt tcttgtcaaa caaaagtttc gtcttggagg cgaacgcttc gctatcaagg
    28381 atgacagggg agaaattgcc tatcaggtgg agggatcatt ttttaagatt cccaaaactt
    28441 ttaccatcta tgatgcggct ggtgaacaag tcagtcagat cagtaaagaa atcttgacct
    28501 tgcttcctcg ttttgagatt cagcttcggg atggctcgag ttttgtcatt cgtaagaagt
    28561 tgaccttttg gcgagataag tatgagtttg ataatctagg tcttcgtatc gagggcaata
    28621 tctgggattt gaatttcaaa ttgctggatg atcgcgatca gttgattgcg gaaattaaga
    28681 aggaactctt ccatctgacc tctacctata ccgtaacggt tcttgaagac gcttatgcag
    28741 acctagtcat ttccctctgt gtcgcgattg actatgtgga aatactggaa agccaatcac
    28801 attaaacaag tgaataagga gacaatatga aacaactatc tagtgcacaa gtacgccaaa
    28861 tgtggcttga tttctggtcg accaaaggtc actcagtaga accatcagta agtttggttc
    28921 ctgtaaatga cccaactctt ttgtggatca actctggggt agcaaccctt aagaaatact
    28981 ttgacgggac cattatccct gaaaatccac gtattaccaa tgcccaaaag gctatccgta
    29041 ccaacgacat cgaaaacgta gggaagactg cgcgtcacca taccatgttt gaaatgttgg
    29101 ggaacttctc tatcggggat tacttccgtg acgaagctat cacttgggct tatgagcttt
    29161 tgacaagccc tgaatggttt gatttccctg ctgaaaaact ttacatgacc tactatccag
    29221 acgataaaga ttcttacaac cgctggattg aagtgggagt ggatccaagt cacttgattc
    29281 caattgagga caacttctgg gaaatcggtg cgggaccttc tggaccagat acagaaatct
    29341 tctttgaccg tggggaagcc tttgacccag aaaatatcgg tcttcgcctg cttgcagaag
    29401 atattgaaaa cgaccgttat attgaaatct ggaacatcgt tttgtcacaa tttaacgcag
    29461 accctgctgt tcctcgtagc gaatacaagg aattgccaca taagaacatt gatacgggcg
    29521 ctggtttgga gcgtttggtg gctgttatcc aaggggctaa gaccaacttt gaaacggacc
    29581 tcttcatgcc gattatccgt gaagtcgaga aattgtctgg taaggtttat gaccaagatg
    29641 gcgacaacat gagcttcaag gttatcgcag accacattcg ttctctttca tttgctatcg
    29701 gtgatggtgc ccttccagga aatgaaggtc gtggttatgt tcttcgtcgt cttctccgtc
    29761 gtgcttctat gcatggtcaa aaattgggta tcaacgagcc tttcctttac aaattggttc
    29821 caactgttgg aaaaatcatg gaaagctact acccagaagt gcttgagaaa cgtgacttta
    29881 ttgagaaaat cgttaagagc gaagaagaat catttgcccg tacccttcac tcaggtcaac
    29941 actttgccca aggcattgta gcagacttga aagaaaaagg tcaatctgtt atcgctggtt
    30001 cagatgtctt caaactctat gatacttatg ggttcccagt tgaattgact gaagaaatcg
    30061 ctgaagaagc tggtatgact gtagaccgtg aaggttttga agcagccatg aaagaacagc
    30121 aagaacgcgc gcgtgcctca gctgtcaagg gtggctcaat gggtatgcaa aatgaaactc
    30181 ttcaaaacat cactgtagaa agtgtcttca actacaatgc tagccaattg tcttctaaat
    30241 tggtagctat cgtggcggac aatgcagaag tagaagctgt ttcagaagga actgcctctc
    30301 ttatctttgc ggaaacgtca ttttatgctg aaatgggtgg acaggtagct gactacggac
    30361 aaatcttgga tgagtcaggt aaggttgtgg ctactgtgac caatgttcag aaagccccaa
    30421 atggtcaagc ccttcataca gttgaagtcc ttgcaccgct tgccttgaac caagaatata
    30481 ccttggcaat tgatagcaat cgccgtcacc gtgtcatgaa aaaccacact gcgactcatt
    30541 tgcttcacgc tgcccttcac aatatccttg gaaaccacgc aacacaggca ggatctctta
    30601 acgaagttga attccttcgc tttgacttta cccacttcca agctgtaact gctgaagaat
    30661 tgcgtgcgat tgaacagcaa gtcaacgaaa aaatctggga agctcttgaa gttaagacag
    30721 ttgaaacgga tattgacact gctaaagaaa tgggagctat ggccctcttt ggtgagaaat
    30781 acggcaagga agttcgtgtc gtgactatcg gtgactactc tattgaactt tgtggtggta
    30841 ctcatgttgg caacacttct gagattggtc tcttcaaaat tgtcaaagaa gaaggaatcg
    30901 gttcaggaac tcgccgtatc ttggcagtga ctggtaagga agcctttgaa gcctatcgtg
    30961 aacaagagga tgctcttaaa gctgtcgcag caaccttgaa agcacctcaa gtcaaggaag
    31021 tacctcacaa ggtagaagga cttcaagaac aacttcgtca acttcaaaaa gaaaatgctg
    31081 agttgaaaga aaaagccgca gctgcagccg caggcgatat cttcaaagat gctaaggaag
    31141 tcaacggtca tcgttacatt gctagtcaag tgtctgtatc cgatgccggt gcccttcgta
    31201 cttttgcaga taactggaaa caaaaagact actctgatct tcttgtccta gttgccgcta
    31261 tcggtgacaa agtcaatgtc cttgtagcaa gcaagacaaa agaccttcat gcaggaaacc
    31321 ttgtcaaaga attagcacca atcatcgatg gacgtggtgg tggtaaacca gacatggcca
    31381 tggcaggagg aagcaaccaa gctaagatcc aagaattgtt ggatgcagta gcaggtaaat
    31441 tgtaatcaag taaagatcta tccatttggg taggtctttt tgtgaataca aaaaagccaa
    31501 atccgcttgg acctagcttg gttattatga gctattagat ggtattgact gcccagacac
    31561 ttacggatct agctgagaca gggaattgtc cataaccttc ctcatcaatt gtaacttgac
    31621 cttggtggtt accaagtaaa tctacaaagg tttgattagt ccattcttga ccgacaaaca
    31681 ttgacttgct gttttcttgg tcatttgaga taaggactgc gattggggat tgattttcag
    31741 cacctgaacg tacccaaccg atacagttag catggtcaaa gtagtcattt tgttctccat
    31801 aggccaaatc ttttcggatg gctaggaggc ggtcaaggat ttctttgaaa tcttgttgag
    31861 catactgccc tgaaatccca tagtagtctc cgtaaaagac acatggaagg ccgtcttggc
    31921 gtaacaaaat gagggcatag gctgctggct tgaaccattc ttcaacggta gactcaaggg
    31981 cttgtcctcg ttgggtatcg tggttgtcga caaaagtcac agccttgtca ggcttgagtt
    32041 caaccaggct atctgtgaaa atgccacgaa ggtcatagtt tgcgccagct tgactggctt
    32101 caaagagatt ctggtggaga cgaacatcga caaggtcaaa gtgttcttcc gttttttcga
    32161 gatagtccag attggcttcc ttgtctgggt tccaaaattc accaaaaaca tagaaatcgt
    32221 caccgtattt ttccttcata tcgcggatga agttgcgcat aaagaaagag tcaatatgct
    32281 taacggcatc caaacggaaa ccagctacac cagtcgtttc catgaaccaa tcagcccagt
    32341 catagatgtt ttggatgact tcaggatgtt taaagtctag gtcggcatac atgaggtagt
    32401 cgtagtttcc gttttcgtta tcgaccaatt cctcgttagc ccagcccttg ttgtcccctt
    32461 ggatcagata aatcccagat ttactgcgtt tggcatcgta gtctgtaccg gtgaagtggt
    32521 accaatgcca gtggaagcca ttataggtat cttggcgacc atcgaaggta aaactagtcc
    32581 agccattgat ggtgaagggt tctccaagtt caactgtacg gtctacagga tcaacttcga
    32641 tgacctgaaa ggcttccctg tgatcggcag cagccttgtg gttgagaact acatcggcca
    32701 taggttgaat tccctgtgct ttaagggctt gaatggcttg aagatagtct tctttgaaac
    32761 catacttggt gcggacagtc cctttttggt tgaactctcc taagtcaaat aagtcataga
    32821 ccccatagcc gacatctttt tcgttggttg ccttgaaggc tggtggcatc cagacgtgac
    32881 tgatccccag atgagctagg tgtggagcat tttcagccag acgcgtccag tgttgaccgt
    32941 cgtggggcag ataccattca aagtattgca tgagtgtttg attttgcatg atgtttcctc
    33001 ttacttgtca atcttgttct ttattctatc ataaagtatc tcttggcgca aacgtttgcg
    33061 taagatagaa ggaaactatt ttaactactt aaaataaagt attgattttt ttgtatcaaa
    33121 gtgctagtat agcgatgtat aatacagata aagataggag ttgtcccatg attgaatttc
    33181 aaaatgttag taagttgtat ggtgataaag aggccttgag taatctcaat ttgcagattg
    33241 aaaatggaga gattatgggc ttgattggtc ataatggggc tggaaaatcg accaccataa
    33301 aatccctagt cagtatcatt tcacccagca gtggtcgtat tttggtagac ggtcaggagt
    33361 tatcggaaaa tcgcttggct attaaacgaa agattggcta cgtagcagac tcgcctgact
    33421 tatttttacg cttaacggcc aatgaatttt gggaattgat cgcctcatcc tatgatctga
    33481 gtagatctga cttggaggct agtctagcta ggctattgaa cgtttttgat tttgctgaaa
    33541 atcgctatca ggttattgaa actctttctc acggaatgcg tcagaaagtc tttgtcatcg
    33601 gagcactctt gtctgatccc gatatttggg tcttggatga acccttgact ggtttggatc
    33661 cccaggctgc ctttgatttg aaacagatga tgaaggaaca tgcacaaaaa gggaagacag
    33721 tcttgttttc aactcatgtc ctagaggtgg cagagcaagt ctgtgatcgg attgccattt
    33781 tgaaaaaggg gcatttgatt tattgtggta aggtagagga cttgaggaaa gaccacccag
    33841 accagtcttt ggaaagtatc taccttagtc ttgctggtag aaaagaggag gttgcggatg
    33901 cgtctcaagg tcattaaaaa attagttgat atcaatatcc tctattcatc tcaagaagct
    33961 aatctggcta atctacgaaa gaagcaggct aagaatcctg ggaaaaaagt aaatgtttcc
    34021 gctagagtcc taagttctta cattttttcc agtctcttga tgctcatctg ttttagtaat
    34081 atagccattc attttccttt tgaggaaata cctatttatt ttagctcgat ggttgctatt
    34141 ttactagtga ttgccttttc aacttcttta acggcctttt acaatgtctt ttatgagagt
    34201 aaggatttgg tatcgtatag gccctatgcc tttaaagaat cagagattat aattgctaaa
    34261 ggactgtctg tccttttgcc agctctaact ggaattgtac caatcctagc ttattttcta
    34321 gtcctctaca ttaggctagc tccttctcta tggctgggtt tgcctttgat gctactgtcc
    34381 ttgaccttat tatttgtctc tgtggctcta gtgatggtag tggcagtgca tttcttggct
    34441 caaactacgg tcttcagaaa gtatcagtct attttttcga atgtgatgat tgggatagga
    34501 gttctcatac ctttaatatt tgtcttcttt ctacagtcga cttttggaag tattgttgac
    34561 aaagttagag acattccatt tctcctttat cctcttcata tcttttacaa aatagcagtg
    34621 gagccttttt caatagaagc catattgggt ctgctcgctt ggatagcttt aactgttttc
    34681 ttgctttacc tgaccaaaaa gaaggtcctt cctcgttttt atgacgtgat cctgcttaac
    34741 agtgaggaga aggtcaaaaa agaacgtcgc agcaaggaga ggatttcaac tactaaaaag
    34801 ggctttttcc gtatggtttt acgctaccac ctcaccctct tgggacaggg gactggcgtg
    34861 attacagtgc tttttacaag tgctttcctt ccttatctca tgatgatcag tctgatttcc
    34921 aaaatccgag attctcagat agttccagac attcatcctc catactggtt acccttgttt
    34981 tttgtaggag tgtttatagc agttgtcaat aacaatatca ccagcctgca ttcaattgcc
    35041 ttgtccttgg agagggaaaa tcttgatttt ctgaagagtt taccctttga ctttgctcgt
    35101 tatgtgaaag tgaaattttg gattatcttt gctgttcagt cctttttacc aattctgact
    35161 ttgctcggtc tttctctata tctaggcttg tccatccttt cgatgattta ccttcttgta
    35221 gtctggatca ttgccagtgt catcctttct tgccaccatt actttaagga cgttaaaaat
    35281 ctgtcaacca attggagtag cattacggac ctggtgaatc gttcaaatgg catagtcgcc
    35341 atagttttat tgtttattta tagtgcaatc ctgatggccc ttgtaattgg gagcatattc
    35401 ttggttcagt ctctctcccc tatccttgcc atcaacttgg gagtaggagc tcttatcgtc
    35461 ttgcttgctc ttgctatttt tggctatcat tattacctgt cacgcatatt ggcagaaata
    35521 gaaaaaagat gagatagttg gttgcttgct tgataaattc aattcgacaa acgcttttat
    35581 agtttgttag aatgtagttg taaatgatta agattggtaa tcaaaaatat agggaggaat
    35641 gttttgaata agaaatataa tatagttcta ttattgttgt ttatagttta tttattggga
    35701 tatttttcaa tttcaaaaac gttaattcct ataatgtgtg tgatccaagt atttttgata
    35761 gaacatatat ttagagttcg aaatagaatg atgcaaatag gtgaaatttt aattattgtt
    35821 gcttctataa tattatttat tgatagtata ttgagtttgt aacaaaaggc ttctctataa
    35881 aatcaaattt tccagatatc tactgaagct gatttatttc ttcatctttc ttctactacc
    35941 tttgtcacta aatttgacag acacatattg ctgatacaac ctctctacct ataatctcac
    36001 agttaacctg aggctagttt catagtttgc tatttgattt tcgttgataa taaaaaatgc
    36061 tcctccaaga cggaagagca ttttttattg tgattcttac acatttactt cctagttttg
    36121 caggaagtct agtataccat tttttaaaag aagagtaaaa aagcaagggt agtttctttt
    36181 ttgagaattg tctaaaagtt tgatataatg gtagttatga atagaataag agtcagcaaa
    36241 agggttgaaa agaagcttgc taaggggcta gttttactag aagccagtga tcttgagaat
    36301 gtcaatctta aggatcagga agtagaggtg cagggtcagg aaggaaactt tcttgggact
    36361 gcctaccttt ctcagcaaaa caagggcttg ggctggtttg tcagcaaaga caaggtggcc
    36421 ttcaatcaag ctttctttga aacgttgttt agaaaagcca aagaaaagag aagcgcctac
    36481 tatcaagatg atttaacaac tacctatcgt ctctttaatc aagagggaga tggctttggg
    36541 ggtctgacag tggaccttta tggcgactac gccgtctttt cttggtataa ctcttatgtt
    36601 tatcagattc gtcagactat atcagaagcc tttagacagg ttttccctga ggttttaggg
    36661 gcttatgaga aaattcgctt taagggtttg gactatgaat ctgcccatgt ttatggtcaa
    36721 gaagcacctg actttttcac tgttttagaa aatggtgtcc tgtatcaagt ctttatgaat
    36781 gatggcttga tgacaggaat tttcctagac cagcatgagg ttcgcggtag tttagttgac
    36841 ggcttggcta tgggtaaatc cttactcaat atgttttcct acacagcggc tttttcagta
    36901 gctgcggcca tgggaggagc tagccagaca acttctgttg atctagccaa acgttcacga
    36961 gaattgtctc aagcgcattt tcaggcaaat gggctcagca cagacgagca tcgttttata
    37021 gtcatggatg tctttgagta tttcaaatat gccaaacgca aagacttgac ctacgatgtg
    37081 attgtcctag atccgcctag ctttgctcgg aataaaaaac aaactttctc tgtggccaag
    37141 gattatcaca agttgatttc ccagagtctt gagattttaa atccgggagg gattatcatt
    37201 gccagtacca atgctgccaa tgtttcccgt cagaaattta cagaacaaat tgataaaggc
    37261 tttgcaggaa gaagttacca gattttaaac aaatatggtc ttccagcaga ttttgcctat
    37321 aataaaaaag atgaaagtag taattacctc aaggtgatta gtatgaaggt tagtaaatga
    37381 aattaatcgt ttcagtaatg ccaagaagtt tagaggaggc tcaggctctg gatgccacga
    37441 ggtacctgga tgccgacatc attgaatggc gtgccgacta tctgcctaaa gaagcgattt
    37501 tgcaggtagc tccagccatt tttgaaaaat tcgcaggccg tgagttggtt ttcacgctac
    37561 gaactcgctc cgaaggtgga gaaatcgacc tttctccaga agagtatatc catctaatca
    37621 aggaagttgc gcaactctat caaccagact atattgattt tgagtactat agctacaagg
    37681 atgtttttga ggaaatgctg aacttcccaa atcttgtttt gagttaccat aatttccaag
    37741 aaacacctga gaacatgatg gaaatcttgt cagagttgac gatcctaaat ccaaaacttg
    37801 ttaaggttgc ggtgatggct cacacggagc aggatgtctt agacttgatg aactatacac
    37861 gaggctttaa aaccctcaat cctgaacagg aatatgtgac catttctatg ggtaaggtgg
    37921 gcaaggtctc tcgtatcact gcggatgtga ctggttcgag ttggtctttt gccagtctgg
    37981 atgaggttag tgcccctggg cagatttctc tagctagcat gaaaaaaatc agggagattt
    38041 tggatgaagc ttgatggcta tacacgttta gctgcagttg ttgccaatcc tattaagcat
    38101 tctatttctc ccttcatcca caatagagcc tttgaggcga cagctaccaa cgctgcttac
    38161 gtggcttggg agattgaagc gagtgacttg gcagaaacag tggccaatat tcgtcgctac
    38221 cagatgtttg gcatcaatct gtccatgccc tataaggagc aggtgattcc ttatttggat
    38281 gagctgagcg atgaagcgcg cttgattggt gcggttaata cggttgtcaa tgagaatggc
    38341 aatttaattg gatataatac agatggcaag ggatttttta agtgcttgcc ttcttttaca
    38401 atttcaggta aaaagatgac cctgctgggt gcaggtggtg cggctaaatc aatcttggca
    38461 caggctattt tggatggcgt cagtcagatt tcggtctttg ttcgttccgt ttctatggaa
    38521 aaaacaagac cttacctaga caagttacag gatcagacag gttttaaagt ggatttgtgt
    38581 gctttagaat atgtttctga actgcaagca aggattgccg agtcggattt gctagttaat
    38641 gccaccagtg tgggcatgga tggccaatcc tctcctgttc ctgaaaacat agtcttacca
    38701 gaaactcttt tagttgcaga tatcatatac caaccctttg aaacaccgtt tttgaaatgg
    38761 gctagaagtc agggcaatcc agcagtcaat ggtctgggaa tgttgctcta tcaagctgca
    38821 gaagcttttc aactgtggac aggcaaggaa atgccgacag aagagatttg gcagtcttta
    38881 acagaaaaat accaataaag aaagggagac tctcctatga aaatcagaat cgatattcct
    38941 caccatcctt atgatattca gattgaaaaa ggttgtatgg cccaggctgg tcagtggttg
    39001 cgagaactct ggcaaccgca aaaggtagtc attgtgacag ataaccatgt agcctctctc
    39061 tatgcagaga aggtcaagct cagcctagaa gatgctggtt ttcaggtagc tgtttttgat
    39121 ttcttagaag gtgaagaaag aaagaattta actactgttc agaaagtcta tgaatttcta
    39181 gtcaagcaag gtctgactcg tagcgatgga atcgttgctc ttggtggtgg cgttgttggg
    39241 gacctggctg gatttgtagc ctctacctat atgcggggta ttcactttgt tcagattccg
    39301 actagtttga cagctcaggt tgattcttct atcggtggaa agacaggcgt taatacacca
    39361 tttgctaaaa atatggtggg gacctttgcc caaccagatg gggttctgat tgatccactt
    39421 gttcttgaaa ccctcggaaa aagagagttg attgaaggga tgggtgaagt tatcaagtat
    39481 ggcttgattg aggatccaga actgtgggct ctcttgacgg gactgaatgg ttctgttgag
    39541 agtattttgg aacatgcaga gaccttgatt gaacattctt gtcaggtgaa gcgcaagatg
    39601 gtggttgaag atgagttgga caatggtatt cgtctttacc tcaattttgg ccacactatt
    39661 ggccatgcca tcgaagcgac tgccggttat ggcaaggtca tgcatggaga ggctgttgcc
    39721 atgggaatgg tacagatttc caaggttgct gaggaaaaag gcctcatgcc agctggcatt
    39781 acccaatcta tcacagagat gtgtcagaaa ttcggtttgc ctgttgacta tgaaaattgg
    39841 gaagttgaca agctttatca ggctcttact catgacaaga aagcgcgtgg taacaccttg
    39901 aaattggtct tggtgccaga gcttggttca gcgaccattc acccagtttc tctggaagag
    39961 atgaaagact acttggtaaa ataaggagag tgtatgagat atttaactgc aggagaatca
    40021 cacggccccc gtctaacagc tattattgag ggaattccag ctggacttcc attgacagct
    40081 gaggatatca atgaggacct tagacgccgt cagggtggct acggtcgtgg tggtcgtatg
    40141 aagattgaga atgaccaggt tgtctttact tcgggcgttc gccacgggaa gacgacaggg
    40201 gcgcctatta ctatggatgt catcaataag gaccaccaga aatggctgga catcatgtct
    40261 gcggaggaca ttgaagaccg ccttaaaagc aagcggaaaa ttactcatcc tcgcccaggt
    40321 catgccgatt tggttggggg gattaagtac cgttttgatg atttgcgaaa ttctttggag
    40381 cgttcatcag ctcgtgaaac caccatgcgg gtggcagttg gtgcagtagc caaacgcctc
    40441 ttggctgagc tggatatgga gattgccaac catgtcgtgg tctttggtgg caaggaaatc
    40501 gatgttcctg aaaatctgac agtcgctgaa attaagcaaa gagctgccca gtctgaagtt
    40561 tctattgtca accaagaacg agaacaggaa atcaaggact atattgacca aatcaaacgt
    40621 gatggtgata ccatcggtgg ggttgtggag acagtcgtcg gaggcgttcc agttggtctt
    40681 ggttcctatg tccaatggga tagaaaattg gatgcaagat tggctcaagc tgttgtctct
    40741 atcaatgcct ttaaaggggt ggaatttggt cttggctttg aggctggtta tcgtaaaggc
    40801 agccaagtta tggatgaaat tctctggtct aaagaagacg gttatactcg ccgtaccaat
    40861 aatctaggtg gttttgaagg tggtatgact aatgggcaac ccatcgttgt tcgtggggtc
    40921 atgaaaccca ttcctactct ttataaacct cttatgagtg tggatatcga aacccacgaa
    40981 ccttacaagg caaccgtgga gagaagtgat ccgactgctc ttccagctgc aggaatggtc
    41041 atggaagcag ttgtagcaac ggttctggcg caagaaatcc tcgaaaaatt ctcatcagat
    41101 aatcttgagg aactaaaaga agcggtagcc aaacaccgag actatacaaa gaactattaa
    41161 ggagttccta tggcaaaaac aatctatatc gcaggtcttg ggttgattgg agcctctatg
    41221 gcacttggta tcaaacgcga tcatccagat tatgaaattt taggttataa tcgtagtcaa
    41281 gcttcgagag atatcgcctt gaaagaaggt atgattgacc gtgcaacgga tgattttgct
    41341 agttttgctc ctttggcaga tgtcattatc ctcagcttgc caatcaaaca aactattgct
    41401 ttcattaagg agttggccaa tttggatttg cgagaaggcg ttattatttc agatgctggt
    41461 tcgaccaagt caaccattgt ggatgcggcg gagcagtatt tggctggcaa gtctgttcgc
    41521 tttgtcgggg cccatcccat ggctggtagt cacaagacag gggctgcttc ggcagatgtc
    41581 aatctttttg aaaatgccta ttatatcttt acaccttcaa gcctgacaag tcaggacacg
    41641 cttaaggaaa tgaaggatct gctttcaggt cttcatgctc gttttatcga gattgatgcc
    41701 aaggagcatg atcgtgtcac ttctcagatt agccattttc ctcatatttt ggcttctagt
    41761 ctcatggagc agactgcggt ctatgctcaa gagcatgaga tggcaaggcg ctttgcggca
    41821 ggtggttttc gagatatgac ccgaattgcg gaaagcgagc caggaatgtg gacctccatt
    41881 ctcttgtcca atagcgagat cattctggat agaattgagg atttcaagga acgtttggaa
    41941 gcgattggtc aggccattag taagggagat gaagagcaaa tttggaactt ttttaaccaa
    42001 gcgcgtgaac aacgccagac catggaaatc cataagcgtg gtggtgtgga tagctcttac
    42061 gacctctatg ttgacgttcc tgatgaagaa gatgtcatcc tgcggatttt ggaactgcta
    42121 cgtggaactt ccttggttaa tatccacatc aacgaggaaa atcgtgagga tattcacgga
    42181 atcctacaaa tttcatttaa aaatgctcaa gacttggaaa gagctgagca tctcataaca
    42241 gaaaatactg actatacagt cgtcatcaaa taaggagaag aacatgtcaa atatttacga
    42301 tagtgcaaac gaactcagtc gcggtctacg cggattacca gaatacaagg ctgttaaagc
    42361 agctaaagat gcgattgcag cagatgctga ggcaagcaaa atctttacag attatcttgc
    42421 ctttcaagag gaaattcaaa aactagcaca gacaggtcaa atgccagatg cgtccttcca
    42481 agctaagatg gaaggctttg gtaaacagat tcaaggaaat agcctcttgt cagaattctt
    42541 taccaagcaa caacaattgg ccatttacct ttctgatatt gaaaaaattg tttttgaacc
    42601 agtttcagaa ttgctgaaat aagaaaagaa ctatcctaaa gtcaggaatt tttaaggaat
    42661 ttctggcttt ttatgataaa ataggtaaaa gtattgcaag tatgaggtcc agtatgaaac
    42721 taaaaacaaa cattcgccat ttacatggta gtatccgcgt cccaggtgac aagtctatca
    42781 gccaccgttc cattatcttt ggaagtttgg ctgagggtga gaccaaggtt tatgatattc
    42841 tgcgaggtga agacgttctt tcgaccatgc aggtttttcg tgaccttggt gttgaaattg
    42901 aggataaaga tggggttatt accattcaag gtgtaggcat ggctggctta aaagcgccac
    42961 aaaatgccct taatatggga aattctggca cctcgattcg cctgatttca ggtgtccttg
    43021 ctggtgcaga tttcgaagta gagatgtttg gagatgatag tctttccaaa cgtcctatgg
    43081 accgtgtgac ccttccactg aaaaaaatgg gcgtcagcat ttcagggcaa actgaacgag
    43141 acttgcctcc ccttcgctta aaagggacga aaaacctaag acctattcat tatgagttgc
    43201 caattgcctc tgcccaagtc aagtcagcct tgatgtttgc agccttacaa gctaaggggg
    43261 agtcagttat tatcgaaaaa gagtacaccc gtaatcatac tgaagatatg ttgcaacaat
    43321 ttggtggtca tttaagtgtg gatggtaaga aaatcacagt ccaggggcca caaaaattga
    43381 caggacagaa ggtggtcgta ccaggagata tttccagtgc agccttttgg ttagtcgcag
    43441 gtttgattgc tccaaattct cgtctagtgc tgcagaatgt ggggatcaac gaaactcgca
    43501 ccggtattat tgatgtcatt cgtgccatgg gtggaaaatt ggaaataact gaaatcgatc
    43561 cagtcgctaa atctgctacc ttgattgttg agtcttctga cttgaaagga acagagattg
    43621 gtggcgcttt gattccacga ttgattgatg aattgcccat tattgccctg cttgcgactc
    43681 aagcccaagg tgtaacagtt atcaaggatg ctgaggagct caaggtcaag gaaacagacc
    43741 gtattcaggt tgtggcagac gccttaaata gtatgggagc agatattact cctacggcag
    43801 atgggatgat tatcaaagga aaatcagctc ttcacggtgc tagagtcaat acgtttggtg
    43861 accaccgtat cggcatgatg acagctatcg cagccctctt ggttgcagat ggagaggtgg
    43921 agcttgaccg tgcagaagcc atcaatacca gctatcctag tttctttgat gatttggaga
    43981 gcttgattca tggctaaggt gttattaggg tttatggggg ctggaaaatc gactattgca
    44041 agaggcttgg accctaatta ccttgatatg gatgctctga ttgagaagcg cctaggtatg
    44101 tccattgcga attttttcgc tgaaaaggga gaatcagcct ttcgtcaggt agaatcagaa
    44161 gtcctagctg atttactaca aacagaccaa gtcgtgtcaa ctggaggagg agtggttatt
    44221 tctcagagaa atcgtgactt actcaagact aatacagata acatctacct gaaagcagat
    44281 tttgaaaccc tctaccaacg tatcgcagct gataaggaca atcagcgacc gctttttcta
    44341 aataatagca aggaagaact agtagctatt tttcaagaaa gacaggcttg gtatgaggaa
    44401 gtggctagtc gggttttgga tgtgaccaag ctaagcccag aggaaattat agaggaacta
    44461 agatgaaaat tgcttatcta ggtcccaagg gatcattttc acaccacgtt gtgcagacag
    44521 cttttcctca tgaggaattg caggcttttg ccaacattac agatgtcatc aaggcttatg
    44581 agcaaggatt agtggactat tctgtggtgc cagttgaaaa ctctattgag ggtagtgttc
    44641 atgaaacctt ggactatctt tttcatcagg ctcacatcca agcagtagca gaaatcgttc
    44701 agcctattca tcagcagttg atggtggttc caggccatac taagattgaa aagatttttt
    44761 cacatccaca ggccttggct caaggaaaga aattcatcga tgaacaatat ccagaggctc
    44821 aaatcgaggt aacagctagt acagcttatg cggcccgttt tatttccgaa catccagatc
    44881 agccctttgc agcagttgca cctagaagtt ctgctgaaga atatggattg gaactgattg
    44941 ccgaggatat tcaggaaatg gaagccaatt tcacccgttt ctgggttcta ggagctgaaa
    45001 agcctagtat tcccttgcaa gcacaaactg aaaagatgag tttggccttg acattacctg
    45061 acaaccttcc aggtgcactt tataaggccc tgtcgacctt tgcttggcga ggaattgact
    45121 tgacaaaaat tgaaagtcgt ccactcaaga cagcactggg tgaatacttt ttcattatcg
    45181 atgtggatta taccgataag gacttggtcc actttgccca aaaagaatta gaagcgattg
    45241 gaatccagta taaaattctg ggtacctatc ctatttatcc aatatcagac catggaaagg
    45301 agagaagatg agtaaagaaa atcccttaag tcatcatgag cagttgcgtt atgattattt
    45361 gctaaaaaat attcactatc tcaatgagag agaaaaaaat gagtttgcct atttgcaaga
    45421 aaagctaact cttgctaggg gaaatagtag ctctagcttg gaacaagaaa gagaagagca
    45481 ggttgactta ccaagctatg cgaaccggag tcgctcacaa tccaaatcac aagcactctc
    45541 tttccctcca aaaaagaaaa gacggaagct ccgtcttaaa cgaattttta tggtgatttt
    45601 ttcacttttg gtctgtgtgg ctttggccat ggtattcatg tttttgcgtg gttaccaaga
    45661 tgctagcgca aagaaaactg ctgatgcccg ggcagctcaa gtagaagtct ttaatggtca
    45721 ggacactaga gatggagtta atattttaat catgggtact gatggtcgaa tcggccagaa
    45781 cagtgttgag acacgaactg actctattat ggtattaaat gtcgggggct cagataagaa
    45841 aatgaagcta gtcagtttca tgcgtgataa tttggtctat atagatggtt atagtcaagt
    45901 gattaatggt agaaaacaga cagataacaa gttaaacgta gcctacgagt taggagaaca
    45961 agaggggcaa aaaggggcag aaatggttcg ccaagtcttg aaagataatt ttgacttgga
    46021 cattaagtac tacgccttgg ttgatttcca ggcctttgcc acagcgattg acacgctttt
    46081 ccctgatggg gtgacgattg atgctcaatt ttcaacattg aatgggcgtc ccctaacaga
    46141 agctacagtc ggagatgatt tatatgctac cgagactgag tctccaaccc aaaccattaa
    46201 agtcggaaaa cagcagatga atggctcgac cctgctcaat tatgctcgtt tccgtgatga
    46261 tgatgaggcg gattacggcc gtacaaaaag acagcaacaa gttttaacag caattttaga
    46321 gcaaattaaa gatcccacta aacttttcac tggttctgaa gctcttggaa aggtttttgc
    46381 tatgacctca accaacgtac cctatacttt cctcctaaca aacggtttat ctgttttgga
    46441 tggagcaaaa aatggtattg aaaaattgac gattccagaa ctgggtgact gggtagatgc
    46501 ctatgatgtt tatggaggct tgggcttgct ggttgatcaa aacaaatatc aaaccaagct
    46561 cgctcaaatg ggcttgagat aagataatac tcaatgaaaa ttaaagtgca aactaggaag
    46621 ctagccgcag gctgctaaaa acacagtttt gaggttgtag ataagactga cgaagtcagt
    46681 tacctatacc tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa
    46741 gacagaaaaa tcaaagtttg atagctattt ggatagcagt caggctttga ttttttacag
    46801 tctgcaatag attttcactc cttgtttgtg gtataatgaa acgatacgat agaaagaata
    46861 atgaacaata tgactgattt aaaagcaatt caggctcgta gtctggagat ggctgaatat
    46921 tttgtggcct tttgtaaaga acatgatttg ctctgttatc tctgtggcgg aggcgctatt
    46981 ggtgcccttc gaaacaaggg atttattcct tgggacgacg acctagactt ttttatgcct
    47041 cgtaaagatt atgagaaatt agcagaatta tggcctcgtt atgcagatga acgttatttc
    47101 ttgtcaaaga gtcacaagaa ttttgttgat cgtaatcttt ttattaccat tcgtgacaag
    47161 aaaaccacct gtatcaagcc ttatcagcag gatttggatt tgccacatgg tctggccttg
    47221 gatgttttgc ctttggatta ttatccgaaa aatccagctg agcggaaaaa acaggttcgt
    47281 tgggccttga tttattcact cttttgtgcg caaactattc cagaaaagca tggtgctctc
    47341 atgaaatggg gaagtcgcat tttactgggt ttgactccaa aatctctccg ttatcgcatc
    47401 tggaaaaaag ctgagaaaga aatgactaag tatgatttgg ctgattgtga tggcattaca
    47461 gaattatgct caggtcctgg ctacatgaga aacaagtacc caatcacatc ttttgaatac
    47521 aatcttttct tgccatttga aggaacagag atgcctattc caatcggcta tgatgtctat
    47581 ctcagaactg cttttgggga ttatatgacg cctccaccag cagacaagca ggtaccgcat
    47641 catgatgctg tcatcgctga tatggataag tcttatacag aatacaaggg agaatatggt
    47701 ggctaagaaa aaaatcttat tttttatgtg gtctttttct cttggaggtg gtgcagagaa
    47761 gattctatca accattgttt caaatctgga tccagaaaag tatgatattg atattcttga
    47821 aatggagcac tttgacaagg gatatgaatc tgttccaaag catgtacgca ttttaaaatc
    47881 ccttcaagat tatcgccaaa ccagatggtt acgagctttt ttgtggagaa tgagaattta
    47941 ttttccaaga ctggctcgtc gtttgcttgt aaaagatgat tatgatgttg aagtttcttt
    48001 taccattatg aatccaccac tgttgttctc taaaagaaga gaagtcaaga agatatcttg
    48061 gattcatgga agtattgaag aatttcttaa ggatagctct aaaagagaat cacatagaag
    48121 ccagttggat gctgcgaata caattgtagg gatttcaaaa aagaccagca attctatcaa
    48181 ggaagtttat ccagattatg cttctaaatt acagacaatc tacaatggat atgattttca
    48241 gactattcta gaaaaatctc aagagaagat cgatatcgag attgctcctc aaagtatctg
    48301 tactatcgga cggattgagg aaaataaggg ttctgaccgt gtagtggaag tgatacgatt
    48361 attacaccaa gagggaaaaa actatcatct ctattttatc ggggctggtg atatggaaga
    48421 ggaactgaaa aaacgagtca aagagtatgg gattgaggac tatgtacatt tccttggtta
    48481 tcaaaaaaat ccttatcagt atctatctca gacgaaagtt ctcttgtcta tgtctaaaca
    48541 agaaggtttt cctggagtgt atgtggaggc cttgagtctg ggactccctt ttatctctac
    48601 ggacgttgga ggggctgagg aattatccca agaaggacga tttggacaaa tcattgagag
    48661 caatcaagag gcagctcagg cgattactaa ttacatgact tctgcctcaa actttgatgt
    48721 cgatgaggct agccaattca ttcaacaatt tacaattaca aaacaaatcg aacaagtaga
    48781 aaaactatta gaggagtagc atggaaactg cattaattag tgtgattgtg ccagtctata
    48841 atgtggcgca gtacctagaa aaatcgatag attccattca gaagcagacc tatcaaaatc
    48901 tggaaattat tcttgttgtt gatggtgcaa cagatgaaag tggtcgcttg tgtgattcaa
    48961 tcgctgaaca agatgacagg gtgtcagtgc ttcataaaaa gaacgaagga ttgtcgcaag
    49021 cacgaaatga tgggatgaag caggctcacg gggattatct gatttttatt gactcagatg
    49081 attatatcca tccagaaatg attcagagct tatatgagca attagttcaa gaagatgcgg
    49141 atgtttcaag ctgtggtgtc atgaatgtct atgctaatga tgaaagccca cagtcagccg
    49201 atcaggatga ctattttgtc tgtgattctc aaacatttct aaaggaatac ctcataggtg
    49261 aaaaaatacc tgggacgatt tgcaataagc taatcaagag acagattgca actgccctat
    49321 cctttcctaa ggggttgatt tacgaagatg cctattacca ttttgattta atcaagttgg
    49381 ccaagaagta tgtggttaat actaaaccct attattacta tttccataga ggggatagta
    49441 ttacgaccaa accctatgca gagaaggatt tagcctatat tgatatctac caaaagtttt
    49501 ataatgaagt tgtgaaaaac tatcctgact tgaaagaggt cgcttttttc agattggcct
    49561 atgcccactt ctttattctg gataagatgt tgctagatga tcagtataaa cagtttgaag
    49621 cctattctca gattcatcgt tttttaaaag gccatgcctt tgctatttct aggaatccaa
    49681 ttttccgtaa ggggagaaga attagtgctt tggccctatt cataaatatt tccttatatc
    49741 gattcttatt actgaaaaat attgaaaaat ctaaaaaatt acattagaac gggggtgacc
    49801 aagtgattga tgggaaacga ttattattta gtttgaccat agtcagttat gccttgacgc
    49861 tagtaagtgg aattgtgtat ctgtttaata ataataatgt tagcttactt tctactttat
    49921 tgttcttgtt ggttagtagc ttaattgctt gttggaatga tatcaagtat tacttaatcc
    49981 attttatttt ctatttaacc atttttgtat ttctggtatc aagaccgacc attgattatt
    50041 ttagggatgg tgctttggat acctatcatc caatagccta tcgttttgcc tttatagttg
    50101 tcatggtttc gattctgggc ttgaccacag gaggcattct ggctcgttac ttcatagcta
    50161 ggaagaaaat aaaagtagca aatataggaa attctctaaa agaggtttat atcaagcggt
    50221 tacgctttgt atcactagga gtttttcttc taacttatcc tttctatttc attcggttat
    50281 ttgaacggct cttgtatcgt ttgcagactt cctactatgc ctactatgca aattttgaaa
    50341 gtaaactgcc ttattttacc tacattttgt ctacctttac ggtctatgca atgtgtatgt
    50401 atctggcaac caagccaaag aaattgcagg ccacagcagt gcttgtctcc tttattgcag
    50461 ctaacactat tcatttggca attgggacac gaaatccctt tattttaagt attttatttg
    50521 cttttgttta ttactttatg cgggagcaag ctgaaaaagg aaaatggatt gggtttaaag
    50581 aaaagttagc gatttttgta ggttctccta ttctcatgtt agcgatggga gtactcaatt
    50641 atgtacggga taatgtccaa gtttcccata caggtttctg ggatatctta cttgacttta
    50701 tctataaaca agggactagt tttggtgttc tggctcgagg ttttctattt aacagtagcc
    50761 tcccttaccg agatttccgt aattttactt ttggtcctgt tcttgattat tttgcaaggg
    50821 ggagtttggg agccattttc ggaggaaaag cctttgaaca tacaaccaat agtgtggaac
    50881 tagctattga tagtaatagt tatgcccaca atctatccta tcttgtcttg aacaaggaat
    50941 acttgaaagg gcatggtatc ggaagtagtt atatcatgga gttgtatacc gactatggta
    51001 tgattggagt ctttctgctt agtttcttac tcggcgtatt atttatagcc atgctgcaag
    51061 tagcctatcg ctcaaggaca atcctatttg ctttatccct actcatcttg aataatctat
    51121 tctttatgcc aagaagcagc ttttcagaaa gtttcttcaa tttatttaca atgcaattct
    51181 ggggaattgt tcttgtgatt atatttgtag caaaaatgct tacaaaggaa aactagtatc
    51241 tactaaacaa aggagaaaaa aatcatgttt gaacattatt cagtagctga tttgtttgca
    51301 aatctttata aaaagcgaaa agcaaatatt ttagctctca tcgctttatt tgctctcatt
    51361 gctgtaccat ttacaattaa agcagttagg aataaaaaca ctgtcaaaga tacaacaagt
    51421 tattcaactt atcttatcta taaaatcact cctccaaaag agtcggccaa aacgattttg
    51481 aatcatcaaa ttggtggtta tagtgatttt tatgggaaat tgattgatgg taatttgaat
    51541 ggagcttatc ttttcaatga tgtagaaccc agtgagttga aaaaaattgc cagtgaatta
    51601 gacacgacag aaacaacctt gaaaaattca acgaatgact attggtggaa aaaattgacc
    51661 gtctactata tgattgacga tgcaggggtt ggtgtgaaaa ttttgacatc aagtaaagat
    51721 gccaatgact tgttagagaa aaaaattgat gggttgattg agaaatttaa acatgcctat
    51781 gcaaatgtga aaattgaaaa actggaaacc atcaactcta aagaattgaa cgcaaatggt
    51841 gaaacagcgc ttggcttaaa tgtgaaaaat ctgattcttc gtttagttgt tattggagtg
    51901 gtttgtgtga ttttggttgt gatgggaaat gtgttagttt atctctttaa tccaacaatc
    51961 aatagagtag gtgatttttc tcagtatcaa attgattttg taacagagat tacaacaatt
    52021 gctaacctag cagatgtttt gtcatacaaa aatactggac aggaattgac catcgttagc
    52081 tcaaataaag ctatcctaga taaattgaaa cagagtcaag aagctttaaa aggaatgcat
    52141 tttgtagatt tacaggatgt atcatctctt ttggaaagag atacagtcct tcttgttgaa
    52201 gagtacggag tgactcgtta taagaaattt gagcaaagtc ttcaaattct cagaaactta
    52261 aatcgttcta tccttggtgt agcaaccttt aaattataag tattctgatg tataaggtct
    52321 tcaaaatcgg ctaagagctg attttgaagg ctttttctat ctgtctgcag aaattttctt
    52381 ttggagtctc ctatagaaag accctaggga aaatctatcc gtatagagga gccttctttt
    52441 gataaaatcg taaaaatcta gtataataga tagaactgaa agtatgaggt tactagcaat
    52501 gaaaatgaaa caaattagtg atacaacttt aaaaatcacg atgtctttag aggatttgat
    52561 ggatcgtgga atggagattg ctgactttct cgttcctcaa gaaaaaacag aagagttctt
    52621 ttatgctatc ttggatgagc tagagatgcc tgatagcttt ctggatacag gcatgttgag
    52681 cttccgtgtg actccaaaac ctgataaggt agatgtcttt gtgaccaagt caaagattga
    52741 ccaaaatcta gattttgaag acttatcgga tttgccagat atggaagaat tggctcaaat
    52801 gtctccagat gaatttatca aaaccctgga aaaaagcatc gcagacaaaa ccaaggatga
    52861 tatcgaagcc attcaatctc ttgagcaagt tgaagccaag gaagaagaac aagagcaggc
    52921 tgaacaagaa gctgagagta agaaagaacc ttacatctac tacatccttt cttttgctaa
    52981 gttggctgac ttggtagctt ttgccaagac agtgactttt gaaatggaaa cttctgaact
    53041 ctacaaaatg aacgagcgct attatttgac cattttagtg gatattgaaa atcatccaag
    53101 cccatatcca gcttggctgt tggcccgtat gcgcgagttt gcagacgata gtgatatcag
    53161 tcgctcagtc ttacaagagt atggtcaagt cttgatgagt cacgatgcag tgctcaatct
    53221 gcaaaaaatc ggctaatctt ttctggaaag ctattttcag attttaagaa gagcgaatcg
    53281 tctgattcgt tttttctttt tatactgaaa tagtgattta ctataatagg aattttcaca
    53341 aaattctgtt ataatggcta tattagaaaa tttcgaggag ataaagatga cagttaaaat
    53401 tgctttacta ggatttggta ccgttgcaag tggtgtgcct ttcctcctaa aggaaaatgg
    53461 aggaaaaatc aatcaatcag cacattcaga tatcaaagtt gctaaggtat tggtcaagga
    53521 tgaagatgaa aaaaatcgct tgcttgcagc agggaatgac tttaactttg taaccaatgt
    53581 ggatgatatt ttatcagacc aggatattac tatcgtagtg gaattgatgg ggcgtattga
    53641 gcctgctaaa acctttatca ctcgtgcctt ggaagctgga aaacacgttg ttactgctaa
    53701 caaggacctt ttagctgtcc atggcgcaga attgctagaa atcgctcaag ctaacaaggt
    53761 agcactttac tacgaagcag cagttgctgg tgggattcca attcttcgta ctttagcaaa
    53821 ttccttggct tctgataaaa ttacgcgcgt gcttggagta gtcaacggaa cttccaactt
    53881 catggtgacc aagatggtgg aagaaggctg gtcttacgat gatgctcttg cggaagcaca
    53941 acgtctagga tttgcagaaa gcgatccgac gaatgacgta gatgggattg atgcagccta
    54001 caagatggtt attttgagcc aatttgcctt tggcatgaag attgcctttg atgatgtagc
    54061 ccacaaggga atccgcaata tcacaccaga agacgtagct gtagctcaag agcttggtta
    54121 cgtagtgaaa ttggttggtt ctattgagga aacttcttca ggtattgctg cagaagtgac
    54181 tccaaccttc ctacctaaag cgcacccact tgctagtgtg aatggcgtaa tgaacgctgt
    54241 ctttgtagaa tctatcggta ttggtgagtc tatgtactac ggaccaggtg cgggtcaaaa
    54301 accaactgca acaagtgttg tagctgatat tgtccgtatc gttcgtcgtt tgaatgatgg
    54361 tactattggc aaagacttca atgaatatag ccgtgacttg gtcttggcaa atcctgaaga
    54421 tgtcaaagca aactactatt tctcaatctt ggctctagac tcaaaaggtc aggtcttgaa
    54481 gttggctgaa atcttcaatg ctcaagatat ttcctttaag caaatccttc aagatggcaa
    54541 agagggtgac aaggcgcgtg tcgttatcat cacacacaag attaataaag cccagcttga
    54601 aaatgtctca gctgaattga agaaggtttc agaattcgac ctcttgaata ccttcaaggt
    54661 gctaggagaa taagatgaag attattgtac ctgcaaccag tgccaatatc gggccaggtt
    54721 ttgactcggt cggtgtagct gtaaccaagt atcttcaaat tgaggtctgc gaagaacgag
    54781 atgagtggct gattgaacac cagattggca aatggattcc acatgacgag cgtaatctct
    54841 tgcttaaaat cgctttgcaa attgtaccag acttgcaacc aagacgcttg aaaatgacca
    54901 gtgatgtccc tttggcgcgc ggtttgggtt cttccagctc ggttatcgtt gctgggattg
    54961 aactagccaa ccaactgggt caactcaact tatcagacca tgaaaaattg cagttagcga
    55021 ccaagattga agggcatcct gacaatgtgg ctccagccat ttatggtaat ctcgttattg
    55081 caagttctgt tgaagggcaa gtctctgcta tcgtagcaga ctttccagag tgtgattttc
    55141 tagcttacat tccaaactat gaattacgta ctcgcgacag ccgtagtgtc ttgcctaaaa
    55201 aattgtctta taaggaagct gttgctgcaa gttctatcgc caatgtagcg gttgctgcct
    55261 tgttggcagg agacatggtg accgctgggc aagcaatcga gggagacctc ttccatgagc
    55321 gctatcgtca ggacttggta agagaatttg cgatgattaa gcaagtgacc aaagaaaatg
    55381 gggcctatgc aacctacctt tctggtgctg ggccgacagt tatggttctg gcttctcatg
    55441 acaagatgcc aacaattaag gcagaattgg aaaagcaacc tttcaaagga aaactgcatg
    55501 acttgagagt tgatacccaa ggtgtccgtg tagaagcaaa ataaagaata gaagatagga
    55561 tggggaaact cttgaccaga gggtttcata tcctttttgt gaaaagaagt ttatactcaa
    55621 tgaaaatcaa agagcaaact aggaagctag ccgcaggctg ctcaaaacag tgttttgagg
    55681 ttgt
//
LOCUS       DAVMCN010000008        54304 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVMCN010000008 DAVMCN010000000
VERSION     DAVMCN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.008"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..673)
                     /locus_tag="VYP85_000611"
     CDS             complement(<1..673)
                     /locus_tag="VYP85_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881162.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFT"
     gene            complement(683..1435)
                     /locus_tag="VYP85_000612"
     CDS             complement(683..1435)
                     /locus_tag="VYP85_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881163.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(1435..2199)
                     /locus_tag="VYP85_000613"
     CDS             complement(1435..2199)
                     /locus_tag="VYP85_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881164.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(2295..2698)
                     /locus_tag="VYP85_000614"
                     /pseudo
     CDS             complement(2295..2698)
                     /locus_tag="VYP85_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2878..3510)
                     /locus_tag="VYP85_000615"
     CDS             complement(2878..3510)
                     /locus_tag="VYP85_000615"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1881165.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(3544..4245)
                     /gene="pyrF"
                     /locus_tag="VYP85_000616"
     CDS             complement(3544..4245)
                     /gene="pyrF"
                     /locus_tag="VYP85_000616"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1881166.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(4478..5698)
                     /gene="divIB"
                     /locus_tag="VYP85_000617"
     CDS             complement(4478..5698)
                     /gene="divIB"
                     /locus_tag="VYP85_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1881167.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVTSSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLFVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            complement(5708..6766)
                     /locus_tag="VYP85_000618"
     CDS             complement(5708..6766)
                     /locus_tag="VYP85_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1881168.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(6768..8120)
                     /locus_tag="VYP85_000619"
     CDS             complement(6768..8120)
                     /locus_tag="VYP85_000619"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1881169.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALVKGIPVLTE
                     VELAYLISEALIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGAFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(8224..8865)
                     /locus_tag="VYP85_000620"
     CDS             complement(8224..8865)
                     /locus_tag="VYP85_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881170.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSIFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(8867..10888)
                     /locus_tag="VYP85_000621"
     CDS             complement(8867..10888)
                     /locus_tag="VYP85_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1881171.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTSEVFEQELENFANSEQSLIARRIVEPSKDGTTHFIYATYGQGTLPKEFQEASQ
                     ENRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDIENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKVGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(10959..11258)
                     /locus_tag="VYP85_000622"
     CDS             complement(10959..11258)
                     /locus_tag="VYP85_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1881172.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSFIVSRWNGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(11622..11876)
                     /locus_tag="VYP85_000623"
     CDS             complement(11622..11876)
                     /locus_tag="VYP85_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1881173.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(11896..13737)
                     /gene="typA"
                     /locus_tag="VYP85_000624"
     CDS             complement(11896..13737)
                     /gene="typA"
                     /locus_tag="VYP85_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1881174.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQETTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            13899..14624
                     /locus_tag="VYP85_000625"
     CDS             13899..14624
                     /locus_tag="VYP85_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV1881175.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(14664..14891)
                     /locus_tag="VYP85_000626"
     CDS             complement(14664..14891)
                     /locus_tag="VYP85_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881176.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(14980..15360)
                     /locus_tag="VYP85_000627"
     CDS             complement(14980..15360)
                     /locus_tag="VYP85_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1881177.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(15360..15629)
                     /locus_tag="VYP85_000628"
     CDS             complement(15360..15629)
                     /locus_tag="VYP85_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1881178.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            15693..16601
                     /locus_tag="VYP85_000629"
     CDS             15693..16601
                     /locus_tag="VYP85_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1881179.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(16655..17410)
                     /locus_tag="VYP85_000630"
     CDS             complement(16655..17410)
                     /locus_tag="VYP85_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1881180.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(17431..18360)
                     /locus_tag="VYP85_000631"
     CDS             complement(17431..18360)
                     /locus_tag="VYP85_000631"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1881181.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQNLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(18375..18998)
                     /locus_tag="VYP85_000632"
     CDS             complement(18375..18998)
                     /locus_tag="VYP85_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1881182.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(18991..20229)
                     /gene="hflX"
                     /locus_tag="VYP85_000633"
     CDS             complement(18991..20229)
                     /gene="hflX"
                     /locus_tag="VYP85_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1881183.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMKELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIAFMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESITFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(20222..21106)
                     /gene="miaA"
                     /locus_tag="VYP85_000634"
     CDS             complement(20222..21106)
                     /gene="miaA"
                     /locus_tag="VYP85_000634"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1881184.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVSHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            21227..21397
                     /locus_tag="VYP85_000635"
     CDS             21227..21397
                     /locus_tag="VYP85_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1881185.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(21445..22284)
                     /locus_tag="VYP85_000636"
     CDS             complement(21445..22284)
                     /locus_tag="VYP85_000636"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1881186.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(22381..23340)
                     /locus_tag="VYP85_000637"
     CDS             complement(22381..23340)
                     /locus_tag="VYP85_000637"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1881187.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(23467..24465)
                     /locus_tag="VYP85_000638"
     CDS             complement(23467..24465)
                     /locus_tag="VYP85_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1881188.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(24515..25132)
                     /locus_tag="VYP85_000639"
     CDS             complement(24515..25132)
                     /locus_tag="VYP85_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1881189.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(25133..26854)
                     /gene="pabB"
                     /locus_tag="VYP85_000640"
     CDS             complement(25133..26854)
                     /gene="pabB"
                     /locus_tag="VYP85_000640"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1881190.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(26923..32586)
                     /locus_tag="VYP85_000641"
     CDS             complement(26923..32586)
                     /locus_tag="VYP85_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1881191.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDPTKYTDEET
                     VLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTTVETR
                     EEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAPTITETVIE
                     KPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSIKVALKDNT
                     GTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKEVQLDLKKV
                     EIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLAITNIEEVT
                     EEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDLVDAMQKNP
                     NGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFDRVEGGSIK
                     NINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDKLDDAGIMT
                     NVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIVGHLAHDFN
                     PRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKRGDIFFGSN
                     DMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMGITADTFEV
                     TEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQGNKLTTDS
                     PLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVKQVKEYSVA
                     ELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVNAIKNLYLE
                     ESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGLTYLNRYYG
                     VKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFREVVAKNTLS
                     GNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYRLYEGLNNG
                     QHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRETFKSEINKRAKEQVN
                     YLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPDYAPIREFF
                     GRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETTHVNDRMAY
                     LGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQWYNPDPTKL
                     QTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRPMDRNKLSG
                     PHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTAYVNVNMMA
                     GIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKENNGLLGDDF
                     IIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKTMFDEAVTK
                     DLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(32608..33171)
                     /locus_tag="VYP85_000642"
     CDS             complement(32608..33171)
                     /locus_tag="VYP85_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1881192.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(33287..34978)
                     /locus_tag="VYP85_000643"
     CDS             complement(33287..34978)
                     /locus_tag="VYP85_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1881193.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLNQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(34975..35712)
                     /locus_tag="VYP85_000644"
     CDS             complement(34975..35712)
                     /locus_tag="VYP85_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881194.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(36025..37137)
                     /gene="msrB"
                     /locus_tag="VYP85_000645"
     CDS             complement(36025..37137)
                     /gene="msrB"
                     /locus_tag="VYP85_000645"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1881195.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(37148..37714)
                     /locus_tag="VYP85_000646"
     CDS             complement(37148..37714)
                     /locus_tag="VYP85_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1881196.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(37734..38444)
                     /gene="ccdA2"
                     /locus_tag="VYP85_000647"
     CDS             complement(37734..38444)
                     /gene="ccdA2"
                     /locus_tag="VYP85_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1881197.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(38655..39515)
                     /locus_tag="VYP85_000648"
     CDS             complement(38655..39515)
                     /locus_tag="VYP85_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1881198.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(39699..41753)
                     /locus_tag="VYP85_000649"
     CDS             complement(39699..41753)
                     /locus_tag="VYP85_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1881199.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLIWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHSFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(41765..42019)
                     /locus_tag="VYP85_000650"
     CDS             complement(41765..42019)
                     /locus_tag="VYP85_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881200.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(42012..42569)
                     /locus_tag="VYP85_000651"
     CDS             complement(42012..42569)
                     /locus_tag="VYP85_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1881201.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(42553..43509)
                     /locus_tag="VYP85_000652"
                     /pseudo
     CDS             complement(42553..43509)
                     /locus_tag="VYP85_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            43601..43960
                     /locus_tag="VYP85_000653"
     CDS             43601..43960
                     /locus_tag="VYP85_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1881202.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            44172..45021
                     /locus_tag="VYP85_000654"
                     /pseudo
     CDS             44172..45021
                     /locus_tag="VYP85_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45269..51970)
                     /locus_tag="VYP85_000655"
     CDS             complement(45269..51970)
                     /locus_tag="VYP85_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1881203.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TQKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLNFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKTLRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSDLPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGYVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(52172..52249)
                     /locus_tag="VYP85_000656"
                     /pseudo
     CDS             complement(52172..52249)
                     /locus_tag="VYP85_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(52275..53750)
                     /locus_tag="VYP85_000657"
     CDS             complement(52275..53750)
                     /locus_tag="VYP85_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1881204.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(53798..54103)
                     /locus_tag="VYP85_000658"
     CDS             complement(53798..54103)
                     /locus_tag="VYP85_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1881205.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIESAIKEHGLS"
     gene            complement(54141..>54304)
                     /locus_tag="VYP85_000659"
     CDS             complement(54141..>54304)
                     /locus_tag="VYP85_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1881206.1"
                     /translation="VSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKL
                     YAYIAEATA"
BASE COUNT        15837 a        11965 c         9942 g        16560 t
ORIGIN      
        1 gagtgaaata gaaaatgctt ttaaaaagaa agactaaaaa tagcaactga agaaataaat
       61 ctcgtcctat atctccattc cctcgattca aaatataaaa tagataatta gttcgatttc
      121 ctacaaatag accaccaaac acaatcatga gtaaaaagaa actaacgcaa gcaaagttca
      181 tttgtacatt cgctcctagt gcgtataaca taaagcaaag caaggatagc acacaagcat
      241 tcaaagaatc aactataaac aaaactccta tatcccagtt tgctaactgt aacataaatt
      301 gaatcactag aacttttacc atgattaaaa tgagtccata aagaaaacag gtccaaatct
      361 gatacctaat ccagagctta atagaagaaa atcgaatcac ttccataaag aaatcggatg
      421 ctcttctacg atatacaact gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc
      481 atatagataa gactaaaaaa gagttttgac tcagattagg cccttttaaa atttctataa
      541 caagtctatc atttccttct aaccaatacc ataatcctaa acaaatcaat atccaaaaaa
      601 gaacataacc ccaaaagtac ttggtataga ttatctgatt caacctccac atgtgactac
      661 ttaactttcc catttccaac ttttacactc tcctccagtt tctatgaaca gaaaatacag
      721 tcaatggaat tatgatagat agtaatgtaa gccaataaat caatgcatac ggattggaat
      781 ttaccatata ctgaaaaatt ggcaataatc caattatccc attgttcaac tgataaatcc
      841 agaataagga ttctacaaat aaaaaagtaa acagaaatac taagctcatg tttgattttt
      901 taaaccaaga aaaactgcta atagtaagta aggataaaaa gaaatagtat gctatataag
      961 agaaaaaaaa tcctataaag aaactagcat tgtttgcaat acttatacca taaaattctc
     1021 ttaaaaaatc aacctccttt atctccaaag agaagctaaa accattacta aatgcaatta
     1081 gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt actaagagct gctaatttga
     1141 aactaaaact ggtaaagtgc ttaattgatt tcagacgaat gcgacactcc aacctattaa
     1201 aatagttatt catcaaataa aaaaagaaca atatatatgt gaacggaaag caatatactc
     1261 cagtcgtcat atcttgaagt aaaactaaaa tccattctaa tacatttgga tggattgaat
     1321 attggcgaca gcgcaataaa tatactgtac tagataaaac acaggatagc agtaatataa
     1381 aataaaccaa tactgctaag aaatcttttt tataaaattg aacaaattgt ttcattatac
     1441 atagtcctct gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa caaataaaat
     1501 aaaagcaaga tgcccactaa ctaaggaaag actgatatct ttctgatatc ccaaagctag
     1561 cgttgtcaca ggttctaagt aagatagccc taaaatagcc cataaaatac caccaaccat
     1621 catataggca actgggatga aaatagctcc taattttttc ttcactagca aagcactagc
     1681 tagtccaaaa atagagaaca cagcgcccca aactccatac cagagagtcg tcacaagact
     1741 atagagaaac tgattagaat caaataattc ttttaaggca ccactataat ctccaatata
     1801 aatttcctga taaggagtca ctaaaagatt aattcctaat aataataaat aggggagaaa
     1861 aaagactaga aaagaagaaa taattgcagt actacctaca atagctagat acctcttttt
     1921 agaaattcgg cacaattgtg ctgttagaaa atgactctca gcatcctcta ttatctgact
     1981 agaatagggc agtgtacaga taagtgcagc tactaggcta atcggtgaaa atcctcgaat
     2041 agaagaagcg gcaaaaaaaa tcgataaacc ttcaatttta taaataccat tgaaagcaag
     2101 gaaatttcct aaactcatgc aaagaagggt caaaaataaa gacatataaa accgaggtga
     2161 ttgaacgact cgtacaagat tacaaatgaa aaattccatc cttactcctc cttataataa
     2221 aaatagggtg tagcattctt ttttcatgct acacccacaa tcaaccatct ttaaggctta
     2281 ctctgacaag taagttaata agaatctgga ctccaagaac ctgaagtatg aattcttaca
     2341 tgatttccaa attgtggcgc catagctaat ctagtaccag aaccaatata attgtcacca
     2401 cctccattat agtacatgac aatcctagag ccagacccca atgaatatac cggggtaata
     2461 tctgacccac tataggcgct acgaatagag gtatttaacc ttttaccgcc accagtgctg
     2521 tcactattat taattccagc agaggcgttt tctttctcaa gctcactagt tgtatccgaa
     2581 ccccaacgcg gcaacgttaa atcataattt ccaatctgtc tagctaaaac tgtagggaga
     2641 aacaaactag atgcaattgt aactacgcaa aaaaggaata tatttttctt cttttcatga
     2701 catcgtcctc ttaagaagtg ataaacaaga tagttgattg atcaatttga tacatattac
     2761 attttcatta tatcaataaa agaaagcgtt gtcaattatt ttatttaaaa tattatcata
     2821 ttttaaataa aatggtaaaa gagactcggt agcctcgtct ctctttatct tactgaccta
     2881 accttcttgc caattttctt ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg
     2941 cgtgatgtaa ccttcttctt gggctagatg gataagctcg ctatagtttg aaagcgtcac
     3001 aagtttaaca ccagcatctg caaagttctt atctgctttt ggcaattggt agctgaaaat
     3061 cgctacaact ccaagtacat ctgctccttc tcgcttggct gctgctacag cttcaagaac
     3121 tgaaccaccc gttgaaataa ggtcttcaac cactaccatt ttttgacctt gagctacgcg
     3181 accttcgatt tgattaccag ctccgtggtc ttttggtttg ctacggatgt aggcaaaagg
     3241 caagtccatc ttatcagcaa taatggctcc gtgtggaatc cctgctgttg cagttcctgc
     3301 aatcacttct acttcaggaa aggcttcttt gatagcttcc acaaaaccat tttcaattag
     3361 ggtacgagtt tctggatagg ctagtgtcac acgattatca gtgtaaatcg gtgacttgat
     3421 accagacgcc caagtgaagg gttcctctgg tttgaggtaa acggcttgga ttttcaagag
     3481 gtggctagcg atatctttag caagtgtcat ggtattctcc ttttattttt ctaatctagt
     3541 tctttaattc cagtcctgtg tccattcatc cttgatggca tgataagctg caacaggatc
     3601 ctcagcttgg gtaatgggac gtcccactac gatatagtca ctaccaattt gataagcatc
     3661 tgctggcgtc atgacgcgtt tttggtctcc aacagcagct ccctgtgggc gaatccctgg
     3721 tgtcagacag ataaaatctg gattggtggc ctgcttgata agttgaactt cctgtgccga
     3781 gcaaacgaca ccatccaagc ctgcttcagc tgtcttcttg gcatagtgga tcacagactc
     3841 ttgtaggctt gtttggatat tttgaaactc ctgcatctgg gcttctgatg ttgatgtcag
     3901 ctgcgttaca gcgatcaatt ttgcttgact tccaagacct tcacgcgcag ccttcatcat
     3961 ctctacacca ccagccgcat gaacattggt catatcgaca ccaagctgag acaagacctt
     4021 catggctgac ttgactgtat taggaatgtc atgaagtttg agatccaaaa agacactatg
     4081 acccaaacct tttaagtagg acacaatctc aggccccgct gcgtaataaa gctccatccc
     4141 taccttgaga taaaggcttt cttctgctgg gaaaagagct aaaaattcct tgaccgcctc
     4201 aaaactagga aaatcaagag caatgattgg acgatgttct cgcataggtt tctcctttta
     4261 cctttactag tgagagagtc tggccaacag aagccacgaa aaaaggaacc tgccaacagc
     4321 aaggttccac gaaaaatggg tagtctccac cctttcaccg tctaacctta gctgcctctc
     4381 tggactgctt taaaggtttt ttactattct attatttcta ctagcacttg tcaagtaaaa
     4441 acttagtcac taaagaacta taagagaaaa ggtaaaccta gcgacgcgat gagcgctggg
     4501 tcgtttggtt tcgattgctc tcttcctctt gttttttctg ttcttcttct aaacgtttct
     4561 gttcttcttc ctgttttttc tcagcttcct tggcctcttg tttggctttt tcctcagcct
     4621 ccataattaa tttatccgcc acagtgtagc tgtagattcc agcttccatg tcgaccacac
     4681 tcggttctga caattgaggc ttaatcttac tgtaatatgg cagtttctta ctcatttcag
     4741 atagaggaac caagacttcg tccgaatcat tcatggtcaa tcgaattaaa tcggatgtca
     4801 ccttgcttgg ggctaattcc accttttgga tagccgcctt gagttctggg ctaatttgag
     4861 caagttctga gacaaaaacc ttgatttgtt cactatcatt aaagagaact gataaataag
     4921 tttctggtaa actgttcaga ctcacagaac tagtctcaag ctgaccactg gaaagaatag
     4981 gataatgatt ttcaccagaa atatagtagg ccacaatatc atattccttg accttaatag
     5041 tgaacttagt tggaaattga tagacaagtt gagctgattc aacccaatag ttagacttaa
     5101 tctgcttttc atattttgcc ttgtctagca gaaggttaat cgtataatcc gaatcctgaa
     5161 tgcctgaagc ctgtcgaata tcatcagctg tagtttgcac cgttccctca acacgaatat
     5221 ctttcatggt cgcataagga ctgagcaagt aggcagagac aaacaataaa agcagacttg
     5281 gaaataaaat cgtgaaggct cgcaagatat ggataccagg aatctttgct ttggctggtt
     5341 tttcctttgt agccttttta gaaagctttt tatcctgttc ctccttctct ttagactctg
     5401 gttcttcttt ctcttctttc tctttgtcag cctctgagga tgttactttt tcttcagact
     5461 cttccttagc tgattctgaa tcttcctggt ctgtttcact ctcctggtcc tgtttatcct
     5521 ctgacttctc agattcttct cccattcgag cttgtctttc cttttccttc tcctcagcta
     5581 gagccgcctc ttcttcagcc ttctttttta gatattcttg gtttcgtttc tgccattctg
     5641 ataactcttt caattcttcg aggatttctt tgtcctcatt tttcttatct tttgacattt
     5701 actttcctta tgataaatct tttttcaaca attgataaaa atctgctaga gatttcaatt
     5761 ccttagaagc tttcatctta gcttggtaat cttccttgtg acttagtaag tgagaaagct
     5821 tctcttccaa actatccaag gtcaaatcgc tttcttgaag gtcttctgca tagccttttt
     5881 ttacaaagta agctgcattt tcaatctggt caccacgact agcttcacga ccaagcggca
     5941 caatgacatg caattttgct atcgccaaga gctcaaaaat cgtattggca ccacctcgtg
     6001 tcacaacaat atcagccaat tccatcaagg gttgatagag atcggtcaca tagtcaacac
     6061 gaaaaagatt ttggctcaac tcattcaggc tagaatctcc agttagattg ataatattgt
     6121 agcgctctgt tagttctttc ttatggtctg tcaccaattg gttaaagaca cgagcacctg
     6181 cagaaccgcc aacaaacaat acagtcggca atttatgatt aaagtgggtt tgaatatcca
     6241 ccaattcatc tggttctgga tttttttgat ctgaaacctt ggtcactgct cccacatgct
     6301 caaccttaga caaactcgaa gcttgctcaa aggttgaata catcttagtc gcaaatttat
     6361 aggcgatttt attggccaag cccatagaca ggtcagattc gtgaataaag acaggcactc
     6421 ctgacacacg cgctgcgata acaggcggta ctgagacaaa gccccccttt gaaaaaaggg
     6481 tctgtggacg aagtcgcaac atgataaaga gcgattggac gattccccag ccaactttga
     6541 agacgtccag catattttgc caagagaaat agcgacgcaa ttttccagtc gcaatagaat
     6601 ggaaggtgac atccaaacct gacttaagga tttcttggtg ttcgatacca cgcttgtccc
     6661 cgatatagtg gacttcccaa ccatcttcga tgaacttggg cattaacaaa agattgaggg
     6721 taacgtgtcc aaccgtcccc ccacctgtaa agacaatttt tttcatatta ttcttttaac
     6781 tccgctactg tgtcgataaa gaggtcgcca cgtacttcaa agttagcata catatcccag
     6841 ctggcatttg caggactaag aagaaccaca tctccttgag tcgcaagctc ataggccttg
     6901 cgggtcgcat ctgcaatatc tgtcgcctcc acataagcga caccagcctt gtctgctgcc
     6961 cgtttgacac gttctgcaga ttgacccagg atgaccatct tcttgagtcc agtaatgtct
     7021 ggcaccaatt cgtcaaactc attgccacgg tccaaaccac ctgcaatcaa gacgaccttg
     7081 ctgttgtcaa atcctgacaa ggctttttga gtagccaaga tattagttga tttactgtcg
     7141 ttatagaatt taacaccctt gatgtcatcc acaaactgga gacggtgttt gacaccaccg
     7201 aaggctgaaa gagtttcctt gatggtttga ttgtccacac cacgaagctt ggctacagca
     7261 atagtcgcaa gggcattttc cacattgtgg ctacctggaa caccgatttc attcgctgcc
     7321 atgactactt caccacggaa gtagagttga ccatcttcca gataagctcc atcaaccttt
     7381 tcaagtgttg aaaatggtac aacagtggct tctgtcttgg aagccaagtc ttttgccaag
     7441 tcttgattaa agttcaagac aaggaaatca gctgctgtca tcttgttctg gatattccac
     7501 ttggctgcta catattccga aaatgcccca tggtagtcga tatgagttgg catgaggttg
     7561 gtaataaccg caatctctgg atggaattct tgaacaccca tgagttggaa agaagaaagt
     7621 tccataacaa gcgtgtcctt atctgatgct atttgagcaa cctgactggc aggatagccg
     7681 atattccctg ataaaagacc atgttgccca gcagcagtca aaacttcccc aatcatagtc
     7741 gttgtggttg tcttaccgtt cgatcctgtg ataccaataa tcagtgcttc tgaaatcaaa
     7801 taagccaatt ccacctcagt caagactgga attcccttga ccaaagcctt ttcaatcatg
     7861 ggattgctgt aggggatacc tggatttttt accatgaggg cgaactcttc atccaagagt
     7921 tccaaaggat ggccacctgt aatgaccttg atcccttctt ccagcaaact ttgcgcagct
     7981 ggattgtcct cgaatggttt cccgtcattt actgtcacta tggcgcctag cttatccaac
     8041 aaacgagctg cagattcacc agacttggcc aaacctaaaa caagaacttt cttattttta
     8101 aattgatcta ttactttcat gtctcgaact ccatttctac tcctactatt ttaccatttt
     8161 tatggaaata aaaaagccac aaagtgtgtt tgtgactctt tcttctaact gaatcttacc
     8221 atatcatcta tgtgataaat cggtaactcg aatgacctga tccacttgct cccaaatcag
     8281 aggattgtgg gtcgcaataa taatggtccg attcggattt tttaaagatt ctaggatgga
     8341 aagtaattcc tcagagtttt tggggtctaa ggaagcggtt ggttcatctg cgaggatcaa
     8401 aggtggatcc tttaaaatta tcttcgctaa tgcaacacgt tgtgcttctc ctcctgataa
     8461 ctcaaatata ggttgcttca aatccaaata agagaggttt acacggttta gagcttgttt
     8521 catcaaagag attttctctt tttccttcaa ctttttacca actaaaccca gattgagatt
     8581 ctctttgacg gtttggcttt caattaagcc aaaatcttga aataagtatc ccaagtaatc
     8641 tctaaagaaa atagaaggct tgatgtcctt aagagaagtg ccatcataga tgatttgccc
     8701 tttgtcatat ggctctaatc gtccaatcat attcaagagt gttgtcttac cacagccact
     8761 tgtaccgatt aaggcataaa ttttcccacc ttcaaaatga agatttgtat ctgaaaatag
     8821 ctgacggctt ccaaattttt tagatatatt ctttagttca atcatcctat tttcctttca
     8881 taattgtcat agaaacacga gattctttct gcgcttgacg gtaaagcgtc agaactgcac
     8941 tagctagaaa gactaataaa gtgagcaagc caatcaccaa gtctcgactg cttaaaataa
     9001 agagactagc accaaataca aaactggcaa attgactaac catatactga gcatgtgttt
     9061 caaaaaatcg taaacctgaa attcgtttaa tcaagatatc tcggcggaat tgctcgaaat
     9121 atagaagatt gacagaataa aatagtaata aggaactagc tatccccaca atagctccta
     9181 agattaaagt tgctgtttca gtttgaactt cattataacg agttagataa acacttcttc
     9241 cttctttaag ataggatact tgctcataaa ttccaacttt cttcaagagt tctagcccac
     9301 tctcatatcc tttgataaag agttgttttc cagcattgat agaccaacta gataaggata
     9361 taaaactatc acctgtagaa gtcggcgtga ataccactaa aatcggatca gtcaaatact
     9421 gagtggatac gggattctca ccgttattat aaacaaaccg cttttctccc attgaaagat
     9481 aactaacgtg cgctttcatc tcataatcca aaggagcact tgcctcctca ccagattttc
     9541 cataataact caatctttct tcaaaaactt tcttaagttc tgcttctcga gagcgcaaat
     9601 gttctgggag caagaggata aactcacctt tttggagatg ggctaacttc tgtttggtct
     9661 cagcatctac cacgaccttt tccttgtcca aataactagg actaacatag agcgtattag
     9721 catctggact ataggtatcc agtgtctctc cctgttcatt ttttccttgt ggattggcaa
     9781 aatggagcag attatccttt acataaagag cttgttcttc ttcgattgct tccttggcaa
     9841 aggcatacca cttgctctga ttttctatat cttttcctct atcacctaag ccaaaagaaa
     9901 tttgataata gtctgctcta tcctgccatg cttgttttga aatttcaagt tctttcaatc
     9961 gttggtaaga cgtcaaacct gtcttaacag cgtatcctac tgtaaagaca gcaaccaact
    10021 gacacaatag ggttaaaatc atcaggcgtt taaggggtaa tctcccctta ataacgggaa
    10081 ctaatgcttt gtaattcaaa ctcattagat aaaggagcat tagtaaaatt gaaatcgcca
    10141 ataaaaacaa cagatagaaa ctaatcccaa aaccataggt ggctaacaag ataggataaa
    10201 acaaaccttg actaaaaaga acgactcccc cacctaggaa ggaaaggagg gctgatagaa
    10261 ggagccattt gatatcagta gataaagaat gccccatgat ggataagaga gtctgaccag
    10321 aaaagagttt tatacctgct gctctcattt ccttaatccg agtgataatc actaaagcaa
    10381 agaaagataa gccaaatatt gctaaactaa ttaaaataag gggatttagt aatattcgaa
    10441 aagcaagaaa atagggcggt atctttcggt cagcacttgc tttataaccc aaatctccta
    10501 atttatcggc aagcttttct ttcgtcaagg agcctgacaa aaggagataa ctatttagcg
    10561 gatcactacg ttcacgattt tcttggctag cttcttggaa ttcttttggt aaagttccct
    10621 gaccataagt tgcataaata aagtgagtcg tcccatcctt actcggctct acaattcttc
    10681 tagctattaa actctgttct gagtttgcaa aattctccaa ttcctgttca aatacctcac
    10741 tcgtcggttc ctgagtatct tttttgacac gaagtaaaga aacggaatca tagcttgcat
    10801 ataaatattg tggcgcacgt aagacaataa tccaagcaag gaagaagctg agaaaaaaag
    10861 ttgataataa tatgaatagt ttcttcatag tagactcctt gtaaacaaaa ttccccctgt
    10921 aatttcttac aaggggaacg atttaaatca atgaacgatt agtcataatc acagtaaaat
    10981 gctacttgtt ctccccattt agtccaaatc catgcatagg aggtttttcc agcaggagct
    11041 tctcctttat cagaatgacc attccatctg ctcacgatga atgaataatg atatttttta
    11101 ccatgatagt aatttgaaaa agcccaacca cctcctgaac cttctccata tgtccatact
    11161 cctccatctg gatattgtac agcagctgat gcagctccca ataatgtaaa acttgaaata
    11221 agagctagag caagtaatct atgttttttc gttttcattt tattttttct ttcaaaaaaa
    11281 gcacaccctg agcaacaatg caacaaaata aatcctcctc tctcttttat tgaaaccgct
    11341 ttcttatgtg ataagaataa catttttatt atttgttgtc aaggaaaaaa tcgaattttt
    11401 tagatgtttt actatattat ctctatgaat aatattatat agtagtttta tttcaaaata
    11461 atatgcaacc agtactaacc aaatataaaa tagatgccat taacgaattt tattcaagtt
    11521 tttcccattc atactataca agcaaaagag atggtgttaa ctaaaaagca attcaaacta
    11581 ttataaaatt cctagcaaaa agagagccga aactctcttt tttatcttct tttacttttt
    11641 ttgactggca tgagtgtgat gtctctaaca ctaaagtaag ctaggatcaa catggctatt
    11701 gctaggaata tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc
    11761 aagagtgcca ctaaaataca taccatagcg acgatattga ctgtcccttt aatgctttct
    11821 ggtgtcgcaa atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt
    11881 ctctctttct agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc
    11941 tttgttaagg atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc
    12001 gtcgttcaag aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc
    12061 tgtttggtcc ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac
    12121 tgtcaagtca ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc
    12181 tgggttgaca aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt
    12241 accagcatcg atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa
    12301 tggcaagtat tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgataagaa
    12361 ctcagttgag tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc
    12421 attaccagtt gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac
    12481 agacccttgg tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac
    12541 accgtcgatt tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg
    12601 acgcattgtt tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt
    12661 atctggtgaa tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa
    12721 gcgttcttcc accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt
    12781 gttgaccaag aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc
    12841 tactgcatct gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc
    12901 aatcaagtca cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa
    12961 gagttttgta acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc
    13021 cccaacctta actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt
    13081 gtagtccaaa agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg
    13141 gatatggtcg ataatcgtgt caaagattgg tgccatagtc gtttcttggt cagctggatc
    13201 atctgacaat gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg
    13261 atcgtcatct gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg
    13321 acgagctgat ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa
    13381 ggcttttttc aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa
    13441 gacaacaccg tcaaccattt tcatgatacg ctcaacttct ccaccgaagt ccgcgtgtcc
    13501 tggtgtgtcc ataatgttga tacgagttcc gttgtaagca acggcagtat ttttagcaag
    13561 gatggtgatt ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc
    13621 agtacgtgca tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc
    13681 gtggtcaacg tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat
    13741 ttcctctata atattcaaaa tttattttct aactgaacga ttataccata atttcaaata
    13801 aataacataa ctcaagcaag tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc
    13861 ttttcaaagc aagcgactta tgataagata ggcacagtat gcgtttagat aatttattag
    13921 ctcaagaaaa aatcagccga aaggccatga aacaagcctt actcaaaggg gacattctag
    13981 tcgatggttg cccagcccgc tccctagctc aaaatatcga tacaggacta caagaactcc
    14041 tttttcagga tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg
    14101 ctggtgtcgt tacagccaac aaagacaagg aacttccgac cgtcatggac ttgcttccat
    14161 ctgacatcca gtctgacaag ctctatgccg tcggccgact ggaccgagat acaacaggac
    14221 tccttctctt gaccgataac ggtcccttgg gcttccaact cctccatccc caatatcatg
    14281 tcgataagac ttatcaagtt gaggttaatg gacttctaac acctgaccat atccaagcct
    14341 ttcaaaaggg aattgtcttt ttagatggta ctgtctgtaa acccgcaaaa ctagagattc
    14401 tatctgcaag tccctccatc agtcaagcct ctatcaccat ttcagaagga aaatttcatc
    14461 aaatcaagaa aatgttcctc tcggttggtg ttaaggtgac tagcctcaag agaatccaat
    14521 ttggggactt cacattgaac ccagatttag cagaaggtaa ctaccgccct ttgaaccaaa
    14581 aagagttaca aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta
    14641 aaactaaagc ttttttcttt tatttatcga aaaattaagg cgattgctac aatccagtta
    14701 actacagaaa tcacaattcc taagatatta agaatctttt ctattttata gtctaattgt
    14761 gactcttttt ggtatgaaat agccaagacc aatcctatga tacccaaaat caggcctaca
    14821 attggaaata acaaaccaag aataatcgac aagataccca caaaaagtgg atttttcttc
    14881 ttttctttca tgttctaaga actctttaaa ttttatacaa attaattata ctataaaaca
    14941 atagcttcat cctatcattc gactaatttg gaaataaggt tagctagtct tcactttccc
    15001 tttccaagaa tccaagccat aagaaaggat ataaatctca gaaaaacctt gttttttcaa
    15061 gtaaagagct gcatttgtaa ctcgttgcgc acgttggttc tcgtagagaa ggacaggttt
    15121 atctttacga agggctgcaa gactagtttt caactgactt gaaggaatat tgcgtgcacg
    15181 aaggatatgt tttctgtgga attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg
    15241 aatcaaggct tcaaactcct cattgtccac aattttagcc gcacggcgaa tacgaagata
    15301 gttaaagccc atccacgcca acattgctag tataagtgcc cacaaaatcc aagtaaccat
    15361 tagttctttt ctccattttt ctcaatataa tccaattcta ccttgtgctc tctgcgaaga
    15421 actgcttctg cctctagata gtctaattta tccatcaacc ctgcatcgta aatccgagat
    15481 agttccaact tcatcagttc aatatcatat aagcgttttc ccatgtaaac aataatacca
    15541 aatcgtttga ggaattgttg cacatcatag aatgttttca taagactcat tctagcaaaa
    15601 ttttgtgttt ttttcaagaa gagactcaca caatgctcct tattttccta tcttctttag
    15661 cgattctaag gcaagtgtgg tacaataaaa acatgagaat tcaacaatta cattatatta
    15721 tcaaaatcgt cgaaactggc tccatgaatg aggcagccaa gcaactcttt atcactcagc
    15781 caagtctttc caatgctgtg agagatttgg aaaatgaaat gggcattgag atctttatcc
    15841 gcaatcccaa gggaatcacc ttgacccgtg atgggatgga gtttctctct tatgcccgtc
    15901 aggttgtcga gcagacccag cttctggagg aacgctataa aaatcctgtc gcccaccgcg
    15961 aactctttag cgtttcgtct caacactatg cctttgtggt caatgccttt gtctctttgc
    16021 tcaagaaaag cgatatggag aaatacgaac tcttccttcg tgaaactcgg acttgggaga
    16081 ttatcgacga cgtcaagaac ttccgcagtg aggtcggggt cctcttctta aacagttaca
    16141 accgtgatgt tttaaccaag atgctggatg acaatcacct gctagcccac catctcttca
    16201 cagcgcaacc gcatatcttt gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga
    16261 aactgtctga tttggagaat ttcccttacc tcagctatga ccaagggacg cacaactcct
    16321 tctacttttc agaagagatt ctttctcaag aacaccacaa gaaatccatt gtggtcagtg
    16381 accgtgccac cctctttaat ctcttgattg gtttggatgg ttataccatt gcgacaggga
    16441 ttttgaacag caacctaaac ggagacaata tcgtttctat cccactggat attgatgacc
    16501 cgattgagct ggtctatatc cagcatgaga aaaccagcct atctaagatg ggcgaacgct
    16561 ttatcgacta tctactagaa gaagttcagt ttgatagttg agaaatgata agaaccaata
    16621 tgtaggctag caacaacctg cacattggtt ctttttactt ataattaaaa gtttcccctg
    16681 ccaacttatc agctagcttg ggaaagagag tataaaactt atgggctagg ttcaacaaaa
    16741 tcgggagatt gagttctcgt ttatttttgc ctataatctt gacaatcttt ttagccactg
    16801 catctgcctc taagaggaag cggtcaaccg atttaagata agttccatct gggtcagctt
    16861 ggtcaaaaaa tcctgttcgg attggacctg gattgactgt tgtcacatag actccatagg
    16921 gcataagttc gagtcgcaga gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt
    16981 aaagactaga cttgccagta gctattagac ctgccatgct gacgatgttg atgatatgcc
    17041 ctttgctgct ttccttcata cgagccgcaa ggtgacgaga cagattcatc agggcaaagg
    17101 tattgacctc aaacatctgg tgaatatctt tatcagcaat ctggtcaaat ccctcaaaaa
    17161 tcccgtaacc agcgttgtta atcaagacat caatcttgcc atagcggaga taaagatcag
    17221 ttaccagagc ttctagggct gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg
    17281 aataatttcc gtagagttgg gctaattttt ccttatttct accaagcaag atgagttggt
    17341 cattgggcag gagtttgacc atttcttgag ctagaccacc gctagctccg gtaatgagaa
    17401 tagtaggcat acttatcctt tctgtgactg ctagatttcc acttcttcca agtctttgac
    17461 cacatggaca ttttcaaaaa ttgtggcagc gtccttcttg agtttgctta tatcttttga
    17521 gaggaaacgg gcactgatat ggttgagtag gaggcgtttg gcacctgctt ctaccgctac
    17581 ttgtgcagct tgcatattag ttgagtgacc atggttacga gcaatttttt catcaccctt
    17641 gccataagtg gactcatgaa ctaggacatc tgcattgaca gccagacgca cactggcatc
    17701 cgtttttcga gtgtctccta aaatagtgat aatcttacct ggacgtggcg ctgagatata
    17761 gtctgctgcc ttgatttcag ttccgtcttc caaaacaaga ttctggccgt ttttgatttt
    17821 accaaaaagc gggccgaacg gaacaccagc agccttgagt ttttcagcat ccagcgtccc
    17881 ttctagatcc ttttgcatga cacgatagcc aacacagaaa atagtgtggt ccagctcctc
    17941 tgcatacaca gtgaatttat cggtttcaag aattttaccc agagaatctt ggtcaaactc
    18001 atggaaatga atgcggtagg gcagacgaga acctgacaca cgaaggctgg ttaagacaaa
    18061 tgacttgatt ccttgaggtc cgtagatttc caaatctgtc tgctcttcat tggcctgaaa
    18121 ggcacggcta gaaaggaaac ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat
    18181 aaagattttg ctgaccttac gtggtcgaat tgtggtttcc agaatgcgat tttgcgtacc
    18241 ttctccacag tcaaagagcc aaacttcgtt aatctcgtcc aaaagtttca gggcgagact
    18301 tgaaacgttg cgagctttag agggctgacc agcccccgtt cctaaaaatt gaatatccat
    18361 tcgatacttt ctaattaatc aatatataac atggctgtgc ggttttccga tcggaaatag
    18421 cgtttgccag aaaaagcagc agcttcttgc aataaatcct cttggctgta gcctttgaga
    18481 cgttttcgac catcagccaa tctttccaaa tcagtcaaag ctgtgagact ttctaggctg
    18541 acaacttcct cgtcctcgac aggcttcatg taaatcttac cagactcttc aaagactagt
    18601 tgatggggga aaatttgcgc aatttcaaag agcaagtcat ccgatatttt ctcctcattt
    18661 tcagagaaaa tccgaccaaa gccgtcactc tcataacaaa aaccaaagga tttaccagac
    18721 agattaagcc gaataaaaga cttattttct agggtgaaac ttggctcagt attgtaaaga
    18781 ttcagttcct gactgagttc tgcaaaataa tccgtcgcag cctgaggact ttttttctga
    18841 tagagttctg caaagtaggc attaacaaca cttggcggag gtgtaataag tgttaactgc
    18901 tcctgctctg tcttaccagc tagaagctga tccagataga ccttgtccag acttgtataa
    18961 cctccatact ttagagccaa agttttaata tcagtcataa aattcttcta acctccattt
    19021 atttttctcg gaaatgtagc ctgtaatcac ttcgccgtct tcctgataat cacgttcttc
    19081 cagaattgca acactctcta aatcatgaat cttataggac tttgaaaaag gcactcgcag
    19141 ggtaaatgct tcaaaaattt ccttaatctt atctagcaat aatgcttgca agttttcacg
    19201 actgtcctca gacttggcag aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc
    19261 caccaaatcc gctttattat aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt
    19321 catgatggag agaaccgttt tttcatgttc ctcgtggtaa ggattgctag catcgataac
    19381 atgaaccaga aggtccacat gcttgctttc ttccaaggtt gacttgaaac tggacaccaa
    19441 ctctgtcggc aaatcttgga taaagccaac ggtatctgtc aaagttactt ggaggttgcc
    19501 tcccagatga atactcttgg ttgtcgcatc cagagtcgca aagagctcat ctgcttcata
    19561 ctgggtctta ctggtcaaga tgttcatgat agttgatttc ccagcattgg tataaccaat
    19621 caaaccaatc ttaaaagtga tagactccaa acgtttttct ctgacagtcg cacgattttt
    19681 ctcaaccacc ttgagctggc gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt
    19741 cagctccagt tggctttcac caggaccacg ggaaccaatt ccccctgcct gacggctgag
    19801 cataatcccc tgaccaacca agcgaggcaa gaggtatttg agttgggcta ggtggacttg
    19861 gagcttccct tcatggcttc gagcccgcat ggcaaagata tccaaaatca actgcatacg
    19921 gtcaatgacc ttaacaccga gaacttcctc tagattgaca ttctgccttg gggtcagacg
    19981 gttgttgacg atgacagtag tgatttcttc tgcatccacc ataaacgcaa tctcttccaa
    20041 cttaccagag ccgacgaagg tcttggaatc atatttttca cgtttttgtc tgtagctatc
    20101 tacaacgact gcccctgccg ttttcgctaa actagccaat tctttcatgg agaggtcaaa
    20161 actgtccata ccctgcaatt ccacaccaat cagcaggact cgctcctctt ttttctccgt
    20221 ttcaatcatc taaaaactcc tctatctggc ttaaaatgcg gtcttgtaca ccagattctc
    20281 caatctgata aaaggtgacc tgcatgcgat tacggaacca ggtcagctga cgcttggcaa
    20341 aacgacgggt cgcctgtttg agactctcac tagcttcctc caaggtctgc tctccacgga
    20401 aataaggaaa gagttcctta tagccaattc ctttagcagc ctgtacatta ggggaatggt
    20461 caaacagcca cttggcctca tccaaaagcc cagcctcaaa catcaaatcc actcggtggt
    20521 tgatacgctc ataaagttga ctacgttcat catccaagca gataatcagc ggttcataca
    20581 aaatctcttg attttccaaa tcctgaccaa aatgggcaat ttctaaggca cgcatagcac
    20641 gacgacgatt aaactgggga atctcaaggc ctgcttgatc caccaaatgg gctaattcct
    20701 catctgaata tggctccaaa ctagctcgat aagctaaaat ctcctcatga ggagtctccc
    20761 cacctaggtg gtaaccttct agcaagctct ggatataaag tccagtccca ccggcgataa
    20821 tggctagctt gccacggctg tgaatatcct caatagtcat cttagcttct gaaacaaaat
    20881 caaaagccga gtaagactcg gttatctctc taacatcgat taaatgatga gaaacagctg
    20941 cctgctcttc tggactagcc ttggccgtcc caatatcaag tcctcgatag acttgttggc
    21001 tatctccact aaccacttcg ccattaaaac gctttgcaac ttcaatagct agagccgtct
    21061 ttccaacagc agtcggtcca acaatcacaa ttatttttgt tttcatcttt tttccttgaa
    21121 aaattcccat tttttcgtta ctattattat aacacaaaaa ggtcagtcag aaaaatgtga
    21181 cctcttgagg aggctggctg attgagaata taaaggagga agactcatgg ctaaaggatt
    21241 cgctaaaggt cttgtaacag gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata
    21301 cgcatttaaa aagaaagtaa tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa
    21361 ccgtaaaaaa gcagctcgtc gccgcgtatc acgttaagaa acaaaagaag ttgggattat
    21421 tctcaacttc ttttttctat tcttttaaat agctaggtca aacttcaact gtggcttaac
    21481 agggtcataa tccaccaact caaaatcttc tgctttgata tcaaagaaat tagtcccatc
    21541 aggaacattt aaaaccaagc gtggttggca gtttgacggc tcccgacgga gcaattcctg
    21601 agcttgttca aattgattat catagatatg gaggttgttg atgaagtaga agaacttccc
    21661 aaccttccag ccaaaatgtt tggcaatcat catctgcaaa gccacatact gcatagcgtt
    21721 gatgtggtgg gccaccagca tatcattgga gcgctgggtc aaggtcgcat ccagatagat
    21781 ttccccatca acacgccgaa catcaaacat ggtctgaaag gcgcacggga gcagcccatc
    21841 tgtttcttcg aaagcttggt aatcccagag agaaataata ttgcggcggt tccaaggatt
    21901 ggtttccaac tgtttgagaa gcttattgat aatgtcgtgt ttcttaacaa cggcaccata
    21961 gcgctcacca atggttcccg tgtctccaac ttcccagtca ttccagtagt gaacattgta
    22021 cttgtcatta agcacttcta agctatttga ctggtcttgg taaatccaga gaacttcttt
    22081 gatggcggat ttgattgcaa tgggacgcaa ggttgtgata ggaaattctc ctttagataa
    22141 gtcgtactcg gaaaaggcac cagttacata cttggaatta gcaacagtcc catccttgta
    22201 cttaggacga gcctgctctg agaaaacacc ttcctttaga atgcgttcaa tattctcttt
    22261 aaaaatcgta tctgcttttg tcatttactc tcacctcatt cattgtccta actagtatag
    22321 cataaaaaat aaaagaggaa cattactaac tctaggttag cattttcctc tctcattatc
    22381 ttattgcaat acaagtgatg ctgctccgat aactccagcg tcatttccta gagttgcaag
    22441 agctaattta gtagatgtgc gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac
    22501 accttgtaga aggaattctc ccgcagctga cacaccacca ccgatgacga ttgttgatgg
    22561 gtttaggatt gaaccaatgt tagcacaagc gattcccaag taacgtgaga agttacggta
    22621 aacaatcaaa gcaaggtcgt ctccttcttt tgcgagatca aagacagtct tagcagttac
    22681 ttcttctccg ttatcaatca agcgtttcaa ggctgcatcg ccttcgtatt catcggcata
    22741 gcgacgagtc aagttgacaa ttcctgttgc tgaagcaact gtctcaaggc agcctttttt
    22801 accacaagta catgcaattg gttggtcaaa atcaacagtg atatgaccaa gttcacctgc
    22861 tgcaccagca acaccatgaa gcaatttgcc ttctgcgaca ataccaccac caacaccagt
    22921 accgagtgtc ataaagacaa catctggttg gttatcacca gcacccatcc agcgctcacc
    22981 aagagctgct acgttggcat cattatcgat gaaaaatgga atgcccaaag ctttttcaat
    23041 cttttgtttg attggttgaa gggttttcca gttcaagttg taggcaccga taacagtccc
    23101 tttttcacgg tcaacaacac ctggtgatcc cattccaata ccttggaagt ctgctgctgc
    23161 caatccaagc aagtccaaac gatgttgaat agactcaatc atatcatcaa cgatatgact
    23221 tccctcatcc aaaatgttgg tcttgattga ccattttcct tggatttctc ctgctgttgt
    23281 taagattgca aatttgatag aagttccacc aaggtcaatc ccaataatct tttgactcat
    23341 catattctcc tttttcattg tgtagtaatt gaaaatgctt acagtactag tatatcaaaa
    23401 tccattcact tatgcaaagg tttgcgtaaa tgaattataa ggaatttttt cgcctaccag
    23461 tatctgttaa tcatctaaat gatcaatggc atattgagct gcatcatttg aaaatttatc
    23521 aaaatcagaa gttaattgtc tatacatacg tttttttgac atgtggaata acgaattata
    23581 actttttgcc tttcctaaag cagcagaata ttcactattg ctatcattac tagaagaagc
    23641 tgtacttgct tgaccttcct tccaaactcc gtcagcgcca acataataac gtccaccatc
    23701 aacccattca ttgacagcca ttttaccatc cgattttaga tagtaatttc cttgccatgt
    23761 actgtaagca taagaaccat ctgatgtcaa ataataccaa gcttgatagg tggcatcata
    23821 aacccattca cctttagcca ttttaccatc tgatttcaaa tagtagtttc cttgccatgc
    23881 attgcgagca tatgaaccat ctgatttcaa gtaataccat gcttggtaag aagaatcata
    23941 aacccactca ccttgtgcca ttttaccgtt tgatttaagg taataagctc cttgccatgc
    24001 attttttgca taagaaccat ctgatttcaa ataataccaa gcttgataag aagagtcata
    24061 aatccattca ctctgtgcca ttttaccatc agctttcagg taatagcttc cctgccatgc
    24121 atttttcact agatttccat ttccatcaaa gtagtaccaa gcgccgtcct gcttaaccca
    24181 accacttgtt gttgctgaac ttgtgttgat ttgaatagcc gttgactgtt ttgctttaaa
    24241 agcaccctta ggagcatttt tcaattcgca agccacgcca tcatgatcgc ggtccaactt
    24301 ggcagaataa ccaggttctc cctcatgaag atccgaatag ccattagccc aagcttcctt
    24361 acaactcgaa aaatgaatgt tttcctctgc taacacaggt tgtgaaaaca aggctaaaat
    24421 tggcaacgtc accagactca tttttaaaaa tagacgttta ttcatttctt tctcccataa
    24481 ttatgacatc gatttcaata ttattttatc aaacttattt cagcaattca aggaaacttc
    24541 tggtcttttc tacaaactcc tttggttttg ccttattcaa gacatgaggg ccatctggga
    24601 taatctgaaa ttgggattct gatattagtt tatgaagact tctcatagaa ctaagattcg
    24661 gtttatcttt gataccacaa attagtaagg ttggataagg gcaagttcct gctatatccg
    24721 ttaaatcaag tgtcttcaac tcctcagaaa ctccgaccat aagagccttg tctgctccct
    24781 gtttttcaaa tactcttttg ggaagtagtt taaaaatcag caactgaaga taaaatagga
    24841 tattccctgc taatttaagc gggcatcctg acagaatcaa agctcgaaga tttggtaaat
    24901 cgtaactgga aagttctagt gccagggcag cacctaagga caatccaatc aaaacaaaag
    24961 gttctgtctc ttgagctagg tgctgataaa ctcgctcctt agcttgttga tagttactaa
    25021 ctccagaagg aaataactcg atagcctcag aaggataatc tgtcagtaga ttccgaactt
    25081 ctttccaaga ctctgctgac tgccctaacc catgcaaaaa tatcagtttc atctagttct
    25141 cctcaaggct tagttcatac aagcctctca ctgcattaca gccgtaaata gcttctgctt
    25201 gggctaaatc tgccaaggtc aagactttct cttctacctg tcctgtttct agcaaatact
    25261 gacggtaaat tcctggcaag attccaagtc ggataggcgg tgtgtagagt tttccagcga
    25321 ttttcagaac caaatttcct atagaggttt caagcagttc tcctgactta ttgtggtaaa
    25381 tcttctcttg ttctcctagg ctcaaatgcg gtcggtgagt ggttttaaag taggtaaagg
    25441 attgattcaa agcagcttcc tgaaggcaga cttgggcctg acaaaagctt gtactgagag
    25501 gggttaatac ttgacgattg acttctatct ctccagattt gctaaggctg attcgcaagc
    25561 ggtaatctcg attagcttca caatcctgac actcttcctc aatcttgtgt cccaagtctt
    25621 ctgcatcaaa aggaaaggca aaataacgac tagcttttct cagtctttcc agatgttgat
    25681 cttcaaacaa caggttcttc tggctgattt cccctgtcgt aatcagttgg aagcgagctt
    25741 gtttacgata aagaactgct gccttttgat gaacctctcg gtattcagat tcccatgtgc
    25801 tatcccaagt aatccctccg ccaactccat aaatggcttg acctttgtga agttgaatgg
    25861 tacgaatggc cacattaaaa atccgtcgtc catttggaag caagagacca atcgttccac
    25921 agtagactcc acgcggttga ggctccaagt ccttgataat ctccattgtc gcaattttcg
    25981 gtgcacccgt tatggaacca caaggaaaga gtgagcggaa gatttcaaca aggtccacat
    26041 cctctcgcaa ctgactcttg atggtcgaag tcatctgcca aacagttgaa tactgctcta
    26101 cctgacacag acgctccacg tgctcgctcc caacttcaga aatacggttc atatcattgc
    26161 gcaagaggtc cacaatcatc atattttcag agcgattttt gggatcctgt tccaaccaac
    26221 tggcctgttc aagatcttct tggtcagtta ccccacgctg agtcgtcccc ttcattggtc
    26281 gtgttgtcaa ctcgcgatca ttttgctcaa aaaagagctc tgggctcatg gaaatcactg
    26341 ccatctcgtc atgttccaca taggcattgt agcccgcctc ctgctctacc accatacgat
    26401 tgtagatggc aaaaggattg gcatttaact tttgcttaag ttggacggtg tagttgacct
    26461 gataggtatc tccctgccgt aaatgatggt gaatttgggc aatggccttt tcatagtctg
    26521 ctgcagacgt tacttcctgc caatttgagg gcaaatcaat atcctcataa gtcagaggaa
    26581 taggggaagt ttctacgcta tcatgaacag taaaataaag caggtactct cccagtaggg
    26641 gatccttgtg aactgctaat ttttcctcaa aagcaggtgc agcctcgtag ctgacatacc
    26701 ccaccacata ataaccttgc tcttggtagc tttccacttg tgccagcaaa tctgccactt
    26761 cttctacatt tctcgttttc aactctttaa taggcttggt aaaggtatat ctctccccca
    26821 aagtcctaaa atcaatcact gtttttctat gcatacctta agtatagcat aaaaaggcag
    26881 atacagacaa agctgatcta cctttttacg attttattca ttctatgctt gtggtgcagt
    26941 aaatagatca ccagagaaac cgtctgtgtt tttaaggaga gctttaaaga ctttcgattt
    27001 caagacaact gtatttcggt atttgtcttt aatactacta tcgtttagtt ccgttaaatc
    27061 tttagtaaca gcctcatcaa acatagtctt caactgttca taggttgaaa tttgagtgcc
    27121 attaatttca attggtgcaa aacctttttt agattttgta agaacttccc cataccattg
    27181 cttcttccaa tcttcaaggt ttgaaaattg gttattagaa actttcttaa taatgaaatc
    27241 atcacctaat agaccgttat tttctttatt ggctgcacct tgatgtttgc ttgaaacata
    27301 gtcaatgaac ccatgttcat atccatagta accccacata cggaaggcgt tatgtttgaa
    27361 ggatagagaa ccaggggcac cttgactcgt attaccgcca taaataccag ccatcatatt
    27421 aacattgaca tatgccgtac caaagtcctc tgggtggaag accttattac ctggatttcc
    27481 gtgaatggtc atgaaattat tatttaccaa gtcatcgatg gtttcaaggt tagttgtttt
    27541 ctcagcgtct atcaaatcac gcactttgtc ccattggtga ggaccactta gtttatttct
    27601 gtccattggt cgacgtgttt cgcgatcaat tttcttgaac cacttactat tgtcaccttt
    27661 aaccttagga agaacagcct cagcttctgc ataatcgagc atcatcatag cttcattgta
    27721 gttcttcatg taatggtcga tttggtcacg tgtttgaagt ttggtaggat ctggattata
    27781 ccattggttt ccatcatttg aacgttcaaa tgccatattt aatccaagtg cgccatattc
    27841 accttgatgt ccatgttctg ctggagtttg taacatacct tgagcaaatg cttcaagatc
    27901 tgtaccctgt cgatgtctat gacctcccag atatgccatt cggtcattta cgtgggtagt
    27961 ctcatgtgta aaggcagatg tgccatattc acttattaaa tccgacataa caaaatatac
    28021 agcatccata ggctgtggat cagcaaagat gtaagcatac gctccatacc catacttata
    28081 atcatgatac ttatcaatac gtccaaagaa ttcacgaata ggtgcataat ccggtttatc
    28141 ttttcgatga ccaaatctat caggccaacc accgggtgca ccatgattat cccatacagg
    28201 agttggaact acattttgac tcttaagaag tttatcgcgg acattatcag tggcaaggcg
    28261 tgaccaaaaa tctaagtaat taacttgctc tttagcacgt ttattgattt cactcttgaa
    28321 cgtttcacgt ttttcttctg tatctttacc atacttttca aacgaactaa atgagatagt
    28381 attatatgtt gaaatcataa ataaatgtgc atctttcaag ttcagaagcg ataaaatcat
    28441 gcgtccatgt tgtccgttat taagtccttc atatagacga tattttttat tagcaaatgc
    28501 agggttagtt gacggttgtt caactacata agcattattt tcaatagctt tcttaaacca
    28561 aacatttatg tctgtttcat ttgtgaatag tttcatattg taggtcaaga agtcatgtaa
    28621 gtttccagaa agagtatttt tcgccaccac ttcacggaag gactcctgtg tacgacttcc
    28681 cttaatatag tcctcttttg aaccaatttc tattaatcga tctaaaacac ttacattctt
    28741 accataaaaa tctggtttga atagcattaa ttctttaata ttgaagttat caaatttcac
    28801 accgtaataa cgatttaggt atgttaatcc taacaggaca gcagctttgt tatcttcaat
    28861 tttcttaatc aaggcacgtt ttgcagcttc atctgtattc agttgatgat cttcattttc
    28921 aactaatttt gtcacaaatg tattaagatg atcttttact tctttaaagc tttcttctaa
    28981 gtaaagattc ttaattgcat taactctgtt atccccagtt cttcctaatc gttgataaat
    29041 tggatcagat tgtaattcaa ttggacttaa aataccttca atagcactaa ttaaatctgc
    29101 acgatcttta acaaccatat ttggtgtata gacgacttca ccaagctctg cgacactgta
    29161 ttcttttact tgcttaactt gagagtcttt aggagaaatc gtaaagatat cttttgtctt
    29221 atctgcgtaa tgaaccataa tatggtcagc atctgtaagg tctgtaataa agtcattacc
    29281 tttcattgca gtcacagaca atacttcttt attcattaat ggactatcag ttgtaagttt
    29341 gttcccttga ttcacaatcc attctttgtt gtagaacggt tggagttttt caacattacg
    29401 ataaacaagc tcacgatttg cattataatc ttgaattgtt ttgtattctt catcacgtaa
    29461 tatacggcga ttcaacttat caaccaaatg ctcagttact tcaaatgtat cagcagtgat
    29521 acccatatcc ttaattttct tatcagcttc tacctgtgaa atttctttaa ttttagacga
    29581 ttgtttatgg gttttatctc cagaactcac accgataact gttgcattat taggtttaat
    29641 ccaattgctt acaaattcat catccatatc attagaacca aagaaaatat caccacgctt
    29701 aacattcact aagctgatat tgttatcaat ggttccccaa ggccagtctt taccaattaa
    29761 accgcctaca tcacctctag caacatcaat agtacctttg gctacagaat ttcttacatt
    29821 agaccaagca ccaacatctc ttggattaaa atcatgagct aaatgtccta ctatagcacc
    29881 tgcacgagta tttaaacctt taagttcaac atctgcataa gctttattta aattgcctcg
    29941 ataaatctca gatgcaatcc cagccaagtt ccacccttta tcaccaacag attgaacttt
    30001 tccgataaaa gcaacattag tcataatacc tgcatcatct aatttatcca aaatacccgc
    30061 aacattgtta ttaccaacga tagtacccgt tactttaata ttttcaacag ttgcattttt
    30121 cactgtttga gctaatgaag ctaattgatt tgcccaaggc atattaatat taacgttaat
    30181 taaattaata tttttgatag aacccccttc aactctatca aataatggac gagcagtgtt
    30241 atgaatggag aaatgcttac catcaacact tgttaagtga cctgtaaatt tacctgttac
    30301 atatgattta cttggtgtag gtacatttgt tgcatttaaa tccgatccta atttaaactc
    30361 accgttagga tttttctgca tagcatctac taaatctttg aagttatagt aaacgttatt
    30421 ttgcgatgct ttgggtttct ctatgtaata agtgtatgtt tgactcaaac tattatttga
    30481 atcacgttgg attaaatcag gagctgaagc agtaacttta aataaggatg tctcctcctc
    30541 agttacttcc tctatattag taatggcaag ccttgttact ttattatgat tagtggtaat
    30601 ttttagataa tatgacgtta gattttctgg aacagtttct agaaggctac tatctgtttc
    30661 atttccattc tcatccactt tcatcaatct tgtttcttta atatctttaa tctcaacttt
    30721 tttaaggtct aactgaactt ctttatcttc taatatttca gtttcttcac cgttacctcg
    30781 atcatagacc atggttgtgg atagtgtata accttgataa tatttcaagt tgtctaaagt
    30841 agcttgtaag ttattttctt ctaccgttac ttctttaaca actgttccag tattatcttt
    30901 tagagctact ttaatcgatt taatttctac tccagctggt ttagtcaatg tataactagc
    30961 tgtcgcactc ttcttcaaga catctttatc tgttttagcc cattccaagg ttggtttctc
    31021 taactctttt gtgccattct taataatttt gtcttgaggt ttttcaatca ctgtttctgt
    31081 gatagtagga gcgtcacttg ttttttctcc gcgaattgtt ttataggttt cagtaatttg
    31141 tttcttatcg tttacacctt cttgagttac ttgtcttgtt ccgcgtttta aagtgtcatc
    31201 ttcttgttct tttgtttcaa aaggaatgat ttcttctctt gtctcaaccg ttgtcccttc
    31261 aattggtttt gtaccacgga ttacctgttg atttacaggc tccttggtga cttccgtact
    31321 ggttgaaaga acttggtcag ttttaacccc tcctattgtt ttataggttg tttttgtaac
    31381 ttgacttcct ttttcaccat ttcgtaggac agtttcttcg tccgtgtact tggttgggtc
    31441 ctcagtcgtt tcagttttat agtcaagttc tgtagttgat tcttcaacga gtgttccttc
    31501 agtcacctta tactcaggta attgttctgg aacaagagcc tcacccacgt aatcttcttc
    31561 ttgcgtcccc ttagctgttt tagtctcctc ttttggttct acagtttctt cagccttggt
    31621 atctggagtt gactcttctt gtttcggtgt ttcctctaca gccttctctt cttcaggagc
    31681 ttctggttga ttttctggct cgactggtgc ctgttcgtct tttcttggcg cgactggttc
    31741 acctgcttgt tcaacttttg attcctcagc tggtttgtct gatggttgac tttctggctt
    31801 aactgctact ttttcctctg gttttgactc aacttctcca cctacttctt caactggagc
    31861 tggttctgct gaatcttctt tcccctcttc tactttagga agggtgtcgt cagtaggttt
    31921 tacctccgat tttggttctt cctttggact ttcttctgtt ttaggtgctt cttcttttgg
    31981 agcttcctct gtctctacta cttggttttc tgtcctagct tgctcctgat ttgttgttga
    32041 ttgaggagtc tcaacttcga ctacagtcac ctctccaggt tttgctgagg tttcttctaa
    32101 aacagtgtcc aagccaagcg ttttgaggat gtcacctgat agataaccaa catagcgata
    32161 gccctccatt tcaacaacac cctctcgact agccagtgct agggtcgcaa ctgggtctac
    32221 agcccctgca ctaggaagaa ctaccaatcc catagttcca actagaaaga cgctagcaat
    32281 tttctttctc ttgtagatta aaagcaagct cccaacagtc agcaaaccaa aagctgtcaa
    32341 aacagatgct tctgtccctg tttgaggcaa ctgatctttt tgatacacca aaccatatac
    32401 aacttcattc ctgtcaggct ttcctgtctg aattaaatct ttagcttctt gtgaaataat
    32461 ctctttattt acatagtgat aggtggctgc gtccactaca gaaggagcca tcaaaaggct
    32521 tccaagaaat acagagccta caactccctt aatcttacga attgaaaaac ggtctttttt
    32581 aaacactttt atctccttta ttcattctca aaacttccta atagcatctt gcggatagtg
    32641 cgcacgcgca cctccgatta attttggacg actagtcagt gccgttacat gggcatgacc
    32701 aatctctctc aaaatagggc gaatcggaac ctgaacatgc ttgacatgca tgccaattgc
    32761 agtgtctccg atatccaatc cagcatgagc cttgataaat tcaacctcaa ctggatcctg
    32821 cataaactta aaggctgcca actgccccga acctcctgca tgaagagtag gatggacact
    32881 gacaatttcc agaccaaact gctctgccac ctgacgttca acaacgagag cccgattgac
    32941 atgctcacaa ccttgaactg ctaaatggat acctctacta cctagaatac ccaagatagt
    33001 ctccactatc agctcaccaa tctcttgact ggattctttc ccaatctgac cacctagcac
    33061 ctcactagaa gatagaccta aaacaaaaag ggccccctgt ttcaaattgg tcttttctaa
    33121 aacatcttcc actacctgac gtgtttctct ttgaatctgt gtctcgttca tctctgttac
    33181 ctctgttgtc actcttctat cataccgttt tttcttgttt ttagcaagat agacaaccta
    33241 gaaagtttgc ccaattacgc ataaaactcc cagaattgac tgggagttag ctagtttcta
    33301 ttctatttat atatatttca actttcgttc ctttttgggg tctagaatca atcttcatct
    33361 ggtaattggc tccaaaatga agtttgagcc gttgatcgac attttgaaga ccaactcccc
    33421 cacgtttgag ttgactttga ctactatcac cagcatcttg gaagccaacg ccatcatcct
    33481 caatacggat gaccaatccc gaatcctgtt tctggacaga aagtttaata tggccctgac
    33541 cttccttttc cttaatgcca tggtaaagag cattttctac aaggggttgt aggaccagct
    33601 tgggtaagac taaattatca aaggcaacat tttcattaat ttcgtattcc agcttatctc
    33661 catagcgttg tttctggata aagagatact ggcggacatg attgatttcg tcagagagac
    33721 aaatcaagtc cttgccttga ttgagcgcca agcggaaata ggttgccaag gacttggtca
    33781 cctgcaccac tcgctgacta tcatgaaatt cagccatcca gatgatggtg tccaaagtgt
    33841 tatagaggaa atgtggatta atctggctcg aaagggcttg aagttggtac tgacgggtcg
    33901 tttcttcctg gctacgaata gctaccatca actgatcaat ctgattcaac atggcattaa
    33961 attggcgagt tacttctctc agttcatagg caccaacttc cttggcacga agattttgag
    34021 caccagaagc aatttccaac atggtttctc tcaaatcctt caaaggagca atccagcgtt
    34081 taagactgaa ccacactaag cagagacaga caagaagaga tgtgacactg gccccaagca
    34141 aggtccacaa gagctgactc cgaacctggt ctaacttttc caatgatgac acgccaagta
    34201 ccgtccaatc agttcctgca atcttctctt gactgacgta ggatttgtga ccaggagtat
    34261 aaccctgacc tgtatcgatg tagggtttca tagcctccat tttgctagac gaactataaa
    34321 ctgtgtgttg aggatggtag acaaattcat ggttttcatt gataatgaag gcaaagccct
    34381 gctgccccaa ctggagttga ttgagatagg cttccagagt ttcataagaa atatccaaac
    34441 gaagcacacc aagattggct ccctttgcat caacaagttc ttgagtgaca gaaatgaccc
    34501 actgactatc tgatttacga gctggagtca aaacaggcat agctccctga tgaatggcct
    34561 tttggtacca atcctcagcc atcatatcag aggaagtttt catctgcaca ctgtcatctg
    34621 tagaaatgac ctgaccagat ttggtcacca gcacaacagt tttcaagtcc ttatctgact
    34681 tcaagatggt caaaaacaaa tctcggattc cctcgacctt gtcttgactg ggattctcag
    34741 cataggccag aacatccgtc tgctgggtca aaccggtcga agtggtttct agttttttga
    34801 tataagactg aataaagtgg ctagtctggc tgatggtcgt ttggctgtta ccctcaatgg
    34861 tggcctcaat ggctgaagaa cttgattgat agtagaaagt tccaaccaga gctaggagaa
    34921 tgagaaagac cagaaagatg gaaataacca ttctaactaa aagagaagaa cgcttcatcg
    34981 gtcttctccc ttcttaaact gacgaggtgt cacacctgca atctgcttaa aacgttgggt
    35041 aaaatagttc atatcttcaa aaccaacctt ctctgcgatc tcataaatct tcagatctgt
    35101 agttaaaagc aagagcttgg cttgtttaac acgttctctc accagataat cctgaaaagg
    35161 caagcccaac tctttcttaa tcaaagaact cagataggtc ggactaaaac ctaagtcact
    35221 ggctaaagac tttaaactaa attggctatc agccagatga gactggattt tctgggccat
    35281 gtttccttca aacctattag tcaataaatc ttgtaactgc tcttctttct cttccttgtc
    35341 tagtttttgt ttgattttcc ccaacatttc ctcaatatcc tgacgagaaa agggtttgag
    35401 caggtagtcg tccacaccta gtttgacagc agacaaggca taatcaaaat catcgtaacc
    35461 tgttaaaaag accaaatgaa cctgaggata ggtttctcgt accaaactgg ccaactggat
    35521 gccatttaga tgaggcatgt tgatatcggt taaaatgata tctggaacct gcttttggat
    35581 caattcccaa gcctgccttc cattttcagc ctgaccgatg atttccatat cgtaggctgc
    35641 tacattgacc agtttagtca aaccttgtct taccagatat tcatcttcta cgattaagat
    35701 tgtgtaggtc atgctctgct cctttaccat ttactagtat cagtatagca aaattctcct
    35761 ctaactgctt aggaaagacc tcttatactc aataaaaatc aaaaagtaaa ctaggaagat
    35821 agccacaggt ttctcaaagt accgctttga ggttgtagat aaaactgacg aagtcagctc
    35881 aaagtatagc tttgaggttg tagataaaac tgacgaagtc agctcaaagt atagctttga
    35941 ggttgtagat aaaactgacg aagtcagtaa ccctacatac ggtaaggcga cgctgacgtg
    36001 gtttgaagag attttcgaag agtattaatc aacataatct agtaaataag cgtagccttt
    36061 ttcttccatt tggtctttgg gaataaagcg gatagagagg ctattgatac agtaacgtaa
    36121 gccgcccttg tcctgtggac catccgtaaa gacatgccca aggtgagaat ctcctactcg
    36181 gctccgcact tccatacgcg tcatattgta ggacttatct tccttgtagg tgacaacatc
    36241 tggactgatg ggttgggtaa aactaggcca gccacaacca gactcaaatt tgtcttttga
    36301 tgaaaagaga ggttccccag ttgctatatc cacatagata ccggattcaa atttatccca
    36361 gtaacggttt gagaaagctc gttctgtttg attttcctgg gtaactgcat actcctcagg
    36421 tgacagggtc tttttcaatt cctcatcact tggttttgga tatttgctgg catcaatgac
    36481 aggataggcc gcctgattaa cattgatatg gcagtagcca tttggatttt tcttgagata
    36541 gtcttgatgg taatcctcag ccaccacaaa attcttcaag ttttcctttt caactgctag
    36601 aggttgatcg tatttcttag ccacctcatc aaagacttgg ttaatcactt ccaaatcctt
    36661 gtcatctgtg taataaacac cagtacggta ctgggtcccc acatcatttc cttgtttatt
    36721 tttgctggtt ggattgataa tgcggaaata gtgaagcagg atttccttga gagaaatttg
    36781 cttggcatca taggtgacat ggacggtttc tgcatgacct gtttggttaa tcaattcgta
    36841 cttggttgtt tctcctctac catttgcata gcctgaaacg gcatccgtca ccccgggaac
    36901 gcgtgagaaa tattcctcca ctccccagaa acaacctcca gctagataaa tttcgtgcaa
    36961 gtctgcgtct ttactaattt ctgttttttt cactgttttt cctccttggc taactgccgc
    37021 cttttcaatt tgcgaggcat ctgtctgccc tgcatttcgt atcaataaaa catagaaacc
    37081 ggttatggct agaaaaaata ctcctagcaa caagaagatt tttaacttat cattcataag
    37141 acacctccta ggctaattcc ttcaaagttt gcaaaattgc atctttttcc atgaatcctg
    37201 gatgtgtttt gaccagcttg ccttctttgt ctataaaggc ttgggttggg taagaacgga
    37261 caccataagt ttccaaaagt ttgcctgatg ggtcaactag gactgggaga tttttataat
    37321 ccaatccctt ataccaattc ttaaagtccg cttcagattg ctccccctta tgtcctggtg
    37381 acactactgt caagaccaca tagtcatcac cagcttcttt agcaatctca tccgtatctg
    37441 gaagactagc cagacagatg gaacaccaag aagcccagaa tttgagatag actttcttgc
    37501 ccttgtaatc agataaacgg taggtcttgc catctactcc catcaattca aaatcagcca
    37561 cctctttccc tttagctgcg cttgttttac tagctgtctg ctccgtcttc atttcatctt
    37621 tcgtttggtg ttcactagtc acggacttgc ctgaacaagc cgtcaaacaa aggagcgaac
    37681 ccgctccaag aacacatgtt tgccattttt tcatattgat attcctttcc attttattca
    37741 aataattgac ttaaaattga agcatttcca aacagaacca agagtcccat cacaataatg
    37801 agaaaacctc ccactttttt gaggattccg agatagggat gaagttttcg gaaatgtttc
    37861 aaaacataac tagaggtcag agctagaagc aagaatggta gcgccaagcc cagcgtatac
    37921 accaacatga gaccagctcc ctgccaagct cctgaaccac ctgaagccgc caaggccaaa
    37981 acagacccca gaaccggccc cacgcaaggc gtccaagcaa aactaaaggt caagcccaat
    38041 aaaaatgcct gactatagcc cttaccattt tgcccctgtc cttgcagttg tagcctcttt
    38101 tccttataaa gccccttaaa gtgtagaatc tccatttggt gcaaaccaag aaggataata
    38161 attgccccag taagatattg gaaccaagaa gcataaagca aatcgcctaa aaaaccagct
    38221 ccatagccca acaaaataaa tataaaggaa attcctgcta taaaggccag agttcgtaat
    38281 aaactagtaa ctgagattga aaatttgccg ctagaagcct gagcaccatc cttatcatct
    38341 agtaacaccc ctgtatagac cggtaacaaa ggtaagatac aaggagaaaa gaaggataga
    38401 atccctgcca aaaagacact tagaaaaaag aaaatatgac ccataaagtt cctcctatca
    38461 ttttattgat agatttatta tactccttcc attttcgaaa aaacagggac aatgataggg
    38521 gaaaatagga atttaatcag atgatttaga aatcttggac aaaaactata caaaaaactg
    38581 tcaaagcaca aaagcgcata gtatcaaggt tctataaagt cttgatacta tgcgctttta
    38641 taatagataa atagttagtc ttttttaaag accggatctt tcaaactctg catactggca
    38701 ttgataaccg cgcctaggat aacaatttta gcaatcaaga taaaccaaaa catcataaca
    38761 acaagaagaa cggaacctaa aattcggaca tccaccaaat gatggacata gtaattgaga
    38821 taactagaga acagagttag taaacctaaa atcactaaga gaacaaaggc actgcctggt
    38881 agggtatagc taattttcct gttagataga ttgggaagaa aataataaag catgaccaag
    38941 atagcaaaga ggagggcgta aatcagagga cctgccaacc cttgtaaagc ctgatagata
    39001 atgccatctt ttgtccaata atgagcaagt aaagccaaaa tcatctgacc aaataagatc
    39061 aaaaacaagg caaacgcaaa gaggagctgc aagccaaaac tgactaggag actcagcatc
    39121 tgatgggaaa taagtccacg actcttttcg acgccataag ccttgttaaa agctttttgc
    39181 aagaaattca tagattttga aaaactccat aacgccgata aaacagaaaa actcaataaa
    39241 cctgttgaag gttgcgtcaa aacttctctg gctatttttt ccacaccttc atagaggctt
    39301 gggggcagaa cgtctttcat aaagcccaaa aattctccca caggaatctg aaaatagggg
    39361 aggatattga ccaccaccaa aagcaggggg aaaatcgaaa tcaaccaata gtaggctact
    39421 gcgacactgg tcaactcact atctgatgct tgataataat gcaaaaaagc ttttaataaa
    39481 ggtttgtcta tcagctcttt ccaccacttt ttcatgtcat atcatactcc ttcacttata
    39541 atcttatact caatgaaaat caaagagcaa actagaaagc tagccgcaag ctgctcaaaa
    39601 cactgttttg aggttgtaga taagactgac gaagtcagtc acatacatac ggtaaggcga
    39661 cgctgacgtg gtttgaagag attttcgaag agtattaact aatttcttct taccaattcc
    39721 accatatcat acggtagggt attggcagct tccttcaagg aatagttctc taagttattt
    39781 acattttgtc gtaatttctt ggcatactta gtcgtaatca atcgtttttc ttcgtattcg
    39841 aaaatcaact tgcgctccag ataatagcct ctcagcattt catcgatatt gttgggtttg
    39901 acacgattga taacccgttc gacaaaggca ccactgctga taatagctgt ttctcgaaga
    39961 cgagactcct gcataaaact aatcaaagag cgtctgtaga ctcccttcag gttttccaaa
    40021 ctttcaataa tcatctctgt attggcaaga tagagctctg caatttggtc ataatcaaga
    40081 gcacggagac ggctttgctc cttgttcttc cagctacgga aggtctttcc gagagtaaaa
    40141 acttcatgaa ggagaaaacg taaaatcctc aaggaaacaa gaaaataata ggtcagtctt
    40201 gaggcaagtt tacgattgat tccttgttct atatttttca gataacgttg gtaaactcgg
    40261 taagcacgat tgctaatgtt cccctcttca taggcctgtt ccaaaccatc actttcaata
    40321 ctaagaatca agagtttcaa agcagcccag tcttcttgat catcctggtt ttcttggctt
    40381 aaaatgagat tttcaatacg tccatgataa ttgtcaatag ccgcatagag gggaagttta
    40441 tttctagtgt cttccaactc tttttccaac tctagcgtta cttcattcaa aatggcgata
    40501 tgcatgagat aatccttgct ttcttcctct tcatcagaaa gatgaggcaa gaccaagaga
    40561 cctgttaaaa agctgacaag cgtcacacct gcaacaagga aaagcaagag aggatactcc
    40621 tgttctagat tacttggtat caagagaatc gtagcaatcg acaccgttcc cttaacacct
    40681 gaaaaggtca agagaaacat gtccttcata tacttattta gctttttctt gaggcgtcgg
    40741 gttctatagg cataatagcc atagatcata ataaaacgaa tgacaaagag gacaaaggta
    40801 agggcgatga gagatagcaa taaaagtaga ggattataga ttggattggt caagataggt
    40861 tctgctatca tttccaactc catccctaaa atcacaaaga cagaaccgtt gagcataaag
    40921 gtcactgtat gccagaccgt ctcggtcacc gtatccactt gggcttcgag gagcgtgatt
    40981 ttcttgaagc gacttgcctt taaaattcca gcaactacga cggcaataat ccctgaaaca
    41041 tggacttctt ctgccaggaa gaaggttacc aagggcaaac tcaattccag aaggagctca
    41101 ctagcaatat ccgttgctct cacacttagc aagaagctat ggaggaaacg attggtcatg
    41161 gctgttaaaa agccaattaa aaaaccgcct aggattgaaa agatgagcga actgctagct
    41221 tgccccagag aaaaagctcc agttgtccaa gctgtcaaag ctacctgaaa agccaccaaa
    41281 ccagaagcat cattcaagag tccttcgccc ttaagaatat tggacacgcg cttaggaaag
    41341 ctaaaacgct ccgaaagaga ggcaaaggcc accaagtccg taggaccaag ggctgcccca
    41401 acagccaagc aagctgccaa gggaaggctg aaccaaataa gatgggccaa gccacccaaa
    41461 ctcagggtcg agataaaaat cactggaaat atgagataaa caatgattcg ccagtgtttt
    41521 aaaatagccg taacatctgc ttcttcagcc tctcggaaaa gcaagggtcc gataaccagg
    41581 gccaaaaaca actccgtatt aagatgaaag tcagtattgg gtaaaaagag accaatcaca
    41641 attcccaaaa gaatctgcac caaagggaga ggcaaaaagg gtaggagctt attggttgta
    41701 cttgagacaa tcaaaaccag taaaaatagg atgaggtaaa tcagtaattc cacgcacgtc
    41761 ctccttaatc ttttttacaa caggattcaa atatctcctt ctgctctttg attttttggt
    41821 caatcttgga acagtctttg tgctcaattt ttctctggca ccgttccatt tcaagagcaa
    41881 ctaatttttt cttgatttta agcatttttt tgctcatatg cgcttggtct agcacgccca
    41941 ccgctcgttc gtggtgagtt gattcaacaa aattctggcg catggcatcc agcttttcgt
    42001 gtaggtattg tttatccatg tctgtatctc tctaattttt caatcatcac taaaaacggc
    42061 gggttgttga cttggtttaa agttcggtaa atggcagctg tgtactcttg ttggttcaac
    42121 tggatcacaa aatccaagac agcatctctc tcgaggtcgc ctccttcatg accatagtaa
    42181 atcataatag caattcgtcc acctttgaca agtaagccac atagcttttc taatgcctca
    42241 atcgttgtct gcggtcgggt gatgacagac ttatcagctg acggcaaata gcccagatta
    42301 aaaatccctg ccttagcttt tgtcacaaac tggtccagtg tctcatggcc ttgcaagatt
    42361 aactgggcat ttgtcaagcc agcctgatgc aaacgctctt gggtcttttc caaggcttgc
    42421 ttctgaatat caaaggcata gacttgcttg gctagcttgg ctaaaaaaag cgtgtcatga
    42481 ccatttccca tagtcgcatc cactacgaca tcctcttttg tcacgacctc agccaaaaaa
    42541 tcatgtgcca tctcaagtgg tcttttcatt ttcaaactcc tgttttacag ccttgcatcc
    42601 ttgaacactt ccacgacgtc gcatctccat ctcaatgctg ttgaggactt cccatttttt
    42661 gaggctccac ataggaccaa tcagcatatc cctaggcgca tctcctgtaa ttcgatggat
    42721 gacgatatgt ttgggaataa tttccagttg gtcacagatg accctgacat attcgtcctg
    42781 actcatcaat tgtaaacgtc cctcatggta atctcgttgc atacgagtat ttgtcataag
    42841 atggagcaaa tgcagtttaa tcccttgaat atcgttatcc gtgacacaac ggcggacatt
    42901 ttcaaccatc atctcatggg tttcaccagg caagccattg atcaaatggg aaacaatctc
    42961 aatcttggga tactttctca aacgcttgac cgtttccacc tacaattcat aagaatgcac
    43021 acggttaatc aggtcagagg ttgcttcata agtggtctgc aagcccaatt caaccgtcac
    43081 atgcatgcac tccgataact cagccaaata ttcgatggtt tcgtctggta aacagtctgg
    43141 gcgcgttcca atattgatac ctaccacacc tggctcattg atagcctgtt cataacgctc
    43201 tcgaataact tccacctttt catgggtgtt ggtaaaattt tgaaaataaa ccagatactt
    43261 ctgaacatcc ggccacttac ggtgcataaa gtcaatttcc ttataaaatt gctcacggat
    43321 aggcgcatct ggggctacaa tagcatctcc agaacctgaa accgtacaaa aagtacagcc
    43381 tccatgatcc acagttccat cacgattggg acagtcaaat cccgcatcaa tagggacttt
    43441 aaaagtcttt tctccaaaga attttcgata ataatcattc aaggtattat aagatttcat
    43501 gactttcatt ataacaaaaa tcacccacaa tctcaaaagc ctgactttcc tataaattcc
    43561 tctgtttctc gtttccatta gccttttttt atgatacaat atgggtatga ttttaatgaa
    43621 attagcatct attttattat tgatactgac cttagtcgtc tgcattatcc taaccaaact
    43681 ttttagatta aaaaaactag gacgaaactt tgcggatttg gcttttccgg tcttggtatt
    43741 tgaatattac ctgattacag ctaaaacctt tacccataat ttcctcccta gactggggct
    43801 agccctctcg atcctagcca ttattctcgt ctttttcttc cttttgaaaa aacgcagctt
    43861 ttactatcct aaattcatca aattcttctg gcgtgcagga ttcttattaa cccttatcat
    43921 gtatgtagaa atgattgttg aattgttctt aatgaaatag tcgaatccct aagcattttc
    43981 tagggatttt ttctttctct acaaaatagt atagacaata acactataca attttataca
    44041 aagaaaagag tctgggacaa tagtctctta tctccaaaaa aagcaacgga tttgccgttg
    44101 ctttttttgc atggttacga tagtcttggt aaaatagaat tgcccaataa accatttaga
    44161 aaggctattc catgcatatt cactataaca caaatcaaac aactttacca ctagaaatca
    44221 gttccttctt gccacaagac catctcgttt ttactattga aaaagtggtg aataccttgg
    44281 aggattgtca tttccacgcc ttctatcatg cctttgatcg cctgtcttat caccttaaaa
    44341 tgcttgtatc tactcttcta tttgcctatt cacaagggat tttctctggt cgaaaaattg
    44401 aaaaatggaa gagttagtga ccttagattg tttgtttatt gacggaacta agattgaagc
    44461 caatgccaac aagtatagtt ttgtgtggaa gaaaacgaca gagaaattct ccgccaaact
    44521 tcaagaacag atacaagtct attttcaaga agaaatcact cccctcctga ttaaatatgc
    44581 catgtttgat aagaaacaaa agagagggta taaagagtca gctaaaaact tagcgaattg
    44641 gcactataat gacaaggagg atagctacac acatcctgat ggctggtatt atcgttttca
    44701 ccataccaaa catcagaaaa cacagacaga ctttcaacag gaaatcaagg tttactacgc
    44761 cgacgaacct gaatcagccc ctcaaaaggg actatatatg aacgaacgct atcaaaactt
    44821 gaaagctaaa gaatgtcagg cgcttttatc tccccaaggt agacagattt tcgctcaacg
    44881 caagattgat gtggaacctg tctttgggca gataaaggct tctttgggtt acaagagatg
    44941 taatctgagg ggcaagtgag aattgacatg ggattggtac ttatggccaa taacctccta
    45001 aaatatagta aaatgaaata agaacaggac aaatcgataa ggacagtcaa atcgatttct
    45061 aacaatgttt tagaagtaga agtgtactat tctagtttca atccactata caataagaga
    45121 atgactcaaa attaaaaagc tagagttcca caattggaaa tatctagctt ttttgtggtt
    45181 gagaactatt ttgttccaga ctctttatct tctatttagg acaagagttt ttctttggtc
    45241 tttaatgata aagaaggtat caaaatttct agtcttcttt tttaccttta gtaactacta
    45301 atcctgcact caaacctaga agagctaaac ctgctgctac tgctgcttgg cttgacgcac
    45361 tacctgtatt tggtaactgg gctttattag tttgactagc ttcacttgaa tcaattggtt
    45421 ttgtatctgc tttttctgac acttgtggtt ttttagcttc ttgagctact ggtttggttc
    45481 caaccaagac gatgcggtct gtcggagctt ctaccacttc acggagtttt tcttccttac
    45541 ttccatcagg attaatcgct gtaaagatac gttctttacc agtttttcct tcttgttcta
    45601 cacgagtttc acctagatac agtgttgaat cttttttctc aactgtcttg taggccaaat
    45661 ctttttcaac aaattcgagt tttggaagat cttcttgtac agcagcaact gtcttctcag
    45721 aaactggttt ttccttagtc aagtggatac ggtattcctt gacttgtttt ccactttctg
    45781 aaacgaggcg aacaagtact ggaaggctat cttctccact atctaccaca gttgaagcta
    45841 cttgattgtt ttcttcaact gagacttttg gccgttgacc tttataggta atttgatagt
    45901 cttgacgatt ttcagcgaaa tcagcaagtt cttttccatc tacaagaatc ttcgattgcg
    45961 tactttcttg aggcaattca cttggtgcaa ggaaggtcat ctcaatcatc gcaacaccgc
    46021 tcttatctgc tttacgctcc atacgccatc tcatagcttt ggctttgaca gctttaaatg
    46081 ttacgttgat ttcatcacca gctgcgatgt ctttatccgc acgataaggc acagcttccc
    46141 aattttctgg attgttgaat ggatggtctg cgtcgtaggc ttggtagttt gaatagtagg
    46201 ttggcacttc aaactctgga ccgacatagc gttctaaaac gagtttagtt ggtgcatccg
    46261 taccactatc tgcaaagaag tgaagtttgg cttgcgcaac agtccgttct acaatcttac
    46321 cattttcacg gaagatcaca cccgctgata cttctggatt agaagatggt gttggagacc
    46381 agtttgtcca acgacgattt tctgaatgat ctccgtcatt gagatagtca acgcggtcat
    46441 gagagttttt gtcaatatca ttggttgctg aagcaaaggc ctggttactg ttttcatcat
    46501 agttagggtt atctgaaaga gcttcgccta gtttgtctgt cactcgtaca gtgacctcag
    46561 caacaagatc actaccaagg acatagcctc gaacggtaaa ttgacctgct tttgtcagat
    46621 tttctgctgg aacttcttcc cattcaactg acaaatcttt tgtttcgtag ccgtctttac
    46681 ctgtgaagta aactggaacc ttagtcggca attcaagtgc ttgacctact tgtagcaagc
    46741 gagcttgttt aaccgcagca actggtttat gagaaagtaa gttcttatcc ttagtgaagt
    46801 gcagacggta ttctcctaag atgtcgccat tttcagcttt cgcgatgaca cgaactggct
    46861 caccttcacg aacgcttgga acgacggtag cgagaccatt gttgctaaca cttgctgtga
    46921 ctgccggaac ttttccatct acagactcaa ggtagtagtc tgtcagatca gggttgaagt
    46981 ttgctaagtc tttaccgtca acttggattc ttgtttgtcc ttgcttggct gccgcaactt
    47041 gtttcgcaaa gatttgtacc tctgtgatag acgttcctag tttgttgtct gctctcacca
    47101 tgcgaatacg aacagcatag gtttcaactt tatcaaagct aaagtggttc atttctccag
    47161 ccttgagttg agcaggggct tttagattag taactggttt ccagttggca gaatcattaa
    47221 agacatggtc ctcattacca acaaaactag ggtttttagg agctgttggg acagtcttac
    47281 caacataata ctcaatcaca taagacttcg gtgcaccaac tccatggtct tcatggaagc
    47341 caacgcttaa gttatcaact gaacgtttgc tcaaaatacc tgaatctccg aataggacac
    47401 cgactgaagc ttctggatta gtacgattcc agtttgtcca acgattggct ggttggttat
    47461 tgtaggaaat gagcttgtca ttaacatttg aaactgggtc gcttggattt gagtctgaag
    47521 caaaggcaag tggcaagtct gaaccggtcc attggtcaga aatgtttgca ccttgctcag
    47581 tttgagcaga tacgcgaaca tgaagtttag ttgttaattg agtaccttct aagcgaccat
    47641 taactgtaaa gacaccttcc ttagcgtatt gctctggacg aatcgcatcc catgcaacct
    47701 tagctgatga aacgtgacca tttgaatcat atgtccgaac actttctggt aattgtggtg
    47761 cttctgcgat tggagttgtc acactgactt cttcaactga aacgatacct tctacagaga
    47821 cttttgcacg cgcttcaagg tcaattcctt caactttacc tagtacttca aatgtttgat
    47881 aggagtctag tttttctttc ggaatagctt gccaagtgac tttgtgagct ttagggaaac
    47941 ctttgtcata ctcaaccgtt actgttgttg gaagagtagg tttttgatgc aaatctgtga
    48001 ctacatttac aggacggata gattgcgcaa tcttcttctc agtattggct tggatagtga
    48061 gttcaacttg gcctttagct ccctcatatt cagcgttcag agtgactgct cctggcttat
    48121 gcaactcaag cattccttta cgaattgcga cttccccttc accacttgta gagaaggtta
    48181 ctttatcagc tggtaataca gcttgcgttc catcttgata gtgagctcga accgacaatt
    48241 tgacagtttg gtcttctttg agactgtcag ctttttccac ttgcaaactc aagtgagcaa
    48301 tttttggcgc ttcttcaagg aattgaattg cataggtttg aagagggcca ccatctttag
    48361 gctgaataaa gatgctcgca cgcatgccgt ttgctgcgct tgcttgaaga actgtcacat
    48421 cagcattttc agcacttgct gtgacttctg gcaattgggc accataagat agagtacgat
    48481 attgcattgg ttgtcgacta gtaagacctg ttactgcttc acctccaaca gtaacagttg
    48541 gcactacagg tgctgcagca tttccttctt ctaccacaag ggttgcatga atagtttctc
    48601 cagctaactg accagtcatt tgaatacgtg atccagctac tgaaagtttg gctttatcta
    48661 cttccgtaat ctcccagcta tctacttcgt actcttgtac acttccatca gtcaaaacat
    48721 aagaaacaga tttgtctaca gaattcaagt cagtatttgg agcaatacgt ttaactgttg
    48781 gtaattcttt cgcaattgct agaaccttga catgagcttc tacttctcgt ccgtcagcca
    48841 tacctttcac cgttacaata ccaggcttgc tcacatctac tgaagaccag gttacaggac
    48901 gttctgcacg gctaccatca ctgtatacaa acggaacagt ggtaggcatt tcaggtgcct
    48961 ctccaataat ggtctgtact tttggcactt ctgtccccaa aacagtcttc tcttgtcctt
    49021 ctttcttacc agtaaagaca gtgacttggt tcgatttcaa gagatcagag tgggcagtaa
    49081 gggtgaattt ccctgcttgt tcagttgatt tgacaatggc aacaccttta ccattaaatg
    49141 ctttacgaat ccaagaacca tctgcttgcg ccttatagcg ttcacggctg gcttgttctc
    49201 cgttatctac accgaccagt tgaccttggc catgcaattg gaagcgaacc agattattag
    49261 cagttggaac cacattcccc tggctgtcaa caatttcata gtagatgtaa gtcaagtctt
    49321 ttccatctgc tgcaatcgca tggtcttcct taataagacg aactgccgct ggcttaccag
    49381 cagtcgtaat cttatctcga gcaatttcct tgccagattc atcacgagca attgcttcca
    49441 aggtacctgg ttgataggca actttccatt caagataaag ttcattagca tttgcacctt
    49501 cttggtaagt ccgcccatcg ctggtttgtt ttttattgaa agtcttaaga ccaagagatt
    49561 ttccattcaa gaacaattct acactagaag cattcgaata agcacgaact ggaatcttac
    49621 cttctgagtc agctactttg gatgctaatt ctttgttttc ccagttccag tgaggaagaa
    49681 ggtgtaccat cggtttcttc ttaacagaaa cccattgact ttggtagaga tagaagtcat
    49741 gttttggaat gccggctgta tctacgatac caaagtaaga gctcttaaca ggagtttgat
    49801 tttggttgtg ccatggtgta ggttcaccaa tatagtccgt acctgtccag ataaactgtc
    49861 cagcatagcc agcgttgtca cggtcaaaag tccatgaagc ggttgctgtt ttcccccaac
    49921 caacacgatc atttccataa tctgactgtt cataattacg ctcaggtcca ttgctatgtt
    49981 tcaattcacg ttcagggcga tagtaacttc cacgtgtacg ggtagctgaa gatgtttctg
    50041 atccataaat caaccatttg ggatgcttag ctctaagggt tttgtaatta tcttcagaat
    50101 agttaaatcc aacagcatcg agttcatcag caattttctc atgccctccg ctaccattac
    50161 cgaaacggaa tttatctgct cccatggtaa catagcgagt cttatcaaca tccttgataa
    50221 ccttgaccaa acgtttaaca gttgctaaag agtgggcatc accattagct tcacctattt
    50281 cattaccaat tgaccacatg aagatagcag ggttgttttt gcctctttcg accatggtac
    50341 gtaggtcaaa atcagaccat ttttcacctt ttcgagcttc tgggtgagtg gcatcttttt
    50401 caaagaaacg tccatagtca taaggtttct tgccaccata ccaagtatca aaggcctctt
    50461 cctgaacgag taaacctagt tctgctgcga tttgcaaggt ttgctcacta gcagggttgt
    50521 gggttgtacg gatggagtta actcccatct ccttcatttg tttgagacgg cgatattctg
    50581 ctttatagtt ttcttctgct ccaagcgccc catggtcgtg gtgcaaggat actccatgga
    50641 atttaatacg ttcaccattc aaagagaaac cttcatttgg agtccagtga tagtaacggt
    50701 aaccaaacaa atccttctta gcatcaacca attgaccgtc acggtaaaca cgcgtaatca
    50761 attcgtacaa ggcaggtttg tcatttaaaa cggtccagag ttttggtctt tcaacttcta
    50821 aaatcgcatc taggcttgtt gattcatgtg cttttaaggt acgactcgct gtacgaacta
    50881 agcctgttac agcatgacca cctcgttcaa cgatttgata ttcggctaca agttcatggt
    50941 ctttgtcgtc cgtattgacg attttgctgg tcacatgagt ttcaaccttg ccatgttgtt
    51001 gttcttcaag ttttggtgtt aaaatagttg tcccattttt ctcaacatgc accttatctg
    51061 tcacttgtaa agtcacatca cgatagatac cacttcctga ataccaacgg ctacttggct
    51121 gtttgttgac tgcatggaca gcaatcacat tctcacgacc atctttgtga aggtatttgg
    51181 tgatatcgta tgagaactgg ttataaccat ttggataatg ccccactaac tgaccattga
    51241 cataaacttg agaatccatg tagacgccat caaaattaag gcgaacattt ttcttgaggt
    51301 ctttttcatc tagtttgaaa gtcttgcgat accaagcttc cccaccgttg agctgtccac
    51361 cttcattttg tgcaggagat tcatgatcga aatcgttaaa gatactccag tcatacggta
    51421 aatctaattt tttccacgta gatacgtctg catcaggttt aatggcttcc ttagaatttg
    51481 cattgagttt aaagtaccaa ttttgattaa aatccacttt cctgtcttca atcatttgat
    51541 tcacttcttc atttgttaca gctttagcat cttccttgag cggtttttct tgacttgaag
    51601 cttgtgattc tatccttgga gctttttctt ccggtttagc agacactttt tcctcttttt
    51661 gagttacggc ttcatcttct ttcttctcag atgcaatagc ctcagttgaa ctaggttcac
    51721 tttgttctgt cctttcaact acatttttag tttccaaagc tttatcagcc ttttcttcta
    51781 ctatcatttt ttcctcttta ggtttctcag cagtatgagt aataagtgtt tcatccgcat
    51841 aaactacaga ttctccagct atatttcctc ctaatagaac tgcacaagtc ccaatcatta
    51901 ctgagcaagc tcccacagca aacttacgaa tgctataaac tcttttccga ttccaatggc
    51961 ctttccccat aaaaccctcc ttatattata tttagtgcag ttagctactg ccaaagccca
    52021 agtggtatac atggtatgac aacctagttt caacaattta cactctgcga aaatccaatt
    52081 caaacttcgt cagtgtcgcc ttgccgtatg tatgattact gacttcgtca gtttcatcta
    52141 caacctcaaa accatgtttt gagctgactt cgtcagtctt atctacaacc tcaaaactgt
    52201 gttttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtttatat
    52261 tttataggag cgcattattt tgcttttgct gcgtactctt cgttacgttt gatcatttgt
    52321 tttctgtacc aagcaaagat accgatatag aatacaagga aggctactgc accaaggatt
    52381 gctttgatat caccagttgt agtgttacca attgtccaac caagaagttt ttcgattggt
    52441 ccttcaagag tagagtgagt aatcaattga gtttggctca caccttctgg gaaggcacct
    52501 acacctttag caagttctgt tgcaaatggt gcaataagtg tacctgaaag aaggaagagt
    52561 ggcaacaaga gtgttccgaa gataatcata cggagcaatt taccacgagt tacaaccaag
    52621 agagctggag taacacccat agcgatgata cctgcaagtg gcaagatacc atttccaact
    52681 tttgaaagaa gcactgcttc aatcaacatg attggtgcaa gtacgttggc acaagcccag
    52741 atttcagcac gaccagcgat gaatggccag tcaagaccga tattgaattt acgtccttga
    52801 agacgtttag tagcaacgtt tgtaatacct tgtgatagtg gttctacggc tgcgatgaac
    52861 catgaaccga taagtgagaa gagttccaaa gatacaccgg cagtcaaacc aagagacaac
    52921 catcctttga taacaagacg ccatttatct gcatctgcaa cacctgcaat tggatgtgga
    52981 gttcccataa taccgataac gataccaagg atgaaaccga tgaagaattt agatccccag
    53041 aaaccgattt tcttgttcaa tttagcagca tcaaagtcat atttatcaag gcctgggaag
    53101 aatttttcaa aaatcttatc caaaaccatg ataactgggt tcatcatgta gttcatgtga
    53161 gttgatgtca ttggtgatga acttggggcg ttaagaaggt catcaaatgt aggtttcatc
    53221 aagtcagagt tgataatttt caacacaccg acaaggacga tagctgctgt agcaataaag
    53281 agtgaaaccc cttgactcac accattgtta tcagcatacc atttaatcaa gagacctgtg
    53341 atagacaagt gccagatatc aaagatatcg acatcaagtg tatcggtttt cttcatagca
    53401 agcatcacta cgttgacaat caacatgatg agcaagaagt atagtgtcca agcagaaccc
    53461 caagtgattg ttgcgagtgg tgcccaacca acgtcggtaa tactcaattg gataccagtg
    53521 ttttcaacga attttgcaag tgatgctgag aaagcaccat ttagcatacc gatgatagca
    53581 ccgatacctg taagagcgat ggcaagtttg ataccacctt caagcgcttt ggagaatttc
    53641 actccaaaaa gtaaagccaa tactgtcaaa atgattaaca tgatgacagg tccacccatt
    53701 tctaagatgg gattgaaaac ctttccgatt aggtcaaaga ttgcatccat aacagttcct
    53761 ccctttttta tgttatatga atgttaacaa attagaatta gcttaatccg tgttctttaa
    53821 tagctgattc aatattgtca aatactggag cgctcattgc tggtatacgg aataagattg
    53881 gcccagcttc gataactggg atacctggtt caaaaccaag gtctgttgca gcgattggtg
    53941 taaagatatc gtaacctttc ataaggtctt cgtttacatc tttcaccatg actgcatcac
    54001 agtgaacatc ataaccacgg tttgaaagtt cttcttctag agcactttta atttggtgac
    54061 ttgagttaac acctgcaccg caggcagcaa gaattttaat catttggatt tcctccgatt
    54121 ttatttttta atagacaaga ttaagcggtt gcttcagcaa tgtaagcata aagtttttct
    54181 ggttcggaaa tttttgataa atcttcaaga tgtccatttc ctgtgaaaaa gtccatcaac
    54241 tgagccagaa tatttgtttg acttgaactt gaattgttaa taataaagaa gagtagggat
    54301 actt
//
LOCUS       DAVMCN010000009        49131 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVMCN010000009 DAVMCN010000000
VERSION     DAVMCN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49131
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.009"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(144..2033)
                     /locus_tag="VYP85_000660"
     CDS             complement(144..2033)
                     /locus_tag="VYP85_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1881207.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2171..3736
                     /locus_tag="VYP85_000661"
     CDS             2171..3736
                     /locus_tag="VYP85_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1881208.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3736..4500
                     /locus_tag="VYP85_000662"
     CDS             3736..4500
                     /locus_tag="VYP85_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1881209.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4699..4914)
                     /locus_tag="VYP85_000663"
     CDS             complement(4699..4914)
                     /locus_tag="VYP85_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881210.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5785..7035)
                     /gene="ilvA"
                     /locus_tag="VYP85_000664"
     CDS             complement(5785..7035)
                     /gene="ilvA"
                     /locus_tag="VYP85_000664"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1881211.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7085..7441)
                     /locus_tag="VYP85_000665"
     CDS             complement(7085..7441)
                     /locus_tag="VYP85_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1881212.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7679..7915)
                     /locus_tag="VYP85_000666"
     CDS             complement(7679..7915)
                     /locus_tag="VYP85_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881213.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8022..9044)
                     /gene="ilvC"
                     /locus_tag="VYP85_000667"
     CDS             complement(8022..9044)
                     /gene="ilvC"
                     /locus_tag="VYP85_000667"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1881214.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9110..9586)
                     /gene="ilvN"
                     /locus_tag="VYP85_000668"
     CDS             complement(9110..9586)
                     /gene="ilvN"
                     /locus_tag="VYP85_000668"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1881215.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9579..11279)
                     /locus_tag="VYP85_000669"
     CDS             complement(9579..11279)
                     /locus_tag="VYP85_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1881216.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11480..13147)
                     /locus_tag="VYP85_000670"
     CDS             complement(11480..13147)
                     /locus_tag="VYP85_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1881217.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13150..13515)
                     /locus_tag="VYP85_000671"
     CDS             complement(13150..13515)
                     /locus_tag="VYP85_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1881218.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13672..13860)
                     /locus_tag="VYP85_000672"
     CDS             complement(13672..13860)
                     /locus_tag="VYP85_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1881219.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13976..14152)
                     /locus_tag="VYP85_000673"
     CDS             complement(13976..14152)
                     /locus_tag="VYP85_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1881220.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14263..14460)
                     /locus_tag="VYP85_000674"
     CDS             complement(14263..14460)
                     /locus_tag="VYP85_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1881221.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14888..16432)
                     /locus_tag="VYP85_000675"
     CDS             complement(14888..16432)
                     /locus_tag="VYP85_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1881222.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16645..16947
                     /gene="gatC"
                     /locus_tag="VYP85_000676"
     CDS             16645..16947
                     /gene="gatC"
                     /locus_tag="VYP85_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1881223.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            16947..18413
                     /gene="gatA"
                     /locus_tag="VYP85_000677"
     CDS             16947..18413
                     /gene="gatA"
                     /locus_tag="VYP85_000677"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1881224.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAHVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TIQSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQVAAAFEATTDYHKQQPVIFGGDN"
     gene            18413..19855
                     /gene="gatB"
                     /locus_tag="VYP85_000678"
     CDS             18413..19855
                     /gene="gatB"
                     /locus_tag="VYP85_000678"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1881225.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LDGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19984..20544
                     /gene="efp"
                     /locus_tag="VYP85_000679"
     CDS             19984..20544
                     /gene="efp"
                     /locus_tag="VYP85_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1881226.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20566..20955
                     /locus_tag="VYP85_000680"
     CDS             20566..20955
                     /locus_tag="VYP85_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1881227.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20948..21370
                     /gene="nusB"
                     /locus_tag="VYP85_000681"
     CDS             20948..21370
                     /gene="nusB"
                     /locus_tag="VYP85_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1881228.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21420..21656)
                     /locus_tag="VYP85_000682"
     CDS             complement(21420..21656)
                     /locus_tag="VYP85_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1881229.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21669..22142)
                     /locus_tag="VYP85_000683"
     CDS             complement(21669..22142)
                     /locus_tag="VYP85_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881230.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(22160..22345)
                     /gene="briC"
                     /locus_tag="VYP85_000684"
     CDS             complement(22160..22345)
                     /gene="briC"
                     /locus_tag="VYP85_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1881231.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22507..23274)
                     /locus_tag="VYP85_000685"
     CDS             complement(22507..23274)
                     /locus_tag="VYP85_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1881232.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23271..24137)
                     /locus_tag="VYP85_000686"
     CDS             complement(23271..24137)
                     /locus_tag="VYP85_000686"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1881233.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24174..25541)
                     /gene="accC"
                     /locus_tag="VYP85_000687"
     CDS             complement(24174..25541)
                     /gene="accC"
                     /locus_tag="VYP85_000687"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1881234.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25553..25975)
                     /gene="fabZ"
                     /locus_tag="VYP85_000688"
     CDS             complement(25553..25975)
                     /gene="fabZ"
                     /locus_tag="VYP85_000688"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1881235.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(25972..26457)
                     /locus_tag="VYP85_000689"
     CDS             complement(25972..26457)
                     /locus_tag="VYP85_000689"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1881236.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26460..27695)
                     /gene="fabF"
                     /locus_tag="VYP85_000690"
     CDS             complement(26460..27695)
                     /gene="fabF"
                     /locus_tag="VYP85_000690"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1881237.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27717..28448)
                     /gene="fabG"
                     /locus_tag="VYP85_000691"
     CDS             complement(27717..28448)
                     /gene="fabG"
                     /locus_tag="VYP85_000691"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1881238.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28482..29402)
                     /gene="fabD"
                     /locus_tag="VYP85_000692"
     CDS             complement(28482..29402)
                     /gene="fabD"
                     /locus_tag="VYP85_000692"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1881239.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29395..30369)
                     /gene="fabK"
                     /locus_tag="VYP85_000693"
     CDS             complement(29395..30369)
                     /gene="fabK"
                     /locus_tag="VYP85_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1881240.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30488..30712)
                     /locus_tag="VYP85_000694"
     CDS             complement(30488..30712)
                     /locus_tag="VYP85_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1881241.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30772..31746)
                     /locus_tag="VYP85_000695"
     CDS             complement(30772..31746)
                     /locus_tag="VYP85_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1881242.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31746..32180)
                     /locus_tag="VYP85_000696"
     CDS             complement(31746..32180)
                     /locus_tag="VYP85_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1881243.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTINVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32274..33059)
                     /locus_tag="VYP85_000697"
     CDS             complement(32274..33059)
                     /locus_tag="VYP85_000697"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1881244.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33384..34748
                     /locus_tag="VYP85_000698"
     CDS             33384..34748
                     /locus_tag="VYP85_000698"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1881245.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34751..35122
                     /locus_tag="VYP85_000699"
     CDS             34751..35122
                     /locus_tag="VYP85_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1881246.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35336..36610
                     /gene="serS"
                     /locus_tag="VYP85_000700"
     CDS             35336..36610
                     /gene="serS"
                     /locus_tag="VYP85_000700"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1881247.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36635..37534)
                     /locus_tag="VYP85_000701"
     CDS             complement(36635..37534)
                     /locus_tag="VYP85_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1881248.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37644..38192)
                     /locus_tag="VYP85_000702"
     CDS             complement(37644..38192)
                     /locus_tag="VYP85_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1881249.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38410..39732)
                     /locus_tag="VYP85_000703"
     CDS             complement(38410..39732)
                     /locus_tag="VYP85_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1881250.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39823..39911)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40075..42411)
                     /locus_tag="VYP85_000704"
     CDS             complement(40075..42411)
                     /locus_tag="VYP85_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1881251.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42515..43063)
                     /locus_tag="VYP85_000705"
     CDS             complement(42515..43063)
                     /locus_tag="VYP85_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1881252.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43060..43362)
                     /gene="zapA"
                     /locus_tag="VYP85_000706"
     CDS             complement(43060..43362)
                     /gene="zapA"
                     /locus_tag="VYP85_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1881253.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43449..44321
                     /locus_tag="VYP85_000707"
     CDS             43449..44321
                     /locus_tag="VYP85_000707"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1881254.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            44333..44947
                     /gene="lepB"
                     /locus_tag="VYP85_000708"
     CDS             44333..44947
                     /gene="lepB"
                     /locus_tag="VYP85_000708"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1881255.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAHAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45027..45149
                     /locus_tag="VYP85_000709"
     CDS             45027..45149
                     /locus_tag="VYP85_000709"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV1881256.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            45226..47592
                     /locus_tag="VYP85_000710"
     CDS             45226..47592
                     /locus_tag="VYP85_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1881257.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYIFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILDAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47640..48923)
                     /locus_tag="VYP85_000711"
     CDS             complement(47640..48923)
                     /locus_tag="VYP85_000711"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1881258.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        14409 a        11240 c         9265 g        14217 t
ORIGIN      
        1 gctttttgcc gtgctctaaa atcatcgcca aatcatcaaa ttgaaataag aaatagttta
       61 gataaaacta ttgacttttc ttatagtttg tcttttttct atcttccatt atatcatact
      121 ttttcagtct atggtagctc tctttaaaag gcaccgatac tgccgccacc tccgcctcca
      181 gagaagccac caccagaact tccacttcca gaagatacag agtaggtgct tgctgtattt
      241 gcgacactag cataatggct catttgcgcg cttgaatgat aaaacagact gtgccagcca
      301 taagctacat agagattgat atctggattt tccacttgaa tctgatgaac cttcatcaaa
      361 tgactaacct tgtccgcata gccaaataag gtcgcataga ccaagaggcg attccagacc
      421 acaatacttt ccagttcagc ctgatccaat cgtgcaatct cacgcaacat attttcaaaa
      481 ctggtccaga gatagtagac ctcagctccc gcttcattta gaacaccatc acgattatct
      541 agtcgaagct tccaataata gaaaacagac aaaactaacc ctagaaaacc aagtattggc
      601 aaagggaggt aaagatagcc atgaacgtct aaactgtaca agaacaaacc aaatccgata
      661 aataggggca ggatagtcaa ggcacccata cccacttgca aggccttttc cccaccagtt
      721 aaaggacgat aataatctgg gagcccccag aaggaaactc gttttctcac tccttcttgc
      781 atctggttca atacctcttc aaaagaagat ttgagttgaa gccctcttgc ttgaatccgt
      841 ttttcatcag aaactttggc tctacgataa agactatcag ataccttgta atccgcaaac
      901 aaattggaaa gagtttcttc ttttttacct gaaaaagcta gatttaggca gtctttctca
      961 aagcttgaca aaccatcttc ttttactagc ctcaaaccaa ctgcatctcc ttctgaaatg
     1021 atagagacat tcccacggtc tatcacatct agcaaggtag cttgaataag ttgatcaaag
     1081 gtgaattttc cagctccctt gaccaaggga ctcacttcct ccaaggaggt cgagtagact
     1141 gcttctgata aaaccatagg ctctaattcc attggtggtt catagagacg atgatttttg
     1201 gcatatttga ctgaaggagt ggtctttctt ctataaataa aatagaagca gacactcaat
     1261 aacaaggaga tagaaaggat cgaagggagg acccaagtaa caagttgttt actctgatct
     1321 ttttctctaa caatcgagtc ttctatctta ttaaactctt ctaaacgatt ccctttcaat
     1381 ccctgatccc tagcgctagc aaaatcggtc cgaggccaat aggcatgcaa ctcaactcca
     1441 cgcttagccg gaagattgtc taaacggata gtataatcaa ggttactctt ttcaatcgtt
     1501 ccctctctaa aaagtttccc tgtatggaaa aagagttttt cagctccctt gtctcccctt
     1561 acatgaaatt caaacttttc aatagactct gaactatctg tcagaggttg ccaatttaat
     1621 tcagcgatat catcataaag gaaaagtaaa ttttttaagt tccagacgag gtcaacttca
     1681 actatgtcgc cctcctgacc tggattatag actctcacag tataaccatc cgcttcttct
     1741 gttacttcgc tagtcacatc tgctagttct gcaccgtttt tcgcggcctg aacctttgga
     1801 tgagggtcaa tgtcaaaccc gctaggcatc ttaccagcac gtccaagtcc cacgatttgt
     1861 cccttaaagt cctcctcaaa ctggtaaact atcttctgtc taaactctgc cgtattatct
     1921 gcatgaatat acaaatcccc ttgataagag tttatcttga aatcaatggc aaaaacagag
     1981 agtggaagaa ggcaaaacaa gcctaacacc agtaagaaaa aagttttttt catcaactaa
     2041 gccccctttt tatctttctt atcattatag cattttttcg taagtaaagg cttacttatg
     2101 ttgaaaaatt acgcattttt cgataaaata ggagacagtt attttttaat agatcagaat
     2161 aggagaaatc atgagaaaaa tatacttatc tattttcaca agtctcttgc tgatgctagg
     2221 acttgtcaat gttgctcaag ccgatgaata tttacgcatc gggatggaag cagcatatgc
     2281 tccctttaac tggacccagg atgatgatag caacggagct gtcaaaatcg atgggaccaa
     2341 tcagtatgcc aacggatacg atgttcaaat cgccaagaaa atcgctaagg acttaggtaa
     2401 aaaacctttg gttgttaaaa ccaagtggga aggtctagtc cctgccctta cttctggtaa
     2461 gattgacatg attatcgcag gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt
     2521 ttcgagcagt tactacacta gcgaaccagt tttgcttgtc aaaaaagatt ctgcctacgc
     2581 aagtgctaaa tctttggatg actttaacgg tgcaaaaatc acttctcaac aaggggtcta
     2641 cctctacgac ttgattgcac aaatcccagg tgctaaaaaa gaaacagcca tgggagactt
     2701 cgctcaaatg cgacaagctc ttgaggctgg tgtcattgat gcttatgttt ctgaacgtcc
     2761 agaagcactg actgctgaag ctgcgaactc taagttcaag atgattcaag tagaacctgg
     2821 tttcaaaact ggggaagaag atacagctat cgctatcggg cttcgtaaaa atgacaatcg
     2881 tattagccaa atcaatgcca gcattgaaac catttcaaaa gatgaccaag ttgccttgat
     2941 ggatcgtatg atcaaggaac aacctgccga agctacaaca actgaagaga ctagcagtag
     3001 tttctttagc caagtcgcta aaattctttc tgaaaactgg caacaactct tgcgtggtgc
     3061 tggtatcact cttttaatct ctatcgtcgg aaccatcata ggtctcatta ttggacttgc
     3121 cattggtgtc ttccgtactg ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa
     3181 actagtcggc tgggttctca atgtctacat tgaaattttc cgtggtacgc caatgattgt
     3241 tcaatcgatg gttatctact atggaactgc ccaagctttc ggtatcaacc ttgaccgtac
     3301 actagctgct atcttcatcg tttcaatcaa taccggtgcc tacatgactg aaattgtccg
     3361 tggtggtatc ctggcagttg acaagggaca atttgaagct gcgactgctc ttggtatgac
     3421 tcataaccaa accatgtgta agattgtcct acctcaggtt gtccgcaata tcctaccagc
     3481 aactggtaat gaatttgtca tcaatatcaa agatacatct gtattgaacg ttatctctgt
     3541 tgtcgaactt tatttctcag gaaataccgt ggcaacacaa acctatcaat acttccagac
     3601 atttacaatc atcgccgtga tttactttgt cctcaccttc accgtaacac gtatcctacg
     3661 ctttatcgag cgcagaatgg acatggatac ctacactaca ggtgctaacc aaatgcaaac
     3721 ggaggatttg aaataatgac acaagcaatc cttgaaatta aacacctcaa aaaatcctat
     3781 ggacaaaacg aagtgctaaa agacatttct ctcactgtcc acaagggaga agttatttct
     3841 atcatcggaa gctctggaag tgggaaatca accttcctac gctccattaa cctacttgaa
     3901 acgccaactg atggacaaat cctttatcat ggacaaaacg tcctcgaaaa aggctatgac
     3961 ctcacgcaat accgtgaaaa gttagggatg gttttccaat cctttaacct ctttgaaaat
     4021 ctcaacgttc ttgaaaacac aatcgtcgct cagacaactg tccttaaacg cgaacgcaca
     4081 gaagctgaag aaattgccaa agaaaacctg gaaaaggtcg gcatgggaga acgctactgg
     4141 caagcgagac ccaaacaact ctcaggtggt caaaaacaac gtgtggccat cgctcgtgcc
     4201 ctttcaatga atcctgacgc cattctcttt gatgaaccaa catcagctct cgatccagaa
     4261 atggttggag aggtcctcaa aatcatgcaa gatctggctc aggaaggctt gaccatgatt
     4321 gtcgtaaccc atgaaatgga atttgcccgt gatgtctctc accgtgttat ctttatggat
     4381 aagggtgtga ttgctgaaga aggtaaacca gaagacctct tcactaatcc taaagaagac
     4441 cgtacaaaag aatttcttca acgttatctc atactcaatg aaaatcaaag agcaaactag
     4501 gcagctagcc gcaggttgct caaaacactg ttttgaggtt gcagatagag ctgacgtggt
     4561 ttgaagagat tttcgaagag tatcaaataa aaagaaaagg ctgcatcaac cgtgcagtct
     4621 ttttgctgtc ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa
     4681 tccaccgtta tccaaagatt aatcttcaaa tttttcatga tttttttcat agaaatcaat
     4741 taagcctagg gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc
     4801 aatgatagac atttcacgcg cattcgtttc tttagagata cggtagcctg tgattttctt
     4861 atcacgaacc cagccaacaa ctgattctac tttttcaaag tttgacttag ccatgttttt
     4921 ctcctatttt cttctttata atatttaatt gtatacgttt ttactacttt tgtcaataaa
     4981 aaaaacatat attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc
     5041 gataatatat aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta
     5101 ttattaccct cttaaggtgc aaaattattc aagttcttaa aaaatgcttc tctatttccg
     5161 taagatagct tatttcttcg atttaagaac tgaagatgat agttctaacc tttagaaatc
     5221 caagccttct ctagctcaaa aactcctatc tttcttcctc aataaatcat ctgagagata
     5281 ggtattcctt atatccttca aattcatcac tcctttggat attgaggtgc tagcctagaa
     5341 gcagacaccc gattatctaa accatcctta atagagatga caagacagat aagctcagtt
     5401 aattacttat atatcttttt aatatggtat atttgtcaac aaaaagaaat caaatcatac
     5461 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaaatt gctcaaaaca
     5521 ctgttttgag gtttcagata gagctaacgt ggtttgaaga gattttcgaa gagtattaaa
     5581 gacagtatga ctatgcttgt caatagatag gaaatcaaaa tgaaggatgg aaatctgagc
     5641 caaacatcat aagtgctata atgaacagaa gtaagaattg cacgataagt tttctaaaac
     5701 cataggaatc gtcccctttc ttcatcttca ttatagcaca tatacatcag ttgtacaaat
     5761 aatatgatat ttttttatta gtcctcagac aagcatatta taaagcgttt cattaccatt
     5821 taagttaata taagctggat caaaaccttc cattctacgg atcaaacctg cataatcatg
     5881 cttatctgcc aaagcgatcc caatcaatac tgggcctgtt cccttgctag ctcgtttgat
     5941 atactcaaaa cgtgtgatat catcatttgg ccccaggata tcatttacaa actcacgcaa
     6001 agctcctgga cgctgtggga aattgaccac aaagtaatgt ttgataccat cataaatcaa
     6061 ggcacgctct tccatttctg gcatacggtt gatatcatta tttcctccag aaatgataca
     6121 acaaatggtt ttccccttaa tatattcagc taaaacctct aaagaggcga tactagccgc
     6181 tccagcaggt tctgcgacta tcccttgctt agagtaaagg tcaatcaagg tttcagaaat
     6241 caatccctca tcgacaccta ccaaagtttg aatatgttga cgagttgctt cataggtcaa
     6301 ctgacctacc ttttgcacag caatcccatc cgcaaattta tcaatttcct tgagtttgac
     6361 tggacctcca gcctcaaagg cagctttcat ggaacgcgct ccattcgcct ctactccgat
     6421 aacctcaatc tctggacttg tttccttgat ataggtagaa accccggcaa tgagaccgcc
     6481 accaccaaca ggaaccaaga cagcatcaaa atcaatcgat tcttttcgag cttcttctaa
     6541 aatctcataa gcaactgttc cttgacctgc ttgaacatga gcatcatcaa aaggatcaat
     6601 aaaggtacga ttttcagaga ctgtaaattc ttgagctgct ttggctgagg catcaaaggt
     6661 atctccaact agtttaatag ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt
     6721 ttgttgtggc gtagtaatag gcataaagat agtagcagga attttcattt cattacaagt
     6781 ataggctact ccctgcgcat gatttcccgc agaagcgcag actaccccac gttcacgttc
     6841 ttccttgctg agctgggaaa tggcataata ggcaccacga attttaaagg agcgaacacg
     6901 ctgggcattt tcttttttca aataaatctt agcaccatac ttctccgata aataatgatc
     6961 gtaatccagt ggagtattca caaccacacc gttcaagacc ttgtgagcct tgattatatc
     7021 ttttgaactt aacatataaa acctcttttt ctataaaaaa cagtcactaa tgactgtttt
     7081 ttagttattc atctccgaaa acttcagtaa cactttcatg gtatttatga gccatacgaa
     7141 tcgaaaactc tttaggaagt tcataacgat ttgtggaaat ccaatcatat aaccattcta
     7201 ccaaactttc ttcactatca ttacgatgga agataaaata gtttaaaatt tctttatatt
     7261 ctacatcatt caaatccaac gtgtctacaa attgactacg aggaacaaaa ttagaatcta
     7321 attttcttag ttgatctgtc aattctccca attgtaaatc caactgaaaa aatagttttt
     7381 gcagttgcct atcagtttca tcacatcctg tcttgataga aaacaaattg gtaatattca
     7441 tatgatttca acccctaaat aagtacatct aatatcccac gaatagctga agctaaagtt
     7501 ttcgcagtcc agtcatttaa acccgattct ttcaatccag atgcaataat ttgctctatt
     7561 tgatataaac cgccatctat cgtctcattt attctgcgaa gaggaccttc aatataggat
     7621 aaagcttctc cgaatctaac agctgattta ggtcctaatg atttaccaac tatatttgtt
     7681 aatgtttttt atttctcaaa atccatttcg ctatataacg agcagattta gtcgcaccag
     7741 ctctctcaaa cggagaatga atttcaagac cttcttctct agctatttgt gccaatttga
     7801 agaattgttc aaaggtcata tgcaacctac catcttcaaa attagcatca tcataaatgt
     7861 taattacagc attttcatca tacgaccaat ctgctttatt ttggtctgct agcactatta
     7921 ccgacggtgt aattacatta tacaactaga accaataata acgatgcaat ttttctcata
     7981 atctttttca taaaatcatc tccagcgcta tatatttcta attagttata gattttgaat
     8041 gcatcatcgt cgtttttacc aacaaatggc attgctttac gcaattctgc accaactttt
     8101 tcaatttcaa ggttagctgc ttgttcacgg taagcagtca attttggacg tccagcttta
     8161 tagtcattta caaagtcatt tgcaaattta ccattttgga tgtctgccaa gacagccttc
     8221 atattttctt taacttgttc agtgattaca cgtggacctg atacatagtc accgtattca
     8281 gcagtgtttg aaatagattg acgcattttc ttgaatccac cttcgtagat caagtcaacg
     8341 atcaatttca tttcgtgaag aacttcaaag taagccaatt ctggagcgta acctgcttct
     8401 gtcaagactt cgaaacctgc ttcgataagg gcagtcaaac caccacaaag tacagcttgt
     8461 tcaccaaaca aatcttcttc agtttcttct ttgtaagttg tttcaagaag acctacacga
     8521 gccgctccaa cacctttaca ccagtccata gcaatgtttt tagcatttcc tgttgcatct
     8581 tggtatactg cataaagagc tggaacacca aatccttctt cgtaagtacg acgtaccaag
     8641 tgtcccggtc ctttaggagc acacatgaag acatctacat ccgcaggaac tttgataaat
     8701 tcaaagtgga tgttgaaacc atgggcaaat ccaactgcgt ttccagcttc caagtttgga
     8761 gcgatttctg cttcgtacaa ttcttgttga atttcgtctg gcgccaagat catgataaca
     8821 tcagccaact tagtagcttc tactactgtg taagtatcaa atccatcttc ttttgcttta
     8881 tcaaaagatt tacctggacg tacaccgata ataacgtcac gacctgaatc acgcaagttt
     8941 tgagcatgcg catgtccttg tgaaccataa ccgataacgg cgattttttt accgtcaagt
     9001 gctgctactt taacatcttt ttcatattcc atttgaactg tcatagcttt tctctctttt
     9061 ctattattta ttgcctttta ggctggttta ataaatttaa gttggatttt taatcgcggg
     9121 taaatccagt tgcacccgtt cgagcaatat tgcgaatacc gtatgggcga atgactcgca
     9181 atagggcttc gctcttttct gcatttcccg tcatctgaat ggtaatcgag cttggcgcta
     9241 cgtctaccac tgttgcacgg aaaggttgaa taatcgctaa aatctcagct ctcttctcag
     9301 ctggcgctga catcttaacc aaaatcacct cgcgctccaa atgaggcttg tctgtaatat
     9361 ctcgaatgcg aatcacatca atctgacgat tgagctgttt gatgatttgc tccacttcat
     9421 catgagaagc aacatcaata ataatagtga tacgcgatac attcggatct tctgttgctc
     9481 caacagagat gctttcaata ttaacctgac gacgagatag gacacctgta aagcgattga
     9541 ggactcctga acgattttgt agttttgctg ttaacattct acgcatggaa ctgcaccccc
     9601 aacatctcat gattactctt accagccggt accattggta acacctgttc cttacgagaa
     9661 atatctacct caattagcat aggaacatcc tcagtgatga cttcaaggtc ttgagccaag
     9721 gtctcaggat tgtcaaactt atagttttta ataccataag cctgcgccat caattggaaa
     9781 tcaggaaggg tatcaaagac cgactctgat gttctgcctt catagaagga ttcctgccac
     9841 tggcgaacca ttccaagtga atgattgttc agcataacca ccttgattgg caccttgtaa
     9901 atattcaaaa tagccaactc ctggttggtc atttggaaac caccatcccc aacaaacaag
     9961 actacttcct tatctgggtt agcaatttta gcaccgattg ctgctggaat tccaaagccc
    10021 attgttccca aaccacctga agtcactaac tgacgctcat tttggtaggg ataatactga
    10081 gctgtccaca tttggtgttg accaacgtct gttaccacaa tggcatctcc attcgtcaat
    10141 tcaccaattc gttcaataac tgcttgcggt tgaaccacac gctctttctt gtcataagaa
    10201 cgaacacgat tcttgtcttt agtgactttc tcaatccact tttcagtatt gttgtgaact
    10261 gttggttctg ctagcaacat ttgcaaggcc ttcttagcat ctccaactac aggaatgtct
    10321 gcactgataa tcttgccaat ctcagctggg tcaatatcaa tgtgggcaac cttagcattc
    10381 ttagcgaaag tcttaggatt ccccgtcaaa cggtcatcga aacgagaacc aatactaatc
    10441 ataaagtccg cttccgtcat ggcaatattt gctgcgaatg acccgtgcat gcctcccatt
    10501 ccaagaaaga gtgggtgact cgttgcaatc gttccttgtc ccaaaagact ggttaccact
    10561 ggaatttgat agcgttctgc aaattcattt agttccgtag cagcctcagc ataactaatt
    10621 ccaccaccag ctaacaagac tggcttttta gccttggaca attgcttcaa gattttcttg
    10681 atttgcatat cattcggctc aagagtcggc tgataacttg gtaaattcac ttctggtgaa
    10741 taaatgaagt ctgtttctaa agcagatatg tcttttggta ggtcaattac aactggccct
    10801 ggacggcctg tagttgcgat atggacagct tccgtaatga tacgcggaat atcagctgtc
    10861 tcacgaactt ggtaattgta cttagtgatt ggcatggtaa ttcctacgat gtctgcctcc
    10921 tgaaaggcat ccttcccaat ccctgctcgc gccacctgac ctgtaaagac caaaagggga
    10981 acgctatcgc tcatagcatc cgcaatccct gtaatggcat ttgttgctcc tggtccacta
    11041 gtgacgacgg caacacccaa ctttccagtt gatttggcat aaccttcagc ttcatgcaaa
    11101 caaccttgct catggcgccc tagaatgtgg cgaatgcctt taaaattata tatcgcatca
    11161 taaaaaggca aaaccgcacc accaggataa ccaaagatgg tatcaactcc taaatcacga
    11221 agtgtttcca aaactaggtc cgaccccgtc ttaggagatt ctaaactgat tttctccatt
    11281 gttccccttt ctttcctctt aaaaataact tgttactatc ataccatttt ttcaaaattt
    11341 ttcaagataa aagaagaaat tttctgaatt ttctatttta acgtttattt atgaatgtta
    11401 tttttgtttt tattaaaaag ataccgattt catttactaa aaaagaaaaa agaactgatt
    11461 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    11521 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    11581 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctatcttcat
    11641 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    11701 tttttccatc caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg
    11761 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    11821 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    11881 gaggaagagt gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt
    11941 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct
    12001 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    12061 cataatccac gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa
    12121 tcaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    12181 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    12241 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    12301 catcgttaac aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt
    12361 agtcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    12421 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    12481 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    12541 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    12601 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    12661 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    12721 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    12781 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    12841 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    12901 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    12961 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    13021 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    13081 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    13141 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    13201 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    13261 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    13321 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    13381 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    13441 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    13501 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    13561 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    13621 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    13681 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    13741 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    13801 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    13861 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    13921 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    13981 tcaggtcttg cgtgacattt tctgctctcc acatgccatc gttgattaac agaacaccag
    14041 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    14101 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    14161 cacgagactc gcttacatac tttggaataa aatacctaaa aaagccgcat atgaaagtcc
    14221 ctcaaagggg agacgataac ctttcagaat actactgtca atctaaacat tcacaatctc
    14281 actattcaaa gtctctagtc ttttttccat taattggaac cattctcgcg gaaggtcatc
    14341 attaaaaaca taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc
    14401 aactttatcc atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac
    14461 tttttatctc atttcttttt attcccatca tatgtttcta cgtaaccatt attttcgcct
    14521 attcgttcgt aaaaccatac cagtggagat tttagatgaa gtcccattac ggtttacaat
    14581 ttttacatta cgacacagag ttttacaaat cgatttcatt tgccaaacgt agttagtaag
    14641 gcagttagct aggctaccta ctttctgcta cgacggaaaa atccacaaat caataccatt
    14701 cgtggatttt tcctagtgaa gcgtttaggt aagccgccat agcggttacc gattattaga
    14761 ttacgacacg gagtttggca aatcgattct atttgccaaa cgtagttagt gaggcagtta
    14821 gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc caattgttgg
    14881 tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca aaccagcgga
    14941 gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg gctaagatat
    15001 tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga acggtctttt
    15061 tacccattgg gctcatgacc acttccgcat tgtattcgcc ttccatacgg tgtttaaaga
    15121 cttcaaactg gagttgacca acagctccca gcatgtactc acctgtttgg taattcttat
    15181 aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag gatttttgct
    15241 tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt ggcaatggtt
    15301 caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa gtaccggtat
    15361 cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga ctctccgcca
    15421 taaactgggt aacattagat agtttagccc ccttaccagt acgagggaga ttgacactca
    15481 tgccgcgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca cggtgacgag
    15541 gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca taaggatcca
    15601 caatttcacc atctgttttc ttgtgaccat gtggttctgg agcaaacttg aggaagattt
    15661 caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt
    15721 ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa agctcaatgt
    15781 catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca tcttctaggc
    15841 tagcaaaacg ctcatcccct ttataaagtt ctaaacgttg gttatagagg tcatacaagc
    15901 cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca atgcccaaga
    15961 tttcttccaa ttcttgcaag agttccaaag gctcacgacc gtcacggtcc agcttgttca
    16021 taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc ttggtttgag
    16081 cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc atcaaggtac
    16141 gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc
    16201 cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc ttctcgatat
    16261 ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta ccagcctcac
    16321 gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc gcgtccgggt
    16381 gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc ataagttctc
    16441 tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta cattggattt
    16501 taccattcct ttcaatactc cattatatcg gattttagca tttttttcaa tttctatttc
    16561 ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca gactaaaaat
    16621 catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac acacgttgcc
    16681 aatctttcaa aattaagatt ctctgaagaa gaaactgctg cctttgcgac caccttgtct
    16741 aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt cgcacctact
    16801 acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga aggaatagac
    16861 cgtgatcgct tgtttaaaaa cgtacctgaa aaagacaact actatatcaa ggtgccagct
    16921 atcctagaca atggaggaga tgcctaatga cttttaacaa taaaactatt gaagagttgc
    16981 acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca acacttgaaa
    17041 atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag gagcaagctc
    17101 ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc ctttcaggaa
    17161 ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact gctgcctcaa
    17221 aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat gcaaaaacca
    17281 agggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt ggttcaggtg
    17341 aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt cctggtgggt
    17401 catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca cttggttctg
    17461 atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa
    17521 cctacggaac agtttcacgt ttcggtctca ttgcctttgg cagctcatta gaccagattg
    17581 gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt gccagcgaag
    17641 atgctaaaga ctctacttct gctcatgtcc gcatcgccga ctttacttca aaaatcggcc
    17701 aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa ggaattaacc
    17761 cagaggttaa ggaaaccatt caaagtgccg ctaaacactt tgaaaaactt ggtgctattg
    17821 tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac atcatcgctt
    17881 catcagaagc ttcatcaaac ttgcaacgct ttgacggtat ccgttacggc tatcgcgcag
    17941 aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggc tttggtgaag
    18001 aggtaaaacg tcgtatcatg ctgggtactt tcagtctttc atcaggttac tatgatgcct
    18061 actacaaaaa ggctggtcaa gtccgtaccc tcatcattca agatttcgaa aaagtcttcg
    18121 cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac ttggactcac
    18181 tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct gtaaacttgg
    18241 caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct gtcggactcc
    18301 aattgattgg tcccaagtac tctgaggaaa ccatttacca agttgctgct gcttttgaag
    18361 caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac taatgaactt
    18421 tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa aaatcttctc
    18481 acctacttct gcccacttcg gaaatgatca aaatgccaac actaacgtga ttgactggtc
    18541 tttcccagga gttctgccag ttctcaataa aggggttgtc gatgccggaa tcaaggctgc
    18601 tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga actacttcta
    18661 tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg gatataatgg
    18721 ctggattgaa gtcgaactag aagacggtac gaccaagaaa atcggtatcg aacgtgccca
    18781 cctagaggaa gacgctggta aaaacaccca tggtacagac ggctactctt atgttgacct
    18841 caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc gttctcctga
    18901 agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg gcatttctga
    18961 cgttaagatg gaagaaggtt ctatgcgtgt ggatgccaac atctcccttc gcccttatgg
    19021 tcaagaaaaa ttcggtacca agactgaatt gaagaacctc aactccttct caaacgttcg
    19081 taaaggtctt gaatacgaag tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat
    19141 ccgccaagaa acacgccgtt acgatgaagc gaataaagca accattctca tgcgtgtcaa
    19201 ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct ttgaaatttc
    19261 tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag aacgtcgtgc
    19321 gcgttatgta tctgaccttg gtttatcaga ctacgatgct agtcagttga ctgctaataa
    19381 agtcacttct gatttctttg aaaaagctgt tgccctagat ggtgatgcca aacaagtctc
    19441 taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca
    19501 aatcgaattg acaccagaaa acttggttga aatgattgcc atcatcgaag acggtactat
    19561 ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg
    19621 tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct tgatcccaat
    19681 catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt caggcaaacg
    19741 taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc aagccaaccc
    19801 acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa actagacaga
    19861 acaaaaccag ccctaaggtt ggttttttct tctctaccaa ctcccaataa ctattttggc
    19921 tttatttcca gagtatttta tggtaaaatg aagagtaata atatttatta aagaggtaaa
    19981 aacatgattg aagcaagtaa attaaaagct ggtatgacct ttgaaacagc tgacggcaaa
    20041 ttgattcgcg ttttggaagc tagtcaccac aaaccaggta aaggaaacac gatcatgcgt
    20101 atgaaattgc gtgatgtccg tactggttct acatttgaca caagctaccg tccagaggaa
    20161 aaatttgaac aagctattat cgagactgtc ccagctcaat acttgtacaa aatggatgac
    20221 acagcatact tcatgaatac agaaacttac gaccaatacg aaatccctgt agtcaatgtt
    20281 gaaaacgaat tgctttacat ccttgaaaac tctgatgtga aaatccaatt ctacggaact
    20341 gaagtgatcg gtgtcaccgt tcctactact gttgagttga cagttgctga aactcaacca
    20401 tctatcaaag gtgctactgt tacaggttct ggtaaaccag caacgatgga aactggactt
    20461 gtcgtaaacg ttccagactt catcgaagca ggacaaaaac tcgttatcaa cactgcagaa
    20521 ggaacttacg tttctcgtgc ctaatctcta gaaagaggtc attctatggg aattgaagaa
    20581 caacttggcg aaatcgttat cgccccacgt gtacttgaaa aaatcattgc tatcgctact
    20641 gcaaaggtag agggtgttca ctctttttca aacagatcag tgtctgatac cctttcaaaa
    20701 ctttcactcg gccgtggcat ttatcttaaa aacgtggacg aagaactcac agcagatatc
    20761 tatctctacc ttgagtacgg agtaaaagtt cctaaggtag cggttgctat ccagaaagct
    20821 gtcaaagatg ccgtccgtaa tatggctgat gtagaactcg ctgctatcaa tattcacgtt
    20881 gcaggtatcg tcccagataa aacaccaaaa ccagaattga aagatctatt tgacgaggac
    20941 ttcctcaatg actagtccac tattagaatc tagacgccaa ctccgtaaat gcgcttttca
    21001 agctctcatg agccttgagt tcggtacgga tgtcgaaact gcttgtcgtt tcgcctatac
    21061 tcatgatcgt gaagatacgg atgtacaact tccagccttt ttgatagacc tcgtttctgg
    21121 tgttcaagct aaaaaggaag aactagataa gcaaatcact cagcatttaa aagcaggttg
    21181 gaccattgaa cgcttaacgc tcgtggagag aaacctcctt cgcttgggag tctttgaaat
    21241 cacttcattt gacactcctc agctggttgc tgttaatgaa gctatcgagc ttgcaaagga
    21301 cttctccgat caaaaatctg cccgttttat caatggactg ctcagccagt ttgtaacaga
    21361 agaacaataa aaagaaaaag tgtttgatag atatcaaaca cttttttctt tgcctcccac
    21421 tatctaaaaa aatgataata gatataattg taaacaaaaa tccagatagg ttttgcatga
    21481 ttgagaaagt taaaaaaact atggcagaga atcgttaatc tcagattgtc ggtagaacga
    21541 taaacaaggg caaaaaagaa accaatcaga ctataatata ataaactaat tggatctctg
    21601 tgagatagta tcaaatggct aatcccaaag atgatagcag ataggataac atccaaatag
    21661 tacttggact agggaaagaa ggtattcata aaataccctc tatcaagagt ctcctcaaaa
    21721 acaggaccga tgattacagg caggacaaaa gataagatag tcgataaaaa ggttggttgt
    21781 ccatttgaaa aaagcacggt aaaatactca tcatgaatat tcctatgatt aatcaaatga
    21841 gcatagcgtg cccaaaaatt accgagaatc tgataaacca cataagttgc aaataagtag
    21901 aagacaaatg accagttcca gctctttttc tcaaagataa agagcatctt tttctttttt
    21961 aacctccaaa ttaatagaag gaaacttccc actaatccca ttgttaaaat aagagaatag
    22021 acatcagctc ctaaccctaa aatgatcgtc acatacaatc caattgtttg tggtaaatag
    22081 gtagatagta aaataataag caaaaatatt ccaaattgtc ttagtttttt tgtgtttctc
    22141 atcgtacttt tttgaaagat taccctgctc ggaagccgta cttccaagca tctatataag
    22201 aattaagtgc cccttgcctc atatagggag caaattctct ataatataac catctactat
    22261 atccatcttc ccaaacagca agaccacctg aagtttgctc caagtcctca gttgaaagaa
    22321 ctgtaaatgt atttgtacct gtcattgcaa gtaccttctt aaaatagatt gttgtaggct
    22381 cacatttttt atagtatatt tctttttttg tctattttat agcccatctc ctcaactggc
    22441 aatttttcga cctgaattac atttttccat aaaaaatgag acctttctag tctcatttag
    22501 tcattcttag tattttctaa atcgttgata gcgttcttcc agcaactctt ctagcggttt
    22561 ttgtgaaagt ctagccagct ccgtttggag ttcttttttg acactcttaa tcagttcttt
    22621 actagaaagt cctatttcag aaatcacctt atccaccacg tccatttcta acagttcatg
    22681 cgaagtgatt ttcatcagtt ctgctgcttc catggcgcga gtaccgtcct tccataaaat
    22741 ggaagcaaag ccttctggac tgagaatggc atagatagaa ttttccagca tccagacacg
    22801 gtccgcgaca gctagagcca gagccccgcc tgaaccacct tcaccgataa taatggcgat
    22861 aataggaact ttcaggtcac tcatttccat gagattgcga gcgatagctt ccccttgacc
    22921 acgttcttct gctccgacac caggataagc acctgctgta ttaataaagg tcacaactgg
    22981 acggccaaat ttctcagcct gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg
    23041 tggttggcca aaattccgtt tgaggttgtc ttgcaaactc ttgccttttt ggataccaac
    23101 aactgttaca gcttggtctc caagccaacc aataccacca acaactgcac catcatcacg
    23161 aaaagaacgg tcaccatgta attggataaa ttcatcaaaa atgcctgtcg caaagtccaa
    23221 ggttgtcaag cgactctgct cacgcgcttc tctgactatt tttgcaatat tcatctagga
    23281 ctccctccat gcaatctgac taggctagca atcgtatctg gtaagtctct tcttttgaca
    23341 atagcatcca caaagccatg ttctaatagg aattctgcct tttggaaatc ctcaggcaag
    23401 ctttcacgaa ccgtattttc aatcacacga cgcccagcaa aaccaaccaa gctctgtggt
    23461 tcagccagaa tgatatcgcc ttccatagcg aaagaagctg tcacaccacc agtcgttgga
    23521 tctgtcaaaa tggtcaggta aaagagacca gcatttgaat gacgtttaac cgccgcagag
    23581 atcttagcca tctgcatgag actcatgatt ccttcctgca tacgggctcc accagaggct
    23641 gtgaatagga caactggcaa tttttcgaca gtcgcatact caaacaaacg agtgattttt
    23701 tcacctacaa ccgtacccat agaagccatg ataaagttag aatccataat cccaagagcc
    23761 acagtctgac ctttaataag agcagttcct gtcacaacgg cttcatgcag acctgttttt
    23821 tcacgcatag atgccagttt cttttggtaa ccagggaaat gcaagggatc cttgctttca
    23881 atccctgtaa acaattcttt gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg
    23941 gcagaaatac gaaaggtata gctacagtgc ggacagatac gttcacttcc cagatccttc
    24001 tgatagatgg tatgcttaca gcctggacac tgggaaaata attcatctgg aacctctggc
    24061 ttagcttgag gtttttccct aaccgaacga ttgggattga ttcgaatata cttatctttt
    24121 ttactaaata gagccattga ttcccctttt cggtttaaac tcttaaagtc attttattct
    24181 ttttcttgat atttaggtaa gaaggtttcc atcaagaagg aagtatcata atccccagca
    24241 atgacattgc gatctgaaat gaggtcaagc tggaaatctg cattggtctg cactccttca
    24301 atctctaatt catagagggc acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg
    24361 tgtactatga ttttggcaat catactatca taataaggcg gaatggtata acctggataa
    24421 actgctgaat ccacgcgcaa gccaactcca ccacttggca gatagagatt agtaatctta
    24481 cctggacttg gagcaaagtt aaaggctggg ttttctgcat tgatacgaca ctcgatggca
    24541 tgaccgcgta ggacaatatc ttcttgctta acagacaaag gctgacctgc cgcaatgcaa
    24601 atctgttcct taacgatatc aacacctgaa acaaactctg ttactggatg ttctacctga
    24661 acacgagtat tcatctccat gaaatagaaa ttgctacttg cttcatcaag aagaaattca
    24721 atggttcctg cattctcata gccaacaaac tctgccgctc gaacagcagc agcacctatt
    24781 tcatgacgca gcgtttttcc gattgcaatc gagggacttt cttccaaaac cttttggtta
    24841 ttcctttgaa gagaacaatc ccgctcaccc aagtgaatca catgtccatg ctcatcacct
    24901 aggatttgaa cctcaatgtg ccgagctgga tagataaccc gttctatgta catggcacca
    24961 ttgccataat tggccttggc ctcactagag gcagtttcaa aggcagaaac gaggtcatct
    25021 ggtttttcaa ccttacgaat ccctttacca cctccacctg ctgaagcctt gagcataaca
    25081 ggatagccaa ttttttcagc aacaatcaaa gcttcttcag agttatgcac ttctccatct
    25141 gaacctggta taacaggcac acctgcttta atcatctgag cacgcgcatt gatcttatcc
    25201 cccatcatat ccataacatg accagatgga ccgataaact tgatacctac ttcttcacac
    25261 atggtcgcaa atttggaatt ttcactgaga aatccaaaac cagggtgaat agcttctgcc
    25321 tcagtcaaga ctgcagctga tagaactgca ttaatattga gataagactc tgttgccttg
    25381 ccaggaccaa tacaaactgc ttcatctgcc aaaagcgtat gaagagcttc cttatcagca
    25441 gttgaataaa ccgctaccgt cgcaatcccc aattcacgtg ccgcacggat aatacgaacc
    25501 gcaatttcac cacgattggc aattaaaatt tttcgaaaca tggagaacct ccttagttcc
    25561 caattgcaaa agtaaggata ccactggctg caagcttgcc atccacttca gcctttgctt
    25621 caaccacagc tatggtgcca cgacgtttta caaaagtcgc tgtcataacc aattggtcgc
    25681 ctggtacaac ttgcttcttg aacttaacct tgtccatacc agcgtaaaag accagttttc
    25741 ctttattttc aggttttgat aactccaaca caccagcagt ttgcgccaag gcttccataa
    25801 tcagaacacc tggcataact gggtattgag gaaagtggcc gttaaagaaa ggttcgttaa
    25861 tggtcacatt tttgatagca acaatggtat cctcgctcac ttccaagaca cggtccacta
    25921 gaagcatagg ataacggtgg ggaagagctt ctttgattcc ttgaatatcg atcatttgat
    25981 acgtaccaat cctttaccaa actcaaccat ttcttcgtta gagacgagaa tttccgttac
    26041 cacaccatcc ttaggagctg ggatttcatt catgactttc atggcttcga taattaccaa
    26101 tgtttgacct tttttgacac tatcaccaac tgtaacgaag gcaggtttat ctggtccagc
    26161 agccaagtaa accactccaa caagtggact ctctacaaga tttccctcac tagccacact
    26221 tgcttcagct ggagctggaa cttcttctgc tacagtctct gctggagcag atgtaggagc
    26281 tactggactc ggtgttgcta gaacgggtgc tggagcgact tgagttgcaa cttcaggcac
    26341 aggtctcgct tcattcttgc taaactgcaa ctcatccgtc ccatttttat aagaaaattc
    26401 tctcaaactt gactggtcaa attgagtcat caagtcttta atatcgttta aattcatact
    26461 tatctattct cccaacgttt gaaagcaaga actgcattgt ggcctccaaa accaaaagta
    26521 tttgaaatag cgtatggaat ttctttctcc aagccttgtc cataaacgac attagcttcg
    26581 atataatctg atacttcact tgtcccagct gtcattggta caaagttatg acgcatagct
    26641 tcgatggtga cgatagcttc tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac
    26701 ttggttgatg atacaggtac ttccttacca agaacagcta cgatagcacc actttctcct
    26761 ttttcattgg caggagttga cgttccgtga gcattgacat aggctacttg ctctggagaa
    26821 atctcagctt cttccaaggc tagtttgatg gccttgatag ctccctgacc ttctggatgt
    26881 ggagaagtca tgtggtaggc atcacaagta tttccgtaac caaccacttc agccaggata
    26941 gtagctccac gtttttcagc gtgttcaaga ctttctagaa ccaacatccc tgaaccttca
    27001 cccataacaa acccattgcg atccttatca aatgggatcg aagcacgagt tggatcctct
    27061 gtagtagaga gagctgttaa ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct
    27121 tctgttcctc ccaccaacat cacatcttgg aaaccaaact taatggagcg gaaggcatcc
    27181 ccaatcgcat catttgatga agagcaggca gtattgatag atttacaaac accgtttgca
    27241 ccaaaacgca tggctacatt cccagaagcc atatttggta aagcttttgg aagagtcatt
    27301 ggtttgacac gtttgggtcc tttttcatga aggcgaagta cctgatcttc aatttccttg
    27361 attccaccaa taccagatgc aacgataaca ccaaaacgat ccctattaag agcctctaca
    27421 tcaagattgg catgatttac agcctcttgg gctgcataca aggcatataa agaatagtta
    27481 tcaaaacggt tggtatcttt ttttacaaag tatttatcga acggaaaatc ttggatttct
    27541 gccgcattat gcacatcaaa gtcactatga tcaaattttg taatgccacc aatgccgatt
    27601 ttcccagttg ctaaactatt ccaaaattct tctggtgtat ttccgattgg agatgttact
    27661 ccataacctg ttaccactac tcgatttagt ttcattcttt tcacctctag ctttcgctac
    27721 atacttaagc caccatcaat ggcaaccact tgaccagtta gataatcttg gcctgctaaa
    27781 aatactgtca aatctgcaac ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct
    27841 agtgtagctt ccttaatctt atctgataag atagctgtca tatcagactc aatcattcct
    27901 ggagcaatca cattgactcg tatattccga ctagcgacct cgcgtgccac agacttggta
    27961 aagccaatca agccagcctt agaagcagca tagttagctt gaccaatatt ccccatcaaa
    28021 ccaacaacac tagacatatt aatgatagca ccttctctgg ctttcatcat cggtttcaag
    28081 actgattgtg tcatattaaa ggcaccagtc agattgacct tgagcacttt ttcaaaatct
    28141 gcttctgtca tcttgagcat aagagtatct tgggtaatcc ctgcattgtt gaccaaaaca
    28201 tctactgaac ccagttctgc aatagcttga tcaatcatac gcttagcgtc tgcaaaatct
    28261 gatacatctc ctgaaatggg aaccaccttg ataccatagt ttgaaaactc agcgagcaat
    28321 tcttctgaga ttgccccacg actgtttaag acaatgttgg ctcctgcttg agcaaacttg
    28381 tgggcgatgg caagaccaat tccacgactc gaacctgtaa taaagatatt tttatgttct
    28441 agtttcattt ttttcctttc aaaacttcta cttattttag tctatttttc taaaagtgct
    28501 actaaactcg cttgatcttc cacatgagct aagtgagcag tttgatcaat ttttttaaca
    28561 aaacctgaca agactttccc cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc
    28621 atgaccccaa tactttcata gaaacgaacg ggttccttga cctgacgcgt caagagctga
    28681 gcaatgtcct ctttttgcat cacagcagct tctgtattgc cgactagggg acaagtaaaa
    28741 tctgaaaaac ttacctgagc tagagtttca gctagtttct ggctagcagg ctcaaggaga
    28801 gcggtgtgaa agggccctga caccttaaga ggaatcaagc gtttggcacc tgcttcttgc
    28861 aaaagttcaa ccgctcgatc aactgcaacc acttctccag caatgacgat ttgtgcaggt
    28921 gtgttatagt tggctggagt aaccactcca agttcagaag ctttttgaca ggcttcttca
    28981 atgacctcta ctggcgtatt gagaactgct accatcttgc cagagtcagc aggagccgct
    29041 tcttccatat aggctccacg cttagctacc aaggcaaccg catcttcaaa atccaaggcg
    29101 ccgcttgcca ccaaggcaga gtattctcca agagacaaac cagcaaccat atcaggctga
    29161 tagccctttt cttgcaataa acggtagata gcaaccgaag tcgctagaat ggctggttgc
    29221 gtatagcggg tctgattgag tttgtcttct tccgtatcga tgagataacg taaatcataa
    29281 ccgagcacct gactcgctcg atcaatcgtt tctttgacaa tcggatactg atcatagaaa
    29341 tcccgtccca tccctagata ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc
    29401 atttcttaca actcctgccc agcgagaggc ttcttcttga attttcttag cggctccgta
    29461 atacaaatct tttaggattt cttcagctgt ttcttcttta gaaacaagcc ctgcgatttg
    29521 acctgccatg acagagccac catccacatc accgtgaaca actgctttgg ctagggcacc
    29581 tgctcccatt tgttcaaaga tttctaaatc aggatcttcc tgcttaaagg catctttttc
    29641 agccagttca aaatctctag tcaactgatt tttaatagca cgaacagcat gaccaaagtg
    29701 ctgagctgaa atcgtagtat caatatccct tgcttttaaa attttctcct tgtagtttgg
    29761 atgggcattc gactcttttg caactacaaa ccgtgtcccc acctgtacag cctctgcacc
    29821 tagcataaag ccagccgcag caccttcacc atccgcaatt cctcctgcag caataacagg
    29881 aatagatata gctgtggcta cctgtcgcac caaggtcatg gttgttaatt taccgatatg
    29941 ccccccagct tccattcctt ctgcaataac agcgtctgca ccgatttttt ccatgcgttt
    30001 agctaaagcg acactaggaa caacaggaat aacgattatc ccagcttcat ggaaacgttc
    30061 catatacttg cttggatttc ctgctcctgt tgtgacaact ttaacacctt cttcaataac
    30121 gagatccacg atatcttcca caaagggaga taagagcatg atgttgaccc caaagggttt
    30181 atcagtcaat gatttgattt tatcaatatt ggccttgaca acttctttcg gggcatttcc
    30241 cccaccgata attcctaatc ctccagcctt ggaaacagcc cctgccaaat caccatcagc
    30301 aacccaggcc atccctcctt ggaaaatagg atagtcaatc ttcaataatt ctgtaatacg
    30361 cgttttcata gtgcctccaa ccttccttgc ttacgtaata gttcgatttc accataattt
    30421 gacagtcaaa ctattaccta aacaagaggg agtgggtttc tccctactcc ttctactaat
    30481 attctgctta ttttgcttgc tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt
    30541 cattttctgc ttcgatttgg atatcaaaag catcttcgat ttctgagatt acttggaaca
    30601 agtccaatga atctgcgtcc aaatcatcaa aagttgattc aagtgttact tctgatgcgt
    30661 cttttccaag ttcttcaacg ataatttctt gtactttttc aaatactgcc atgataggac
    30721 tcctttaaaa taaatagttt ttttataaca atgtgttcac cacatgatta cctaaattgt
    30781 aagaatgagc gtgccccagg tcaagcctcc accgaagcct gatagaagaa cagtctggct
    30841 accatctaaa gggatgagac cttgttctac acactctgaa agtaaaatcg ggatactggc
    30901 tgcactggta ttgccatatt ccatcatatt ggctggaagt ttggctcggt caacaccaat
    30961 ttttctagcc atcttatcca aaatacggtc attggcttga tgaagtagca gataatccaa
    31021 gtctgtcacc tctataggag attcatcaat agtctgcttg atagacttgg ctacatctcg
    31081 aatggcaaaa tcaaagactg tgcgtccatc catcttcaaa aacgaatctg cactttcttg
    31141 atctgaaaat ggagaatgca aacctgaatg cccataagtt aaacactcgc tgcgacttcc
    31201 atcgctattg agactctcag ctaagaaatg ctcttgctcg ctagcttcta acaagacacc
    31261 accagcacca tctccaaaca acacagctgt tgatcgatcc gaccaatcga ctgccttaga
    31321 gagggtttca ctaccaatca ccaagccttt ttgaaagcga ccagaagcga taaacttttc
    31381 agcagttgaa agagcaaata caaatccact gcaagccgcg gttaagtcaa aagcaaaggc
    31441 tttattagcg ccaatattag cttgaacacg agcagctgta gagggcatca tcgaatctgg
    31501 agtaatggta gctaggatga taaaatccag ttcttttcct gttattccag cttttgccat
    31561 cagtttctta gcaacctctg tagccaaatc actggtagat tctgttcttg aaatatgcct
    31621 ttgtcgtatt cccgttcgac ttgaaatcca ctcatcattg gtatccataa tctgagccaa
    31681 gtcgtgattt gtaaccactt gctctggcac ataatgagca acctgactta tttttgcaaa
    31741 agccattatt tcaaatcctc caaaaattgg taaagattag tcaagccttt acccatgaca
    31801 gcaatttctt cctcgctcat gccatcaata attttttcta ccatggcctt gtggaagcgt
    31861 ttatgcagtc tatgaatcaa gcgacccttc tttgtcaaat gcagatgcac cacacgacga
    31921 tcctgttctg accgaactcg ctcaatgtag cccttacgct ctaaattgtt caaacttgtc
    31981 gtaacagttc caagagttac catcaactct tttgacactt gacttggagt cacatctgga
    32041 gccttaccga tgacattaat cgtatgcatt tctttgatgg agatatcctt aaaacgacta
    32101 cctctcaagt tcacttcctc aattacaagg acattgttaa atatagatgt taaatattca
    32161 ttgattcgtt ggtagtccat ttttcatatc cctccttctt caaaaaactt ttacaatcaa
    32221 aacatttgac agaaagaatt atatcaaaat tcaaagaatg atgcaagtat tttttatttt
    32281 cctgtaaatt taggtcttct tctctccgaa tgagctcgca ctccttcttt gaaatcctct
    32341 gtttgagcta aggatttctg taggttcagt tctaaagtag cgtaaccctg ccagtcttta
    32401 aactggctct cccaaaccaa cttcttaatg gcagcatagg aattacttga agcacgtctt
    32461 aattttttaa gaagctgttc tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa
    32521 accaaccccc attctagggc tttttctgcc gttaaagcct ctcctgtcat agctaattga
    32581 gcagcacgcg tcacaccgat actgcggctc aagagatgaa ttccccctgc atctggagcc
    32641 aaaccaacac caacaaaggc ttggataaac ttagccttat ccgtcgccaa acagaaatct
    32701 gccgcaacag ccatattcgc tgcggcacct gcaacagcac cgtcaacttc cattaaaaca
    32761 ggtttggcta tttgcttgat tttataagaa atcgtattga ccaactctgc gatttttgtc
    32821 aatgatggaa tatcatcctc atccactgcc cgcttcatct ctaccaaatc tcccccaact
    32881 gagaagacct ttccattggc attgattaag ataaaatgca cagctggatt ttcttctgcc
    32941 aaagtcagag cttctaaaat ctcctcacac atgggaatat gaaaaccatt tgcgacctca
    33001 ggacggttca aggtaaggat tgccaagtcc tcttcaagct gataaataat gtgttccatc
    33061 agggctcctt tttattttat aagcagttta tactcttcga aaatctcttt aaaccgcgtc
    33121 agcttccatc tgcaacctca aaacagtatt ttgagctgac ttcggctagc ttcctagttt
    33181 gctctttgat tttcattgag tgttaaatta tttcactgtc aaagtatatc ttttttagga
    33241 gcagaaagca agaaaaaatc gactgaaagt gtctcagccg ataagaaagg ctcgctttag
    33301 gctagaaagc atcttatttt cttcattgaa aaaagccttt ctttctgcta taatcgtata
    33361 aaatacttac tttaggagtt cttatgaaag ttgttaaatt tggaggtagt tctcttgcct
    33421 ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg
    33481 tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac taaggttacg gatgccctga
    33541 ttaaatacta ccgcgactat gttgcgggta acgatattag caagagccaa agctggatta
    33601 tcgaccgcta tgctgctatg gttagtgaat tgggactaaa accagctgtg ctagaaaaaa
    33661 tttctaaaag cattcacgcc ttggccactc ttcctattga agaaaatgaa tttctctacg
    33721 atactttcct agcagccggt gaaaataaca atgccaaatt gattgctgcc tactttaacc
    33781 aaaatggtat cgatgcacgc tatatgcacc ctagagaagc tgggattgtg gtcacaagtg
    33841 aacctggtca cgctcgcatc attccatcaa gttatgacaa gattgaagaa ttgacaaaca
    33901 ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac taaggaaaat caaatctgta
    33961 ctttctcacg tggaggttct gatattacag gttctatcat tgctgctggt gtcaaagctg
    34021 acctctatga aaactttacg gacgttgatg gtatctttgc agcccaccct ggtattatcc
    34081 accaaccaca ctcgattcct gagttgacct accgtgaaat gcgcgagttg gcctatgcag
    34141 gcttctcagt ccttcatgac gaggctcttc ttcctgccta ccgtggaaaa attcctctgg
    34201 ttatcaagaa taccaacaac cctgaccatc caggtactcg tatcgttcta aaacacagta
    34261 atgatgaatt tccagttgtg ggaattgctg gtgactcagg ctttgtcagc attaacatgt
    34321 cgaaatacct catgaaccgt gaggttggat ttggccgcaa ggttctgcaa atcctggaag
    34381 aacttaacat cggttgggaa catatgccaa caggtatcga cgatctttct atcattctcc
    34441 gttctcgcca actaactccc atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg
    34501 ctaaagtaga tcatgcagaa atcgaacacg acctttctat cattatgatt gttggtgaaa
    34561 aaatgaagag ccacatcgga gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa
    34621 tcaacatcca gatgatgtct caaggttcta gtgaagtttc tattatgttt gttgtcaata
    34681 aagaccaaga gaaagcagca attaaagccc tctacaatgc cttttttgga gaaagtaagg
    34741 aagactaagc atggcccaat cacttaacaa aacagtactc ctcagtacga caggcacttc
    34801 ctacctctct atcgctggga aagttgggaa attccttgtc ggagatcagg ctttggaatt
    34861 ttacccagat gtcaatgtcg aacaatttat ccagattcct tggagccata tcaatcagat
    34921 tggagccaat gtcactggat gcaaaatcag ccgccacttc gaagtcttta cagacaaagg
    34981 aaaattcctc tttgcttcaa aagactcagg tgccattctc aaaattgcac gcgaaaaact
    35041 aggcaatgac aaggtcgtca aacttccgac cctgattcag acaattagcc aaaaatttaa
    35101 aaatctattt gcaaaaaagt agaaacttta gtataatcat agcaacggat aagtaggtta
    35161 tcttcttctt tcagaaagtc tgcgggtact gcgagcagat aggagggata ggtgaaattc
    35221 taccgttagt aacaattaca tacacaatca agtgcacacc tgtgaagttg gatggaaccg
    35281 tggccctgcc actccaacgt tttgtcaggc gtgctttttt cataaaggag ttcttatgtt
    35341 agatatcaaa cgtattcgta cagattttga agctgtcgca gaaaaattag ctacacgtgg
    35401 tgtagatgct gctgtcttga atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt
    35461 ggtcaaggtt gaaactctca aagcagaacg taacacagtt tctgctgaga ttgcccaagc
    35521 taagcgcaac aaggaaaata cagatgacaa gattgctgcc atgcaaaatc tatctgctga
    35581 ggttaaagcc ttggatgctg aattggcaga aatcgatgct aaattgacag aatttacaac
    35641 gactcttcca aatatcccag ctgacagcgt tcctgttggg gctgacgaag acgacaatgt
    35701 ggaagttcgc cgttggggta ctccacgcga gtttgacttc gaacctaaag ctcactggga
    35761 tctcggtgaa gaccttggta tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg
    35821 cttcctcttc tataaaggcc tcggtgctcg tttggaacgt gctatctaca actttatgtt
    35881 ggatgaacat ggaaaagaag gctatactga agtcatcaca ccttacatag tcaaccatga
    35941 ttctatgttt ggtactggtc agtatccaaa atttaaggaa gatacttttg aactcagcga
    36001 taccaacttt gtcttgattc caactgctga agttcctctg acaaactact accgtgatga
    36061 aatcttagac ggcaaagatc ttccaatcta cttcactgct atgagtccgt cattccgttc
    36121 tgaggctggt tctgccggtc gtgatacgcg tggcttgatc cgtttgcacc aattccacaa
    36181 ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac gaagaattgg aaaaaatgac
    36241 agccaacgct gaaaacattc ttcaaaaact caaccttcca taccgtgtcg ttgctctctc
    36301 tactggagat atgggcttct cagctgcgaa gacttacgac ttggaagtgt ggattccagc
    36361 acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg
    36421 tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg aaactccttc ataccttgaa
    36481 cggttctgga cttgcagttg gacgtacagt ggctgcaatt cttgaaaatt accaaaatga
    36541 agatggttct gtgaccatcc cagaagcact tcgtccatac atgggtggag ctgaagtcat
    36601 caaaccataa aaaataaggt ttagctattt ctagctagac cttttttcgt aaccaaatca
    36661 gataagcacc tagtacaaag aataaaatag ttaggcatat aatggtttca gccaatacca
    36721 ggtaatccag aaatggaagt ttcaaaattc cctgagccat cttgagcgag gtcgctgtga
    36781 taatggttgg gaaggtgagg gctgagaagg ctggttgaaa accttgtttt aaaatgttgg
    36841 gcagacgagt taaaacaaag aaaaagaagg attgagaagc caaaatcatg acaatcaaga
    36901 cccaagtcgg caggctggtt cctcctactc gaactagaga agccaagagt agagagaaag
    36961 gagcacagta gattccttct tgtccaagca aggctagtgg gagtggatgt ttctttaaat
    37021 cgctataaat aaggggatag agatagaagg tcaagagaaa accaaaactc aaggtcgcat
    37081 aggcaatttc gataatacct accagaggat aggtcaaggc agccactgct atccccacat
    37141 agagaaccgt ccagcttgga gtggcatgaa ccctccgccc tggacaagca aacttgatgg
    37201 taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta
    37261 ccaaaggaag ataagagaat acgcgaaaga cataggtcga taaaatcatc ccagccatag
    37321 gaaaggttgc cattcctgac aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc
    37381 aattaaagag atgcagaatt agaaagtaaa tccataaaac caaaccagtc agactaaaaa
    37441 gatgggatag aaccggcaac gtatctaaaa taagatttcc agctcctgcc aaacctagca
    37501 aacaacctga aaatactaag gggagttttt tcatcctaac ctccaataat catgttagtt
    37561 tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa acgaagtccg cttatttcag
    37621 acttcatttt actcagatat gaattaggca taaggttgca attctggatt aattggtgta
    37681 ttagctaagt tgttggcata gttacagagg attgctaggc tgacaccaaa aaccacatcc
    37741 aaggcatttt gttgagtgta gccagcttct aaaaactcag acaaggcttc atctcctaca
    37801 cgacccttgg tattgataac tgccaaggta aacttagcta gggtatccaa tttaggatct
    37861 gtttcaattg gagtacgatt gcgaagagct tgaatcaagt catcattcat ctggatttgt
    37921 ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac aaccattggt cacggctgcc
    37981 gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag
    38041 acaatttggt aggcttctaa aacagtcggg gcattggcca agagaccgat taggttggga
    38101 atatagccat tgttgtcttt ttctactgtt tcaagaattt ctttcacttc tgctggtgct
    38161 gactctactg tatggatagt aaatgttgtc ataagatacc tcttttctta ttattgacac
    38221 taatattatt ggaaaatctt ataaaatcct gattcctaag tttatctaag ataaagcttt
    38281 attctctcat aagattttcg ttgttatatt agtttatcac acttccaatc acttgcataa
    38341 tatatattat atatcaggct gataaaaatt atttataggc aaaaaaatca cacgagctgt
    38401 gtgattccat tatttgtcaa aatacttttt agtttcagca ataacgactg gcgacaagac
    38461 caagagggca atcaagtttg gcagagccat caaggcgtta acgatatctg cgataatcca
    38521 gaccatatcc aactcgataa atcctcctaa caagaccatg agcacaaaaa ccacacggta
    38581 gagccagata aagcgaaccc caaagaggaa ctcaaaacag cgttctccgt aatagttcca
    38641 acctagaatc gttgtaaagg caaaaagtac aaggaagatg gtcaagaggg caggcccaaa
    38701 gtgtgaaaag actgttgaga aagctgactg agtcaaggca accccattca agtcaccact
    38761 ccaaactcca gttaccaaga tggtcaaacc agttagagta caaatgatga gggtatcaat
    38821 aaaggttcct gtcatggaaa tcaaaccttg ctctactggt tcatttgtct tggcagctgc
    38881 agctgcaata ggagcagaac ccagaccaga ttcgtttgag aacacaccac gcgccacacc
    38941 attttgaata gccatccgaa cgctagcacc agcaaatcca cctaccgcag caaggggact
    39001 aaaagctgag gtaaagacta aagcgattgt gccagggatt tttccaatat taaagaaaat
    39061 aactgtaaga gttcctaaga tataaatgat ggccataaaa ggaacaacag tagttgaaac
    39121 cttagaaata gacttgagtc caccaaagac tgcaatcgct acaaagacag acaagacgag
    39181 agctgtgatg gctggcgaaa tcgtcgttgt attttggata gattctgcaa tcgagttgac
    39241 ttgggtgaag gttccgattc ccaagagagc aaccaatact cctgctactg caaacaaaac
    39301 agcaagtggt cgccactttt ctcccatccc tagaaggata taatgcatgg gacctcccgc
    39361 tactgcacca tggtcgtcct tggtgcggta tttgatggcc aagagtcctt ccgcatactt
    39421 ggtagccatt ccaaagaaag ccgccatcca catccaaaat agagctcctg gtccaccaac
    39481 cttgatagcc gtcgcaactc ctatgatatt tcctgttcca acagttgatg ccaaggctgt
    39541 acacagagct gcaaaactgg atacatcacc atgtccctta tcctggataa aaataagctg
    39601 aaaagccttg ggcagacgca aaacctgcaa gagtcctagc cgaatagtta ggtaaatccc
    39661 tgttccgacc aataaaatca agaggggcgg tccccaagca aaagcatcga ttgatttaag
    39721 caattctaac atttccttct cctatcgttt caaccccaaa agaaagagca catgcaagat
    39781 acatgtactc tggaatgctt agataaatgc taaaaagcgg tctatcctag ctctgtcctt
    39841 ttacctgaga gtttgagcag ttgcctgcct tgccccttcg gtgcctttac ggtctctcca
    39901 gagttccgtc catttacagt catggaaaat caaacgattc cccacttcta ttaaacttca
    39961 ttcggtgttg gtatttaatt gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg
    40021 tttattagta aaaattagtt caacagtttt tactttataa agtccagaat actgctatcc
    40081 tttaaaagtg acaatagtcg caccactgcc tccagcattt tgtggggcat agccgaaact
    40141 cttgacatgt ttgtttcttt gcaagtattt ggtaactcct tcacggatga ctcctgttcc
    40201 gataccatgg atgatatcaa cttgagccat attgttaagc aaggcttggt cgatgaaggt
    40261 atctagctca ttcatggctt cttcatagcg cttgcctcga agatccagtc tagcttgagg
    40321 tcctcgccca gaagttcgtt tcacaacatt gacctgtttc ttcttgactg gtttttcttg
    40381 ctgggcttga acaagatcaa actctttctc ttccaaggtc atcttaatca agccaacttg
    40441 ggcttcccag cggccgtcct tgagttgact ggtcaaggta ccacgctgac cataactgag
    40501 aaccacgata tcatctccca cctttggagc tcgttttttc ttggcctttt gaaggacctt
    40561 gtttttagac aagtccactt tttcaggagc caattttttc aacttggcct tggcttcaat
    40621 gatttcgtgg ggcttgagtt gggatttact gtggagattt ttgagaatct ggtcactttc
    40681 acttagggcc atatccacaa tctcagcagc ctgttcacgc gccttgttaa gctcggtttc
    40741 cttttcacga ttaagctcgt tgtagagttt ttttagcgca cggttcatct tgagattttc
    40801 ttgctccacc tcacggatat tgtccaagcg tttgcggctt tccagcgtct gctcttctaa
    40861 ttgctcaatg atacgattga cgtcattgtc ctgatcgatc tgctgactgg catctcctac
    40921 gataacttca gataggccta gacgtttggc aatttcaaag gcattacttc ggccaggaac
    40981 accctgcata aagcgatagg tcgggcgaag agttgcagta tcaaactcca tactggcatt
    41041 ttgcacaaag gctgtctcaa taccgtaggc cttgagttct ggatagtggg tcgtcgccat
    41101 ggtcttgatt tgacgcaggc gaaggtcctc cagaatagcc atggcaaggg ctgctccctc
    41161 ttggggatca gtaccagccc ccaactcatc caaaagtaag agtgaatgtt ggttgacctt
    41221 gccaagaata tccacgatat tggtcatatg gctagagaag gtagacaagc tctgctcaat
    41281 agactgctca tctccaatat cagcaaagat ttcttcaaaa ataccaacac gacttccctt
    41341 gtctgctaaa atcggcaatc ctgactgggc catgacctgt gtcaagccca gagttttgag
    41401 catgatggtc ttcccacctg tattgggacc tgtaatgaca atagctgtta aatcttgacc
    41461 aaaatagaca tcatttgcga cggcattttt gaccaaagga tggcagacat ggagcagttg
    41521 aatctcttga ttttctgaca gctgaggcac gactgcttgt ctttcttgga taaatcgaac
    41581 cttggcacga atcaagtcca aatgaccgat aatccaagcg tcattagcaa tctcagccgc
    41641 atgagggcgg acacgctcag aaatttcttg gagaatgcga agcatttcat agcgctcatc
    41701 tgctcgcaga ctagcaattt cttcgctcag tttgactacc tcacgtggtt cgatatagac
    41761 ggtgtttcca ctagcagaaa tatcatgaac gacacctgca atcttattgc ggtaggtgtt
    41821 tttgactggt aaaacctgac ggccatttct gctagcaaca attccttccg tcaacatctg
    41881 cgctttttgc ttgagcaagt cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat
    41941 ttttcgacgg attcgcgcca attcttcact ggcaaaattt tcaatgaaac ccgcatcatt
    42001 aaaggcctga agatttcctt gtaattgcgg aaaatcatgt aatttctcaa accaaagggc
    42061 taattcttcc aagctgacat tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc
    42121 aagaagcacg cgtttcaaga gtaggaactc ctcgatattg agatccgctc ccatctccaa
    42181 cctcttgcag actcctgcaa tttccttagt tgagagaata gtaaaatgcg gttgctcgac
    42241 gaaaagagcc tgcatttctt tcatctcagc aaaagcctgt ttgattttat ctgctttggc
    42301 agtcggagcc agctgtctca attgctccaa gccctgctcg gtcaacaaat gaggctcaaa
    42361 caaggccttg accttatcga actctaatgt ttctaatatt ttcttattca tctttatttc
    42421 cttgtctttg aatgtctagg tgtggtagct ttttacattc tgatagattc gagtcaaatc
    42481 tgtaaacaaa gggctaggaa aactcctgcc ctttttatcc gattaaattt gtcacccaga
    42541 tttgtttgag ccaactggtt gttatcggta tgctctggat gatgtgtttt gcgacgatac
    42601 tcttttcaag aggattttgt ataactgcca tggggatggt cgccaagatt gtcaaggcca
    42661 tttgcaagac aaataaggtc accaacatag acaagatacc tgctgaaact tggaacaact
    42721 taccacccag ttttttgcta ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc
    42781 tatagacaat cccaaataca agcaagtagc cgatacctgc ataaaagacc ttatccagct
    42841 gaaagagttg atccgatggg aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag
    42901 ggagcaataa atggaattgc tctccaagcc ccttataaaa ctggccagcc ataaaagccg
    42961 atgccatggc tgaaatcagg taataaacct gtaagagcag gcctctccga tagccgatat
    43021 aaaatcccca aaccaagacc aatagaagaa ggaatgaaat cataaggaat cctcaatctt
    43081 gctctgttct tgcttacaag tcacaagctt gtgacggagt tcttctagct cttgctcctt
    43141 atcgtcaaat tcaatctcac ggctgagctg agttgataaa cagttgactg ccaacaaaag
    43201 agcgattgtt tcatcatctg cgctaggcat ttgttcttta attgcttggt atttttctgt
    43261 cgcaacctta gcgatttcct ccataaaaag gttatcatgt tcgcttgtca aggttaacga
    43321 ttttttcccg aatgtaaatt tgaatcgatt tagatttgcc ataaaattca cctcacgata
    43381 ttataccaaa attcgctaat tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa
    43441 tagaaactat ggcaagtatc acactcacac caagcgaaaa ggatattcag gcttttcttg
    43501 aacactatca aaccagtctg gctcctagca agaatcccta tatccgctac tttttgaaac
    43561 tacctcaagc aacggtttct atctatactt ctggaaaaat cttgcttcag ggtgaagggg
    43621 ctgaaaaata cgccagtttc tttggctatc aagctgtaga gcaaaccagc ggacaaaatc
    43681 ttcctttaat tgggacagat gaggtgggaa atggttccta ctttggtggg cttgcagttg
    43741 tggctgcctt tgtcacatct gaccagcacg actttttacg aaaactcggt gtgggggatt
    43801 ctaagactct gaccgaccaa aagatccgtc agattgctcc tattctcaag gaaaaaatcc
    43861 agcaccaggc actccttctc tcacccagca agtacaacga ggtcatcgga gaccgctaca
    43921 atgctgtttc ggttaaggtt gccctccata atcaggctat ctatctcctc cttcaaaaag
    43981 gtgttcagcc tgagaaaatt gtgattgatg cctttaccag tgctaaaaat tatgacaagt
    44041 acttggcaca agagaccaat cgtttcagca atcctatcag cttagaagaa aaggctgagg
    44101 gcaaatactt ggctgtcgca gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc
    44161 ttgaaaattt gggacgagaa ctgggttatc agcttccaag tggagctgga acggcctctg
    44221 acaaggtggc tagccagatt ttgcaagcct atggtatgca gggactcaac ttctgcgcta
    44281 agctacactt taaaaatact gaaaaagcga aaaacgctta gaaaggtaag ttatgaattt
    44341 atttaaaaat ttcttaaaag agtggggatt attcctcctg attctgtcat tactagcttt
    44401 gagccgtatc tttttttgga gcaatgttcg cgtagaagga cattccatgg atccgaccct
    44461 agcggatggt gaaatcctct ttgttgttaa gcacctccct attgaccgtt ttgatatcgt
    44521 ggtggcccat gaggaagatg gcaataagga cattgtcaaa cgtgtcatcg gaatgcctgg
    44581 cgataccatc cgttacgaaa atgataaact ttacatcaat gacaaagaaa cggacgagcc
    44641 ttatctagca gactatatca aacgcttcaa ggatgacaaa ctccaaagca cttactcagg
    44701 caagggcttt gaaggaaata aaggaacttt ctttagaagt atcgctcaaa aagcccatgc
    44761 cttcacagtt gatgtcaact acaacaccaa ctttagcttt actgttccag aaggagaata
    44821 ccttctcctc ggagatgacc gcttggtttc gagcgacagc cgccacgtag gtaccttcaa
    44881 agcaaaagat atcacagggg aagctaaatt ccgcttctgg ccaatcaccc gtatcggaac
    44941 attttaagag acctaagagg ccgagaatca caaatctcag cctcttcttc tatcgtgaga
    45001 agtgattgtt tattgacaaa tactcaatga aaatcaaaga acaaactagg aagctagccg
    45061 taggctgctt aaaacagtgt tttgaggttg tggatagaac tgacgaagtc agctcaaaat
    45121 actgttttga ggttgcagat ggaagctgac gtggtttgaa gatattttcg aagagtataa
    45181 aataaaaaca atcccaactc tcacctattc atgcaaagga attttatgga agtttatttt
    45241 tcaggaacca ttgaacggat tatttttgaa aatcccagca atttttatcg catcctcctc
    45301 ctagaaatcg acgatacgga cgcagaggat tttgatgatt ttgaaatcat tgtcacagga
    45361 accatggctg atgtaattga gggcgaagac tatatttttt gggggcaaat tgtccagcac
    45421 tccaagtatg gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag
    45481 ggattggtca agtacttttc aagtagccat ttcaagggga ttggtctcaa gacagctcag
    45541 aaaatcgtag atacctatgg cgaaaatacc attgatgaaa ttttgcaaca cccagaaaag
    45601 ttagaaggca tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt
    45661 ctcaactacg gaacggagat ggttttggcc aaactagcca actacggcat tcccaacaaa
    45721 ctagcctttc agattcaaga cttttacaag gaagaaaccc ttgatgtggt tgaaaattat
    45781 ccctaccagc tggttgagga tatcaagggt ttgggcttta caattgctga ccaactagct
    45841 gaggaactag gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct agttcacagt
    45901 ctttttcagg cctgtatgga aacaggggac acctatgttg aagcacggga tttgctggaa
    45961 caaaccctta ctctccttga gtcttcccgt cccgtggaac tagaccccag ccaagttgcc
    46021 caagagctct cctacctgat cgaagaagac aaggttcagc agattgatac caagatcttt
    46081 gacaacagcc tctttttcgc tgaggaaggc atccgcagtc acttggttcg tatccttgaa
    46141 aaaggaaaac agaagagtca tgatttagaa accattcaaa aacatatcac tactatcgag
    46201 gaagagctgg gaattgagta tgataacatt caaaaacagg ctatctgtga cgctatccag
    46261 aacaaggtct ttatcctgac aggtgggcct ggtactggta agacaactgt tatcaatgga
    46321 atcatcgctg tttatgccct tttagaagga cttgacttca ggaagaaaaa caatctgccc
    46381 attcttcttg ctgctccaac tggacgagcc gctcgccgca tgaatgaatt gacaggtttg
    46441 cctagcgcga ccatacaccg ccacttggga atgacaggtg acgatgatac cagtcatctg
    46501 gaagattacc tagatgctga ctttatcatc gtggatgaat tctctatggt ggatacttgg
    46561 ctggccaatc aactcttctc caatatctct tctaacagta agatcctcat cgtgggtgac
    46621 agtgatcagc taccttctgt cagtcctgga caggttctag cggatctgct tcatattcct
    46681 ttgattcctc agactcgctt ggaaaaaatt tatcgacaaa gcgaagaatc aaccatcgtc
    46741 accctagcta gtcagattcg acagggcatc ttgccagctg atttcaccca aaaaaaagct
    46801 gaccgttcct actttgaaat tgctagtggc catattcctg ccactattga aaaaatctta
    46861 gatgccgccc tcagaaatgg tattcctgcc cgtgatatcc aagttctggc tcctatgtac
    46921 cgagggacgg cagggattga tgctatcaat cagctcatgc aagacctgct caatccccca
    46981 caaaaagatc aactcagttt tgaagctcct cagtgccact atcgtaaggg agacaaggtc
    47041 attcatttgg ttaacgatgc tgaaatcaat gtctttaatg gggatttagg agctatcaca
    47101 gacctgattc ctggtaaata caccgaatcg aaacaagacg agattgtcat tgattttgat
    47161 ggtaatgaag tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg
    47221 agtattcata agtctcaggg aagtgagttc ccagttgtca tcctaccgat tactagtgct
    47281 agccgacgta tgctggagcg aaatctcatc tacacagcca ttacacgtgc caaaagcaaa
    47341 ctcatcttac taggcgaatt acaagccttc gactatgcta cccaacacat cggaactgcc
    47401 cgaaaaacct atctgattga acgcttcagt gatctactgg agaatgttga agaaaagcaa
    47461 caagctgtct ctgaaacagt cacatcaagt gcctctgaac aatcctacat cctaaccgaa
    47521 gaaaactggg acagcattcc agccatgatt gggattacag acacagacct caaagagatt
    47581 tttggaaaat agtacatcag aaaacccacc aattcaggtg ggttttctgt ttattaagat
    47641 tattttactg ttgctgtgct tgtgatcaat tcaacagctt ttttgatagt gatatcatgt
    47701 ttcaacatgt cagctgaaag caagttttga acttgtgcaa cttccatgtt gtagtctgct
    47761 gccaattgct caacttcttt ttggatttct tcttctgaag catcaaatcc ttcagctttg
    47821 gcaactgctt cgataacaag gttagtctta gtacgtgact cagcttctgc ttggtattgg
    47881 ttgtgaaggt cttcttgagt agttccagtg atttggaagt acatgtcagg gttgatccct
    47941 tgacgttgca agttcccaag gaattcattt actgaacggt gaacttcttc gtggatcatt
    48001 tcttctggaa gttctacgat ttcagcattt tctacagctg tatcaattgc tgcaccttca
    48061 actgcatctt tgtaagcttc ttctttagca gtagccaatt ctttgcggta tttttctttc
    48121 aagtcagcaa gtgtttcaac ttcttcatca atgtcttttg caagttcatc gtcaagagct
    48181 ggaacttctt tagcttttac ttcgtggata gttgtcacga atttagcttc tttacctgca
    48241 aggtcttctg cttggtagtc ttctgggaat gttacgataa catcaacggt ttcgccagct
    48301 gagtgaccta ccaattggtc ttcgaaacca gggatgaatt gacctgaacc aagtccaagt
    48361 gagaagtttt caccttttcc accgtcaaat tcaacaccgt cgatagaacc aacgaagtcg
    48421 atcacaacag tgtcgccgtt ttcagcagca gcttccttga taaccaattc agccaggttg
    48481 ttgcgttcgc gttcgatacg ctcttcaaca tcagcgtcag ttacttcttt ttctacatca
    48541 actgatactt caaggttttt gtagtcaccc aattttactt caggttttgt aacgacttca
    48601 gcagcgataa cccagtcttg acctttttcc attgaagtta cgtcaatttt tggttgggca
    48661 accacttcaa gaccagcttc ttttacagct gcttcataag cgtttggcaa aagagcgttc
    48721 attgcatctt gataaagagc ttcttcacca aatttttggt cgaagatagg gcgtggaagg
    48781 tgacctttac ggaaacctgg aacattaaga gatttcttca ctgacttgaa gacacggtcc
    48841 aattctggtt tgatttggtc ttgagagata gtgaaagtca agacaccacg gtttgtttct
    48901 ttgttttcaa atgatacaga cattctgtca tttctcctta aaatttttta aatacagtct
    48961 attataacat tttctataaa taaaatctag actaatgcag ccaattatag acaacaagcc
    49021 tttttcctaa ctaaaacact cataaagtat agacaatttt agactacttt ggatatcttt
    49081 tggttagtca ttttccaaaa ctaatttatc taatttttca gttatatagt a
//
LOCUS       DAVMCN010000010        47549 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVMCN010000010 DAVMCN010000000
VERSION     DAVMCN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.010"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            49..1038
                     /gene="manX"
                     /locus_tag="VYP85_000712"
     CDS             49..1038
                     /gene="manX"
                     /locus_tag="VYP85_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1881259.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            1066..1869
                     /locus_tag="VYP85_000713"
     CDS             1066..1869
                     /locus_tag="VYP85_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1881260.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            1893..2804
                     /locus_tag="VYP85_000714"
     CDS             1893..2804
                     /locus_tag="VYP85_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1881261.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2860..4194)
                     /gene="pepC"
                     /locus_tag="VYP85_000715"
     CDS             complement(2860..4194)
                     /gene="pepC"
                     /locus_tag="VYP85_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1881262.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(4411..5133)
                     /locus_tag="VYP85_000716"
     CDS             complement(4411..5133)
                     /locus_tag="VYP85_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1881263.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(5446..5676)
                     /locus_tag="VYP85_000717"
     CDS             complement(5446..5676)
                     /locus_tag="VYP85_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1881264.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(5686..6927)
                     /locus_tag="VYP85_000718"
     CDS             complement(5686..6927)
                     /locus_tag="VYP85_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1881265.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMESLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(7122..7400)
                     /locus_tag="VYP85_000719"
     CDS             complement(7122..7400)
                     /locus_tag="VYP85_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1881266.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPTRY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(7393..7656)
                     /locus_tag="VYP85_000720"
                     /pseudo
     CDS             complement(7393..7656)
                     /locus_tag="VYP85_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            complement(7758..12149)
                     /locus_tag="VYP85_000721"
     CDS             complement(7758..12149)
                     /locus_tag="VYP85_000721"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1881267.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFNVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLDRLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEVYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(12253..14334)
                     /gene="fusA"
                     /locus_tag="VYP85_000722"
     CDS             complement(12253..14334)
                     /gene="fusA"
                     /locus_tag="VYP85_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1881268.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(14759..15229)
                     /gene="rpsG"
                     /locus_tag="VYP85_000723"
     CDS             complement(14759..15229)
                     /gene="rpsG"
                     /locus_tag="VYP85_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1881269.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(15249..15662)
                     /gene="rpsL"
                     /locus_tag="VYP85_000724"
     CDS             complement(15249..15662)
                     /gene="rpsL"
                     /locus_tag="VYP85_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1881270.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16079..19921
                     /gene="spuA"
                     /locus_tag="VYP85_000725"
     CDS             16079..19921
                     /gene="spuA"
                     /locus_tag="VYP85_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1881271.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            complement(20021..21070)
                     /locus_tag="VYP85_000726"
     CDS             complement(20021..21070)
                     /locus_tag="VYP85_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1881272.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            21127..21264
                     /locus_tag="VYP85_000727"
     CDS             21127..21264
                     /locus_tag="VYP85_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881273.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEISNHTYGKATLTWFEEI
                     F"
     gene            complement(21341..23149)
                     /gene="glmS"
                     /locus_tag="VYP85_000728"
     CDS             complement(21341..23149)
                     /gene="glmS"
                     /locus_tag="VYP85_000728"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1881274.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(23341..24720)
                     /gene="bglA"
                     /locus_tag="VYP85_000729"
     CDS             complement(23341..24720)
                     /gene="bglA"
                     /locus_tag="VYP85_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1881275.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            complement(24820..26673)
                     /locus_tag="VYP85_000730"
     CDS             complement(24820..26673)
                     /locus_tag="VYP85_000730"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1881276.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(26686..27945)
                     /gene="rseP"
                     /locus_tag="VYP85_000731"
     CDS             complement(26686..27945)
                     /gene="rseP"
                     /locus_tag="VYP85_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1881277.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(27967..28770)
                     /locus_tag="VYP85_000732"
     CDS             complement(27967..28770)
                     /locus_tag="VYP85_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1881278.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIVAMLAMHE
                     LLKMRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(28779..29537)
                     /locus_tag="VYP85_000733"
     CDS             complement(28779..29537)
                     /locus_tag="VYP85_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1881279.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(29768..30340)
                     /locus_tag="VYP85_000734"
     CDS             complement(29768..30340)
                     /locus_tag="VYP85_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1881280.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEELDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(30321..31292)
                     /gene="ruvB"
                     /locus_tag="VYP85_000735"
     CDS             complement(30321..31292)
                     /gene="ruvB"
                     /locus_tag="VYP85_000735"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1881281.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNDLEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            31454..31546
                     /locus_tag="VYP85_000736"
     CDS             31454..31546
                     /locus_tag="VYP85_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1881282.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(32298..33555)
                     /gene="ltrA"
                     /locus_tag="VYP85_000737"
                     /pseudo
     CDS             complement(32298..33555)
                     /gene="ltrA"
                     /locus_tag="VYP85_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34295..34711)
                     /locus_tag="VYP85_000738"
     CDS             complement(34295..34711)
                     /locus_tag="VYP85_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881283.1"
                     /translation="MITIKKQEIVKLEDVLHLYQDVGWTNYTHQTEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPSYQRQGIGSSLMKEALGNFKEAYQVQ
                     LATEETEKNVGFYRSMGFEILSTYDCTGMIWINREK"
     gene            complement(34723..35418)
                     /locus_tag="VYP85_000739"
     CDS             complement(34723..35418)
                     /locus_tag="VYP85_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881284.1"
                     /translation="MPVNEYGQMIGESMEAYTPGELPSFDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQESVADMEELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLACYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLGFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKARLEIWLRPENF
                     DKNGRQHKSLREL"
     gene            complement(35612..38113)
                     /locus_tag="VYP85_000740"
     CDS             complement(35612..38113)
                     /locus_tag="VYP85_000740"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1881285.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLNASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEISLADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            complement(38568..39656)
                     /locus_tag="VYP85_000741"
     CDS             complement(38568..39656)
                     /locus_tag="VYP85_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1881286.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(39674..40342)
                     /locus_tag="VYP85_000742"
     CDS             complement(39674..40342)
                     /locus_tag="VYP85_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1881287.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            complement(40361..42799)
                     /locus_tag="VYP85_000743"
     CDS             complement(40361..42799)
                     /locus_tag="VYP85_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1881288.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(42950..44248)
                     /locus_tag="VYP85_000744"
     CDS             complement(42950..44248)
                     /locus_tag="VYP85_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1881289.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(44265..44573)
                     /locus_tag="VYP85_000745"
     CDS             complement(44265..44573)
                     /locus_tag="VYP85_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1881290.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(44619..44939)
                     /locus_tag="VYP85_000746"
     CDS             complement(44619..44939)
                     /locus_tag="VYP85_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1881291.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(45134..46114)
                     /locus_tag="VYP85_000747"
     CDS             complement(45134..46114)
                     /locus_tag="VYP85_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1881292.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(46127..46873)
                     /locus_tag="VYP85_000748"
     CDS             complement(46127..46873)
                     /locus_tag="VYP85_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1881293.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            46995..>47549
                     /locus_tag="VYP85_000749"
     CDS             46995..>47549
                     /locus_tag="VYP85_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEV1881294.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIP"
BASE COUNT        14020 a        10827 c         8622 g        14080 t
ORIGIN      
        1 aaagttttct taaatgaaaa ctaaaacaaa aaaggaggaa tgacaataat gagtatcgga
       61 atcattattg cgagccacgg cgaatttgct gcgggtattc atcagtcagg atctatgatc
      121 tttggtgaac aagaaaaggt tcaagttgtg acctttatgc caaatgaagg tcctgatgat
      181 ctatacgcta agtttaataa cgctgttgct gcatttgacg cagaagatga ggttctagtt
      241 ttggctgacc tttggagtgg ttctccattt aaccaagcta gtcgcgtgat gggagaaaat
      301 cctgagcgta agtttgccat catcacagga cttaacttac cgatgttgat tcaagcctac
      361 acagagcgcc tcatggacgc tgctgcaggt gtagaaaaag tcgctgctaa tatcattaaa
      421 gaagccaaag atggcatcaa agctcttcca gaagagctaa atccagttga agaagttgca
      481 agcgctgcag ctgctccagt tgcccaaact gctatcccag aaggaactgt tatcggagac
      541 ggtaaattga aaatcaatct tgcccgtctt gacacacgtc tacttcacgg tcaggttgca
      601 actgcttgga ctccagattc aaaagcaaat cgtatcatcg ttgcttcaga taacgtggct
      661 aaagacgacc ttcgtaaaga attgattaaa caagcagctc caggtaatgt caaggctaac
      721 gtggttccaa ttcaaaaact gattgagatt tcaaaagacc cacgttttgg agaaacacat
      781 gcccttatct tgtttgaaac acctcaagat gcccttcgtg ccatcgaagg cggcgtgcca
      841 atcaagactc ttaacgttgg ttctatggct cactcaacag gtaaaacatt ggtcaatacc
      901 gttttgtcta tggacaaaga agatgttgct acatttgaaa aaatgcgtga cttgggtgtt
      961 gaatttgatg tccgtaaagt accaaatgat tctaaaaaag atttgtttga cttgattaac
     1021 aaagccaatg tcaaataagc cattatttat gaaaggattt taaacatgtc tattatttct
     1081 atggttttag tagtcgttgt agccttcttt gcaggtcttg aaggcatcct cgaccagttc
     1141 caatttcacc aaccacttgt agcctgtacc cttattgggc ttgtaacagg tcacttggaa
     1201 gcagggatta tcctcggtgg atcgcttcaa atgattgccc ttggttggtc aaatatcggt
     1261 gctgctatcg ctcctgatgc tgcacttgct tctgtcgctg ctgccattat catggttctt
     1321 ggtggtgact ttaccaagac tggtatcggt gttgcccaag cggttgctat ccctcttgcc
     1381 gtagctggac ttttcttgac aatgattgtt cgtacaattt cagttggttt ggttcatact
     1441 gcagatgctg ccgctaaaaa aggtgacttc ggcgctgtgg agcgtgcgca tttcattgcg
     1501 ctactcttcc aaggacttcg tatcgcgctt cctgcagctc ttctccttat ggtaccaact
     1561 gaaactgtac aaagtatcct tagtgccatg ccagactggc tcaaagatgg tatggctatc
     1621 ggtggtggta tggtcgttgc cgttggttac gccatggtta tcaacatgat ggcaactcgt
     1681 gaagtatggc cattcttcgc tcttggtttc gttctcgctg ctgtgtcaga tattactcta
     1741 atcggattcg gtgctatcgg tgttgctatc gctcttatct accttcacct ttctaaaact
     1801 ggtggaaatg gtggcggagg agccgcaact tctaacgacc caatcggcga tatcctagaa
     1861 gactactaag ataagaaagg actgaaaaca tcatgactga aaaacttcaa ttaactaaat
     1921 cagatcgtaa aaaagtttgg tggcgttcaa ccttcttaca agggtcttgg aactttgaac
     1981 ggatgcaaaa cttgggctgg gcttatacac tcattccagc tatcaaaaaa ctctatacta
     2041 aaaaagaaga tcaaatcgct gctcttgagc gtcaccttga gttcttcaac actcatccat
     2101 acgtagctgc tccagtcatg ggggttactc ttgcgcttga agaagaacgt gctaacggtg
     2161 tggaaatcga tgacgctgct atccaagggg ttaaaatcgg tatgatggga cctcttgctg
     2221 gtatcggtga cccagtattc tggtttacag tacgcccaat ccttggatct ctcggtgctt
     2281 cacttgccct tactggcaat atcttggggc cactcctctt ctttgttgca tggaacttga
     2341 ttcgtatgtc attcttgtgg tatgttcaag agattggata caaggctgga tcagaaatca
     2401 ctaaagatat gtctggtggt atccttcaag atatcactaa aggagcttct atccttggga
     2461 tgttcattct tgctgtcctt gttcaacgtt gggtaaatat taaatttgct ttcgatgttt
     2521 ctaaagttca actagatgaa aaggcttata tccattggga taaattgcca gaagggtcta
     2581 aaggtatcca agaagcattc gcacaagtag gacaaggatt gtctcaaact cctgaaaaag
     2641 ttactacttt ccaacaaaac ttggatatgt tgattcctgg attatcagga ctactcctta
     2701 ctttactttg catgtactta cttaagaaaa aagtatctcc aatcactatt atccttgccc
     2761 tcttcgcagt gggtattgtg gcacatgttc ttcacatcat gtaatcaagc aactaaaaag
     2821 gaaccaggtt ctaaaatctg attccttttt tctatgcttt tattcagcca aggctcccat
     2881 tggatcccat ggtgcaagta cgattggttc tgctccatag gcagcttgtt cttctgctgt
     2941 cagcaattcc ttacgaacaa cgatttggta tgtgtattcg tccatccaag cgtctgaggc
     3001 aacaaagtaa ccatctgtac cgaccttgtc tccccatgag ttttcaacct tccacttggt
     3061 tgatttacca ttttcgtcca agtcaacacc tgtcaagacc atggcgtggg tcatcaagct
     3121 ttcgctatag tccaaacgtc cagccttgtc ttgagtaagt ttaatgtcca tgcttgattc
     3181 aaagtcataa acatctgtcg caaggatgcc agccttacgg ttgctgagct ggccgacatc
     3241 agaaccaaac caaacagtct cacctgcttg catttgggca atcgccaatt ctttcaagcg
     3301 ctccattgga acgttgatgt agcgaactgc acggctacca accacattcc ccaacatctc
     3361 aactgtgtaa gattttccgt aaggtttatc agcagttgga gcattgataa cagaaacgta
     3421 gtcttctaaa ggaagattga catatttctt gtaaaactct tgtggtgtga ttcctttttc
     3481 acttttatag ttgttatctt tatcgcgata agcaaagtca aacttgcgtg gtggaagtcc
     3541 taatgacata gcaagaaagt taaagatttc ttgcaagagg tcttctttct tagcttgaac
     3601 agtcgcttga tctgcaccag aaacaagcaa atcacgcaag atttgagcat cttgacgaag
     3661 caatttatta aggatcgcat ttagctcacg actgctgcta gatgaaacag actcaggata
     3721 aactgactta ggcacgacac cgtatttttc aaagagggaa acgaccatat cccattgacc
     3781 gccatcttgt tgaggtgttt ggagtaagaa gctaaccttg cggctagtca attcttggtc
     3841 tgaagtcgca atgacttgct ccaagaacca gtttgatttc tcatacttat cccagaagaa
     3901 agtgtgggct tgtgacaact caaagttctc caatttgtat tgcgagatga gtttgtggcg
     3961 gaaggtgttg agagccgcaa acatccagca acgaccagac gctttctggt tagtgacctt
     4021 gtccttggtt aaatccaatg agaaaacagg tgtgttgtct acatggcttt ggcgacattc
     4081 cagagctgca aaaattccgt tgtggctggc agcattttca atcgcttggt attttacatt
     4141 tgcttcatag ttggcaaata gtttatcagt aaatgattct tgaatcgcgt tcatagattc
     4201 ctccttttat tctacagtct attataactc ttttcacaaa ggaagcaact aaaaaacata
     4261 aaaggcgagg acattgtccc tcaccttttt cgaatttata ctcttcgaaa atctcttcaa
     4321 accacgtcaa cgtcgccttg ccgtactcaa gtacagcctg cggctagttt cctagtttgc
     4381 tctttgattt tcattgagta ttaaactaaa ttaaataata ttagcgcgga gaatttctaa
     4441 ttcttccttg gtcaagcgac gccattcccc tcgttccagg ttctcatcta atactaaagt
     4501 tcccatagtc aatcgttgca agtccaccac ttccttgcca cagtagccca ccatacgctt
     4561 gatctgatga aacttccctt ctgcaatggt cacacggatt tggctctgat tcttttctgc
     4621 atctgtggaa agaatctcca gtctagcggg ctgacaggta aagtctttga gcggaatgcc
     4681 cttgataaat gtctccacat cttcttgggt cataattccc ttgacctgag cctgataagt
     4741 cttgtccaca tgacgcttgg gcgaaagaag aacatgagcc agctgaccat tattggtcaa
     4801 gagcaaaaga ccatgcgtgt caatatccaa gcgtcctact ggaaaaactt ccttactccg
     4861 cgccaagtca tccaacaagt ccagaacggt tctgtgcttg ggatcctcag tcgctgagat
     4921 aactcctttg ggcttgttca tcatgtagta gacaaactct tcatactcca acacttgccc
     4981 atcaaagcga atctcatcta ttttttcatc aatctgcaat ttagctgatt tttctttttt
     5041 accatttaca gtcacgcgcc cagccttgag caagtttttg acctcagtcc gacttcccac
     5101 cgcacaggca actaaaaatt tatctaatct catagaacta ttatatcata tcaaaaggag
     5161 gctagtacaa tgaccaacct ccttttcgtt tcatactctt caaaaatctc ttcaaaccgc
     5221 gtcaacgtcg ccttgccgta tatatgttac tgacttcgtc agttctatct gcaacctcaa
     5281 aacagtgttt ttagctgact tcgtcagttc tatctgcaac ctcaaaacag tgtttttagc
     5341 tgacttcgtc agttctatct gcaacctcaa agcagtgctt tgagcaacct gcggctagtt
     5401 tcctagtttg ctctttgatt ttcattgagt atcagattta ggaaattaac ttcctcgtct
     5461 ccaaaaaata gctaaaacaa tcatggctcc taaaatcgct gggataatag ctgttcctga
     5521 taaaactggc ccccaagttc caaagagcaa gtgacctaga aaggctccga tccaaccgag
     5581 aaacattttt ccaaaacatc ccattcgctc tccacgattg gtcatagcac ctgctaaaaa
     5641 tcccactagg agaccaacga acatacttcc taacatatta tctccttaat ttgcccaatt
     5701 cccattacgg aaaagaggta cccgcgttcc atcctcacga ataccatcga tatccatttg
     5761 gttagaacca atcataaagt ctacgtgaac atctgaacgg ttaagccctg cagcttcaag
     5821 ctcctcttcg ctcatctccg ctccatcaac aacgctagtc gcataggctg caccgatagc
     5881 caagtggttt gacgcatttt catcgaaaag ggtgttaaaa aaggtaatgc ctgactgaga
     5941 aattggactt ggatctggta ccaaggcaca ttcacccaag gcacgcgcac ccgcattttt
     6001 aaagacaagg tctttcataa cctgatcacc cttctcagca gtgatatcta cgatttgtcc
     6061 atccttaaag gtcaccttaa tgccttcaat gatatttccg ttgtagctaa gcggttttgt
     6121 agaagtgaca taaccatctg cacgacggaa gtcaggcgct gtgaagacct cttctgtcgg
     6181 catatttggc aagaatcctt cgccctgtgc attgacagca ccagctgatt cccaaacgtg
     6241 gttctttggc aaaccaagtg ttaaatctgt tcctggcgct gtgtagtgaa gggctgaaaa
     6301 ttgctcctta ttaagcatat cggccttgct cttcaagata gctgcatgct cttcccaggc
     6361 cttaacagga tctgcttcgt agacacggca agttttgaaa atttggtccc aaaggaaatc
     6421 aactgcttct tcgtcgctcg cagcatttgg gaagactttc ttagcccact caagtcctgc
     6481 tgcagctgct acagtccagc taaccttgtt agattgagtt gcgatacgca taggcttcat
     6541 ggcaagtccc atagctttag cagaagctga aagcttgtca gcgtccactc cgttcaaggc
     6601 acctggatca gatgaacgaa ctccaagacg gctagcctta ttctccaaga gatagttcat
     6661 ctcagcaatc ttgtattctg gcacattgtc caaactctcc atcggggcat ggagaaattt
     6721 ctcacggtta atcacatcat ctgtccactg aacgatgacc tcatgcgcac ccaaggcata
     6781 agcttctttc acgattagat gtgccaattc acgttgctcc acatcaatag agagagccaa
     6841 agtgtgacca ggttgcacgt taattccgtt cgcaaccaac aatttcgcat atttttctag
     6901 attttcttta aaatttggta aaaccatgta attttctctt ttctattttt atttttcttt
     6961 caaagcagag aataatcacg ctaaagcaat agcacctgac aagagtgctg ttgatagaag
     7021 aattgtacga tcagcaagtt ctaattgata ttcaaatacc ttcttagccg gcttatcttc
     7081 cgcaaatatt cttagtttca tgagaacccc cttaaaatag attaaaataa atcactgtga
     7141 ctgcctgtcc tcagcaaatt taaaatcaat tccgacttgt ctactttata aaccaaaagc
     7201 caatctggct gggtatggca ttcacgaact ccttgaaaat gcttggatgc cgtcaatgaa
     7261 tgatcacgat atctggtagg atgttctttt tcttgaacca gaaaattcaa aacttcttct
     7321 aataattctg ccttcaaacc acgcttcata gccaacttaa aatctttttt aaactgttta
     7381 tgatagcgaa tcttaagcac gtaagtcctc catcaaatct gagactgatt caaaagactg
     7441 gctcatatta cgattttagt ctaaatccgt taacgcttgg agcaacttcc gattttcgtc
     7501 tagtctaaca tcaaaaggta atccctgata ttgaattgcc tgacgaagga aaatattaat
     7561 agctgttgtc atatccattc ccagattact aaacacctgt tgggcctgct ccttaacctc
     7621 actatccaga cggatgctta tactcatctt tgacatactc tcaccctctt tccatagact
     7681 attttaacaa aaaagaaagc taatgtaaat ctattggata tacgttagcc tcttttaata
     7741 gattattaag caatttttta aaacaactca tcaaacaaac tcaactggtt atcctctggc
     7801 atatttccaa gaatacccat ctcatccatc ttttcaacca aggttgatga gagtccacca
     7861 cgcttgcgta gttctgtttt agagaggaat tctccctctt cacgcgcccg caccagttgc
     7921 ttggcaacgt tctctcccag accatccatt gctacaaatg gtgggataag ggtatccccg
     7981 tcgatgagga actctgtcgc ctgactacag tagagatcta atttaccaaa cttgaaacct
     8041 cgttcccaca tctcattgac aatctcaaga gttgtataga gatcgatttc cacattagag
     8101 gcttcattgt tcttccgttt ttcagagatt tcttccattc tgcgcttgat ggcctccaag
     8161 cccgcaccca tggtcttgat atcaaaagcc ttagcacgaa tggagaagta agcacagtag
     8221 taataaatag gatggtgaac cttgaagtaa gctacacgca aggccatcat aacgtaggct
     8281 gccgcatggg ccttagggaa catgtactta attttcccac aggattcgat ataccactct
     8341 ggcaccttat tagccttcat ggcttcgata tagccatttc tctcctcttc tgaaatcttt
     8401 agccacaaac ccttacgtac ccgttccata atggtaaagg ccatcttagg ttccagaccc
     8461 gcatgcatga ggtaaaccat gatgtcgtcc cgacaaccga taacagtcga taggtccgct
     8521 attccttgct taatcagatc ctgagcattc cccaaccaaa cgtcagtacc gtgggacaga
     8581 ccagacagct gaagcaattc cgcaaaggtt gtcggatggg tttcgtctac cattccacgt
     8641 acgaaatttg ttccaaactc tggaatcccc aacatacccg taggcgttcc aatttgttca
     8701 ggtgttaccc ctagcacatc agtcccagaa aagagtgcca tcacgccttc gtcatccata
     8761 ggaattttat tagggtcaat accagacaaa tcctgaagtt ttcgaatcat ggtcggatca
     8821 tcatgtccca gtacatcgag tttgaggacg ttctcatcga tatcgtggaa gttaaagtga
     8881 gtggtctgcc attcagccgt gacatcatct gctggatact ggacaggcgt aaaatcgtag
     8941 acatccatgt agttcggaat aacaacgatt ccccccgggt gttggcctgt tgtccgcttg
     9001 acacccgccg ctccttgagc gaggcgttct acttctgcat cacgataaaa cttgccataa
     9061 tctcgctcgt aacccttgac aaatccatag gcagtcttgg cagctactgt accaaccgtt
     9121 cccgcacgga aggcatattc ttcaccaaag atatcacgca catccaagtg ggcgctaggc
     9181 tgatcttctc ccgagaagtt caagtcaata tcaggaacct tatccccatc aaaaccaagg
     9241 aaggtctcaa acggaatatc ctgtccgttt ttactgagtt tgtgaccaca gtttggacag
     9301 tccttatggg gcatatcaaa tcctgaaccg tacgaaccat ctgtgataaa ctcactgtac
     9361 tgacactgac cacagacata gtgaggagag agaggattga cctccgtaat cccaatcatg
     9421 gtcgcaacga aactagatcc gacagaccca cgagaaccaa ccaaataacc ccgttcatta
     9481 gaacgttgca ccagcatctg cgatgccaaa taaatcacag caaatccatt ccccagtatg
     9541 gatgttaatt ctttttcaat ccgcaaatca acaatatctg gcagcggatt cccataaatc
     9601 tcaaaagctt tcttataggt caactcagca actgtttctt cagccttgtc gatgaaaggc
     9661 gtatacaagt cacccttaac gacttcaacg ggttcaaata tttctgccaa ggcattggtg
     9721 ttttcaataa ccagtttacg agccagttcc tctcccaaaa aggcaaattc atccaacatc
     9781 tcattagtcg ttcgaaaatg agcctttgga agtggcgctg gttgggcatg ttcaccatga
     9841 ccgatagttc ggttaatcat cgcaccctgt cccaaactac ggacgataat ttcacgataa
     9901 acctcttctt ccggttcgat atagtgaaca tttcccgtag ccagaacagg cttgccaagg
     9961 cgatctccaa cctctatcaa actcttgata atggtctgga gttcctccat atccttgacc
    10021 tgctctttgg caatcaaggg cgcatagata gccggtggca tgacctcgat aaagtcataa
    10081 tacttggcca cctcaaccgc cgcatccaca ccttgagaaa cgaccacgtc aaaaacttca
    10141 ccctctgaac aggctgaacc taaaatcaag ccctctcgat gggcatctag aaccgttctc
    10201 ggaatccgtg gcactccttc aaaatacttg gtattagaca aggaaaccag cttaaagata
    10261 ttttttagac ctacctgatt cttgacatag atggtcgcat gcttgatccg agcttttttg
    10321 taagaatctg gactgattag atcaatgttg agtctatcta aatcggtcac accatgtttt
    10381 tctgctacct ctttgataaa gatgaaaagc agacgaccag tcgcttccgc atcgtagttg
    10441 gccatgtggt gatgttccaa ggccacacca aaacgcttgg tcaaaggccc caaaccatgg
    10501 cgtttatact caggatagag gtttctagca aactccagcg tatcaataac tggctgacta
    10561 atctttggaa gatcatgacg ctcataatta gcattcataa agccaacgtc aaaggtagca
    10621 ttgtgggcaa ctaggaccgt atccttgcaa aattcttgga attcttgcaa aacttgttct
    10681 agtggtttgg catttttgac atgatcatct gtaattccag ttaactctgt agtaaaagct
    10741 gacaagggat gcccaggatt gataaattca tcaaattcag caataacatt ccccttgtac
    10801 atcttagagg ccgcaacctg aatcaagtca ttatagatag ctgaaagtcc cgtcgtttcc
    10861 acgtcaaaga ccacgtaggt tgcttctgac aagtccatct ccacttcgtt atagacgata
    10921 gggacacggt cctccacgat attggcttcc attccataga tcagctggat tcccgctttc
    10981 ttagccgcct tatagccatg tggaaaggac tggacattcc catggtccgt gatagcaacc
    11041 gccttgtgtc cccacttagc agctgttgca acaatctctt cgacctctgg caaagcatcc
    11101 atagtcgaca tgttagtatg agcatgaaac tcaacccgac gctcaccttc tggcatcaaa
    11161 tccttccgct catagtgaac aacttcctgc agatcctgta cgttcatagt caaatcgcgt
    11221 gtgaagttat tcatctccac attccctcga actcggagcc aagaattctt cttgatgagg
    11281 tcaaacttct gggcctcttc ctcgttttta acccactttt gcatagaaaa acttgaagta
    11341 tagtccgtca ttttaaagtt gattaaaaca cgacctgttc tagtcacttt ttgctccaca
    11401 ttaaaaacaa ccccttcaaa taccagacga ttttcctctg tcgtcacttc gatcatagga
    11461 gtaatctccg ccttatccag cttgggttta gctgcagctt ttttcgcttg aaaatcaaag
    11521 actggtttct cttccgctgg aggaggtgcc atctgctcca gttgttccat agcacggagc
    11581 gcttcctcat tggcagcttg aacaatctgc tcattttcag catgaaaggc ctcttcctgc
    11641 tcttgggtca ggacatcatt cttctcgact tgacagttaa aagttggaaa accaaacttt
    11701 tcaagttgtt tggctaaatt aggaagatga ttcttcttaa aatgttcctt atcaatcgct
    11761 tcagatcctt caataaatag ctgattaccc tcagcacgaa cttgcaaatt ttgataaagg
    11821 gacttaaaac cttgactagc acatggacct tcagagaaag cctccctata gtaggactgc
    11881 aagagctgat ttgaaaattc ttgagaccga gccttaattt caaaaacagc tttattgcct
    11941 gtcttagaaa attcttcgct caaacctttc tttaattcta aaaagatttc aatcggtaaa
    12001 atattagaaa atacgaaatg aaactcccat accttactaa ttttatgaac cacaactcgc
    12061 tcaatattag cctgtgctaa agcaggagcc tgtctcattt cagcaggcat ccccaattga
    12121 ttcatcaaaa tttcaaaact atttgacatt cattttcctc acattattct tctactattt
    12181 taccatattt agaggtattt tctaaagaca aaaggaagcc actaagtgac ttccttctag
    12241 agtgaggacg gattagtctt cacctttatt tttcttaata atttcttctt gtactgactt
    12301 aggtacatct tcgtagtggt caaataccat catgaatgta ccacgtcctt gagatgcaga
    12361 acgaagaact gttgcgtaac cgaacatttc agcaagtgga acgtaagcac gaacgatttg
    12421 gctgttaccg tgtgcttcca taccatctac acgtccacga cgagcagtta cgtgacccat
    12481 aacatcacca aggttttctt ctggaacagt gattgttaca agcatcattg gttcaaggat
    12541 agctggttgt gctgatttag cagcttcttt aagggaaagt gaagccgcaa tcttgaaggc
    12601 agtttcagat gagtcgacat cgtgatatga accatcataa agcttagctt taacgtcaac
    12661 cattgggtaa cctgcaagaa caccgttagc catagattct accaaacctt tttcaaccgc
    12721 tgggataaat tcacgaggaa ccacaccacc gacgattgcg ttttcgaatt cgaatccttt
    12781 accttcttcg tttggagtaa attcaatcca cacatcaccg aattgacctt taccaccaga
    12841 ctgacgtttg aagaatccac gtgcttgagt agaagcgcgg aatgtttcac ggtaagatac
    12901 ttgaggagca cctacgttcg cttcaacttt gaactcacga cgcatacgat caacaaggac
    12961 gtcaaggtga agttcaccca tacctgagat aactgtttca ccagtttcaa cgtttgtttc
    13021 aacgcggaat gttggatctt cttcagccaa tttttgaagg gcgataccca tcttgtcttg
    13081 gtcagcttta gattttggct caaccatcaa ttggataact ggttctggaa cgttgattga
    13141 ctcaaggatg attttagctt tttcatctgt caatgagtca ccagttgtag tatctttcaa
    13201 accaacggca gcagcgatat cacctgagta aacagtgtcg atttcttgac ggctgttagc
    13261 gtgcatttga aggatacgtc cgatacgttc acgtttacct ttagaagtat tcaatacgta
    13321 tgaacctgat tgaagaacac ctgagtaaac acggaagaat gtcaaacgac ctacgaatgg
    13381 gtcagtcatg atcttgaagg caagagctgc aaatggctct tcgtcagatg ctggacgaat
    13441 ttcttcagcg tctgtatctg ggttaatacc tttgattgct gggatgtcaa gtgggcttgg
    13501 aaggtagtcg ataaccgcat caagcatcaa ttgaacacct ttgtttttga aggctgaacc
    13561 acacaatact gggaagaatt caacgttgat agtcgcttta cggataccag ctttcaattc
    13621 ttcgttagtg atttcttcac cttcgaggta tttcatcatc aattcttcgt cagtttcagc
    13681 aactgcttca atcaattttt cacggtattc ttgagcttgg tcaaggtatt cagctgggat
    13741 gtcttcttca aggatatccg taccaaggtc gttagtatag atttcagctt tcatcttgat
    13801 caagtcaatg ataccacgga agtcatcttc agaaccgatt ggcaattgga ttgggtgtgc
    13861 atttgcttga agacgatcgt gaagtgtgct tacagagtaa aggaagtcag caccgatttt
    13921 gtccattttg ttggcaaata cgatacgtgg aactccgtac tcagtcgctt gacgccaaac
    13981 tgtttcagtt tgaggctcaa cacctgattg tgagtcaaga acggtaaccg caccatccaa
    14041 tacacgaaga gaacgttgta cttcgattgt gaagtccacg tgtcctggtg tgtcgatgat
    14101 gtttacgcgg tggttgttcc attgagctgt tgtcgcagca gatgtgatcg tgataccacg
    14161 ttcttgctct tgctccatcc agtccatttg tgacgcacct tcgtgagttt caccgatttt
    14221 gtggatttta ccagtgtagt aaagaatacg ctcagtagtt gttgttttac cggcatcgac
    14281 gtgagccatg ataccgatat tacgagtttt ttcaagtgaa aattcgcgtg ccatgaggtt
    14341 tgtttctcct atttattttt gatttctatt ctattataac acgattttaa taaaaacgga
    14401 taggcaggac ctacccgttc tcaatgtttt catgctattg ttggtttcaa cttacgagat
    14461 ggtaagctga gttatagcta atactaatcg atttagctaa tttgaacccg ggctaaagtt
    14521 agttagccga tatgagctgg aacgggatgc tgcgtgaaaa agataaaact ccttgtattc
    14581 atcgaatact gcgtcagttt cctattttca ccttgcatcc ttaccgttcc tagcatcatg
    14641 atttagttga gctcaagcta aaagtctgga gaaaaagatg aatctcattg gttgcaaccg
    14701 caacctgctt cgattcccta ttttctctgg gactttctta acgctttcgc atcctatctt
    14761 accaacggaa gtgtgcgaat gcacggttag cttcagccat acggtgagta tcttcacgtt
    14821 tcttaactgc tgcaccagtg ttgttagcag catccaagat ttcttttgca agacggtctt
    14881 gcattgtgtg ttcaccacga agacgagcga ttgttaccaa ccaacgaagt ccaagtgttg
    14941 tacgacgttc tggacgaact tcaactggga cttggtagtt agaaccacca acacgacgtg
    15001 cacgtacttc aagtacaggc atgatgtttt ccatagctgt ttcaaatact tcaagtgcat
    15061 cgttgccagt agcttctttg atttgctcaa aagcaccgta aacgattgaa gcagcagtac
    15121 cacgtttacc atcaagcata acgcggttga taagacgagt aactagttgt gaattgtata
    15181 gcggatctgg caatacgtca cgttttggag ctctattttt acgactcatt tctctttatc
    15241 ccctttcctt atgcttttgg acgtttagta ccgtatttag aacggccttg tttacgatcg
    15301 ttaacacctg cagtatcaag tgcaccacgg acgatatggt aacgtacccc tggaaggtct
    15361 tttacacgtc caccgcgaag aagcaccacg ctgtgctctt gcaagttgtg tccgatacct
    15421 gggatgtagg cagtaacttc gataaggttg ctcaaacgta cacgagcgaa tttacgaagg
    15481 gctgagttag gttttttagg tgtcattgtt ccaacacgag ttgcaacacc acgtttttgt
    15541 ggtgaagaaa cgtttgtttg aactttttta tgactattgt aaccaacgtt caaagctggt
    15601 gatttagatt tttctacttt tgatttacgc ggtttgcgaa ccaattggtt aattgtaggc
    15661 atctacattc tcctgtgttt ttttattttt ggtgatgata cacttggtga cagatatcat
    15721 ctgtgtgtac ttttgcaaca tttgtcagca cgtccctgta cactcttgag agaccaaaag
    15781 taaaaagtac cgtctattat tgtaacaaaa ttttcccttg cttgtcaaga tatttttctt
    15841 ttttattggt aatgttagag atcaatttct gaataaaaat agctgagaac acatcatctt
    15901 cctaataaca cggcttggct tacgtgacat ttttatctcc gtcatttata ctgatatata
    15961 aaatagtacg gaaaacttct caaaagtaag aatttctttc acaaatcaaa gaaaacgctt
    16021 gcatattgtt ttactacatg ctatactgat atagaaattt attgattgga gaatcattat
    16081 gagaaaaaca ccatctcaca ctgagaaaaa aatggtctac agcatccgtt ccctcaaaaa
    16141 tggaactggt tctgtcctta tcggcgcaag ccttgtcttg cttgccatgg ctacaccaac
    16201 tatctcatcc gacgaaagta caccaaccac taacgaaccc aacaacagaa atacaaccac
    16261 ccttgcccaa cctcttactg atacagcagc tggctctggt aagaacgaaa gtgatatttc
    16321 ttcacctgga aatgcaaacg cttccctaga gaaaacagaa gaaaaacctg ctgcaagccc
    16381 agccgatcca gcaccacaaa ctggacaaga tcgttcaagt gagccaacta cttctactag
    16441 tccagtaaca actgaaacta aggcagaaga gcccatcgaa gataactact tccgtatcca
    16501 tgtcaaaaaa cttcctgaag aaaacaagga tgctcaagga ctatggactt gggacgatgt
    16561 tgaaaaacca tctgaaaact ggccaaacgg agctttgtcc ttcaaggatg ccaagaaaga
    16621 tgactacggc tattacctag atgtcaaatt aaagggagaa caagccaaga aaattagctt
    16681 cctcatcaac aatacagctg gaaaaaatct aaccggcgat aaatctgtag aaaaactagt
    16741 tccaaaaatg aacgaagctt ggttagacca agattacaag gttttctctt acgagccaca
    16801 gcctgcagga actgttcgcg tcaactacta ccgcacagat ggcaactatg acaagaaatc
    16861 tctctggtac tggggagatg tgaaaaatcc aagtagcgct caatggcctg acggaacaga
    16921 ctttacggct acaggcaaat atggccgcta tatcgacatt cctcttaatg aagccgcaag
    16981 agaatttgga tttttattac tagatgagag caaacaagga gacgacgtga aaatccgtaa
    17041 agaaaattat aagttcacag atttgaaaaa tcatagccaa attttcctaa aagacgatga
    17101 tgaatcgatt tacacaaatc catactatgt ccatgatatc cgtatgacag gagcccaaca
    17161 cgtaggcact tctagcattg aaagtagctt ttcaacactt gtcggtgcta aaaaagaaga
    17221 tatcctcaaa cactccaaca tcactaatca cctaggaaac aaggtaacta ttaccgatgt
    17281 tgcaatcgat gaagctggta agaaagtgac ctacagcgga gatttctctg acacaaaaca
    17341 tccttatact gttagctaca attccgacca attcactacc aaaacaagct ggcgcctgaa
    17401 agatgagaca tacagctatg atggcaaact gggagctgac ctaaaagaag aaggaaaaca
    17461 agttgatttg accctttggt caccaagtgc tgataaggtt tctgttgttg tctacgacaa
    17521 gaatgaccct gacaaagtag ttggaactgt cgctcttgaa aaaggggaaa gaggaacttg
    17581 gaaacaaact ctagacagca caaacaaact cggaatcaca gatttcactg gctactatta
    17641 tcaataccaa atcgagcgtc aaggtaaaac tgttcttgca ctcgatcctt acgctaaatc
    17701 tcttgctgct tggaatagcg acgattccaa gattgacgat gcccataaag tggctaaagc
    17761 cgcctttgta gatccagcta aactcggacc tcaagacttg acttatggta agattcacaa
    17821 tttcaagact cgtgaagacg ccgttatcta cgaagctcat gtgcgtgatt tcacttcaga
    17881 tcctgccatt gcaaaagact tgaccaaacc atttgggact tttgaagcct tcattgaaaa
    17941 actagactat ctcaaagact tgggtgtaac ccatatccag ctccttccag tcttgtctta
    18001 ctactttgtc aatgaattga aaaaccatga acgcttgtct gactacgctt caagcaacag
    18061 caactacaac tggggatatg accctcaaaa ctacttctcc ttgactggta tgtactcaag
    18121 cgatcctaag aatccagaaa aacgaatcgc agaatttaaa aacctcatca acgaaatcca
    18181 caaacgtggt atgggagcta tcctagatgt cgtttataac cacacagcca aagtcgatct
    18241 ctttgaagat ttggaaccaa actactacca ctttatggat gccgatggca cacctcgaac
    18301 tagctttggt ggtggacgct tggggacaac ccaccatatg accaaacggc tcctaattga
    18361 ctctatcaaa tacctagttg atacctacaa agtggatggc ttccgtttcg atatgatggg
    18421 agaccatgac gccgcttcta tcgaagaagc ttacaaggct gcacgcgccc tcaatccaaa
    18481 cctcatcatg cttggtgaag gttggagaac ctatgccggt gatgaaaaca tgcctactaa
    18541 agctgctgac caagattgga tgaaacatac cgatactgtc gctgtctttt cagatgacat
    18601 ccgtaacaac ctcaaatctg gttatccaaa cgaaggtcaa cctgccttta tcacaggtgg
    18661 caagcgtgat gtcaacacca tctttaaaaa tctcattgct caaccaacta actttgaagc
    18721 tgacagccct ggagatgtca tccaatacat cgcagcccat gataacttga ccctctttga
    18781 catcattgcc cagtctatca aaaaagaccc aagcaaggct gagaactatg ctgaaatcca
    18841 ccgtcgttta cgacttggaa atctcatggt cttgacagct caaggaactc catttatcca
    18901 ctccggtcag gaatatggac gtactaaaca attccgtgac ccagcctaca agactccagt
    18961 agcagaggat aaggttccaa acaaatctca cttgttgcgt gataaggacg gcaacccatt
    19021 tgactatcct tacttcatcc atgactctta cgattctagt gatgcagtca acaagtttga
    19081 ctggactaag gctacagatg gtaaagctta tcctgaaaat gtcaagagcc gtgactatat
    19141 gaaaggtttg attgcccttc gtcaatctac agatgccttc cgacttaaga gtcttcaaga
    19201 tatcaaagac cgtgtccacc tcatcactgt cccaggccaa aatggtgtgg aaaaagagga
    19261 tgtagtgatt ggctatcaaa tcactgctcc aaacggcgat atctacgcag tctttgtcaa
    19321 tgcggatgaa aaagctcgcg aatttaattt gggaactgcc tttgcacatc taagaaatgc
    19381 ggaagttttg gcagatgaaa accaagcagg atcagtcgga attgccaacc cgaaaggact
    19441 tgaatggact gaaaaaggct tgaaattgaa tgcccttaca gctactgttc ttcgagtctc
    19501 tcaaaatgga actagccatg agtcaactgc agaagagaaa ccagactcaa ccccttccaa
    19561 gcctgaacat caaaatgaag cttctcaccc tgaacatcaa gatccagctc cagaagctag
    19621 acctgattct actaaaccag ataccaaagt agctgatgcg gaaaataaac ctagccaagc
    19681 tacagctgat tcacaagctg aacaaccagc acaagaagca caagcatcat ctgtaaaaga
    19741 agcggttcga aacgaatcgg tagaaaactc tagcaagaaa aatatacctg caaccccaga
    19801 tagacaagct gaacttccaa atacaggaat taaaaacgaa aacaaactcc tatttgcagg
    19861 aatcagcctc cttgcgctcc ttggtctcgg tttcttacta aaaaataaaa aagagaacta
    19921 aactagccct cctatagaaa aatcccccaa gcattatagc tcgggggatt aattttcgta
    19981 caatatttgt tgtcctaata aacttgatta ggatttttta ttaagcctct ttcatagcaa
    20041 aataagctcg tactttgggt gcaacttgtg ttccgaagag ttcaatagct ctcagaacct
    20101 ggtcatgagg catagaacca agcggtagat gaagcatgaa gcggtccaat cctaaatcct
    20161 ctatcatgcg aatcaatttt tcggccacct gatctggatt gccaacaaac atggcgccat
    20221 ttgaccctac ctgctccaaa tattgctcat aacgcaattc ctgccagtgc ggacggtctt
    20281 tggaaatagc atccaccact tgcttagtcg gatggaaata atctttcacc gcctgctcac
    20341 catcttccgc aatccacccc caagaatggg ctcccacttt caagtctttg tcagcatgga
    20401 ccgcttcgct tccaatctca cgataagcct gaatcaactt tttaaaataa cgtggattac
    20461 caccaataat agcatataca atcggtagac cagcctgagc aatcttcact gttgattcga
    20521 catgaccacc tgtagctatc cacaagggca atttgtcctg aactggacga ggataaactt
    20581 ctttaccagc aatcgtttga gtcaatcgac cttgccagtc taacttggtc ttttcattga
    20641 ctaactgaag caagtctaat ttctcatcaa aaagagagtc gtagtctttc aagtcataac
    20701 caaacagagg gaaagattcc gtgaaagagc cccttccagc cataatctcc gctcgtccat
    20761 ttgacaaagc atcgatagtg gcatactgtt ggaacaaacg aatcggatcc atgcttgaca
    20821 gaatgctgac tgcactggtc aaacggattt tcttggtatt gactgcccca gcggccagga
    20881 caatctctgg ggctgatact gcaaaatccg cccgatggtg ctcgccaatc ccatatacgt
    20941 ccaaaccaac cttgtcagcc agctcaatct ctgccaccaa ctggcgaatg cgttcagcat
    21001 gactgtaagt ttgtccagtc ccttcaagct ccgttatttc cccaaatgtt gaaattccca
    21061 attctaccat tgtgattctc cttgtctatc tctgtccttc aatttgaaaa attattctaa
    21121 cactcaatga aaatcaaaga gcaaactagg aagctagccg caggttgctc aaaacagtgt
    21181 tttgaggttg tggatagaac tgacgaaatc agtaaccata cctacggcaa ggcgacgttg
    21241 acgtggtttg aagagatttt ctaagagtat aacacgaatc ttgagtacaa gcaaccaatt
    21301 tgctcacaag aaaaagccta gataactaga cttttttagc ttattctacc gttactgact
    21361 tggcaaggtt acgtggtttg tccacatcga ggccacggtg gagggttgca aagtaagcga
    21421 ctaattgcgt tggtacgacc attgaaattg gtgagaggta tggatgtacg gtcgtaagga
    21481 cgatatcgtc ggtatctttg gctacattct cttctgcgat agtgaggact ttggcaccac
    21541 gggctgcgac ctcttggata tttccacgag tatggttggc aagaactgga tctgacaaga
    21601 gagccaaaac aggcgttcct tcttcaatca aggcaatggt tccgtgcttg agttctcctg
    21661 ccgcaaaacc ttcacactgg atataagaaa tctctttgag tttgagactt gcttccatgg
    21721 ctacgtaata atcttgacca cgtccgatgt aaaaggcgtt acgagttgtt tcaagaagtt
    21781 cacgaacctt ggcttcaatg gtttctttct ctgaaagagt tgattcaata gactgagcta
    21841 cgattgacaa ttcatgaacc aggtcaaagg cttgcgcttt agcattacca tttgcttctc
    21901 cgactgcttt tgcaaggaag gcaagggctg cgatttgcgc tgtataggct ttagttgatg
    21961 ccacggcaat ttcaggacct gcgtgaagga gcatggtata gttggcttca cgtgagaggg
    22021 ttgaacctgg aacatttgtc actgttaagc ttggaattcc catttcatta gccttgacca
    22081 aaacttgacg actatccgct gtttcaccag attggctgat aaagatgaag agtggtttct
    22141 tgctgagaag tggcataccg tagccccact cagatgagat tccaagttca actggtgtat
    22201 ctgtcaattc ttccaacatc ttcttagaag caaatcctgc atggtaagat gttccagctg
    22261 caaggatgta gatgcggtct gcgtcttgaa cagccttaat gatatctggg tctacgacaa
    22321 cttgaccagc ctcatctgtg taggcttgga tgagtttccg cataacagtt ggttgctcgt
    22381 caatttcctt gagcatgtag taagggtaag ttcccttacc gatatctgac aagtcaagtt
    22441 cagcagtgta gctagcacgc tcacgacgat ttccatcata gtcttgaact tccacgctat
    22501 cagccttgac gattaccaac tcttggtcat gaatttccat gtattggttg gtttcacgaa
    22561 tcatagccat agcatctgag cagaccatat tgtagccttc cccaagacca atcaaaagtg
    22621 gagatttgtt tttcgctaca tagatgacat ctggattttc agagtcaatc aaggcaaagg
    22681 catatgaacc acggataata tgaagagctt ttttaaaggc ttcaagaact gagagaccgt
    22741 cttcttccgc aaattttcca atcaaatgta cggcgatttc cgtatctgtt tgccctttga
    22801 agtggtgccc agcaaggtat tcttctttaa tttcaaggta gttttcaatc accccattgt
    22861 gaaccaagac aaaacgttct gtctcagagc ggtgtgggtg agcattgtct tccgttggtt
    22921 tcccatgagt tgcccaacga gtatgtccga taccagttgt tccctcaaca ccagctgtct
    22981 tggcagacaa ttctgcgata cgaccaacag ccttcaccaa atggttatca gcaccatcta
    23041 ggacaaaaat tcccgcagaa tcatagccac ggtattcaag cttttcaagc ccttgaatca
    23101 aaatatcagt tgcatttgtg tttccaacaa caccaacaat tccacacata gtatatacga
    23161 cacaggcaag ctgtgctttc tccttaaaat tggtatagtc taattcatct tttatagaat
    23221 cagcaaaaac agtatatact tgtttctttc acttgtcaag agtaaaaatt ggtatagttc
    23281 aaattaagct cctgtaagca aaaaactctg accgattggg ataatcagtc agagtccttt
    23341 ttaaaatcca ttattatcgc ttaatttttt gaaccagtgg cctgatttct tcagacgacg
    23401 ttcttgcgtt tccaagtcta attcgaccaa accatagcga tttttatagc tgttgagcca
    23461 tgaccagcag tcaataaagg tccaaatcaa gtagccctta cagttggcac catcttcaat
    23521 ggcacggtga agttcacgaa gatgaccttt tacaaagtca atacggtaat catcttgaat
    23581 cattccatct tgacggaatt tttcttcccc ttcaacaccc ataccattct cagtcaacat
    23641 ccattcaata ttgccataat tttccttgat attttgggcg atgtcataaa tcccttgctc
    23701 ataaatctcc caaccacggt gagaattgat tttacgtcca ggcatcacat aaggctcgta
    23761 aaaatgttct ggtaagagtg gactctctgg atgcttagca aatcgaggag ccataacacg
    23821 caaaggttga tagtagttca caccaaggaa gtccaccgta ttatcatgaa tgagttccaa
    23881 ctcttcctct gtagcatcag gtaaaagacc gtgttcatgc aagatttcta ccaactcctg
    23941 tggataagtc cccaagacag atggatctaa gaaagattgg gcctgaaaaa gggccgcaat
    24001 acgagctgcc ttgacatcag caggatgctg gctacgtgga taagccggtg tcaagttgag
    24061 gacaatccca atcttggaat caggcaaaag ttcatggcaa gccttaacag cccggctgct
    24121 ggccaattgt gtatgatagg ctaccttaac agctgcctct gcatccacct tatgtggata
    24181 atgggcatca taaaaataac caaattctac aggaacgatg ggctcgttaa aggtaatcca
    24241 ttgatccact aaatctccat aagtctcaaa acaaaaacga gcatagtctt cataggctga
    24301 gactgtcgcc ttattttccc aaccatcacc atcctcttga agggcaaaag gtaaatcaaa
    24361 atgatagaga ttgactaaca gacgaattcc tttagcctta atagcctcaa agaccttacg
    24421 ataaaaatcc acaccttgag ggttgacttt tccacagcct tgtggaaaaa tccgtgacca
    24481 ctgaatagaa gtccgaaaga ctgtgtgacc agtctctaac aaaagctcaa tatcccgctc
    24541 ccaattttca taaaaagtcg atgtcttatc tgaaccaatc ccattatagt aacgatttgg
    24601 ctccacttgg aaccagtaat cccagagatt gtctccctta ccgtcaccag ctacacgtcc
    24661 ttctgtctgc ggtccagaag tagaggatcc ccagacaaaa tcctttggaa atcttagcat
    24721 aacatttacc tctttatcta ctcatttctc ccattataca gaaaaaacaa ggtaaaaact
    24781 agttacattt tttccttgtt tttcttctga ttatagtttt tatttcttgc ttaggatttc
    24841 aagcgtttca agcacgttat ctgcatgaac ctcaatggtg tcaccagttg ccttgatctt
    24901 aacttctaca atgccatcgg ccgctttttt accaacagtg atacggattg gaagaccaat
    24961 caagtcacta tcgctaaatt taacaccgac acgttcgtta cggtcatctg tcaagacttc
    25021 ataaccagct cccatcaagc ttgcttcaag tttttctgtc aaggcttgcg cttcttcatc
    25081 cttgacattg acagtaatca aatgcacatc aaatggtgcc aattctttag ggaaattgat
    25141 tccccaagcg taacggtatt caccttttgg cgttttgtta acaaagaggc gagcgtgttg
    25201 ctccatcact gctgaaagaa gacggctgac accgataccg taacatccca tgatgattgg
    25261 cacagcacga ccattttcat ccaagacatc tgctcccatg cttgctgagt agcgagttcc
    25321 gagtttgaaa atatgaccga tctcaatacc acgcgcaaag ttaaggacac cttgtccatc
    25381 tggggaaatt tcaccctcac gaacttcacg gatatccaca tattctgcag taaaatcacg
    25441 gcctgggttc acaccagtca agtggtagcc atcttcgtta gcaccgacaa ctgcattgcg
    25501 aacatcttgc accttacgat ctgcaataat tttaatattc tctggcaaac caactggtcc
    25561 aagtgaacca aatcctgctt gaacaacatt cgccacttct tcttcgctag caacgtcaaa
    25621 gaaatctgct cctaagtggt ttttcaactt gacttcgttg agttggtcat ttccaactag
    25681 aagggctgca acaagctcac catctgcaat gtagaagagg gttttaatcg tttgttcttc
    25741 tggaacattg aggaaagctg caacttcatc aattgattta acatctggcg ttgcaacacg
    25801 agtaacttct tcttcagcga caacacggtt gcttggtttg tactcgtttg ttgccatttc
    25861 taagttagct gcatagctag actcacttga gtaagcaatg gtatcttcac cagagactat
    25921 ccatttgagc aattctgcct tgatttcttc ttgcacttct gcaggaattt cgtcaaatga
    25981 ggcaactgac ttgtccaaga caacccagcg gtcaaggtct gtacgagcag atgtaatggc
    26041 cataaattct tggctatcct taccacccat ggctccaccg tcaccaataa tagccttgaa
    26101 gtctaaacca ctacgagtga aaatacgctc ataggctgct ttgtactcat cataaacact
    26161 atccaaacta tcatagttag cgtggaaact ataagcatcc ttcatgataa actcacgtgt
    26221 acgaagaagt ccattacgtg ggcgtttttc atcacgatac ttgggctgaa tttgataaag
    26281 gttgagtggc aattgcttgt aagatttaac agaatcacgg acaatagctg taaaggtttc
    26341 ttcgtgagtt ggacctaaga taaagtctga tttttcacgg ttttttagtt tgtaaaggtc
    26401 ttcaccatag gtttcgtaac gacctgattc acgccacaat tctgcactaa gaagggctgg
    26461 agccaacatc tcaacagcac caatcttttc gaattcttgg cgcatgatgt ttttagcttt
    26521 ttcaatcaca cgattggcaa gtggtagata agaataaaca cctgctgaaa cttggcgaac
    26581 ataaccagca cgcaacataa gagcatggct gataacttga gcatcgcttg gcatttcgcg
    26641 aagcgttggg ataggcattt tactttgttt cataatattc ctcgattatc taaaaaagag
    26701 tcgcataatg tcattccaag tcacagcaat catcaagaca accatgatga ccactccggc
    26761 caaggtgaca taggtttcaa tttcttgttt caatggtttg cggcggatgg cttctaggat
    26821 attgagcaca atcttaccac catccaaggc tggaatcgga ataagattaa aaatcccaat
    26881 attgatggaa atcattgcca agaagtacaa gatattttca attccatttt tagcagcatc
    26941 actacttgcc ttaaagatag caacaggtcc acccaacttg ttcaaatccg gttggaaaat
    27001 cagatttttc agagctgaga gaattcggag agctgagtca gcagcagttg taaaaccacc
    27061 tacaaacatg gatagaaaat ctgacttaac ccccggttga acacctagaa ggtaacgacc
    27121 ttgactatct tcgggtgtaa cagtgacttg tttgtcactc cccttttcag aaatagtcac
    27181 atccaaagtc ggtgccgtct tatctttggt ttctgtttcc acagcttgga tcaagctttc
    27241 ccagttgcta acctcatgtg agccaatctt ggtaatttgt gccgtttctg gtactcctac
    27301 cttggccaag gcaccttggg gcatgatatg gaactgattg gtatcaacat ctctgacacc
    27361 accctgcata aagattaaaa cccaaaaaac aacgacacct aagataaaat tgttcatagg
    27421 acctgcaaaa ttggtaatca gtttgcccca gatagtcgca ttttgatatt gaacatctaa
    27481 aggtgcaatc cgaacctcag taccatctgc ttccacaacc gttgcatcgt gatccactgc
    27541 aaatgttttt tcttcttcca gaaccaatcc tttgataaag agcttgtctt caaaatcaaa
    27601 ctgggtcacc tgcataggga gggctgtttg atccaatttt ttacctgaga gattgatgcg
    27661 tttaacctta ccatcatcag caagtgtcaa actaacaggc gttcctgtct tgatttcagt
    27721 tgtatcatca ccccaaccgg ccatgcggac atagccaccc agaggcaaga ttcgaatggt
    27781 ataggccgtt ccatccttgc caatgtgagc aaaaatttta ggtcccatac cgatggcaaa
    27841 ttcacgtact aaaatccctg atttcttggc aaagtagaag tgcccgaact cgtgcaccac
    27901 tacaataatc ccgaaaacca gaataaaggt taaaattccg agcatagcgt ttcctccgtc
    27961 ttttgattaa aagagtccaa ataagtgcat gattggaaat acaagcaaca tactatcgaa
    28021 acgatccaaa acaccaccat gtccagggat aaatttccca gaatccttaa caccaaaatg
    28081 acgtttgatc gaactttcta gtaaatcacc aaattgtcca gcaatgctaa agaaaatagc
    28141 aaagactgac atcttgtaaa ttccatatgg aagagcaact gtactgtcaa ctatcataaa
    28201 gataatggtt actaaaattg ctcctaaaat accacccaag gcaccctcaa gggttttatt
    28261 aggcgatacc cttggtgcta actttcgttt cccatagttc atcccaacaa gataggcacc
    28321 actgtctgtc gcccagacga tacacaaggc taagagagcc ttgtccaaac ctgcaacacg
    28381 agcatctagt aaagcattaa acccaaagcc cacgtagaag ctcatagcaa gagggaaaac
    28441 cgcatcctca atcgtataag acttgctaaa aacggtcgtt cctaacatga ttgaaatcaa
    28501 aacactatag gcaaccacat tcccatcaac tggcaaaaaa gtcaggtaat tctccaaggg
    28561 aatggtcaat gcaaaggttg caaagagggt caagaggccc tccatcgtca tggtcgctag
    28621 acctctcatc ttcaaaagtt catgcatggc tagcatggct acgattccga ttgctatctg
    28681 aagcaagagg cccccaatca ttaaaattgg taggaaaata gccagggcaa tccctgcaaa
    28741 caaggttctt ttctgtaaat cctgggtcat atttcctcct aaactcctcc aaatcggcga
    28801 tgacgacgat tataggcaag aatagcttcc tgcaaggccg cttcgtcaaa atcaggccat
    28861 aaggtgtccg taaaataaag ctcactatag gctccctgcc atggaaggaa attgctcaaa
    28921 cgtaattctc cactagtacg gataatcaag tctgggtctc gtaagtcctt aggcaaatgc
    28981 tgggtaaaga gatagttacc aatcaattcc tctgtgatgt cacctggatt gattttggca
    29041 tctaaaacat cctgggaaat caacttaagc gcctgtgtaa tctcagcacg tccaccatag
    29101 ttaagagcaa aattaagaat caatcctgtg ttgttcttag tcaattcctc agccttggtt
    29161 aaagcttcaa aggtttgctt aggcaggcgg tctgtctccc caatcatttg aatcttaaca
    29221 ttattcgcat gtagttccgg gacataatta tcataaaact ctactggcaa gttcatgata
    29281 aacttgactt cctgatctgg acgggtccag ttttccgtag aaaaagcata gaccgtaata
    29341 accttgacgc ccagtttgtt ggctgccttg gtcacggttt gcaatgcttc catgcccgcc
    29401 ttatgtccaa aaactcgcgg ttgcatacgt tttttagccc aacggccatt gccatccatg
    29461 atgatgccga tatgagcagg aacctgtgtc ggaacctcta cttccacagc cttatctttc
    29521 ttaaaaaatc caaacatgat cttattccta ttcaaaaatc tatcgtttca ttataccata
    29581 tttccccatt ttcttctatc actaagctat ttattctcag gcaccaagcc catttttcaa
    29641 aaaaataagc cgcctgattg ggcgacttta tttttatagg gagattatta tgaaaaagtt
    29701 ttaggagttt aagttaaggt cttcttaact tatgaactta gtgtacactc cctagcttaa
    29761 agtttcctta agtattttta aaaatcaaat ttttccattt ctcctgccaa tttttcttgg
    29821 ataaacgtgt ttgatagagt tccattcggt cttcattttc taagaaatga ggagttggac
    29881 gaacttgaaa attcaaaata tcctccaaac cataaggtac atagagttca aaatctaatt
    29941 cttcattcaa gcgcagtcca actgccgtac accgttctgg atacttactc atagcatcac
    30001 gagaactggt ataggaagca gtgtgaggac tgtgctgatg catatagacc tgatttttca
    30061 attcccactg gtactgagga aaatcctctc tcagcttttt ctccagtaat aaggtttcct
    30121 cataagaaaa atctggatca aagaaaatca catctatatc tgtttcatga tcaaaagggg
    30181 atttgtctga caaaagattc cagatgaaat ttctgacaga acctgctgcc aaccacgagt
    30241 ctttcaaacc aaggtctcgg atgatcgtca gaatggccat catatctgga ctttctctaa
    30301 aagcctctaa gatttcttgc ttatttttca ctgtattcat aacctaagtg ctcatatgcc
    30361 ttagcagtcg ccacccgtcc agaccgtgtc cgcatgataa aacctttttg aatcaagtaa
    30421 ggctcataca tgtcttcaac tgtctcacgc tcttcggcga tattcacaga aagagttcct
    30481 agaccaacag gtcctccact gtacatctca atcatggtgc gaaggatttt ttgatccaca
    30541 tagtccaaac cttcatggtc aacatccagc atagtcaaag ccttatcggt aataacatca
    30601 tcgataaccc cattccccat tatctgggca aaatcgcgca cgcgcttgag gagacgattg
    30661 gcaatacgag gggttccacg actacgtagg gccaactcag atgctgcctc atgggtgatt
    30721 tccatctcaa aaatatctgc cgtccgctcg acaatttctg tcaagtcagc atgagcataa
    30781 tactccatat gacctgtaat cccaaaacgt gcccgtagtg gatttgagag cataccagcc
    30841 cgagtcgtcg caccaatcaa ggtaaaagga ggcaactcca aatgaacact gcgactgcct
    30901 tcaccagccc caatcataat atcgatgtag aagtcctcca tggcactata aagcacttct
    30961 tccactgaca tgggtaagcg atgaatctcg tcaataaaga ggacatctcc aggctctaaa
    31021 tcattcaaaa tcgctaccaa atcacccgct ttttcgataa caggaccaga cgtttgcttg
    31081 agattgactc ccagttcatt ggcaatgaca aaagccatgg ttgttttccc aagccctgga
    31141 gggccaaata agagcacatg atccagcgct tcatcccgca ttttagcggc ttcgataaag
    31201 atctgaagtt gatccttaac cttatcctga ccaatatatt cacgtaaata ctgaggacgg
    31261 agcgtgcgtt ctactaactc ctcatcaccc atcatctcat tatctaaaat tctactcatg
    31321 gctctattat atcaaaaaaa acaagccaca aacaaaaaag ccacctgatt gggtgactcc
    31381 taagtttagc acttatgtgg tataatatta tacggcactt ctacaccgcc tacgaaagga
    31441 ggtgagatag cccatgatgg aattagtact caaaactatt atcggaccaa ttgtggtcgg
    31501 tgtcgttctt cgtatagtcg ataaatggct aaacaaggac aaatagtgtc aaaaaagacc
    31561 tcaagcttat ttggtcgtga gcttggggtc ttttctagcc tatgatatag aactagtact
    31621 caattccttt ttattatccc atagttcacg aattttgtca aaactttaca ttttcttcaa
    31681 ccgctgtacg acaagacggt taagattaag agaacgttag ggattctatc aatttcatag
    31741 aaattttgat ttcgtaaacg aagagacaat cttacatgtc acttctcatt taatacgcca
    31801 ctactagaca agcaaaatca ttattacagt agttccagtc cttcaattaa cagtcactta
    31861 caatcaaatt gagtttgaac tagctgaagc gaccacagac ctatttctta gtcatattcg
    31921 ctaaaaaaat ccccgccaaa atctcaaaaa gtccccgcca attccccgac caaaatccga
    31981 aaaataccga aaaatatcga aaaattattt ttagaatagt cccaaaaatc ctgaaataga
    32041 gctaaaaaac tccacctgat tcggtggagt taagggagat tattatgaaa aagaaaagtt
    32101 taggatttta ttaaataaag ttaggaggtc tttatttaat aactacatga tacaagacga
    32161 aacttaaaac tagcttaact tttctaaaat tttactattt tgcaaaaaat ttctatcacc
    32221 agcacctcac caatcgagta ggggataatc tctagcccct ctcacaccac cgtacgtgcc
    32281 gtttggcata cggcggttca actaactttt aacgcatgtc gttcaaggta ataatccaaa
    32341 cacgaaacca gtccacgttt ttccaggact ggttttgata tagcacgttt aagtaccgac
    32401 ttctgagcta ctaattgata atggtcgccc cagccagata ccttatctgc tatccattta
    32461 ggaactccta acttaagcaa tccccataat cgtctcgatt tcttcttcca ttgcttccag
    32521 ataatcactc gtaggcgagt acgcaagcgc tcatctatgc tggcgactat acttttcata
    32581 tttcccaatg agcaatagtt tatccatcct cgaatagaca aattcagttg ctcaatacgt
    32641 cttgttaggt ctatactcca tttcctctgt gttagtttct tcaatttaaa cttaaatctc
    32701 cgaacactat cttgatgtgg acggcttttc caaccatctg ataatttcca gaacccaaaa
    32761 cctagatatt tcaactctct tggtcatgtt tactttcaaa cctagccgtt tctcaataaa
    32821 acgactgact gaatacatca tacgcttagc ggctgcctcg cttacgaccg taatcacaca
    32881 atcatctgcg tagcgcacaa atcgaagtcc cctcttttct aattccttgt ccaattcatt
    32941 aagcatgata ttggataaga gaggagataa atttcctccc tgtggtgtac caactagtgt
    33001 tttataacgt tgaccattaa tgataacacc tgaatgaaga tacttacgaa tcaaggattc
    33061 cgtatctccg tcttcgataa tgttatgtac taaggacatc aatctatctt gaggaactgt
    33121 atcgaaaaat ttctctaggt ctatatccac tatccactca tagccgtcat ttaagtattc
    33181 taagagcttc atgatggctt tttcacatga cctatttggt ctgaaaccat aactcgtatc
    33241 tgagaaatgg ggttcacaaa tggggctcat gacttggaca atggcctgtt gaatcattct
    33301 atccataact gttggaattc ctagttgacg gatgcctccg tctggtttag gtatctcaac
    33361 tctaagaact ggttgaggct tatattttct ctgttttatc agttccttag tcaagcgcca
    33421 gttttgtctg agataattat ccatctcttc gatagtcatt ccatcaatcc cagctgagcc
    33481 tttattggat tttacttgat tgtaggcttc cagcatattt tcgcgtgata atatcttatc
    33541 tagcagtttt gacatgtgcg tattcctttc ttattttggt gcctgaggga catcttatat
    33601 tggtgaacct tcatctagtc attacgtgtc aaagtccagt tctatcagac cactcatttt
    33661 acagacacaa gtgaagtagg attacttcga ttagttgttc accccttcgc tccacttcca
    33721 ttacggaagt ttcctcacta ctatgggctc ggctgacttc tcatgattcg ttgttactac
    33781 gctttcagcg ctcatgaaac ctcacgggat aagtcgtaca tctttcctcg tttatacaag
    33841 atatgaggac gttaaaaggt tacagtgaaa ataggaaatc tgacgcagag tctttagact
    33901 ctagaaagat ttatcttttt cacacaaacc ttagtccgaa ttcaattact ctcgtgattt
    33961 acacatatag gttacgacta cctttttgga ctttagagtt tgaagcctcc ttatccgcta
    34021 tatacgcctt actatcacgt tcctgttcgt agagccacga tttcgctatc ccttcctctc
    34081 cctgctacct cacgatagtc aggctgagga cttacacctc agatatacga catgcccgtc
    34141 gtaccgcaaa aaagccacct gattgggtgg cttcattagg agattgtgat gaaaaaagtt
    34201 taggatttta ttaaataaag ttaggaggtc tttatttaat gactatatga tactagacca
    34261 tccttaaact ttgcttaaga acaaacaagt ttttttattt ttctctgttt atccaaatca
    34321 ttcctgtaca gtcataggtg gataagattt caaagcccat agaacgataa aatcccacgt
    34381 ttttttctgt ctcttctgtc gccagctgga cttgataggc ctctttaaaa tttcctaaag
    34441 cctctttcat caaggagcta ccaatccctt gacgctgata gctaggcaaa acaatcaaat
    34501 cctgtacaaa aactgatgaa aaaccatctc caaccaaacg aatcaagccc accacagcat
    34561 caccatcaag tgccagataa attactaatg aatgagataa ggcctgctcc agcatctctg
    34621 tttgatgggt atagtttgtc caaccgacat cctgatagag atgcaaaaca tcctctagct
    34681 tgacaatttc ttgcttttta atagtaatca tctcaacacc tcttaaagtt ctctcaagct
    34741 cttgtgctgt cgtccatttt tatcaaagtt ttcaggacgc aaccatattt ccaatcgagc
    34801 tttgacttga ggccagtcct tatcaatcat agacaaccaa tccgtatctc ttgtacgccc
    34861 cttataaacc actgcctgac ggaaggttcc ttcataaata aatcccaaac gttccgctgc
    34921 tcgtctggat ggcaggttaa gagcatcgca tttccactca tagcgacgat agttaagctc
    34981 ctcaaagaca tagcaagcca agagatactg ggcttctgtt cctatccgtg tccccctgag
    35041 ctctggagaa aaagtgacag ctcccacttc tattactcgg ttattctgat caattcgcat
    35101 gagggaaaaa gttcccaaag ccttaccagt tgccttgtct atgattgcat aataaaaacg
    35161 gtccttacga gccaacatct gatttaaaag gctgaccagt tcctccatgt ctgctactga
    35221 ctcctgaaag aggtaggtcc acatctcccg aggcgtatca gggccataaa cagctaataa
    35281 atcctccgca tgcttttcca ctgaaagagc ctctatccta gcataacgcc cttctaagaa
    35341 atcaaaagaa ggcaattcac ctggagtata agcttccatt gactccccaa tcatttgacc
    35401 atattcattt actggcatct tattctcctt atttcacttt tcaaacttta tagttgccca
    35461 tagtatatca tactttcata agaagattca aaaaatcctc cagattctac tctgaaggac
    35521 tcctatctta tttcaaaaca atattaacga gtttaactgg ctcaaacagt ttaggaaact
    35581 gtccgagatt tgaaaccagc aaataaattg gttatttcac aacaatatta accaatttat
    35641 tcggtactgc aatcactttc acgatttcct taccgtcaat ttctgctttg actttttcat
    35701 ccgctagaga aatttcttgc aattcttcac gtgataagtc tttagcgacc atgagtttgg
    35761 cacggacttt acctttgatt tggacaacga tttcgatttc gtcttcaacc agtttacttt
    35821 cgtcccaagt tggccaagct acataagaga ttgactcacc tgtttctgcg actgtttgcc
    35881 agagttcttc tgccaagtga ggtgcaaatg gtgcaatcaa ttgaataaag cctttggcat
    35941 agtcaacata aagcttatct tccttgttag cagcattgac aaagaccata agttgggcaa
    36001 tagctgtgtt gaatttgaga gactcaattt gctcagtaac agctttgact gtttcgttgt
    36061 aagccttgtc aagagcacca ttgttttccg caaggatttc tttacttgta atcaaacggt
    36121 aaactcggtc aaggaactta cggcttcctt ccaaaccttc ttctgaccaa gcaatcgaag
    36181 cattgagtgg tcccataaac atttcataaa cacgaagggt atcggcaccg tattgttcca
    36241 ccacatcatc tgggttaaca acgttcttga gcgatttaga catcttggct ggcgcttgct
    36301 ccaactcttc ccctgtttct atatgaaaga aggaaccatc acgtttttca accttgtcgg
    36361 ttgccacaag agcaccacgg tggtcacggt agcttgttcc caaaatcatc ccttggttaa
    36421 agagtttttg gaatggttcc ttagtcggaa caacaccgag gtcatagagg aatttatgcc
    36481 agaaacgagc ataaagcaag tgaagtacag catgttccgc accacccacg tagatatcta
    36541 ctggcaacca ttgtttgagg aggtcctcat cagccaattt ctcagtattg tgcgggtcaa
    36601 tatagcggag gtagtaccag cttgaaccag cccattgtgg catggtgtta gtttcacgac
    36661 gacctttgac accatcttca cgagtcactt caagccaatc tgtcaagtta gctagtggac
    36721 tttcaccagt acctgaagga cggatatcct tggttacagg caagacaagc ggcaattcag
    36781 tttcaggaac agctgttgaa gttccatctt cccaatgaat gattggaatt ggctcacccc
    36841 agtaacgttg acggctaaag agccagtcgc ggaggcggta ggtaaccttc tcctgaccac
    36901 agcctttttc ttccaagcaa gccacaatct tggcaatagc gtcttctttg ttgagtccat
    36961 ctaggaagtc tgaattgaca tgaagaccat cctctgtgta ggcagcttct gctacatttc
    37021 caccttcaag tacttctacg attggaaggt caaattgttt ggcaaattcc cagtcacgtt
    37081 ggtcatgggc aggtacagcc ataacggcac ctgtaccata gctagcaaga acgtaatccg
    37141 caatccagat tggaatttcc ttaccattga caggattgat ggcataagca ccagtccaaa
    37201 cccctgtttt ttctttggca aggtctgtac gagccaagtc tgatttcaga ctggcttggt
    37261 gtttgtagtc tgctactgct tctgcttgct ctgtgcttgt gattgcatct actagttcat
    37321 gctcaggagc caaaacggtg aaagtcgcac cgaaaagagt atcaggacga gtggtaaaga
    37381 cggtgaattc cttgtctgtt cccttaactt taaaagttac attagcacca gttgatttac
    37441 caatccagtt gcgttgcatg tccttgatag actctggcca gtcaagctcg tctaagtcat
    37501 tgagcaagcg ctccgcatag gccgtaattt taagcatcca ttgacgcatc ggcttacgga
    37561 caactggata gcctccacgc tcagaagttc catcaggaag cacttcttca ttggcaatgg
    37621 ctgttcccaa ctcttccacc cagtttactg gcacttccgc ttcataggcc aagccttttt
    37681 cgtaaagctt agtgaaaatc cactgagtcc acttgtagta gtttggatct gttgtgttga
    37741 cttcacgatc ccagtcataa gaaaatccaa gcgcattgat ttggcgtttg aagttggcaa
    37801 tattttccgc tgtaaattct gctgggtcat tacctgtatc catagcgtat tgctctgcag
    37861 gcaaaccaaa agcatcccac cccattgggt gaagaacatt gtagccttgc gcacgtttgt
    37921 aacggctgag gatatcggtt gcggtataac cttctgggtg tcctacgtgc agacccgctc
    37981 cagacggata agggaacata tcaagcgcat aaaacttcgg ttttgatgca tctgttcctg
    38041 tcttaaaggt atgatgttct gcccagtagc cctgccactt aggctcaatt tctttatgat
    38101 tgtaaaaact catggtctct ctccaatttt gtgatgttac tattatacca tttttgaggg
    38161 aatttgaaat gtgtttaaag aaaaaactgt atactgtatc tcattaattt tgatgactat
    38221 gaattgctct atctcccact ttttatccca ttgttatgca gtaaatcaag gagtaagtca
    38281 agaaacttat ctcgtatagc acaaaatact tattttagac cgaagataaa actggaatgc
    38341 taattaatgt attcacaata aatagccgac aacctatgtc gctttttgat ttatgaagaa
    38401 cgtatagtag actgaatctg aaatagtacg aaacaattgc taaaacattt atagaaatta
    38461 attttacttt cccaatcgat ttgttctcat cctatttcaa tcttctatag aattcaatac
    38521 ggggatcaat aaaagactac catttggaaa acagtagtcc ttattgttta ttttgaattt
    38581 acataggcat ctacagcgat aatagcttga gcaacatctg aaggcgaaat cttaaacggc
    38641 atctgatgaa ttgtctcacc ctccatagtt gcttgtttac caacttttat taaatcatca
    38701 tatccaactt gatccaaatg catttctttt agagttgttg gcataccaat ttttttgtaa
    38761 aactcaatat acttatcaag ttcttcttta ggtctatttt ccaataatag ttgtactaaa
    38821 gttccataag ctactttttc accatgtgtt aaatgatgaa tgtcacctgt caatgcagta
    38881 aaaccattat gaattgcatg cgccgcagct aatcctccac tttcaaaacc tagaccactc
    38941 aataaagtat tagcttcaac aatattttct aatgctggtg tcaccacttt agcttcacaa
    39001 gctgccatag cctgtaaacc atctgcaaac agcgtttctt cacatttctt cgcaattgca
    39061 actccagcca atgtttgctg ttgtcccaac atagtttttc catttgcctg cataaccgca
    39121 cgcgcctcaa cccaagttgc taaaccatct gcaataccag acgctaataa acgcttaggg
    39181 gcttgtgaaa taacttttgt atcaaccaaa actaaatctg gatttttaga ataaaataga
    39241 taatgatcaa atgcaccttc atctgtataa ataacagata aagcagatac aggtgcgtcg
    39301 gtcgatgcaa ttgttggagc aataataaca ggcttttcaa tcaaatctgc aatagctttt
    39361 gcgctatcaa tcgtctttcc cccaccaaga ccgataatac tatcacaatt ttctttctca
    39421 gccaaggcaa caactcgatt gatttcattg tcagaagctt caccattaaa tagcgccaga
    39481 acaatatgga aaccatacct atgtaggtaa tcttcaaatc gttttccaac aatatcataa
    39541 accaactgat cgcataatag aatagggtaa tttcccaaat ccaaaattga tttggcattt
    39601 tcaaacaagg cattttcccc ctgaatatat ctagaaggac tagcaaaaat tctcatatat
    39661 atttcctctc tatctaaatg gaacgactat tttgagtaac aaaccaatcg tcagaaaaat
    39721 catcaaccgc cttttggata gatggcatgg cgaaagctga ttcaaaaaca tctgctcctg
    39781 ctgtaacagc atgcgcacct gcagctaaag cattatttac ttgtgctaca tttttaaagg
    39841 atgcagctaa aatcttacta ggagagttct gtctatcaat agcaagagct aattgacgaa
    39901 tgacagaatt tgaatcaatg ttcagatttt ccattctatt ataatatgga gctaggtaat
    39961 cagctcctgc ttcgatagct aataatccct gaataactgt ataaatagct gttgcagtga
    40021 tatggtagcc ctcttttttt agcaccttta ttgcacgtaa tccagctgga gtaacaggta
    40081 ctttgataaa tatatcatct cctgcttgtc ttcgaatttc atgagcatcc tttaagatgc
    40141 cttcaaaatc ttgagaaatc acctgaacat gaatagaggg tgtagagcca atcaattctc
    40201 ttacatcttt gattcgttca aaaaaattaa tagaaccctc tctttttgca atagtgggat
    40261 ttgaagttac cccagctagc ggcaaaattt cagaccactt tttaatctca tctaaattta
    40321 atgtgtcaag cataaattcc ataaaaagaa cctctttatt ttacaaagta tgctcagtac
    40381 gtcctataat gtcatcttgg gttgccttag aaagaacatt gaagaatgca gagtatcctg
    40441 caacacgaac aattaagtct ctgtgttttt caggatgttt ctgagcgtca atcagcgtct
    40501 ctctggaaac aacattgtat tgaatatggt acccatgtaa acgattaaag aatgttcgta
    40561 acaaagcaat tagttttaat ttatcttctt ctttggctaa cgtttgagga tttactttct
    40621 gatttaagag aaccccacct acgatttcat ctgttggtaa ttttgaaaca gattttaaaa
    40681 cagatgtagg gccgtgttga tccatattat gtgatggtga acaaccctct gctaacggtg
    40741 tacccgcgtt gcgtccatct ggagttgcta atgttccacg tccctgccct acgttggctg
    40801 agatagaaga tgttcctgaa taacgaattc ctccaatagg ccctcttcca taacgtgtat
    40861 taggatattt agcaatttca tcaacataaa tgtcataagc agcagtaacc aatttgtcag
    40921 cataatcatc atcattacca tacttaggtg catcatgaat caacatttct tgaatgacct
    40981 taccttcttc tccggcataa tctgtttcca gtgcatgcca aagttgactt gggcttatac
    41041 gttcttcctc aaacaccaat tttttaattg cagctaacga atccgacaaa tttgcaattc
    41101 caacttgcaa tcctgatata taatcatata ctgctccacc ttctttaagg tgttttccac
    41161 gaccaataca atcatcagtc aatgctgaac atagaatatc aggaacttct cgttccaatg
    41221 ataaatcaat agaattttca acaataacac tcattcgtgt caaatatctt agtgttttat
    41281 cccaagcatt ttctaattca gaaaagttct tcatatcctt aaaatgacca aagcttggtg
    41341 caaaccgttt acccgaagcc ggatcaattc catcattcat cgtgataagt agaaccttag
    41401 ggaagttcat ataactcata cctgtgcaac gatagcccca tttccctgga actgccgttt
    41461 caacacatcc aatggcactg taatcataag catcatcttc caatactcct tttgcaataa
    41521 aagaaggaat aataatctca tcattattaa atgcaggcat accaaaacca agtttcatca
    41581 cttcaataca ctcattcatg aaacgagcat ctaaacctgc atggtaacgt acagttagat
    41641 taggttgcgg tagatgggtt tgtgcaactg attttaatac caaataagat aatgggttaa
    41701 cagcatcctt cttatctcga gtctgtccac caattgtaac attttgatat aaaggacttc
    41761 ctgctgaaga aaatgtatgt gattgactgc gaaccttatt aattgtaatt gtcttaatcc
    41821 aaagatttgt cagacgttca acaatgctat cttctgtttc tttaccactt tctaaatcag
    41881 ccttcatata tggatacata tattgatcaa aacggccata tgaaagagag tggccattag
    41941 attcaatttg taaaatacat tgaataaacc aaactgattg aatagcttct gcaaaagtag
    42001 ttgccggttc atatgggact ctagagcaaa tatctgcaat ctcaagtaat tctttcttac
    42061 gtttaggatt tgcattttcg gctaaacttt tagcaagagc aacaaagcgc tttgcatata
    42121 ctttaatagc atcgattacg ataaatatag agtcgtaaaa atgatattta tcaatacttg
    42181 ctggatctgt taaatctaga gctacttttg ctttacgagc ccgctcttca aaacctctta
    42241 aaccaaattg caaaagtttc tgatagttaa ctgctaagtg agcatctcca gaattcatct
    42301 taccttccat accgaagaat cctgtttcca tataaactga cacttcttca ggtaataagg
    42361 caccagctct agcacgtaaa ttattatttt cccaaaacgg agcaatactt ctaagttgtt
    42421 cttttgtttc ttctgtaata tagaaaacat ctccatcacg cttttcaaaa agatccaact
    42481 cattgagaac aaattctagc gtatattccg gaaaaatagg agcatcttta ttggaagaag
    42541 cttgatttcc cgcaatcata gattcttctt caatatagat agacatattt tccaaaattt
    42601 ctttcagcat atatgcacgt tttaggacat taggttgttc cttgtatcgt tcataggcgc
    42661 gtgttgctag aactgctctc tcagcatcaa tataaggttt tttatttaaa acatcttctc
    42721 gatatttgtt catcctttca gtaaggctgc caaaatattc tgtcttgatt gttgttcttg
    42781 ctacttctgt atttaccatc gtaagcacct ttctttcgaa aatattttta tttctttcga
    42841 aaatataata ccgattttta tagaaatttt caagctttta actagaaaaa ttttaactct
    42901 ctaattttta gcacaaatgt gtgagtttaa cagtaacaca caaatacctc taagattgtt
    42961 tgatttcatt ttggtaagct aaacgatctt gtatcttaaa gaatggaaag taaaccactg
    43021 tagatatcac caatactaat aactgagtca caacaccttg ccatccaccc accaaaaatc
    43081 ctgatagaat agctggtgta ctccaaggca atgttacccc tgagaatggc tgcatgaaac
    43141 ctgttgcaat agctccatat actatcacag ctgcaagtac aggaacaaga atgaaaggta
    43201 caaacataac tggattcatg acaatcggaa atccaaatac aactggctca tttacgttaa
    43261 atattgctgg aaaagctgca acttttccta aggcttggta ttgttttgat tttgctgcaa
    43321 aaagcatggc aactacaaga ccaaacgtaa tccctgaacc tgatagaatt aaaaatgaat
    43381 ctaaaaattg ttgagtaaca atatgtgcac cattttctaa tgatagatta gcagaggcta
    43441 acatagcttt attagcgtca agattagata aaagcagagc tgtcactact ccatttacta
    43501 ccgattgccc atgaacacca aaccaccaca aaaatgatat aaagaatgca attccaatag
    43561 caccatacaa agatccagtt aaaccttgca acggaacttg aatagcagaa taaatcattt
    43621 ctatgaatgt tccgccatta gtcaatgact tcgctaaaat atatacaatc atagaagata
    43681 agaaaattac aaatgctgga atcattgctt caaactgttt ggcaatagct tgtggaactt
    43741 gttctggcat cttaataaca atttttctct ttataaagaa ggtataaata cttcctacta
    43801 ccaaacctat aatgatagca ccgataattc cttggcctcc aaaccaaact ttactaatag
    43861 cgtccccaat cgcctcacct tgtttaggga tataagatga tcttagcaaa ataaagaatg
    43921 cagatacaga tagaactcca gctggtaaag cctctactcc gctattctta gcataagaat
    43981 aggcaattga aaaacaagaa attagaccca taatagcaaa agttcctgaa tatacttgca
    44041 taaacggctc tgtccaatta gctccaaaaa cactagcaat gctcttattt aatccttcga
    44101 acggcaattg tcccataatc aagaacaaac tgccaactac tgtcaatggc aaaattgcta
    44161 acatcccatc ttttagagct ataatgccac gcatattcac aaacttcatc atcggtgcaa
    44221 tgattttctg aacatccatc tttgacataa taaatctcct tttcttaccc actaatcaaa
    44281 gatagggcca aatctaatac ttttttccca tctaacatac catagtccat catcggaata
    44341 acagctatcg gaacatcaca cttatcacaa atttcttttg atttatctaa tgtataagca
    44401 acttgtggac ccaatagtgc aacatctata tttggcgcat aatccgctaa tttagactga
    44461 gaaaacgcct ctatttctgc ctcaactcca ctagattgcg ctgcaatttt catattattt
    44521 acaagcatac cagtagaaaa acctgctgca caaaacaaac caatcttcac cattatgttt
    44581 tcctcctcta tgttaataac aatgataata ctctagtatt attttttatg aagttctttt
    44641 ctcaaactaa taatttcttt gattaaatta atctccgtca tactagtcat gagatgatct
    44701 tgtgaatgaa caaagagagc tgtaatttct gtctttgtac cagacgcttc ctgtgccaag
    44761 aattttgttt gtagattatg agcttctaat aaggctgcat cagctaactg gatttcttct
    44821 tcacaccgtt cacatgtacc attttttatg taatctaacg ctttataaat atgttgtttc
    44881 gcatcaccag catataaaat taaacccatg ataatttgat ctggaacaat aatttccata
    44941 aattcctcct catttcacta tgtaaaaagc ttttttcatt tgaaatttta aaattttctt
    45001 ttgtaactat agaatacaac tacataataa agttgtcaat ccaaaaacaa cagataaact
    45061 atttttgttt atataagcac aaatgtgcaa tcaactaaaa agaaaaacga taaactgaat
    45121 cagtctatca ttttcactca cctagaatct ctctaaaagt caaatcccca tcttcttcca
    45181 aaacttttaa aattgtattt ttgtctgtaa tcaaatgatt tactaaatta gcacgcaaga
    45241 cagaaagaat cgaagatact ttcgtatcac cgtaagcaac agctaaactt tgaggaatat
    45301 tttttaaatc ttccaaagag attgctatcg ttctttcctg taagttttca tagacttctt
    45361 taccttttga atcaaaaaat cgacaacaaa tttctcctac agttttaact ttggtcaatt
    45421 ctttaaagtc atcctctgta agcatgtcta accattgatg ctttccttta ttgctaaaat
    45481 caccaattcc gactacagct atatctaaat ctttccaact atttttcaaa ttttcaaaat
    45541 atcttgattg caaaatacca tctgctaaca atttattttc ttgcacaatc gttgcattca
    45601 taaatgtaca ctctccatga aattttctag acatttcata aatcagtgta ttcacatggt
    45661 atttagcgtg tatgtgacta ggaccacctg ctagaggata gaagtgaaca tttcggacac
    45721 ttttactgtg aattaaatct actaaattac ttaaactttt cccccaagaa aagccaattt
    45781 tcatattatc atcaattaga ttcctaagga cacctgctgc aacttgagaa attctttcag
    45841 ataaaattgt tggattatca tcaaattcat ttggaataat ttctaaactt tccagaccat
    45901 atttttcttt tacataattt tccaacttaa acatattggt atcaaaattc tctatttcaa
    45961 ttttaacaat tcctgcattc cttgcttctg ttaacattct actaatagag gttctataaa
    46021 ttcctaattt tgctgctatt tgtgactgat ttaagttttc aatataatac agataagcaa
    46081 ttttagagag cagtttattc ctatcttgat tcatacattt aacctcttac gaaactacct
    46141 taaccattat cccagcattt tctaatgtag ctatattttg tttagaaagt ttttcgtctg
    46201 ttattacttc atagacttga cttaaagcaa atcttcttac tgtacccctt ttatcaaatt
    46261 tacttgagtc agttagtaca atgactttat ccgacgctgc tgaaatatat tgaactacct
    46321 cactgcgcat taaatctttt cctgtaaagc ccatctcttt atcgtaacca tctgtcccaa
    46381 caaaagcttg atgcacatga aaagtctgta tcatttcttt taataaaggt cccacagtaa
    46441 cctgtgaatc cttctgaaac tctccaccaa gaacaataat acgacatgaa tcataagctc
    46501 tcacaaaatt tgctataaaa aatgaatttg ttacaatcgt aacatttctt ttttgcttgc
    46561 aaatttcctc agcaagtaaa gcacaggtcg atccagattc tatcattatt gtttcattat
    46621 ctgacaccaa ttttactgct tcctgaacaa tttttctctt aatttcatag ttaattgaca
    46681 aacgtacatt taagtcatct ccactattta atacagcata tccatgctct ctgtgtaata
    46741 aaccttttga ctctaattta tctaaatctt ttctaatcgt tactttcgat acatttaatt
    46801 tttccgataa tgtattaacg tcgatctttt catattctga tactaattta ataatttgtt
    46861 ccaatctttt cattttacac ctccgtttta ttctaccaaa ataaaaagca aaaaacaaca
    46921 aattaaactt tcgttcgtaa ttgtttttct ttcgtttttg tgataggata gacttatgaa
    46981 gaggaggaac tcttatggaa atatctaaag gaattatttt taatattcaa cacttttcaa
    47041 ttcatgacgg cccgggtatt cgtacaactg tttttttaaa aggatgtcct ctgcgctgtc
    47101 catggtgttc taatcctgaa tctcaaagaa tgaaacctga aaaaatgaaa gatgctcaac
    47161 gagagaaatt caccttagtc ggtgaagaaa agactgtaga agaaattatt acagaggtat
    47221 taaaagacaa agaattttac gaagaatccg gtggaggttt aactttatca ggaggtgaaa
    47281 tatttgctca gtttgaattt gctaaagcca tcttaaaatc agctaaagaa catcacatac
    47341 acactgccat tgaaactact gcctttgttg atcatgaaaa atttattgat ttaattcaat
    47401 atgtggattt tatctacaca gacctaaaac attataattc tataaaacat aaaaaagtga
    47461 ctggggtttt taatcaaatg attattaaaa acattcatta tgctttttct caaaataaaa
    47521 ctatcgtttt aagaatccca gttattcct
//
LOCUS       DAVMCN010000011        41788 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVMCN010000011 DAVMCN010000000
VERSION     DAVMCN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.011"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(412..2139)
                     /gene="ezrA"
                     /locus_tag="VYP85_000750"
     CDS             complement(412..2139)
                     /gene="ezrA"
                     /locus_tag="VYP85_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1881295.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2221..4167)
                     /gene="gyrB"
                     /locus_tag="VYP85_000751"
     CDS             complement(2221..4167)
                     /gene="gyrB"
                     /locus_tag="VYP85_000751"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1881296.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4182..4745)
                     /locus_tag="VYP85_000752"
     CDS             complement(4182..4745)
                     /locus_tag="VYP85_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1881297.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4830..5384)
                     /locus_tag="VYP85_000753"
     CDS             complement(4830..5384)
                     /locus_tag="VYP85_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1881298.1"
                     /translation="MVKVAVILAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5395..6618)
                     /locus_tag="VYP85_000754"
     CDS             complement(5395..6618)
                     /locus_tag="VYP85_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1881299.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6655..9105)
                     /locus_tag="VYP85_000755"
     CDS             complement(6655..9105)
                     /locus_tag="VYP85_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1881300.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9305..10234)
                     /locus_tag="VYP85_000756"
     CDS             complement(9305..10234)
                     /locus_tag="VYP85_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1881301.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10374..10661
                     /locus_tag="VYP85_000757"
     CDS             10374..10661
                     /locus_tag="VYP85_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1881302.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10695..12029)
                     /gene="ciaH"
                     /locus_tag="VYP85_000758"
     CDS             complement(10695..12029)
                     /gene="ciaH"
                     /locus_tag="VYP85_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1881303.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12019..12693)
                     /gene="ciaR"
                     /locus_tag="VYP85_000759"
     CDS             complement(12019..12693)
                     /gene="ciaR"
                     /locus_tag="VYP85_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1881304.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12802..15348)
                     /locus_tag="VYP85_000760"
     CDS             complement(12802..15348)
                     /locus_tag="VYP85_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1881305.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFFAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVTSQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLTAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15471..15911)
                     /locus_tag="VYP85_000761"
     CDS             complement(15471..15911)
                     /locus_tag="VYP85_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1881306.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(15886..16755)
                     /locus_tag="VYP85_000762"
     CDS             complement(15886..16755)
                     /locus_tag="VYP85_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1881307.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16733..17233)
                     /locus_tag="VYP85_000763"
     CDS             complement(16733..17233)
                     /locus_tag="VYP85_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1881308.1"
                     /translation="MEIKKHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17244..17942)
                     /locus_tag="VYP85_000764"
     CDS             complement(17244..17942)
                     /locus_tag="VYP85_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1881309.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17935..18171)
                     /locus_tag="VYP85_000765"
     CDS             complement(17935..18171)
                     /locus_tag="VYP85_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1881310.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18271..19197)
                     /locus_tag="VYP85_000766"
     CDS             complement(18271..19197)
                     /locus_tag="VYP85_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1881311.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19272..20087)
                     /locus_tag="VYP85_000767"
     CDS             complement(19272..20087)
                     /locus_tag="VYP85_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881312.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20091..20411)
                     /locus_tag="VYP85_000768"
     CDS             complement(20091..20411)
                     /locus_tag="VYP85_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1881313.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20663..20743)
                     /locus_tag="VYP85_000769"
                     /pseudo
     CDS             complement(20663..20743)
                     /locus_tag="VYP85_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20787..22784)
                     /gene="metG"
                     /locus_tag="VYP85_000770"
     CDS             complement(20787..22784)
                     /gene="metG"
                     /locus_tag="VYP85_000770"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1881314.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFCLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22908..24167)
                     /locus_tag="VYP85_000771"
     CDS             complement(22908..24167)
                     /locus_tag="VYP85_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881315.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24169..24870)
                     /locus_tag="VYP85_000772"
     CDS             complement(24169..24870)
                     /locus_tag="VYP85_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881316.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24854..26053)
                     /locus_tag="VYP85_000773"
     CDS             complement(24854..26053)
                     /locus_tag="VYP85_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1881317.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVANEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26339..27685
                     /gene="gor"
                     /locus_tag="VYP85_000774"
     CDS             26339..27685
                     /gene="gor"
                     /locus_tag="VYP85_000774"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1881318.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            27881..28417
                     /locus_tag="VYP85_000775"
     CDS             27881..28417
                     /locus_tag="VYP85_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1881319.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQTYFTN"
     gene            28473..28553
                     /locus_tag="VYP85_000776"
                     /pseudo
     CDS             28473..28553
                     /locus_tag="VYP85_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(28622..28837)
                     /locus_tag="VYP85_000777"
     CDS             complement(28622..28837)
                     /locus_tag="VYP85_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1881320.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28935..29255
                     /locus_tag="VYP85_000778"
     CDS             28935..29255
                     /locus_tag="VYP85_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881321.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29285..29623)
                     /locus_tag="VYP85_000779"
     CDS             complement(29285..29623)
                     /locus_tag="VYP85_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881322.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29635..30354)
                     /gene="trmD"
                     /locus_tag="VYP85_000780"
     CDS             complement(29635..30354)
                     /gene="trmD"
                     /locus_tag="VYP85_000780"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1881323.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30344..30862)
                     /gene="rimM"
                     /locus_tag="VYP85_000781"
     CDS             complement(30344..30862)
                     /gene="rimM"
                     /locus_tag="VYP85_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1881324.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30893..31681)
                     /locus_tag="VYP85_000782"
     CDS             complement(30893..31681)
                     /locus_tag="VYP85_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1881325.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIYDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPIFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(31785..32028)
                     /locus_tag="VYP85_000783"
                     /pseudo
     CDS             complement(31785..32028)
                     /locus_tag="VYP85_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(32258..32497)
                     /locus_tag="VYP85_000784"
     CDS             complement(32258..32497)
                     /locus_tag="VYP85_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1881326.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32517..32789)
                     /gene="rpsP"
                     /locus_tag="VYP85_000785"
     CDS             complement(32517..32789)
                     /gene="rpsP"
                     /locus_tag="VYP85_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1881327.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLTWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32959..33168
                     /locus_tag="VYP85_000786"
     CDS             32959..33168
                     /locus_tag="VYP85_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881328.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33647..33838
                     /locus_tag="VYP85_000787"
     CDS             33647..33838
                     /locus_tag="VYP85_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881329.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDF"
     gene            33952..34755
                     /locus_tag="VYP85_000788"
     CDS             33952..34755
                     /locus_tag="VYP85_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1881330.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34811..36352)
                     /locus_tag="VYP85_000789"
     CDS             complement(34811..36352)
                     /locus_tag="VYP85_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1881331.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHDPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36354..36836)
                     /locus_tag="VYP85_000790"
     CDS             complement(36354..36836)
                     /locus_tag="VYP85_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1881332.1"
                     /translation="MVKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            complement(36836..37921)
                     /gene="rlmN"
                     /locus_tag="VYP85_000791"
     CDS             complement(36836..37921)
                     /gene="rlmN"
                     /locus_tag="VYP85_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1881333.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCSSGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(37942..38472)
                     /locus_tag="VYP85_000792"
     CDS             complement(37942..38472)
                     /locus_tag="VYP85_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1881334.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(38629..39234)
                     /locus_tag="VYP85_000793"
     CDS             complement(38629..39234)
                     /locus_tag="VYP85_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1881335.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39407..40444)
                     /locus_tag="VYP85_000794"
     CDS             complement(39407..40444)
                     /locus_tag="VYP85_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1881336.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40478..41413)
                     /locus_tag="VYP85_000795"
     CDS             complement(40478..41413)
                     /locus_tag="VYP85_000795"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1881337.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
BASE COUNT        12396 a         9113 c         7542 g        12737 t
ORIGIN      
        1 taccgtggga ctaaagttgt acaagaaaag tgcaaataag aaatctccag attaggaact
       61 atccgtgagt tctctagtct ggagattttt caatagactt cgttattgga cggttaccaa
      121 gttactcaaa gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa
      181 atgaaaatca aaaagcaaac taagaagcta gcctcaggct gtacttgagt acggtaaggc
      241 gacgctgacg tgatttgaag agattttcga agagtataaa acactgtttt gaggtggtgg
      301 ataaatcggc tgggtaaaaa ctcaatctca ggagaaaatg aagtaaatct ccccacaact
      361 atagaaaaag atttgattct gctcctcaca caataaaatc tttttctttt attaaaaacg
      421 aatcgtttca cgtgttttct catatgaggt aacaaagcga ttggttacac caggctctgc
      481 cacttccaat gcttgagaaa tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa
      541 aatatctaaa gcttcgttaa atgcttcttg aatgcgttca tcaaatgagc gatagcggtt
      601 agaatattgc aagagttgct ctgtcaaagt tgcatattgt acaatattat aagtttccgt
      661 ttctaaagct tccatatcat tcgttgcaat ttcaagaact cgggtaacag attcaatgtt
      721 aatcattttt tgttctaact caaccattaa atcctcggta ttattgcttg ccgtaaagaa
      781 taacttcaag aaagtttgtg gaatacctgg cagattgcgt ttttccatgt atcgcttgat
      841 agtatggaga cgattgacat aaacattggc cttttgacgt gcattaatat catctttctc
      901 aatttgtgtc aggcgctcac taactgaaat ttgctcatct tcaatatctt ttagttgagt
      961 ttgtaaatcc tcaagatttt cttcaagaac tgaataagct tgggttggtt cttcttgatt
     1021 cgaagttacc tcaacaatag ctgcctcaaa actctctaat tctgtctgaa tacgacgaac
     1081 atggcttgca gctgtctcag gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc
     1141 caataaagta ttattctctt tcatatgttg aaggtaagtt ggaagagttg caagtagatt
     1201 ttccactact ttctgagcag caatttctcg agtaaaaata tcatacaagg cattgatttc
     1261 ctcttgtgcc tgtccattct catattcggc attatccaat tccaactgac gaatattctc
     1321 ttggtttttc ttgaatgctt cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac
     1381 aaaatgataa ttagcatcaa ttagtttacg ataaccggct tccaaatcct gtaattgatc
     1441 tggcaattct gtagaaagcg tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa
     1501 ggccaaaatg tgattttctg tattatccaa aatcactgcg gcttccacag ggtcacccga
     1561 tgaattcaag gttacaaatt gtgaaaattc agattggata ttttctaatt gtttttcaat
     1621 ttcatccaag gcttgaccat actgttctga attttcagca actctatgct gaagttcctc
     1681 aaataaatcc aaagcatgaa gaacacgacc actattttta gattcttgct tctctaagtc
     1741 tgccaaagca ttgcgaattg ccgcaatatc ttcttcaatc aaagtaattt gactctcaat
     1801 ttggtcaatt tgatgactgg ccttgagaaa acgaaatgaa tggttatagc cttctgcttc
     1861 aaagagatta ttttcaatat cggcaaaaga gttgagagat aaatcgaccc atttttgatt
     1921 ccattcacgg aaagccactt gactttgtcc aatcaagtgc atatttttta cagcttctac
     1981 ttcatcattt actggaagat tgtatagttc ttcttttctt tcttctagcg cctctaatct
     2041 cccctcgttt cgcttacgta gaaagattgc cactacataa gccagaacta aaatgactgc
     2101 aattgcaacc attaaataaa ttagttgtcc attagacata tcaaactcct tttttacttg
     2161 aaacaatcgt aacgattata tcatattttt tagaccaagg gaactacttc tccctatttt
     2221 ttagacatca agtgtactat agacagcatt ttcttcgata aactcacgac gaggctctac
     2281 tcgatccccc atcaacatat caaagatttt atctgcttct gcagcatcat ctacagaaac
     2341 tctagccatc aagcgatgtt cgggatccat ggttgtttcc cacagctgat gatcgtccat
     2401 ttcacctagc cccttataac gctgaatagt cggtttggta cgaccttcac tataacgggc
     2461 taaagcttct tggagtttga tttcttgatc tgcacccggc tggatatatt ctttaatctc
     2521 gcttccaacc ttgacaccat agattggtgg ttgggcaata taaacataac cagcttctag
     2581 gattggtttc atataacgat aaatcaaggt taaaagaagg gtacgaatgt gggctccatc
     2641 gacatcggca tcggtcatca aaacgagttt ttggtaacgg gctttcgaaa catcaaattc
     2701 tgcgccaaat cctgttccca tggctgtgaa aagactacga atttcttcgt tagctagaat
     2761 cttatccata cttgcttttt caacgttcaa aatcttaccg cgaattggaa ggatagcctg
     2821 aaactcacgg ttacgaccag atttggctga tccaccagct gagtctcctt cgacgatgaa
     2881 gagttctgtt tcagcagggt tattagaaga acagtctgct agtttccctg gaaggttgga
     2941 aatttccaaa ccagattttt tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc
     3001 cttggcagct aaaatccctt tttccacgat acgtttggca atctgtggat tttccatgag
     3061 gaaatcggag aaggcttcac tgaagaggcg attggtaatc ttgaccactt cgctatttcc
     3121 caatttggtc ttggtttgtc cttcaaactg tggatttggg tgtttaactg agataactgc
     3181 agttaagcct tcgcgaacat cttcccctgt taggttgtct tcattgtctt tcagtaactt
     3241 atttttacga gcataatcat tgataacacg tgtcaaggct gtacggaaac cttgttcatg
     3301 cgttccacct tcatgtgtat gaatattatt ggcgaaactc atgacatttt catggtaacc
     3361 agttgtgtac tgcatggcta cctcaactgt gatatcatcc atctcaccgt ctgtatagat
     3421 tggtgtatca aagattacat ccttgttctc gttgatatat tcaacgtaac tagcaatccc
     3481 accttcataa tgataatgct tggtttgttc caaaccttca cgcttatctg taattgaaat
     3541 ttgaagaccg cgatttagaa aggccaactc ttgaatccgt ttatttaatt tatcaaaatc
     3601 aaagattgtt gtttcagtga agatttttgg gtccggtgtg aagtgaacag ttgttcctgt
     3661 tttatccgta tctccaacta tttcaagatc tgcgacaaca tgaccacgac ggtattcttg
     3721 gtaatgaatc ttaccatttt tgtgaacatg aacgtctaat tgagtggaaa gggcattaac
     3781 tactgacgac cccaccccgt gaagaccacc tgaaaccttg tatccaccac cgccgaactt
     3841 tcctccagcg tgaaggactg taaagacggt ctcaacagca ggacggcctg ttttttcctg
     3901 aatatcgact gggataccac gcccatcatc cacaacagta atcgaatcat ctggctcaat
     3961 aaaaacttga atatggctgg caaatcctgc caaggcctcg tcaattgagt tatcaacaat
     4021 ttcccagact agatggtgaa gaccttcttt tgaggttgat ccaatgtaca tccctggacg
     4081 catacgaaca gcctctaagc cctctaaaac ttgaatttga ctggcatcat aatcctgtgc
     4141 ctgcagattt ttgatttctt ctgtcatctt attccttttt cttatatgtc taatacttgt
     4201 cttaaattca cgatactggt aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg
     4261 atatcaatcg gccgatcacc aatgacaaga ccagagctaa tctgatactt ttctcttaaa
     4321 taaagcatgg attcgggatt tggctttctc ttaaagcctg agctagaagt caccacttct
     4381 gtaaaataag ctgctataga ggttttttct aaaatttcca aaacctgatc atttcgatga
     4441 gagaccaaaa aatgacggcc accttgattt gaaatgactt ccaataggtc agaaactcct
     4501 tcaaataaaa tcgggtgttc aagctctctg gcttcatttt ccttgtactt ttctaaaaaa
     4561 ttctctaaat tgggagcgaa tgtctcaatc gcaaaaggag tagaaacctt taaagcttga
     4621 tagacactgt catggtcttg tgtgatacca tacagtgcca atgtttcaac aaatgcagct
     4681 gttgaagttt cataattatc cagtaaagtt ccacctaaat cccagatgta atcgtgatat
     4741 ttcataccct tcattatagc atttttttat gaaaaaagcg atgatttccc tgagttttcc
     4801 acataaaaaa cgagagaata actcccgttt tactgatttt taccaaagac atcttgatag
     4861 agcattcctg ttcgtaaact ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca
     4921 aaggcaaggg ctgttgaagg accccgactg gttgtcaact gaccatctac cactactgtt
     4981 tccttgacat agtgaccatc aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc
     5041 ttatttttca atatctctgc ttgattgagg gcaattggtg ccgcacaaat ggctgctagt
     5101 ttcttccctt cttgctcgaa gctttgcaat tcttgaatca aggtctgatt atcacgtaaa
     5161 tgtgcagaac caggcatacc tccaggaaga acaatcatat catagtctga taaatctcca
     5221 tcaaagacat gatctgctct tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa
     5281 ccaaccatat cacatgtgat attggctcga cgcaagacat ctacaactgt caaggcttca
     5341 atttcttcaa agccctgagc taatataact gctactttta ccatgatttt ctccttattt
     5401 aatttgtttt aatacaacct ttttccgttt gaatggaact tttccgctct tttcttcagc
     5461 tagattagtc tggtaactca tcgataaaag caaaccaaca ccaatcagat tactgataat
     5521 agctgatccc ccttgcgaaa tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt
     5581 cacagcaccg atattctcaa agatgtggaa gagcaacatc ataatcaaac ctgtggaaat
     5641 ataagtgtag aactggttat ttgatttaag agtaatcttc aacatacggt aaatcaacat
     5701 gagatagagg gcaataacca ggacagagcc aataaagcca aaatcttctg caataaccgt
     5761 aaaaatcata tctgactctc gaactgggat aagcagattc gaagcattaa atccctgacc
     5821 aaataagcca ccactcccaa tggcaatctg cccttgagcc tgctggtaag tcgttgtttg
     5881 ggcaaactca aagggattga gccaagccaa aatccgattg atttggtagg tcggcattcc
     5941 aatctggtga agaaaagctc gtccgtcctt gctaataaag atagctaaga aaccagcaac
     6001 tcctgttaca gcagtcacaa atactgggat aataattttc caagaaaccc ctgataataa
     6061 aacgattcct gagaaaatgg ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc
     6121 taaaagaact aggactggaa tggtaaagag aatcatccag aaaattaaca aaaagtccag
     6181 cggaaccgtg cgtctccatt ccttatgttt ctttgtaaat tggacaatga cacgagccaa
     6241 catgaggata taggatatct tcataaattc tgacggttgg aatagggtaa ttccatttat
     6301 tgatacccag tttttggcac ccgttgatgc aactaagctt ggattataaa atacaatcgg
     6361 caagatcata agtcccaagc ctaaaatata tagaaagggg gtcaccttcc aaagaaattc
     6421 tgtattaaag agcatgacca caaaaccaat cacaagcccc aaggcaatcc aggcgacctg
     6481 ctgccctaaa atgggcagaa tattattggg gtaatcatga ctaacggcta tatagatagc
     6541 caccacaccg atgaccagta gaaaaaatac tggcaagagc aaactgtaat cgactcttga
     6601 gtcgagagaa cgtttcatat atactaacct tatactttca tacaatacta tttatcaaag
     6661 ttcattaaaa aatctatcaa tagcctcgtc aacttcggat cgagagatgg ttttaacagt
     6721 cgcttcttct gctagagatg ctactatttg tttgccgtat cgttttccga cgattctcct
     6781 atccaaaata agagttaagg aacgttgata ttcacgtctc atacttcttc ccaaagcctg
     6841 ttttaaacga ataatggcca ttggcaattg ataatcataa aaggcatttt tcccttcttg
     6901 attcagttct tgattaatct ttttcgtcaa gggttcttga ggattttgga aaggaagcct
     6961 cggtacaact tgaatcacaa aaggatggct tgaaaaatca actccctccc agaaacttgc
     7021 tgcaccaagc aagatttgtt gttcaccttt ttcaaagcgt ttctttagct gatgaacatc
     7081 cccattttta tactgggcca agtggctaac tgtaagtaaa tccgatactg ctagaagcat
     7141 gtctttagcg gtaaagagaa ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa
     7201 agcagctacc tctctggcat agacttctaa ggaggtttct gttaccagag ggaaatcttt
     7261 gaccatgacc acttcttgtt cctgttttcc ccgagattca atcttgacaa atttagcttc
     7321 aggatagcct aaaaggtctg ccaaagaaac cctctgacta atctcaagag tagccgatac
     7381 tcccaggact tggcaactct caggaagtaa agaggacaga agagtacggc ctgattttgt
     7441 agaagaaatc tgaattttct tttgactcgt ttcagttact tcaagccagt aatcaccttc
     7501 agctgtaaaa tagcgaacca gctcatcaaa gccttctact tctaattctg aaaaatactg
     7561 atggagatta tccagagaat ctaagatatt tttcctagat ttgccagact gaaattgttc
     7621 tatcaagtag agacactcaa agcgaatact ttctagtatc cgttgttgaa ccctgttttc
     7681 ttctcctact aaagccttat caattaaatc gataatagat tgtatatcgt aggtctcttg
     7741 aagcagattt tctagagcta acaaaatctt ttggacttca tcaataatca gtaaacggtc
     7801 actgacaaat tcaggattat cttcaagtct ggtcacgaga taggcatgat tagtcactaa
     7861 aagcttgcaa gtctctgccc tttcttgact acgtttccaa aaatcttccg tcacaaataa
     7921 gctatgggat gataaattcc catcatgacg aaggtctgct agaaaatgtt ggtaacggta
     7981 gagttgcccg atttcatcca aatctcctgt ctctgtctca gtaagccaga ccaagacttg
     8041 cattttaaag cgtctaaata agcgattttc atcattttcc tgcaaggaat gataaaaggc
     8101 atccaacttc agataatttt gtggtccctt taagctatga atatctgtat ggaacacttc
     8161 cttgagacgt ttaccttctt cttccatgat ttgattttga agaatctttg tcggaacact
     8221 aagaacaatt tgtcgctctt tggattgaga taaagcgggt aagagatagc cataggtttt
     8281 cccaatccct gtcggcgctt gaatcagaga gacaggttca tctttcaata gcaagccaac
     8341 ctctttagca aaactttctt gttcctccct cacttcaagg ttcaacagag aaatattttt
     8401 agaaaagtct tgagatagtt ttcgtagctc cagagaagct gccgttttct taaaatacag
     8461 accttgaact tggaccaagt ctggagaact caggatagat tggttgcgat aagtttcctc
     8521 aataaccagg taggactcat ataggagagc gtcagccatt tccagcaagc gttccaagag
     8581 acctttagga agctgggtca tcttttcccg taaaaaaaga agtaattctg ctgtagcttg
     8641 ggcatctgaa agggctgtgt gtgcgtgttt aagaggaatt cctaattctc gacacaaaat
     8701 cggcaagcta tatttttcca gttcagggaa aaagacctgg gccaattcga ccgtatcaac
     8761 acgagggttt cttagctcat agccttcaaa aaataaattt tccgccaaga gattagcatc
     8821 aaactgaaca ttatgggcta caaaaatccc atcctccacc aagtcaaaga tttttctggc
     8881 aacttgcgaa aaatcaggtg cttgcgccag acgttggtct gtcaatcctg tcagttcttt
     8941 gatatgagca tccaagggtt catgtggatt gacatccgtc gtatagtgat cgacgatttc
     9001 tccatcctca atcacgacaa ttcccacttg gataatttta gccttactac ctgtgctagt
     9061 tgcctctaaa tccaccacaa catagcgatt accaatcgtt ttcattataa aaaattatac
     9121 caaaaaaagg gccatttggc acctgcaaac ataggataat tttcaaactc aagaacacta
     9181 cttttcttag aaatcccatc gaatagagca ttctagcctg ctgatttttt taaaatagtg
     9241 aagaaatacg aaaaattgag agaagaaatg ttttcatctt ccttctctca acgaatcatg
     9301 tattttattt aaccatgtca ggatcgtagt cataaaatcc tgtatcaagg aaacggtttt
     9361 tagggtgaag tttacgaact tcttcatcca gcaagaaggc ttggtcatgg ctaaagttgc
     9421 cctcttgaat caagctacgc gcttggataa agagttttgc aatctcaaca aagttctgac
     9481 caggagtgta gagcccttct agtttccagc gagtaaagcc atgctccacc aattctgtta
     9541 atttgatcat caaatcaagg tcattgttgg caaagatatg ggtcccatga ttatcttcaa
     9601 aaatggaata gtggctctct ggatcacttg gctcagccaa gaagaggtca cgtttatgcg
     9661 tcttttcatc atcgatatgt gtaaagttat agtagttttg caagagtgga cgtttagaat
     9721 gatggatgac gctagcaccg taaaccaaaa cttcagcagg aatttccaaa atctctggca
     9781 ttttgaaaag ttcagctgat ggaatttcac gcgccaaaac agcctcagat gcgccagcct
     9841 tttgtcccca gaagttaatc tgacgactgc tagttaccat ggttgaagca tcgtagatgg
     9901 tcttaaatga ataaccatcg cggttaacta cgtaaaagac gcctgcatcc ccaatcgtaa
     9961 tatagtctgt cttgatttct tccaagaagt ctaagaaagg cttgatacgg tccatcatat
    10021 cttggtgcat gagagcattg accgcaacga gcaattcctt accagcatca tgaaccaact
    10081 tagcgatttc acgtaattgg tcataactaa aggtcgttgg cagacgaagg ccaaaatctt
    10141 tctcaccgac atagatacgg tctacgccag cttcgagtag ttgttcaact tgttcaatac
    10201 tttcagcagt tgctgtaatg acaatctttt ccataagaaa aattatacca catttctcca
    10261 aaatcatcca tgctttgaaa atgaaaaggg actttattct ttttgtaacc tttctgtaat
    10321 aattttctgc cgaaaaaatg ataaaatagg tatgtactgt taaggagaga atcatgcccg
    10381 taagaaaatt acaatcctat gaggtagact atcaagaaga attaaaccag cagcttcctc
    10441 attaccaagc ttatacacct gaagcgcaat ctgatgccaa tctcaaggaa atcctatttt
    10501 ttattaatat cgctgttttt tgtatctgta ttgctatctt tagttttatc tttttagcat
    10561 taaaattatc aactgctctt gcctttgccg cagcaatcgg attcagctta cttgttttaa
    10621 aagttcaacg gtctattatc aaacgaaaac gtagaagata aatccaaaat atcgccccag
    10681 ttggagcgat atttttattt tttcttttta gatggtgtct gaatggcaat cttcacttca
    10741 aagattgttc ccttgggttt attatctttg acagtaacag ttccttttag agcatctaca
    10801 atttgcttgg ctagggataa tcctaaacca aaaccacctt tttgccgggt tctagctttg
    10861 tctactcgat aaaaacggtc aaaaattttc tttttatctt ctgtcgaaat accgattcca
    10921 ttatcagaaa caagtaaata aagattgcga tcggtcgccg agataagaaa atcaatttca
    10981 ccatcctcct cagtatactt gacggcatta tcgaaaagaa tggtcatcag ttgtttcaga
    11041 agaagctgat ctgtgacaat tgttcgatgg atacgatttt caaaacggaa gacacgatta
    11101 ttttccgaag caatcatctc gtagtttgtg aaagttgtat taaaaaagct agttggaact
    11161 tctgcaagct ccggcttaat cccatcatct ctccgagcta agttcagcaa gcttgtcgtt
    11221 aaaaaacgca tatttcggac ttcttccaaa ctcgatgcaa tgctttcgct cacatccata
    11281 atggtagctt ctggcttacg aaaaagggtc tctaagcgat tttgcaaaac tgcgagtgga
    11341 gttcgtaact catgactggc attttccaca aaagactgtt gcttctgcat actctcaagc
    11401 aggggcctaa cactgaccct agctagatag agactggcaa gtaaagacaa aatccagaaa
    11461 ctagccatca cgaccacaat caattgctca tgcttttgac tagcctgctc caactgactg
    11521 gtattaatca agacagcagc atacttgata ttggttgaaa ccgaactaat attggtctcc
    11581 atcaaaatca cacgatagat ttcttcctgc ccatagctat taaaaacctg aatctggtag
    11641 atatgtccta gttctttctt ttctaactta atcttatcca agcccaaaaa tcgatttcca
    11701 gaaagaagtt gagtaaagtc tttatcaaag agaatgactt ccgtattgga actgacatta
    11761 ggttttattt ctactttact agcgtccgcc ctagcatttt ctaaatcttt aatctcttct
    11821 gttgccctat ttatagccag ctgaataact gcttgaggat tttcactcag tccatgaagc
    11881 ttatcgtcca ccgaagtata aagactcgaa tgcatgactt gtaaaataat cagagtcatt
    11941 gtagaaaaaa tcagggtgaa gacaccgaag ttgcggataa aataactaaa gtcatccgca
    12001 taccatgttt ttttaagttt actgaacatc ttttaaaaga tacccaacac tacgcaaggt
    12061 ttgcaaattc tctgcaaaag tggttccctt taatttctta cggacttttg aaacatagac
    12121 ttcgacaacc gaaatcgttg tatcactatc aaatccccat agacggtcaa aaatctgcgt
    12181 cttaggcaaa atcacatttt gattttgaag gaaataaact agtaaatcga actctttccc
    12241 cagcaattcg acaggagtat cttcaacttt aacggtattg gttgataaat taaccacgat
    12301 attcccataa gtcaaggtgt tttcattaaa cttccctgaa cgtttgagaa gggcctgaat
    12361 ccgcatttta agttcttcta ggtagaaagg tttggtcaga taatcatccg ctcccagttc
    12421 aaatccatgt cccttgtcat ccaaactttc ctttgcagtc ataatcagaa ctggtgtcgt
    12481 aattcccttt tcacgcaatt cttttaagac ttggaaacca tttttttctg gcaacatcaa
    12541 atccagcaaa atcaagtcat agacaccact ctcagcttcg tagagacctt cttctccatc
    12601 aaatacctgc ataacatccg caaaatcgtc taaaaagtca aatactgaat ttgacagacc
    12661 taggtcatcc tcaaccaata agatttttat catgagaaac tcctccttat taaaactatt
    12721 ataccaaatt tgccttaaaa aaaactcaac tctctgcatt ttacatgaga tagctgagtt
    12781 ttctttttat tttaggctta tttatgcatt tccgtattga agaacaactg cttcgactgc
    12841 agctttttca cggctaatca agtcaacacg cgctgcaatt tccttgattc ccataccgat
    12901 gttacggcta agagcaaggt cagaaagttg cggttcaaag aactccttgt attccgccaa
    12961 gcgttgctga gtcttaaata catgagcagg aaggataaca aagctatcaa agctcatatc
    13021 tcctccaagg gctgccttaa tccaagccca gttttcacgc gcccaagacc aagctgtttt
    13081 ctgagttgct tgatgagcta ggaattggta ataccaagca gacaagtcct gtggtttgac
    13141 cacaaatttg tccttccaag aagtaatcaa gttttggata ttatccgcat ctgtactgta
    13201 tgcaagagct gctgtcaact ggcgtttaaa gacagcatct gttgcgtgag tataagtatc
    13261 aagataaagt gctaacaagt ctttagtctc atgatgtttc atctcattaa tcagaacttg
    13321 tgaacgaata gctgctggga gttctgcaag attctccttg tgtgttgcga agatttggct
    13381 agtgacttga cgagcttctg catcatttga gcgaatcatc atcgaaacag ccagctgacg
    13441 aaccaattca tcctcatctg attctccgtc tttagcttca aaaccaagac ggtcatagtt
    13501 atgacgagcc aatttagcaa ccagtccttt gaaggctgtt tcagcatccg ttccttcatc
    13561 aataaagcgc tcaagggctg aaatcacttg agaaacagct gaaaccacca gataagactc
    13621 ttccttagca agtttatcaa gaactggaag caagtctgca taagaaatgt gccctgcctc
    13681 agccaacaaa cgacgttctt gaacaatttg cagtttgctt gtgttatcaa gtgtctctag
    13741 ctcagcaaga acagcttcta acaagtctcc ttgatagtcg gtaatatagt gggcagtatt
    13801 ttcagtgttg agacgaagag ctccttcatt ttcagcaaga agagctgcgt agccagggat
    13861 ttcgatactt tcagtttcga gtgtatcagg caagcctttc cagttgctat tgaggggcac
    13921 cacccagaga cggttcttgt cttcgttctc accgatgaag aattgttttt gtgaaatctt
    13981 caagacatca ttttcaactt tgacagtaag aactgggtaa ccaggctgtt ccaaccaaga
    14041 atccatgaag gctgcgacat cacgtcctga cgcttgacca agggcatccc aaaggtcact
    14101 accaatggtg ttgctgtatt ggtgtttttc aaagtaggca tgcaaacctt tagcaaaatc
    14161 agcatctcct agccaacggc gaagcatgtg catgagacgg cttcctttgg catagacgat
    14221 agcgccgtca aagagtgtat tgatttcatc tggatgttta acttcgacgt ggacagactg
    14281 aacgccatca gtagcgtcac gttcaagagc aagaggtact ccacctgttt ggaaatcttc
    14341 aaagatattc cagcttggtt cgatggtatc cacacagacg tattccatca tattagcgaa
    14401 actttcattg agccaaaggt catcccacca tttcatagtc acgaggttcc caaaccattg
    14461 gtgagccaat tcatgggcca caacaagggc aacttgttga cggctagcaa atgtagagtt
    14521 ctcatcgaca accaagtaaa cttcacggta ggtcacaaga ccccagtttt ccatagcacc
    14581 agctgagaag tcaggaaggg cgatgtggag agattgagga attggatact taactccata
    14641 gtaatcttcg taaaactcga tagagcgaac agcgatatcc agtgagaaat caagatttga
    14701 aagtggatgt gctttggttg agtagacacc taccagggta ccatttttag ttttagcggt
    14761 caccccttgc aaatcaccag caaaaaaggc caacaagtaa gaagacatgc gaggtgttgt
    14821 ctcaaacttc cagatacctg tttccttacg gttttcaaca tcgatttctg gcatgtttga
    14881 caaggccaat tcaccttctg cttggtcaaa gcgaagagag aggtcaaaag ttgctttggc
    14941 ttcaggctca tccacacatg ggaaagcttc gcgcgcaaaa tggctctcga actgagtaga
    15001 caagacctcc ttcttgactc catcaactgt ataataagaa gggtaaatcc ctgtcatgtt
    15061 gtctgtaatt ttaccagaaa aggcaagaac caattcaact tgaccagcct cagccaattc
    15121 gatatgaagg gcttcattgt catggtcaac tgtaaatgga cgagcttgac ctgcaacttc
    15181 tacagaggtg atttccaagt ctttttggtg gagggagatg cggtcactct gtgcttgacc
    15241 agtgatggtc actttcccag aaaaagtctt ggtctcacga ctcaaatcta aaaataaatc
    15301 ataatgttca ggaacaaatt gcttaataaa atgttcaact gcttgcatag ttttctccta
    15361 ttctaagttt aagagctgct gctcttcttc aaacaaactt attatatcat attttgcttg
    15421 aaaaaaaagg attggacagc gatttccaaa actttcttcc ttctaatagt ctacagtggg
    15481 tagaccttgc gaaattcttc taaaacaacc ttgctttcag atgtaaaagt cagccctact
    15541 tcacccaaac agtctgtgaa aaagtcctca tgaacctggc gccaataggc aagtgatttg
    15601 tctccctcac cttccttaaa ggcatgttgc gcagaaactt gattgaagag ttcaacagaa
    15661 acctttgtaa tttcgacaat gcagacagac tgattttgac tatctaaaat gatatcgaag
    15721 gtccctactt ggggaagtgg ttcgtcttct agtacataga ggtcataggc tgatgctgtt
    15781 gctgtctttt ctcctttaaa caccaaatcc gctaaaaggt ctggttcaac tccaaaagcc
    15841 caagcatcga tttcatctcc gatcaaagga ttgatttgct tgtatttatt ccacatttct
    15901 tgcggtatca tgggtactcc tttgtaattt tttactttct tcttttatgt gtttaagatg
    15961 atctggatgg tcaatctcta aatcaaaaat ctctggaata gaactgtagt ggataatgca
    16021 cttgataccc aactgattca ttttttgtat gaaagaagta ttcagatagc ctgctacagc
    16081 aaaatcaatc ttgttctttc ttgctttatc ctgcatatct cttagcatat ctaacattat
    16141 tggactttcc atatcatgcc attgactgtt tctcatagtc gcaaaaacaa aggaagtcaa
    16201 atcattcatt ccaactacaa tctttgaaat gcccgtttcc agtatactag ataagtcaaa
    16261 atacgctgac ggtaattcaa tcatcgttcc gactttccca gtaaaaccct gctgacgcaa
    16321 tactgtaata gcttgtttta attggtcgtc atcattgaca aaaggaaaga taacagatag
    16381 attggggttg gtttgataaa cttctgtaac gacatgtgct tcagcctgaa attcatccaa
    16441 acacgccagt aaacgcctgg ttcctctata gccaaacaag ggatgccctt cgtcaaaaaa
    16501 ctctctagtc cccactaaac aattggcttc tgtattcgtt aattcagaaa aacgatacca
    16561 aacttcttca tctgagtaca gggagcagat agtctctaga taatctttta caaattgctg
    16621 acaacttgct aatatgatgt tttgattaag ctctctcaac aaatattccc cacgaatcat
    16681 gccgacgtgg tgaaatagtt gaggataaat tttttcaaga attttttcgc cactaagggc
    16741 aagttgattt ctcatcattc accttccaat tcatgtaaga agtcttgtcc agttctggaa
    16801 atcctaataa ttcagactta accttcaaga ctaatggcga tgcattttct tctgtaattt
    16861 cttgaatatc catccaaata tatccaagtg aatcattcgc accatcagac acagcttccg
    16921 aagtcgtaac ttgaggtgca ctctcattca tttcaacatc atacaaggcc atgacatggt
    16981 gaaccataaa attttttaac tcttctctga cgaaaacatc gtagattcga ggattagagt
    17041 agcttctaac agtaaatctc gtctcttcca taacttctct agtcagcgtt tccgtcagtc
    17101 cttcaccaag ttgctgactg cctccaggta gatcataccg atgttgataa gggcctctcg
    17161 ttttttcaat gcaaagtaac tttccatttt caaagcaaac acagtagacc ccaaagtgtt
    17221 ttttgatttc catccaactc ctcctacttc aaagaccagc caccatctat tgtcaagatt
    17281 tgtccttgca tggcgctcgc ttttccactt gctaaaaaaa gactaagctc tgctatttcc
    17341 tctggctcaa tccagcgctt gattggggtt tcactagcca cccagtcagc caaaccacct
    17401 ggttcaaaat ccgcagcggt catagctgtc ttgactgctc ctggagcgat accaaagacc
    17461 tgaatcccag cttcagcata gtctagagcc aactgcttgg tgaagccagc caaggcatgc
    17521 ttggatgaag tataggcgtg accacctcca cctgctaggc tagaagcaat ggaacacata
    17581 ttgatgatga ttcccttttt attttccagc atttgtgtca aataataccg agtcaactct
    17641 actggaataa tgtagttgat ttcaaaaatc tcttgaatgt cctgcgccgt ttgttccaac
    17701 agtggtttgt aatcatccaa aactccggca gtattacaca aaacatccac ctgagggcac
    17761 cagtcaaaaa taggttccaa gtccaaggtc aaatctctct gtaaaaagtg aaaatcaccc
    17821 tctaagagtg gcttttcacc ttggtcaact ccataaactt gatagccctt ctctaaaaag
    17881 aggcgagctt gagccaatcc gatccctgaa ctcactcctg taatgagtac acgtttagtc
    17941 atgcacttct acccaatccg ttgccaaaac atcacaagct gtcgggctcc acatggaaaa
    18001 accttctcct tctccagaca cgttgattag gaaataaggt gtcacttcaa gtgcaagccc
    18061 attttgctcg atggtatcaa agagttggac atagttttcc gcacctcccc aaccagttcg
    18121 tacatatttt ttcttagcct ttaagccagg taaaatttct tcaaatgtca tgtttttctc
    18181 ctttaatgtc aataattctc cccttcatta taacaaaaaa accgctttaa aacggctttt
    18241 tgactgtgat ttattcaaac ctgctactac ttacggcaaa ttattccctg cagcaagata
    18301 aatttcatac cattcttttc ttgttaagct aaagtttgcc gctcggctaa cttctctcaa
    18361 gtgcttagga tttgttgtac ctacgactgc ctgcattttt gctggataac gcaatatcca
    18421 agaaatggca atagttgaag aggttactcc atatttaata gctaaacgat caagtacttg
    18481 atttaaagct tgaaatttct catttccaac aaagttccct ttaaaatacc cgaattgcaa
    18541 gacagaccat gcttgaatga ccacatcgtg taatttgcaa tattcaaaaa tgctgccatc
    18601 tcgcatagct gcttgactat cttccatatt aacatgaaaa gctgattcaa atcctggagt
    18661 aaaagccgca ctcaattgta gctgattaac agctaacggc tgcttgacat cttttttaag
    18721 caactccatc atcataggat tttgattaga aactccaaaa tctcgaactt taccttgttt
    18781 ataaaggaga tcaaaggctt ctgctacttg gtcagattcc atcaaagcat ctggtcgatg
    18841 aaggagcaag ctatctagat gatcaatctt caatctttgc aaaataccgt ctactgattt
    18901 tataatatag tccttagaaa aatcaaaata ggtaaattct tcaatgcgaa tgccacattt
    18961 ggactgaatc cacatctttt ctcttaaatc tggacgattt tttaggacaa gacctaacag
    19021 ttcttcacaa cgaccacgac cataaatatc agccaagtcg aaggcattga ttccaacaga
    19081 aagtgctgtt tctacaagct cttcaacttc ttttacagac ttatctttta ttctcatcat
    19141 tccgagaaca atttctgata attctttgtc atcttgacca agagttatgt atctcatcaa
    19201 atttttctcc tttaatttct aacattcttc ccttcattat aacaaaaaac cgctttgcaa
    19261 cggctttttg actatacttc actccatttt atcttcttaa acccacggaa caagacaaag
    19321 attccaataa agaggacagc taaaggaata acttttgtaa ggaaaacatt tgaaattccc
    19381 atccactcat aataacggag cagagaaccc accacaagat gggcaataat catactgaca
    19441 aatggacgaa agaccgcttc tttccaattc caaataccga taactagcga aatcgtaaag
    19501 acagacaaac tatcccaggg agccggaata taaaaggctc cttcttgtat gaagcttgcc
    19561 attcctacat atcctaaaac aactagaaga actatagtcc caacaacaat gtaagtgcca
    19621 attttcattt taggagaatc ttggactaaa cttcttcgta aaattgtggc cacaagtcca
    19681 aatccaatca gaaaaataag aagttgccct aaaaatgtga gcaaattgac tgttaagaga
    19741 ggacctttag aaaaatcact tagtagttga taataacgta ataccgccag gacaagaatt
    19801 ggcgtcaaaa gggactcttt gatagaactg cgaggtgctc ccttgagaat ctctttcatt
    19861 atttttttag gattcttacc tagataatcc tctgcactca tgccatctcg ttctgcttct
    19921 gagaaatcta gcatcatcaa atagatctgc tctctgagat agtcttcatc atagagaaat
    19981 ccagcaagat taaaactttc ccacaactcc tcaaaatact tttgattctc ctcagaaaac
    20041 tcatgtagca aagcgcttgt ttcttcgtaa tacttcattt tcttcatggt ttaaccccca
    20101 ttcttaatcc cttctacttt ttgactcaaa tcgtcccatt gttgccaaaa gactgagaca
    20161 cgctcttctc cttctttcat taatgaaaaa tacttccgat ctggaccatc tggcgacggg
    20221 cgcatgtcgc ctcttatcca ttgatttttt tctaactttt gcaacaaagg ataaatagtt
    20281 cctggaacga tagtatcaaa tccagcctct cgcaaagtct gaaccaactc ataaccatac
    20341 cgctcttttt gaccaatcat atccaagaca caaccttcaa gaacaccttt taatagctga
    20401 gtttctttca tcacttctcc cttctaatct attttgtaat acctactagt aacttcacct
    20461 atagtatatc acttctacac tagtttgtaa agcataatag ttaatactct tcgaaaatct
    20521 cttcaaacca cgtcagcgtc gccctaccgt atgtagggtt actgacttcg tcagtttcat
    20581 ctacaacctc aaaactgtgt tttgagctga cttcgtcagt ttcatctaca acctcaaaac
    20641 tgtgttttga gctgacttcg tcagtttcat ctacaacctc aaaactgtgt tttgagcaac
    20701 ctgcggctag cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa
    20761 ctagcctgaa ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga
    20821 tcaactgtga gaagggttaa tttgccatca tgttcagctg agagaatcat accctggctg
    20881 acatattttt tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg
    20941 accaattctt gttcatttgg atagtatttg gcaattcctg aaagaatctg acgatcttct
    21001 ccatcaccag catccaagca gaattgaagc aacttatctg aaccttctac tttagacact
    21061 tctttgactt ctgccacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc
    21121 ttgtttagtt tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg
    21181 ccttccattt gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata
    21241 ggtgttcctt tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca
    21301 agactagaaa cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata
    21361 aatggttcaa tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt
    21421 gccaattggt cacgaagagc ttcatccttg gccaagaccc atggtgcggt ctcatcgatg
    21481 tatttattgg tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact
    21541 gcttccatgt gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga
    21601 tcaaattcag tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc
    21661 atggaaaccg tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg
    21721 ccaacatagt cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg
    21781 tagtaacgaa gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc
    21841 ccttttgact tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga
    21901 tcaggtaatt taacatccaa catcataaga aggattggcc agtagataga gtggaagcga
    21961 aggatatctt ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca
    22021 tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg
    22081 tagacaacgt gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat
    22141 accgccaaat cttccaaacc tggctcgatg aagttgcgta gcatttcatt aaggcgacca
    22201 tctggcgtga taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg
    22261 ctaaggcgaa gaaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca
    22321 ataccaccag tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta
    22381 aagaattctt cgtctgatac tgaataccaa ccagagtatt cacccaagta aatatcatct
    22441 tgagcaagta agcgttcaaa gacctgtgcg acaacttttt catggtagtc atcagttgta
    22501 cggataaatt tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc
    22561 attccatcaa cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc
    22621 tgaccatgtt catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa
    22681 cgtgctagga catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat
    22741 ggatagtaaa tcggcgttgt aatataaaaa tttttttcag acataatttt tcctttccag
    22801 gcaaatgaaa cctgtttttc taacacttca ttatatcaca tttttaatga atttcgatag
    22861 ggaaatccat acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga
    22921 agggcttcaa ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata
    22981 ccaacactag ccgaaactgc aagactaaat agggcaactg ggattgatac tccaacttct
    23041 ataccttcta ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt
    23101 gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt
    23161 aaaatattgg cacgtgttgc acccaaagcc ttacgaagac caatctcacg agtgcgctct
    23221 gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct
    23281 gcgatggaac taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca
    23341 acggactcat ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt
    23401 cgtgccagtt ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata
    23461 ttagctattt catctacatt aaaattcgca gcaagggaga tattggtagt aataggcaag
    23521 ccaccaaacc catatatttt tgatctttta gcctccggac tagtataaac cccaatgacc
    23581 cggtaactaa atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat
    23641 aaactaatgg acaattcctc atctagcaaa atgacacttg caaactcttt gaaatcttgc
    23701 tctctcagac tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt
    23761 ccacctgtca aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt
    23821 gaattggtta catagtaact atccactccc ttcagtttag ctgcctcttg gacccaggat
    23881 tcttgcggtt ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct
    23941 gattgtttct gagtaaaaga cccatcttta ctttttttag gagagaaaaa gacgctaata
    24001 tttttctgag atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc
    24061 ataatcacaa caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc
    24121 atcttgtgag ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc
    24181 ctttcctaac tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt
    24241 ggcataggca gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt
    24301 caaatcaacc aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg
    24361 ttcatccgct aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg
    24421 cttttgacca ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt
    24481 gtctaaatat tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa
    24541 gggcaattct acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac
    24601 aaaaccgatt tgttggttac ggaccttagc tagttgtttt tcaccaagcc cagccacttc
    24661 ttgaccttca agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat
    24721 cagagtggac ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac
    24781 ttctagattg atatttttga gaacctgcag ttcttggtca ccattacggt aacttctgaa
    24841 gatatttttt agactaatta gttgcttcat cagccttcac ctcttttcct tcttccaagg
    24901 aagatgttgg attactgatg accttagcac cgttcgttaa accagaagtg atttcttgat
    24961 tttctgcgtc agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca
    25021 caatccagac ataattttta ctatcatcca ttactagact gctaacagga acaagaatag
    25081 ccttagtttt gcttttaacc tcaatgttga cagaaaaacc ttgtttcaaa tcaccaacct
    25141 cgcctgtcac atcaatagta taagggtatt tagaacctgt attattcccg gctgctggac
    25201 tagctgcttc accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt
    25261 ttttatcagg atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta
    25321 gattgtactc agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca
    25381 taacttgact cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc
    25441 cctctagggt actgagaaca gttgttgcat ccaattgact ttgagccttg cttaattgcg
    25501 ctgcagcatc tgcacgcgca tcacgggcat cacccaattg agcatcaata gaagcaacag
    25561 aatttccagc cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg
    25621 gtaactgtgg agcctgagct gaagcggctt catttcgtgc ttgattgagt tcattgatat
    25681 gacgatctgc cttagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac
    25741 tactgtactt gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt
    25801 catctaaatc acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg
    25861 tccctgacaa taaaacagag gatgccacgc ttccttcatt ggcaacaaca agatgagtag
    25921 gctcatcttt tagagcagtc tgagaaggtt gtctaaagag taaaatcccc ccggcaccca
    25981 atacaactac actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat
    26041 tctttttctt cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat
    26101 ttccctccag caaacaatgc agttcagatg gaaataatgg cagttcagga ttaaacaatc
    26161 gttcggaatt ttgcttttct attgtactag atatataata cactatcttg acttatttgg
    26221 caagcttttt tgcaattttt tgtgcgtagc agatttttgc aatcaaatca aaaaaagaat
    26281 aaaatataac tatcaaaaaa gacactctac tatttaaaag attacaaagg agttttcaat
    26341 gagagaatat gatatcattg ctatcggtgg aggtagcgga ggaatcgcta ccatgaaccg
    26401 tgctggtgaa catggagcca aagcagccgt tattgaggaa aagaaattag gtggaacctg
    26461 tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac ggggcgcaaa tcgctgagac
    26521 tttccatcaa tttggagaag actacggctt taagactact gatcttaact ttaactttgc
    26581 aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct cgttcttctt atgatggtag
    26641 ttttaaacgc aacggtgtag acttgattga aggtcatgct gaatttgtag attctcatac
    26701 tgtaagcgta aatggtgaac tgattcgtgc taaacatatc gtgattgcta caggtgccca
    26761 tccaagtatt cctaatattc ctggtgctga gctaggtggc tcttctgatg atgtatttgc
    26821 ctgggaagaa cttccagagt cagttgccat tctaggcgct ggttatatcg ccgttgaatt
    26881 agctggcgta ctccacactt ttggtgtcaa gacagatctc tttgttcgcc gcgatcgtcc
    26941 tttacgtggt tttgattcct acatcgttga aggtttggtc aaggaaatgg aaagaacaaa
    27001 cttaccactt cacactcaca aagtccctgt caagttagaa aaaactactg acggcattac
    27061 cattcatttc gaagatggta ctagtcacac agctagccaa gttatctggg ctacaggccg
    27121 ccgtccaaac gttaagggct tgcaacttga aaaagctgga gtgactctga acgaacgtgg
    27181 ctttatccaa gtggatgaat accaaaatac tgttgttgag ggaatctatg ctctaggtga
    27241 tgtaacgggc gagaaagaac tgactccagt tgcaatcaag gccggacgta ccctatctga
    27301 acgtctcttt aacggaaaaa ctactgcaaa aatggattac tcaactattc caactgttgt
    27361 cttttcacac cctgctatcg gaactgttgg tttgacagaa gagcaagcta ttaaagaata
    27421 cggtcaagac caaatcaagg tttacaaatc aagctttgca tctatgtact ctgcttgcac
    27481 tcgcaaccgt caagaatccc gtttcaaact cataacagct ggttcagaag aaaaagttgt
    27541 cggacttcat ggaattggct acggcgttga tgaaatgatt cagggatttg ccgttgctat
    27601 caaaatggga gcaaccaagg ctgactttga cgcaactgta gcgattcacc caacttcatc
    27661 tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag ctgatataaa tatgtctgct
    27721 tcttttttaa tgattttcga atcaacaaaa aattatccaa cttgactagt cacgaaaatc
    27781 ggctgttaca gtttttgtta ccttgttttt aaaaaatggt tgacatcgac tcctatatga
    27841 gtataatagt tactatacat tagaaaagag gttaactatt ttgaaaaaag ctcacgttta
    27901 tgctatccct gctattgggg ctgctctcat tgctgttttg gcacaaatca gtcttccaat
    27961 tggacctgtt cccttcactc tgcaaaactt tgcaatcggc ttgattgcta ctgtctttag
    28021 accgagagag gctgtacttt ctgctggact ctatcttctt ctaggtgcta tcggtcttcc
    28081 tgtctttgca ggaggtggag ctggttttca ggctttagtt ggccctactg caggctatct
    28141 ttggttttat ctcgtttact ctggacttac ttcctctcta accaacagca agagtggtgt
    28201 tgttaagatt tttcttgcaa acctcttggg tgatgccctt gtctttgtcg gcgggattct
    28261 cagcttgcat ttcctagctg gaatggcatt tgaaaaagct cttgttgtgg gggttcttcc
    28321 ctttatcatt ccagaccttg gcaaacttct ggctattagt tttattagcc gtcccctact
    28381 tcaacgcctt aaaaatcaga cttactttac taactaaaaa aggataccga gttatcatga
    28441 ctcaatatcc ttttttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta
    28501 ggaagctagc cgcaggctgc tcaaaacact gttttgaggt tgtagatgaa actgacgaag
    28561 tcagtaacca tacatacggc aaggcaaagc tgatgcggtt tgaagagatt ttcgaagagt
    28621 attagttgcc tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc
    28681 ctttgcccat tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac
    28741 cattaaagct cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca
    28801 acaagtgctc ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca
    28861 ttagtttatt cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa
    28921 gaagggaggc caatatgaga cataaattcc agcaagttct agataaaata catgattttt
    28981 taaatggaca tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag
    29041 aggctatcca gaaacaaacc gctgttcacc ttatcttgtc tgagacaagc tttacaggtg
    29101 atatcatcaa atatgatcag caaggccagc aaattatcgt gaaaaatttt tccaaaaatg
    29161 tgagccggat tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc
    29221 aaacagccca aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt
    29281 tttcttagcg aatttgttca aaatgtaaat gaactgcgat atgatctcca taaccacttc
    29341 tttccaagtc acgttgtaaa cgataggaaa tatagtgttc tgcaatggta atgtaacctg
    29401 cgcccaataa acgatgttca accatagatt gaatcatact gatagtcgca cgttccacct
    29461 tggcttcttg taaatccaaa actaccttct tagtgacttg agcaagattt tgacgcaaat
    29521 catctgtcaa aacataaaca gtttgggctg ccttcaagat ggcttggtaa atcttatctg
    29581 gattaaattc agcaatttcg ccattacgtt tgattacttg cataggtttc tcctttattc
    29641 tttgttttct ttgatttctg ccagcatttt ttcttcttct actgtcagtt gataatgttc
    29701 aagtaaatcc ggtctgcgct cgtaggtttt ctttaaactc tcgtacaatc gccactgacg
    29761 aatcttttca tgatggccac tcatcaatac atctggcacg accatgcctc gataatcata
    29821 gggacgtgtg tactgaggat attctaaaag acctgaagaa aaactatcat cttggtggct
    29881 agactccttg ccaatcactt ctggaatcag gcgaactgta gcatcaatca tggtcatagc
    29941 tgccaattct ccaccagtga ggacatagtc gcccagggaa atctcatctg ttaccaaggt
    30001 cttaatgcgc tcatcataac cctcatagtg cccacagata aagattagct cttcctcttg
    30061 agccaaatct tcagcataag cctgatcaaa ctgctttcca gcaggatcga ggagaataac
    30121 gcgcggattt ttcttttcaa tagcatcaaa ggaatcgaaa ataggttgtg ctctgagcaa
    30181 catgccctga ccgcctccgt agggctcatc atctacatga cgggcctttt cagcattttc
    30241 tcgaaaatta tgatactgga tatccaagag ccctttttct cgagcctttc caacgattga
    30301 gtgctccagt ggagaaaaca tctctggaaa gagggttaaa atatcaatct tcatcgtcta
    30361 acccttctaa gatttccaca tcgacccgtt tatttggaat atcaacattg agaaccactg
    30421 gtgggatata aggtaaaagc aaatcacgtt tgccttttcg tttgaccacc cagacatcat
    30481 tagcacctgg ttgcaggatt tccttgatgg ttccaaccaa gctatcaccc tcatagactt
    30541 ccaaaccgat aatctcgtga tagtaaaatt caccatcgtc taggtcattc aaatcttcct
    30601 cagcgacctt gagactgtat cccttgtact tttcgatagt attgatatgg tacatatctt
    30661 tgaatttaat aatgtcaaag ttcttctgtt tacggtggct agcgatggtc actgtttgga
    30721 caaactgatc tttttcatca aacaaagcca gctcagctcc ttttttaaac cgttcttctg
    30781 caaaatccgt cacagacaag actcgcatct caccctgtaa tccctgcgta ttaacgattt
    30841 tcccaacatt aaagtagttc atcttgtctc ctgtaatctc cttttttcca tcttattctg
    30901 acaattctcg aataatagcc gcaatttttt ccgattctga ccattgtaaa taatggtgat
    30961 tccctcctaa aatgagttta gtattggaag tccaatattc tgattctctg tactcttttt
    31021 ctctataagt ctgacaaaaa ataaatatag ggacatgaga ttctatcgac aaattctcaa
    31081 aatcttcctc agtaatctct ccagatatct gaaattctgg atcttgattt tccaactcta
    31141 agcctttttc ttgcattaat tcccagattt ttttattcgt ttcaggacta aatgttgctt
    31201 gagttaagtt cttaaaataa agttcaggac cacactcgtc aatcagcctc atctgctctt
    31261 ccatttctgg ataaggattt tctgaaaaat cagcaaacat gactttttta gttgtcggtt
    31321 caattgctac taaagtctga cacttaattg gtttctcgag taatttgcaa gctaaaattc
    31381 cactccaact atgtacacaa agtatatatt cagaaatccc taattcttca agtgcttcat
    31441 aaaccacatc tgcaagatta tctagatttt ttccagcttg gtcataaatc ggactcctac
    31501 ctgtgttcgg aaaatcaatt gtcaaataac caattgtagg aggaggtttt tcaagtataa
    31561 gtgaaaaatt ttcataactt ggtagcaaac ctgctccatt tagacaaact agcactttct
    31621 tttgcttttg ataagcaaca gagagactac caatttctgt agatacttca aacctcttca
    31681 taaagaaatc cactgattct atataatgaa ttattaaaaa tccttatcct ttattttatc
    31741 acgttccaag gattttctca agttggagga aggggacaac atctctactt tcccttcaag
    31801 aatccttcca aatcatgttt atgttggtaa ttaacggctg cggttttgtc tttctcaaag
    31861 atggttctag ttaggtcaat atgcttgata gcagcaatag cgacggtgta gagaatgata
    31921 tcagccagtt ctctggcaag ttcctcgttc gaatcctatc ccttcttttc gaccagagcg
    31981 cctattcaaa acctcggcta cttctccgac ttcctccact aacttcataa agagaccttc
    32041 atcagtccga gactgctgtt aatgttcgag taagtagtct tggaattgcc taaacgttca
    32101 atcttttata gtatattgaa actagaatag tacaccttta cttctaaaac attgttagaa
    32161 atcgatttga ctgtcctgat cgatttgtcc tgttattatt tcattttact atatcttcta
    32221 ttccacacaa aaaagcgaga catccgtccc gcccttctta tttttcgtca ataacgattc
    32281 ttactttttt gtattcagtt gggacagagt agacaatcgt tcttatcgca gaaatagtgc
    32341 gacccttacg accgattaca cgacccacat cgctttgatc aagattcaaa tgatattcca
    32401 aaaattctgg tgtatcctca atcttgatag ttaaggcatc tggttgtgaa attaagggtt
    32461 tcacaatcgc aataatgaga ttttcaatcg tatccatctg tcaacctact ttaaacttat
    32521 tttgaaaatt tagaatcgtg gaattttttc aatacgcctt cttttgaaag gatgttacgt
    32581 actgtgtctg aaggttgagc tccattagcc aaccatgtaa gaacgcggtc ttctttcaaa
    32641 gttacttggt tttcagcaac aagtgggttg taagttccaa ctgtttcgat gaaacgtccg
    32701 tcacgtggtg aacgtgaatc tgctacgttg atacggtaga aaggtttttt cttagaaccc
    32761 atacgagtca aacggatttt aactgccatt tttaaagtct catttcttta attttttatt
    32821 tcggtgaaat agctgagcta tttagcacat gttctattat agcagatttc tggcaggtgt
    32881 caagaaaaaa acttgacaga ctataaattt cttaaagcat ttaaaaattt gttagaatag
    32941 gaaataaatg tttgaaagat gctatccgtg aatactattt tagaaaaatt ttataaagaa
    33001 caccaagtca aacccttcat atcgcctgaa cgagatttgg atacttggct tctaagtccc
    33061 aagcccgttc ccaagcgaaa tatggactta ttagtagatg attcactagc aggagatatc
    33121 attttactat ggagaatcca gtttggtact tttaccactg aaacatgatt ttaaaaactc
    33181 ccattcgaat atgattcaaa attcgcttag aatcaatgtt ttcccacttt ttcaaaaaat
    33241 aaattttcat ctaatttaaa taactttcaa ttaagtgtga attttgctta aaatcattaa
    33301 aaaacacccc atggtgtgaa ccatgaagtg ttgtaaatgc tgtgttgtag ctagttctta
    33361 gcgtttagag aactggctag ctttacgagc tttcttaaga tctggtttcc aaaatacttt
    33421 gagtacactt atggtattga tgcccctaaa catctaaaaa ctctggtaga aaaagggtat
    33481 gctcttgtcg aaacttcttt tgactcactt gaccatctaa ataataccat gaaaaagaat
    33541 atcctgaaga agaagggagt tactggactt tctaaaatga aatcttgcga cctggatcaa
    33601 gcccttcatg agtatttttc agaagaagaa ttagctggtc actttcatgt ccttctatgg
    33661 acttttttac aatggcattg ctatcacacc caatacctat ctaagcgcct ggttcgtaaa
    33721 ctttattgca gctcttcctc taaatttcct aattgttgaa ccaattgccc gttttatact
    33781 aagttctttt cagaaaccat ttactgggga agaagttgaa gaagttgaag atttttaaga
    33841 tgatgatgaa atcccaacta ttatctaagc cagttctgta aactactaat atttgaaatc
    33901 cacttccttt tagggtacaa tggttataaa tgaatttttg agaggaacag aatgaaaaaa
    33961 ctagcaaccc ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc
    34021 agtctgcgtg gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta
    34081 gctgcccaat ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca
    34141 caactatcta aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt
    34201 gatattcgca ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact
    34261 cacgccaaag aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg
    34321 gtccaaactg gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag
    34381 gataagacta aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac
    34441 atccgcggtg ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc
    34501 ttcatcaacc aaaactctac agatacctct tctaaactcc ctacaagcaa gtatccacag
    34561 aaaattatcg aagcctacaa agaaggtgga aaccctagtc tagatggcaa acatccagtc
    34621 tttggtcaag tgattggcgg tatggatgtt gtggataaga ttgctaaagc cgaaaaagat
    34681 gaaaaagaca agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac
    34741 gattttaaat cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt
    34801 actctcattc ttaagttaaa ttattaaaat cccatatttg gtctatccaa ccttcataaa
    34861 agtctggatc gtggcagacc ataaggatag atcccctgta ttctttgaga gcgcgtttga
    34921 gctcatcctt tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt
    34981 tttcacgatt catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt
    35041 gaatctggct ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt
    35101 ctgcttgatt aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac
    35161 cgccttctac ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc
    35221 cagcgattgg cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat
    35281 tagcaccaat aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa
    35341 gaggacggtc gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac
    35401 gagctggttt gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca
    35461 tcttatccaa tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat
    35521 tacgagccac aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct
    35581 ctagctgaga tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac
    35641 gcgtcagctg ttgattttcc acatgataga caatattaat aacgtcattg aggaatggaa
    35701 tatcgtgcga aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat
    35761 caatatgctc agcatccaag tagttggtcg gctcgtccaa cagcaaaata tcaggctttt
    35821 caaggagaag ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat
    35881 ccgtatccat gccaaagtcc ataataccaa gagcacgcgc tacttcgtca atcttagcat
    35941 ccaaggtata gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga
    36001 gagcatcaac atccgcgccg tcttcagcca ttttcatata gaggtcattg atacgagctt
    36061 cagctttgaa aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag
    36121 caaggacaga gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc
    36181 cttcatctgg cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat
    36241 tggcaccgac caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa
    36301 ttgcacggtc accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc
    36361 cttaccttgt ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg
    36421 ttggtccaca aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt
    36481 aattgcgtac actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt
    36541 ttccgcaaat ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca
    36601 ttgaggatat tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt
    36661 ttccagagag aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatacct
    36721 ggagttccca ctcccacggt agattgttct tgaggagtaa agcaaaaaca gacaatgcaa
    36781 atgctataga aaatgactcc ccagaccaaa atatgattat aagtcttctt caccattaag
    36841 gatttaccgc tgcgactgcc ttctggcggt cacgtttcat tgtgttagag cgcaattgtc
    36901 cacaagctgc gtcaatatct gtaccatgct cttgacgaac cacacagttg accccttttt
    36961 tcttaagcgt atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat
    37021 gctcactaac tgggttataa ggaatcaagt ttacataaga caatttcttg atgttcttga
    37081 gcaattcagt caattccaag gcttgttcta caccgtcgtt gacttcatta agcatgatat
    37141 attcaaaggt tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt
    37201 tttcaatcgg aaaggcacgg ttaatcttca tgatacttga acgaagttca ttgttaggtg
    37261 cgtgaagaga cacggcaaga ttgacctgaa ccccttcatc agcaaagtca cgaattttat
    37321 gagccaaacc tgaggttgaa accgtgatgt gacgagcacc gatagccatt cctttatcat
    37381 cattgatagt acgaaagaaa ttcaagacat tgttgtaatt atcaaagggc tcaccgattc
    37441 ccatgacaac gatatggctg acgcgttcat cctgaccacg ctcatcaaag tatttctgaa
    37501 ccagcatgat ttgcgctacg atttcaccgt tattgaggtc acgttgcttc ttaatcaaac
    37561 cagaggaaca gaaggtacaa ccgatattac agccgacctg agtggtcaca cagacagata
    37621 aaccatagtg ttgacacatg agtacagtct caattaacat accgtcaggc aattcaaaga
    37681 gatatttgac tgtaccatca gcagactctt gcacaatacg ttgtttcaag ggattgacca
    37741 caaactggtc attgagctta gcaatcaaat ccttggaaag gttggtcatt tcttcaaatg
    37801 actgcacacg tttacggtag agccattccc agatttgatc tgcacggaat ttcttttctc
    37861 cctgctccaa tacccattcc tgcatggttt gatgtgccaa actatgaatt gagggtttca
    37921 tttcttctcc ttattctcta ctcacttctg acgaatgaca aaatgacgtt gttccttgtc
    37981 ctctttctga gaatgctggt ctttctgacg acgtctattt ttcttatctg cattcgactt
    38041 tcgtttagtt tgagtcggtt tctttccttt tctagaaggt gtttcttctt ccgtcttacg
    38101 cattttcttg tcaaatgatg ctcgcttagg ggcttcattt tctaagacaa aataggcaca
    38161 accataacta caatactcta aaaggtagtc ttgtaaacga ctgatttttt caagtttttc
    38221 ttctgttcgg tcatccttgt aaaaacctcg taggcgaagc tgttcgttgc tccagtcccc
    38281 cacgatataa tcaaacttgg ttaatacttc tgaaaaacgc tgattaaaag tcgtcacatc
    38341 aaaggcatcc ttgatatttt caaccaagga aaaagctatc ccttccgttt cgaccttgtc
    38401 cccgtgtaaa tggaactccg gaccaggaaa cttgttatag ttgtataatt caggtgcaat
    38461 ttcttttcgc atagatatcc tttttccacg attacttaat actttattct accataattt
    38521 ctagcagtta gcacgtttct cataaaaatg aaaaaagtct gacgattttg tcagaccaga
    38581 atcttataac ctaaaaaaga gaagaacaat tcttccctcc aactatcatt atttagcagc
    38641 tgcgtacaat tcatctactt tattccagtt gattactgaa aagaaagctt tgatgtagtc
    38701 aggacgcacg ttgcggtatt tcacgtagta agcatgttcc caaacgtcca agcccaagat
    38761 tggtttttta ccttctgaga ttggtgtgtc ttggtttgct gttgaagtca cttcaagttt
    38821 cccttctttg ttgacaacca accatgccca acctgaacca aaacgagttg ttgctgctgc
    38881 agtgaaggct gcttggaatt cttcaaatga accaaatgtt gcatcgattg ctgctgccag
    38941 ttctgctgaa ggagctgttt tctcgggagt catcaattcc cagaaaagag cgtgattcaa
    39001 gtgtccgcca ccattgttga taagtgcttg acggatatca gctgggatag attctacatc
    39061 agcaagcaag gcttcaaggt cttcaccgat ttcagggtgt ttttctaaag ctgcattggc
    39121 attgttgaca taagtttgat ggtgtttgtc atggtgcaaa tgcattgttt ccgcatcgat
    39181 gtatggttcc aaagcgtcgt atgcatatgg aagttctggt aagataatag ccatctgtaa
    39241 tacctctttt tctttctata tgaaaatgat aacgcaaaca ttcacttttt tcaagttttt
    39301 tgcttataga taaggaaatc actgacatac tttctaataa aataagcaaa tcagcaagaa
    39361 acccacgaca agataatcct gacgcgggtt gtagtttcaa caaatgtcaa ttgacctgac
    39421 tagcaatctg taagagtgcc ttttcaaaaa ggaaaccttt ttcataaaga cctgtcttaa
    39481 tctgatagtc tgtctcaatc aaataggaaa tagcttgctt caaaaagctc aaagaaagtc
    39541 ctctcgaatc tcttaatgca aacttgattt gataaggatt tgggttacgt cccagataac
    39601 tacctaaact acttgcaatc tgcgattctg tttggccaga ctccgccaaa atcttcacct
    39661 gagtaaaagt ccgaaattgt cccagcatga ctgcaatcag tttgatttca tcttcccctt
    39721 gcaaggtcaa gtctctcacc aaatcgcgcg cctgatccat ctttttagtc agaataaact
    39781 gagttaaatc aaaaatattg tcctgcaagg tcttgggaat tgcgttaaca atatcctctt
    39841 cctcaataac agaattcgcc ttataggact gtaaaaagag aagatttttc tggatttcgc
    39901 taaattgaaa ccccgacttg atgaggagat tttcaaaaga atgattggta aactgcagac
    39961 cttgtttctg actccacttt tggaaatact ggcgcaattc ttgttctttt acttctactg
    40021 catcgaagac cttggcatca cgcttaagta atttgactaa ccgtcttttg ctatccagct
    40081 ttccttctgc aaagattatc aacttggttg ttggagaagg attgtcaagg tattcctcaa
    40141 atgacttaag ctcatcatct gtcaaaaagc gtttcttagc agtcgtgata tccataaaat
    40201 aatctaatat cacgattttc tcatccgcaa agaaaggaag gctgaccaac tccagttcca
    40261 catccttgta aactacttct ttcatatcaa agtaggcaaa gttgaggtca gcagaatcat
    40321 acccaatctg tttcaacatt tgactcttca tcacttcaaa ctgaccctga tctgtccctg
    40381 taaataggct caggctcggt aaatttgata aagtcaactt ctgactttct tcaatggcta
    40441 gcatcgtctc tcctttcttc agatttttcg atttaattta gtcaatatag cgcaatttcc
    40501 cacggaaatc ttctaagctc tcgtagcctt tttccaccat gattgctttc agttcattgg
    40561 taatgcggtc aaaagcactg acgccttctt tgtgaagggt cgttcccacc tgcaccatac
    40621 ttgctccaca gaggatgtgt tcaaaggcat ctcgaccagt cagaacgcca cctgttccga
    40681 taatttggat ttgaggattt aaacgttgat aaaaggcgtg aacattggct agagcagtcg
    40741 gtttgatgta ttctccacca attccaccaa aaccattctt aggccgaata acgacagatt
    40801 cgtcttctat atagaggccg tttccgatag agttaacgca gttgacaaac ttgagcggat
    40861 atttgttgaa aatagctgcc gcttgatcaa agtgaacaat atcaaaataa ggtggcaatt
    40921 taattccaag aggtttggtg aagtaagcaa acacttctgc caaaatccgg tctgttgtct
    40981 caaaatcata ggcaatctga ggtttacctg gaacatttgg acaggaaaga tttagctcag
    41041 tcagaccacg aaaatcactc tcttggactt ttttcaaaat agtatgggtt tcctctggag
    41101 acataccgac cagagataag aagaaagttc ggttcgactc tttttcctgc aaatctaaaa
    41161 gataatccaa ataatagtct aagccattat ttggcaagcc catagagttg atggaaccaa
    41221 gtggaacatc ttggtagcgt ggctcaggat tcccctgacg gaagtccaag gtcgctgtct
    41281 tagtaacaaa ggttcctgcc gctgagtttt tgacctcttc taactcctct atcgtcatac
    41341 aagccacacc tgctgcattc atcaagcaat tgtcaaactc aaaaccagca atttgtgttt
    41401 tcgttgatac catgattcta atcctccaga tttcttttat tgctaatatt ataccataat
    41461 tttaattcta ggtttactag attctgtggt tctatctatt tattcggaaa agaaagtcta
    41521 gtacagaagt catgctatgg aaacagctag tgtattggaa gtttgaacaa ggcttgggta
    41581 acagactttt gaatgaagtc caagcaacaa ggagaaatct caaccatgag tccattccat
    41641 gactctgttg ctctagaaaa ccttgcaata gtcaagtgat aacgaataaa actttggctt
    41701 gaaatatccc catgattatc tattacgagg agaaatctca acctttatca tttttaaaga
    41761 aatattgtaa aatgaaacaa gaacagga
//
LOCUS       DAVMCN010000012        39326 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVMCN010000012 DAVMCN010000000
VERSION     DAVMCN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.012"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            181..1458
                     /locus_tag="VYP85_000796"
     CDS             181..1458
                     /locus_tag="VYP85_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1881338.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYSVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1534..3018
                     /locus_tag="VYP85_000797"
     CDS             1534..3018
                     /locus_tag="VYP85_000797"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1881339.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3079..4359
                     /locus_tag="VYP85_000798"
     CDS             3079..4359
                     /locus_tag="VYP85_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1881340.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4363..4983
                     /locus_tag="VYP85_000799"
     CDS             4363..4983
                     /locus_tag="VYP85_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1881341.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5149..6261
                     /locus_tag="VYP85_000800"
     CDS             5149..6261
                     /locus_tag="VYP85_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1881342.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6584..7009
                     /locus_tag="VYP85_000801"
     CDS             6584..7009
                     /locus_tag="VYP85_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1881343.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7020..7421
                     /locus_tag="VYP85_000802"
     CDS             7020..7421
                     /locus_tag="VYP85_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1881344.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            7496..8140
                     /gene="pcp"
                     /locus_tag="VYP85_000803"
     CDS             7496..8140
                     /gene="pcp"
                     /locus_tag="VYP85_000803"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1881345.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8168..9025)
                     /locus_tag="VYP85_000804"
     CDS             complement(8168..9025)
                     /locus_tag="VYP85_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1881346.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFILDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9155..10297
                     /gene="tgt"
                     /locus_tag="VYP85_000805"
     CDS             9155..10297
                     /gene="tgt"
                     /locus_tag="VYP85_000805"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1881347.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10398..12215
                     /locus_tag="VYP85_000806"
     CDS             10398..12215
                     /locus_tag="VYP85_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1881348.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12368..13519
                     /gene="nagA"
                     /locus_tag="VYP85_000807"
     CDS             12368..13519
                     /gene="nagA"
                     /locus_tag="VYP85_000807"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1881349.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            13682..14740
                     /locus_tag="VYP85_000808"
     CDS             13682..14740
                     /locus_tag="VYP85_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1881350.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            14891..15256
                     /locus_tag="VYP85_000809"
     CDS             14891..15256
                     /locus_tag="VYP85_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1881351.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15332..16273
                     /locus_tag="VYP85_000810"
     CDS             15332..16273
                     /locus_tag="VYP85_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1881352.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16221..17237
                     /locus_tag="VYP85_000811"
     CDS             16221..17237
                     /locus_tag="VYP85_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1881353.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17239..17565
                     /gene="comGC"
                     /locus_tag="VYP85_000812"
     CDS             17239..17565
                     /gene="comGC"
                     /locus_tag="VYP85_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1881354.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            17534..17962
                     /locus_tag="VYP85_000813"
     CDS             17534..17962
                     /locus_tag="VYP85_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1881355.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            17967..18227
                     /locus_tag="VYP85_000814"
     CDS             17967..18227
                     /locus_tag="VYP85_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881356.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18190..18651
                     /locus_tag="VYP85_000815"
     CDS             18190..18651
                     /locus_tag="VYP85_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1881357.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            18629..19042
                     /locus_tag="VYP85_000816"
     CDS             18629..19042
                     /locus_tag="VYP85_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1881358.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19179..19773
                     /locus_tag="VYP85_000817"
                     /pseudo
     CDS             19179..19773
                     /locus_tag="VYP85_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            19834..20787
                     /locus_tag="VYP85_000818"
     CDS             19834..20787
                     /locus_tag="VYP85_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1881359.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            20838..22028
                     /locus_tag="VYP85_000819"
     CDS             20838..22028
                     /locus_tag="VYP85_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1881360.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22177..22548
                     /gene="rnpA"
                     /locus_tag="VYP85_000820"
     CDS             22177..22548
                     /gene="rnpA"
                     /locus_tag="VYP85_000820"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1881361.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22523..23347
                     /locus_tag="VYP85_000821"
     CDS             22523..23347
                     /locus_tag="VYP85_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1881362.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23366..24352
                     /locus_tag="VYP85_000822"
     CDS             23366..24352
                     /locus_tag="VYP85_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1881363.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24403..25026
                     /locus_tag="VYP85_000823"
     CDS             24403..25026
                     /locus_tag="VYP85_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1881364.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25157..26614
                     /locus_tag="VYP85_000824"
                     /pseudo
     CDS             25157..26614
                     /locus_tag="VYP85_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            26637..26918
                     /locus_tag="VYP85_000825"
     CDS             26637..26918
                     /locus_tag="VYP85_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1881365.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            26995..27480
                     /locus_tag="VYP85_000826"
     CDS             26995..27480
                     /locus_tag="VYP85_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1881366.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27497..28162
                     /locus_tag="VYP85_000827"
     CDS             27497..28162
                     /locus_tag="VYP85_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1881367.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28166..29029
                     /locus_tag="VYP85_000828"
     CDS             28166..29029
                     /locus_tag="VYP85_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1881368.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29031..29735
                     /locus_tag="VYP85_000829"
     CDS             29031..29735
                     /locus_tag="VYP85_000829"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1881369.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            29914..31587
                     /locus_tag="VYP85_000830"
     CDS             29914..31587
                     /locus_tag="VYP85_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1881370.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            31699..32790
                     /gene="ulaG"
                     /locus_tag="VYP85_000831"
     CDS             31699..32790
                     /gene="ulaG"
                     /locus_tag="VYP85_000831"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1881371.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            32903..34879
                     /gene="tkt"
                     /locus_tag="VYP85_000832"
     CDS             32903..34879
                     /gene="tkt"
                     /locus_tag="VYP85_000832"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1881372.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            34996..35295
                     /gene="yajC"
                     /locus_tag="VYP85_000833"
     CDS             34996..35295
                     /gene="yajC"
                     /locus_tag="VYP85_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1881373.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35342..35770
                     /locus_tag="VYP85_000834"
     CDS             35342..35770
                     /locus_tag="VYP85_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1881374.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            35772..36182
                     /locus_tag="VYP85_000835"
     CDS             35772..36182
                     /locus_tag="VYP85_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881375.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36482..39133
                     /gene="adhE"
                     /locus_tag="VYP85_000836"
                     /gene_synonym="adhC"
     CDS             36482..39133
                     /gene="adhE"
                     /locus_tag="VYP85_000836"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1881376.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12002 a         7002 c         8825 g        11497 t
ORIGIN      
        1 taagtctgct aatttcactg ctctcaaaat ccagtgtccg caaggacgtg ccggttcgac
       61 cccggccgcc ggtatagtat agtgttagga acgttgttat tcttcgttct ttttttatat
      121 tatttttggt ataattatag ttattcaaat tttatttaga ttaagaaagt gtagggtagt
      181 atgtcttgtt ctatcgattt attaaaacat cggtatttga aaaatattaa agaaaatcct
      241 gaattgtttg tcggaattga gttggagtat tctgttgcaa gtttagaagg ggatgctaca
      301 gatgttgaag ttataaagga tctatttcat tatttagttt ctactttgga tctcaccgta
      361 gcaaaggtag atgattttgg caatctgatc cagttagtag atccgataag tcaggatgct
      421 attttatttg aagtttccta tacaacgatt gagtttgcat ttggtaaggc tgaaacgatt
      481 caagaggtcg aaaatcgttt caataattat atgaatgtaa ttcagagaaa gttagctgaa
      541 tcaaatcatg ctattgttgg ctgtggtatc catcccaact gggataaaaa tgagaattgt
      601 ccagtggctt atccacgcta tcagatgttg atggattatt tgaatttgag tagaaatatt
      661 attaaatcag atttacatca tttccctgaa tatggtactt ttatctgtgg gagccaggtt
      721 cagctggata tttcaaaaac caactactta cgggtgatta atgcttttac tcaaattgaa
      781 gcggctaagg cttatttatt tgcaaactct gaattttcgg gtgcggattg ggatacgaaa
      841 atttcaaggg atattttctg ggaagaatct atgcatggta tctatccaga gaatgttggg
      901 gtcaatgcta gactccttaa tgatgaagct gatttttttg actatctaaa tcattctgcg
      961 atttttactg cggaacgtga tgggcagacc tattattttt atcctattca ggctggggac
     1021 tatttggcta cgcctgaaat ccaagcattt gctctgaatg gggatgaggt tattatttcc
     1081 ccccaagaga aggattttga aactcatcgt agttaccagt accaagactt aacgactcga
     1141 ggaacagttg agtttcgtag tgtgtgtaca cagccacttg ataggacttt tgcttctgca
     1201 gcttttcact tgggattatt ggttaattta gacaagttag aagcttactt agaaacagca
     1261 cctttcttta aagtatttgg ttatgattac aagtctttaa ggagacaatt ttctaagaaa
     1321 aatcttacag atgaggaaga aactacgatt attgaatttt ccaaagactt actcctacta
     1381 gctgaggagg gactagtggt gagaaataag gaagaaatga cctatttaca gcctttgaga
     1441 gaagaattga gcctataatt tctcttataa agggagaatt ttctgaaaaa tcatgatata
     1501 atggacgaga ctatagataa aggatagaga gtaatgacat tagtttatca atcaacgcgt
     1561 gatgccaaca atacagtaac tgctagccaa gcaattttgc aaggtttggc gacggacggc
     1621 ggtttgttta caccggttac ttatccaaag gtagatttgg actttgacaa attgaaagat
     1681 acttcttacc aggaagttgc taagctagtt ttgtcagcat ttttagatga ctttacagct
     1741 gaggagttgg actactgtat caacaatgcc tacgatagca aatttgatac tccagctatt
     1801 gcaccattag tgaaattaga tgggcaatac aatttggaac ttttccatgg ttcaacgatt
     1861 gcctttaagg atatggcctt gtctattttg ccatacttta tgacgactgc tgctaagaaa
     1921 catggtttgg agaacaagat tgttatcttg acagcgacat ctggtgacac ggggaaagct
     1981 gctatggcgg ggtttgcgga tgtgcctggt actgagatta tcgtctttta tccaaaggat
     2041 ggtgtcagca agattcaaga gttacaaatg accactcaaa ctggcgacaa tactcatgtt
     2101 attgctattg atggtaactt tgacgatgcg caaacaaatg tgaagcacat gtttaacgac
     2161 gtggctcttc gtgaaaaatt gactaccaac aagttgcaat tttcatcagc taactctatg
     2221 aacattggtc gtctggtgcc acaaattgtt tattatgttt atgcttacgc tcaattggtt
     2281 aagactggtg aaattgtagc tggtgaaaag gttaacttca cagtaccaac aggaaacttt
     2341 ggaaatatct tggctgcctt ttatgccaaa caaattggtt tgccagttgg taaattaatc
     2401 tgtgcttcaa atgacaacaa tgttttgaca gacttcttta aaacacgtgt ctatgacaaa
     2461 aaacgtgagt ttaaggtaac aaccagccca tctatggata tcttggtatc ttcaaacttg
     2521 gagcgcttga ttttccatct tttgggaaat aatgctgaaa agacaactga acttatgaat
     2581 gccttgaaca cgcaaggaca atataagttg acagactttg atgcagagat tttggacctc
     2641 tttgcagctg aatatgcgac tgaggaagaa acggcagcag agatcaagcg tgtttgtgag
     2701 ttagattctt atatcgagga ccctcataca gctgttgctt cagcagttta taaaaaatac
     2761 caatcggcca ctggagatgt aactaagaca gtgattgctt caacagctag tccatacaag
     2821 ttcccagtag ttgcagtaga agctgtaact ggaaaagcag gtttaacaga ctttgaagcc
     2881 ttggctcaat tacatgaaat ctcaggcgtt gcagtgccac cagcagttga tgggcttgaa
     2941 atagctccaa ttcgtcacaa gacaacagtg gcagctgctg acatgcaagc agcggttgag
     3001 gcttatttag gactttaaga cagagggagc aaactcggtt gggaaaccaa ctgagtttct
     3061 tttcatcagg aggagagatt gtttaagaaa aataaagaca ttcttaatat tgcattgcca
     3121 gctatgggtg aaaacttttt gcagatgcta atgggaatgg tggacagtta tttggttgct
     3181 catttaggat tgatagctat ttcaggggtt tcagtagctg gtaatattat caccatttat
     3241 caggcgattt tcatcgctct gggagctgct atttccagtg ttatttcaaa aagcataggg
     3301 cagaaagacc agtcgaagtt ggcctatcat gtgactgagg cgttgaagat taccttacta
     3361 ttaagtttcc ttttaggatt tttgtccatc ttcgctggga aagagatgat aggacttttg
     3421 gggacggaga gggatgtagc tgagagtggt ggactgtatc tatctttggt aggcggatcg
     3481 attgttctct taggtttaat gactagtcta ggagccttga ttcgtgcaac gcataatcca
     3541 cgtctgcctc tctatgttag ttttttatcc aatgccttga atattctttt ttcaagtcta
     3601 gctatttttg ttctggatat ggggatagct ggtgttgctt gggggacaat tgtgtctcgt
     3661 ttggttggtc ttgtgatttt gtggtcacaa ttaaaactgc cttatgggaa gccaactttt
     3721 ggtttagata aggaactgtt gaccttggct ttaccagcag ctggagagcg acttatgatg
     3781 agggctggag atgtagtgat cattgccttg gtcgtttctt ttgggacgga ggcagttgct
     3841 gggaatgcaa tcggagaagt cttgacccag tttaactata tgcctgcctt tggcgtcgct
     3901 acggcaacgg tcatgctgtt ggcccgagca gttggagagg atgattggaa aagagttgct
     3961 agtttgagta aacaaacctt ttggctttct ctgttcctca tgttgcccct gtcctttagt
     4021 atatatgtct tgggtgtacc attaactcat ctctatacga ctgattctct agcggtggag
     4081 gctagtgttc tagtgacact gttttcacta cttgggaccc ctatgacgac aggaacagtc
     4141 atctatacgg cagtctggca gggattagga aatgcacgcc tcccttttta tgcgacaagt
     4201 ataggaatgt ggtgtatccg cattgggaca ggatatctga tggggattgt gcttggttgg
     4261 ggcttgcctg gtatttgggc agggtctctc ttggataatg gttttcgctg gttatttcta
     4321 cgctatcgtt accagcgcta tatgagcttg aaaggatagg aaatgcaaaa aacagctttt
     4381 atttgggatt tagacgggac tttattggac tcttacgaag cgattttatc agggattgag
     4441 gagacttttg ctcagttttc tattccttat gataaggaga aggtgagaga gtttatcttc
     4501 aagtattcgg tgcaagattt gcttgtgcgg gtggcagaag atagaaatct ggatgttgag
     4561 gtgctaaatc aggtgcgtgc ccagagtctg gctgagaaga atgctcaggt agttttgatg
     4621 ccaggtgcgc gtgaggtgct agcttgggca gacgaatcag gaattcagca gtttatatat
     4681 actcataagg ggaacaacgc ttttaccatt ctcaaggact tgggggtgga atcctatttt
     4741 acagagattt taaccagtca gagtggcttt gtgcggaagc caagtccaga agcggctacc
     4801 tatctgctag ataagtatca gttgaattct gataatactt attatatagg ggatcggact
     4861 ctggatgtgg aatttgccca gaatagtggg attcaaagca tcaacttttt agagtctact
     4921 tatgaaggga atcacaggat tcaagcgtta gcagatattt cccgtatttt tgagactaag
     4981 tgataaaaag attgtgtcag ttttgtgaca gagacctaac aaactatttc aagtaaccta
     5041 gtttgttaca aggaatagac agttctgtta aataggcccg agagggcttt ttttctacat
     5101 tttttgtgtt atgatagaca ggtactcatt tgaaaggaat ttgaaagaat gaagaaaaga
     5161 atgttattag cgtcaacagt agccttgtca tttgccccag tattggcaac tcaagcagaa
     5221 gaagttcttt ggactgcacg tagtgttgag caaatccaaa acgatttgac taaaacggac
     5281 aacaaaacaa gttataccgt acagtatggt gatactttga gcaccattgc agaagccttg
     5341 ggtgtagatg tcacagtgct tgcgaatctg aacaaaatca ctaatatgga cttgattttc
     5401 ccagaaactg ttttgacaac gactgtcaat gaagcagaag aagtaacaga agttgaaatc
     5461 caaacacctc aagcagactc tagtgaagaa gtgacaactg cgacagcaga tttgaccact
     5521 aatcaagtga ccgttgatga tcaaactgtt caggttgcag acctttctca accaattgca
     5581 gaagttacaa agacagtgat tgcttctgaa gaagtggcac catctacggg cacttctgtc
     5641 ccagaggagc aaacgaccga aacaactcgc ccagttgaag aagcaactcc tcaggaaacg
     5701 actccagctg agaagcagga aacacaagca agccctcaag ctgcatcagc agtggaagta
     5761 actacaacaa gttcagaagc aaaagaagta gcatcatcaa atggagctac agcagcagtt
     5821 tctacttatc aaccagaaga gacgaaagta atttcaacaa cttacgaggc tccagctgcg
     5881 cccgattatg ctggacttgc agtagcaaaa tctgaaaatg caggtcttca accacaaaca
     5941 gctgccttta aagaagaaat tgctaacttg tttggcatta catcctttag tggttatcgt
     6001 ccaggagaca gtggagatca cggaaaaggt ttggctatcg actttatggt accagaacgt
     6061 tcagaattag gggataagat tgcggaatat gctattcaaa atatggccag ccgtggcatt
     6121 agttacatca tctggaaaca acgtttctat gctccattcg atagcaaata tgggccagct
     6181 aacacttgga acccaatgcc agaccgtggt agtgtgacag aaaatcacta tgatcacgtt
     6241 cacgtttcaa tgaatggata aacccgactt gataacatca ttttgacgaa tgagatctag
     6301 ctttcgtgat ggaaagcgat tctcgttcgt tttttctttg tcatactctt cgaaaatctc
     6361 ttcaaaccac gtcagtttta tctgaaacct caaagctgtg ctttgagcaa cctgcgacta
     6421 gcttcctagt ttgctttttg attttcattg agtatcaatt tgaatggaaa atggaaagtt
     6481 atcatcttgt aatgagttaa gcaacattct tgcaatctat tttactttat atcacaatta
     6541 attagtcaac tattgataaa tcaataaaaa gagaggggaa gaaatgctag agattcaaga
     6601 tttactgtat caactccgct tgtctgagca agcgagtacg caattgtttg aaaaaaggct
     6661 tgggattagt ttgacacggt atcagatttt actgtttttg ctggagcatt ctccttgtaa
     6721 ccaaatggcg attcaggagc gtttgaaaat tgatcaggct gctttgacac ggcatttcaa
     6781 gattttggaa acggaaggtt tggtggagcg tcatcgtaat cctgaaaatc agcgggaagt
     6841 gttggtagag gctgcgaagt atgccaagga gcagttagtg gtgaatcccc ctctgcaaca
     6901 tatcaaggtt aaggaagaga tggaaagtat cttaacagag tttgagagaa cagaactcag
     6961 ccgtttatta aataaattgg ttttgggtat tgaaaatata gaaatttaag gagaaataga
     7021 tgtcaattat tacaattatt ttaacaacga tcgttgcttt ggagcatttt tacatttttt
     7081 atttggaaag tattgctacg cgatcagatg cgactagtcg tgtatttaat atggaaaagg
     7141 aagaattggc tcatccgtca gtaagttcat tgttcaaaaa tcaagggatt tataaggctc
     7201 tgctaggagt ctttctctgg tatggcattt atttctcaca gaatttagaa attgtgacta
     7261 tttttgtctt atttgtgatt ggtgctgcga cttacggctc tttaacagcg gataaaaaaa
     7321 ttattttgaa gcaaggtgga tcagctattt tggccttgat tagtatttta ctctttaaaa
     7381 tacacttgaa ggtcgattct aatctcgcta atccttttta atccagaata agggaaatat
     7441 gttatacttg tttttaagaa aaaagtctca ttgaattggt tttgaggagt tagaaatgaa
     7501 agtattagtg acaggttttg agccctttgg aggggaaaag ggcaatccaa ctttggaggc
     7561 cattaaaggt ttaccagctg aaatccatgg tgctgaggtc cgttggctag aggtgccgac
     7621 agtttttcac aaatctgctc aagtattgga agaagagatg aatcgttatc aacctgactt
     7681 tgtcctttgt attgggcaag ctggtggaag aactagtgtg acacctgaac gagtggccat
     7741 taatcaagac gatgcacgca tttctgataa cgaagataat caaccgattg accgtcccat
     7801 tcgcccagat ggtgcttcgg cctactttag tagtttgccg attaaagcga tggttcaagc
     7861 tataaaaaaa gagggcttac cggcctctgt ttccaatacg gcagggactt ttgtctgcag
     7921 ccatttgatg tatcaggctc tctatttggt agaaaagaaa tttccatatg ttaaggcagg
     7981 ttttatgcat attccttata tgatggaaca ggtggtgaac agaccgacta ctccaactat
     8041 gagtttagtg gatattcggc gagggataga agcagcaatc ggcgctatga tagaacatgg
     8101 ggatcaggaa ctcaagttgg taggcggaga aactcattga tagaaaaaag cttgagggga
     8161 aaaaccttca agcttttgga cgttttcgag ccaatactgc tcggtaaaac ataattttag
     8221 tgcattggat ataaggtagg agtgaaaaac tagcaatgcc aaaggtaatc caattgagga
     8281 agtaccaagg aagaagctgt aaatctagga taaagtgctg gaacttgtag cccttcataa
     8341 aggaacggct agtttttagg attcgtcttg gtgggacctg tcctaggtct agactataac
     8401 agagaagaaa ttccacctgt gaataggcat aatactgtgg aatatagagg atatttccta
     8461 caatgatcaa gatgagactt gcaagaaagt agagtccaaa gaccatgagg aaacgctcgg
     8521 tttcaactga tgagagatct agatttggaa actcaggatg tagggtgacg aattttttgg
     8581 ctaaaaagct actataaaag aggagataaa tcccaagtaa attagggata ctccataaaa
     8641 agagatagaa acgtttgaga agtagggtca aaaaggtttg agaaaagcgc tcctcatcaa
     8701 agagagctag gctgtttttt acagatggct ccgttttaga atctttcatg agtgtcagtg
     8761 ttgcatagac ggaactggtc aaaagaatag tcccgataaa ggagactagt agaggaaaga
     8821 ggtaggcttg aagtatttgg ccaagtatgc tgaaaaatgg ctgttctaaa acagtcccgt
     8881 ggatccgaga taagggatta agaaaactag ataagatgac cagcatactg ggaaggatat
     8941 agaggagaaa gagacggggg gtgtcagcct gaaaatgttt tgactcctga cgaattgttt
     9001 ttaaatcaat ttttggatag ttcattctct tattatacca tagttcttat acatagttcg
     9061 tgacagttcc tacttttttt gataaaatca tacagtgtgt ccttgggcac actgtatgaa
     9121 ctgggactgt ctttcccagc ttcggaggta aaaaatgtca gattcaccaa tcaaatatcg
     9181 tttgattaag aaagaaaaac acacaggagc tcgtctagga gaaatcatca ctccccacgg
     9241 tacctttccg acacctatgt ttatgccagt tgggacacaa gccactgtca aaactcagtc
     9301 acctgaagaa ttgaaggaga tgggttcggg aattatccta tcaaacactt atcatctctg
     9361 gcttcgccct ggagatgaac tcattgcacg cgctggtggt ctccacaagt tcatgaattg
     9421 ggaccagcct atcttgacag atagtggtgg ttttcaggtt tattctttag cagatagccg
     9481 taatatcaca gaagaaggag taacctttaa aaatcatcta aatggttcta agatgttcct
     9541 atccccagaa aaagccatct ctattcagaa taatctgggt tcagacatca tgatgtcctt
     9601 tgatgaatgt cctcagtttt atcaacctta tgactacgtt aagaaatcga tagagcgtac
     9661 cagccgttgg gctgagcgtg gtttgaaggc tcaccgtcgt ccacatgacc aaggtttgtt
     9721 tggaattgtg caaggtgcag gatttgaaga ccttcgccgc caatcagctc atgatcttgt
     9781 cagcatggat ttctcaggct actctatcgg tggtttggca gtgggagaaa cccatgaaga
     9841 gatgaatgcg gtcttggact ttacaactca actgctgcct gaaaataaac ctcgttatct
     9901 gatgggtgtg ggagcgccag atagcttgat cgatggggtc attcgtgggg tggatatgtt
     9961 tgactgtgtc ttaccgactc gaattgctcg taacgggact tgtatgacca gtcaaggacg
    10021 tttggttgtg aaaaatgccc agtttgctga ggactttacg ccactggatc ctgagtgtga
    10081 ttgctacaca tgtaataact atacacgcgc ttaccttcgt cacctgctca aggctgatga
    10141 aacctttggg atccgcttga ctagctacca caatctttac ttcttgctta acctgatgaa
    10201 gcaagtgcga caagccatca tggatgacaa tctcttggaa ttccgtgagt attttgtgga
    10261 aaaatatggc tataataagt caggacgtaa tttctaaaat ggaattgata taagctaaaa
    10321 atcctaagtt ttctcttagg atttttcttc tttttttgat agaataaagt gtacaatgaa
    10381 aggaagaata aactcgtatg cgcattaaat ggttttcctt ggttaggatt acaggtttac
    10441 ttttggtact cttgtatcac ttctttcaga cgatctttcc tggaggattt ttcggggtag
    10501 atgtcttttt cacattttca ggtttcctga ttacagctct actcattgaa gaattttcta
    10561 aaaaccatga gattgatttg ataggatttt ttagaagacg cttttatcgg attgtgccac
    10621 ctgtggtttt gatggtcttg gtgaccatgc cttttacttt cttggttcgc caagactatg
    10681 ttgctggaat tggtggccag attgcgagcg tcttaggctt tatgaccaac ttctatgaac
    10741 tcctaacagg tgggagttat gaatctcagt tcattcctca tttgtttgtt cataattgga
    10801 gtttggcagt tgaggttcac tactatattc tttggggatt ggcagtttgg ttcttatcca
    10861 aacaagctaa atcaaatggt cagttgaagg ggatggtctt tctcttatct gctgttgcct
    10921 tcttgatcag tttcttctcc atgtttattg gtagttttct agtgacctct tattcctctg
    10981 tttatttctc cagtttaact catgtctatc cattcttttt gggaagtatg ttagcaacta
    11041 ttgtaggcgt tcgtcagacg acttccctcg tcaagcagtt ggataaaatc tgggatttac
    11101 gaaagacttt ggtagttttt ggaggaggct ttggtttcct agttcttttg actttctttg
    11161 tcaaattcac ttatcttttt gcctatctta tcggcttctt acttgccagt cttgcagctc
    11221 ttgccatgat tctggcggcg cgtgtcttac atgaaaagac acatcatata caggagccga
    11281 agattatcag ctttttagcg gatactagct atgcggttta tcttttccat tggcctttct
    11341 atatcatttt ctcacagttg acatcaaatc ttcttgctgt attactgact ctgatttgtt
    11401 cttatggctt tgccagtctg tcattttatg tattggaacc ttggattgca ggcaagaaca
    11461 cacctattgt ccaaaccctt cgtcccctgc cttatattca cgcaattctt gcagcaggta
    11521 caggaatctt gaccatcatt gtctgcacgg tgaccttgtt ggcaccacaa gtgggagcgt
    11581 ttgagacaga cttgactgtc aatggcttga agcaagctgc aacaaatatt ggccagacca
    11641 aggtgatggc agaacgggca gatgcaaaca gtttgggaat tgctgatggc actatgttaa
    11701 ttggtgactc agtggcttta agggcaaata cagcactaca gacagctctt cctggagcac
    11761 agattaacgc gcaggtcagc gtaacaacca agaccgcaaa tgaaatcatg ctaaataata
    11821 gccagaataa atttttacct aagacggtgg tcattgcgac tggggtaaat aatcctgaga
    11881 attacaagga tgactgggac agtatcgtga aaaatcttcc taagggacac catatgattt
    11941 tggtgactcc ttatgaggga gataagacaa aagagaccta tgccatcgtt gagaaggctg
    12001 ctgcctatat gagagaattg gcagagaaga caccttacat tacgatagca gattggaatc
    12061 aagttgcgaa agagcatcca gaaatttggg caggaacaga ccaggttcat ttcgggagtg
    12121 agagtagcac tatcgaagca ggagcaaaat tgtatgcaga tacgattgcc acagctttgc
    12181 agacagctca agacaagccg gttaaatcaa aataacttgt attaaaaaag agaagagttg
    12241 gagaaatcca gctcttttaa aatatctcca aaaaataggt ctataccatt tacaaataaa
    12301 aaagaaaggt ttataatgta attgacataa taaattgtag aatcaatctt ttaaggaggt
    12361 taacattatg cctaactata ttaaagcgga tcagtttttc tacccacacg gagttcgtcg
    12421 aggtggttac ttggaacttg tggacggcaa gtttgggaaa catgtagagc agattcctga
    12481 aggggctgag gtgattgact atacaggtta tagcattgcc ccaggtcttg tggatactca
    12541 tattcatgga tatgcaggtg tagatgtgat ggacaacaac attgaaggta cattgcatac
    12601 tatgagtgaa ggacttctta gtaccggtgt taccagtttc ttacccacaa ctttaacagc
    12661 cacttatgag caattgcttg cagtcactga aaatcttgga aaccattata aagaagcaac
    12721 aggtgctaag attcgtggga tttattatga aggtccatat ttcacagaaa cttttaaggg
    12781 ggcacaaaat ccaacttata tgagagaccc gggtgttgag gagtttcatt cttggcaaaa
    12841 agcggcaaat ggcttgctta ataaaattgc ccttgcacca gaacgtgatg gggtggaaga
    12901 ctttgttcgt acagttacgg gcgaaggtgt gacggttgct cttggacatt caaacgcgac
    12961 ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt gtttgggtgc atgcctacaa
    13021 tggaatgcgt gggttgactc accgtgaatt gggtatggtt ggagccatgt accaattgcc
    13081 acatacctat gcagagttga tctgtgatgg tcaccacgta gatccaaagg cttgcgaaat
    13141 tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc acagactgta tgacagctgg
    13201 gggattggaa gacggagatt atatgttggg agaattccca gttgtcgttg caaatggaac
    13261 tgcacgcctc aaatcgacag gtaacttggc aggttctatc ctcaaactca aagatggttt
    13321 gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa gcagtcatga tggccagctt
    13381 caacccagct aaatccgttc acatcgatga cgtctgtggc caaatccgtg aaggctacga
    13441 cgctgacttc atcgtattag ataaagattt ggaattggta gcaacctacc tagatggcgt
    13501 aaaacgttat caagcataag agagaaagca gaagttagag actaacttct gcttttttat
    13561 gcagggtact ttactggtaa ataaaaagtt aaaaaaatca caaaaaaagc ttgaagaaac
    13621 aaagaaaaag gcttacaatt gaactataaa tattacaaat aaaaaaacgg aggagtgctt
    13681 tatgaaagcc tatacttatg ttaaaccagg acttgcttct tttgttgatg tagacaaacc
    13741 agttattcgc aagccaacag acgctattgt gcgtattgta aaaaccacta tttgtggaac
    13801 agacctccat attatcaaag gggatgttcc tacttgccaa agtggtacca ttcttggcca
    13861 cgaagggatt gggattgttg aagaagttgg ggaaggagtt tccaacttca aaaaaggtga
    13921 caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc tactactgta aaaaaggaat
    13981 ttatgctcac tgtgaagacg aagggggctg gattttcggt cacttgattg atggtatgca
    14041 ggctgaatat ctacgtgtcc ctcatgcaga taatactctt taccatactc cagaagactt
    14101 gtcagatgaa gctttggtta tgctgtcaga cattctgcct actggatatg aaattggtgt
    14161 cttaaaaggg aaagtagaac ctggttgcag cgtagccatt attggttcag gtccagttgg
    14221 attggctgct cttttaacag cccaattcta ttcaccagct aaattgatta tggtagacct
    14281 agacgataac cgcttggaaa ctgccctatc attcggtgcg actcataagg ttaattcttc
    14341 agaccctgaa aaagccatta aagaaattta tgatttgaca gatggtcgtg gtgtggatgt
    14401 cgctatcgaa gctgttggta ttcctgcaac atttgatttc tgtcaaaaga ttatcggtgt
    14461 agacggaacg gttgccaact gtggtgtgca tggtaaacca gttgaattcg atttagataa
    14521 actttggatt cgcaacatca atgtaacaac tggtttggta tctacaaata cgactccaca
    14581 attgttgaaa gcgcttgaaa gtcataagat tgaaccagaa aaattggtaa ctcactattt
    14641 caaactcagt gaaattgaaa aagcctacga agtcttcagt aaggcagcag accaccatgc
    14701 cattaaggtc attatcgaaa acgatatctc agaagcctaa gtagtaaaaa tatttttgta
    14761 cataagtaaa tagaaattca gtcatccatc agatggctgg attttttatc aaaaaattaa
    14821 gaaatgagca tatttctttc cttgtctggc ggaattggtt ataatatacg gtacaaagga
    14881 atgaatgaat atgtatcgtg ttatagaaat gtacggagat tttgaaccgt ggtggttctt
    14941 agaaggttgg gaagaagata ttgtagcaag tagaaaattt gaccagtatt atgatgctct
    15001 caaatactac aaaacttgct ggtttagatt ggaacaagaa tcccctcttt ataaaagtag
    15061 aagcgacttg atgaccattt tttgggaccc ggaagaccaa cgctggtgtg atgaatgtga
    15121 tgagtattta caacaatacc attctttggc tcttttgcag gatgagcagg ttatcccaga
    15181 cgaaaaacta cgctcaggct atgaaaaaca aaccagtcag gaaaggaatc gttcttgccg
    15241 tatgaaatta aaatagagaa aagtaacttt tttggagttg ctttttttat ttttctaacg
    15301 ctttgcgaat agtataggtg aggaggtaag tatggttcaa gaaattgcac aagaaatcat
    15361 tcgctcggct cggaaaaaag gggcgcaaga catttatttt gtccccaagt tagacgccta
    15421 tgagcttcat atgagggtag gagacgagcg ctgtaaaatt ggtagctatg attttgaaaa
    15481 gtttgcagcc gttatcagtc actttaagtt tgtggcgggt atgaatgtgg gagaaaaaag
    15541 acgtagtcaa ctgggttcct gtgattatgc ctatgaccag aagatagcgt ctctacgttt
    15601 atctactgta ggcgattatc gggggcatga gagtttggtt atccgtttgt tgcacgatga
    15661 ggagcaggac ttgcattttt ggtttcagga tattgaagaa ttaggcaagc agtacaggca
    15721 acggggactc tatctttttg ctggtccggt tgggagtggt aagacgacct tgatgcatga
    15781 attgtccaag tcactcttta aaggacagca agttatgtcc atcgaagatc ctgtcgaaat
    15841 caagcaggac gacatgcttc agttgcagtt gaacgaagca atcggcctaa cctatgaaaa
    15901 tctaatcaaa ctttccttgc gtcatcgacc agatctcttg attatcggag aaattcgtga
    15961 cagcgagacg gcgcgtgcag tggtcagagc tagtttgaca ggtgcgacag tcttttcaac
    16021 cattcacgcc aagagtatcc gaggtgttta tgagcgtctg ctggagttgg gtgtgagtga
    16081 agaagaattg gcagttgttc tgcaaggagt ctgctaccag agattaatcg ggggaggagg
    16141 aatcgttgac tttgcaaaca gagattatca agaacaccaa gcagccaagt ggaatgagca
    16201 aattgaccag cttcttaaag atggacatat cacaagtctt caggctgaga cggaaaaaat
    16261 tagctacagc taagcaaaaa aatatcatca ccctatttaa caatctcttt tctagcggtt
    16321 ttcatctggt ggagaccatc tcctttttag ataggagttc cttgttggac aagcagtgtg
    16381 tgacccagat gcgtacaggt ttgtctcagg ggaaatcatt ctcagaaatg atggaaagtt
    16441 tgggatgttc aagtaccatt gtcactcagt tatctctagc tgaagttcat ggcaatcttc
    16501 acctgagttt gggaaagata gaagaatatc tagacaatct ggccaaggtc aagaaaaagt
    16561 taattgaagt agcgacctat cctttgattt tgctgggttt tcttctctta attatgctgg
    16621 ggctacggaa ttacctgctc ccacaactgg atagtagcaa tattgccacc cgaattatcg
    16681 gtaatctgcc acaaattttt ctaggcatgg tagggcttgt ttccgtgctt gcccttttag
    16741 cactaacttt ttataaaaga agttctaaga tgagtgtctt ttctatctta gcacgccttc
    16801 cctttattgg aatctttgtg cagacctact tgacagccta ttatgcacgt gaatggggga
    16861 atatgatttc acagggaatg gagctgacgc agatttttca aatgatgcag gaacaaggtt
    16921 cccagctctt taaagaaatc ggtcaagatc tggctcaaac cctgaaaaat ggccgtgaat
    16981 tttctcagac gataggaacc tatcctttct ttaggaagga attgagtctc atcatagagt
    17041 atggggaagt taagtccaag ctgggtagtg agttggaaat ctatgctgaa aaaacttggg
    17101 aagccttttt tacccgagtc aaccgcacca tgaatttggt gcagccactg gtttttatct
    17161 ttgtggcact gattatcgtt ttactttatg cggcaatgct catgcccatg tatcaaaata
    17221 tggaggtaaa tttttaaaat gaaaaaaatg atgacattct tgaaaaaagc taaggttaaa
    17281 gcttttacat tggtggagat gttggtggtc ttgctgatta tcagcgtgct tttcttgctc
    17341 tttgtaccta atctgaccaa gcaaaaagaa gcagtcaatg acaaaggaaa agcagctgtt
    17401 gttaaggtgg tggaaagcca ggcagaactt tatagcttgg aaaagaatga agatgctagc
    17461 ctaagcaagt taaaagacga tgggcgaatc acggaagaac aggttaaagc ttataaagaa
    17521 tacaatgata aaaatggagg agcaaatcgt aaagtcaatg attaaggcct ttaccatgct
    17581 ggaaagtctc ttggttttgg gtcttgtgag tatccttgcc ttgggcttgt ccggctctgt
    17641 tcagtccact tttgcggcag tagaggaaca gattttcttt atggaatttg aagaactcta
    17701 tcgggaaacc caaaaacgca gtgtagccag tcagcaaaag actagtctga acttagatgg
    17761 gcagacgatt agcaatggca gtcaaaagtt gccagtccct aaaggaattc aggtcccatc
    17821 aggccaaagt attacatttg accgtgctgg gggcaattcg tccctggcta aggttgaatt
    17881 tcagaccagt aaaggagcga ttcgctatca attatatcta ggaaatggaa aaattaaacg
    17941 cattaaggaa acaaaaaatt agggcagtga ttttactgga agcagtagtc gctctagcta
    18001 tctttgccag cattgcgacc ctccttttgg gacaaattca aaaaaatagg caagaggaag
    18061 caaaaatctt gcaaaaggaa gaagtcttga gggtagctaa gatggccctg cagacggggc
    18121 aaaatcaggt aagcatcaac ggagttgaga ttcaggtatt ttctagtgaa aaaggattgg
    18181 aggtctacca tggttcagaa cagttgttgg caatcaaaga gccataaggt caaggctttt
    18241 accttgttag aatccctact tgccctcatt gtcatcagtg ggggattact cctttttcaa
    18301 actatgagtc agctcctcat ttcagaagtt cgctaccagc aacaaagcga gcaaaaggag
    18361 tggctcttgt ttgtggacca acttgaggca gaattagacc gttcgcagtt cgaaaaagta
    18421 gaaggcaatc gcctatacat gaagcaagat ggcaaggaca tcgccatcgg taagtcaaag
    18481 tcagacgatt ttcgtaaaac gaatgctcgt ggtcgaggtt atcagcctat ggtttatggc
    18541 ctcaaatcag ctcagattac agaggacaat caactggttc attttcgttt ccagtttcaa
    18601 aaaggcttag aaagggagtt catctatcgt gtggaaaaag aaaaaagtta aggcaggtgt
    18661 tctcctctac gcagtcacca tagcagccat ctttagtctt ttgttgcaat tttatttgaa
    18721 ccgacaagtc gcccactatc aagactatgc tttgaataaa gaaaaattgg ttgcttttgc
    18781 tatggctaaa cgaaccaaag ataaggttga gcaagaaagt ggggaacagg tttttaatct
    18841 aggtcaggta agctatcaaa acaagaaaac tggcttagtg acgagggttc gtacggataa
    18901 gagccaatat gagtttctgt ttccttcagt caaaatcaaa gaagagaaaa gagataaaaa
    18961 ggaagaggta gcgaccgatt caagcgaaaa agtggagaag aaaaaatcag aagagaagcc
    19021 tgaaaagaaa gagaattcct agtcaattca actataatgc gttgaatcca gaatagtcca
    19081 ctgtagtttc tagaaaattg ctggaaatgg atgttaagct ccaattcatt tgtttatatc
    19141 ttatttcagt ttactatact ttgtgctaaa ttaaagatat gaaacatgat tttaaccaca
    19201 aagcagaaac tttcgatttc cctaaaaata tcttcctcgc aaacttggta tgtcaagcag
    19261 ccgagaaaca gattgatctt ctatcataca aagaaatttt agatttcggt ggtggcacgg
    19321 gtctattagc cttgccccta acccctagcc aagcaggcta agtcagtcac tcttgtagac
    19381 atttctgaga aaatgttgga gcaagctcgt ttgaaagtgg agcagcaagc aatcaagaat
    19441 atccagtttt tggagcaaga tttaccgaaa aatcccttgg agaaagagtt tgattgcctt
    19501 gctgttagtc gggttcttca tcatatgcct gatttggatg cggctctctc actgtttcat
    19561 caacatttga aggaagatgg gaaactcatc attgctgatt ttaccaagac agaagctaat
    19621 catcatggat ttgatttagc tgaactggaa aacaagctaa ttgagcatgg tttttcatct
    19681 gtgcatagtc agattctcta tagcgctgaa gacctgtttc aaggaaatca ctcagaattc
    19741 tttttaatag tagcccaaaa atcactcgcc tagtcaggga gtgatttttc tataagaatg
    19801 gaaaaaagaa gggaaatttg ataagatagg aatatggatt ttgaaaaaat tgaacaagct
    19861 tatacctatt tactagagaa tgtccaagtc atccaaagtg atttggcgac caacttttat
    19921 gacgccttgg tggagcaaaa cagcatctat ctggatggtg agactgagct agaacaggtc
    19981 aaagacaaca atcagaccct taagcgttta gcactacgca aagaagaatg gctcaagacc
    20041 taccagtttc tcttgatgaa ggctgggcaa acagaaccct tgcaggccaa tcaccagttt
    20101 acaccggatg ctattgcttt acttttggtg tttattgtgg aagagctgtt taaagaggag
    20161 gaaattacta tcctcgaaat gggttctggg atgggaattt tgggcgctac tttcttgacc
    20221 tcgcttacta aaaaggtgga ttatttggga atggaagtgg atgatttgct gattgatttg
    20281 gcagctagca tggcagatgt aattggtttg caggctggct ttgtccaagg agatgcagtt
    20341 cgtccacaaa tgctcaaaga aagtgatgtg gtcatcagcg acttgcctgt tggctattat
    20401 cctgatgatg ccgttgcgtc gcgccatcaa gttgcttcta gtcaagaaca tacttacacc
    20461 catcacttgc tcatggaaca aggacttaag tacctcaagt cagacggata cgctattttt
    20521 ctagctccga gtgatttgtt gaccagtcct caaagtaatt tgttgaaagt ctggttgaaa
    20581 gaggaggcaa gtctggttgc tatgattagt ttacctgaaa atctctttgc taatgctaaa
    20641 caatctaaga ctatttttat cctacagaag aaaagtgaaa tagcagtaga gccttttgtt
    20701 tatccacttg ctagcttgca agatgcaagt gttttaatga aatttaaaga aaattttcaa
    20761 aaatggactc aaggtactga aatataaaat agattttgtt ataatagttg aaaacgctta
    20821 aaaaggggta tcatgttatg acaaaaacaa ttgcaatcaa tgcaggaagt tcaagtttga
    20881 aatggcaatt atacttaatg ccagaagaaa aagtattggc gaaaggtttg attgaacgta
    20941 tcggtttgaa agattcaatt tcaactgtaa aatttgacgg ccgttctgaa caacaaattt
    21001 tggatattga aaatcataca caagctgtta aaattttatt ggatgacttg attcgtttcg
    21061 atattatcaa ggcttatgac gagattacag gtgttggaca tcgtgttgtt gctggtggag
    21121 aatatttcaa agaatcaaca gttgttgagg gagatgtttt agaaaaagtt gaagagttga
    21181 gtttgttggc tcctctacac aacccggcaa atgcagcagg tgttcgtgcc ttcaaggaat
    21241 tgttgccaga cattaccagt gtagttgttt ttgatacttc cttccacaca agtatgccag
    21301 agaaagctta tcgctaccct ctaccaacaa aatattacac agaaaacaag gttcgtaaat
    21361 acggtgctca tggtacaagt caccagtttg tagcaggaga agctgcaaaa ctcttgggac
    21421 gtccattaga agacttgaag ttaattacct gtcatattgg taacggaggc tcaattacag
    21481 ctgtgaaagc cggcaaatct gtagacactt ctatggggtt cactcctctt ggtggtatta
    21541 tgatgggaac gcgtacaggg gatattgatc cagctatcat tccttattta atgcaatata
    21601 cagaggattt taacacacca gaagatatca gtcgtgttct taaccgtgaa tcaggtcttt
    21661 tgggagtttc tgctaattct agcgatatgc gcgatataga agcagctgta gcagaaggga
    21721 atcacgaggc tagcttggct tatgaaatgt atgttgaccg tatccaaaaa catatcggtc
    21781 agtaccttgc agtgctaaat ggagcagatg ccattgtttt cacagcaggt gtcggtgaaa
    21841 atgcagagag tttccgtcgt gatgtaatct cagggatttc gtggtttggt tgtgatgttg
    21901 atgatgaaaa gaatgtcttt ggcgttacag gagacatctc aacagaggca gctaaaatcc
    21961 gtgtcttggt tattccaaca gatgaagaat tagtcattgc ccgtgacgtt gaacgcttga
    22021 aaaaataagt gaaactaaaa aaatattcaa tacaaggagt tgggaaagtt atttttccag
    22081 cttctttttc tgatgaaatt gtccaaaacc ttgctatgat tggctttttt gaaaaatatg
    22141 gtataatagt agtaatttaa tagatggagt tgagttttga agaaaaactt tcgtgtaaaa
    22201 agagagaaag attttaaggc gattttcaag gaggggacaa gttttgctaa tcgcaaattt
    22261 gtggtctacc aattagaaaa ccagaaaaac cattttcgag taggtctatc agttagcaaa
    22321 aaactgggga atgccgtcac tagaaatcaa attaagcgac ggattcggca tattatccag
    22381 aatgcaaaag ggagtctggt agaagatgtc gactttgttg tcattgctcg aaaaggagtc
    22441 gaaaccttgg gatacgcaga gatggagaaa aatctactcc atgtattaaa attatcaaag
    22501 atttaccggg aaggaaatgg gagtgaaaaa gaaactaaag ttgactagtt tgctaggact
    22561 gtctctgtta atcatgacag cctgtgcgac taatggggta actagcgata ttacagccga
    22621 atcggctgat ttttggagta aattggttta cttctttgcg gaaattattc gctttttatc
    22681 gtttgatatt agtatcggag tggggattat tctctttacg gtcttgattc gtacagtcct
    22741 cttgccagtc tttcaggtgc aaatggtggc ttctaggaaa atgcaggaag ctcagccacg
    22801 cattaaggcg cttcgagaac aatatccagg tcgagatatg gaaagcagaa ccaaactaga
    22861 gcaggaaatg cgtaaagtat ttaaagaaat gggtgtcaga cagtcagact ctctttggcc
    22921 gattttgatt cagatgccgg ttattttggc cctgttccaa gccctatcaa gagttgactt
    22981 tttaaagaca ggtcatttct tatggattaa ccttggtagt gtggatacaa cccttgttct
    23041 tccgatttta gcagcagtat tcaccttttt aagtacttgg ttgtccaaca aagctttgtc
    23101 tgagcgaaat ggcgctacga ctgcgatgat gtatgggatt ccagtcttga tttttatctt
    23161 tgcagtttat gcgccaggtg gagtcgccct atactggaca gtgtctaatg cttatcaagt
    23221 cttgcaaacc tatttcttga ataatccatt caagattatc gcagagcgcg aggccgtagt
    23281 acaggcacaa aaagatttgg aaaatagaaa aagaaaagcc aagaaaaagg ctcagaaaac
    23341 gaaataaata aggaggaatc tggtaatggt agtatttaca ggttcaactg ttgaagaagc
    23401 aatccagaaa ggattgaaag aattagatat tccaagaatg aaggctcata tcaaagtcat
    23461 ttctagggag aaaaaaggct ttcttggtct atttggtaaa aaaccagccc aagtggatat
    23521 tgaagcgatt agtgaaacga ctgttgtcaa agcaaatcaa caggtagtaa aaggcgttcc
    23581 gaaaaaaatc aatgatttga acgagcctgt gaagacggtt agtgaagaaa ccgttgacct
    23641 tggtcatgtg gttgatgcta ttaaaaaaat agaggaagaa ggtcaaggta tttctgatga
    23701 agtcaaggct gaaatcttaa aacatgaaag acatgccagc actatcttag aagaaactgg
    23761 tcacattgag attttaaatg aacttcaaat cgaggaagcg atgagggaag aagcaggcgc
    23821 tgatgacctt gaaactgagc aagatcaaac tgaaaatcaa gacttgaaag agatgggctt
    23881 gaaggtcgag caaagttatg atattgccca ggtggctacg gatgtgactg cttatgttca
    23941 aacgattatt gatgacatgg atgttgaggc tacactttca aatgattata accgtcgtag
    24001 catcaatttg caaattgata ctaacgaacc aggtcgtatt atcggctacc atggtaaagt
    24061 cttgaaggcc ttgcaactgt tggctcaaaa ttatctttac aactgctatt caagaacctt
    24121 ctatatcact attaatgtca atgattatgt tgaacaccgt gcagaagtct tgcagaccta
    24181 tgcgcaaaaa ttggcgattc gtgttttaga agaagggcgc agtcatcaaa cagatccaat
    24241 gtcgaatagt gaacgcaaga ttatccaccg tattatttca cgtatggatg gcgtgaccag
    24301 ttactctgaa ggtgatgagc caaatcgcta tgtcgttgta gatacagaat aagtaaaatc
    24361 agggttgacc tgattttttg ctagctagag gaggttaaac tgatgttgaa taagataaga
    24421 gactatctag acttttctgg tttgcagtac cgtagtcctg ataaagcggg agcagagcga
    24481 gagaagatgc tggcgttccg ccacaaagga caagaggccc gaaaggcttt tacagaactg
    24541 gccaaagcct ttcaagcaag ccatccagaa tggcaactcc aacagactag tcagtggatg
    24601 aatcaggccc agcgtttgag accacatttt tgggtttatc tacagagaga cggacaagtg
    24661 acagaaccta tgatggcctt acgtttgtat gggacatcta ctgactttgg aatttctttg
    24721 gaagtcagtt tcatcgaacg taagaaggat gagcaaacac tgggcaagca gaccaaagtt
    24781 ttagacattc caaccgttaa agggatttat tatctaacct actctaatgg tcaaagtcaa
    24841 cggtgggagg cgaatgaaga aaagcgtcgt actttacgcg agaaggtgag aagtcaagaa
    24901 gttcgaaaag ttttagtgaa ggtagatgtt cctatgacag aaaattcgtc tgaagaagaa
    24961 atcgtagaag gcttattgaa gtcttattct aaaattcttc cctattatct agctacgaga
    25021 aaataagata atttgtaaaa catcataaat catacagtcc aagagtgaac agtccgctgt
    25081 gtaattcttg gtctttttgt ttgcgctttc gcattatata ataaacttac aaaaacaatt
    25141 caaaaggaga acaattatgg aagtcgtttc aagtgttcta aattggtttt ctagcaatat
    25201 tttgcagaat cccgcatttt tcgtaggttt attggtgttg ataggatatg cacttttgaa
    25261 aaaacctgcc catgacgttt tttcagggtt tgttaaagca acagtagggt atatgttgct
    25321 taacgtgggt gctggtggtt tggttacaac ctttcgtcca atcttagcag ctcttaacta
    25381 caaattccaa attggtgcag cggttatcga cccttacttt ggacttgctg cagcaaacaa
    25441 caaaattgca gcagagtttc cagattttgt tggaactgca actacagctc tattgattgg
    25501 ttttggaata aatatcttgc tcgtagctct tcgaaagatt acgaaggtaa gaaccctctt
    25561 tattactggt cacatcatgg tacaacaagc tgcaacagta tctcttatgg ttctattctt
    25621 agtaccacaa ttgcgcaatg cttacggtac agcagcgatt ggtatcatct gtggacttta
    25681 ctgggcagtt agttcaaata tgactgttga ggcaactcaa cgcttgactg gtggtggcgg
    25741 atttgcgatt ggtcaccaac agcaatttgc aatctggttt gtagataaag tagcaggacg
    25801 ctttggtaag aaataagaaa gtttagacaa tcttaaatta cctaagttcc tctcaatctt
    25861 ccacgataca gttgttgcat ctgctacctt gatgctcgta ttcttcggag ccattctttt
    25921 aatcttgggt ccagacatta tgtctaataa agaagtcatc acttcaggaa ctctattcaa
    25981 tcctgctaaa caagatttct ttatgtacat tatccaaaca gcctttacct tctcagttta
    26041 cttgttcgtt ttgatgcaag gtgtccgaat gttcgtatct gagttgacaa acgccttcca
    26101 aggtatttca aacaaattgt tgccaggttc attcccagcg gttgacgttg cagcttctta
    26161 tggatttggt tctccaaatg ctgtcctgtc aggatttatc tttggtttga ttggtcaatt
    26221 gattacaatt gttttgctca tcgtctttaa aaatccgatt cttattatta caggatttgt
    26281 accagtgttc tttgacaatg cagccattgc ggtctacgct gataaacgcg gcggatggaa
    26341 agcggctgtt atcctttcct ttatatcagg tgtccttcaa gttgctctag gagctctttg
    26401 tgtggccctt ctcgatttgg catcttatgg tggctaccat ggaaatatcg actttgaatt
    26461 cccatggctt ggatttggat atatcttcaa ataccttggt attgttggtt atgtacttgt
    26521 gtgtctcttc ttgcttgtta ttcctcaact tcaatttgcc aaagcaaaag ataaagagaa
    26581 atattacaac ggtgaagttc aagaagaagc ttagtatcta gaaaaggaga aataaaatgg
    26641 ttaaagtatt agcagcgtgc ggaaatggaa tgggttcatc aatggttatc aagatgaagg
    26701 ttgaaaatgc tctccgtaag cttaatcaaa cagattttac agtcaattca tgcagtgtcg
    26761 gtgaagctaa aggtttagca gtaggatatg acatcgtaat cgcttctctt catttgattc
    26821 aagaattgga agggcgaact aatgggaagt taattgggct tgataacttg atggatgata
    26881 aagaaatcac cgaaaaactc agtcaagcac tacagtaaaa ggttggaggg ggctggacag
    26941 aaactgagag ttatcgtttc tgtccttctc cctctttaaa taaaggaggc agatatgaat
    27001 ttaaaacaag ctttaattga caacgactcg atccgactag gtttagaggc taacgattgg
    27061 aaagaagcag tcaaggtagc agtagatccc ttgattgaaa gtggggcaat tttgccagag
    27121 tattacgatg ctatcattga atcgactgaa gagtatgggc cttactatat cttgatgcca
    27181 ggtatggcta tgccccacgc tagacctgaa gctggtgtgc aaagtgatgc cttttcattg
    27241 attaccttac aaaatcctgt tgtattttca gatgggaaag aggtatctgt tttgttggca
    27301 ctagcagcaa caagttcaaa aattcacaca agtgtagcca ttccacaaat tattgccctg
    27361 tttgaattag aagattctat tgcacgttta caggcttgcc agactaaaga agatgtcttg
    27421 gctatgattg aagaatctaa ggatagccct tatctcgaag gattggattt ggaaagttag
    27481 aaagaggaat aaagaaatga caaaaagaat acctaattta caagttgcat tagaccattc
    27541 agacttgcaa ggagcgatta aagcagctgt ttctgttggt caggaagtag atattatcga
    27601 agctggaact gtttgcttgc ttcaagttgg aagtgaactg gctgaagtct tgcgtagcct
    27661 tttcccagat aagattattg tggcagacac aaaatgtgct gatgctggtg gaacagttgc
    27721 taaaaataat gcggttcgtg gagcagactg gatgacttgt atctgttgtg caaccatccc
    27781 tactatggaa gcagctctaa aggctatcaa gactgaacga ggcgaacgag gcgaaatcca
    27841 gatcgagctt tatggcgatt ggacttttga acaagctcag ctttggctag atgcaggtat
    27901 ctcacaagct atttatcacc aatctcgtga tgctcttctt gctggtgaaa cttggggtga
    27961 aaaagacctt aataaggtta aaaaactcat tgacatgggc ttccgtgtat ctgtaacagg
    28021 tggtctagat gtagatactc tcaaactctt tgaaggtgtt gatgtcttta cctttatcgc
    28081 aggtcgtgga attacagagg ctgcggatcc agcaggagca gcgcgtgcct tcaaggatga
    28141 aatcaaacga atttgggggt aaatcatggt acgtccaatt ggaatttatg aaaaggcaac
    28201 cccaacacac tttacttggc tagaacgttt aaattttgcc aaggagttag gctttgattt
    28261 tgtcgagatg tctattgacg aacgtgacga gcgtttagca agacttgact ggagtaagga
    28321 agaacgcttg gaagttgtca aagaaatcta tgaaactggt gttcgtattc cttctatctg
    28381 tttttcaggc catcgtcgct acccattggg atcaaaagat ccagttctag aggaaaaatc
    28441 tctagaactc atgaaaaaat gtatcgaatt agctcaagac ttgggagttc gtacgattca
    28501 attagctggt tacgatgttt actatgagga aaagtcaccc cagacacgcc aacgttttat
    28561 caaaaatttg agaaaagcct gtgactgggc tgaagaagct caggtggtac ttgctattga
    28621 aattatggat gatcctttca tcagtagcat cgaaaaatat ttggctatag aaaaagagat
    28681 tgactctccc ttcctctttg tatatccaga tattggtaat gtgtctgcat ggcataatga
    28741 tatctatagt gagttttatc ttggtcatca tgccatcgca gctctccatc tcaaggatac
    28801 ttatgcagtg acagaaagtt caaagggcca gttccgagat gtacctttcg ggcaaggttg
    28861 tgtcaaatgg gaagaagctt tcgatatttt aaaggaaacc aattataatg gacctttcct
    28921 aatcgaaatg tggtctgaaa attgtgaaac agtagaagaa acacgcgcag ccattcaaga
    28981 ggcgcaagct tttctctatc cactcattaa gaaagcaggt ttgatgtaag atgaatcaag
    29041 taatcaatgc tatgcgtaaa cgagtctgtg atgccaatca atcattgcca aaacatggac
    29101 ttgtcaaatt tacctggggg aatgtatctg aagtcaatcg cgaactcggt gtcattgtta
    29161 tcaaaccatc aggcgtggat tatgacgaat tgacacctga aaacatggta gtgactgatc
    29221 tagatggtaa gatcctagaa ggggatttaa gaccatcttc cgacctccca actcatgtgc
    29281 aattatataa gacttggtca gaaattggta gtgtggttca cacccattcg acagaagctg
    29341 ttggttgggc tcaggcaggt cgtgatattc ctttctacgg aacaacccat gcagattatt
    29401 tctacggttc aatcccttgc gcccgtagtt tgaccaagga cgaagtagaa gtggcctatg
    29461 aaaaagatac tggcctggtt atcgtagaag agtttgaaca tcgcggactt aacccggttg
    29521 aagtaccagg aattgttgta cgcaatcacg gtccattcac ctggggcaaa aatccagaga
    29581 atgctgttta tcactctgtc gtactagagg aagtatcaaa gatgaatcgc tttacagaac
    29641 aaatcaatcc aagagttgga cctgctcccc agtacatact agaaaaacac taccaacgta
    29701 aacatggacc aaatgcttat tatggtcaaa agtaagaacg atgaaggaga agaaaaagat
    29761 aaatttagct cctcttttta catttgattt ttattgagag taaagttgga gttgaagtaa
    29821 ttttgaaaga ttttttagaa atagcgcttg atatatatat ggtaaaataa aaagaattgc
    29881 tgtgatatca atagatttgg gggatttttt aatatggtac tggataaggc aagttgtgat
    29941 ttgcttcaat atttgatgga tcaagaaacg tccaaaacga ttatggcgat ttcgaaagat
    30001 ttgaaagagt caagaaggaa aatttattat cacattgaca aaatcaatgc tgctctggtt
    30061 gacgaggcgc ttcacatcat tagtattcca cgaattggta ttcacttaac ggaagagcag
    30121 agagatgctt gttgtaaact attatcggaa gtagattcgt acgattatat catgagtgcg
    30181 catgaacgta tgatgataat gttactatgg ataggtattt ctaaagaacg tattacgatt
    30241 gaaaaattga tagagttaac agaggtatct aggaatactg ttctcaatga tttgaatagc
    30301 attcgttatc aactaacttt ggaacaatat caggtgacct tgcaagtgag caagtcacag
    30361 ggataccacc ttcatgccca ccctcttaat aaaattcagt atcttcaatc gcttctatat
    30421 catattttta tggaagaaaa tgccactttt gtatctattt tagaagataa gatgaaagag
    30481 aggttagatg atgagtgttt gctttctgtt gaaatgaacc aattttttaa ggaacaggtt
    30541 cctttagttg aacaagattt agggaagaaa ataaatcatc atgaaataac ttttatgttg
    30601 caggttctac cttatttgct gttaagctgt cataatgttg aacagtatca agaaagacat
    30661 caggatatag agaaagagtt ttctttgata agaaaaagaa tagagtatca ggtgtctaag
    30721 aaattaggag aacggttgtt tcaaaagttt gaaatttctt tgtcaggact tgaagtttct
    30781 cttgtagctg ttctcctcct ctcctatcgt aaagatttgg atattcatgc agaaagtgat
    30841 gattttcggc aattaaaact tgctttagaa gaatttatct ggtattttga atcacaaatc
    30901 cgaatggaga ttgagaacaa ggatgatttg ttacgaaatt tgatgatcca ctgtaaagcc
    30961 ttgttattta gaaagactta cggtattttt tctaaaaatc ctctaacaaa acaaattcga
    31021 tccaagtatg gagaattatt tttagtcact agaaaatctg cggaaatttt agaaggagca
    31081 tggtttattc ggctaacaga cgatgatatt gcctatttga cgattcatat tggaggattt
    31141 ttaaagtata caccatcgtc tcaaaaaaat atgaaaaaag tttatctcgt ttgtgatgaa
    31201 ggtgttgcgg tttcgagact tttgctgaaa caatgcaaac tttattttcc aaatgagcaa
    31261 attgacactg tatttacaac agaacaattt aagagtgtgg aagatattgc acaagttgat
    31321 gtagtgatta ctactaatga tgatttggat agcagatttc cgattttaag ggttaatcct
    31381 atccttgaag cagaagatat tttgaaaatg ctagactatc ttaaacacaa tatatttcgt
    31441 aataagagca aaagtttcag tgaaaatctt tctagtctta tttcgtctta tattgtagac
    31501 agcaagttgg ctagtaagtt ccaagaagag gttcaaacac ttataaatca agaaatagta
    31561 gttcaagctt ttttggaaga tatttgaagg acagtccaat gatgaacaca aacctgtgtt
    31621 tttcttggtc ttttttagtg ttttgaaggg tggtatacta atctcaaaga taacaattat
    31681 atccaaagga ggcaacatat gccaaacgtc aaagaaatta caagagagtc atggatttta
    31741 gccactttcc cagagtgggg aacatggttg aacgaagaaa tcgaagaaga agtcgtacct
    31801 gaaggcaact ttgccatgtg gtggctaggc aactgtggta cttggattaa gacaccagct
    31861 ggtgctaacg ttgtcatgga cctttggtca aaccgtggaa aatcaaccaa aaaagtgaaa
    31921 gatatggttc gtgggcacca aatggcaaat atggcaggtg ttcgtaagtt gcaaccaaac
    31981 ttgcgtgttc agccaatggt tatcgatcca tttgctatca acgaactaga ctattactta
    32041 gtttcacact tccacagtga tcatatcgac ccatacacag ctgcagcaat tctcaacaat
    32101 cctaagttag agcatgttaa gtttatcggt ccttaccact gtggacgaat ctgggaagga
    32161 tggggtgttc caaaagaacg tatcatcgtt gttaaaccag gtgacactat cgaattaaaa
    32221 gatatgaaga ttcatgcagt agaatcattt gaccgtactt gcttggtaac tctcccagtg
    32281 aacggtgctg atgagacagg cggtgaactt gctggcttgg ctgttacaga tgaagaaatg
    32341 gctcaaaagg ctgttaacta tatctttgaa acaccaggtg gaaccatcta tcatggtgca
    32401 gattctcact tctcaaacta ttttgcaaaa catggtaaag actttaaaat tgatgttgct
    32461 ttgaataact atggtgaaaa tccggtaggt atccaagaca aaatgacatc tatcgacctt
    32521 cttcgtatgg cagaaaatct gcgtaccaaa gtcattatcc cagttcacta tgatatctgg
    32581 tctaacttca tggcttctac taatgagatt ctagaacttt ggaaaatgcg aaaagatcgc
    32641 ttgcaatacg atttccatcc atttatctgg gaagttggcg gtaagtacac ttatcctcaa
    32701 gatcaacact tagtagaata ccatcatcca cgtggttttg atgattgttt tgaacaagac
    32761 tctaacattc aatttaaagc tttgctataa tataaaaata ttctttggag gttatccgta
    32821 tgttgcatga tacggataat tttcatataa tagtaaaata gaatgtgtga ttcaataatc
    32881 acctcaatag aaaggaaatt ctatgtcaaa tctatctgtt aatgcaattc gttttctagg
    32941 tattgacgcc attaataaag ccaactcagg tcatccaggt gtggttatgg gagcggctcc
    33001 gatggcttac agcctcttta caaaacaact tcatatcaat ccagctcaac caaactggat
    33061 taaccgcgac cgctttattc tttcagcagg tcatggttca atgctccttt atgctcttct
    33121 tcacctttct ggttttgaag atgtcagcat ggatgagatt aagagtttcc gtcaatgggg
    33181 ttcaaaaaca ccaggtcacc cagaatttgg tcatacggca gggattgatg ctacgacagg
    33241 tcctctaggg caagggattt caactgctac tggttttgcc caagcagaac gtttcttggc
    33301 agccaaatat aaccgtgaag gctacaatat ctttgaccac tatacttacg ttatctgtgg
    33361 agacggagac ttgatggaag gtgtctcaag cgaggcagct tcatacgcag gtttgcaaaa
    33421 acttgataag ttggttgttc tttatgattc aaatgatatc aacttggatg gtgagacaaa
    33481 ggattccttt acagaaagtg ttcgtgaccg ttacaatgcc tacggttggc atactgcctt
    33541 ggttgaaaat ggaacagact tggaagccat ccatgctgct atcgaaacag caaaagcttc
    33601 aggcaagcca tctttgattg aagtgaagac ggttattgga tacggttctc caaacaaaca
    33661 aggaactaat gctgtacacg gcgcccctct tggagcagat gaaactgcat caactcgtca
    33721 agccctcggt tgggactacg aaccatttga aattccagaa caagtatatg ctgatttcaa
    33781 agaacatgtt gcagaccgtg gcgcatcagc ttatcaagct tggactaaat tagttgcaga
    33841 ttataaagaa gctcatccag aactggctgc agaagtagaa gccatcatcg acggacgtga
    33901 tccagtcgaa gtgactccag cagacttccc agctttagaa aatggttttt ctcaagcaac
    33961 tcgtaattca agtcaagatg ccttgaatgt tgtggcagct aaattaccaa ccttcctagg
    34021 tggatcagct gaccttgctc actcaaacat gacttatatc aagacggatg gacttcaaga
    34081 cgataccaat cgcttgaatc gtaacattca gtttggtgtt cgtgaatttg caatgggaac
    34141 aatcttgaac gggatggccc ttcatggtgg acttcgtgta tacggtggaa ctttcttcgt
    34201 cttctctgac tatgtgaagg cagctgtccg cttgtcagcc ttacaaggac ttcctgtgac
    34261 ttatgtcttt acccatgatt caatcgcagt tggggaagat ggtccgactc acgaaccagt
    34321 tgagcattta gcaggtcttc gtgctatgcc aaatctaaat gttttccgtc cagcagatgc
    34381 gcgtgaaacg caagcagctt ggtaccttgc agtgacaagt gagaaaacac caactgccct
    34441 tgtcttgaca cgtcaaaact tgactgttga agatggaaca gacttcgaca aggttgctaa
    34501 aggtgcttat gttgtatatg aaaatgcagc cgactttgat accatcttga ttgcgacagg
    34561 ttcagaggtt aatcttgctg tctcagctgc taaagaattg gctagtcaag gcgaaaaaat
    34621 ccgcgtagtc agcatgccat ctacagatgt ctttgataaa caagatgcag cttacaagga
    34681 agagattctt ccaaatgcag tccgccgtcg tgttgcagtc gaaatgggtg caagtcaaaa
    34741 ctggtacaaa tatgttggtc tcgatggtgc cgttctaggt attgatacct tcggagcctc
    34801 tgccccagca ccaaaagtat tggcagaata tggctttact gtagaaaatc ttgtaaaagt
    34861 tgttcgaaac ttgaaataat cctaaaaatc agggcgtaag ctctggtttt tcttaccaga
    34921 aaagtaaggt acaatcttgt aaaagtagct gaaatttgat atagtagtcc tatgtaaaag
    34981 acaaaggaga aaacaatgaa tccaaatatt acttttttaa tcatgcttgt aggtatgatg
    35041 gccttgatgt tctttatgca acgttctcaa aagaaacaag ctcaaaagcg tatggaaagc
    35101 ttaaataaac tacaaaaagg ctatgaagtg attacaatcg gtggacttta tggaacagtc
    35161 gatgaagtag atacggagaa gggaacaata gttcttgacg tagatggagt ttacttgact
    35221 tttgaactag ctgctatcaa gacagtatta ccgctgaaag aaacagcttc actagaaggc
    35281 gcaattgaaa aataagacgg gatcacgaac tcccgttttt ctataaaaga aaggaaatgg
    35341 gatgaaaaaa ttagtctttg tctgtctggg aaatatttgc cgtagcccta tggccgagtt
    35401 tgttatgaaa tcaatgacag ataactacga aatccaaagt cgagcaactt cctcttggga
    35461 acatggcaat ccgattcata aggggactca gggaattttt caagagtatg agattcctta
    35521 tgacaagaac aagacatcgc ttcagattag taaggaagat tttgaagcct ttgattatat
    35581 tatcggaatg gacgcttcaa atatttctga cttacgtcag atgtgtccag tagactgtca
    35641 agataagatt tactcatttt catctgaaag tgttccagac ccttggtata caggagattt
    35701 tgaagaaacc tatcgacgtg ttcaagaggg ctgtcaagct tggttagaac gtttagaaaa
    35761 ggagagttaa ggtggaaaat cttacgaatt tttacgaaaa gtatcgtgtc tatctgactc
    35821 gtccacgatt agagcttttg gcagtagtta ccattgtttt ctgtgctgta ctcgtctttt
    35881 ttctaaatat tccaggaaaa ggtgtcttaa aactcgataa tggaacgatt gtttatgatg
    35941 gcagtcttgt ccgtggtaaa atgaatggtc aaggtaccat taccttccaa aatggagacc
    36001 aatatacagg tggcttcaac aatggagcct tcaacggaaa aggtaccttt caatctaaag
    36061 aaggctggac ctacgaaggt gattttgtaa atggtcaggc tgaaggaaaa gggaaactaa
    36121 caacagaaca agaagtcgtt tatgaaggaa cttttaaaca aggcgttttt caacaaaaat
    36181 aaagcctcct tatcaaagga ggtattatta gaattacaag gtaagcgctt acctgtaaat
    36241 ccctttcttt ccaaatccct cttccaagca agtttgtgaa ataaaaaata tttgaaataa
    36301 atttcacaaa cttcaaagat aaaacctgat aagaaaagaa aatgagaaaa gtttcacaag
    36361 agtttaaaaa ttctttgtga aatgtttatg aaactgttta caaagttgaa ataatacgtt
    36421 ataataaact tgtgaaaaaa ttaacaaagg atatcgatcc ttgaaagcta tggaggaaaa
    36481 tatggctgat aaaaaaactg tgacaccaga ggaaaagaaa ctcgttgctg aaaaacacgt
    36541 agatgagttg gttcaaaaag ctctagttgc ccttgaagaa atgcgtaaat tggatcaaga
    36601 gcaagttgac tacatcgttg ccaaagcatc agtagcagct ttggatgccc acggagaatt
    36661 ggctttacat gcctttgaag aaacaggacg tggtgtattt gaagataaag caactaagaa
    36721 cttgtttgcc tgtgaacacg tagtaaacaa catgcgtcac actaagacag ttggcgttat
    36781 cgaagaagac gatgtaacag gattgactct tattgctgaa ccagttggtg ttgtttgtgg
    36841 tattactcca acaacaaacc caacatcaac agcaatcttc aaatcattga tttcattgaa
    36901 gacacgtaac ccaatcgtct ttgccttcca tccatcagca caagaatcat ctgctcatgc
    36961 agctcgtatc gtccgcgatg cagctatcgc agctggtgct cctgaaaact gtgtgcaatg
    37021 gattactcaa ccatctatgg aagcaacaag tgcccttatg aaccacgaag gtgttgcgac
    37081 aatccttgca acaggtggta atgccatggt taaggcggct tattcatgtg gtaaaccagc
    37141 tcttggggta ggtgccggaa acgttccagc ttatgttgaa aaatcagcaa acattcgtca
    37201 agcagcacac gatatcgtca tgtctaaatc atttgataac ggtatggtct gtgcatctga
    37261 acaagcagtt atcattgata aagaaattta tgatgaattt gtagcagagt tcaaatctta
    37321 ccacacttac tttgtaaaca aaaaagaaaa agctcttctt gaagagttct gcttcggcgt
    37381 caaagcaaac agcaaaaact gtgctggtgc aaaattgaac gctgacatcg ttggtaaacc
    37441 agcaacttgg attgcagaac aagcaggatt tacagttcca gaaggaacaa acattcttgc
    37501 tgcagaatgt aaagaagttg gcgaaaatga gccattgact cgtgaaaaat tgtcaccagt
    37561 tattgcagtt ttgaaatctg aaagccgtga agatggtatt actaaggctc gtcaaatggt
    37621 tgaatttaac ggtcttggac actcagcagc tatccacaca gctgacgaag aattgactaa
    37681 agaatttggt aaagctgtta aagctattcg tgttatctgt aactcacctt ctacttttgg
    37741 tggtatcggg gacgtttaca atgccttctt gccatcattg acacttggat gtggttctta
    37801 cggacgcaac tcagttgggg ataacgttag tgccattaac ctcttgaata tcaaaaaagt
    37861 cggaagacgg agaaataaca tgcaatggat gaaacttcct tcaaaaacat actttgaacg
    37921 tgattcaatt caataccttc aaaaatgtcg tgacgttgaa cgtgtcatga tcgttactga
    37981 ccatgccatg gtagagcttg gtttccttga tcgtatcatc gaacaactgg accttcgtcg
    38041 caataaggtt gtttaccaaa tctttgcgga tgtagaaccg gatccagata tcacaactgt
    38101 aaaccgtggt actgagatta tgcgtgcctt caaaccagat accatcatcg cactcggtgg
    38161 tgggtctcca atggatgctg ccaaagtaat gtggctcttc tacgagcaac cagaagtgga
    38221 cttccgtgac cttgtccaaa aattcatgga tatccgtaaa cgtgccttca agttcccatt
    38281 gcttggtaag aagactaaat tcatcgcgat tccaactaca tctggtacag gatctgaagt
    38341 aacaccattt gccgttatct ctgataaagc aaacaaccgt aaatacccaa tcgctgacta
    38401 ctcattgaca ccaactgtgg caatcgtaga tcctgctttg gtattgacag ttccaggatt
    38461 tgttgctgct gatactggta tggacgtatt gactcacgcg acagaagcat acgtatcaca
    38521 aatggctagt gactacactg atggtttagc acttcaagcc attaaattgg tctttgaaaa
    38581 tctcgaaagc tcagttaaga atgcagactt ccactcacgt gagaaaatgc ataacgcttc
    38641 aacaatcgct ggtatggcct ttgccaatgc cttcctaggt atttctcact caatggccca
    38701 taagattggt gcgcaattcc acacaatcca cggtcgtaca aatgctatct tgcttccata
    38761 cgttatccgt tacaacggta cacgtccagc taagacagca acatggccta agtacaacta
    38821 ctaccgtgca gatgaaaaat accaagatat cgcacgcatg cttggacttc cagcttctac
    38881 tccagaagaa ggggttgaat cttacgcaaa agctgtctac gaactcggtg aacgtattgg
    38941 gatccaaatg aattttagag accaaggaat tgacgaaaaa gaatggaaag aacattctcg
    39001 tgaattagcc ttcctggctt atgaagacca atgttcacca gctaacccac gtcttccaat
    39061 ggtagaccat atgcaagaaa tcatcgaaga tgcatactat ggctacaaag aaagaccagg
    39121 acgccgtaaa taattgttta tcagtctaga agcaagacaa aaactcaatt tgagggaaag
    39181 atccagtaat ttttctatga taaaaggcat cctatcaagg tttttgaaca cctgatagga
    39241 tgccttttta tgatattgag gcctttttgc cctttttgaa aaactagaat agaaacaaaa
    39301 tatataatag attgaaacta gagtag
//
LOCUS       DAVMCN010000013        38085 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVMCN010000013 DAVMCN010000000
VERSION     DAVMCN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.013"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(657..1229)
                     /locus_tag="VYP85_000837"
     CDS             complement(657..1229)
                     /locus_tag="VYP85_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881377.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
     gene            complement(1850..2698)
                     /locus_tag="VYP85_000838"
     CDS             complement(1850..2698)
                     /locus_tag="VYP85_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1881378.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            2850..3128
                     /locus_tag="VYP85_000839"
     CDS             2850..3128
                     /locus_tag="VYP85_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881379.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            3130..5193
                     /locus_tag="VYP85_000840"
     CDS             3130..5193
                     /locus_tag="VYP85_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1881380.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(5271..6527)
                     /locus_tag="VYP85_000841"
     CDS             complement(5271..6527)
                     /locus_tag="VYP85_000841"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1881381.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            6669..9134
                     /locus_tag="VYP85_000842"
     CDS             6669..9134
                     /locus_tag="VYP85_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1881382.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALVPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            9199..10110
                     /locus_tag="VYP85_000843"
     CDS             9199..10110
                     /locus_tag="VYP85_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1881383.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            10340..11038
                     /gene="dapD"
                     /locus_tag="VYP85_000844"
     CDS             10340..11038
                     /gene="dapD"
                     /locus_tag="VYP85_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1881384.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            11106..12236
                     /locus_tag="VYP85_000845"
     CDS             11106..12236
                     /locus_tag="VYP85_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1881385.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            12248..12787
                     /locus_tag="VYP85_000846"
     CDS             12248..12787
                     /locus_tag="VYP85_000846"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1881386.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            12771..13448
                     /locus_tag="VYP85_000847"
     CDS             12771..13448
                     /locus_tag="VYP85_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1881387.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(13515..14414)
                     /gene="galU"
                     /locus_tag="VYP85_000848"
     CDS             complement(13515..14414)
                     /gene="galU"
                     /locus_tag="VYP85_000848"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1881388.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKAFAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(14436..15452)
                     /locus_tag="VYP85_000849"
     CDS             complement(14436..15452)
                     /locus_tag="VYP85_000849"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1881389.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKPYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            15664..16044
                     /locus_tag="VYP85_000850"
     CDS             15664..16044
                     /locus_tag="VYP85_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1881390.1"
                     /translation="MRKFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(16218..16643)
                     /locus_tag="VYP85_000851"
     CDS             complement(16218..16643)
                     /locus_tag="VYP85_000851"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1881391.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYASSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(16711..17361)
                     /gene="phoU"
                     /locus_tag="VYP85_000852"
     CDS             complement(16711..17361)
                     /gene="phoU"
                     /locus_tag="VYP85_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1881392.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(17376..18128)
                     /gene="pstB"
                     /locus_tag="VYP85_000853"
     CDS             complement(17376..18128)
                     /gene="pstB"
                     /locus_tag="VYP85_000853"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1881393.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(18130..18945)
                     /gene="pstA"
                     /locus_tag="VYP85_000854"
     CDS             complement(18130..18945)
                     /gene="pstA"
                     /locus_tag="VYP85_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1881394.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(18938..19801)
                     /gene="pstC"
                     /locus_tag="VYP85_000855"
     CDS             complement(18938..19801)
                     /gene="pstC"
                     /locus_tag="VYP85_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1881395.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(19919..20794)
                     /locus_tag="VYP85_000856"
     CDS             complement(19919..20794)
                     /locus_tag="VYP85_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1881396.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(20961..22292)
                     /locus_tag="VYP85_000857"
     CDS             complement(20961..22292)
                     /locus_tag="VYP85_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1881397.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(22293..23000)
                     /locus_tag="VYP85_000858"
     CDS             complement(22293..23000)
                     /locus_tag="VYP85_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881398.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(23084..23386)
                     /locus_tag="VYP85_000859"
     CDS             complement(23084..23386)
                     /locus_tag="VYP85_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1881399.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(23373..23594)
                     /locus_tag="VYP85_000860"
     CDS             complement(23373..23594)
                     /locus_tag="VYP85_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1881400.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            23556..24113
                     /locus_tag="VYP85_000861"
                     /pseudo
     CDS             23556..24113
                     /locus_tag="VYP85_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(24428..26119)
                     /locus_tag="VYP85_000862"
     CDS             complement(24428..26119)
                     /locus_tag="VYP85_000862"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1881401.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            26255..26701
                     /gene="argR"
                     /locus_tag="VYP85_000863"
     CDS             26255..26701
                     /gene="argR"
                     /locus_tag="VYP85_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1881402.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            26752..29286
                     /gene="mutS"
                     /locus_tag="VYP85_000864"
     CDS             26752..29286
                     /gene="mutS"
                     /locus_tag="VYP85_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1881403.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            29433..31127
                     /gene="patA"
                     /locus_tag="VYP85_000865"
     CDS             29433..31127
                     /gene="patA"
                     /locus_tag="VYP85_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1881404.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMIQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKNVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(31445..31708)
                     /locus_tag="VYP85_000866"
                     /pseudo
     CDS             complement(31445..31708)
                     /locus_tag="VYP85_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            31902..33668
                     /gene="patB"
                     /locus_tag="VYP85_000867"
     CDS             31902..33668
                     /gene="patB"
                     /locus_tag="VYP85_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1881405.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            33807..34496
                     /locus_tag="VYP85_000868"
     CDS             33807..34496
                     /locus_tag="VYP85_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1881406.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKHLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            34500..34679
                     /locus_tag="VYP85_000869"
     CDS             34500..34679
                     /locus_tag="VYP85_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881407.1"
                     /translation="MEHLVVLFFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            34666..36015
                     /locus_tag="VYP85_000870"
     CDS             34666..36015
                     /locus_tag="VYP85_000870"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1881408.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEKIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            36139..37599
                     /locus_tag="VYP85_000871"
     CDS             36139..37599
                     /locus_tag="VYP85_000871"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1881409.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGTIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            37613..38047
                     /locus_tag="VYP85_000872"
     CDS             37613..38047
                     /locus_tag="VYP85_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1881410.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT        11121 a         7249 c         8264 g        11451 t
ORIGIN      
        1 ttacctttct tgtaataagc ttgttacctg ataagatttt tggaaaaaat aaaaaaattt
       61 ggaaaatagt ttttgcaata ttgacggcag tggcagcatt gtcatttatg tactaagtta
      121 ttttaagaat gtagggaaat aaaccctaca ttttttttag ttttttctgt tttctaaatt
      181 ctatttatcc aagagcttca acatttcttg cttcttcgct tcaagttctg cacgcttttc
      241 ttcgatttcg gcatgttttt tctcgagttc agaacaactt gcatcattgc taaattcttt
      301 tcgccatcag gagatagggt gagtctacat gtctattact cacccaaagc agtcctacaa
      361 agcaggaatt ttctgttact tttttggaaa tagtaacgtt tatacagctt tgacacttcg
      421 tatcaaagcg ccaaacacac tccgagggat ttacagaaag cagaaaagga atgatcttat
      481 accagatcat tccttttctc tctttttctt taagtaatta tatacaatgt acgacgaagt
      541 cgtcattgca atgctgatcc accacctaaa gggaacttta aacaacattg ataagataaa
      601 gaatataaac aacgaaaata cgttataccc aattaatttt attgtatatc tcatgattaa
      661 aagttaatcc ttccgttgtt aggaatggca tcatttttat cccataattg tgctaaataa
      721 atccccggtg ataataaatt catagcgaat tctaaagcaa catcatttac aaaccaacta
      781 cctagatatc tagaaattgc tgaacgaata gcactttttg ctgcatgttt tccttttact
      841 ttaattagat ttgcaaggcc tgcagtagtt cctcctaatg ctaaagctat tgcagtatct
      901 aatagagcac ccatttgatt aactgtaata ccttgccaag ctgctctaaa tggagagtat
      961 gtaggtggga ttgtataatc gccttgtaat tgtcggttaa ttacttcttt gatccattgt
     1021 tgtgagacgt ctggatgaaa agattggatt tcgtttgcaa gtgtattgat ttgttcttct
     1081 gttagagaag tgacaggttg aagttccata tttgtttcaa tttgtgatac ttgttcagaa
     1141 gcgtatacag ctgaaacact tggaatcgct gatacaatta acacaattga cgtcaaaaaa
     1201 accgaaataa atttcattaa tttgttcatg agcttttctc ctttttattt gtatctgctt
     1261 acattttatc atatactgtt attatagtca aaaaaatatg ctattatgtt aaaaaatatt
     1321 tttcaaaata taaatggacg gatttatttt ggattttatt tgttattttg acctgcctct
     1381 atattggtaa ccatgatttg tttactctca atcatcaaga attctctttt cgtggtagcg
     1441 tttggggtct ggtactggcc ttatatcact tattgttcat tgataagttt gtaatttcga
     1501 atcgaaaata aagattagaa ctatgattga ctggctactt ttaatattga ttttggagga
     1561 agattttgtc tctattattt attattttaa atttatctat tttgtacaag atttattctt
     1621 tgagacggga gaaatcgaaa tacttgattt atacggccta tatcatattt ggggtaaatg
     1681 tagtatatgg tattcaatgg ttattaagag aactgatttc aactatttcc ccttaatgtg
     1741 tatggaaact ataacaaaac gcataagatt aaggtttgtg tacctgttct tatgcgtttt
     1801 tataatattg aagattttcg gtaagtttta tacctttggg aagtctagtt tagaatgctt
     1861 tcccaaccaa aatctctgct tcgatggtaa tctctgtcag ttggctccag tcaatcttgc
     1921 tctggtcaac gtgaaagagg agaggagtca tactgagtag ggcttggagt tgttctgctg
     1981 tgatagtctt agtcagagag gcagtttgac tagataggat ggtaaagtgt tcctggaaat
     2041 gctccttgat atcttggtta gaatactcct tgtttgtcag ctggtcctgt actctttgac
     2101 ggatttcttt gaggtgattt tcagttggga taacctttat caagataccg tctttggata
     2161 aaacgcgacg aaattctcca tagttggcag gtgagaagat atcaagcaga atatccatgt
     2221 tagcgtcttt tataggaagt cgtgccaagt cgccaacaaa ccaattgact gcccagttgg
     2281 gttcactttt agcagcgatt tggactgaat ctttggagat gtcaaaggca tagaaagttt
     2341 tttcagagtg actttcttgt agtttgcgag aatagaatcc ttcaccacaa ccgatatcca
     2401 aaattgttgt ggtagttttt gagcttgcaa gcaagtcaga tacagcatct aagatagctt
     2461 ggtaaaagcc ggcttctagg atttgttgac ggttttgaaa attttccttg ttatagttag
     2521 cagattgctt gatttgaggt gctagattga catagccaaa tttcgccaag tcaaaagaat
     2581 gacggttgca gcacttgaaa ttagtctcta acagagtcag attttcttga cagataggac
     2641 aggcaaaggc agtcgcagaa gcaaaacgct gaagtttggg cttgagattt gtattcatag
     2701 tttaagtgta tcaaaagagg caaatgaaag caactttagg aataagtaga tgggagattc
     2761 agtagaaata aaactaattc tccaatttat agaatgaaat tgcttttata tctaaattgc
     2821 tatataataa tgataaggag gaaataagta tgttaaaaga agtattaacc gttgcaaaag
     2881 ttgcgaaaaa atcttcatta tttttgggtg gtgtcgcatt tggtaccctt ggtttgaaaa
     2941 tcttagcaag taaggaagct aaaaaaggtt attctaaagc tttggctaag gcttacaagt
     3001 tgaaagacga gctagatgca tctgtttctg ttgtgaagca acatggagac gatgtcttgc
     3061 aagatgccaa atatttgtac gagcaagaga aaaaagaaga gcaattagat agccttatag
     3121 gtgaataata tgtcttttaa agtgctacat agaggatacc aacatatccg actatcatct
     3181 tctttttcac ttaccttgga tattcaagac tatcttcgtt ccttggcgag agatgaaaag
     3241 gggattgagt ctatccagtt ttacatggat caacagcact ttactctacg cataaaagaa
     3301 ggcttttctg tattagataa tgcagaagcc tttttaaaaa gaattgataa agggaaagtt
     3361 tctgagttga tgactcttcc cattcgtaga gaagagagtg cttattctat tgtttcaggt
     3421 gcagcggtta agcgtgtact ttttcgtagt tttgtgccgt atcctattcg ctatatatgg
     3481 acttgttatc aggctttggg ttatattaga gaagcctatc aaacactagc gcgtaaggaa
     3541 ctaactatgg aagtcttgga ctgttcggct attttattgt ctttgtttat gaaccaatcc
     3601 aagacagcta gcaatatcat gtttatgctt gatttgggga atcatttaga tcagtggtcc
     3661 ttgaaaaaaa ctgcaacaga tttagaacag agtcttcttg caaaagagag cgatgtattc
     3721 ctagtacagg gcgatacggt tgttagtata aagagttccg atgttcaaat aggagatgtc
     3781 ttgatcttat ctcaaggaaa tgaaattctg tttgatgggc aagtagtttc aggtttaggt
     3841 atggtcaacg aaagttcctt gacaggagag agttttccag ttgaaaaaag agagtctgat
     3901 ttggtttgtg caaatacagt attagaaact ggagagttac gcattcgtgt aacagataat
     3961 cagatgaaca gccgtatttt acagctgatt gagttgatga agaaatctga agaaaacaag
     4021 aaaacgaaac aacgctattt catcaagatg gcggataaag tcgtcaaata taatttcttg
     4081 ggggctgggc tgacttacct attgacaggt tctttttcta aggctatttc tttcctattg
     4141 gtcgatttct cctgcgcttt gaaaatctct actcctgtag cttatttgac agttatcaag
     4201 gaggggttga accgtgaaat ggtgattaag gatggagatg ttctggagaa atatctggaa
     4261 gttgatactt tcttgtttga taagacagga acaatcacaa ctagttatcc tatagttgaa
     4321 aaggtgttac cttttggaga ctatagtgag gaagatattc tcagaatcag tgcctgtctt
     4381 gaggaacaca tttatcatcc tattgctaat gccatcgtca agcaagctga gatagaggga
     4441 attgaacatg aggaaatgca tgggaaactc caatatatcg caagcaaggg gatcaaatct
     4501 catatagatg gccaaccagt tcttattggg aattatgtct tgatgcagga tgagcagatt
     4561 catatcagtt cagaacaaaa tgctttaatt gaagagtaca agagtcacta caatctctta
     4621 ttcttggctt atcaaaatga attgattgga atgttctgca ttcatactcc tttgagaaaa
     4681 gaagcaaaaa cagccttgga taaacttaag gcacagggga aaaaattgat tctggcaaca
     4741 ggagacacct tgattaggac agaggaatta gtcaaagatt tgccctttga tcaggtctat
     4801 acagacttga aacctgatgg gaaatttgag ttagtagaga aactgcagaa agcaggtcac
     4861 actattttga tggttggaga tggattgaat gactcagcgg ctttaactct atcagatatc
     4921 ggtgtggtga tgaatgagag tgcagatatt tctaagcaga tgagtgatat cttattgtta
     4981 gataatcgtt tggatttctt ccaagagttg gattcgttat catcatcttt gcaaacactc
     5041 atcaagaaaa atattcaaga taccgttgtc gtaaatagta gtttgattgg ctttggctta
     5101 tttaattggt tcagtccttc aaatctctct atcttacata atctaacaac cttgcgcatt
     5161 gtcttgcgta gcttgtctat taaaaataga tagatgagag ttattaacag caaaaaggag
     5221 ttacctttct cgaggttaac tcctttgttt atagataaat gttgaatagt ttagtaagtc
     5281 aatacaaagt attttttctt cccacgacgg ataacagtca gttcattttc taacttatca
     5341 gcgtcactca agacatagtc aaggtcttgg atgcggtcgc cgtttacgta gatggctccg
     5401 ttttggacgt cttcacgggc ttggcgtttt gagttaacta taccagatga gacgagcagt
     5461 tccacgatat tgttatgttc gtctgcctgt acttggtagt ttggcacacc acgaagtcct
     5521 tgtttgagct ctttgacaga aaggtttttg atgtttcctg caaagagttg ctcagtgatg
     5581 ttaagtgctt ctttgtaggc ttcttctccg tgaacaagtg taacaacttc acgagccaag
     5641 actttttgag ccaagcgttc gtgtggcgct gcttcaaatt gtttacgaat atcttcaatc
     5701 tcatcaagtg acaagaaagt aaagattttc aagaagcgaa cagcgtcagc gtccatcacg
     5761 ttcatccaga attggtacat ttcgtatgga gaagtctttt cgggattgag ccagacggca
     5821 tttccttctg atttaccaaa tttcttacca gttgcatctg tgattagtgg aacagtgata
     5881 acgtgaccag tcttgtccgc cttacgacga agcaattcgg taccagctgt catatttccc
     5941 cactggtcag aaccaccgat ttgaagagtg acattatggt cttggttaag gacgaagaag
     6001 tcgtaccctt gcatgatttg gtaagcgaac tcagtgtaag aaattcctgt ttcgatccgt
     6061 tttttaacag attccttact catcatgtag ttgaccgtga agtattttcc aatatcacgg
     6121 aggaagtcaa tgaagctgat gctgccaaac cagtcgtagt tgttgaccat gacagccttg
     6181 ttttcgccat tttcaaagtc aagaaaacga gaaagttgtc cttggataga cttgacccag
     6241 ccatctactg tgtcttttgt ttggagacta cgttcagcat ctttgaagga cggatctccg
     6301 atgagacctg tagcaccgcc aacgagcgca taaggtttgt gacctgctag ttgcaagcga
     6361 cgacttgtca agattgcgac aaggtggcct aggtgaaggc tgtcagcagt tggatcgtag
     6421 ccagtataat aagaaacttg accttcttct agggctttac gcaaagcttc ttcatcagtc
     6481 gtttgaaata tcaaaccacg ctcttttagc tcatcaaaaa tgtgcatgtg tcttttctcc
     6541 tttttaaaat tattgtttct acctattgta tcacaaactt gggcaatagc ctagcagaat
     6601 agggaagaaa gtggctattt tattgaaaat ttcccttttg tggtataata gatagagtga
     6661 ggaaatccat gcaaaatcaa ttaaatgaat taaaacgaaa aatgctggaa tttttccagc
     6721 aaaaacaaaa aaataaaaaa tcagctagac ctggcaagaa aggttcaagt accaaaaaat
     6781 ctaaaacctt agataagtca gccattttcc cagctatttt actgagtata aaagccttat
     6841 ttaacttact ctttgtactc ggttttctag gaggaatgtt gggagctggg attgctttgg
     6901 ggtacggagt ggccttattt gacaaggttc gggtgcctca gacagaagaa ttggtgaatc
     6961 aggtcaagga catctcttct atttcagaga ttacctattc ggacgggacg gtgattgctt
     7021 ccatagagag tgatttgttg cgcacttcta tctcatctga gcaaatttcg gaaaatctga
     7081 agaaggctat cattgcgaca gaagatgaac actttaaaga acataagggt gtagtaccca
     7141 aggcggtgat tcgtgcgacc ttggggaaat ttgtaggttt gggttcctct agtgggggtt
     7201 caaccttgac ccagcaacta attaaacagc aggtggttgg ggatgcgccg accttggctc
     7261 gtaaggcggc agagattgtg gatgctcttg ccttggaacg cgccatgaat aaagatgaga
     7321 ttttaacgac ctatctcaat gtggctccct ttggccgaaa taataaggga cagaatattg
     7381 caggggctcg gcaagcagct gagggaattt tcggtgtaga tgccagtcag ttgactgttc
     7441 ctcaagcagc atttttagca ggacttccac agagtcccat tacttactct ccttatgaaa
     7501 atactgggga gttgaagagt gatgaagacc tagaaattgg cttaagacgg gctaaggcag
     7561 ttctttacag tatgtatcgt acaggtgcat taagcaaaga cgagtattct cagtacaagg
     7621 attatgacct taaacaggac tttttaccat cgggcactgt tacaggaatt tcacgagact
     7681 atttatactt tacaactttg gcagaagctc aagaacgtat gtatgactat ctagctcaga
     7741 gagacaatgt ctccgctaag gagttgaaaa atgaggcaac tcagaagttt tatcgagatt
     7801 tggcagccaa ggaaattgaa aatggtggtt ataagattac tactaccata gatcagaaaa
     7861 ttcattctgc catgcaaagt gcggttgctg attatggcta tcttttagac gatggaacag
     7921 gtcgtgtaga agtagggaat gtcttgatgg acaaccaaac aggtgctatt ctaggctttg
     7981 taggtggtcg taattatcaa gaaaatcaaa ataatcatgc ctttgatacc aaacgttcgc
     8041 cagcttctac taccaagccc ttgctggcct acggtattgc tattgatcag ggcttgatgg
     8101 gaagtgaaac gattctatct aactatccaa caaactttgc taatggcaat ccgattatgt
     8161 atgctaatag caagggaaca ggaatgatga ccttgggaga agctctgaac tattcatgga
     8221 atatccctgc ttactggacc tatcgtatgc tccgtgaaaa gggtgttgat gtcaagggtt
     8281 atatggaaaa gatgggttac gagattcctg agtacggtat tgagagcttg ccaatgggtg
     8341 gtggtattga agtcacagtt gcccagcata ccaatggcta tcagacctta gctaataatg
     8401 gagtttatca tcagaagcat gtgatttcaa agattgaagc agcagatggt agagtggtgt
     8461 atgagtatca ggataaaccg gttcaagtct attcaaaagc tactgcgacg attatgcagg
     8521 gattgctacg agaagttcta tcctctcgtg tgacaacaac cttcaagtct aacctgactt
     8581 ctttaaatcc tactctggct aatgcagatt ggattgggaa gactggtaca accaaccaag
     8641 acgaaaatat gtggctcatg ctttcgacac ctagattaac cctaggtggc tggattgggc
     8701 atgatgataa tcattcattg tcacgtagag caggttattc taataactct aattacatgg
     8761 ctcatctagt aaatgcgatt cagcaagctt ccccaagcat ttgggggaac gagcgctttg
     8821 ctttagttcc tagtgtagtg aaatcggaag tcttgaaatc aacaggtcaa aaaccaggga
     8881 aggtttctgt tgaaggaaaa gaagtagagg tcacaggttc gactgttacc agctattggg
     8941 ctaataagtc aggagcgcca gcgacaagtt atcgctttgc tattggcgga agtgatgcgg
     9001 attatcagaa tgcttggtct agtattgtgg ggagtctacc aactccatcc agctccagca
     9061 gttcaagtag tagttctagc gatagcagta actcaagtac tacacgacct tcttcttcaa
     9121 gggcgagacg ataattctct aaatgaagtg gccaatcaat ggattgccac ttttttcctt
     9181 tcgtgttaca ataagggtat gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat
     9241 tcgctcctat ccggcttaat atggggaatc tgtggaattt taggagagta cttctttact
     9301 cattatcagg tgtcttcggg ctggattacc tctatgcgtt tgacactggc agggagtctt
     9361 gtactcattt ggtctgcaat acaattaaaa tcgcaagtgc tagatatttg gcgagacaag
     9421 aaaaattacc tgcccttttt agcctatgct attttgggga ttttttcagt tcagtatttt
     9481 ttctatctct gtgtagaata ctcaaatgct acgacagcaa ctattttaca gtttattagc
     9541 cctgtcttta tcctctttta caatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct
     9601 gttttctatg ttttggttgc catgctgggt gtttgcttga tggcgacaaa gggagacctc
     9661 tctcagttat ccatgacgcc gctagctctt ataacaggtt tgctgagtgc catgggtgtt
     9721 atgtttaatg ttatcttgcc ccaacctttt gctaagcgtt atggttttgt tcctacggtt
     9781 gggtggggga tgattttggc aggtttgttt agcaatgtcc tctcgccggt ttatcagctt
     9841 tcctttactc ttgatatttg gagtatcttg atttgcctca ttatcgcttt ctttggaacg
     9901 gcttttgctt ttttcatttc catgaaggct gtgtccttgg tttctccttt ggtggtttcc
     9961 gttatcagtg ccagtgaacc tctctcttct gctctcttga gtgttttgtt cttaggatta
    10021 gtagtggatt ggtccctcct tctagctata gccttgatta ttttacccat gatatttttg
    10081 tctatagaag aagcgaaaga aagtagataa aaagtctttt cttaattcta aaagtgtgct
    10141 atactagaat agtcaataaa acacggggag atagttgtga agagtgtttt taggttgtat
    10201 cggtaggggc ttgcttttac cgacagcacg ttttatctca catccctaaa aaatcatacc
    10261 taaaaacaga caaaaaggtt tcaaatttga ggcctttttt ggtagaatag gtatcattat
    10321 aacgaaccag gaggcaccta tgactgctac aaaaatgaac gctcaagaaa ttatccaatt
    10381 tatcgccaat gctgaaaaga aaaccagtgt caaagtaacc tttgaggggc aactcgcaac
    10441 tgctgtgcct agctctgttg tcaaactagg aaatgtccta ttcggagact ggaaggacgt
    10501 ggctccgctt cttgaaggtt tggtagaaaa tcaagattat gttgtcgagc aagatgctcg
    10561 taattctgca gttcctttgc tagataagcg tgctatcaac gctcgtatcg agccaggtgc
    10621 tattatccgt gaccaggtgg aaattggtga caatgctgtt atcatgatgg gagctgttat
    10681 caatatcggt gctgaaatcg gtgctggaac catgattgac atgggtgcca tccttggtgg
    10741 ccgtgccatc gttggaaaaa atagccacgt tggtgcaggt gcagttttgg caggtgtgat
    10801 tgagccagct agtgctgaac cagtccgtgt cggagacaat gttcttatcg gtgctaatgc
    10861 agtggttatc gaaggagtcc aaatcggtag tggttcagtt gtcgcagcag gagctattgt
    10921 tacccaagat gtcccagaaa acgtggtagt agcaggtgtt ccagctcgta tcatcaaaga
    10981 aattgatgcc caaactcaac aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt
    11041 gtaaaagtaa aaaagaggcg gaaccctttt tccagcctct ttctgctata tcggaggaca
    11101 gatagatgtt agatttgatt cagactagac gagatttaca ccagatacca gagattggct
    11161 tggaggagtt caagactcag gcttatttgc tggatgtgat tgagaaattg actacgggca
    11221 aggattttgt tcaaattcgt acttggcgga cagggatttt ggtctacctg cagggaagtc
    11281 agccggagcg aaccattggt tggcggacag atattgatgg cctgcctatc gtcgaacaaa
    11341 caggtctacc ttttgcttct caacaccaag gtcgcatgca tgcctgtggc catgattttc
    11401 atatgaccat tgccttaggc tgtcttgagc gcgcccttga ggagcaacct aaaaataatc
    11461 tgctctttct atttcagcct gctgaagaaa atgaagctgg tggtatgctc atgtatgagg
    11521 ctggtgcttt tggagattgg ttgccaaacc aattctatgg tctccatgtt cgtccagatt
    11581 tgaaagtcgg ccagattgcg actaatactc atacactctt tgcaggaact tgcgaggtga
    11641 agatccgttt caaaggcaaa ggtggccacg cagcttttcc tcatgaagcc aatgacgcct
    11701 tggtggcggc tagttacttt gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc
    11761 caatcgaggg agcagtggtg accttcggcg tttttcaagc tggaaccacc aacaatgtca
    11821 tcacagacac agctttttta catggaacta ttcgtgcctt gacacaggac atgagtctct
    11881 tggtgcaaaa gagggtaaaa acagttgcag aaggggttgc agctgccttt gatatggaag
    11941 tcgaagtgga actcaaacaa ggtggatacc tacctgttga gaacaatcca gccttggcgc
    12001 gtgaactgat ggacttcttt gacgagaaag acggaatcga gttgattgat atcgaacctg
    12061 ctatgacagg cgaggacttt ggttatctcc tttcaaaggt tgatggcgtg atgttttggc
    12121 taggtatcga tagtccctac gctcttcatc accctcaaat gagtcctaag gaagaagtct
    12181 tagctattgg ggtggctgcg gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg
    12241 cttgtctatg aaatcggaat tacgcaagca agtcttgcat gaaatgaagg ctttatctca
    12301 agaacaaaaa caggctatag accaagcttt aaccgagcga attttacaac acccctttta
    12361 tcaagaagcc aaggtcatcg caacctacct ctctttttct catgagtttc aaacgcggga
    12421 actgattgag caggcgctga aggacggcaa gaaggtttta atacccaaaa cttatcccaa
    12481 ggggcgcatg gactttgtag tctatgatct gcagcagttg gtaaaaactg cctttgcctt
    12541 actggagcca cagggagatt tggaagtggt ggatgtatct cagattgatt tgattcatgt
    12601 tcctggcctg gcttttacga cggatggata tcggattgga tatggtggag gttattatga
    12661 ccgctatctg gaacattttt ctggtcatac tttgagtacg gttcatcctt gtcaaattca
    12721 ggactttata cctgaaaacc atgatattcc tgttcaggag gtattaattg atgaaggaaa
    12781 tctttgatag acgttaccct gtgacgagtt tcttcctctt agtgacggcc ttggtatttt
    12841 tactaatgtt ggtcactgca ggcggaaact ttgacagggc agatacatta tttcgatttg
    12901 gagccatgta tgggccagct attcgcctct ttcccgagca ggtttggcgt ctcttgtctg
    12961 ccatttttgt tcatattggg tgggaacatt tcattgttaa tatgctttca ctttattatc
    13021 ttggaaggca ggtagaggag attttcggct ctaagcagtt cttttttctc tatctcttat
    13081 caggaatgat gggcaatctc tttgtttttg tatttagtcc taaatcctta gcagcaggcg
    13141 cctctacctc tctttatggg ctatttgccg cgattatcat tcttcgctat gcaacgcgta
    13201 atccttatat ccagcagttg ggccaatcct atatgacact ttttgtggtt aacattattg
    13261 gaagtgttct gattccaggg atcagcctag caggccatat cggtggagca gttggtggcg
    13321 catttctagc agttatcttt ccagttagag gagaaaaacg gctgtataac accagccaga
    13381 gattaggagc ggtagtcttg ttcgtaggac tcgccatttt gcttttctac aagggaatgg
    13441 gaatgtgacg aagttgaaag aaaatttgtg taatgaaaaa agataaggca ttttttgaac
    13501 cttatctttt tattttattc cttctcagtc aattcttttc caagttggat gaggtaattc
    13561 ttcaaatcat ctttgacttg tggatgtttg agggcgtagt caatagatgt tttcataaag
    13621 ccaaacttat ccccaacgtc gtaacgagct cctgtaaatt tacgggcaaa aacacgctgt
    13681 gttttattaa gagtatcgat tgcatcagta agttggattt catttccagc accaggagct
    13741 tgcttttcga gaatctcaaa aatttctggt gtgagtagat agcgaccgat gattgccaaa
    13801 tcacttggag tctcctcggg agctggtttt tcaacaaagg tttcaacact gtaaagacca
    13861 tcttttcctt cgtcttgagg agcaatgact ccatatgatg aaacgtcttc gtgtggtacg
    13921 ggcatgacag caatggttga tgcgtgtgtc ttttcgtaat cattcatcag ttgttttgtc
    13981 aaaggaacgg ccttctcgtc tgtgatgtcc atcaagtcat cacccagcat aacaacgaag
    14041 ggttcatttc ctacaaaagc tttggcttgt aagacagcgt ctccaagacc acgagggtga
    14101 gtttggcgga tgaaatgaag gcgcatgcca gttgcttcat ctaccaattt taacaaatcc
    14161 gttttgcctt tttccttaag attgtattca agctcaaagt ttgaatcaaa gtggtcctca
    14221 atagaacgtt ttgatttacc agtgacaact agaatatctt caatacctga tttgagagcc
    14281 tcttccacga taaactggat agttggtttg tctacgattg gcaacatttc tttggcaaag
    14341 gccttggttg ctggtaaaaa tcgagttcct agtccagcag cagggataac tgcctttcta
    14401 acttttgatg tcataaaaat cctttctata gagggttaag accactcatt ttctgcttta
    14461 aattcattgt tcatgatgtc ataaatggca tctttgatat tggttccgtg ataaataact
    14521 tggtaaatag cctgtgtaat gggcatatag actccaagtt cttgggctag ttcataggct
    14581 gctcgagtcg ttgaaattcc ttcgattacc atgcccatat tagcttctat atcagctagg
    14641 gattctcctc gtccgagagc atctccagct ctccagttac gagagtggat ggaagttccc
    14701 gttacgatca aatctcccac accagataag ccgctatagg tcaatggact ggccccgagt
    14761 gctaccccta ggcgggtgat ttctgctaaa cctcgagcga tgatggctgc cttagcatta
    14821 tcaccaaatc caagaccatg taaagctcca gcaccgacag caataatatt tttaagagca
    14881 ccagcagttt caaccccgat aacatccgta ttggtataaa gtcggaagta gtgattacta
    14941 aatagctcct gaacgtattg agctgtttgt aaatctttag aagcagcagt tattaaagtt
    15001 aggtcacgca caatggtctc ttctgcatga ctaggccctg aaacagcgac gatatcacta
    15061 cggagatgtt caggaatttc ttcttcaaga atggttgata atcgtttatg gctatcaggt
    15121 tctaatccct ttgatgcgtg catgatgata accttatggt ccaaggtttg tgcaacttgc
    15181 tgggcaacaa gtcgtgtcac ttttgttggg acaacaaaca aaatcgcatc cacatttttc
    15241 aatgtttctg ctaagtcggt gtaggcaatg atattttcgt ctagaacgac atctttaaag
    15301 tagggcttat tagtatggtg tgtattaatt tcattgattt gctcgggaag atttccccaa
    15361 atacgtacct cgtgtccatt gtcatttaag acttgtgaaa gggcggttcc ccaagaacca
    15421 ggccccaaga cggcgacggt ttgtttttcc atgatttcct ccttgataga tttctttctc
    15481 ttattatatc atattctagg ggattttgca cttgcattac tggggtatgg tggaaaaata
    15541 cacaaagatc gagatgaagg gataaactct tagtctttag ttaaagtgag aagaaatctg
    15601 atagatagtt tgattcagta tatgctataa atagaggtaa acaactcagg aggttcttgt
    15661 aggttgcgaa agtttggcga aaaaattaaa agattacgtt tggctaaaaa aatcagtcgt
    15721 tcagaatttt gtggtgatga gtctgaatta agtatccgtc aattaattag aattgaaaat
    15781 ggagaatcca gaccaacact aacaaagtta aaatatatcg ctgaacgttt gggggttgaa
    15841 gattacaagt tgatgccaag ttatatagag ttggataagg aatacctaga attgaagtat
    15901 ttcttgatga ggactcctac atacgaagat gaaactatcg cccaaaagaa agagagtgtt
    15961 ttgataagat ttttgaagag tattatgata ggctacctga ggaagaaaga tttatcatcc
    16021 caaattattc atatctggca ctaacgaact acacagttca aaaattacca gaaaagctag
    16081 ttgaaatact gtccttctgg tgattttgct taatttctga tgttcgagac ataattgagg
    16141 agatttgtct tgattttttc ctaaaaaagg gcagactcct cccttggttt gatgctcgat
    16201 ttttaaaata aggtgactta ttctgttagg catgttttcc cctgccctct agctctatat
    16261 ggaacaggga gtatcagatt tatctggcag attgtatcaa ataaggcttg aaactgtttt
    16321 gaagaggcat atagacttga gaatttgaga atatgtcgtc tagcagtaga gacatatttt
    16381 ccggcaatat gaaggaagag acgtcgaaaa cgcttgatag tcaaggcctt tacttcatca
    16441 ccagctagct gctttaaaaa gaggtagaga ttataagcca gacagcccat catcatacgt
    16501 acttcattct taatcatggt cgaactatct gtcttatccc caaagaatcc tgctttcctt
    16561 tctttgataa agttttcagc attccctcgt tcacgataga attgaaacag ctcctcacta
    16621 tctacactgc ttaaattgtt caaatgaact tttttacaac cataaaaaag agcacttaat
    16681 cgtactcttc tcttttaagg attagttgaa ttaattcaaa tccactagtt ctcctgtttc
    16741 taggtagact aggcgttcac aaatgttagc aatgtaatca gcgaagcgtt ccagatgccc
    16801 tatgatataa aggtattgtg ttccattggg aattgaggtt tcttggtctt tcataagtcc
    16861 aatgatttcc tttgataagg cataataata ttggtcaatc tgttcatctt tttgagcaat
    16921 actaatagct tttgaggctt ggtgcaaagg aaaggcaacc aataaatcgg ctagcatgct
    16981 gagggataat ttacccattt ggtgtaactg ttcttcgtca ggggctagtt gattttcttt
    17041 tagttgcaaa acagctttgg caatgcctgc catatggtct cccatacgtt caaggtctga
    17101 acaagaagac atgatgctaa tcacaaatcg aaggtcagac acttgtggct gctgcaaggc
    17161 caacaaacgg gcacaggtca attcgatagc gctttgacct tggttgatag catgatcctt
    17221 attgataatt agctctgcca tctccttgtc tttggaggct aaggccagta aggcttttga
    17281 agctgtttca aggacaagtt gccctagtcc taaaaaggat tgttctaatt catgcaattc
    17341 taagtcaaat tgatttctca taggtttttc cttccttatc cgaaccgtcc tgaaatatag
    17401 tcttctgtgc gctgatcttt tggattggta aacacgtcaa cggtatctcc aaattcgcaa
    17461 atttctcctg ttaagaaaaa agcagtttta tctgaaatac gtgaagcttg ttgcatgtta
    17521 tgggtaacaa tgataatcgt ataatctttt tttagttgct gaatgaggtc ttcaattttt
    17581 aaagtggaga tagggtctaa ggctgaagtc ggctcatcca ttaacagaat atcaggttct
    17641 actgctaaag ctcgcgcaat gcaaaggcgt tgctgctgac cgccagataa ggacatggca
    17701 ctctttttaa gatcatcttt gacttcttcc caaatggctg ccccttttaa agatttctcc
    17761 actaaggcat ctaattgttt tttgtctcga ataccatgtg tccttgggcc ataagccacg
    17821 ttatcataga tagacatggc aaagggatta ggctgttgaa aaaccatccc tacacgctta
    17881 cgtagctgat taaggttgaa tttgctacta taaatatctt gctcatctaa gaggacttgg
    17941 ccttcaatat ggcaagaagg aaccaaatcg ttcatccggt taagggtttt tagaaaagtt
    18001 gatttgccac aaccagatgg gcctatcaag gcagtaatct gcctttctgg taattgaatc
    18061 gaaatatttt ttaaggcttg aaaatccccg taaaataagt ctaggtgtct aactgaaaat
    18121 gttcccatac taggaagctc ctttcacaag ttttcgagat aataagcttg atagagtatt
    18181 tatcattaaa acagtaataa tcaaaatcac accggtagca taggcttcat tgacatgtag
    18241 cccctcactt gacagcatat acatatgcag ggctagagaa cgacctgaag acatgagact
    18301 acttggcgta ttggtagagg tacctaatgt atacatgagg gcagctgtct caccaacgat
    18361 acggccaata gctagtatca ctccagctaa aatacctggc atggcaactg gtagaacaat
    18421 tctaaaaaca gtccgtaact tacctgcccc aagtccataa cttgcttgac gcatgctatc
    18481 actaacagat aaaagggctt cttctgttga gcgaataatg actggcaaca ccatgatgac
    18541 tgaggttaag attcctgata acagagagta ttgaaaacct aagaagacta caaagaagag
    18601 catgccaaac agaccaaaaa caatggaagg aatcccagac aaggtatctg aggccaatcg
    18661 catgatttta acacaaaggg aatctttttt tgtatattcc acaagataaa aaccagcaaa
    18721 aatccctatg ggcaaggcta aaagaagagc accaaagacc agaataacgg tggaaataat
    18781 cgctggcata agggaaatgt tctcagaagt ataagtccaa gaaaagaggg atagacttag
    18841 atgaggtaag cctttgatga ggataaaacc aatgattaaa aagagagagc caaaggttaa
    18901 agctgaaaaa caataaacga gaagttttag caggtattta ctcataagat gattttcctt
    18961 tcaagtaggc aaagtaggca ttaatcaaga gaataaggaa aaagagaact gctgaggttg
    19021 caataagggc ttccctatgc tgacctgatg cgtaagccat ttccagaaca atattggttg
    19081 ttaaggttct ggttcctgaa aagagtccac ttggaataat cggctggttg cctgccacca
    19141 agataactgc catggtttca cctactgcgc gaccgattcc taaaataact gctgataaaa
    19201 taccagatct cgcagctggc aagatgacac taaaaatact ccgttcatga ctagctccta
    19261 gagccaagct accagaataa tacgttttgg gaactgttcg gatagcagat tctgacaaac
    19321 tgataatagt tggcaaaatc attattccta atagtaacga agcggttagg acactcatgc
    19381 catttcctaa aaagcttcta atccaaggca ccaataattg taggccgaaa aaaccataaa
    19441 caatagatgg aatggctgcc atcaagttga tagctgattt taagaagcca tagacgggct
    19501 ttggacaata ataaaccata aacaccgatg tcaagatgcc tgttggcacc ccaatcacaa
    19561 tcgctcctaa ggtaattaat aaggaaccaa cgatcattgg taaaatacca tagcttgccg
    19621 gaatgttcgt tggcgaccaa tcactgccta ataaaaaacg ggcaaagccg tagttagcta
    19681 tgaaaggtaa gccattacta aaaataaaga aacagattag caaaatagct acaacagcta
    19741 ctgttgcact catgaaaaaa attgccctaa aaactgcttc tttgaaggct tgttttgtca
    19801 catcttgtcc tttctagtga agaaagtaag ggagatacga cacctcccta cttgccttct
    19861 ttatcttatt gtacgatgaa acgtctgcat ctctttagag atttatggag caaacatttt
    19921 atttaatctt gtcccaggtg gttaatttgc cactaaaaac gtctgcaagt tcagccatac
    19981 tgacttggct tgccttattg tcattattga ccacaacagc aataccgtct aaagcaatag
    20041 catcatgggt gagactctta ccttcttcag gagttaattc cctagaaacc ataccaatat
    20101 cagcggtttt ctccttaaca gcggtaatac ctgctgaaga cccattagag gtaatatcaa
    20161 tcgtaacttc tggattttct tttttataag cttctgctaa tttttccatt aaagaagata
    20221 ctgaagtgga acctacaaca gacaacttgc ctgataagtg ttggcttgta tattctgtgg
    20281 tttcagtttt agcttcaata aatttattat ctgtgaccac ttgttgacct tgtttggagt
    20341 ggataaagct gataaaatct tgacctagct tggaaagatt agaagaccaa acaatgttga
    20401 agggacgttg aagagggtat tcaccatcta aaactgtgtc tcgactagcc ttgacaccat
    20461 caatctctaa agccttgaca gatttcgtta aagatcccaa ggagatgtag ccgatagcat
    20521 tagcattccc ttgaactgct gagagaacac cttctgtact attttgaatc acagctgttt
    20581 tggcagtgtt gtcaattttt ttatcaccgt cttttttgag aatccctgtg atttctgtga
    20641 aggcaccccg tgttccagag ccattttctc gtgaaatcac ctcaatcgtt cctgaagctg
    20701 actgtttgga agcagctgac tgattgccac aggcaacaag cccaaatcct gataagccaa
    20761 tggctgcaag agtaagcatt tttttgaatt tcataataat cacctttatc tctatgtatt
    20821 tttcttgtgt aggcttacta catttatagt ctaacaagtc tttgtaaagg tttatccctg
    20881 attcatgtaa agattgtgta aagaatcaaa aaaagccact tttgaaaaat ggctgctcct
    20941 aaaaatagct ttaaaaatta ttagtcctgt gcgaaagatt ggttaggaag aaaaatcgtg
    21001 aagcaactgc ctctgccaag ctgactcgtc accgtgactt ggccacctaa taattgactg
    21061 agttctttga caatggcaag gccaagacca gtgccaccag tttgtctgct tcgaccttta
    21121 ttaactcggt aaaaacgttc aaaaatacga tcctgctcta attgactaat accaatccct
    21181 gtatctgata cagaaatctt aatgccttcg ttcacctttt gggtcttgac ctcaattttt
    21241 cccccttgtt cagtgtaacg gatggcattg gataaaagat tgagtaagat ttgggaaagt
    21301 aattgactat ctgatacgag ggtgacatca tctggcacct gcacctttag ctgtaaatcc
    21361 ttcttcttga gctgaggttg caagctttga gtcaaatcct gtacaaattc tgccaaagaa
    21421 agggtcgtcc attgtatagg catttgttga gccttagata aggtaagaag atgctcaaca
    21481 atatgctcaa gacgcaaact ttctttgtaa ataatgtcta gaaagtcatc cttgagcgct
    21541 tcttcttcag ctgacatccc cttaatggtt tcagcaaagc ccttaatcga agtaactggt
    21601 gtcctcaatt catgggaggc atttgagaca aaggctaaat ttaacttttc ataagttcta
    21661 atcgttgtta aatcatatag caagacgagc acagcttcca cagattgggt ggggctaaaa
    21721 acgggaactg ctgttacttc taaaatcaag tcaccctcat gaaacccact tacttcttgt
    21781 tttaaccttg ttttttgatc aaaggcttgg tgaactaaat ttcgaatatc catccgtttg
    21841 aggtcatcaa gtgaacttat gtcgccgtcc acatcgggaa aataatgagg cagagagcga
    21901 ctggataata acatctgacc ttgagcggaa actaaaaacg tccccatggt taggtgcgac
    21961 agaagaacct ccattgtttc ggctaggtcc ttgtattgct gatcctgttg ggagactttg
    22021 gtttttaggc cagacacata ctgagccaaa gactttaagt cttcttgccc tttttctaaa
    22081 aagtattcac tactggtcaa gagaggttgg tgcaaggtct caaaagcaac ttcccatttc
    22141 caaaggcaaa agagccagta gccaccttgt cccaaagaaa gggctagaag aaagagaccg
    22201 atgcctttac tgatccaagt taatgccatc cctgcaatca gaatgaggct aacacttaga
    22261 ttgactagcc aaaattgaag gtagcgtttc atctataact ccttgaactt ataaccataa
    22321 ccccgaatgg ttcgaataaa ttgaggggct ttaggattgt cttcaatttt ttccctcaac
    22381 ttaccaatat gaacgtccac caaacgtgtt tcctgcccaa agtcataccc ccagatacgt
    22441 tccaaaagac gctctctagt cagtgtcatg ttgggatgtt tcataagata gagcaagagt
    22501 tcaaattctt ttggggtcaa actcagtaac ttattcgcct tgtagacttc atgacgctca
    22561 gggtatactt tcaaggtccc aaatagccaa gaatcgtcag cgatattatc tgaatcatct
    22621 ccttcttgtt ctcctttagt tcgcctgagg acagccttga cacgcgccag caattctcta
    22681 gggctaaaag gcttggtcag gtagtcatca gcccctaatt ccaaggccaa aaccttatca
    22741 aattcatcac ttttcgcaga aaccatcata attggagttt tgacgccttt ggctctcagc
    22801 cgcttacaaa cttccatgcc atctaattgt ggtaacatga tatcaagcaa gataaaatca
    22861 aagggttctg tttctgccaa agctaaggcc ttccgtccat ttgttaccaa ttgagtagaa
    22921 aagccttcct tacttaaatg gtagtcaagc aatttcagaa tgtgttcttc atcatccact
    22981 aataagactt gttttgtcat ctattatctc ctattggtaa cattataaca caattatcag
    23041 aaatcctaac attgctaaat cagattaaat ttgcttatca agactagtat ctggtcaaac
    23101 gctcaatcat ctccttgtgc tctggatagg tcgccagtag atctaccctt tcaaataatt
    23161 caaaatcctc aaattcaaaa ccaggagcaa caagacaaga aaccagagca tcatccttat
    23221 caactgttga tccccaaata gtgcccttag gaacacagta gtgaagttgt tgccctttgg
    23281 atatgtccag gcctaaagtg actgcttcgt agtgaccatc tgctgtgatc atgtgaacag
    23341 taagtgggga tcctgcatga aaataccaga tttcatctgc tgtcaatcgg tgaaaatgtg
    23401 aaggattcgt ttcttcttaa taagaaataa atactggtat aaagcgccct tcccttacca
    23461 gcaaggttta tggtgtctga agcttttttt gtttgtctaa aatagccacc ttcaacatgg
    23521 ggagctaact ctagagttct tatcaagtct tctttatccg tcggagccaa tgggttgaag
    23581 taactcttgt tcaaagtggt tttacgattt caagaactcc tctcagttct gaggacacgg
    23641 taatgattga tgcgacggaa gtacaaatca atcgccctaa aaaaagaatt agcgaattat
    23701 tctggtaaaa aaaatgccac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa
    23761 ttgtttcttt ggatatcgct gtgaactatt gtcatgatat gaagttgttc aaaatgagtc
    23821 gcagaaatat cggacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga
    23881 agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagcca ctaacagttg
    23941 aagataaagc ctataaccat gcgctatcca aggagagaag caaggtcgag aacatctttg
    24001 ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg
    24061 gattacgaat gaatttgatt gctggtatta tcaatcatga actaggattc tagttttgca
    24121 ggaagtctat tatttggtta ggtgaattag tgaagcgttt aggcaagtgt ctctggttac
    24181 gacgtcatgg cctctaaatc gattatattt aggggtcatg actagtgaag cagttagcta
    24241 gttcgcatat aagcggctag cgtctaacaa ttaggaactt tagttccaat aactttaaga
    24301 ttacgacgtt ttaggacata aatcgatcat atttatgtcc taaaactagt gaagcgccta
    24361 gccaaagtcc gaataggatt tggcgttagt tacttagatt gctttgcaat caagtaactt
    24421 tggcgattta catcttctct ggcgcttcta ctccaagcaa gcgaagggct tctttgagaa
    24481 cgactgcggt tgcgtagctg agggctagac ggctgtcgcg ttctgggctt tcatccaaga
    24541 tacgtgtatg tgcatagtat ttgttaaagg attgagccag gctaattgca aatttagcaa
    24601 tgatagaagg ttcaaagtta tctgccgcac ggttgataat acgtgggaag tcttgaatga
    24661 gtttaatgat ttcccagctt tcagtatcat tcaagctata gttgccagct gtttctggtt
    24721 tgaaatcggc tttgcgtaag atagattgga tacgagcgta ggcatattga acgtaaggtc
    24781 cagtttcacc ctcgaaggat accatagctt ctaggtcgaa gtcgtatcca tttgtacggt
    24841 cagttttgag gtcatagaat ttaatggctc caaccccaac agcatgtgct acttggtctt
    24901 tgttttctag ttcaggattt ttagcctcga tttggacctt ggcacggcta acagcctctg
    24961 caacagtagg ctctagcaag atgacattcc ctttacgagt agagagcttc ttcccttctt
    25021 ttgtaaccag accaaaagga acgtgggtaa tgtcgtcact ccaatcgtag cccatctctt
    25081 gcaagacagc tttgagttgt ttaaagtggg cagattgctc ttgaccaacg acgtagatag
    25141 atttagcaaa ttggtattca tttttacggt agagggctgc agccaagtca cgtgtgatat
    25201 agagagttgc accatcagac ttcttgatga gggctggatg ttcaattcca tatttctcaa
    25261 gattcacaac ttgggcacct tctgattcaa gaagtagtcc tttttcagaa agaatgtcta
    25321 caactgcatc catcttatca ttgtagaagg cttctccgtt atagctgtca aattcaacct
    25381 tcaattcatt gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac cattgccaaa
    25441 gagcgagagc ttcctcatct ccattttcaa gtttacggaa ccattcgcgc gcttcttcat
    25501 ccaagctagg gtcattttca gcttcagcgt tgatgcggac atagagttta aggagttcat
    25561 cgattggatg agcttttaca gcttcttcgt cgccccattt tttgtaggca acaatcaaca
    25621 tcccaaattg tttaccccag tctcccaaat ggttgacctt gaccgtttga taaccgattt
    25681 tttggaaaat atgtgacaag ctatctccga taacagttga acgcaggtgg ccaatagaaa
    25741 atggtttagc gatattcgga ctagacatgt cgataacaac attttcttgt ttgccaatat
    25801 tttggtcagc atagtgttct ttttcagtgg taacagcttg caatacttga gcagaaatgg
    25861 cagatttatc aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt tcaaaggctt
    25921 ggctgttcat tttttcagcc agttcagccg caatcatttg tggtgcttta cgttcgactt
    25981 ttgcaagaga aaaagcaggg aaagcaatgt ctcccatttc tgagttttta ggggtttcca
    26041 gtaactttaa aatagcctct tggtccaggc tatcaatgat gctagataat tcgctagcaa
    26101 tcaattcttt tgtattcatt aagagctcct ttttggactt ttctactatt ttatcacaat
    26161 tttaaagaaa gaagaaaaaa tttttgaaat ctcctgtttt tttggtataa tatggttata
    26221 aatatagtta taaatatgca cgcaagagga ttttatgaga aaaagagatc gtcatcagtt
    26281 aataaaaaaa atgattactg aggagaaatt aagtacacaa aaagaaattc aagatcggtt
    26341 ggaggcgcac aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc gcgaaatcgg
    26401 cttgaccaag gtcaagaaaa atgatatggt gtattatgta ctagtaaatg agacagaaaa
    26461 gattgatttg gtggaatttt tgtctcatca tttagaaggt gttgcaagag cagagtttac
    26521 cttggtgctt cataccaaat tgggagaagc ctctgttttg gcaaatattg tagatgtaaa
    26581 caaggatgaa tggattttag gaacagttgc tggtgccaat accttattgg ttatttgtcg
    26641 agatcagcac gttgccaaac tcatggaaga tcgtttgcta gatttgatga aagataagta
    26701 aggtcttggg agttgctctc aagacttatt tttgaaaagg agagacagaa aatggcgata
    26761 gaaaagctat cacccggcat gcaacagtat gtggatatta aaaagcaata tccagatgct
    26821 tttttgctct ttcggatggg tgatttttat gaattatttt atgaggatgc ggtcaatgct
    26881 gcgcagattc tggaaatttc cttaacgagt cgcaacaaga atgccgacaa tccgatccct
    26941 atggcgggtg ttccctatca ttctgcccaa cagtatatcg atgtcttgat tgagcagggt
    27001 tataaggtgg ctatcgcaga gcagatggaa gatcctaaac aagcagttgg ggttgttaaa
    27061 cgagaggttg ttcaggtcat tacgccaggg acagtggtcg atagcagtaa gccggacagt
    27121 cagaataatt ttttggtttc catagaccgc gaaggcaatc aatttggcct agcttatatg
    27181 gatttggtga cgggtgactt ttatgtgaca ggtcttttgg atttcacgct ggtttgtggg
    27241 gaaatccgta acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc tgaggaagaa
    27301 gaacaaatcc tcagccgcca gatgaatctg gtactctctt atgaaaaaga aagctttgaa
    27361 gaccttcatt tattggattt gcgattggca acggtggagc aaacggcatc tagtaagctg
    27421 ctccagtatg ttcatcggac tcagatgagg gaattgaacc acctcaaacc tgttatccgc
    27481 tacgaaatta aggatttctt gcagatggat tatgcgacca aggctagtct ggatttggtt
    27541 gagaatgctc gctcaggtaa gaaacaaggc agtcttttct ggcttttgga tgaaaccaaa
    27601 acggctatgg ggatgcgtct cttgcgttct tggattcatc gccccttgat tgataaggaa
    27661 cgaatcgtcc aacgtcaaga agtagtgcag gtctttctcg accatttctt tgagcgtagt
    27721 gacttgacag acagtctcaa gggtgtttat gacattgagc gcttggctag tcgtgtttct
    27781 tttggcaaaa ccaatccaaa ggatctcttg cagttggcga ctaccttgtc tagtgtgcca
    27841 cggattcgtg cgattttaga agggatggag caacctactc tagcctatct catcgcacaa
    27901 ctggatgcaa tccctgagtt ggagagtttg attagcgcag cgattgctcc tgaagctcct
    27961 catgtgatta cagatggggg aattatccga actggatttg atgagacttt agacaagtat
    28021 cgttgcgttc tcagagaagg gactagctgg attgctgaga ttgaggctaa ggagcgagaa
    28081 aactctggta tcagcacgct caagattgac tacaataaaa aggatggcta ctattttcat
    28141 gtgaccaatt cgcaactagg aaatgtgcca gcccactttt tccgcaaggc gacgctgaaa
    28201 aactcagaac gctttggaac cgaagaatta gcccgtatcg agggagatat gcttgaggcg
    28261 cgtgagaagt cagccaacct cgaatacgaa atatttatgc gcattcgtga agaggtcggc
    28321 aagtacatcc agcgtttaca agctctagcc caaggaattg cgacggttga tgtcttacag
    28381 agtctggcgg ttgtggctga aacccagcat ttgattcgac ctgagtttgg tgacgattca
    28441 caaattgata tccggaaagg gcgccatgct gtcgttgaaa aggttatggg ggctcagacc
    28501 tatattccaa atacgattca gatggcagaa gataccagta ttcaactggt tacagggcca
    28561 aacatgagtg ggaagtctac ctatatgcgt cagttagcca tgacggcggt tatggcccag
    28621 ctgggttcct atgttcctgc tgaaagcgcc catttaccga tttttgatgc gatttttacc
    28681 cgtatcggag cagcagatga cttggtttcg ggtcagtcaa cctttatggt ggagatgatg
    28741 gaggccaata atgccatttc gcatgcgacc aagaactctc tcattctctt tgatgaattg
    28801 ggacgtggaa ctgcaactta tgacggaatg gctcttgctc agtccatcat cgaatatatc
    28861 catgagcaca tcggagctaa gaccctcttt gcgacccact accatgagtt gactagtctg
    28921 gagtctagtt tacaacactt ggtcaatgtc cacgtggcaa ctttggagca ggatgggcag
    28981 gtcaccttcc ttcacaagat tgaaccggga ccagctgata aatcctacgg tatccatgtt
    29041 gccaagattg ctggcttgcc agcagacctt ttagcaaggg cggataagat tttgactcag
    29101 ctagagaatc aaggaacaga gagtcctcct cccatgagac aaactagtgc tgtcactgaa
    29161 cagatttcac tctttgatag ggcagaagag catcctatcc tagcagaatt agctaaactg
    29221 gatgtgtata atatgacacc tatgcaggtt atgaatgtct tagtagagtt aaaacagaaa
    29281 ctataaaacc aagactcact agttaatcta gctgtatcaa ggagacttct ttgacaattc
    29341 tccacttttt tgctagaata acatcacaca aacagaatga aaaggagctg acgcattgtc
    29401 gctccctttt gtctattttt taaggagaaa gtatgctgat tcagaaaata aaaacctaca
    29461 agtggcaggc cttggcttcg ctcctgatga caggcttgat ggttgctagt tcacttctgc
    29521 aaccgcgtta tctgcaggaa gtattagacg ccctccttac tgggaaatat gaagctattt
    29581 atagtatcgg ggcttggttg attggtgtgg ccgtagtcgg tctagttgct ggtggactca
    29641 atgttgtcct cgcagcctat attgcccaag gagtttcatc cgaccttcgg gaggatgcct
    29701 tccgtaaaat tcaaaccttt tcttatgctg atattgaaca atttaatgcg ggaaatctag
    29761 tcgttcgaat gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg accttccaaa
    29821 ttcttttcag acttcccctc ttgttcatcg gttcgtttat cctagcggtt caaaccttac
    29881 cttctctgtg gtgggtgatt gttctcatgg tagtcttgat ttttggtttg actgctgtca
    29941 tgatgggaat gatggggcct cgttttgcta aatttcaaac ccttcttgag cgcatcaatg
    30001 ccattgccaa ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc caagaaaaag
    30061 agcaatttgc taagtttaca gaggtctcaa acgagcttct tggtcaaaac ctttacattg
    30121 gttatgcctt ttcagtagtg gaacccttta tgatgttggt tggttacggg gcggtcttcc
    30181 tctctatttg gctggtcgcg ggaatgattc agtcggatcc gtctgttgtt ggttccatcg
    30241 cttcttttgt taattaccta agccagatta tctttaccat tgttatggtt ggatttttgg
    30301 gaaattctgt cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt cttgacgcag
    30361 agccagctat gaccttcaag gatatcccag atgaagagtt ggttggaagt cttagctttg
    30421 aaaatgtgac ctttacctat ccaatggaca aggaaccgat gctgaaaaat gtgagcttta
    30481 ctattgaacc tggtcaaatg gttggtgtag ttggagcgac tggtgcagga aagtcaacct
    30541 tggctcaatt gattccacgt ctctttgatc cacaggacgg ggccattaaa attggtggca
    30601 aggatattcg agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc gttctccaac
    30661 gtgccattct ttttagtgga acgattgcag ataacttgag acaggggaag ggaaatgcta
    30721 ccctatttga aatggagcgc gcagccaata ttgcccaggc tagtgaattc attcatcgta
    30781 tggagaaaac ctttgaaagt ccagttgaag aacggggaac caatttctct ggtggacaaa
    30841 aacaaaggat gtcgattgcg cgtgggattg tcagcaatcc acgtattctg atttttgacg
    30901 attcgacctc agccttggat gccaaatcag agcgcttggt gcaagaagct ttgaataagg
    30961 acttgaaggg gacgacaacc attattattg ctcaaaaaat tagctcggtt gtccatgcag
    31021 acaagatctt ggttctaaat caaggacgat tgattggtca aggtacgcat gcagacttgg
    31081 ttgccaacaa tgccgtttac cgtgaaatct atgaaacaca gaaatgaaag acaaactata
    31141 agaaaagtca atagttttat ctaaactatt tcttatttca atttgatgat ttggcgatga
    31201 ttttagagca cggcaaaaag cccttgaaaa agtccatttt ttcaaaggta atcctgtgtt
    31261 gatttcagaa attacatcac tttttgttcg tcaaatggca gctctttttt aggatataaa
    31321 acagggttcg gataagtttt tttgcaaggt ggatgatggc tacattgtaa tgttttcctt
    31381 gttctaactt agtcttaaaa gcaggtgaaa agtgagggca tgctttggca gcttgtatga
    31441 gtacctaccg cagatgaggg gaaccccgtt tgaccattct ttctgctaaa tcaatctgac
    31501 ctgactgata aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa
    31561 aggcatgaat atttcgaatc tcggctaaaa tgaccgcccc taaacgattc tcaatcccag
    31621 taaccgtcgt gatgaccgag ttgaactcag ccatcaagtc attgacacat ttttccgcct
    31681 tgtcaatgag cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtctatgcg
    31741 ttatcaaact cattaccaat taaaacaaat gtggttagat cctttcggaa attgtcaagc
    31801 gattggagga aatgaactaa tccacagcgg cttattccaa gtataccact tgggctttgg
    31861 cagtagctaa ctgcgctaaa tataatataa ggaggagtaa aatgaagaca gttcaatttt
    31921 tttggcatta ttttaaggtc tacaagttct catttgtagt tgtcatcctg atgattgttc
    31981 tggcgacttt tgcccaagcc ctctttccag tcttttctgg acaagcggtg acgcagctag
    32041 ccaatttagt tcaagcttat caaaatggca atccagaact tgtatggcaa agcctatcag
    32101 gaatcatggt caatcttggc ctgctggttt tggttctatt tatctctagt gtaatataca
    32161 tgtgtctcat gacgcgcgtg attgcagaat cgaccaacga gatgcgcaaa ggtctctttg
    32221 gtaagcttgc tcagttgacg gtttctttct ttgaccgtcg acaagatggc gatatcctgt
    32281 ctcattttac cagtgatttg gataatatcc tccaagcctt taacgaaagc ttgattcagg
    32341 tcatgagcaa tattgtttta tacattggtc tgattcttgt catgttttcg agaaatgtga
    32401 cgctggctct catcactatt gccagcaccc cattggcttt ccttatgctg attttcatcg
    32461 tgaaaatggc acgtaaatac accaacctcc agcagaaaga ggtagggaag ctcaacgcct
    32521 atatggatga gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt caagaggata
    32581 tgatggcagg atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt aaaggaagaa
    32641 tgttctcagg aattcttttc cctgtcatga atgggatgag cctgattaat acagccatcg
    32701 tcatctttgc tggttcggct gtacttttga atgataagtc tattgaaaca agtacagccc
    32761 taggtttgat tgttatgttt gcacaatttt cacagcagta ctaccagcct attatccaag
    32821 ttgcagcgag ttggggaagc cttcagttgg cctttactgg agctgaacga attcaggaaa
    32881 tgtttgatgc agaggaggaa atccgacctg aaaaggctcc aaccttcact aagttgcaag
    32941 aaagtgttga aatcagtcat atcgattttt catacttgcc tgataaacct attttgaaag
    33001 atgtcagcat ttctgcccct aaaggccaga tgacagcagt tgttgggccg acaggttcag
    33061 gaaaaacgac tattatgaac ctcatcaatc gcttttatga tgttgatgct ggtggtattt
    33121 attttgatgg taaagacatt cgtggctatg acttagatag tcttagaagc aaggtgggaa
    33181 ttgtattgca agattcggtc ttgtttagcg gaacgattcg agacaatatc cgatttggtg
    33241 tgccagatgc tagtcaggaa atggttgagg tagcagcaaa agcaacccac attcacgact
    33301 atatcgaaag tttgcctgat aagtacgata ctcttattga tgatgaccag agcatctttt
    33361 caacagggca gaagcaattg atttcaatcg ctcgaaccct gatgacagat ccagaagttc
    33421 tcattctcga tgaagcaact tcaaacgtag atacggtgac agaaagcaag attcagcatg
    33481 ccatggaggt ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc ttgaaaacca
    33541 ttctcaatgc agatcagatt attgtcctta aagatggaga agtcattgaa cgtggtaacc
    33601 accatgaact tttgaagcta ggtggttttt attcagaact ctatcacaat caatttgttt
    33661 tcgaataaga aagaagttgt cctatgtggg cagctttttc ttgtccataa aaaatgttta
    33721 tcacagcctt aaaaaaaaca tattagacga aagtcatttt gagtgatatg ataggactat
    33781 cgttagcatt cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt gctgcaaatc
    33841 tatgtcccgt agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt agattcgcag
    33901 agatcattcg tcaagtcggt ggtctccctt tagtcattcc tgttggtgat gagtcagttg
    33961 tacgtgatta tgtggaaatg attgacaaac tcattttgac aggaggccaa aatgttcatc
    34021 ctcagtttta tggagagaaa aagaccgtcg agagcgatga ttacaatctg gtccgtgacg
    34081 aatttgaatt ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt atggcaatct
    34141 gtcgcggtgt ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa gaaatcgaag
    34201 gtcactggca aggactacct ttcgggacat ctcactctat tgagacagta gaaggaagtg
    34261 tggtggctaa gctatttggg aaagaaagtc aggtcaactc agtccatcgt caaagcatta
    34321 aacatttggc acctaatttc cgtgtaactg ctattgattc aagagaccaa actattgaag
    34381 cgattgagtc tatcgacgag caccgcatta tcggtttaca gtggcatcca gagtttctgg
    34441 ttaatgaaga agatggcaat ttagaattat ttgagtattt attgaatgaa ctgtaacgat
    34501 tggaacatct ggtcgttctt ttttttattt tttcaaaatt tttagaatgt ggtattttac
    34561 gcaaacgttt gaattctgat aaaaattgga gaaattcgac aaaaaaactt gaaaaaaacg
    34621 aaggtaagcg ttatgataga aaagaagaaa tattggagga agaacatgtc acatattaaa
    34681 tttgattatt caaaagtttt agacaaattt gttgcaccac atgaagtgga atacatgcaa
    34741 tcacaagtaa cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg tagcgacttc
    34801 ttgggatggt tggaccttcc tgaaaaatac gatcgcgaag aatttgaccg catcttgaaa
    34861 gctgctgaga aaatcaagtc agacagcgat gttttggttg tgatcggtat tggtggatct
    34921 taccttggtg caaaagcagc aatcgacttc ttgaatcacc attttgctaa cttgcaaaca
    34981 aaagaagaac gcaaagctcc acaaatcctt tacgcaggaa actcaatctc atctacttac
    35041 cttgctgact tggtagagta tgttgcagac aaggacttct cagtaaacgt aatttctaaa
    35101 tcaggtacaa caactgaacc agcgattgct ttccgtgtct ttaaagaact cttggttaag
    35161 aaatacggtc aagaagaagc taacaagcgt atctatgcaa caactgaccg ccaaaagggt
    35221 gctgttaagg ttgaagcaga cgctaacggt tggggaacat ttgttgttcc agatgatatc
    35281 ggtggacgct tctcagtatt gacagccgtt ggtttgcttc caatcgcagc atcaggagct
    35341 gacatcaaag ctcttatgga aggtgcgaat gcagctcgca aagactacac ttcagacaaa
    35401 atctctgaaa acgaagctta ccaatacgca gccgttcgta acatccttta tcgtaaaggc
    35461 tatgcaactg agatcttggt aaactatgag ccatcacttc aatacttctc agaatggtgg
    35521 aaacaattgg ctggtgaatc agaaggaaaa gaccaaaaag gtatctaccc aacttcagcc
    35581 aacttctcaa ctgacttgca ctcacttggt caatttatcc aagaaggaac tcgtatcatg
    35641 tttgaaacag ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc tactttggaa
    35701 gaagaccttg acggacttgg ttaccttcaa ggaaaagacg ttgactttgt aaacaaaaaa
    35761 gcaactgacg gtgttcttct tgcccacaca gatggtgatg taccaaacat gtatgtgact
    35821 cttccagagc aagacgcttt cactcttggt tacactatat acttcttcga attggcaatt
    35881 gccctttcag gttacttgaa tgctatcaac ccatttgacc aaccaggtgt tgaagcttat
    35941 aaacgtaaca tgtttgccct tcttggaaaa ccaggatttg aagaattgag caaagaactt
    36001 aacgcacgtc tataatagaa gaaaagagtg gtttgcccac tctttttact ctctttatcc
    36061 atagaaattg gactcagcca agacttgtga tataatatag aaagcaaaaa ggcagacgcc
    36121 tagataatag gagaaactat gtcaaaagat atccgcgtac gttacgcacc aagtccaaca
    36181 ggactactac acatcggaaa tgctcgtaca gcattgttta attacttgta tgcgcgccat
    36241 catggtggaa catttctcat ccgtatcgaa gatactgacc gtaaacgcca tgtcgaggat
    36301 ggtgaacgtt cacaacttga aaaccttcgc tggttaggca tggattggga tgaaagtcca
    36361 gaatcacatg agaattatcg ccagtctgag cgtttggact tgtatcaaaa atacatcgac
    36421 caactattag ctgaaggaaa agcctacaaa tcttacgtta cagaagaaga gttggcagct
    36481 gaacgtgaac gtcaagaagt agctggcgaa acaccacgct acatcaatga ataccttggt
    36541 atgagtgaag aagaaaaagc agcttacatc gcagaacgtg aagcagcagg gaccatccca
    36601 actgttcgtt tggctgtcaa tgagtcaggt atctacaagt ggcatgatat ggtcaaaggc
    36661 gatatcgaat ttgaaggtgg caatatcggt ggtgactggg ttatccaaaa gaaagacggt
    36721 tacccaactt acaactttgc cgttgttatc gatgaccacg atatgcaaat ctctcatgtt
    36781 atccgtggag atgaccatat tgctaataca ccaaaacagc ttatggtcta tgaagctctt
    36841 ggttgggaag ctccagagtt cggtcacatg accttgatta tcaactctga gactggtaag
    36901 aagttatcta aacgtgatac taatacactt caatttatcg aagattaccg aaagaaaggt
    36961 taccttccag aagcagtctt taattttatt gctcttcttg gttggaaccc aggtggtgaa
    37021 gatgagattt tctctcgtga agaactcatt aaactttttg atgaaaaccg cctcagcaag
    37081 tcaccagcag cctttgatca gaaaaaacta gactggatga gcaatgatta tatcaagaat
    37141 gcagaccttg aaaccatctt tgaaatggca aaaccattct tagaggaagc aggccgtttg
    37201 actgacaagg ctgaaaaatt agttgagctc tataaaccac aaatgaaatc agtagatgag
    37261 attatcccat tgacagatct tttcttctca gatttcccag aattgacaga agcagagcgc
    37321 gaagtcatga cgggtgaaac agttccaaca gttcttgaag cattcaaagc aaaacttgaa
    37381 gcgatgacag atgataaatt tgtgacagaa aatatcttcc cacaaattaa agcagttcaa
    37441 aaagaaacag gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc agtttcaggc
    37501 gaaatgcatg ggccagaatt accagataca attttcttgc ttggacgtga aaaatcaatt
    37561 cagcatatcg aaaacatgct aaaagaaatc tctaaataaa gaggatacaa taatggacat
    37621 ctgggaaaag atgtacgaag aagcacagaa actatacaat ccacatgaag tatcagactt
    37681 tgtttatgcc aatcatgttg tagctgcagt agaagcagaa gatggacaaa tatttacagg
    37741 attctgtatg gagggaacct gtggtgtttt ccatctctgc gcagaacggg cggccctctt
    37801 caatatgtac caattttcag gacaaactaa ggttaagaaa gtattagcct ttcgagataa
    37861 accaccttat ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat tccttttaga
    37921 gcttaatgct gaaaataaag atgcagaatt catgatggac tataatataa gaaaaacagt
    37981 taaagtcgca gaactaatcc cttattggtg gggagaagaa cgtgcttcta agtttaatga
    38041 gcaatagaag agtcagtata attctggctc tttttactat aagtt
//
LOCUS       DAVMCN010000014        35066 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVMCN010000014 DAVMCN010000000
VERSION     DAVMCN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35066
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.014"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(73..882)
                     /locus_tag="VYP85_000873"
     CDS             complement(73..882)
                     /locus_tag="VYP85_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1881411.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(884..1687)
                     /locus_tag="VYP85_000874"
     CDS             complement(884..1687)
                     /locus_tag="VYP85_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1881412.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLTFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VYP85_000875"
     CDS             complement(1697..3184)
                     /gene="tacF"
                     /locus_tag="VYP85_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1881413.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3520..4227
                     /locus_tag="VYP85_000876"
     CDS             3520..4227
                     /locus_tag="VYP85_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1881414.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4232..5254
                     /locus_tag="VYP85_000877"
     CDS             4232..5254
                     /locus_tag="VYP85_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1881415.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5271..6140
                     /gene="licA"
                     /locus_tag="VYP85_000878"
     CDS             5271..6140
                     /gene="licA"
                     /locus_tag="VYP85_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1881416.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6130..7008
                     /locus_tag="VYP85_000879"
     CDS             6130..7008
                     /locus_tag="VYP85_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1881417.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7020..7709
                     /locus_tag="VYP85_000880"
     CDS             7020..7709
                     /locus_tag="VYP85_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1881418.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7795..8643
                     /gene="dprA"
                     /locus_tag="VYP85_000881"
     CDS             7795..8643
                     /gene="dprA"
                     /locus_tag="VYP85_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1881419.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9527..10570
                     /locus_tag="VYP85_000882"
     CDS             9527..10570
                     /locus_tag="VYP85_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1881420.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            10737..12824
                     /gene="topA"
                     /locus_tag="VYP85_000883"
     CDS             10737..12824
                     /gene="topA"
                     /locus_tag="VYP85_000883"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1881421.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNKAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13045..13404
                     /locus_tag="VYP85_000884"
     CDS             13045..13404
                     /locus_tag="VYP85_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1881422.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13497..14129
                     /locus_tag="VYP85_000885"
     CDS             13497..14129
                     /locus_tag="VYP85_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1881423.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AAELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14173..14829
                     /locus_tag="VYP85_000886"
     CDS             14173..14829
                     /locus_tag="VYP85_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1881424.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14848..15942
                     /locus_tag="VYP85_000887"
     CDS             14848..15942
                     /locus_tag="VYP85_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1881425.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15954..16991
                     /gene="leuB"
                     /locus_tag="VYP85_000888"
                     /pseudo
     CDS             15954..16991
                     /gene="leuB"
                     /locus_tag="VYP85_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            16988..17257
                     /locus_tag="VYP85_000889"
     CDS             16988..17257
                     /locus_tag="VYP85_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1881426.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            17261..17620
                     /gene="leuD"
                     /locus_tag="VYP85_000890"
     CDS             17261..17620
                     /gene="leuD"
                     /locus_tag="VYP85_000890"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1881427.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17839..17982
                     /locus_tag="VYP85_000891"
     CDS             17839..17982
                     /locus_tag="VYP85_000891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881428.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            18243..18404
                     /locus_tag="VYP85_000892"
     CDS             18243..18404
                     /locus_tag="VYP85_000892"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881429.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            18568..20499
                     /locus_tag="VYP85_000893"
     CDS             18568..20499
                     /locus_tag="VYP85_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1881430.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYISPEEVETDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            20486..21802
                     /locus_tag="VYP85_000894"
     CDS             20486..21802
                     /locus_tag="VYP85_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1881431.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            21977..22963
                     /locus_tag="VYP85_000895"
     CDS             21977..22963
                     /locus_tag="VYP85_000895"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1881432.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHAESVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            23027..23098
                     /locus_tag="VYP85_000896"
     tRNA            23027..23098
                     /locus_tag="VYP85_000896"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23060..23062,aa:Arg,seq:ccg)
     gene            23281..23979
                     /locus_tag="VYP85_000897"
     CDS             23281..23979
                     /locus_tag="VYP85_000897"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1881433.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            23970..27509
                     /gene="smc"
                     /locus_tag="VYP85_000898"
     CDS             23970..27509
                     /gene="smc"
                     /locus_tag="VYP85_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1881434.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKKKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            27506..28300
                     /locus_tag="VYP85_000899"
     CDS             27506..28300
                     /locus_tag="VYP85_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1881435.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            28300..29118
                     /locus_tag="VYP85_000900"
     CDS             28300..29118
                     /locus_tag="VYP85_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1881436.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            29122..30399
                     /gene="ftsY"
                     /locus_tag="VYP85_000901"
     CDS             29122..30399
                     /gene="ftsY"
                     /locus_tag="VYP85_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1881437.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEIS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(30445..31932)
                     /locus_tag="VYP85_000902"
     CDS             complement(30445..31932)
                     /locus_tag="VYP85_000902"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1881438.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGTSPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLKKFGAKWTWQPDITYRQDGRLE"
     gene            complement(32081..32821)
                     /locus_tag="VYP85_000903"
     CDS             complement(32081..32821)
                     /locus_tag="VYP85_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1881439.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(32821..34986)
                     /locus_tag="VYP85_000904"
     CDS             complement(32821..34986)
                     /locus_tag="VYP85_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1881440.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT        10976 a         6093 c         7584 g        10413 t
ORIGIN      
        1 tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag tagtctgtat
       61 aatccccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc actcttgcat
      121 ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt ggtcatattt
      181 tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt taaaggtatc
      241 aactgggaag atttctttca tcccttcctt accgatccca actcctcctt catattgagg
      301 agtgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt agcgaggatt
      361 gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt tgctatcacc
      421 gtgaactgct cgtgattttt tgatataagc tagttgacga agagccacat acttatagct
      481 cttgtcgaca atgctcaagt ctgtaaatcg atcaattggg aagacatcga tgaaaaggct
      541 ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtgt ccaaaatcga
      601 tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt agcgagggtg
      661 attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa gggaaatatc
      721 aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca tggttccata
      781 actgagaaaa taaggaatat catgtttctt acaagtctca tcaatatagt ccagcagggc
      841 tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc tccaatttat
      901 aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc atataatctc
      961 cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt aaattctcaa
     1021 aggttaaatc gattgtttta tcaaaggtac cacttgggaa gacttccttt tccttaaatt
     1081 ttgaaggaat aaaagccata tactgcccat tttcacgact atatttttga atttctttct
     1141 cgattttatt tgcaaaataa cgaggagaaa ccggtcgaag gagcaaccaa aaggctgttc
     1201 gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta ctgaaagaca
     1261 gcagtttgaa gctttccagt ttataacaag tatcaatgac cttaggatca tcaaagcgat
     1321 ctatagggaa aatatcgata aagataccag actcataggt ttttgtattt cgagtatcaa
     1381 taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc ttatcagttt
     1441 ctaaggatag gagcttatac ttgctttttt ccttttgaaa aatgttaata aatcgttggt
     1501 agtcttctct aggcatggac agatcaatat cgtcgtccca agggataaag ccctcatgtc
     1561 gaaccgcccc aatcagagta ccgtagttaa taatatagtt gatattgtgc tttttacaga
     1621 gagtatcaat ataatccaaa atttctaatt caatttgttt ggcatcttca atggttagtt
     1681 gtttcatttt aaactcctat gattttttga atttattttt taaggctagg acatggttta
     1741 aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa gagatagctg
     1801 ataacaagac aatcaaacca gtattaatca aaaatggcaa attaatgacc atatccacag
     1861 gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag agagagtatc
     1921 gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg atgaaaatga
     1981 tatagaaaac aagtagagaa gtctctgata acatagttgt cagtaagtag tattcgggag
     2041 ccacgatatg gttgaaaaag aggagactat tcaagcccaa attgagtagc ccagcaaaga
     2101 ctgtatagac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg gaaccaagaa
     2161 tggtatctaa ggccaggata atcgtacgaa aagcgaagag agaggtcaag atgccgcctc
     2221 cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc atgagtccaa
     2281 aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc agagaaacat
     2341 aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc actccaattg
     2401 cacctgttac aaccccagct ataacggtca caattcgctg agctatggta tagtaactaa
     2461 cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg aagagcatat
     2521 tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta aaatcactta
     2581 ggtgaatctt aacaagtttg atgtctcttt taatccaaaa ataactaatc aggtagttaa
     2641 tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca tttttaacaa
     2701 ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa aagagaaaac
     2761 tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca atgagttgaa
     2821 tccccataac aaggtagacc tttttgacga ttggattatc agtaaagaag agaggatagg
     2881 ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa aaaagactag
     2941 aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc cttaaaccgt
     3001 agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg tcgactgagt
     3061 tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca gttaggatgg
     3121 gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat tttatacttt
     3181 tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga aatgaagggc
     3241 agtaagtcaa gtaatcactt tgaagtttca aatcttaagt tttaagtttt ctttaaggaa
     3301 agtatattat tctgaaggac tctaaaattt cgcagccatt tattagtaat tgctacagaa
     3361 ttcctagtca ttactagaaa tggactagtt tctttgaata atagaactgc ataattctcc
     3421 tattctagaa ggggaggacc agtatttctt ttatgatagg actagattgt ggtataatag
     3481 agagaataag tttttttagt aagacaaagg agaaaataga tgatttatgc aggaattctt
     3541 gccggtggaa ctggcacacg catggggatc agtaacttgc caaaacaatt tttagagcta
     3601 ggtgatcgac ctattttgat tcatacaatt gaaaaatttg tcttggagcc aagtattgaa
     3661 aaaattgtag ttggtgttca tggagactgg gtttctcatg cagaagatct tgtagataaa
     3721 tatcttcctc tttataagga acgtatcatc attacaaagg gtggtgctga ccgcaataca
     3781 agtattaaga aaatcattga agccattgat gcttatcgtc cgcttactcc agaggatatc
     3841 gttgttaccc acgattctgt tcgtccattt attacacttc gcatgattca ggacaatatc
     3901 caacttgccc aaaatcatga cgcagtggac acagtggtag aagcggttga tactatcgtt
     3961 gaaagtacca atggtcaatt tattacagat attccaaatc gtgctcacct ttatcaagga
     4021 caaacacctc aaacattccg ttgcaaggac ttcatggacc tttatggatc tctttctgat
     4081 gaagagaagg aaatcttgac agatgcatgt aaaatctttg tgatcaaagg aaaagatgtg
     4141 gccttggcca aaggtgaata ctcaaatctg aagattacaa ccgtaacaga tttgaagatt
     4201 gcaaaaagta tgattgagaa agactagtaa aatgattaat caaatttatc aactaactaa
     4261 gcctaagttt atcaatgtca aatatcagga agaggctatt gaccaagaga atcatatcct
     4321 tatccgtccc aactacatgg ctgtctgtca tgcggatcag cgttactatc agggaaaacg
     4381 tgatcccaag attttgaata aaaagcttcc aatggcaatg attcacgagt catgtggaac
     4441 cgtcatttct gacccgaccg gaacctacga ggttggtcaa aaagttgtca tgattcccaa
     4501 tcagtctcct atgcagagtg atgaagaatt ctatgaaaac tacatgacag ggacccattt
     4561 cttgtctagt ggatttgatg gctttatgag agagtttgtt tctctcccta aagatcgtgt
     4621 ggtggcttat gatgctattg aagatacggt tgcagccatt acagagtttg tcagtgtggg
     4681 catgcacgct atgaatcgtc tattgactct tgctcatagc aagcgggagc ggatcgccgt
     4741 tattggagat ggaagtttag cttttgtggt tgccaatatt atcaactata ctttgccaga
     4801 agcagagatt gtggttattg gtcgtcattg ggaaaagttg gaactcttct catttgccaa
     4861 agaatgctat attacggata atattcctga agatttggcc tttgaccatg cttttgaatg
     4921 ttgtggtggt gatggtactg gaccagctat taatgacttg attcgctaca ttcgtcctca
     4981 gggaacgatt ctcatgatgg gagttagcga atataaagtc aatctcaata ctcgcgatgc
     5041 cttagaaaag ggcttgattt tggttgggtc atctcgttct ggtcgcattg attttgaaaa
     5101 tgctatccaa atgatggaag tcaagaaatt tgccaatcgt cttaaaaata tcctttatct
     5161 agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc tttgcaaccg atttaaacac
     5221 agcctttaaa acagtgttta agtgggaagt ataagtactg gaggttaatt gtggagaaaa
     5281 tcattaaaga aaaaatttct tccttactta gtcaagaaga ggaagtcctc agtgttgaac
     5341 aactgggtgg aatgaccaat caaaactatt tggccaaaac aacaaataag caatacattg
     5401 ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg acaagatgaa aagtacaatc
     5461 ttgaactact aaaggattta ggcttagatg taaaaaatta tctttttgat attgaagctg
     5521 gtatcaaagt aaatgagtat atcgaatctg cgattacgct tgattcaacg tcaatcaaga
     5581 ccaagttcga caaaattact ccaatattac aaactattca tacgtctgct aaggaattaa
     5641 gaggagaatt tgctcctttt gaagaaatca aaaaatacga atccttgatt gaagaacaaa
     5701 ttccttatgc caactatgaa tctgttagaa atgcagtctt ctccttagag aaaagactgg
     5761 ctgacttagg tgttgacaga aaatcttgtc atatcgattt ggtgcctgaa aactttatcg
     5821 aatcacctca aggacgactt tatttgattg actgggaata ttcatcaatg aatgatccaa
     5881 tgtgggattt ggctgccctc tttttagagt ctgaattcac ttcccaagag gaagaaactt
     5941 tcttatctca ctatgagagt gaccaaacac cggtttctca tgaaaagatt gctatttata
     6001 aaattttaca agatactatt tggagtctat ggactgtcta taaggaagag caaggtgaag
     6061 attttggtga ctatggtgtg aatcgttacc aaagagctat taaaggtttg gcttcttatg
     6121 gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc ttctctcagg tattttctgg
     6181 ggcttgggtc taacggttag tgcttatatc ttttcgattt ttacagattt gtcacccttt
     6241 gtggtggctg caactcatga ttttttgagc atctttatct tactagcttt tctcttggta
     6301 aaagaaggga aagttcgcct ctcaattttc ttaaatattc gcaatgtcag tgttatcata
     6361 ggagccttgc tagcaggccc tatcggtatg caggccaatc tttatgcagt taagtatatc
     6421 ggaagttctt tagcttcatc tgtatcggct atttaccctg cgatttcagt tctattggct
     6481 ttcttctttt tgaagcacaa gatttcgaaa aatactgtat ttgggattgt cttgattatt
     6541 ggagggatta ttgcccagac ctataaggtt gaacaggtta attctttcta cattgggatt
     6601 ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga gtgttcttag ctcttttgcc
     6661 atggaaagtg aattgagtga aatcgaagcc ctcttaatcc gtcaagtaac ttcgttcttg
     6721 tcctatcttg tgattgtgct cttctctcat cagtcatttg ttgcagtagc caatggacaa
     6781 ttgctaggtc tcatgattgt ctttgtagcc tttgatatga tttcctattt ggcttattat
     6841 atcgctatca atcgcttgca accagccaag gctacaggct tgaacgtgag ctatgtagta
     6901 tggactgtct tgttcgcagc tcttttcttg ggaacatcat tagatatgct gaccattatg
     6961 acgtcacttg tcgtcattgc tggagtttat attattatta aagaataaag gagattcgtg
     7021 tgaaagccat tatcttagca gcgggattgg gaactcgctt gcgtcctatg actgaaaata
     7081 cccctaaagc cttggttcag gttaatcaaa aacctttgat tgaataccaa attgagtttc
     7141 tcaaagaaaa aggaatcaat gacatcatca tcatcgttgg ttatcttaaa gaacaattcg
     7201 attatttaaa agaaaaatac ggtgttcgcc tcgttttcaa tgataaatac gctgactaca
     7261 ataactttta ctctctctat cttgtaaaag aagaattggc caacagctat gttattgatg
     7321 ctgacaatta tctctttaaa aatatgttcc gcaatgattt gacacgttcg acttatttta
     7381 gtgtttatcg tgaagattgt accaacgaat ggttcttggt ctatggagat gactacaagg
     7441 ttcaagacat tattgttgat agcaaggcag gtcgcatcct tagtggtgta tccttctggg
     7501 atgctccaac tgcagaaaag attgtcagct ttatcgacaa ggcttatgca agtggtgaat
     7561 ttgttgatct ctactgggac aatatggtta aggataatat caaagagcta gatgtctatg
     7621 ttgaagaatt agaaggcaat agcatttatg agatcgatag tgtccaagac tatcgtaaat
     7681 tagaagaaat tcttaaaaac gaaaattaaa gattccaaca tctgacaaaa tagtcggatg
     7741 ttttttgatt ttttacgaat agatagatga gtagaaaaag aaatggagtt atttatgaaa
     7801 atcacaaact atgaaatcta taagttaaaa aaatcaggtt tgaccaatca acagattttg
     7861 aaagtgctag aatacggtga aaatgttgat caggagcttt tgttgggtga tattgcagat
     7921 atctcaggtt gccgtaatcc agccgttttt atggaacgtt attttcagat agacgatgcg
     7981 catttgtcga aagagtttca aaaatttcca tctttctcta ttttagatga ctgttatcct
     8041 tgggatttga gtgaaatata tgatgcgcct gtacttttat tttacaaggg aaatcttgac
     8101 ctcctgaaat tcccgaaggt agcggtcgtg ggcagtcgtg cttgtagcaa acagggagct
     8161 aaatcagttg aaaaagtcat tcaaggcttg gaaaatgaac tggttattgt cagtggtctg
     8221 gccaagggca ttgacacagc agctcatatg gcagctcttc agaatggcgg aaaaaccatt
     8281 gcagtgattg gaacaggact ggatgtgttt tatcctaaag ccaataaacg cttgcaagac
     8341 tacatcggca atgaccatct ggttctaagt gaatatggac ctggcgaaca acctctgaaa
     8401 tttcattttc ctgcccgtaa tcgcatcatt gctggacttt gtcgtggtgt gattgtagca
     8461 gaggctaaga tgcgttcagg tagtctcatt acgtgtgagc gagcaatgga agaaggacgc
     8521 gatgtctttg ctattcctgg tagcatttta gatggactat cagacggttg ccatcatttg
     8581 attcaagaag gagcaaaatt ggtcaccagt gggcaagatg ttcttgcgga atttgaattt
     8641 taaaaatgac ctaagctaga attctaagaa aaaatcaatt ttaagagaaa atgaacccaa
     8701 catttccata ataaaacgca tattagcaag tttttaacac ttgataatat gcgttttttc
     8761 taagtggatt agtagagtag aggatttttc tcatataata ctcttcgaaa atctcttcaa
     8821 actacgtcag cttccatctg caacctcaaa acagtatttt gagctgactt cgtcagtctt
     8881 atctacaacc tcaaagcagt gctttgagca acctgtggct agcttcctag tttgcgcttt
     8941 gattttcatt gagtataagg gaaagtatag tgaattgaaa taagatgtga acaactctat
     9001 caggaaagtc aaattgattt atagaaatat tttagcagcc aaggtgcact gttatagatt
     9061 caatacacta taatttagtg taattgagaa aggagaaatg attgtgattg atgttggcta
     9121 ggttatgttc aatgattcct accgtctcaa atcttgtcag taaggaaaaa taaattcttc
     9181 aaaagtagag attacaaggc ttgtttaaga aagaattcaa agaccttgac aaataaaaat
     9241 aaaatggtta ttataaaaaa tggtctgaaa tagatgatga tacttttcga aaatcttttt
     9301 acgtcagctc agctttgcct tgctgtgttt tgagcaagct acggttagct tccgagtttg
     9361 attttcattt actagaaatg aaactgatga gagatatcag tagacatttg agtcaggata
     9421 ttatggaaaa tgataaaaag agctcgtgag attggcatat cagactacta aagtattgag
     9481 tttgttagga ttttagcgac tagttagctg ggaaaggaag atatttgtga caaataataa
     9541 actgtattcg ttgatagaat ttagaaataa aatatatgaa gaattagaac tttccagaag
     9601 tgatttagcg attttactat gtgccatgct tatcgcctct atcggattaa atatggattc
     9661 gactcccgtg attattggag ccatgttaat ctctcctttg atgacaccta ttctgggagt
     9721 ggggctctct ctagctatat ttgattttaa attgttaaga aaatctttta aaatattagc
     9781 tattcaaatt cttgccagtc taatagcttc aacactttat ttttatcttt ctcccatttc
     9841 gtatgctagt tcggagattg ttgctagaac ctctccgact atttgggatg ttctcattgc
     9901 ttttgtagga gggatagcag gtattattgg tgctaggaaa aaagagacca ataatattgt
     9961 tcctggtgtt gctattgcaa ccgccttgat gcctcctctt tgtacagtag gttatgctat
    10021 tgcttctgct aatctaaaat ttatcatagg ctcctcttac ctatttctca tcaattgtag
    10081 ctttattgtc attgcgactt atataggtgt taggttgatg atggttaaga aacattattt
    10141 taaagataat gaagaagact ctaaaatgcg taggattttg cttctagttg ctgttttgct
    10201 gatgattccg agtttcatct ctgcaacgac tttagtgaga gaaacgttga aaaaagagtc
    10261 ccttaagaaa tttatatcag agcagtttca ggggcataat attttgaaaa aaacctattc
    10321 taaaaagact cataccctaa agctaaccat ttcaggaaat tatttgacag aagaagaact
    10381 cgatatgatt tcaagtaaga gaggtgacta tggtttaagt gatgtttctg ttcaagtttc
    10441 acaattgtct gattcagaac aacttagtaa ggaagaactg gtggagtatt tcttccagta
    10501 tatcaaggat aaggaagcaa aagaaaagga aaaagctaat aagttttata cagagtctga
    10561 ggagcaataa tttcttgaga atagctggtt tttctcgtga gtcttctatg tatatcaaag
    10621 gaagactgag gttttaagta taaaactttt cttctattat agtagctaag tcttgacagg
    10681 gttcaaaaaa tggtttacac tttataaagt ttattacttt gaaaaggtgt gatactgtgg
    10741 ctacggcaac aaaaaagaaa aaatcaacag ttaaaaaaaa tctagtcatc gtggagtcgc
    10801 ctgctaaggc caagacgatt gaaaaatatc taggcagaaa ctacaaggtt ttagccagtg
    10861 tcgggcatat ccgtgatttg aagaaatcca gtatgtccgt cgatattgaa aataattatg
    10921 aaccgcaata tatcaatatc cgaggaaaag gccctcttat caatgacttg aaaaaagaag
    10981 ctaaaaaagc taataaagtt tttctcgcga gtgacccgga ccgtgaagga gaagcgattt
    11041 cttggcattt ggcccatatt ctcaacttgg atgaaaatga tgccaaccgt gtggtcttca
    11101 atgaaatcac caaggatgca gtcaaaaatg cttttaaaga acctcgtaag atcgatatgg
    11161 acttggtcga tgcccaacaa gctcgtcgga tcttggatcg cttggtaggg tattcgattt
    11221 cgcctatttt gtggaagaag gtcaagaagg gcttgtcagc aggtcgcgtt cagtccattg
    11281 cccttaaact catcattgac cgtgaaaatg aaatcaatgc cttccagcca gaagaatact
    11341 ggacagttga tgctgtcttt aaaaagggaa ccaaacaatt tcatgcttcc ttctatggag
    11401 tagatggtaa aaagatgaaa ctgaccagca atgacgaagt caaggaagtc ttgtctcgtc
    11461 tgacgagtaa agacttttca gtagatcagg tggataagaa agagcgcaag cgcaatgctc
    11521 ctttacccta taccacttca tctatgcaga tggatgctgc caataaaatc aatttccgta
    11581 ctcgaaaaac catgatggtt gcccaacagc tctatgaagg aattaatatc ggttctggtg
    11641 ttcaaggttt gattacctat atgcgtaccg attcgactcg tatcagtcct gtagcgcaaa
    11701 ataaggcggc aagcttcatt acggatcgtt ttggtagtaa gtattctaag cacggtagca
    11761 aggtcaaaaa tgcatcaggt gctcaggatg cccatgaggc tattcgtccg tcaagtgtct
    11821 ttaatacacc agaaagcatc gctaagtatc tggacaagga tcagctcaag ctatataccc
    11881 ttatctggaa tcgttttgtg gctagccaga tgacagcggc cgtttttgat accatggctg
    11941 ttaaattgtc tcaaaatgga gttcaatttg ctgccaatgg tagtcaggtt aagtttgatg
    12001 gttatcttgc catttataat gattctgaca agaataagat gttaccggac atggttgttg
    12061 gagatgtggt caaacaggtc aatagcaaac cagagcaaca tttcacccaa ccgcctgccc
    12121 gttattctga agcaacactg attaaaacct tagaggaaaa tggggttgga cgtccatcaa
    12181 cctatgcgcc aaccattgaa accattcaga aacgttatta tgttcgcctg gcagccaaac
    12241 gttttgaacc gacagagttg ggagaaattg tcaataagct catcgttgaa tatttcccag
    12301 atatcgtaaa cgtgaccttc acagctgaaa tggaaggtaa actggatgat gtcgaagttg
    12361 gaaaagagca gtggcgacgg gtcattgatg ccttttacaa accattctct aaagaagttg
    12421 ccaaggctga agaagaaatg gaaaaaatcc agattaagga tgaaccagct ggatttgact
    12481 gtgaagtgtg tggcagtcca atggtcatta aacttggtcg ttttggtaaa ttctacgctt
    12541 gtagcaattt cccagattgc cgtcataccc aagcaatcgt gaaagagatt ggtgttgagt
    12601 gtccaagctg tcatcaggga caaattattg agcgaaaaac caagcgtaat cgcctcttct
    12661 atggttgcaa tcgctatcca gaatgtgaat ttacctcttg ggacaagcct gttggtcgtg
    12721 actgtccaaa atgtggcaac ttcctcatgg agaaaaaagt ccgtggtggt ggcaagcagg
    12781 ttgtttgtag caaaggcgac tacgaggaag aaaagattaa ataagaggag gggcccgaaa
    12841 gtaaatttca ggctcctttt ggttagaact tgacaaaata catcatttta tgcgaaacta
    12901 gaagaagatt attttatact caatgagaat caaagagcaa attagaaagc tagtcgcagg
    12961 ttgctcaaag cactactttg aggttgaaga tggaagctga cctggtttga agagattttc
    13021 gaagagtatt aactaggaga agttatgcgt cttatctatc tgataattgg ttttttatca
    13081 ctggccttgg ctattgttgg ggttgtttta cccttgttgc cgacaacacc tttccttttg
    13141 ttgtctattg cttgtttctc cagaagttcc aagcgattcg aagattggct ttatcatacc
    13201 aagctctatc aagcatatgt agctgatttt cgtgagacca agtctattgc gcgtgaacga
    13261 aagaaaaaaa tcatcgtctc tatctacgtc ttgatgggaa tttctattta ttttgcacct
    13321 cttttaccag tcaaaatcgg tctgggtgct ttgaccatct ttattactta ttatctcttc
    13381 aaggtcattc cagacaaaga atagttaaaa cagtagttat ttgccttgat aaaattgaaa
    13441 gcatattcat aacaatatga tataataaaa ttgaagtaat attcaaggag aatcaaatga
    13501 tttacgaatt ttgtgctgaa aatgtgactt tacttgaaaa agcgatgcag gctggagctc
    13561 gtcggattga actctgtgat aatctagcag ttggtgggac aacacccagc tatggagtga
    13621 ctaaggcagc ggctgaactg gcagctaact acgatacaac catcatgacc atgattcggc
    13681 cacgtggtgg tgactttgtc tataatgacc tagaaattgc tatcatgcta gaagacattc
    13741 gtttgactgc tcaggctgga agtcaagggg ttgtatttgg agctttaact gctgataaaa
    13801 agttggataa gcctaatctg gaaaagttaa ttgctgcatc aaaaggaatg gaaattgtct
    13861 ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc ggaagctatt gactggctca
    13921 gtcaagccgg tgtcactcgt atcctaactc gtgctggtgt gtctggcgac tccttagaaa
    13981 aacgttttgt tcactatcac agaattttgg agtacgctaa aggtaaaatt gaaattctac
    14041 caggtggggg gattgacctt gaaaaccgtc aaacctttat cgaccaggtg ggggtaacac
    14101 aattgcatgg tactaaggtt gttttttaaa aaatagaaag gaactgctag ctttgggtag
    14161 cagttttcac ttatgtttga aatttttaaa tcctatcaat ttaatcaaga aaaggctcat
    14221 gattatggtt ttatagaaaa tagcgaagtc tggacatata gttgccagat tttgcaaggt
    14281 gactttgtca tgactgtgtc catcactgct gataatgtga actttcaagt ctttgaccaa
    14341 gagactggtg acctctatcc tcacgtttat atggaaagca tgaggggaag ttttgtcgga
    14401 aatgtccgtg aggcttgtct ggagattctt taccagattc ggaaggcttg ttttgatgtg
    14461 caagatttta tctgtcatca gactaagcgt atcatgactc aagttcagga aaagtatgga
    14521 aaccagttgg agtatctgtg ggaaaaatcg cctgatacag ctgtattgcg ccatgaaggc
    14581 aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga ataagctgga aaagggcaga
    14641 gaaggacaag tggaagcagt caacctcaag catgaccaag tagctaattt gctttcacaa
    14701 aaggggattt atccagcctt ccatatgagc aagcgctact ggattagtgt gtcccttgat
    14761 gatactttat cagatgaaga agtactggaa ttgatagaaa aaagttggaa cttaacctct
    14821 aaaaaatgaa atattttaat aattttcatg aactttcaat tagctaaata ttctttactg
    14881 aagagatttt tagaaaatat aggatttacc acactagagg aatatggtgc catcttcaaa
    14941 tacctgattg agaatgtcaa gacggatcgt cagatcatct attcgcctca ctgtcatgat
    15001 gacctcggaa tggcagtggc aaatagcctt gctgctgtca agaatggtgc aggacgtgtt
    15061 gaagggacta tcaatggtat tagggagcga gctgaaaatg ctgctttgga agaaattgca
    15121 gtggctctca atattcgcca agattactac caagtagaaa ccagtattgt cctaaatgag
    15181 accatcaata cgtcagaaat ggtttctcgc ttctctggta ttccagttcc taaaaacaaa
    15241 gccgtcgttg gtggcaatac cttctcccac gaatctggta ttcaccaaga tggagtcctt
    15301 aaaaatcctc tcacttatga gatcatcaca cctgaattgg ttggtgttaa gattctgctt
    15361 ggaaaattat ctggtcgcca tgcttttgtt gagaaactga gagaattggc cctagatttt
    15421 acagaagagg atatcaaacc actctttgct aagttcaagg cactggtcga taagaagcaa
    15481 gaaatcacag atgcagatat tcgagctttg gtagctggaa ccatggttga aaatccagaa
    15541 ggcttccact ttgatgattt acaacttcaa actcatgcag ataatgacat tgaagcgctc
    15601 gttagcctag ccaatatgga tggtgagaaa gtcgaattta atgcgacagg gcaaggttcc
    15661 gttgaagcaa tctttaatgc tatcgataag ttctttaacc aatctgttcg tttggtgtcc
    15721 tacactatcg atgcggtaac agatggaatc gatacccagg atcgggtttt ggtcactgtt
    15781 gaaaacagag atacagaaac catctttaat gcagcagggc ttgattttga tgtgttgaag
    15841 gcttctgcta ttgtctatat aaacgctaat acctttgttc aaaaagagaa tgcaggtgag
    15901 atgggacgca gtgtttctta ccacgatatg cctagtgtgt aaaggagaag gctatggcaa
    15961 agaaaatagt agctctagca ggagacggaa ttggcccaga aatcatggag gttggtttag
    16021 aagttctgga ggctctagct gaaaaaacag gttttgacta tgagattgac agacgaccgt
    16081 tcggaggtgc agatattgat gcagcatgac ctcccttacc tgatgaaacc cttaaggcaa
    16141 gtagggaagc agatgctatc ctactagtag ctatcggtag tcctcagtat gatggagcag
    16201 tggttcgccc tgaacaaggc ctgatggctc tccgtaagga actcaatctt tacgctaata
    16261 ttcgtcctgt aaaaatcttt gacagtctca agcatttgtc actactcaaa ctggaacgaa
    16321 ttgctggtgt agactttgtc gtggtgcgtg aattgacagg cgggatttac tttggagatc
    16381 atattcttga agagcgcaat gcgcgtgata tcaacgacta tagctatgag gaagtggagc
    16441 ggattattcg caaagccttt gaaattgcaa gaaatcgcag aaaaatcgtt actagtatcg
    16501 ataagcaaaa tgttctagcg acctcaaaac tctggcggaa agtagctgag gaagtcgcac
    16561 aggatttccc agatgtaacc ttggaacatc agctggtaga ctcagctgct atgcttatga
    16621 ttaccaatcc tgctaagttt gatgttattg taacggagaa tctttttgga gatattttat
    16681 ctgatgaatc aagcgtctta tctggtacac ttggggttat gccatcagcc agtcattctg
    16741 aaaatggacc aagtctctat gaacctattc acagttcagc acctgatatt gcaggtcaag
    16801 gaattgccaa tcctatttcc atgattttat cagtttccat gatgttgaga gatagtttcg
    16861 gacgttatga ggatgcagag cgtatcaaac gtgctgttga gacaagtctg gcggcaggaa
    16921 ttttaacgag agatatagga ggtcaggctt caacaaagga aatgacggaa gctattattg
    16981 caaggttatg aagttagacg aaaaaattac tctagtcctt ttgatttgga atgtcatcat
    17041 tttcttgatt tatggtattg acaaatctaa ggcaaggaga agagtttggc gcatccctga
    17101 gaaaatctta cttattttag cctttacttt tggtggtttt ggtgcctggc tagcaggaat
    17161 catctttcac cacaagactc gaaaatggta ctttaaaata gtttggtttc ttgggatggt
    17221 gaccacacta gtagccttat attttatttg gaggtaatgg atggcagggt cttcgaggga
    17281 atacgctgct tgggctctag cggactatgg ttttaaggtc gtgattgcag gatctttcgg
    17341 tgacattcat tacaataatg aactcaataa tggcatgttg ccaatcgttc agcctagaga
    17401 ggttagagag aaactagccc agctaaaacc aaccgaccag gtaactgtgg acttggaaca
    17461 acaaaaaatc atctcaccag ttgaagaatt caccttcgag atagatagcg agtggaaaca
    17521 taaactccta aatagtttgg atgatatcgg tattaccttg cagtatgaag agttgattgc
    17581 tgcttatgaa aaacaacgac cagcctactg gcaggattag aaaaaataga aaaggagata
    17641 tagtaaactg aaataagatg taaacaaatg aattggagct taacatccat ttccagcaat
    17701 tttttagaaa ctacagtgga ctattctgga ttcaacacat tataaaatta tgacaaaaca
    17761 cattcacaag aaggctacga cattttaaaa ggtgagggcg gatgtatcgt ttgccctact
    17821 aaagttggtt acattatcat gaccagtgac aaggcaggac ttgagcgtaa gttcgcagcc
    17881 aaagaacgta agcgtaacaa accaggtgtt gttctctgcg gtagcatgga tgaactttgc
    17941 gctttagcgc aactcaaccc agaaattgaa gcattctact aaaaacattg ggatgaagat
    18001 attcttcttg gttgtatcct tccttggaaa ccagaagcct ttgaaaaact caaagcatac
    18061 ggggatggcc gtgaagaact tattactgat gtacgtggta ctagctgttt tgttatcaag
    18121 tttggaaaag caggtgaaca attggctgcc aagctttggg aagaaggtaa aatggtctac
    18181 gcctcatctg cttcaatgac aaaacgattg aaactcgcta tgagcaaggt gtaatggtgt
    18241 ctatggtcga taaggacggc aaactcatcc cagaacaagg aggagcacgt tcaacttcac
    18301 cagctccagt tgtgatccgt aaagggcttg acattgataa aatcatgatg cacctgtcag
    18361 atacttttaa ctcatgggac taccgtcagg ttgagtatta ttaggataga gaagaagtct
    18421 agtgttatga gatattaaag ctcctaacac tgggcttttg tttagaattt cttttctttt
    18481 tctataggat atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa
    18541 acatcattag taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt
    18601 tataaatggt atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag
    18661 tttaatgata aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca
    18721 atgtcaatcg atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct
    18781 cttgagaagg gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa
    18841 tttggtattt attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt
    18901 tcagagttgg atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa
    18961 ggtattcgtt ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt
    19021 attggtcgtt ctgctatggt gacaaaatta ctttgtatct atactgaggg agatcctttc
    19081 tttggtgtaa atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat
    19141 caaggtggac cttatctgca aaatcataaa ataattgaac tggtgtccaa aacttatcct
    19201 gagttggagc catcgaaatt aggaactatg ctttttgagt attctaagct ttttatggaa
    19261 aataaggaag acaatagtac aatggattca tcaaacaatt ttagtcatca attaactcaa
    19321 tctctattaa agtctccaaa ccttatcctt cgtggtgctc ctggcacagg aaagacttat
    19381 cttgctaaag aaattgccaa agaattaacg gatggtaacg aagaccaaat cggatttgta
    19441 caatttcacc catcctatga ttatacggat tttgtagaag gtttaagacc agtatcaaat
    19501 ggggatggag ctattgagtt taggctacag gacggtattt ttaaagattt ttgtcagaaa
    19561 gcaaaagaaa cccaattgat tggaggacaa gataattttg atgaggcttg ggattcttac
    19621 ttagaatata taaatgttgc tgaagaaaaa gaatatataa caaaaacatc ttacttatct
    19681 gttaatagta gacaaaattt gtcagtaaat tatgatagtg gtgttccagg atggtcacta
    19741 cctagcaaat atgtttacga gttgtataaa gataaaaatt ataataagca agaatactac
    19801 aaaagtggtg gaaaaactgt cctagaaaca ttgagaaaga gatttggttt gaaagactat
    19861 atttctccag aagaggttga aacagacaag aaatttgttt tcatcatcga tgagatcaat
    19921 cgtggggaga tttctaagat ttttggcgaa ctcttttttt ctatcgaccc tggctatcgt
    19981 ggtgaaaaag gaagtgtttc tacccaatat gcaaatctac acgaaactga tgaaaagttc
    20041 tatatccccg aaaatgttta catcatcgga actatgaatg atattgatcg ttcagtggat
    20101 acctttgatt ttgctatgcg tcgtcgtttt cgttttgttg aagttactgc cgagggtcaa
    20161 gttggcatgt tggataaaga gctgaatatc catgcagaag aagcaaaaat tcgtctaaga
    20221 aacttgaacg ctgctatcga aaatgttcag gaattaaaca gtcattatca tattggacca
    20281 agttattttc ttaagttgaa ggatgtagat tttgactatg aattactctg gtctgattat
    20341 attaagcctc tcctagaaga ctacttgcga ggttcttatg atgaggttga aactttggaa
    20401 actttgaaaa aagcatttga actgacaaat aatgagcaaa aagatcaggc agtagctgat
    20461 gacaatgaag gtgatgaaaa cgatgatgcg gattactgat aatcaacaca agattattaa
    20521 agaaaaattt gttgaagaat atcctaaact aagcaatctt cttttagaca gaaccttgga
    20581 aagtctatcc caagatgaac gtattttcat ttttccaaat gatttgactc atactcctga
    20641 tttggataag gatcaaaaga tttttgaaac agtcaatcag aaaatcaaga cagggaacgt
    20701 gattggtttt cttggatatg gtcaggaaag attaacgatt tcctcacgat tttctgatga
    20761 gagtaatgac cattttttgc attatctctt aaacaaggtt ctttatatca atctcactag
    20821 tttagatgtt gctttgtctc gtgaagagag gctttatcaa cttttgatgt atctcttccc
    20881 caagtatcta caagctgcta ttcgaaaagg tctttataag gaatatcatc gattttctca
    20941 taacgacagt aatgttaagg gagtgattgt tgtaagaaac catctcaaga aaaatcttcc
    21001 tttcacggga aatattgcct acacaacgag agagttcacc tatgataatc ccctcatgca
    21061 gttggtccgt cacactattg aatacattaa gaatcagaaa agcattggtc aaggggtact
    21121 agataatctc tcaactagtc gtgaaaacgt atctgaaatc gtgcgtgtaa cgccctctta
    21181 taaactagct gatcgtgcta agattactcg gagaaatcaa tctaaaccta tacgtcatgc
    21241 atactttcac gagtacagaa acttacaaga actttgtctg atgatcctaa accaagaaaa
    21301 gcacggttta gggtatcaag atcaaaaaat ctatggtatt ctctttgatg ttgcctggct
    21361 ttgggaagag tatgtttaca ccttgttgcc aaaaggtttt gtacatccca gaaataagga
    21421 taagacggat ggaatttcag tattttctgt tgggaaacga aaagtatatc cagattttta
    21481 tgacagagaa cgaaagattg ttctagatgc aaaatataaa aaactggaat tgactgaaaa
    21541 aggaatcaac cgtgaggact tattccagct gatttcctat tcttatattt taaaagctga
    21601 gaaggctgga cttgtttttc cgagcaagga caaggtcatt gataatgaga taggaaacct
    21661 agcaggttat ggagctttgt tgaagaaatg gtctatccaa attcctcaga agtcttcatc
    21721 ttatagtgca ttttgtaaaa tgatggaaaa ttcagaagaa aattttaaag cgattattga
    21781 tgaagaagtg gggagaaaat aatttcccct ctttctttta tttttaacac aagcaaaatc
    21841 cgaacaatat attttaattc ataaaataat ttgacaaaaa ctgtactttg gtttataata
    21901 aattaaggaa acgtcggaaa aggcgtagtg atgcgagagc ataggtaggt cattacaaaa
    21961 gaaacgagac atcgatatgt taaatgaatt tccaattttt gattacgaag atattcaatt
    22021 gattccaaat aaatgtgtca ttaaaagccg tgcagaagcg gatacaagtg tcactttagg
    22081 aaatcacacc tttaaactac ctgttgtgcc agcgaatatg cagacgattt tggatgaaaa
    22141 tgtagcagag caactggcta aaggtggtta cttctacatt atgcaccgtt ttgatgaggc
    22201 aggacgcatt ccttttatta aacgaatgca cgatcaaggg ctcattgctt ccatatctgt
    22261 cggtgttaag gattatgagt atgattttgt tagccagctc aaggctgatg ctcctgagta
    22321 tatcactatt gatattgctc atggtcatgc ggagagcgtg atttctatga ttcaacacat
    22381 caagaaagaa ttgccagata cctttgtcat tgctggaaat gtgggaacac cagaagctgt
    22441 gcgtgaattg gaaaatgctg gtgcagatgc tactaaggtc ggaatcggtc ctggtaaggt
    22501 ttgtatcacc aaggttaaga ctggttttgg tacaggtggt tggcagttgg ctgctctacg
    22561 ctggtgtgcc aaggctgcgc gtaaaccgat tatcgctgat ggaggaattc gtactcacgg
    22621 tgatattgcc aagtctatcc gcttcggtgc tagcatgatc atgattggtt ccctctttgc
    22681 aggacacatt gaaagtccag ggaaaacgat tgaagtcgat ggtgaacagt tcaaagaata
    22741 ttatggttca gcctcacaat atcagaaagg tgcttacaaa aatgtggaag gcaaacgtat
    22801 cttgcttcct gctaaaggtc atctgcaaga cactttaact gagatggaac aagaccttca
    22861 aagtgctatt tcttatgcag gtggacgtca ggttgctgac cttaaacacg ttgattatgt
    22921 gatcgtgaaa aactccatct ggaatgggga tgcttcccac taagacgggg tctttgacca
    22981 aaaaacttgt tattagagca aatttctgtt ataataaaac aagtttccac ccttagtgta
    23041 atggatatca cgtaagattc cggttcttga gatgggggtt cgattccctc agggtggatg
    23101 taaacatcct aaaaagcctt taatagggct tttttcttta tcctgaccca aatttgccgc
    23161 taaaactgag aatctctgtc taaagaattc ccaaatgctt tccagtcccg ttttagagtg
    23221 actcaggggg ctttttttga tataataaaa aggactatta tcagttagaa agaagttggt
    23281 atgaaagaat tacaaactgt actaaagaat cattttgaaa tcgaatttgc agacaaaaag
    23341 ttactggaaa ctgcctttac tcatacgagt tatgccaatg agcaccgcct cttaaaaatt
    23401 tcacacaatg aacgcttgga atttttagga gacgctgttc tacagttatt gatttcagaa
    23461 tatctatata aaaaatatcc taaaaagcct gaaggtgacc tatcaaaact ccgtgctatg
    23521 attgtccgtg aggagagttt agctggtttt gcgcgtgatt gccagtttga ccagtttatc
    23581 aagttgggta aaggggaaga aaaatctggt ggtcgcaatc gtgacaccat tcttggtgat
    23641 gcctttgaag cctttcttgg tgcccttctt ttggataagg atgtggcaaa ggtcaaggaa
    23701 tttatctacc aagttatgat tcctaaggta gaagcaggcg aatttgagat gattacagac
    23761 tataaaaccc atctccaaga gttgcttcag gtcaatggtg atgtggctat tcgttatcaa
    23821 gtgatttctg aaacagggcc tgctcacgat aaggtctttg atgtagaagt tcttgttgaa
    23881 ggtaagagca tcggtcaagg ccaaggtcgt tctaagaaat tagcagagca ggaagctgcc
    23941 aaaaatgccg ttgagaaagg gctggattca tgtatttaaa ggaaatcgaa attcaggggt
    24001 tcaagtcttt tgctgataag accaaggtcg tttttgacca aggtgtgacg gcagttgttg
    24061 gacccaatgg atctggaaag tccaatatta cagaaagtct gcgttgggct ttgggggagt
    24121 ctagtgtcaa gagtctccgt gggggcaaga tgccggatgt catctttgct ggaacagaaa
    24181 gtcgcaaacc gctcaattat gcttctgtag ttgtgactct ggataatcat gacggattta
    24241 tcaaggatgc aggtcaagaa atcagggtgg aacgccatat ctatcgtagt ggagatagcg
    24301 aatacaagat tgacggcaag aaagtccgtc tgcgtgatat tcatgacctc ttcttggata
    24361 ctggattggg acgagattcc ttctctatta tttcccaagg gaaggttgag gagattttta
    24421 attccaagcc tgaggaacga cgagctattt ttgaagaagc tgctggagtt ttaaaataca
    24481 agactcgcag aaaagaaacc gagagtaaac tgcagcaaac tcaggataat ctggaccgct
    24541 tagaggacat tatctacgag ttggataatc aaatcaagcc tcttgagaag caagctgaga
    24601 atgcccgtaa gtttttagac ttggaaggac aacgtaaggc tatttattta gacgttctgg
    24661 ttgctcaaat caaggaaaat aaggcagaac tagagtcgac agaagaagag ttggctcagg
    24721 ttcaagaact cttgatgagt tattaccaaa agcgtgaaaa attagaagaa gaaaatcaaa
    24781 ctcttaaaaa gcaacgccaa gatttacagg ctgaaatggc caaagaccaa ggcagtttga
    24841 tggacttgac tagtctgatt agtgatttag aaagaaaatt agccctatcg aaactggagt
    24901 ccgagcaagt ggccctgaat caacaggagg cacaagctcg tttggctgct ttggaggata
    24961 agagaaattc actcagcaaa gaaaagtatg ataaagaaag ctctttagct ctgttagagg
    25021 gaaatctagt ccaaaataat caaaaactca atcgtttaga agctgaattg ctggctttct
    25081 cagacgatcc tgatcagatg attgagctct tacgtgaacg ctttgtagct cttttacaag
    25141 aagaagcgga tgtctcaaac cagttgaccc gtattgagaa tgagttggaa aatagtcgtc
    25201 agctttctca aaaacaagca gatcaactag aaaagctgaa agagcaatta gctacagcta
    25261 aaaagaaggc tagtcagcaa aaagacgagc ttgaaactgc caaggtgcag gttcagaaat
    25321 tattggctga ctatcaagct attgccaagg agcaagagga gcagaaaact tcctatcaag
    25381 ctcaacaaag tcaactcttt gaccgtctgg atagtctcaa aaacaagcag gccagagctc
    25441 aaagtttgga aaatatcctg agaaatcata gtaactttta tgcaggtgtt aagagtgttc
    25501 tccaagaaaa agatcgccta ggtgggatta ttggtgcagt cagtgagcat ctgacctttg
    25561 atgtttatta tcaaactgcc ctagagattg ccttaggggc aagtagccag catatcatcg
    25621 tagaagatga agagtcggca accaaagcta ttgatttcct caaacgaaac agagtcggtc
    25681 gtgcaacctt tcttcctttg accactatta aggcgcgtac gatttctagt cagaaccaag
    25741 atgctatcgc tgtaagccca ggtttccttg ggatggcaga tgagttggtg acttttgata
    25801 ctagactgga agccattttc aagaacttgc tagctacgac ggctatcttt gataccgtag
    25861 aacatgcgcg tgaagctgct cgacaagttc gttatcaggt tcgtatggtg acattggatg
    25921 ggacagaatt acgcacgggt ggttcctatg cgggtggtgc caatcgccaa aataacagta
    25981 ttttcatcaa gccagaactg gagcaattac aaaaagaaat tgctgcagat gaagcaagct
    26041 tgggttcaga agaagcggct ttgaagacct tgcaagacca gatggctgca ttgacagaaa
    26101 gattagaagc catcaaatct caaggagagc aggcacgtat tcaggagcaa ggcttgtccc
    26161 tcgcttatca gcaaactagt cagcaagttg aagaactgga aactctttgg aaactccaag
    26221 aagaggaaat agatcgtctt tctgagggag attggcaagc ggataaggaa aaatgtcaag
    26281 agagccttgc tactatcgcc agtgaaaagc aaaatctgga agctgagatt gaagaaatta
    26341 agtctaataa aaacgccatc caagaacgct atcaaaattt gcaggaagag gtggcgcaag
    26401 ctcgcttgct taagacagaa ctgcaagggc aaaaacgtta tgaagtagct gatattgagc
    26461 gtttaggcaa ggaattggac aatcttaata tcgaacaaga agaaattcag cgcatgctcc
    26521 aagaaaaagt tgacaatctt gagaaggttg atacagaatt gctcagtcaa caggcggaag
    26581 aatccaaaac tcagaaaaca aatctccaac aaggtttgat tcgcaagcag tttgagttgg
    26641 atgatataga aggtcaactg gatgatattg ccagtcactt ggatcaagct cgccagcaga
    26701 atgaggagtg gattcgcaag caaacacgtg ctgaagccaa gaaagaaaag gtcagcgagc
    26761 gcttgcgcca tctacaaaat caattaacag accagtacca gattagctat actgaagcac
    26821 tagaaaaggc acatgaattg gaaaacctca atctggcaga gcaagaggtg caggatttag
    26881 agaaggctat tcgctcattg ggacctgtca acttggaagc tattgaccag tacgaagaag
    26941 ttcacaaccg tctggacttt ctaaatagtc agcgagatga tattttgtca gcgaaaaatc
    27001 tgctccttga aaccattaca gagatgaatg atgaggtcaa ggaacgcttt aaatcaacct
    27061 ttgaagctat tcgtgagtcc tttaaagtga ccttcaagca gatgtttggc ggaggtcagg
    27121 cagacttgat attgactgag ggcgaccttt taacagctgg tgtggagatt tctgttcaac
    27181 ctccaggtaa gaaaatccag tcgcttaacc tcatgagtgg tggtgaaaaa gctctatcgg
    27241 ctcttgcctt gcttttctcc attattcgtg tcaagaccat tccttttgtc atcttggatg
    27301 aggtggaagc tgcgctggat gaagccaatg ttaaacgttt tggggattac ctcaaccgct
    27361 ttgacaagga cagccagttt atcgttgtaa cccaccgtaa gggaaccatg gcagcggctg
    27421 attccatcta tggagtgacc atgcaagaat cgggtgtttc aaagattgtt tcagttaagt
    27481 taaaagattt agaaagtatt gaaggatgac aattaaacta gtagcaacgg atatggacgg
    27541 aaccttccta gatgggaatg gacgctttga tatggatcgt ctcaagtctc tcttggcttc
    27601 ctacaaggaa aaagggattt actttgcggt ggcttcgggt cggggatttc tgtctctgga
    27661 aaaattattt gctgatgttc gtgatgacat tattttcatc gcggaaaatg gcagtttggt
    27721 agagtatcaa ggtcaggact tgtatgaagc gactatgtct cgtgactttt atctggcaac
    27781 ttttgaaaag ctgaaaacgt caccttatgt agatatcaat aaactgctct tgacgggtaa
    27841 gaagggttca tatgttctag atacggttga tgagacctat ttgaaagtga gtcagcatta
    27901 taatgaaaat atccaaaaag tagcgagttt ggaagatatc acagatgaca ttttcaaatt
    27961 tacaaccaac ttcacagaag aaacgctaga agctggtgaa gcttgggtta atgaacatgt
    28021 ccctggtgtt aaggccatga caactggctt tgaatctatt gatattgttc tggactatgt
    28081 cgataagggt gtagctattg ttgaattagc taaaaaactt ggtatcacaa tggatcaggt
    28141 catggctttt ggagacaatc ttaatgactt acatatgatg caggttgtgg gacatcctgt
    28201 agctcctgaa aatgcacgac ctgaaatttt agaattagca aagactgtga ttggtcacca
    28261 taaggaacgg tcggttatag cttatatgga gggcttataa tggcagatat aaaattgatt
    28321 gcattggact tggacgggac cttgctgact actgataaaa ggctgacgga tcgtaccaag
    28381 gaaaccttga aagctgcgcg tgatcgtggt atcaaggtcg tattgacaac tggtcgtccc
    28441 ttaaaagcca tggatttctt tctccatgag ttagggactg acggtcagga agatgagtat
    28501 accattactt ttaatggtgg attagttcag aaaaatacag gagaaatcct tgataaaaca
    28561 gtcttttcat atgatgatgt ggcacgtttg tatgaagaaa cagagaaatt atcactgcct
    28621 cttgatgcca tctcagaagg aacagtttat caaatccaat cggaccaaga aagtctttat
    28681 gccaaattca atccagcttt gacctttgtt ccagtggact ttgaagactt atctagtcaa
    28741 atgacctaca acaaatgcgt gactgccttt gctcaagaac ccttggatgc agccattcag
    28801 aagatttctc cagaattgtt tgaccaatat gaaatcttta aatcacgtga aatgttgcta
    28861 gaatggtcac caaagaatgt tcataaagca acaggtttgg caaaactaat cagccatctt
    28921 ggaatcgacc aaagtcaagt gatggcttgt ggtgacgagg ccaatgacct ctctatgatt
    28981 gaatgggcag gtcttggtgt tgctatgcaa aacgctgttc ctgaagtaaa ggcagccgca
    29041 aatgtagtga cgccgatgac caacgatgag gaagctgtcg cctgggctat cgaagaatat
    29101 gtgctaaagg agaactaaga tatgggattg tttgaccgtc tattcggaaa aaaagaagaa
    29161 cctaaaatcg aagaagttgt aaaagaagct ctggaaaatc ttgatttgtc tgaagatgtt
    29221 gatcctacct tcacagaagt tgaggaaatt tctcaggaag aagcagaggt tgaaattgtt
    29281 gaacaagctg tgttccaaga agaggaaatc caagacacag ttgaagaaag tctggattta
    29341 gagccagttg tagaagtttc tcaaaaagaa gtcgaagaat ttccacactc agaagaaggg
    29401 aatactgagt ttctagagac tatagaagaa aataattctg aagttcttga accagaaagg
    29461 cctcaagcag aagaaaccgt tcaggaaaaa tatgaccgca gtcttaagaa aactcgtaca
    29521 ggtttcggtg cccgcttgaa tgccttcttt gctaacttcc gctctgttga cgaagaattt
    29581 ttcgaggaac tggaagaact gctgattatg agtgatgttg gtgtccaagt cgcttctaac
    29641 ttaacggagg aactacgtta cgaagccaag cttgaaaatg ccaagaaacc tgatgcactt
    29701 cgtcgtgtca tcattgagaa attggttgag ctttatgaaa aggatggtag ctacgatgaa
    29761 agcatccact tccaagataa cttgacagtt atgctctttg ttggtgtgaa tggtgttggg
    29821 aaaacaactt ctatcggaaa actagcccac cgctacaaac aagctggtaa gaaggtcatg
    29881 ctggttgcag cagatacctt ccgtgcgggt gcagtagctc agctagctga atggggccga
    29941 cgagtagatg ttccagtagt aactggacct gaaaaagctg atccagccag cgtggtcttt
    30001 gatggtatgg aacgtgccgt ggctgaaggt atcgatattc tcatgattga tactgctggt
    30061 cgtctgcaaa ataaggataa ccttatggct gagttggaaa agattggtcg tattatcaaa
    30121 cgtgttgtgc cagaagcacc acatgaaacc ttcttggcac ttgatgcatc aacaggtcaa
    30181 aatgccctag tacaggccaa agaattttcg aaaatcacac ctttaacggg aattgttttg
    30241 actaagattg atggaactgc tcgaggaggt gtggttctag ccattcgtga agaactcaat
    30301 attcctgtaa aattgattgg ttttggtgaa aaaatcgatg atattggaga gtttaactca
    30361 gaaaacttta tgaaaggtct cttggaaggt ttaatctaat cagaagcaaa aatcctgcaa
    30421 ggcataaact tgcaggaaat ttttttattc taagcgacca tcttgacgat aggtgatatc
    30481 tggttgccaa gtccatttgg caccgaattt tttaagtagg tcaaagctgg cttgaggtcc
    30541 catgcttcca gctttatagt catgaagtgg ggcaccattt tcagcccaga gcttttcaat
    30601 acggtcaatc aacttccatg acgcacaaac ttcatcccag tggctaaagt tagttgagtt
    30661 gttatttagg acatcataaa tcaatttttc gtatggttct ggagaagtac cagttgcagt
    30721 cgcatctgta cggtaatcaa gtgagttagg agccaagtta aattcttctc ctacttgctt
    30781 cccatttagg ctaagagaga agccttctgt tggttgaata tagatggtca aaatatttgg
    30841 agcaagtggt tctccaaaga tagaatccat ttgtttaaag acgatgttga catgagttcc
    30901 tttttcagtc agtcgtttac ctgtacggaa aaagaaagga acaccacgga atcgatcgct
    30961 gtctacaaag aaggcaccag atgtaaaggt ttcagttgtt gattctggat tcacatttgg
    31021 ctcgctacga taagagatgt atttcatgcc atcaatctta ccagagcggt attgcccacg
    31081 gataaagtgt tctttgagtt cttcatcagt tggatgatag aggtttttaa agaccttaat
    31141 cttttcagca cgaatctcgt cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga
    31201 aagaagttgt agagtgtggt tttggaccat gtcacggagg gcaccggatt ggtcatagta
    31261 gccaccacgt tcttctacac ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa
    31321 atccttgttc caaacgtttt caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg
    31381 gatcatttcc ttaccaagat aatggtcgat acggaaaatt tgttcttcgt caaatgttgc
    31441 taggagttcg tcattcaact tgtttgcagt tgcgtaatct gtaccaaatg gtttttcaac
    31501 gatcaagcgc tcaaaacctt tgccatcgac aatgttttca gatttgaggt gtttggcaat
    31561 ggttccaaag aactgaggtg ccatagacaa gaagaagagc ttattgtgtt cagcttggta
    31621 tttttcatta agctcagctt gtaattgacg caaagcaata taatgttccg aatcattgac
    31681 atcatggctt tgatagtaga agtggctagc aaattcttgg gcttgctcgg tactatctgc
    31741 caaatcaagg atggactcga caactacaga ttcaaaatat tccttactcc aaggtctacg
    31801 ggcagttcca ataacggcaa agtgcttgga aagattgccg gatttatata gtctaaaaag
    31861 ggaagggtag agcttgcgtt tagccaggtc tccactcgca ccgaaaattg taacaataac
    31921 cttagatgac atctagctac ctaatttcta tttttattcc tagtcttgct aggtatgagg
    31981 aaacctcatt tcataaactt aattctaaca taattttccg aaaaatcaaa aattccaata
    32041 cgaggtagaa aaactgcaag gaaatcctta cagtttgagt ttagacgttt aagaccttat
    32101 ctaagaactc tttcagacga gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt
    32161 cttcaaggaa ctcgccatct gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc
    32221 ccatctcatg ggttacgata atcatggtca tgccttgctc agccaattcc ttcataacgt
    32281 taagtacgtc tccaaccatc tcagggtcaa gggcagaagt tggttcatcg aagagcatga
    32341 tgtctggatt cattgctagg ccacgagcta tggccacacg ttgtttttga ccacctgata
    32401 ggctatctgg attggcatta gctttatctg ctagtccaac cttttcaagc aactccattc
    32461 ccaatttctc agcttcttcc ttagtcatca acttgtgctc aataggagca aaggtgatgt
    32521 tgtccaatac agacatatga gggaagaggt tgaagtgttg gaataccatg ccgatatttt
    32581 cacggacgtg gtcaacattg gttgtttttt cagttaaatc atagccgttc acagtgatgt
    32641 gaccgctagt gacttcttct aaaagattga ggctacggag gaaagttgac ttaccagaac
    32701 ctgaaggacc gatgatacaa acaacatctc cttcatagaa cttagtcgta attcctttta
    32761 ggacttcatt ttttccatag tgcttgtgta aatcatttac atcaattttt aattttgcca
    32821 ttaacgaatc ctcttttcta agcgtttcgc tagtctagtc aaaagtgtga taattacaag
    32881 atagaagata gcaaggattg catacatctt gaaactttgg tagttacgag caatgataat
    32941 cttaccagtt tggaagagtt caaccaaacc gatagcagat acgatagttg tatctttaag
    33001 agcgataacg aattggttga caaagtttgg caacatcaat ttagttgctt gtggcaagat
    33061 aatcttacgc atggtttttc cataagagat acccaagctt cggctggctt ccatttggcc
    33121 aactggaacg gcctgaatac caccacgaac gatttcagcg atataagcag ccgcattgag
    33181 tgagagggca atggttccag ctacaaagtc gttaattggg ctttgttggc ctgtgataga
    33241 ctcgatgaag tttggaattc cccagaagat gaaggctgca agaatcatca atggaatacc
    33301 acgaataacg tcaacgaaaa tctcagagat gacgcgaaga gatttgtatg ggctaacgct
    33361 aaacataccg aagataattc cgatgacaat ggcaatagca aatgagataa gagctagagc
    33421 aagagtgata ccaagaccgc taaggagttg tttgtagttg ttttgaagca agccccagag
    33481 cgttgtttcg tcaacagtac ttgttgaagc agttgaagat tcgctagcta ggtatttgtc
    33541 aagaatcttt tggaattcac cgtttgcttt aaggtttgca agtccgttgt tgaacatttc
    33601 aatcagttct ggatttgctc cttttttaac ggcaaaggct gtttcaccga ttggagttcc
    33661 agagattgga gttttcaatt tttgaccttg gctgatagaa tatttgagaa caggttcatc
    33721 atccataacg gcatcaatgg caccagtgtt taaactgtca tacattgaag aaccatcagc
    33781 aaaggttttg attttgtagc cgtatttgct ttgattttct gttaggaagg tttgagaagc
    33841 agttccgttt ttaacaccga ctgtctttcc ttttagatct tcataagaag caatattact
    33901 tgattctttg acaccaagaa tggtattagc agtgtagtat gattctgaga agtcaaaagt
    33961 tgccttacga gcatctgtga cagacatacc agcgatgata ccatcggctt gaccagcttg
    34021 gacagcactg atagcagcat caaaaccagg gttggtgatt tcaatttcaa aaccttggtc
    34081 tttagcgatt gccttaatca attccatatc aataccagtg tattgattgc ttgaattttg
    34141 gaaaacaaaa ggtgcaaaag aagaatcgct ggcaatgata tatttagcct taacaggaat
    34201 agcttttaat cctgcgagag tagttgtagt tggcactgct gaagatgatg aagcagtcca
    34261 tttcttgata attttatcaa gactaccatc ttttttcatt tcagccaagg cttggttaaa
    34321 ttcagtaacc aggtgctcgt atttacttcc ttttttcaca ccgaaagcaa aacttcctac
    34381 agcttcacca tccatttcaa tatggaggtc ttgaccttgg ttaatggcat attcgataac
    34441 aggtttgtca tccatcatgg catcgatggc accagcactc aagctgttgt tcattaaatc
    34501 accagtgtca aatgttttaa tagtaaagcc gtatttatct ttgattgttt caaggaaacg
    34561 ttgagcggca gttccgtttt taacaccaac ggttttgcca gttaattggt cgtacttgct
    34621 aattttgtgt gactttgtag tagcaatgac aacttttgta tcatagtaag tatcagacat
    34681 ggtgaagact ttttcacgtt ctttagtctt tgtcatccct gccatgatag cgtcggcttg
    34741 cccagcttga accgcattga ctgctgcgtc aaatccagga taggacatct gaatgttcca
    34801 gcctttaatc tcagcgactt tgttaataat gtcaacatca attcctttat aagtttgatc
    34861 tgaatcttta aactcaaaag gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc
    34921 tttggcaata cctaatgaga aaattgggaa taaaattagc aaaaatgcta gaaatttttt
    34981 cttcattttt agtctccttt tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag
    35041 gcaaattttt atatttttcg tgtcag
//
LOCUS       DAVMCN010000015        34423 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVMCN010000015 DAVMCN010000000
VERSION     DAVMCN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.015"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            110..2002
                     /gene="pepO"
                     /locus_tag="VYP85_000905"
     CDS             110..2002
                     /gene="pepO"
                     /locus_tag="VYP85_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1881441.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2125..2754)
                     /locus_tag="VYP85_000906"
     CDS             complement(2125..2754)
                     /locus_tag="VYP85_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1881442.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKYLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFHFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGSATTIAHEKAFNPFF"
     gene            3750..5972
                     /locus_tag="VYP85_000907"
     CDS             3750..5972
                     /locus_tag="VYP85_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1881443.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6002..6445
                     /locus_tag="VYP85_000908"
     CDS             6002..6445
                     /locus_tag="VYP85_000908"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1881444.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6712..6897)
                     /locus_tag="VYP85_000909"
     CDS             complement(6712..6897)
                     /locus_tag="VYP85_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881445.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(6916..7329)
                     /locus_tag="VYP85_000910"
     CDS             complement(6916..7329)
                     /locus_tag="VYP85_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881446.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7460..8167)
                     /locus_tag="VYP85_000911"
     CDS             complement(7460..8167)
                     /locus_tag="VYP85_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1881447.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGL
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQISQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(8286..8936)
                     /locus_tag="VYP85_000912"
     CDS             complement(8286..8936)
                     /locus_tag="VYP85_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1881448.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMVIAKQLYVEKIN"
     gene            9048..9890
                     /locus_tag="VYP85_000913"
     CDS             9048..9890
                     /locus_tag="VYP85_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1881449.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQLHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDNGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9966..10403
                     /locus_tag="VYP85_000914"
     CDS             9966..10403
                     /locus_tag="VYP85_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1881450.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10472..10774
                     /locus_tag="VYP85_000915"
     CDS             10472..10774
                     /locus_tag="VYP85_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881451.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSFISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10865..11938)
                     /locus_tag="VYP85_000916"
     CDS             complement(10865..11938)
                     /locus_tag="VYP85_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1881452.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPSQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPK
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            12094..12771
                     /locus_tag="VYP85_000917"
     CDS             12094..12771
                     /locus_tag="VYP85_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881453.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12764..13738
                     /locus_tag="VYP85_000918"
     CDS             12764..13738
                     /locus_tag="VYP85_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1881454.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13787..15730)
                     /gene="thrS"
                     /locus_tag="VYP85_000919"
     CDS             complement(13787..15730)
                     /gene="thrS"
                     /locus_tag="VYP85_000919"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1881455.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEDEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15890..16111)
                     /locus_tag="VYP85_000920"
     CDS             complement(15890..16111)
                     /locus_tag="VYP85_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1881456.1"
                     /translation="MELQELVERSWAIRQAYNELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIW"
     gene            16968..17597
                     /locus_tag="VYP85_000921"
     CDS             16968..17597
                     /locus_tag="VYP85_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1881457.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKPLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            17738..18007
                     /gene="rpsO"
                     /locus_tag="VYP85_000922"
     CDS             17738..18007
                     /gene="rpsO"
                     /locus_tag="VYP85_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1881458.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18822..19436
                     /locus_tag="VYP85_000923"
     CDS             18822..19436
                     /locus_tag="VYP85_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1881459.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19729..20478)
                     /locus_tag="VYP85_000924"
     CDS             complement(19729..20478)
                     /locus_tag="VYP85_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1881460.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20611..22947
                     /locus_tag="VYP85_000925"
     CDS             20611..22947
                     /locus_tag="VYP85_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1881461.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23049..23726
                     /locus_tag="VYP85_000926"
     CDS             23049..23726
                     /locus_tag="VYP85_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1881462.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSE"
     gene            23713..24510
                     /locus_tag="VYP85_000927"
     CDS             23713..24510
                     /locus_tag="VYP85_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1881463.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24527..25630
                     /locus_tag="VYP85_000928"
     CDS             24527..25630
                     /locus_tag="VYP85_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1881464.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25637..25783
                     /locus_tag="VYP85_000929"
     CDS             25637..25783
                     /locus_tag="VYP85_000929"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881465.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            25886..26905
                     /gene="galE"
                     /locus_tag="VYP85_000930"
     CDS             25886..26905
                     /gene="galE"
                     /locus_tag="VYP85_000930"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1881466.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKVMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26907..27872
                     /locus_tag="VYP85_000931"
     CDS             26907..27872
                     /locus_tag="VYP85_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1881467.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAAHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(27923..28129)
                     /locus_tag="VYP85_000932"
     CDS             complement(27923..28129)
                     /locus_tag="VYP85_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1881468.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28181..28657
                     /locus_tag="VYP85_000933"
     CDS             28181..28657
                     /locus_tag="VYP85_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1881469.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28666..29337
                     /locus_tag="VYP85_000934"
     CDS             28666..29337
                     /locus_tag="VYP85_000934"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1881470.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29468..29806
                     /locus_tag="VYP85_000935"
     CDS             29468..29806
                     /locus_tag="VYP85_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1881471.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29809..30438
                     /locus_tag="VYP85_000936"
     CDS             29809..30438
                     /locus_tag="VYP85_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1881472.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30678..31829
                     /locus_tag="VYP85_000937"
     CDS             30678..31829
                     /locus_tag="VYP85_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1881473.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32142..32891
                     /gene="truA"
                     /locus_tag="VYP85_000938"
     CDS             32142..32891
                     /gene="truA"
                     /locus_tag="VYP85_000938"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1881474.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFILDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            32881..33654
                     /locus_tag="VYP85_000939"
     CDS             32881..33654
                     /locus_tag="VYP85_000939"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1881475.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33632..34093
                     /locus_tag="VYP85_000940"
     CDS             33632..34093
                     /locus_tag="VYP85_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1881476.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34314..>34423
                     /locus_tag="VYP85_000941"
     CDS             34314..>34423
                     /locus_tag="VYP85_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1881477.1"
                     /translation="MKLSYDDKVQIYELRKQGYSLEKLSNKFGINNSNLR"
BASE COUNT         9936 a         6466 c         7879 g        10142 t
ORIGIN      
        1 ggaaagattt tttataatag ctaaaaaata atagttaaat ggttattaat tgcattccct
       61 agtgattttt gttaagataa aggcaaatac aaatgaaagc gagaacaaga tgacacgtta
      121 tcaagatgat ttttatgatg ctatcaatgg agaatggcaa cagacagctg aaatcccagc
      181 agataagtct caaacaggag gttttgttga tttagaccag gaaattgaag acctgatgct
      241 ggcgacaaca gacaagtggt tagcaggtga agaggtgcct gaggatgcta tcttggaaaa
      301 ctttgtcaaa taccaccgcc tagttcgtga ttttgacaag agagaagctg acggtatcac
      361 acctgtctta ccactcctta aagaattcca agaattggaa acttttgcgg attttacagc
      421 taaactagca gagtttgagc ttgcaggaaa accaaacttc cttccttttg gtgtatcgcc
      481 agactttatg gatgctagaa tcaatgttct atgggctagc gctccaagca caatcttgcc
      541 agatacgacc tactatgcag aagaacatcc tcagcgcgaa gaactcttga ctctttggaa
      601 agaaagcagc gcaaatctcc tcaaggctta tgatttctct gatgaagaaa ttgaagactt
      661 gctagaaaaa agacttgaat tggaccgccg agttgcggca gtggtactct ctaatgaaga
      721 aagttcagaa tatgctaaac tctatcatcc atattcttac gaagatttca agaaattcgc
      781 gcctgcccta cctttggatg acttcttcaa agcagttatt gggcaattac cagacaaggt
      841 tattgtagac gaggaacgtt tctggcaagc agcagagcaa ttctacagtg aggaatcctg
      901 gtctctcctt aaagcaacct tgattttgag tgttgtcaat ctttcaacca gctatttaac
      961 agaggatatc cgtgttttgt ctggtgccta cagccgtgcc ctttctggag ttccagaggc
     1021 aaaagataag gtcaaagcag cttatcatct agcacaagaa cctttcaagc aagccctggg
     1081 gctttggtac gcccgtgaga agttctctcc agaagccaag gcggatgtgg agaaaaaagt
     1141 ggcaaccatg attgatgtct ataaggagcg tctgcttaag aatgactggc tcactccaga
     1201 aacctgtaaa caggctatcg tgaagctcaa tgtgatcaaa ccttatattg gctatccaga
     1261 agaattgcct gcacgttaca aggataaggt agtgaatgaa actgccagtc tttttgagaa
     1321 tgctctagcc tttgcgcgtg tggaaatcaa gcacagttgg agtaagtgga accagcctgt
     1381 agactataag gaatggggca tgcctgctca tatggtcaat gcctactaca atcctcagaa
     1441 gaacctgatt gtctttccag cggccatttt acaggcgcct ttctatgact tgcatcagtc
     1501 atcttctgct aactacggtg gtattggggc agtgattgcc catgaaattt cccacgcctt
     1561 tgatactaac ggggcttcct ttgacgaaaa tggtagcctc aaggattggt ggacagagag
     1621 cgactatgct gccttcaagg agaaaacaca aaaagtcatt gaccaatttg atggacagga
     1681 ttcttatgga gcaaccatta acggtaaatt gactgtatca gaaaacgtgg ctgacttggg
     1741 aggaatcgca gcagcgcttg aagcagctaa gagagaagca gacttctcag cagaagagtt
     1801 cttctacaac ttcggtcgca tctggcgcat gaaaggtcgt ccagaattta tgaaactttt
     1861 ggctagcgtc gatgtgcacg caccagccaa actccgtgtc aatgtgcaag taccaaactt
     1921 cgacgatttc tttacaacct atgatgtcaa agaaggagac ggaatgtggc gttcaccaga
     1981 ggagcgcgtg attatttggt aatacaaaaa atctagtcat cagaaaaaag gcatccaatc
     2041 acgtgtgaaa accttgatag gatgcctttt ataatagaaa gatttgctgg atagtttact
     2101 taaatttcga ttgtcatcat cttgctaaaa aaagggattg aaggcctttt cgtgagcgat
     2161 agtagtagct gaaccatgtc ctggatagac atcgtagttt ggtagggtga agagttgggt
     2221 ctggatacta tgaaggagtt gctccatgct accagtcgga aggtcggtcc gtccgatagt
     2281 ttcgcggaat agagcatctc ccgtcaagac taggtgagca tcaggaaaga ctagggaaac
     2341 accaccgata gagtgccctg gggtcggcag aaccttaaaa tgaaattcct ctagttggta
     2401 ttcttcgtga aagacaaagg tgtgttctgc aggttttgtg accacatctg ccatatcatc
     2461 gtggcgaggg agaccggaga gattatcgac aggagtgtag agccagctgg cttcgctctc
     2521 tgcgatatag acaggaggat tgccaaacgt ctcgcgaacc aagtccagac tcatgatatg
     2581 gtcataatgg gcgtgggtca agagaatagc acagatcggt ttgttgatct tctcgattgt
     2641 ctgacgaatg gcttcccaat gactaccagg atcgacgacg atgaggtact tttcgccttc
     2701 tagataatag gtattttcat aggcaacagg attcacggtt ttatggattt tcatactagc
     2761 tccaatctca aagaatgtac taatactctt cgaaaatctc ttcaaactgc gtcaacttta
     2821 tctgcaacct caaagcagtg ctttgaacag cctgcggcta gctttctagt ttgctctttg
     2881 attttcattg agtataaatt aagtatagca cagttaggga gaataggtaa ggatttaaaa
     2941 tgaacttaaa aaccagcatg actagatgaa gacaggctgg ttatcaattt atcaatattg
     3001 gaaaggtgtc aattgccctt cataggttgc ataaactccg tcattagctt gtttgataga
     3061 cgtgatgttt agagtgctac cgtagttggc ttctcatttg tcgctatatt cactataagt
     3121 tatcctactg ggcaggttct ggtcgttagc atagtattga acgactgttt tttatagctt
     3181 tgctggctga ataggaacag gcagcaaact cctaacatta ggagagcaaa gatagaaata
     3241 gcagtttttt tcataggtat tctccttata aactaaagga tagaagaaag tatcttgagg
     3301 atttttatac tcttcaaaaa tctcttcaaa ccgcgtcaac gtcgccttgc cgtatatatg
     3361 tgactgactt tgtcagtctt atctacaacc tcaaagcagt gctttgagca acctgcggct
     3421 agtttcctag tttgctcttt gattttcatt gagtattaat tccaaaatcc agtcaaggta
     3481 ccagtgtatg tgatacgagt tccaccgttt atctttcgta tcttcaatgg aattggggaa
     3541 atcagaaagt ctttgggtta caatatggtt tccgttcttc tatctctcct tctatcacct
     3601 aagtttaaaa tctaacttcg tagtatatta tgggccaata attcagaatt atcaagcaat
     3661 tttgaattat ttttttctta ttctgttcca atctagtttt catattctta aaaaagtgat
     3721 aaaatggtag gaagaattgg agagtagaga tgccgaaaga agtgaattta acaggcgaag
     3781 aagttgtcgc tttaaccaaa gaatatttaa cggaagagga tgttcatttt gtccataagg
     3841 ccttggtcta tgctgttgaa tgccacagtg gtcaatatcg caaatcaggc gagccttata
     3901 tcattcaccc tatccaagtg gcaggtattt tagctaagct aaagctggat gctgtaacag
     3961 tagcttgtgg attcttgcat gatgtggtgg aagatacaga tgcgaccttg gacgatttgg
     4021 aaagagagtt tggtcctgat gtgcgggtga ttgttgacgg agttaccaag cttggcaagg
     4081 tcgagtacaa atcgatcgag gagcaattag cggaaaatca tcgcaagatg ctcatggcca
     4141 tgtctgagga catccgcgtt attttggtca aactgtctga ccgcttgcac aatatgcgga
     4201 ccctgaaaca tcttcgaaaa gacaagcagg agcgtatttc caaagaaacc atggaaatct
     4261 atgccccact tgcccatcgt ttggggattt ccagtgtcaa atgggaatta gaagacttgt
     4321 ctttccgtta tctcaatcca acggagtttt acaagattac ccatatgatg aaggaaaagc
     4381 gcagggagcg tgaggccttg gtggatgagg tagtcacaaa attagaggag tatacgacag
     4441 aacgtcactt gaaagggaag atttatggtc gtcccaagca tatttactca attttccgca
     4501 aaatgcagga caagagaaaa cggtttgagg aaatctatga tctgattgct attcgttgta
     4561 ttttagatac ccaaagtgat gtttatgcca tgcttggtta cgtgcatgaa ttttggaaac
     4621 cgatgccagg tcgcttcaaa gactatattg ccaaccgcaa ggccaatggt tatcagtcta
     4681 tccatacgac tgtttatgga ccaaaagggc cgattgaatt ccagattcga accaaggaaa
     4741 tgcacgaggt ggctgagtac ggggttgcgg ctcactgggc ttataagaaa ggtataaagg
     4801 ggcaagttaa cagcaaggaa tcagctattg gaatgaactg gatcaaggag atgatggagc
     4861 tccaagacca ggctgatgat gctaaggaat ttgtggactc tgttaaggaa aactatttgg
     4921 ctgaggagat ttacgttttt accccagatg gagctgtccg ttcccttccc aaagattcag
     4981 gaccgattga ttttgcctac gaaatccata ccaaggtcgg tgaaaaagca actggtgcca
     5041 aggtcaatgg ccgcatggtt ccactgacaa ccaagttaaa gacaggggat caggttgaaa
     5101 ttatcgccaa cccgaactcc tttggaccta gccgtgactg gctcaatatg gtcaagacta
     5161 gcaaggcgcg caataagatt cgccagttct ttaaaaacca agataaggaa ttgtctgtca
     5221 acaagggtcg tgagatgctg atggctcagt tccaagaaaa tggctatgtg gcaaataaat
     5281 ttatggacaa gcgccacatg gatcaagttc tgcaaaagac cagttacaag acagaagact
     5341 ccctctttgc ggccattggt tttggggaaa tcggtgcgat taccgtcttt aatcgtctga
     5401 ctgaaaagga acgccgtgag gaagagcgtg ccaaggccaa ggctgaggca gaggagcttg
     5461 tcaaaggtgg cgaggtcaag gttgaaaata aagaaactct caaggtcaag catgaggggg
     5521 gagtggttat tgaaggtgct tctggtctcc tagtgcggat tgctaagtgt tgtaaccccg
     5581 tgcctggtga cgatattgtt ggctacatta ccaagggtcg tggtgtggct attcaccgtg
     5641 tggactgtat gaacctgcgt gcccaagaaa actacgagca acgtctcctt gatgtggaat
     5701 gggaagacca gtactctagc tcaaataagg agtatatggc ccatatcgat atctacggtc
     5761 tcaaccgtac aggactgttg aacgatgtac tgcaagttct ttcaaataca accaagaata
     5821 tttcaacggt caatgcccaa ccaaccaagg atatgaagtt tgctaatatc catgtgtcct
     5881 tcggtattgc caacctctct acactgacca cggttgtcga taaaattaag agtgtgccag
     5941 aagtttactc tgtcaaacgg accaacggct agttgtccta gctcttacta gaaaggctat
     6001 tatgaaaatc attatccaac gggttaaaaa agcccaagtg agtatagaag gccagattca
     6061 gggaaaaatc aatcagggac ttttattgct ggttggtgtt ggaccagagg accaagagga
     6121 agatttggac tatgctgtga gaaaactggt caatatgcgg attttttcag acgcagaagg
     6181 caagatgaac ctgtctgtca aagatattga aggagaaatc ctctctattt ctcagtttac
     6241 cctctttgcg gatactaaga aaggcaatcg tccagccttt acaggggcag ctaaacctga
     6301 tatggcatca gacttctatg atgctttcaa tcaaaaatta gcgcaagaag tgcccgttca
     6361 gacaggtatc tttggagcag atatgcaggt tgagctggtt aataacggac ctgttaccat
     6421 tatcctagat actaaaaaga gataagaaag accaagccca gtcggcttgg tctttctcat
     6481 ctatcataaa atactccaaa aagaaatcgg ttcttgatat gcttggggga agtctctttt
     6541 caggctttgg cagatgcgat aggaagggat gagatgtcct aggatgagga gagttccctg
     6601 aaggaaaagt ggaatatcac ttaaagacac caaggagaga atcatcaggc tatcccatag
     6661 gagaatttgt aaagcaaaac gccagaatct cggtctaatc tgggaataga gttaactaaa
     6721 gtggtcacaa agttggtttg aaagataggt caatagcaca ggatgaaaga aaatgagcca
     6781 accgctataa atcaaaatcc agtcccaagt aagccccctt ttaaatgtca aaaatgccag
     6841 catgattcca tcaatgacaa ggagttgaat ggttttgatg aagatgattt ttttcatgct
     6901 aaaacctcct tttccttaga gacactccca taaagagatg tgtttgtcgt aaaagtctgg
     6961 atagttttct cttaggtagt cagctgtcat ataataaaaa gtagaatggc aagcagtgat
     7021 aattgacata agagatgaaa aacgctgaga actaatgaag gctaagagaa caaaaaatag
     7081 aaaatcaatg gtgagaaccc ctaaatagta gaagcgaatc tttttattga tttgaggata
     7141 aatctcagcg aattgatgtt tgagtcggac gatcaagaga aatagcagga gtccttgagc
     7201 aaggaagaaa attaaaccag agagcaagag ccactcaaaa gatgtctcga gtctaatgat
     7261 aaaaaatgca aatagtagca aatcaataac tgcaattgct ataaaatgga ttctatagag
     7321 ttttttcatg acaagacctc cctcttttat ctaacttcat tctactccaa aagaatggga
     7381 gttacaacta aaatgataaa aatagcagaa gggagattct cttaagttgg ctagtattct
     7441 ttatttgagt ttccttctat tatctaactt cttcatcatt ccagacaaat aaagctccga
     7501 ttgcattgag gatataaaag atgtatttac cgatattggc gaagtttcct tgaataccag
     7561 cttttgtcag ctgaacgaaa ttgtaaatca accaaaagcc ccactgagtt gttagtttta
     7621 atgcattcaa agcattggca atgagggata gtgcaaaggc aatagttgtt acgtaggcaa
     7681 ggagattcat cttgccctca tatccgatat agttggtcac aaaggcaaag aggaaggcga
     7741 tgatggaaat gatgatgacc gccaatttta cctgtttttg gcttatttgg ttgggtctgc
     7801 cttcttgcga agctttccat ttctttatag caaaggtata aatgaggaag gtgacgggat
     7861 aggtaatgat ggccgcctta tttccaagga tataatcaat agcaccggac aaaatggtat
     7921 taacaatacc aaagtaattt ccccatttgc ttaatttccc cgtgaaacga gtggacaaca
     7981 tggaaatccc aacgttggtt acggaaatca atccaaaggg tacaagagct gtccatagtc
     8041 cccagtctac aaatttatcg aggcgtgagt tgagataacc agatgcaatc gcaatcccaa
     8101 cgaccaaagc aaccccgaag aggtcaaacc atttagatgt agcaaaaatt tttagtgatt
     8161 ttttcatagg ttaaactacc tttctttttt tttcaaatat tctaccacca aatgaaagta
     8221 aaataaaatg atagaaataa aaccctgaaa ataaaacttt cagggttggt aggggacttg
     8281 agaaattagt tgattttctc gacatagagt tgttttgcaa tgaccatatt cacttgtaaa
     8341 tcctcgtcgt tactgaggat agtgaaggta ttgctgaagc catcaaactg cttgacttgg
     8401 agctggtcac cgatgtgaag tgagtgcttg tccagataat ggagaatgtc aaaactatcg
     8461 tgcacccgag tcaggcggta ggcgccagct tccttgatat cagctagtgg gaggttattg
     8521 atttcaacga ggagttctcc cttggcagga atagttcctc cgtgggggca ggttttaggg
     8581 aaacctagca gtttatctag tctttccacg aacaggtcag agacagtgtg ttccaagacc
     8641 tcagcttcct cgtgaatctg gtcacttgta tagtctaaat gatgaactag aaaaacttca
     8701 atcaagcggt gcttacgata gagctcagag accagtttga gaccgaggtc agtcagtaga
     8761 tagccacatt ccttgtcctt taggatgaga ttttcacttt tcattcgttt gatcatttca
     8821 gttacggcag ggggagagac ttgcatgcga gccgcaattt ccttgttggt aatcttatgc
     8881 aggtctatgc caatttcata aatacatttt agatagtctt ctttgtttgg ggtcattcgt
     8941 ttcctcttgt ctaatatctt tatctagtat atcaaaaaaa gctagatttc tctagctgtg
     9001 actttttatg ttatacttat tgcaagagaa aaaacgagga gatggatatg acgaaaatag
     9061 ctcttctttc agatattcat ggaaatacca ccgccttgga ggctgttttg gcagatgctc
     9121 ggcagctagg agtggatgaa tactggcttt tgggagatat tctcatgcca gggacaggac
     9181 gtagaaggat tttggacttg ttggatcaac taccgattac ggctagagtt ttgggaaact
     9241 gggaagacag tctttggcat ggtgtccgta aggaattgga tagtactcgc cccagtcaac
     9301 gctatctctt gcgccagtgc cagtatgttt tagaggaaat ttccctagaa gaaattgaag
     9361 tgctccacaa tcaacctctt caacttcatc gtcagtttgg ggatttgacg gtgggaatta
     9421 gccatcatct gcctgataag aactgggggc gagagttgat tcatactggc aaacaagagg
     9481 agtttgaccg cttggtgact catcctccct gtgatattgc tgtttatgga catattcacc
     9541 agcagttgct tcgttacggg actggtgggc aattgattgt caatccgggt tcgattggcc
     9601 aacctttctt tttggacgct cagctacgga aggacttgcg ggcccagtat atgattttgg
     9661 agtttgatga caatggcctg gtagatatgg acttccgacg ggtagactac gatgtggcag
     9721 ctgaattgca gctggctaaa gacctgagac ttccctattt tgaggtttat tatgaaagtc
     9781 tggtcaatgg gatccaccat actcatcatc aggaattttt gagagaattg gctcagaaag
     9841 agggctgcga tcgggagtta gacgactggt tgaaaagtgg taacgattga cattacaact
     9901 aaaaagggta taataataga aaaagaagag tagaggcagg gtagcctcgt aaaaaggaga
     9961 agaggatgca aattccaagt agatttacca ttgcgactca tatgctgata atcattgccc
    10021 tcgaggggaa ggaaagcaag gtgaccagtg attttctggc tgctagtgtc ggggtcaatc
    10081 ctgtcattat cagaaagatc ttgtcccagt tgaagaaggc agagctgatt tcagtagcgc
    10141 gtggaacggg cggaacagag attgtcaagg accttaagga tattagtctt ttagatgttt
    10201 atcaggcggt cgaatgtctt ggtaagacag gtcaactctt cagtttccat gacaatccga
    10261 atcccaattg ccctgtagga gctcatattc atgatgtttt ggatcaaaaa ttggagagaa
    10321 ttcagttgac tatggaggca gaacttggtc agaccagtct agaaaaagtc gtggccgatg
    10381 cagagagtca gatgaaggat taagagggat aaatgccctc tttttttctt tggataatta
    10441 tgataaaatg tagctattaa aggagtaaga aatgtatctt gttataggaa ttgtattagc
    10501 ctttatagtg tcattttgga aggataatag aagtttgtgg aatccagtat tatttttatt
    10561 atccttcatt tcaagttatt tttatctatc ctaccttttt tataaaaatg gatacgagaa
    10621 tgttcagtta gctttttatg tatttgcctt tgtcttactt ccttttttgc tttttctaag
    10681 tggcatcttt ttaatctata atggggtcat tttgttgaaa cgagagggac gttccaagcc
    10741 ccattatctc tcaatgctct ttgattttta ttgactatta gattctattt aaaaagactt
    10801 agaatgcaca tgaaagtatg tattctaggt cttttgtttt gtatacattt aattttcaag
    10861 agtattatct atttttccat gcatggtaac gagtatcaat caataactgg gtaaggcgac
    10921 ccaaggtttc tctttctttt ggagtgaggg attgagcttg gacaaagaga tgatgaatgt
    10981 attcaagcgc ctttaaggaa gccaagtcat tgatagagct aataccagca tcaagaatag
    11041 tgccaaagaa gaggtcgaag tagagctgaa gttcttcgtc agggactgtg gccacccatt
    11101 ctttaaaggt tgtgtctact tgccggctat cactgttggt cttatccagt tgaacgaagt
    11161 gcttgtcctc aatctgccaa ctaaaggtat cgtgctgggc gatgccaccc agggcagtac
    11221 tctgaacgat gatttggtga gcaggaattt ccagcatcat accgataatg gaaccttgtg
    11281 gaatgaatat cttgcttcta tccattatcc tttgataacc cgcagtctgt gtcaattctt
    11341 gatggagacc aggtgcatca aatgtataaa ctgctgtgat ctgattttgc aaactttgct
    11401 caatttggct agcagcatag atagcgagat ttcctccctt ggaatgccca gccagaataa
    11461 ccttttgctt aggatgatgg gcaaaaaagt tctttaaata gcgaagggcg tgcttttgag
    11521 aaggaatttc cttcatatag gtcaggtgga aatcttcctt ccagccaatg atactgtcat
    11581 ctgtcccacg aaagacaatc agataggtat cgaggctgac acgataagtc atagccgcaa
    11641 attgcttttg cagttcaggg tcgatgtcgt tgataaaatg ggagagtttg caatttttga
    11701 agcgcttgtg ttgagccaat tcatctaata attgaaggcg atttttgcta gtaagcatgg
    11761 tgggctctct tggaacctga ggtgctagat ctaaaagacg ttgaggaagt gtggagacca
    11821 gattatcaaa ggagaggtag gtgatttcta ttaaggttag aatgtctaac tcattcaagg
    11881 gaaggtcgta ataagaatca tatgcgacat ctttcagata gtcaaaaata ttggccataa
    11941 gagctccttt ctttttattt atcttagcaa atttccctca aattagctag tagcatagcc
    12001 tgtttgtgct ggctaaaaac aggctatttc aaattcagtt tcagaccatc tagcatggaa
    12061 aaatctgtta taataatgga aaaggagaag cgcatgcaca agattttatt aatagaagat
    12121 gatcaggtca ttcgtcaaca gattgggaaa atgctctctg aatggggatt tgaagtggtc
    12181 ctggtagaag actttatgga agttttgagt ctatttgttc agtcggaacc tcatctggtc
    12241 ctcatggata ttggtttgcc cttgtttaat ggttatcact ggtgtcagga aatccgcaag
    12301 atttccaagg tacctatcat gtttctttct tcgagagacc aggctatgga tattgtcatg
    12361 gcaatcaata tgggggcgga tgactttgtg accaagcctt ttgaccagca ggttctttta
    12421 gctaaggttc agggcttgtt gcgtcgttcc tatgagtttg ggcgtgatga gagtttgctg
    12481 gaatatgctg gtgttatcct caataccaaa tccatggatt tacattatca agggcaagtc
    12541 ttgaatttga ccaagaatga attccagatt ttacgcgtgt tatttgagca tgcaggcaac
    12601 atcgtagcac gtgacgacct gatgcgggaa ctttggaaca gtgacttttt cattgatgat
    12661 aataccctct ctgtcaatgt ggctcgtttg cgtaaaaagt tggaggagca gggattggta
    12721 ggatttatcg agaccaagaa aggaataggg tatggattga agcatgcttg attggaaaca
    12781 attttttcta gcctatctgc gctcccgtag tcgtcttttt atctatctgc tttctttggc
    12841 atttcttgtc ttactctttc agtttttatt tgccagtcta ggaatttact tcctctactt
    12901 tttcttcttg tgttgctttg taaccatatt atttttcact tgggacatat tggtggaaac
    12961 gcaggtctat cgccaggaac ttctctatgg agagagggaa gccaagtctc ctttggaaat
    13021 agctttagca gaaaaattag aagcgcgtga gatggaactc tatcagcaga ggtcaaaagc
    13081 agaaagaaaa ctgacggatt tgctggatta ctataccttg tgggtccatc agataaagac
    13141 ccccattgca gccagtcaac tcttagttgc agaagtggtc gaccgccaac tgaagcagca
    13201 gctagaacag gaaattttca aaatcgactc ctataccaac ctagttttac agtacctgcg
    13261 tttagaaagt ttccatgatg atttggtctt aaagcaggtt caaattgagg acttggtcaa
    13321 ggaaataatt cgtaaatatg ctcttttctt tattcaaaaa ggcttaaatg tcaatctaca
    13381 tgaccttgat aaagaaatcg tgacggataa aaagtggctg ctagtggtta ttgagcaaat
    13441 catctcaaac agtctcaagt acaccaagga aggtggtctg gagatttata tggatgacca
    13501 agagctttgt atcaaagata cgggaatcgg gataaaaaac agtgatgtcc tccgagtatt
    13561 tgaacgtggc ttttcaggat acaatggccg tttgacccag cagtcctctg gacttggcct
    13621 ttatctatct aagaaaattt ctgaagaact ggggcaccag attcgtatcg agtctgaggt
    13681 cggaaaagga acgacagtgc ggattcagtt tgctcaagtg aacttagtcc ttgagtaaaa
    13741 atagatgaga aaaagcctcc agattggagg cttttatgct agactcttat ttctcaacgc
    13801 gtgatttgtt ggcgatatca gctaggatag cttgaacaaa attatcaact gagacagttt
    13861 gtgtttcttt ttggccgtag cgacgaacgt tgactgtttc gtcttccatt tctttgtctc
    13921 caacaattaa ttggtaagga atcttgctag tttgtgaagc acggatcttg aactgcattt
    13981 tttcattgcg ctcatctacg tctgcacgga caccgcggtc acggagtttc ttggctactt
    14041 cccaagcgta gtccacgtgt ttttcgttag atactgggat aagggttact tggtgtggtg
    14101 ccagccatgt tgggaaggca cccttgtagt tctcaatcaa gatagctgtg aagcgttcca
    14161 tagttgagat aaccccacgg tggatcatga ctggacggtg atcttcgcca tcagctccga
    14221 tgtatttgag gtcgaagcgt tctggcaaca agaaatcaag ttggatagta gaaagggttt
    14281 cttcttttcc aagggcagtt ttaatctgga tatccaattt tggtccgtag aaggctgctt
    14341 catcttcggc ttcaaagtag tccacgccca tttcatcaag ggctgcacga agcatggttt
    14401 gggcattttc ccacatctca tcgttatcaa agtacttatg agtatcttga gggtcacgaa
    14461 gagagaggcg gaagcggtag tcagtcaagt tgaagtcttc ataaacatcg ataatcaact
    14521 gaagggcacg ttggaattct tcttggattt gttctggagt aacgaatagg tgaccgtcgt
    14581 tgagtgacat ttcacgtaca cgttgaaggc cagtgagggc accagatttt tcgtaacggt
    14641 gcatcatacc gatttcagcg atacggattg gcaattcacg gtaagagtga acatggtgtt
    14701 tgaaaacttg gatgtggtgc ggacagttca ttggacgaag gacaaattct tccccgtcac
    14761 ccatgtccat ggttgggaac atgtcttctt ggtaatgatc ccagtggcca gaagtcttgt
    14821 aaagctcaac agaagcaagt ggtggagtgt agacgtgttg gtagccagaa gccaactctt
    14881 tgtttacgat gtagcgttcc aattcacgac ggatagtcgc accatttggc aaccagaatg
    14941 gcaaaccttg tcccacttct tgtgaaatca taaagaggtc aagctcttta ccaagtttac
    15001 ggtggtcacg ttccttagct tcttcacgca tttgaaggta gtttttcaag tctttcttgt
    15061 caaaccaagc tgtaccgtag atacgttgca tcatagcgtt gtcgctgttt ccacgccagt
    15121 acgcaccagc tacatggaga aggtggaaga tttggatacg acctgttgat ggaacatgag
    15181 gtccacggca gaggtctaca tattcaccct gacgatagat agtcaaaccg ccttcgtctt
    15241 ctgagtgttc ttcaatcaat tccaacttgt aagggtcatt tttgaagatt tcacgtgcct
    15301 cgtctttagt cacttcttca cgaatagatg ggaagttttc tttgacgatt ttttgcattt
    15361 cttcttcgat acgaggaagg tcttcgttag agatttgacc agctgtgttg tcagtatcgt
    15421 agtagaaacc atcttcgatg gctggaccaa ctcccaagtg aatgtctggg aaaagacgac
    15481 gagctgcttg ggcgaacaag tgagctgctg agtgacgcaa gattggaagg gcatcttcgt
    15541 gatcaggtgt cacaatttcg atgcttccat cttcagtgat agcgcgagta gtgtcgatga
    15601 gtttgccgtt gaatttacca gccaaggctt ttttagctag ggaattgctg atagattggg
    15661 caatttcaaa agttgttacg ccagattcga attcacgaac agcgccatct gggaaagtaa
    15721 tgttaatcat gatgttctcc ttttttatta tttcatagtt tctaagcatt gattttttat
    15781 cagcagacta cttccaagtc ctaacgttca attgcttttc tttatcagag aggaagtttt
    15841 ccatttccgt cagaatgtct atatccaaac gttgagaaag ttctaatagt caccagatat
    15901 tttctgaaag tttttgttcc agtgtgtagg gtgtttcatc atagtagcgt ccttgttttg
    15961 tcatcaccag tcgttggaaa tttccaatat cattagataa agccaagagg tcttcttcta
    16021 ccgtccactt ggaatcatga tgcttaactt ccagttcgtt ataagcttgt cggattgccc
    16081 aactgcgctc cactaattct tgcaactcca taattagtat cctaataaaa aaatgcgaca
    16141 tcctcgaaag gacgtcgcaa cgtggttcca ccttcattta tgtacctcaa aagagaggga
    16201 cacctctgat tggctctaac gtggccaccg ttttatgttt tcataaaaaa ctcaagagta
    16261 gtatcagttt agacttccta tgcgtttcca gcaaccacgc actctctagt agaaagggac
    16321 taagtgactt gtctctatgg attattatag catgattgtg agatttttca aggattttgt
    16381 gaaagttttt tgtttttcat tttttgtaga atatgcttga tgctaatacc agaatccatg
    16441 cccaccagag caactgtttc atagattagc aagtaaatta gtataaactc accaaaggtt
    16501 atgatagtaa agtaaaagag cagtccgtta ccaactaacc atcaaagtga gaaacggaaa
    16561 cggtagctat agagtaacga tacaatcaag attaccagag gtgtaaagaa gagaagattg
    16621 tttatatagt gtaagggggt cagaaacaac tagcaagaac aactcataaa gtggccaata
    16681 aaagaataat atgaccagat agtaggggag atgggaatag aatctacgca tgataatcac
    16741 ctcgttttaa aaaaacagac aacttagatc tcttgctatg attattatag catatttaaa
    16801 acaagaaagt aaatttgttg acaaagaaga ttttttttca ctagaatcat ggttagtttt
    16861 cttggtagaa atattttgat aataattaag caagactatt gacattgatt attaagagtg
    16921 tcacaattgc tgtaactaaa ataattacaa caagagaggt ataaaaaatg aaactagcag
    16981 ttattgcagc aaatggacaa gcggggaaag caattgttga agaagcagtc aaacgaggac
    17041 atgaagtaac ggctattgtt cgttctgaaa acaaaagtca agctgagtct attattaaaa
    17101 aagatttatt tgagttgaca aaagatgatc ttactggatt tgatgctgtt atttcagcgt
    17161 ttggtgctta tacaccagat acgctaccgc tccatagcaa atcaatcgaa ctatttaatc
    17221 agcttcttgc tggaacacag acacgttttc tagttgtagg gggagcagga agcctttata
    17281 tagatgaaac aaaaacgaca cgacttttag atacgcctga ttttcctgaa gaatttaagc
    17341 cactagcaaa agctcaagcg gatgaatttg atcttcttcg tacaaaaaat aatctcaact
    17401 ggacttttgt cagtcctgct gtagatttta ttcccgatgg tgaaaaaaca ggaaactaca
    17461 ttctagcagg agaaattttt actactaatg gaaaaggaat aagccagatt agttatgcag
    17521 attatgctat tggattggta gatgaacttg aaaaaggtca tcatataaaa gaacgtatct
    17581 ctttacttga aaaataataa ctatgagagt attaatgttt gacagaaaat ttaaatcttg
    17641 gtaaaatagg gattgtcgta aagacaaata acttcttctt ggttacaggc atgccaacct
    17701 gtcactcgga tgaagccaaa taaaaaggag aaacatcatg gcaatctcaa aagagaaaaa
    17761 aaatgaaatc attgcacaat atgcacgtca cgaaggtgat acaggttcag tagaggttca
    17821 agttgctgtc cttacttggg aaatcaacca ccttaacgaa cacatcaaac aacacaaaaa
    17881 agaccacgct acttaccgtg gattgatgaa aaaaatcggt cgccgtcgta acttgcttgc
    17941 atacttgcgt aaaaacgacg ttaaccgtta ccgtgagttg atcaactctc taggacttcg
    18001 tcgctaattc aagatacaaa ggccgtcaaa agcacaaagc aaaaatagga aaattgacga
    18061 agaaacttca gtttctagga gattttatct tttttgccaa gtgcttaggc cgtgttcaat
    18121 tgagcatatc ttgataatga agctactcta aattgggtag cttttttgcg ttgtcacctt
    18181 acctcgctat actcaagtat aatctttggt tacggttcct agcactgtaa ggtaaaataa
    18241 accagctttt ctcccttcgg ggagattttt tttgtttcac tgaaagtttc gtacgatctt
    18301 cgcctcgtcg cctagtctat aaacgattta tctagcaaga atcatgatgc taagggcgtc
    18361 aaaaatccgt atgaaaatag ggaaatgaca cagtgttcga tgagcacaag gagtttcatc
    18421 tttttcacta ggattttagc ccgggctcaa atcagctctc tgacttcaga gggctttttt
    18481 attgaggttt tatcggtaac aattttggag actacaaaaa cctcaaacgg tatcagctaa
    18541 ttacaccata aaggtgcgca gttactcggc ttttcaagcc gagtagctgt atgcaagccc
    18601 cctagaagag cccactcttt acaaagtaaa gtatagtatg ttatacttta catggaagta
    18661 gtcactgaat tccagttaga aattactttg taactacgtt ttgaggagga gtaaaatgct
    18721 ttcctacgtt cgacattacc cactagcgat agctaaatta atgtgtctgt gctctcctaa
    18781 aatctgctga tttattactg actaatacag gagttttttt tatgggacag acaatcatat
    18841 ctgctattgg tgtttatatt tccaccagta tcgattattt aattatttta attattttat
    18901 ttgcacagct atcacagaat aaacagaaat ggcatattta tgcggggcaa tatctaggca
    18961 caggcttact tgtaggggcg agtttagttg ctgcttatgt cgttaatttc gtgcctgaag
    19021 aatggatggt tggattgctt ggtttaatcc ctatctattt agggattcgc tttgcaattg
    19081 ttggagaaga tgcggaagaa gaagaggaag aaattattga aagattagaa caaagcaagg
    19141 caaatcaact gttttggaca gttacattgc tgacaattgc gtctggcgga gataatttag
    19201 gtatctatat accttatttt gcttcgttag attggtcaca gaccctcgtg gccttgcttg
    19261 tgtttgtaat cggcataatt atcttttgcg agattagtcg ggtgttatcc tctattccgt
    19321 taatattcga gacaattgaa aaatacgagc gaatcattgt gcccttagta ttcattctac
    19381 ttggactata catcatgtat gaaaatggca cgatagagac ttttctgatc gtgtagattt
    19441 ttttgtttca ctaggatttt agcccgagct caaatcagct ctctgatttt cagagggctt
    19501 tttcattgag tataaatgga caatcttaaa gttactctat tgtagagtgg cttttgattt
    19561 gattaggaga ttcttataaa tatagtaaaa tgaaacaaaa acaggacaaa tcgatcagga
    19621 cagtcaaatc gatttctaaa aatgttttaa gaagtagagg tgtactattc tagtttcaat
    19681 ttgatatata aatgaaaacc ttagctgttt ggccaaggtt catttcttct atgcaagttc
    19741 ttctcttttc ttatctgggt tccagatgaa gcttgcgata aagctaaaga tgatggttag
    19801 gatagcgagg ataatagcaa ggatgagggc agggatgcgg ataaaccacc agagtggatt
    19861 tggtttttta tcattgtgcc attgtttcgt ttcttcgtcc agacgttgga attctgtttg
    19921 aatacgattg gcgactgttt caatgccttc atcattcatt ttcttgatat ctgagatatc
    19981 gattggattt ccaaagttca tatcgacacg ttcacggcta atcaagccct tcaaagtcat
    20041 gggaccggtg taggtaaccg gcatgatacg gaccttggcc attttggcaa tcagtgctgc
    20101 gccccccttg acatcgtttg agtggcggct accacttgga aacatgatga gagagcggtc
    20161 actttttttg agaacgttga taggatattt gatggctgag gcgctgggat tttcacggtc
    20221 gatgggaaag gcgccacaca tacgaatcca ccaaccaaag atacggttgg taaagagttc
    20281 tttttttgcc ataaagatga actgttttgg cttggtcgca aaggccatat aaacaggatc
    20341 ccaccaggta cggtgaggcg caactaaaat ataattttca tcttgattag gaattttatc
    20401 agtattatga tagtgagcat tgccattgat ggaccataag agcaatacaa ctaatccacg
    20461 caaataagta taaaacatgc gatctccttc gattgttttc ttgttattat tataccttat
    20521 caaaggaggg ctggcaaact tttcccttga ctagatgcat atttgggatg aaattagaat
    20581 tctgttaaaa aaaatgatat aatagaattt atggataaaa ataagattat gggattaacc
    20641 caaagagaag tcaaggaaag acaggctgag ggtttggtca atgactttac cgcatcagcc
    20701 agtaccagca cttggcaaat cgttaaacga aatgtcttta ccctttttaa cgctttgaac
    20761 tttgccattg ctttggccct tgcctttgtg caggcttgga gcaatctggt cttctttgct
    20821 gttatctgct ttaacgcttt ttctgggatt gtgaccgagc tacgagccaa acacatggtg
    20881 gacaagctca atctcatgac caaggaaaag gtcaaaacca tccgtgatgg tcaggaagtt
    20941 gctcttaatc ctgaagaatt agtgctagga gatgtcattc gtttgtctgc aggagagcag
    21001 attcctagtg atgccttggt tttggaaggc tttgcggaag tcaatgaagc catgttaacg
    21061 ggagaaagtg atttggtgca aaaggaagtt gacggcttac ttttgtcagg aagtttccta
    21121 gccagtgggt cagttttatc tcaagttcac catgtcggtg cagacaacta tgctgccaaa
    21181 ctcatgcttg aggctaagac cgttaaaccc atcaactccc gtatcatgaa atcgctggac
    21241 aagttggctg gttttactgg gaagattatc attccctttg gtctggctct cttgctggaa
    21301 gccttgcttt taaaaggcct gcctctcaag tcatctgttg taaattcgtc gacagctctt
    21361 ttgggaatgt tgcctaaggg aattgccctt ttgaccatta cttcgctttt gactgcagtg
    21421 attaagctag gtttgaaaaa ggtcttggtg caggagatgt actctgttga gaccttggcg
    21481 cgcgtggata tgctctgtct ggacaagacg ggcaccatca cccaaggaaa gatgcaggtg
    21541 gaggctgttc ttccactgac ggaaacttac ggtgaagagg ctattgccag catcttgact
    21601 agctacatgg cccatagtga ggataaaaat ccaacagctc aagccattcg ccagagattc
    21661 caaggtcaag tagtctatcc tatgctctct aatcttccct tctccagcga ccgcaagtgg
    21721 ggagccatgg agttagaagg tttgggaata gttttcttag gggcacctga gatgttgctg
    21781 gattctgagg tcccagaagc cagagaggcc ttggagagag gttcacgtgt cttggtctta
    21841 gctctcagtc aggagaaatt agaccatcac aaaccacaga aaccatctga tattcaggct
    21901 ctagccttgc tggaaatctt ggatcctatt cgagagggag cggcagagac gctgaactat
    21961 ctccgttctc aggaagtggg gctcaagatt atctctggtg acaatccagt tacggtatcc
    22021 agcattgccc agaaggctgg ttttgcggac tatcacagct atgtcgattg ttcaaaaatc
    22081 acggatgagg aattgattgc tctggcggag gagacagcga ttttcggacg tgtttcccct
    22141 catcaaaaga aactcattat ccaaacgctg aaaaaagcgg gtcatacaac agctatgact
    22201 ggggatggag ttaatgatat cctggctctt cgtgaggcgg attgttctat cgtaatggcg
    22261 gagggagacc cggcaacccg tcagattgcc aacctggttc tcttgaactc agactttaat
    22321 gatgttcctg agattctttt tgaaggtcgt cgtgtggtca ataacattgc ccacatcgct
    22381 ccgattttct tgataaagac catctactca ttcttgctcg cagttatctg tatcgccagt
    22441 gctttactag gtcggtctga atggatcttg attttcccct tcattccaat ccagattacc
    22501 atgattgacc agtttgtgga aggtttccca ccattcgttt tgacttttga gcgaaatatc
    22561 aaacctgtcg agccaaactt cctcagaaga tccatgcttc gtgccctacc aagtgccctc
    22621 atggtcgtgt ttagcgttct ttttgtgaaa atctttggaa cgagtcaagg ttggtctgag
    22681 ttagaaatct caactctcct ctattatctc ttggggtcaa ttggtttctt atccgtattt
    22741 agagcctgca tgccattcac tctatggcga gtcctattga ttgtctggtc agtaggaggc
    22801 ttcctagcca cagctctctt cccaagaatt caaaaactgc ttgaaattgc aaccttaaca
    22861 gaacaaacgt tgcctgttta tggtgtcatg atgttggtct ttacagtgat tttcatcctg
    22921 actagtcgct atcaagctag aaaataaaga aagactgcaa tctgtggatt gcagtttttt
    22981 taggtacaag attgccagcc gaaatgtggt ataataagag gtaatagagt tttggaaagt
    23041 gagagaagat gatttcaaag agattagaat tggtagcttc ctttgtgtca cagggggcta
    23101 ttttactaga tgtgggaagt gaccatgctt atctgcctat cgagttggtt gagagaggcc
    23161 aaatcaaaag cgctattgca ggtgaggtgg tggaaggtcc ctatcagtct gcggttaaaa
    23221 atgttgaggc tcacggccta aaggagaaaa tccaagtccg tttagccaat ggcttggcag
    23281 cttttgaaga gactgaccaa gtgtctgtca ttaccattgc tggcatgggt ggtcgtttga
    23341 ttgctaggat tttagaagaa ggtttgggga agttagctaa tgtagagcgt ttgatcctcc
    23401 agcccaataa tcgtgaagac gacttgcgta tctggctaca ggatcatgga ttccagattg
    23461 tagcagaaag catcttagaa gaagctggca agttttacga gattttggtg gtggaagcag
    23521 gacaaatgaa gctatcagcc agtgatgttc gctttggtcc cttcttgtcc aaagaagtca
    23581 gtccagtatt tgtccaaaaa tggcaaaaag aagctgagaa gctagagttc gccctcggac
    23641 aaatcccaga aaaaaatctg gaagaacgtc aagttctagt agataagatt caagctatca
    23701 aggaggtgcc ccatgttagc gagtgaagtg atccaagctt atgaagcctt ttgccctcag
    23761 gaattttcta tggagggaga cagccgtggt ctgcaaattg gcactttaga caagggtatc
    23821 caaagggtca tggttgccct cgatattcgt gaagagacag tggcagaggc cattgaaaag
    23881 ggtgtggact tgattatcgt caagcacgcg cctatctttc gtcctatcaa ggacttgctt
    23941 gccagccgtc cgcaaaatca gatttacatc gacctgatta agcatgatat cgcagtttat
    24001 gtcagccata ccaatattga tatcgttgaa aatgggctca atgactggtt ttgtcagatg
    24061 ctaggaatcg aggagacgac ttatctgcag gaaacaggtc cagaacgtgg aattggacgt
    24121 attgggaata ttcagcctca gacattttgg gaattggccc aacaggtcaa gcaagtcttt
    24181 gacctagata gccttcgaat ggtgcattat caagagaatg atttgcagaa gcctatttca
    24241 agagtagcaa tttgtggtgg aagcgggcag tctttctata aggatgcttt ggcaaagggg
    24301 gcagatgtct atatcactgg cgacatctac taccatactg ctcaggatat gctgtctgat
    24361 ggcttgttag cattggatcc aggtcactat atcgaagtgc tttttgtgga aaaaatcgca
    24421 gcactcctta ctcaatggaa agagaaaaaa ggctgggaac tagagatttt acctagtcaa
    24481 gcatcgacca atcctttccg tcatatctag ttagaaagtg aagacaatga aaaaagttgc
    24541 cattattgga gcaggaattg tgggagcaac agctgcctac tacctctcga gagaaagtga
    24601 cttagaggtg accgtttttg accatgagca aggtcaagcc accaaggccg cagcaggaat
    24661 tatcagtcct tggttttcca aacgccgtaa taaagcctgg tacaagatgg cgcgcttggg
    24721 ggctgatttt tatgtggatt tattagctga tttagagaaa tcaggacaag aaatcgactt
    24781 ttaccagcgt tcgggagtct ttcttttgaa aaaggatgaa tccaagttgg aagaacttta
    24841 tcaactggcc ctccagcgca gagaagaatc tcccttgata gggcaattag ccattctgga
    24901 ccaagcttca gctaatgaat tattccctgg tttgcaggga tttgaccgcc tgctctatgc
    24961 ttctggtgga gcgagagtag atggccaact cttggtaact cgtttgctag aagccagtca
    25021 tgtcaagctg gtcaaagaaa aagtgactct gacaccgtta gcatcaggct accagattgg
    25081 cgaagaggtg tttgatcagg ttattttggc aacgggagct tggttggggg acatgttaga
    25141 gcctttaggt tatgaagtgg atgtccgtcc tcaaaaagga caactacgag attatcagct
    25201 tgcccaagac atggaagatt accctgttgt catgccagaa ggggagtggg atttgattcc
    25261 ctttgcaggt gggaaattat ccttgggcgc tacccatgaa aatgacatgg gatttgattt
    25321 gacggtagat gaacccttgc tccaacaaat ggaggaggcc accttgactc actatctgat
    25381 tttggctgaa gctacttcaa aatctgagcg tgttggaatc cgtgcctaca ccagtgattt
    25441 ctctcctttc tttgggcagg tgcctgactt aactggtgtc tatgcagcca gtggactagg
    25501 ttcatcaggc ctcacaactg gtcctattat tggttaccat ttagctcaac tgatccaaga
    25561 caaggagttg accttggacc ctgaaaatta cccaattgaa aactatgtca aacgagtaaa
    25621 aagcgaataa tactcaatga aaatcaaaga acaaactagg aaactagccg cgggttactc
    25681 aaagcactgc tttgaggttg tggatagaac tgacgaagtc agtaaccata cccatggcaa
    25741 ggcgacgttg acgtggtttg aattggattt tcgaagagta taagcatttt actgaaattt
    25801 tatcaggtag tttaggatgg caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa
    25861 ataatctgag aatcgaggaa aaaagatgca agaaaagatt ttggtaactg gtggtgccgg
    25921 ttttattgga acccacactg ttattgaatt gatccaagca ggccatcaag ttgttgtggt
    25981 ggataatctt gtcaatagca atcgtaagag tttagaagtt gttgaaagaa tcacaggagt
    26041 tgagattcct ttctatgagg cagatattcg tgacacagat accctcagag atattttcaa
    26101 gcaggaagaa ccgactggtg tcattcactt tgctggtttg aaggctgttg gcgaatcaac
    26161 acgtatccct cttgcctact atgacaacaa tatcgctgga actgtcagcc ttttgaaagt
    26221 catggaagaa aacaactgta aaaacatcat cttcagttct tctgcgacag tttacgggga
    26281 tccgcacaca gtgcccatct tggaagattt cccactttca gtgaccaacc catacggtcg
    26341 tactaagctc atgctagagg aaattttgac tgatatttac aaagcagact cagaatggaa
    26401 tgttgtcttg cttcgttact ttaacccaat cggagcccat gagagtggtg atttgggaga
    26461 aaatccaaac ggtattccaa acaatctctt gccatatgtg actcaagtag ccgttggaaa
    26521 attagagcaa gtgcaagtgt ttggagacga ttacgatacg gaagatggaa caggtgttcg
    26581 tgactatatc cacgttgtcg atttggctaa gggtcacgtt gcagctttga aaaaaatcca
    26641 aaaaggttca ggactaaacg tttataacct tggaactggt aaaggttact cagttcttga
    26701 aattatccaa aacatggaaa aagcggtggg acgtcctatt ccttaccgca tcgtagaacg
    26761 tcgcccaggt gatatcgctg cctgctactc agatccagca aaagctaaag cagaactcgg
    26821 ttgggaagca gaactcgaca tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa
    26881 gcatccaaat ggatttgaag actaagatga tgatttcaat catcgtccct tgtttaaacg
    26941 aagaggaagt acttcctctt ttttatcagg ctctggaagc tttacttcca gatttggaaa
    27001 cagaaatcga gtatgtcttt gtcgatgatg gatcgagtga tgggaccttg gaactcttaa
    27061 aggcctatcg ggagcaaaat ccggcagccc attatatttc tttctcgcga aattttggca
    27121 aagaagcagc cctttatgca ggcttgcaat atgcgacagg agatttggtg gtggtgatgg
    27181 atgcagacct ccaagatcct cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa
    27241 atgtagactt ggactgcgtt gggacacgga gaactagtcg ggagggagaa cccttctttc
    27301 gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc
    27361 cgtcgggtgt ccgtgatttt cgtatgatga gaaggtctgt ggtcgatgcc attttaagct
    27421 tgactgagtc caatcgtttt tcaaaggggc tcttcgcctg ggtgggtttc aaaacctact
    27481 atttggacta tccaaatgtc gaaaggcagg ctggcaagac cagttggagt tttaggcaac
    27541 tctttttcta ctccattgaa gggattatta atttttcaga ttttcccttg attatagcct
    27601 ttgtagctgg tctcctatct tgttttcttt ctctgctgat gacctttttt gttgtggttc
    27661 ggaccctcat tttgggcaat ccgacatctg gttggacctc tctgatggct gttattctct
    27721 ttcttggagg cattcaactc ttgaccattg ggattctcgg aaagtatatc agtaagattt
    27781 atttagagac taaaaaaaga ccactttatc ttatcaaaga aaaaagtgac cttcctgatt
    27841 ttacagaaaa aaataaagtg aaaagactat aattttacat ggaaatatgc taaactagag
    27901 ggagtggatt atcgccattg atttaggctt cctggtttcc aatcagggcg cgagttgggc
    27961 aatttttaac agcctctaag acatcctgac taggagaaat ttctttttcc agttggtcag
    28021 ggtcatcgta aaaacgcacg attccattat cgtggtaatc aaataaatca gaataagttt
    28081 ggcaaagccc acaggcgata catcgttcag gtataagtgt gattttcatg ttcatattta
    28141 tattgtaata agaaaagtaa aaaaaaacaa ggagtaaggt atggcaaaag aaccgtggca
    28201 agaagatatc tatgatcaag aagaatcaag agcagagcgt cggcatcgaa accacggagg
    28261 ggctgatagg atggctaatc gtattttgac gatcctagct agtattttct ttgtaattgt
    28321 ggtggtgatg gtcatcgttc tcatctatct atcatcgggg gggagtaatc gcacagcagc
    28381 cttaaaagac tttcatgatt ctgatgcaag tgtagtacaa atctcatctt caagcagttc
    28441 tcagcctgag cagagttcag agccagaatc tacttctagt agttcagaag aagctgctaa
    28501 tcctgaagga acgattaaag ttctcgcagg agaaggggaa gcagctattg ccgctcgtgc
    28561 aggaatctcc attgctcagt tagaggcctt gaatcctggg cacatggcta caggatcttg
    28621 gtttgctaat ccaggtgatg ttataaaaat aaaataggag ccgatatgaa aacaattcaa
    28681 attgctattg atggtcctgc ttccagcggt aagagtacgg tcgcaaagat tattgctaag
    28741 gattttggat tcacctacct tgatacagga gctatgtatc gtgcagcgac ctatatggct
    28801 cttaagaacc aattaggagt tgaagaagtc gaagcccttc tagccttgtt ggaccagcat
    28861 ccaatcagct ttggacgttc agaaactgga gaccagcttg tttttgtagg agatgtggat
    28921 attacccatc ctatccgtga aaatgaagtg accaatcatg tttctgctat tgcagcaatt
    28981 cctgaagtgc gtgagaaact ggtttctctc caacaagaaa ttgcccagca aggcgggatt
    29041 gtcatggatg gtcgcgatat tggaactgtt gtattgccac aagcagaatt gaaaattttc
    29101 ctagtagctt ctgttgatga gagagcagag cgtcgttaca aggaaaatat tgccaaggga
    29161 attgaaacag accttgaaac cctaaaaaag gaaattgctg cgcgtgacta caaggatagt
    29221 catcgtgaga cttctcctct caaacaagca gaggatgctg tctaccttga tacaactggt
    29281 ttgaacattc aagaagtagt tgaaaaaatc aaagcagaag ctgaaaaaag aatgtaaatg
    29341 tagaaaagcc gatagattga tatcggtttt tttctaaatt tgtcaaaatg ctgattttag
    29401 ggtataatag ttgctgttcg agaaattttg attttcaaag aatagtgaat gatgataagg
    29461 agaaaccatg aacaatttac caaattgtcc aaaatgtaac tcagagtatg tctacgaaga
    29521 cggtgcccta ctggtttgcc cagagtgtgc tcatgagtgg aatcctgctg aagttgcaga
    29581 agtagaagaa ggtcttgtcg ctatcgatgc caacggaaat aaattgactg atggtgatac
    29641 agtaactctc atcaaggact tgaaagtaaa aggtgcgcca aaagatttga aacaagggac
    29701 gcgcgtgaaa aatatccgca tcgtagaagg cgaccacaat atcgactgta agattgatgg
    29761 ttttggtgcc atgaaactta aatcagagtt tgtgaggaag atttaagcat gtcaaaacac
    29821 tataaacttg tattttatag ccgtatcttc ttgtttctag cggcttttac gggagtttat
    29881 cttgaaatta ctaggcatgg tggttttggg atgcttctct attacacggt tctgtccaac
    29941 ctcttggtaa ctatttttac cctttatctt ctaaaggtta tgagccgtgt aggtgaaaat
    30001 tggcaaaggc caagtctctt gcgcttaaaa ggtggggtca ccatgagtat catgattacc
    30061 tgtgtgattt accatttcct cttggcgccc attgcgacta atttctatac cctagaaaat
    30121 ttcctttgcc actatatcgt tcccatctgg tttttagcgg ataccctctt ttttgacaaa
    30181 cagggtcaat acaagatttg ggatccagca gtgtggacca ttttaccctt tctgtatatg
    30241 atgtttgctc tttttaatgg cttggttcta aaactcaata ttccaaatgc caaggataat
    30301 cctttccctt acttcttttt gaatgtgaac aagggttgga atgttgtgtt taagtggtgt
    30361 ctgattatct ttgttgccta tatggtagca ggatttattt tctactttat caagcaaatc
    30421 aagagaaagt catcctaata ctcttcgaaa atctcttcaa accacgtcag tttccatctg
    30481 caacctcaaa acactgtttt gaacaacctg cggctagctt cctagtttgc tctttgattt
    30541 tcattgagta taagatacaa gggattcatt ttcgaattta agaaggagtc tacaaaccaa
    30601 tgaggcttct tcttttcttg cttatttgat aactatcaaa aaagtagaag attaagagaa
    30661 atatagaaag agatttcatg aaacaatttt tagaacgggc cagcattttg gctctctccc
    30721 tcgttttgat tacctccttt tccatttcga gtgctctacc agccatgttt gactattatc
    30781 agggttattc taaggaacaa attgagctct tggtgagctt gccttccttt ggaatcatga
    30841 tgatgttact gctaaatggt ttcttagaaa aaatatttcc tgagcgctta cagattagtt
    30901 tgggcttgct gattttatca ttgagcggta cagctccctt ctggtaccaa gcctatccct
    30961 ttgtctttgg aacacggctt ctctttggtt tgggtcttgg gatgatcaat gccaaggcca
    31021 tttctattat cagtgaacgc taccaaggaa aaaggcgaat tcagatgtta gggctacgcg
    31081 cttctgcaga ggtcgttgga gcttctctca ttaccttggc cgtcggtcag ttgttggcct
    31141 ttggttggac agctatcttt ctagcctata gtgctggatt tttggtgctg cccctttatc
    31201 tgctctttgt cccttatgga aaatcaaaga aagaagtcaa gaaaagagcg aaggaagcaa
    31261 gtcgtttaac tcgagaaatg aaaggcttga tttttacctt agctatcgaa gcggcagttg
    31321 tagtttgtac caatacagct attaccatcc gtattccaag tttgatggtg gaaagaggat
    31381 tgggggatgc ccagttatct agttttgttc ttagtatcat gcagttgatc gggattgtgg
    31441 ctggggtgag tttttctttc ttgatttcta tctttaaaga gaaactgctc ctctggtctg
    31501 gtattacctt tggcttgggg caaattgtga ttgccttgtc ttcatccttg tgggtggtag
    31561 tagcaggaag tgttctggct ggatttgcct atagtgtagt cttgacgacg gtctttcaac
    31621 ttgtctctga acgaattcca gctaaactcc tcaatcaagc aacttcattt gctgtattag
    31681 gctgtagttt cggagccttt acgaccccat ttgttctagg tgcaattggc ttactaactc
    31741 acaatgggat gttggtcttt agtatcttag gaggttggtt gattgtaatc tctatctttg
    31801 tcatgtacct acttcagaag agagcttagg attgattcct aagtttttct tttgatactc
    31861 aatgaaaatc aaagagcata gttgattgag tttggaatag tacgctgtag ttgctaaaat
    31921 atttctagaa attaatttga cttttctaat agagttattc atatcttatt tcaatctact
    31981 atagaaagct agccgcaggt tgctcaaaat agtgttttga ggttgcagat ggaaactgac
    32041 gtggtttgaa gagattttcg aagagtatga gatttttata cccatacaat atttgtttta
    32101 ggtccttgtt tacagactaa tttcttgata aaatagaggt tatgacgaga tataaagcaa
    32161 ctatttccta tgatggttat gcctttgctg gctttcagcg ccagtctcat gcgcgtagcg
    32221 ttcaggaaga aattgaaaaa accttgacca gattaaataa agggcaaacc attactgttc
    32281 acggtgctgg taggacagat agtggggttc atgccctggg acaggtcatt cattttgacc
    32341 tgccttatca gatggatgag gagaaactcc gttttgcctt ggatacccag tctcctgaag
    32401 atattgatgt gatttcgatt gagcttgtgg cagatgattt tcattgccgt tatgccaaac
    32461 atagcaagac ctatgagttt attttggata gaggacgtcc caaaaatcct atgcgccgtc
    32521 actatgccac ccactttccc tacccactcg atgtggaacg aatgcagatt gcaatcaaaa
    32581 agctagaggg aacccatgat tttaccggtt ttacagcctc tgggactagt gtagaggata
    32641 aggttcgcac catcacagaa gctagtttaa tagtcgatga gacaggacaa tttttgacct
    32701 ttaccttttc aggaaatggt ttcttgtata aacagattcg caatatggtg gggactcttc
    32761 tcaaaatcgg taacaaccgc atgccagtag agcagattga tctcatcttg gagaagaagg
    32821 acaggcaact tgcaggtccc actgcagcac caaatggttt gtatttaaag gagattcgtt
    32881 atgaagaata atcgtatttt agcactttct ggaaatgata tttttagtgg tggtggactg
    32941 tcagctgatt tggctaccta taccttgaac ggcttgcatg ggtttgtagc agtgacttgt
    33001 ttgacagcct tgacagaaaa aggatttgaa gtctttccaa ctgatgatac catttttcaa
    33061 catgaattag atagcttgcg tgatgtggaa tttgggggaa ttaagattgg tcttctccct
    33121 actgtcagtg tggctgagaa ggccttggac tttatcaaac aacgcccagg agtacctgtg
    33181 gtgttggatc ctgtcttggt ctgcaaggaa acgcatgatg tagctgtcag tgagctctgc
    33241 caagagttga ttcgcttttt cccttatgtc agtgtgatta cgcctaatct cccagaagca
    33301 gaattattat ccggtcagga aattaaaacc ttggaagaca tgaaaactgc agcgcagaaa
    33361 ttgcatgatt taggagcgcc agcagtcatt atcaagggag gcaatcgtct tagtcaggac
    33421 aaggctgtgg atgtctttta tgatggacag acctttacta tcctagaaaa tccagttatc
    33481 caaggccaaa atgctggtgc aggttgtacc tttgcctcta gcattgccag tcacttgatt
    33541 aaaggtgata aacttttgcc agcagtagaa agctctaagg ctttcgttta tcgtgctatt
    33601 gcacaagcag atcagtatgg agtaagacaa tatgaagcaa acaaaaacaa ctaaaatcgc
    33661 ccttgtatcc ctattaaccg ccctttctgt ggttctaggt tatttcttaa aaatcccaac
    33721 acctacagga attctaactc ttttagatgc tggtgtcttc tttgcggcct tttactttgg
    33781 tagtcgtgaa ggagcggtag tcggaggact agcaagtttc ttgattgacc tcttatcagg
    33841 ctaccctcag tggatgttct ttagcttggt caaccatggc ttgcagggat ttttcgcagg
    33901 atttaaagga aaaagtcagt ggttaggcct tattttagca actattgcca tggtaggagg
    33961 ctacgccttg ggttctactt tgatgaatgg ctgggcagca gccctcccag aaattctacc
    34021 aaatttcatg caaaatatgg tagggatgat tgtaggattt attcttagtc aaagtatcaa
    34081 gaagattaag taatactctt cgaaaatctc ttcaaaccac gtcagcttcc atctgcaacc
    34141 tcaaaccact gttttgagca gcctgaggct agctttctag tctgattttc attgagtata
    34201 aagaggttga gtaaaaagta tttcaaataa gaaaaacgca tagtatcagg tgttgaatga
    34261 actgcccccc aaaagttaga cagaaaaaat ctaacttttg gggtgttttt attatgaaat
    34321 taagttatga tgataaagtt cagatctatg aacttagaaa acaaggatat agcttagaga
    34381 agctttcaaa taaatttggg ataaacaatt ctaatcttag gta
//
LOCUS       DAVMCN010000016        34372 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVMCN010000016 DAVMCN010000000
VERSION     DAVMCN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.016"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            479..931
                     /locus_tag="VYP85_000942"
     CDS             479..931
                     /locus_tag="VYP85_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1881478.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            950..2287
                     /locus_tag="VYP85_000943"
     CDS             950..2287
                     /locus_tag="VYP85_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1881479.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2366..3250
                     /locus_tag="VYP85_000944"
     CDS             2366..3250
                     /locus_tag="VYP85_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1881480.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3250..4083
                     /locus_tag="VYP85_000945"
     CDS             3250..4083
                     /locus_tag="VYP85_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1881481.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4101..6194
                     /gene="nanB"
                     /locus_tag="VYP85_000946"
     CDS             4101..6194
                     /gene="nanB"
                     /locus_tag="VYP85_000946"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1881482.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6206..7309
                     /locus_tag="VYP85_000947"
     CDS             6206..7309
                     /locus_tag="VYP85_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1881483.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7483..8181
                     /locus_tag="VYP85_000948"
     CDS             7483..8181
                     /locus_tag="VYP85_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1881484.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8200..9717
                     /locus_tag="VYP85_000949"
     CDS             8200..9717
                     /locus_tag="VYP85_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1881485.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9842..11170
                     /locus_tag="VYP85_000950"
     CDS             9842..11170
                     /locus_tag="VYP85_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1881486.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11422..12288
                     /locus_tag="VYP85_000951"
     CDS             11422..12288
                     /locus_tag="VYP85_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1881487.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12304..13143
                     /locus_tag="VYP85_000952"
     CDS             12304..13143
                     /locus_tag="VYP85_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1881488.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13415..13867
                     /locus_tag="VYP85_000953"
     CDS             13415..13867
                     /locus_tag="VYP85_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1881489.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            13964..14308
                     /locus_tag="VYP85_000954"
     CDS             13964..14308
                     /locus_tag="VYP85_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881490.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGTY
                     AAKYGISMARSILSRVAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14585..15229
                     /locus_tag="VYP85_000955"
     CDS             14585..15229
                     /locus_tag="VYP85_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1881491.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15398..16315
                     /locus_tag="VYP85_000956"
     CDS             15398..16315
                     /locus_tag="VYP85_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1881492.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEVLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16333..17217
                     /locus_tag="VYP85_000957"
     CDS             16333..17217
                     /locus_tag="VYP85_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1881493.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17233..18084)
                     /locus_tag="VYP85_000958"
     CDS             complement(17233..18084)
                     /locus_tag="VYP85_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1881494.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18284..20341
                     /gene="pbp2b"
                     /locus_tag="VYP85_000959"
     CDS             18284..20341
                     /gene="pbp2b"
                     /locus_tag="VYP85_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1881495.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20352..20948
                     /gene="recR"
                     /locus_tag="VYP85_000960"
     CDS             20352..20948
                     /gene="recR"
                     /locus_tag="VYP85_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1881496.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21124..22167
                     /locus_tag="VYP85_000961"
     CDS             21124..22167
                     /locus_tag="VYP85_000961"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1881497.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNNITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            22251..23624
                     /locus_tag="VYP85_000962"
     CDS             22251..23624
                     /locus_tag="VYP85_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1881498.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LVQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23611..24222
                     /locus_tag="VYP85_000963"
     CDS             23611..24222
                     /locus_tag="VYP85_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1881499.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24313..25017
                     /locus_tag="VYP85_000964"
     CDS             24313..25017
                     /locus_tag="VYP85_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1881500.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25236..26609
                     /gene="ftsA"
                     /locus_tag="VYP85_000965"
     CDS             25236..26609
                     /gene="ftsA"
                     /locus_tag="VYP85_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1881501.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26626..27885
                     /gene="ftsZ"
                     /locus_tag="VYP85_000966"
     CDS             26626..27885
                     /gene="ftsZ"
                     /locus_tag="VYP85_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1881502.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27890..28561
                     /locus_tag="VYP85_000967"
     CDS             27890..28561
                     /locus_tag="VYP85_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1881503.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28571..29110
                     /locus_tag="VYP85_000968"
     CDS             28571..29110
                     /locus_tag="VYP85_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1881504.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29110..29373
                     /locus_tag="VYP85_000969"
     CDS             29110..29373
                     /locus_tag="VYP85_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1881505.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29370..30167
                     /locus_tag="VYP85_000970"
     CDS             29370..30167
                     /locus_tag="VYP85_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1881506.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFLTPFIN
                     PHQEKLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNK
                     FEHLTHAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPV
                     SLEERPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYH
                     VVDKSDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30176..30964
                     /gene="divIVA"
                     /locus_tag="VYP85_000971"
     CDS             30176..30964
                     /gene="divIVA"
                     /locus_tag="VYP85_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1881507.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31312..34104
                     /locus_tag="VYP85_000972"
     CDS             31312..34104
                     /locus_tag="VYP85_000972"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1881508.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10561 a         6064 c         7468 g        10279 t
ORIGIN      
        1 tagccaaaga gtctattagt gctagaataa tagattagaa ttattttaga aaaacgaagt
       61 gagcagctta taaattcaag tccccaaata gattcatact agtatctttt gcaaaaaata
      121 aagggcgact tccttcatga atatcaattt catctataag gaaggtagct aattgaacta
      181 acttatttat tctgtttgtc gctagaaaaa tcagacctcc ttgtgaagat tgaggagata
      241 cttaatgaaa atcaaagaag aaactagcaa gctagtagca gattgcccaa aacaccgctt
      301 tgaggttgta gataagactg acctatataa tccaaggtga agcgactgtg gtttgaagag
      361 attttcaaag agtataggct agagagtagt gtttttatgt ccttctagta gaaaatgcta
      421 gacagaagaa tggggaactt ggataggaaa aatagattga gaaaggaggt tagaagagat
      481 gattattaca aaaattagcc gtttaggaac ttatgtggga gtaaatccac attttgcaac
      541 attaatagat tttctagaaa aaacaggact agaaaattta acagaaggtt cgattgctat
      601 cgatggtaat cgattgtttg ggaattgctt tacttatcta gcagatggtc aagcaggggc
      661 tttctttgaa acccaccaaa aatatttgga tattcattta gttttggaaa acgaagaagc
      721 catggctgtt acatcgccgg aaaatgtaag cgttacccaa gaatatgatg aagagaaaga
      781 tattgaatta tacacaggga aagtggaaca gttggttcat ttgagagctg gcgaatgcct
      841 catcactttt ccagaagatt tacatcaacc caaggttcgt ataaatgatg aacctgtgaa
      901 aaaagttgtc tttaaagttg cgatttctta atgtagaaag agaagaacga tgaaaaaaat
      961 gagaaagttt ttatgtctag ctggaattgc gctagcggct gttgccttgg tagcttgttc
     1021 aggaaaaaaa gaagctacaa ctagtactga accaccaaca gaattatctg gtgagattac
     1081 aatgtggcac tcctttactc aaggaccccg tttagaaagt attcaaaaat cagcagatgc
     1141 tttcatgcaa aagcatccaa aaacgaaaat caagattgaa acattttctt ggaatgactt
     1201 ctatactaaa tggactacag gtttagcaaa tggaaatgtg ccagatatca gtacagctct
     1261 tcctaaccaa gtaatggaaa tggtcaactc agatgctttg gttccgctaa atgattctat
     1321 caagcgtatt ggacaagata aatttaacga aactgcctta aatgaagcaa aaatcggaga
     1381 tgattactac tctgttcctc tttattcaca tgcacaagtc atgtgggtta gaacagattt
     1441 gttaaaagaa cataatattg aggttcctaa aacttgggat caactctatg aagcttctaa
     1501 aaaattgaaa gaagctggag tttatggctt gtctgttccg tttggaacaa atgacttaat
     1561 ggcaacacgt ttcttgaact tctacgtacg tagtggtgga ggaagcctct taacaaaaga
     1621 tcttaaagca gacttgacaa gccaacttgc tcaagatggt attaaatact gggttaaatt
     1681 gtataaagaa atctcacctc aagattcttt gaactttaat gtccttcaac aagctacctt
     1741 gttctatcaa ggaaaaacag catttgactt taactctggc ttccatatcg gaggaattaa
     1801 tgccaacagt cctcaattga ttgattcgat tgatgcttat cctattccaa aaatcaaaga
     1861 gtctgataaa gaccaaggaa ttgaaacctc aaacattcca atggttgttt ggaaaaattc
     1921 aaaacatcca gaagttgcta aagcattctt agaagcactt tataatgaag aagactacgt
     1981 taaattcctt gattcaactc cagtaggtat gttgccaact attaagggga ttagcgattc
     2041 tgcagcctat aaagaaaatg aaactcgtaa gaaatttaaa catgctgaag aagtaattac
     2101 tgaagctgtt aaaaaaggta ctgctattgg ttatgaaaat gggccaagtg tacaagctgg
     2161 tatgttgact aaccaacaca ttattgaaca aatgttccaa gatatcatta caaatggaac
     2221 agatcctatg aaagcagcaa aagaagcaga aaaacaatta aatgatttat ttgaggctgt
     2281 tcagtagatg taaaagacta gaaaataggt gggatagtga gctgaaaagc tctagcccaa
     2341 tcttgtaaaa gaagggagaa ggagaatggt taaagaacgt aatttaactc gctggatatt
     2401 tgttttgcca gctatgatta tcgtaggatt actctttgtt tatccgtttt tctcgagtat
     2461 tttttatagc tttaccaata agcatttgat tatgcctaat tataaatttg ttggtttggc
     2521 taactataaa gctgtgctat cagatcccaa cttctttaat gcgttcttta attcaattaa
     2581 gtggaccgtt ttctcattag ttggtcaagt tttagtaggg tttgtattgg ctttagctct
     2641 tcacagagta cgccacttca agaaattata taggacatta ttgattgttc cttgggcatt
     2701 tcctaccatc gttattgcct tctcttggca gtggattcta aacggggttt atggctactt
     2761 acctaatcta atcgtaaaat taggtttaat ggaacataca cctgcatttt tgacagatag
     2821 tacatgggca ttcctatgtt tggtgtttat caacatttgg tttggagcac caatgattat
     2881 ggttaatgtg ctttcagctt tgcaaacagt accagaagaa caatttgagg ctgctaagat
     2941 agatggtgct tcaagttggc aggtgttcaa gtttatcgtc tttccacata ttaaagtggt
     3001 tgtaggactt ctagttgttt tgagaactgt atggatcttt aataactttg acattatcta
     3061 cctcattact ggtggtggac cagccaatgc tacaacgacg cttccaattt ttgcttacaa
     3121 cctgggctgg ggaactaaat tgttgggtcg tgcttcagca gttacagtac tgctctttat
     3181 cttcttggtg gcgatttgct ttatctactt tgctatcatc agtaagtggg aaaaggaggg
     3241 tagaaaataa tgaagaagaa atccagtatt tatttagata ttctctcaca tgtactttta
     3301 gttggtgcga ccatcgttgc agttttccca ttggtatgga ttatcatatc ttctgtcaaa
     3361 gggaaagggg aattaactca gtatccaaca cgattttggc ctgaacagtt tacattagat
     3421 tatttcactc atgttatcaa cgatttgcac ttcattgata acattcgaaa cagtttaatc
     3481 attgccttgg ctacaaccct tattgcgatt attatttctg ctatggcagc ctatggtatt
     3541 gttcgattct ttcctaaatt gggagcaatc atgtcgagac tactcgtcat tacctacatt
     3601 ttcccaccaa ttttgttagc aattccctat tcaattgcca ttgctaaagt tgggttaaca
     3661 aatagtttat ttggcttgat gatggtttat ctatctttta gtgttccata tgcagtttgg
     3721 ctcttagttg gatttttcca aacagttcca attggaattg aagaagcggc tagaattgat
     3781 ggtgcaaata aatttgttac gttttataaa gttgtgctac cgattgtagc accaggtatt
     3841 gtagcaacag ctatttatac atttatcaat gcttggaatg aattcctgta tgccttgatt
     3901 ttgattaaca atacaggaaa gatgacagta gcagtagccc ttcgttcact taatggttca
     3961 gaaatactag actggggaga tatgatggca gcgtctgtta ttgtagttct tccatcaatt
     4021 attttcttct ctatcatcca aaataagatt gcaagtggat tatcagaagg atctgtgaag
     4081 tagacgaaag aaggaaaaaa atgaataaaa gaggtcttta ttcaaaacta ggaatttccg
     4141 ttgtaggcat tagtctttta atgggagtcc ccactttgat tcatgcgaat gaattaaact
     4201 atggtcaact gtccatatct cctatttttc aaggaggttc atatcaactg aacaataaga
     4261 gtatagatat cagctctttg ttattagata aattgtctgg agagagtcag acagtagtaa
     4321 tgaaatttaa agcagataaa ccaaactctc ttcaagcttt gtttggccta tctaatagta
     4381 aagcaggctt taaaaataat tacttttcaa ttttcatgag agattctggt gagataggtg
     4441 tagaaataag agacgcccaa aagggaataa attatttatt ttccagacca gcttcattat
     4501 ggggaaaaca taaaggacag gcagttgaaa atacactagt atttgtatct gattctaaag
     4561 ataaaacata cacaatgtat gttaatggaa tagaagtgtt ctctgaaaca gttgatacat
     4621 ttttgccaat ttcaaatata aatggtatag ataaggcaac actaggagct gttaatcgtg
     4681 aaggtaagga acattacctc gcaaaaggaa gtattgatga aatcagtcta tttaacaaag
     4741 caattagtga tcaggaagtt tcaactattc ccttgtcaaa tccatttcag ttaattttcc
     4801 aatcaggaga ttctactcaa gctaactatt ttagaatacc gacactatat acattaagta
     4861 gtggaagagt tctatcaagt attgatgcac gttatggtgg gactcatgat tctaaaagta
     4921 agattaatat tgccacttct tatagtgatg ataatgggaa aacgtggagt gagccaattt
     4981 ttgctatgaa gtttaatgac tatgaggagc agttagttta ctggccacga gataataaat
     5041 taaagaatag tcaaattagt ggaagtgctt cattcataga ttcatccatt gttgaagata
     5101 aaaaatctgg gaaaacgata ttactagctg atgttatgcc tgcgggtatt ggaaataata
     5161 atgcaaataa agccgactca ggttttaaag aaataaatgg tcattattat ttaaaactaa
     5221 agaagaatgg agataacgat ttccgttata cagttagaga aaatggtgtc gtttataatg
     5281 aaacaactaa taaacctaca aattatacta taaatgataa gtatgaagtt ttggagggag
     5341 gaaagtcttt aacagtcgaa caatattcgg ttgattttga tagtggctct ttaagagaaa
     5401 ggcataatgg aaaacaggtt cctatgaatg ttttctacaa agattcgtta tttaaagtga
     5461 ctcctactaa ttatatagca atgacaacta gtcagaatag aggagagagt tgggaacaat
     5521 ttaagttgtt gcctccgttc ttaggagaaa aacataatgg aacttactta tgtcccggac
     5581 aaggtttagc attaaaatca agtaacagat tgatttttgc aacatatact agtggagaac
     5641 taacctatct catttctgat gatagtggtc aaacatggaa gaaatcctca gcttcaattc
     5701 cgtttaaaaa tgcaacagca gaagcacaaa tggttgaact gagagatggt gtgattagaa
     5761 cattctttag aaccactaca ggtaagatag cttatatgac tagtagagat tctggagaaa
     5821 catggtcgaa agtttcgtat attgatggaa tccaacaaac ttcatatggc acacaagtat
     5881 ctgcaattaa atactctcaa ttaattgatg gaaaagaagc agtcattttg agtacaccaa
     5941 attctagaag tggccgcaag ggaggccaat tagttgtcgg tttagtcaat aaagaagatg
     6001 atagtattga ttggaaatac cactatgata ttgatttgcc ttcgtatggt tatgcctatt
     6061 ctgcgattac agaattgcca aatcatcaca taggtgtact gtttgaaaaa tatgattcgt
     6121 ggtcgagaaa tgaattgcat ttaagcaatg tagttcagta tatagatttg gaaattaatg
     6181 atttaacaaa ataaaggaga aaaacatggt taaatacggt gttgttggaa cagggtattt
     6241 tggagctgaa ttggctcgct acatgcaaaa gaatgatgga gcagagatta ctcttctcta
     6301 tgatccagat aatgcagagg cgattgcaga agaattggga gcaaaagtag caagttcctt
     6361 agatgagttg gtttctagcg atgaagtaga ttgtgttatc gtcgcaactc caaataatct
     6421 tcataaggaa ccggttatta aggctgcaca gcatggtaaa aatgttttct gtgaaaaacc
     6481 aattgcgctt tcttatcaag attgtcgcga gatggtagat gcgtgtaaag aaaacaatgt
     6541 aacctttatg gcaggacata ttatgaattt ctttaatggt gttcatcatg caaaagaact
     6601 cattaatcaa ggagttatcg gagacgttct atattgtcat acagctcgta atggttggga
     6661 agaacaacaa ccgtcagtat catggaaaaa aattcgtgaa aaatcaggtg gtcacttgta
     6721 tcaccacatc catgaattgg attgcgttca attccttatg gggggcatgc ctgaaactgt
     6781 aaccatgaca ggtggaaatg tggcccatga aggtgaacat ttcggtgatg aagatgatat
     6841 gatttttgtc aatatggaat tttctaataa gcgttttgcc ttgttagaat ggggttcagc
     6901 ttatcgttgg ggtgaacatt atgtcttaat ccaaggaagc aaaggtgcca tccgcttaga
     6961 cttattcaac tgtaaaggaa ctcttaagct agatgggcaa gaaagctatt tcttgattca
     7021 cgaatcgcaa gaagaagatg atgatcggac tcgtatctat catagtacag agatggatgg
     7081 agcaattgct tatggtaaac caggtaaacg tactccatta tggctatcat ctgtcattga
     7141 taaagaaatg cgctatctgc atgagattat ggaaggagct ccagtatcag aagaatttgc
     7201 aaaacttttg acaggtgaag ctgccctaga agcaattgct actgcagatg cttgtaccca
     7261 gtctatgttt gaagatcgca aagtaaaatt gtcagaaatt gtaaaataaa ttttggtatt
     7321 ctcctattta taggtcgact tgctcctctg aaagtacttt tagaggagct gtttgacttt
     7381 gctagttttt gaaactgaaa tctattatac tacaaactat tgaaagcgtt ttaattttaa
     7441 ggtataataa tctcatagaa ataaagaaaa ggaggaaaga ggatgccaca gattagcaaa
     7501 gaagccttga ttgagcaaat caaagatgga atcatcgttt cttgtcaggc tcttcctcat
     7561 gaaccgcttt atacagaagc gggaggggtg attcccttgc tggtcaaagc ggctgagcaa
     7621 ggtggagcag tcggtatccg agcaaacagt gttcgcgata tcaaggaaat taaggaagtc
     7681 actaaacttc caatcattgg gattatcaaa cgtgattatc cacctcagga acccttcatc
     7741 acggctacta tgaaagaagt tgatgaattg gcagaactgg acatcgaggt gattgctctg
     7801 gattgtacca agcgtgaacg ctacgatggt ttggaaattc aagagttcat tcgtcaggtt
     7861 aaggagaaat atcctaatca gcttttgatg gctgatacta gtatcttcga agaagggcta
     7921 gcagctgtag aagcaggaat tgactttgtc ggaacaacct tatcaggcta cacatcctac
     7981 agtccaaaag tagacggtcc agattttgaa ttgattaaga aactctgtga tgctggtgta
     8041 gatgtcattg cagaaggaaa aattcataca ccagaacaag ccaaacaaat ccttgaatat
     8101 ggagtgcgag gcatcgttgt tggtggcgcc attactagac caaaagagat tacagaacgc
     8161 ttcgttgcta gtcttaaata agatgtgagg gggagtttta tgtttaaagt tttacaaaaa
     8221 gttggaaaag cttttatgtt acctatagct atacttcctg cagcaggtct acttttgggg
     8281 attggtggtg cactttcaaa cccaaccacg atagcaactt atccaatact agacaatagt
     8341 atttttcaat caatattcca agtaatgagc tctgcaggag aggttgtatt cagtaatttg
     8401 tcactacttc tctgtgtggg attatgtatt ggcttagcga aacgagataa aggaaccgct
     8461 gcgttagcag gagtaactgg ttacttagtt atgactgcaa cgatcaaagc tttggtaaaa
     8521 ctttttatgg cagaaggatc tgcaattgat actggagtta ttggagcatt agttgtcgga
     8581 atagttgccg tatatttgca caaccgatat aacaatattc aattaccttc cgctttagga
     8641 ttctttggag gttcacgctt cgttcctatt gttacatcgt tctcttctat cttgattggc
     8701 tttgtcttct ttgttatttg gccacctttc caacaacttc ttgtttctac aggtggatat
     8761 atttctcagg cgggtccaat tggaactttt ctatatggat ttttaatgag actttctgga
     8821 gcagtaggct tacatcatat aatttaccct atgttttggt atactgaact tggtggtgtt
     8881 gaaactgttg caggacaaac agtggttgga gctcaaaaaa tattttttgc tcaattagcc
     8941 gatttggccc attctggatt atttacagaa ggaacaaggt tttttgcagg tcgtttctca
     9001 acaatgatgt tcggtttacc ggctgcctgt ttagcgatgt accatagtgt tcctaaaaat
     9061 cgtcgtaaaa aatacgcggg tttgtttttt ggagttgctt taacatcttt tattaccggt
     9121 attacagaac caattgaatt tatgtttcta ttcgtcagtc cggttctata tgttgttcac
     9181 gcattccttg atggtgttag cttctttatt gcagacgtct taaatatttc aataggaaac
     9241 acattttcag gaggtgtaat cgatttcact ttatttggaa ttttgcaggg gaacgctaag
     9301 acgaattggg ttcttcagat tccatttgga cttatttgga gtgttttgta ttatattatt
     9361 tttagatggt tcattactca attcaacgtt ctaacgccag ggcgaggaga agaagtagat
     9421 tctaaagaaa tttctgaatc cgcagattca acttcaaata ctgcagatta tttaaaacag
     9481 gatagcctac aaattatcag agccttgggt ggatcaaata atatagaaga tgtagatgct
     9541 tgtgtgacac gtttacgtgt agctgtaaaa gaagttaatc aagttgataa agcactttta
     9601 aaacaaattg gtgcagttga tgtcttagaa gtgaagggtg gcattcaagc aatctatgga
     9661 gcaaaagcaa tcttatataa aaatagtatt aatgaaattt taggtgtaga tgattaagta
     9721 cttactgact taataaaaaa cagaggagag tgatggatga gtaggatgaa atgaaatcgc
     9781 atacaagaaa taaagaactc attatccaag ttggatacgc ttattacata ggagaataca
     9841 aatgaaattt agaaaattag cttgtacagt acttgcgggt gctgcggttc ttggtcttgc
     9901 tgcttgtggc aattctggcg gaagtaaaga tgctgccaaa tcaggtggtg acggtgccaa
     9961 aacagaaatc acttggtggg cattcccagt atttacccaa gaaaaaactg gtgacggtgt
    10021 tggaacttat gaaaaatcaa tcatcgaagc gtttgaaaaa gcaaacccag atataaaagt
    10081 gaaattggaa accatcgact tcaagtcagg tcctgaaaaa atcacaacag ccatcgaagc
    10141 aggaacagct ccagacgtac tctttgatgc accaggacgt atcatccaat acggtaaaaa
    10201 cggtaaattg gctgagttga atgacctctt cacagatgaa tttgttaaag atgtcaacaa
    10261 tgaaaacatc gtacaagcaa gtaaagctgg agacaaggct tatatgtatc cgattagttc
    10321 tgccccattc tacatggcaa tgaacaagaa aatgttagaa gatgctggag tagcaaacct
    10381 tgtaaaagaa ggttggacaa ctgatgattt tgaaaaagta ttgaaagcac ttaaagacaa
    10441 gggttacaca ccaggttcat tgttcagttc tggtcaaggg ggagaccaag gaacacgtgc
    10501 ctttatctct aacctttata gcggttctgt aacagatgaa aaagttagca aatatacaac
    10561 tgatgatcct aaattcgtca aaggtcttga aaaagcaact agctggatta aagacaattt
    10621 gatcaataat ggttcacaat ttgacggtgg ggcagatatc caaaactttg ccaacggtca
    10681 aacatcttac acaatccttt gggcaccagc tcaaaatggt atccaagcta aacttttaga
    10741 agcaagtaag gtagaagtgg tagaagtacc attcccatca gacgaaggta agccagctct
    10801 tgagtacctt gtaaacgggt ttgcagtatt caacaataaa gacgacaaga aagtcgctgc
    10861 atctaagaaa ttcatccagt ttatcgcaga tgacaaggag tggggaccta aagacgtagt
    10921 tcgtacaggt gctttcccag tccgtacttc atttggaaaa ctttatgaag acaaacgcat
    10981 ggaaacaatc agcggctgga ctcaatacta ctcaccatac tacaacacta ttgatggatt
    11041 tgctgaaatg agaacacttt ggttcccaat gttgcaatct gtatcaaatg gtgacgaaaa
    11101 accagcagat gctttgaaag ccttcactga aaaagcgaac gaaacaatca aaaaagctat
    11161 gaaacaatag tccttagtta ttctataaaa agtagttttt taaagaacct aagagtgtat
    11221 accccctttt ccctctacac agatagtgta agaaaagggg gcttttgttt aaaatgtaag
    11281 aaactgtcac gaaattaaaa tgaagttctt acataagcga atcataaaaa atttcatttt
    11341 gattttaaaa cagttcaaga aagtcaaaaa attattctat ttgaaagaga ggtgccgact
    11401 gtgaaagtca ataaaatccg tatgcgggaa acagtgattt cctacgcttt cctagcacca
    11461 gtattattct tctttgtcat ctttgtgttg gctccgatgg tgatgggctt cattacaagt
    11521 ttctttaact actcaatgac taaatttgag tttgtaggct tggataacta tatccgtatg
    11581 tttaaagatc ctgtctttac aaaatctctg attaacacag ttattttggt tattggatct
    11641 gtaccagttg ttgttctatt ctcactcttt gtagcatctc agacctatca tcaaaatgtc
    11701 attgccagat ccttctaccg tttcgtcttc ttccttcctg ttgtaacggg tagtgttgcc
    11761 gtgacagttg tttggaaatg gatttatgac ccactatcag ggattctaaa ctttgtcctt
    11821 aagtccagcc acatcatcag ccaaaacatt tcttggttgg gagataaaaa ctgggcattg
    11881 atggcgatta tgattattct cttgaccact tcagttggtc agcccatcat cctttatatc
    11941 gctgccatgg ggaatattga caattcactg gttgaagcgg cgcgtgttga tggtgcaact
    12001 gagtttcaag ttttttggaa gattaaatgg ccaagccttc ttccaacaac tctttatatt
    12061 gcaatcatca caacaattaa ctcattccag tgtttcgcct tgattcagct tttgacatct
    12121 ggtggtccaa actactcaac aagtaccttg atgtactacc tttacgaaaa agccttccaa
    12181 ttgacagaat acggctatgc caacacaatt ggtgtcttct tggcagtcat gattgctatc
    12241 gtaagctttg ttcaatttaa agtacttgga aacgacgtag aatactaaag aaaggagaca
    12301 gctatgcaat ctacagaaaa aaaaccatta acagccttta ctgttatttc aacaatcatt
    12361 ttgctcttgt tgactgtgct gttcatcttt ccattctact ggattttgac aggggcattc
    12421 aaatcacaac ctgatacaat tgttattcct cctcagtggt tccctaaaat gccaaccatg
    12481 gaaaacttcc aacaactcat ggtgcagaac cctgccttgc aatggatgtg gaactcagta
    12541 tttatctcat tggtaaccat gttcttagtt tgtgcaacct catctctagc aggttatgta
    12601 ttggctaaaa aacgtttcta tggtcaacgc attctatttg ctatctttat cgctgctatg
    12661 gcgcttccaa aacaagttgt ccttgtacca ttggtacgta tcgtcaactt catgggaatc
    12721 catgatactc tctgggcagt tatcttgcct ttgattggat ggccattcgg tgtcttcctc
    12781 atgaaacagt tcagtgaaaa tatccctaca gagttgcttg aatcagctaa aatcgacggt
    12841 tgtggtgaga ttcgtacctt ctggagtgta gccttcccga ttgtgaaacc agggtttgca
    12901 gcccttgcaa tctttacctt catcaatact tggaatgact acttcatgca attggtaatg
    12961 ttgacttcac gtaacaattt gaccatctca cttggggttg cgaccatgca ggctgaaatg
    13021 gcaaccaact atggtttgat tatggcagga gctgcccttg ctgctgttcc aatcgtcaca
    13081 gtcttcctag tcttccaaaa atccttcaca cagggtatta ctatgggagc ggtcaaagga
    13141 taatactctg cgaaaatctc ttcaaactac gtcagcttca ccttgccata cttaagtatt
    13201 gcctgcggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    13261 atcaagatac agaagtatat tttatagatt tagagaatat agaggttata agtgtctaca
    13321 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttataaa cttaagaatg
    13381 gttttagtta actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    13441 caccttttac aaagggattc atcctaattt agacaaggct atcgactatc tctaccaaca
    13501 tcgtaaggat tctttcgaat taggaaagta tgatattgat ggagataaag tctttctagt
    13561 tgttcaggaa aatgtcctca atcaagctga aaatgatcaa tttgagtatc ataagaacta
    13621 tgcagatttg catttgctgg tagaaggaca tgaatattcg agctacggtt cacgtatcaa
    13681 agacgaggca gtagcattcg acgaagcgag tgacattggc tttgttcatt gtcatgaaca
    13741 ctacccactc ttgttgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca
    13801 gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaattttgat
    13861 tgattaaaaa taggatgaat tgtttttttg taaagctttg ataatactct accatgaaat
    13921 tgatctttgt gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta
    13981 tgctgcaaga gctagtttct tagatggaca ggggattaca gttgatgaga tggcttggat
    14041 aattaggggc attgtgaatg cattgattgg tagatacata aaattaggta cttatgcggc
    14101 taagtatggt attagtatgg cacgctcgat cttaagtagg gtagctgcaa ctgcagcagc
    14161 aagagtagga ttactgacca agatttctgg atggatttta cgagtagctg tgaatgtagc
    14221 tgatgtatat ggtaattttg ccaacaatat tgctgcagct tgggatgcat atgataaaat
    14281 tcctaacaat ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt
    14341 attgaatatg ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt
    14401 tgataggcat acttggagta ctattttaat tgcttcgctg ttcggggtat atgattataa
    14461 gcccatagat aaaaatagaa aaaagtccaa aagaaaaaat agatttgttc atggtaggga
    14521 cttatgaaag ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc
    14581 aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag ataactttct
    14641 catgcgtttt agtgagaagg tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc
    14701 ttgtttaccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga
    14761 agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa
    14821 tctgaaacta ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc
    14881 agatctctat cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg
    14941 tttaggtatt ctgatttttc ttactatcgt gatgctggct agttacccta tcgcggcacg
    15001 ttatgaccta tcttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt
    15061 tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc
    15121 cgccttcagt ctactcttag gtggctcagt cttcctactt tttgggtttg gactattggt
    15181 ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg agctttattt
    15241 ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta aaatctaagt
    15301 gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc
    15361 tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga
    15421 aggtgtcatt ccagccttct acgcatgtta tgatgatcaa ggagaagtaa gcccagaacg
    15481 tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg
    15541 ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt tggaagaagt
    15601 catggcggta gccaaaggta aattgaccat tattgctcat gttgcctgca acaatactaa
    15661 agacagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat
    15721 tccaccaatt tatttccgct tgccagaata ctcagttgcc aaatactgga acgatatcag
    15781 ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc
    15841 tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa
    15901 ctcttctatg ccagttcaag atatccaaac ctttgtcagc cttggtgggg aagaccatat
    15961 cgtctttaat ggtcctgatg agcagttcct aggaggacgc ctcatgggtg ctagggctgg
    16021 tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc
    16081 ggataaggac ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa
    16141 actcacttct gctcatggaa atatgtacgg tgtcattaaa gaagtcttga aaatcaatga
    16201 agtcttgaat attggatctg ttcgttcacc attgacacca gtgactgaag aagatcgtcc
    16261 agttgtagaa gcggctgctg ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa
    16321 aaggaggtat ttatgacata ttacgttgca attgatatcg gtggaaccaa catcaagtat
    16381 ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat
    16441 aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa
    16501 ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag
    16561 attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa aaaggaaatc
    16621 gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct
    16681 gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaacc
    16741 ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag caattcagcc
    16801 tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc aagacttggc ttctacaaca
    16861 gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccgt
    16921 agaattttca aagaagccac tgaaggaaac aaaatctgca tggaaggtat tgaccgtatg
    16981 gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc agaagtggtt
    17041 attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat ccgtacagcc
    17101 ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac
    17161 caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt
    17221 ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt
    17281 attttcccag tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta
    17341 ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc gttggatata
    17401 ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt
    17461 gggaacactt gtaaagagta cagtctttgc ccccatctcc ttagcatcta atagactatc
    17521 taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat tttcatccat
    17581 gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag
    17641 tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa
    17701 gtagatacgc tcagcatctt cgattagctg ggcaattcgt tctagttgga tttcgtcaat
    17761 caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg
    17821 actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa
    17881 ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat
    17941 atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa
    18001 aaaatagcga gcgatttctt gttctaggtc tgtcatttct tcaaaatgtg aatcaatgat
    18061 agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat actggaagac
    18121 tagatcagag aatagtcaca cttcattata acacataata taaggataga taaataaaaa
    18181 cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct
    18241 actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat
    18301 gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat
    18361 tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt
    18421 ttacgaaaaa aagctagctt cagctagtca gaccaagatt acaagcagtt cagcccgtgg
    18481 ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc
    18541 ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact
    18601 gacttatgtg agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt
    18661 ggctgatcct gaaatctata aaaaaatagt ggaagctctc ccaagtgaga aacgcttgga
    18721 ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtaca
    18781 aacgagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt
    18841 aaatgctgtt ggaaactttg cgacaggaac cattgcgaca gatcctctaa atgattctca
    18901 ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg
    18961 ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa
    19021 agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga
    19081 ccgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc
    19141 ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga
    19201 aggtagtaag ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga
    19261 tgctttactg aaaagttatt tcaattctga gctagaaaat ggtggagcca agtattctga
    19321 aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat
    19381 taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt
    19441 ctttgttcca ggttcggttg tcaaggcggc gaccatcagc tcaggttggg aaaatggagt
    19501 cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat
    19561 caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga
    19621 gtattcatca aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca
    19681 acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac
    19741 ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg
    19801 atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga
    19861 taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaata atggtgttcg
    19921 tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga
    19981 cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat
    20041 gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtggat tgacaactgg
    20101 acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta cagccgaaag
    20161 ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga
    20221 taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa caaatggtgt
    20281 aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaatta
    20341 gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt
    20401 taccaggtat cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg
    20461 ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt
    20521 gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact gatccgactc
    20581 gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata
    20641 tccaagaata ccatggactc tatcatgtcc ttcatggcct catttctcct atgaatggta
    20701 tcagtccgga cgatatcaat ctcaagagcc ttatgactcg tcttatggat agtgaggttt
    20761 cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacttcc atgtatcttt
    20821 cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg
    20881 gagcggacat tgagtatgcg gacgaagtga cactcttacg agccattgaa aatcggacag
    20941 agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga
    21001 aaatcgttcc tatcggcctc tttttgtata gtgtgatgag taggctcagg ttcaagtttt
    21061 aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat
    21121 aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct
    21181 gtcctttcag ctgagagtgt catgcgtgcg gtcgattacg accgtttcac agtcaagact
    21241 ttctttatca gtcagtcagg tgactttatc aaaacacagg aatttagtca tgctccgggg
    21301 caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt
    21361 gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat
    21421 ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg
    21481 tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt
    21541 gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatcgctgaa
    21601 gtggaagaaa aattggctta tccagtcttc actaagccgt caaacatggg gtctagtgtc
    21661 ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga
    21721 tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc
    21781 ttgggtaact acgatgtcaa gagcacgcta ccaggagaag ttgtcaagga cgttgccttt
    21841 tatgactacg atgccaagta tattgataac aatattacta tggatattcc tgccaaaatc
    21901 agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt
    21961 ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac
    22021 gagctcaata ctatgccagg tttcacccag tggtctatgt acccactact ttgggacaat
    22081 atggggatca gctacccaaa actaatcgag cgtttggttg accttgccaa ggaaagtttt
    22141 gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac
    22201 tgcacggtga ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa
    22261 caatccatga aattgcccaa gttgttggag ccaaaaatga tatcagtatc tttgaggaca
    22321 cccagttaga aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc
    22381 cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag
    22441 cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt
    22501 tgacagcctt tcaatcctta gcatcctact atcttgaaaa aacgactgtt gatgtctttg
    22561 ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa
    22621 caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca
    22681 cagttcttca tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact
    22741 tgggcgatat tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg
    22801 ttggagaagc ccatttggcc tttttcaaag accgttcaga gattgctaag ggaaaaatgc
    22861 aaattgcaga cggaatggct tcaggttcct tgcttttagc gccggctgac cctatcgtag
    22921 aggactattt gccaactgat aaaaaggtgg ttcgttttgg gcaaggggca gagctggaaa
    22981 ttactgactt ggttgagcgc aaagatagtc tgaccttcaa ggccaatttc ttagagcaag
    23041 cccttgattt gccagtaact ggcaagtaca atgcgacaaa tgctatgatt gcatcctatg
    23101 ttgccttgca agaaggagtt tcagaggagc aaattcgttt ggccttccaa gatcttgaat
    23161 tgacgcgtaa ccgtaccgag tggaagaaag cagccaatgg agcagatatc ctgtcagatg
    23221 tttacaatgc caatccaact gctatgaaac tgattttaga gactttctct gccattccag
    23281 ccaatgaagg tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt
    23341 ctgttcaact tcataatcag atgattttga gcctttctcc agatgtgctt gataccgtga
    23401 ttttctatgg acaagatatt gctcagttgg ttcaattggc cagtcaaatg ttcccaatcg
    23461 gccacgttta ctacttcaag aaaacagaag accaggatca atttgaagac ctagtcaagc
    23521 aggtcaagga aagccttgga gcccatgacc aaatcctgct caaaggctct aactctatga
    23581 atctagccaa gttggtagaa agtttagaaa atgaagacaa gtgattttgt caagtatttg
    23641 caaagaatga ttgccattac agatactggc ttaaccttta caaaagatcc gtttgaccgt
    23701 gagcgctacg aagacttgcg aagtctgtta tctgaaatgt tgaatcaagc atcagacctt
    23761 gattccgaag aagtggcaga agtcttgaag ccaacttctg cttatgcgac tccgttaatg
    23821 gacgtccgtg cttggattgt tgaggatgag aagatttgtc tggttagggg acaaggagag
    23881 gatagttggg ctttgccagg tggctttggt gaagtcggct attctccaac agaaaatatt
    23941 ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt
    24001 tttgatacca atcgtttcca actacagagc aaacagtata caaagtttgt ttttggatgt
    24061 aagcttcttg atggacaatt ccaagaaaat caagaaattg ctgaccttca attttttgcc
    24121 attgaccaac tgccgaactt atctgaaaaa cgcattacca aggagcaaat agagcttctt
    24181 tggcaggttt atcaaggtca tagggggcaa tatcttgact aagaagatga ttatcgtatt
    24241 tctaaatcca tttttaacaa ctagcatggt ataataatat gcaggaaaat tttgaattat
    24301 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
    24361 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
    24421 gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt
    24481 cagttaatcc ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta
    24541 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcaatccaaa
    24601 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
    24661 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
    24721 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
    24781 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaattta
    24841 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
    24901 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
    24961 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
    25021 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
    25081 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
    25141 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
    25201 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
    25261 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
    25321 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
    25381 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
    25441 gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
    25501 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
    25561 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
    25621 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
    25681 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
    25741 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
    25801 caatggttca gtctgttttg aatgaagggg aacgtgaatt tggtgctaca gtgattgata
    25861 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
    25921 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
    25981 gcaaattagc ggaaggcttg aaactgaatt acggggaagc ctatccgcct cttgcaagca
    26041 aagaaacctt ccaagtagag gttattggag aagtggaagc agtcgaagtg acggaagcct
    26101 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
    26161 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
    26221 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
    26281 ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat
    26341 ttgcgggtca attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg
    26401 acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac
    26461 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac
    26521 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
    26581 gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
    26641 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
    26701 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
    26761 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
    26821 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
    26881 agcgaagaaa cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
    26941 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtattgc caaagattta
    27001 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
    27061 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
    27121 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
    27181 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
    27241 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
    27301 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
    27361 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
    27421 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
    27481 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
    27541 gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
    27601 gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc tcattcacat
    27661 ggctttgatc gtcattttga tatggcagaa acagctgaat tgccaaaaca aaatccacgt
    27721 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
    27781 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
    27841 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
    27901 agaaaataca gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctcatcgaga
    27961 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
    28021 cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
    28081 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
    28141 taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact cagtaaagct
    28201 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
    28261 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
    28321 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
    28381 tagcagtgag cagttgaaag agattttcaa ggcggcccaa gatttacaaa gagaaattca
    28441 agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta
    28501 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
    28561 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
    28621 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactt cagtaaattc
    28681 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa
    28741 caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    28801 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    28861 tgatttattg gcaggaaacg aaagtatctt gattgacttt cagtatatga cagaggtgca
    28921 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    28981 aaaggtagct tctaccatgt atttgttgac accagtgaac gttattgtaa atgttgaaga
    29041 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    29101 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    29161 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    29221 cgttggattg tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag
    29281 atagcgggtc ttgatttatc tgtttgggtt gcgattgttt tggttcgatt tttaggagaa
    29341 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    29401 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    29461 atgctccttt tttaactcct tttttaactc cttttatcaa tcctcatcag gagaagctat
    29521 taaagatttt ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga
    29581 gtgagtatgt tcgagtttta ttatacccag attatttcca accagagttt tcagattttg
    29641 aaatatctct ccaggaaatt gtgtattcca ataaatttga acatttaacg catgctaaga
    29701 ttttagggac agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag
    29761 tagatgaaga acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg
    29821 gactaaagaa aattggtcgt atacctgttt cgctggagga acgtcctttc accgagaaaa
    29881 tagataagct agaacagtat cgagaactgg atttatctgt gtctagtttt cgattagatg
    29941 ttcttttatc aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga
    30001 aacttgtcca agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag
    30061 acttgattag tgtgagaaaa tttggtcgct tgagattact tcaagataag ggacaaacga
    30121 aaaaagagaa gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc
    30181 aattacatca ttagaaataa aggacaagac ttttggaact cgattcagag gttttgatcc
    30241 agaagaagtc gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc
    30301 gaatcatgat aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga
    30361 aataaaagat tcattgagcc agtctgtatt gattgctcag gatacagctg agagagtgaa
    30421 acaggcggcg catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg
    30481 cttgttggaa gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc
    30541 taagaaagtc gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg
    30601 tctcaaatct acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat
    30661 tctccgtcca acagctactt atcttcaaac cagtgatgaa gcctttaaag aagtggttag
    30721 cgaagtactt ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg
    30781 tcagttctct caagcagaaa tggcagaatt acaagctcgt attgaggtag ccgataaaga
    30841 attgtctgaa tttgaagctc agattaaaca ggaagtggaa gctccaactc ctgtagtgag
    30901 tcctcaagtt gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa
    30961 gtagctccaa tgcatccgat aggtccaaca ccagctacag aaactgttga ttcaataccg
    31021 ggatttgaag caccgcaaga atctgttaca attttataag aaatattctg agaacaatat
    31081 cttatcctta tatttccagc gagcaggaga tggtgtgagt cctgtaatcc ctattgataa
    31141 gattatcctc tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg
    31201 ggataagagg gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc
    31261 ctttttggaa gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc
    31321 aaagacaccc ttaatcttgg gaaaactgaa ttcccaatgc gtgcaggcct tcctaccaaa
    31381 gagccagttt ggcaaaagga atgggaagat gcaaaacttt atcaacgtcg tcaagaattg
    31441 aaccaaggaa aacctcattt caccttgcat gatggccctc catacgctaa cggaaatatc
    31501 cacgttggac atgctatgaa caagatttca aaagatatca ttgttcgttc taagtctatg
    31561 tcaggatttt acgcaccatt tattcctggt tgggatactc atggtctgcc aatcgagcaa
    31621 gtcttgtcaa aacaaggtgt caaacgtaaa gaaatggact tggttgagta cttgaaactt
    31681 tgccgtgagt acgctctttc tcaagtagat aaacaacgtg aagattttaa acgtttgggt
    31741 gtttctggtg actgggaaaa tccatatgtg accttgactc ctgactatga agcagctcaa
    31801 attcgtgtat ttggtgagat ggctaataag ggttatatct accgtggtgc taagccagtt
    31861 tactggtcat ggtcatctga gtcagcactt gctgaagcag agattgaata ccatgacttg
    31921 gtttcaactt ccctttacta tgccaacaag gtaaaagatg gcaaaggagt tctagataca
    31981 gatacttata tcgttgtctg gacaacgact ccatttacca tcacagcttc tcgtggtttg
    32041 acggttggtg cagatattga ttacgttttg gttcaacctg ctggtgaagc tcgtaagttt
    32101 gtcgttgctg ctgaattatt gactagcttg tctgagaaat ttggctgggc tgatgttcaa
    32161 gttttggaaa cttaccgtgg ccaagaactc aaccacatcg taacagaaca cccatgggat
    32221 acagctgtag aagagttggt aattcttggt gaccacgtta cgactgactc tggtacaggt
    32281 attgtccata cagcccctgg ttttggtgag gacgattaca atgttggtat tgctaataat
    32341 cttgaagtcg cagtgactgt tgatgaacgt ggtatcatga tgaagaatgc tggtcctgaa
    32401 tttgaaggtc aattctatga aaaggtagtt ccaactgtta ttgaaaaact tggtaacctc
    32461 cttcttgccc aagaagaaat ctctcactca tatccatttg actggcgtac taagaaacca
    32521 atcatctggc gtgcagttcc acaatggttt gcctcagttt ctaaattccg tcaagaaatc
    32581 ttggacgaaa ttgaaaaagt gaaattccac tcagaatggg gtaaagtccg tctttacaat
    32641 atgatccgtg accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt
    32701 cctatcttct acgctgaaga tggtacagct atcatggtag ctgaaactat tgaacacgta
    32761 gctcaacttt ttgaagaata tggttcaagc atttggtggg aacgtgatgc caaagacctc
    32821 ttgccagaag gatttactca tccaggttca ccaaacggcg agttcaaaaa agaaactgat
    32881 atcatggacg tttggtttga ctcaggttca tcatggaatg gagtggtggt aaaccgtcct
    32941 gaattgactt acccagccga cctttaccta gaaggttctg accaataccg tggttggttt
    33001 aactcatcac ttatcacatc tgttgccaac catggcgtag caccttacaa acaaatcttg
    33061 tcacaaggtt ttgcccttga tggtaaaggt gagaagatgt ctaaatctct tggaaatact
    33121 attgctccaa gcgatgttga aaaacaattc ggtgctgaaa tcttgcgtct ctgggtaaca
    33181 agtgttgact caagcaatga cgtgcgtatc tctatggata tcttgagcca agtttctgaa
    33241 acttaccgta agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac
    33301 ccagctcaag atacagtcgc ttacgatgag cttcgttcag ttgataagta catgacgatt
    33361 cgctttaacc agcttgtcaa gaccattcgt gatgcctatg cagactttga attcttgacg
    33421 atctacaagg ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt
    33481 gccaaagatg ttgtttacat tgaaggtgcc aaatcactgg aacgccgtca aatgcagact
    33541 gtcttctatg acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact
    33601 gcggaagaaa tctggtcata tcttgagttt gaaacagaag acttcgtcca attgtcagaa
    33661 ttaccagaag ttcaaacttt tgctaaccaa gaagaaatct tggatacatg ggcagccttc
    33721 atggactttc gtggacaagc acaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc
    33781 ggtaaatcac ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc
    33841 gaagcagtaa acagcaatgt agcacaactt ttgatcgtgt ctgagttgac catcgcagaa
    33901 ggaccagctc cggaagctgc ccttagcttc gaagatgtag ccttcacagt tgaacgtgct
    33961 actggtgaag tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac
    34021 caggcagtta tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc
    34081 gcagaaggat ttgaagagaa ataagattga aaagtctagg caaaattcaa tttgagaaga
    34141 aaagacaact aattttatag tctattaaac gcattgtatc acgtttttga atacctgata
    34201 tgatgcgttt tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga
    34261 atcaaagaga aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg
    34321 ataagattgg taaatagtgt aatattttta caacaataaa tttatatagt ta
//
LOCUS       DAVMCN010000017        30579 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVMCN010000017 DAVMCN010000000
VERSION     DAVMCN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.017"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(304..2562)
                     /gene="glgP"
                     /locus_tag="VYP85_000973"
     CDS             complement(304..2562)
                     /gene="glgP"
                     /locus_tag="VYP85_000973"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1881509.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(2588..4105)
                     /gene="malQ"
                     /locus_tag="VYP85_000974"
     CDS             complement(2588..4105)
                     /gene="malQ"
                     /locus_tag="VYP85_000974"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1881510.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            4655..5926
                     /locus_tag="VYP85_000975"
     CDS             4655..5926
                     /locus_tag="VYP85_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1881511.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6037..7329
                     /locus_tag="VYP85_000976"
     CDS             6037..7329
                     /locus_tag="VYP85_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1881512.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            7331..8173
                     /locus_tag="VYP85_000977"
     CDS             7331..8173
                     /locus_tag="VYP85_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1881513.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            8426..9226
                     /locus_tag="VYP85_000978"
     CDS             8426..9226
                     /locus_tag="VYP85_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1881514.1"
                     /translation="MLPYPFSYFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYAGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKENKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            9236..10222
                     /locus_tag="VYP85_000979"
     CDS             9236..10222
                     /locus_tag="VYP85_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1881515.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            10358..10438
                     /locus_tag="VYP85_000980"
                     /pseudo
     CDS             10358..10438
                     /locus_tag="VYP85_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10558..11499)
                     /locus_tag="VYP85_000981"
     CDS             complement(10558..11499)
                     /locus_tag="VYP85_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1881516.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(11477..13240)
                     /gene="aspS"
                     /locus_tag="VYP85_000982"
     CDS             complement(11477..13240)
                     /gene="aspS"
                     /locus_tag="VYP85_000982"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1881517.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(13472..13549)
                     /locus_tag="VYP85_000983"
                     /pseudo
     CDS             complement(13472..13549)
                     /locus_tag="VYP85_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(13591..13821)
                     /locus_tag="VYP85_000984"
     CDS             complement(13591..13821)
                     /locus_tag="VYP85_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881518.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(13839..14480)
                     /locus_tag="VYP85_000985"
     CDS             complement(13839..14480)
                     /locus_tag="VYP85_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1881519.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(14492..15226)
                     /locus_tag="VYP85_000986"
     CDS             complement(14492..15226)
                     /locus_tag="VYP85_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1881520.1"
                     /translation="MKKKRRLLFLMSIVFGGVLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(15229..15426)
                     /locus_tag="VYP85_000987"
     CDS             complement(15229..15426)
                     /locus_tag="VYP85_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881521.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(15426..15632)
                     /locus_tag="VYP85_000988"
     CDS             complement(15426..15632)
                     /locus_tag="VYP85_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881522.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(15642..15956)
                     /locus_tag="VYP85_000989"
     CDS             complement(15642..15956)
                     /locus_tag="VYP85_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881523.1"
                     /translation="MWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKKPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(16211..17500)
                     /locus_tag="VYP85_000990"
     CDS             complement(16211..17500)
                     /locus_tag="VYP85_000990"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1881524.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPAIDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(17578..18825)
                     /locus_tag="VYP85_000991"
     CDS             complement(17578..18825)
                     /locus_tag="VYP85_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1881525.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAIWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            complement(19015..19866)
                     /gene="rgg"
                     /locus_tag="VYP85_000992"
     CDS             complement(19015..19866)
                     /gene="rgg"
                     /locus_tag="VYP85_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1881526.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEKFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            19990..20331
                     /locus_tag="VYP85_000993"
     CDS             19990..20331
                     /locus_tag="VYP85_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1881527.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            20389..20469
                     /locus_tag="VYP85_000994"
                     /pseudo
     CDS             20389..20469
                     /locus_tag="VYP85_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20675..22378)
                     /gene="ilvD"
                     /locus_tag="VYP85_000995"
     CDS             complement(20675..22378)
                     /gene="ilvD"
                     /locus_tag="VYP85_000995"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1881528.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(22611..23543)
                     /locus_tag="VYP85_000996"
     CDS             complement(22611..23543)
                     /locus_tag="VYP85_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1881529.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(23540..24397)
                     /locus_tag="VYP85_000997"
     CDS             complement(23540..24397)
                     /locus_tag="VYP85_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1881530.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(24401..25747)
                     /locus_tag="VYP85_000998"
     CDS             complement(24401..25747)
                     /locus_tag="VYP85_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1881531.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(25760..26044)
                     /locus_tag="VYP85_000999"
     CDS             complement(25760..26044)
                     /locus_tag="VYP85_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1881532.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(26048..28078)
                     /locus_tag="VYP85_001000"
     CDS             complement(26048..28078)
                     /locus_tag="VYP85_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1881533.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            28269..29276
                     /locus_tag="VYP85_001001"
     CDS             28269..29276
                     /locus_tag="VYP85_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1881534.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIVDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            29279..29479
                     /locus_tag="VYP85_001002"
     CDS             29279..29479
                     /locus_tag="VYP85_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1881535.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            29631..29813
                     /gene="rpmF"
                     /locus_tag="VYP85_001003"
     CDS             29631..29813
                     /gene="rpmF"
                     /locus_tag="VYP85_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1881536.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            29829..29978
                     /gene="rpmG"
                     /locus_tag="VYP85_001004"
     CDS             29829..29978
                     /gene="rpmG"
                     /locus_tag="VYP85_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1881537.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(30470..>30579)
                     /locus_tag="VYP85_001005"
     CDS             complement(30470..>30579)
                     /locus_tag="VYP85_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1881538.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         9462 a         6547 c         5517 g         9053 t
ORIGIN      
        1 atagatgtga ggtaaccaac tacgaaaaaa tataaggctg aagacagtaa aaaccagcat
       61 ttaaagcctt cactgtatct aggatttccc tatttttaga caagattgac ccaaatccac
      121 agcatttaaa aaagcgaatt tcaattgaaa ctcgcttttt tacaagatgt attagtataa
      181 atttgtatct tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
      241 tcaaagcacc gctttgaggt tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga
      301 gtattagttc aagtgccaga tgtcttcgtt atactgagcg attgtacggt cagatgagaa
      361 gaatcctgct ttagaaatgt taacgatgac tttatccaac catgcgtcac ggtcttcgta
      421 gtcagcaagc atttgctctt tgactttgat gtagtcttcc aaatcaagaa gagtcatgaa
      481 ccagtctttg ttgatcaatt cattgtaaag acgttccaag cgctctttgt ttccagctgc
      541 aagaactgca tcactaacga tgaagtcaac caatggtttg atagcttcac gagcgtagaa
      601 ttcgcttgat ttgtaagctg cttttgcgta aaggtcgata acagtttctg aattttcacc
      661 gaagatgtag atgttttctt ctccaaccaa ctcagcgatt tccacgttag caccgtccat
      721 agtaccaagt gtcaaagctc cgttcaacat gaatttcatg ttaccagtac ctgaagcttc
      781 tttagaagca agtgagattt gttctgagat atcacatgct gggataagga aacttgctgc
      841 agtaacgttg tagttttcaa ccataactac ttgcaagtgt ggagctactg ctggatcgtt
      901 agcaataact tctgacatgc aaaggattaa atggataatg tcttgagcga ttgtgtaggc
      961 tggagctgct ttaccaccaa agaagattgt gattggacga gcagggatgt taccagcttt
     1021 gatgtcaagg tatttgtgga tcacgtacaa agcgttcatt tgttggcgtt tgtactcgtg
     1081 aagacgtttg atttggatat caaagataga atttggattg atttccacac cttggtgttc
     1141 tttcaagtga cgagccaatt tacgtttgtt gtgagccttg atgctttcca atttttcttt
     1201 gacagctgct ttgtcttcat aagacaacag tttttcaagc tcatctgctt catggtgcca
     1261 accatctcca agaatctcat ccaagtagtg agacaatctt gggttagcat gcataagcca
     1321 acgacggaaa gtgataccgt ttgttttgtt gttgaacttt tctgggtaaa ggtcgtagaa
     1381 ggctttcaac tcagaatttt tcaagatttc agtatggagt gctgcaaccc cgttaacact
     1441 gtatccgtag tggatatcca tgtgagccat gtgaacacgt ccgctctcat cgatgatttg
     1501 aacagctgga tctttgtact ctgccttcac acgacggtcc aattcttcga tgattggtac
     1561 caagtgagga accacttctt gcaagaattc aagaggccat ttttcaagcg cttcagcaag
     1621 gattgtgtgg ttagtgtagg cagtcatgct acgaacaatt gagattgctt cgtcaagatc
     1681 gataccacgt gcagtcaaaa gacgaatcaa ttcaggaatc accattgatg ggtgagtatc
     1741 gttgatttgg acaactgcgt agtcagcaag gtcatgcaag ttgcttcctt tttcgattgc
     1801 ttcgtcgatg atcaattgcg caccgtttga aaccatgaag tattgttgga agatacggag
     1861 caattcacct tgacggtcac tatcatctgg gtaaaggaag agagttaagt tgcgagcgat
     1921 atctgtcttg tcaaagttga taccatcttt aataatagaa gaatcaactg aatccaagtc
     1981 aaacaaacgc aagcggtttt tagtcgctgt ttcataacca gtaacatcaa tatcgtaaag
     2041 agttgatgtc aaagtaaagt ctgcaaatgg tacttggtag ctacggcttg agcgaaccaa
     2101 ccagttttgc tctgtcaacc atgcatttgg aattgtttct tgttggttgt ttttaagaac
     2161 ttgttggaaa agaccaaagt ggtagttaag accaacaccg tcaccattca aaccaagagt
     2221 agcaattgag tcgataaagc aggcagccaa acgtcccaaa ccaccattac caagagatgg
     2281 ttccaattca acttcttcaa cttcgatcaa gtctttacct gcagctgcaa gttctttttt
     2341 aacatcgtcg taaagaccaa ggttaatcaa gttgtttgac aagagtttac caatcaagaa
     2401 ctcagctgag atgtagtaaa cttttttctt accagtgttg actggttttt ggctgcttgc
     2461 aagcttgctg tagttaagaa gagcaaggta aagctcttca ttgctacatt ctgcaatggt
     2521 tttattgtaa cgattttgta caaattcttg tagtgataac atgtttagtt gtctcctgat
     2581 tattgtctta tttctttaaa tctaccaaat tttcattaat tcggcgataa attgttgtca
     2641 agtcaagcaa accttcctcg acagctggtg tcaattgatc ttcagtcata cgccaagacc
     2701 agtttccacc aagggtagat gggaagttca tacgagctgc ctcatccaat tctagtaaat
     2761 cttgcatagt tgcaattgcc ataaagctaa ctgatgaaaa tactgtacga agcatagcgt
     2821 gtaccactgt ttcgtattct ttacggttcg tgtaacgagc catgtactca cgagtcgcat
     2881 catcaatctc attacggtac caaccaagaa ccgtattgtt atcgtgtgtt cctgtgtaca
     2941 taactgagtt agcaggtgcc aagtgtgggc tatcaatgct ttcgtcttct gggttgaagg
     3001 caaattgaag aatcttcatt cctgggaagc cagtacgttc acgcaattcg atcacttcat
     3061 ctgtcatgaa gccaaggtct tctgcgatga tgtttagctc accaagttct tccttaacgg
     3121 ctgcaaaaag cttgtagcct ggacctttca cccactcacc aggtgctgct gtatcggaac
     3181 cagcagggat ttcccagtaa gattcgaagc cacggaagtg gtcgatacga acgatatcgt
     3241 agattttgaa gctttcacgc aagcgttcaa tccaccattt gtagccgtct ttgtccattg
     3301 cttcccagtc atagattggg ttaccccaaa gctgaccagt tacagaaaac tcatctggtg
     3361 ggcatcctgc gatacaagta gccttaccat tgacatctgt tttgaagaga tgtggatttg
     3421 cccacatatc acttgaatct tccgctacgt agattggcat gtccccaacg atttcgatgt
     3481 ggttgtcgtt agcgtaagct ttcaatttca accattgttg gaagaagaag tattgagtca
     3541 cacggtggta aaccaacttg tctgccaatt gctcacgata gctttcaagt gctgaagctt
     3601 tacgagcacg agcatctgca tctggccatt cagtccaagc aagattgtca aaatactctt
     3661 tgatagccat atactcagca aagagctcaa gccatgattg gttgtcttga gcaaatttct
     3721 caaaatcttt aacatctccg acttcaaaga aacgtttcac cgctttttct aaaagaggac
     3781 gacgtgcata gtagatttta gcatagtcaa cttcagacgc atcgctacca aagtcaactc
     3841 cttcaaggtc acttgcttcc aacaaacctt gctccaccaa gatatctaaa tcgataaaat
     3901 gagtgtttcc tgcgaaggct gagaaagatt ggtaaggaga atccccgtaa ctagttgctc
     3961 ctaatggaag gatttgccag taacgttgtt ttgtacggac caagaaatca acgaagtcgt
     4021 aagcactttg accaaatgat ccgattccgt aagctcctgg aagagaagag atgtgcatca
     4081 acacaccact ttgacgtttt ttcataatag cacctcgtgt gttaaaataa tggaacgttg
     4141 cgtattttgc agacgcaaac gtttgcgtta cttataagta tactcctttt caagcataat
     4201 tgcaagcgtt tttaaaaaac ttttttgatt atttttaagg agactaactc attttagcaa
     4261 agataactta aaactatcta atcctaaggt ttgactctca cgagacagtc tacaaagtac
     4321 aaaacctcct tagggagctt gaatttatat gtaacaaagc acaaacgtcc atagaaaata
     4381 gatagggatt agaaccaggg aggtagcccc tcctggtttc cctctttaga cagattccat
     4441 atatttttat taaaaatact gtattcttat ctatttcata cttttcttct attaaaatgc
     4501 aaaattatgc tatcaaatca agcttaaaaa ttttttaaaa tttttacaaa aaatacttgc
     4561 aaccgttttc tatttgtgct atactaagct cataaaggaa aacgtttgcg tttccttatc
     4621 aataaaactt gctattcttt gggaggaata cactatgtca tctaaattta tgaagagcac
     4681 tgcggtgctt ggaactgtta cacttgctag cttgcttttg gtagcttgcg gaagcaaaac
     4741 tgctgataag cctgctgatt ctggttcatc tgaagtcaaa gaactcactg tatatgtaga
     4801 cgagggatat aagagctata ttgaagaggt tgctaaagct tatgaaaaag aagctggagt
     4861 aaaagtcact cttaaaactg gtgatgctct aggaggtctt gataaacttt ctcttgacaa
     4921 ccaatctggt aatgtccctg atgttatgat ggctccatac gaccgtgtag gtagccttgg
     4981 ttctgacgga caactttcag aagtgaaatt gagcgatggt gctaaaacag acgacacaac
     5041 taaatctctt gtaacagctg ctaatggtaa agtttacggt gctcctgccg ttatcgagtc
     5101 acttgttatg tactacaaca aagacttggt gaaagatgct ccaaaaacat ttgctgactt
     5161 ggaaaacctt gctaaagata gcaaatacgc attcgctggt gaagatggta aaactactgc
     5221 cttcctagct gactggacaa acttctacta tacatatgga cttcttgccg gtaacggtgc
     5281 ttacgtcttt ggccaaaacg gtaaagacgc taaagacatc ggtcttgcaa acgacggttc
     5341 tatcgcaggt atcaactacg ctaaatcttg gtacgaaaaa tggcctaaag gtatgcaaga
     5401 tacagaaggt gctggaaact taatccaaac tcaattccaa gaaggtaaaa cagctgctat
     5461 catcgacgga ccttggaaag ctcaagcctt taaagatgct aaagtaaact acggagttgc
     5521 aactatccca actcttccaa atggaaaaga atatgctgca ttcggtggtg gtaaagcttg
     5581 ggtcattcct caagccgtta agaaccttga agcttctcaa aaatttgtag acttccttgt
     5641 tgcaactgaa caacaaaaag tattatatga taagactaac gaaatcccag ctaatactga
     5701 ggctcgttca tacgctgaag gtaaaaacga tgagttgaca acagctgtta tcaaacagtt
     5761 caagaacact caaccactgc caaacatctc tcaaatgtct gcagtttggg atccagcgaa
     5821 aaatatgctc tttgatgctg taagtggtca aaaagatgct aaaacagctg ctaacgatgc
     5881 tgtaacattg atcaaagaaa caatcaaaca aaaatttggt gaataaaaaa tttgttcaag
     5941 gggggtggaa atcaaatccc cctttgaatt tatcaataga gacacaaata atttagcttt
     6001 cttataaaaa agtagtatcc tatgaaagga gttaatatgg aaaagcaaca acctagtaaa
     6061 gcagccctgc tgtctatcat tcctgggtta ggacagattt acaataaaca aaaagccaaa
     6121 ggttttatct tccttggtgt aaccatcgta tttgtccttt acttcctagc acttgcaacc
     6181 cctgaattga gcaacctcat cactcttggt gacaaaccag gtcgtgataa ttccctcttt
     6241 atgctgattc gtggtgcctt ccatctaatc tttgtaatcg tttatgtact cttttatttc
     6301 tcaaatatca aagatgcaca tacgattgca aaacgcatta acaatggaat tccagttcca
     6361 cgcacactca aagacatgat caaagggatt tatgaaaatg gcttccctta cctcttgatc
     6421 attccatctt atgttgccat gaccttcgcg attatcttcc cagttatcgt aaccttgatg
     6481 atcgccttta ccaactacga cttccaacac ttgccaccaa acaagttgtt ggactgggtt
     6541 ggtttgacca actttacaaa catttggagc ttgagtacct tccgttctgc ctttggttct
     6601 gttctttctt ggactatcat ttgggctttg gcagcttcta ctttacaaat cgtaattggt
     6661 atcttcacag ctatcattgc caaccaacca tttatcaaag gaaaacgtat ctttggtgtt
     6721 attttccttc ttccttgggc tgtcccagcc ttcatcacta tcttgacatt ctcaaacatg
     6781 tttaacgata gtgtcggtgc tatcaacact caagtattgc caatcttggc taaattcctt
     6841 cctttccttg atggagctct tattccttgg aaaacagacc caacttggac taagattgcc
     6901 ttgattatga tgcaaggttg gctcggattc ccatacatct acgttttgac tttgggtatc
     6961 ttgcaatcta ttcctaacga cctttacgaa gcagcttata ttgacggtgc caacgcttgg
     7021 caaaaattcc gcaacatcac tttcccaatg attttggctg ttgcggcacc tactttgatt
     7081 agccaataca ccttcaactt taacaacttc tctatcatgt acctcttcaa tggtggagga
     7141 cctggtagtg tcggaggtgg agctggttca accgatatct tgatctcatg gatctaccgt
     7201 ttgacaacag gtacatctcc tcaatactca atggcggcag ctgttacctt gattatctct
     7261 atcattgtca tctcaatctc tatgatcgca ttcaagaaac tacacgcatt tgatatggag
     7321 gacgtctaag atgaataact caattaaact caaacgtaga ctgactcaaa gccttactta
     7381 cctttacctg attggtctat caattgtaat tatctatcca ctgttgatta ccattatgtc
     7441 agcctttaaa gcaggtaacg tctcagcctt taaactagat actaatatcg acctcaattt
     7501 tgataacttt aaaggcctct tcactgaaac cttgtacggt acttggtacc tcaacacttt
     7561 gattatcgcc ttaattacca tggctgttca aacaagtatc atcgtacttg ctggttatgc
     7621 ttacagccgt tacaacttct tggctcgtaa acaaagtttg gtcttcttct tgatcatcca
     7681 aatggtgcca actatggccg ctttgacagc cttcttcgtt atggcgctta tgttgaacgc
     7741 ccttaaccac aactggttcc tcatcttcct ctacgttggt ggtggtatcc cgatgaatgc
     7801 ttggctcatg aaaggctact tcgatacagt gccaatgtct ttagacgaat ctgcaaaact
     7861 agacggtgca ggacacttcc gccgcttctg gcaaattgtt ctaccacttg ttcgcccaat
     7921 ggttgccgta caagctctct gggccttcat gggacctttc ggggactaca tcctctctag
     7981 tttcttgctt cgtgagaaag aatactttac tgttgccgta ggtctccaaa ccttcgttaa
     8041 caatgcgaaa aacttgaaga ttgcctactt ctcagcaggt gctatcctca tcgcccttcc
     8101 aatctgtatt ctcttcttct tcctacaaaa gaactttgtt tcaggactta caagtggtgg
     8161 cgacaaggga taatttatcc ccgccaccct ttttcatttt atactcttcg aaaatctctt
     8221 caaaccacgt cagctttatc tccaacctca aagttgtgct ttgagcaacc tgtggctagt
     8281 ttgcactttg attttcattg attattagca attgtcactg taaataatat ccttgtagca
     8341 agcaattttt ctcctagact tgaaataaag cgcatttctc tatataataa tactcatata
     8401 gaaaacacct tttagaaaga tacctatgct tccatatcca ttttcctatt tttcaagtat
     8461 tttggggttt cgtaagcccc tgtccaaacg tttcgggctc aactggtttc aacttctctt
     8521 taccagtatc ttccttatca gcttgtctat ggtacccatt gctatccaaa acagctccca
     8581 ggagacctat ccgctagaaa cttttatcga taatgtctat gaacctctga caaatgaggt
     8641 tgtccaggat ctctctgaac atgctacaat tgtcgatggc acattaactt atgctggaac
     8701 agttagtcaa gcctcttctg ttgtgattgg tccaagtcaa atcaaggaat tacctaagaa
     8761 cttgcaactg catttcgata caaatgagct agtcatcagc aaggaaaaca aggaactgac
     8821 ccgcatctct taccgagcca ttcagactga gagtttcaaa agcaaagaca gcttgaccca
     8881 agcaatttct aaagactggt accaacaaaa tcgtgtctat atcagcctct tcctagttct
     8941 cggtgcgagc ttcctctttg gtttgaattt ctttatcgtc tctctaggag ctagtcttct
     9001 cctttatatc actaagaaat cacgcctctt ttcatttaga acctttaaag agtgctatca
     9061 ctttatcttg aactgtttag gattgccgac tctgattaca cttattttgg gattatttgg
     9121 ccaaaatatg acaaccctga ttactgtaca aaatattctt tttgttctgt atctggtcac
     9181 tatcttttat aaaacacatt tccgtgatcc aaattaccat aaataggaga tttttatgcc
     9241 cgttacgatt aaagacgtgg ccaaggctgc tggtgtttcg ccttcaaccg taacccgtgt
     9301 tattcaaaat aaatcaacca ttagcgacga aacaaaaaaa cgcgttcgca aagctatgaa
     9361 ggaactcaac taccacccaa acctcaacgc tcgtagcttg gtaagcagct atactcaggt
     9421 tatcggatta gttcttcctg atgactcaga cgccttctac cagaatcctt tctttccatc
     9481 ggttctacgt ggcatctctc aagtcgcatc tgaaaaccac tatgccattc agatagcaac
     9541 agggaaagat gagaaggagc gtctcaacgc tatttcacaa atggtctacg gcaagcgtgt
     9601 agatgggcta atctttctct atgcccaaga agaagaccct ctcgtaaaac tcgtcgcaga
     9661 agaacagttc cccttcctta tcttaggtaa atctctatct cctttcatcc cacttgtcga
     9721 caacgacaat gttcaagctg gttttgatgc gactgaatat ttcatcaaaa aaggctgcaa
     9781 acgcattgcc tttatcggag gaagtaaaaa gctcttcgtg accaaagacc gtttaacagg
     9841 ctatgaacag gcgcttaaac attacaaact taccactgac aacaatcgca tctactttgc
     9901 cgacgagttt ctggaagaaa agggctataa atttagcaag cgattattca agcacgatcc
     9961 acaaattgat gctatcatca caaccgatag cctcctagct gaaggtgttt gtaactatat
    10021 tgccaaacac cagctggatg tccctgttct cagctttgac tcggttaatc ccaagctcaa
    10081 cttggcagcc tatgtcgata tcaatagttt agagcttggt cgtgtttccc ttgaaactat
    10141 tctccagatt attaatgata ataaaaacaa taaacaaatt tgttaccgtc aattgatcgc
    10201 ccacaaaatt atcgaaaaat aagagactgg gcaaaaagtc gttaaaagca aaaacgcata
    10261 ctatcaggta ttgaaaaaac ttgatactat gcgttttatt gtgggaagat ttacttcctt
    10321 ttctactgaa attgagtctt ttcccaagat ctttttatac tcaatgaaaa tcaaagtgca
    10381 aactaggaag ctagccgcag gttgctcaaa acactgtttt gaggttgtag atgaaactga
    10441 cgaagtcagc tcaaaacatg gttttgaggt tgcagataga actgacgaag tcagtaacat
    10501 atatacggca aggtgaagct gacgtggttt gaagagattt tcgaagagta ttaatcacta
    10561 attatctatc tcaacaaatc ttcctagaat atgaacattt tccgagacag agacaaagga
    10621 gcttggatcc acttgtgtca taatctgttt aaattcatta aactctgcac gtgtaatgac
    10681 agtgattaaa actgcctttc tctcgtgatt ataggttcct tctgcatcgt ggatcatggt
    10741 tgctccgcgg tgcaattttt tatggatttt ttcaattacc ttctctggat gatttgtcac
    10801 aatcatggcc tgcatacgct tttgcttagt aaagactgcg tctgtcacac ggctagagac
    10861 aaagatggta atcatagaat aaagagcgta tttccaacca aaggttaaac ctgctatcag
    10921 catgatagtt ccatttacca agaaagaaat actaccgaca ttcttacccg ttttcttgcg
    10981 aatagtcagg ctgacgatat ccgtcccacc actggagata ttgtttcgaa gagcaaaacc
    11041 aatccccaaa cccataacaa cacccccaaa aagggaattg ataatgggat cctccgtcaa
    11101 ggttgccaca gggacaaact ggataaagaa ggaactcata gataccgtga taaaggtaaa
    11161 gacggtgaac ttatggccaa tctgatacca agctaagacc atcaaaggga agttaatggc
    11221 gtagaagctt agcgaaatcg gaatatgaaa accaaaccag tgattactca aggcagagat
    11281 aatctgtgcc agacctgttg caccactcga atacacatgc cctggttgga aaaagaaatt
    11341 aactgctact gctgataaaa aaccatagac cagagaggcc gaaatcttct catcatactt
    11401 ttctcgagag atactttgta agacacgtaa aatttttatc tgataagcaa agcggcgcag
    11461 ataatagcgc catcgcttaa ttcgttttgc ttgtttcatc ttcttctact tgtaagctga
    11521 gttcctctag ttgtttgaga gcgactgttg atggagcttg tgtcattggg tcagttgcct
    11581 tgttgttctt aggaaaggca atgacttcac ggatattttc ttctccagca agcaacatga
    11641 caaaacggtc aagcccgata gccaaaccac cgtgtggtgg gaaaccatag tccatggctt
    11701 caagaaggaa accaaactgg tcattggctt cttcagttga gaaaccaaga gccttgaaca
    11761 tgcgttcttg aaggtctttt tggttgatac gaaggctacc accaccaagc tcataaccgt
    11821 tcaagacgat atcgtaagca atggcacgaa ccttagccaa atcaccttct aattcgtgag
    11881 cagtctcttc ctgtggaagg gtgaaaggat ggtgggcgct catgtagcgg ccttcttctt
    11941 cagaccattc aaacatcggc cagtcaacca cccaaaggaa gttgaactta tcattatcaa
    12001 tcaagccaag ctctttagca atacgtccac gaagggcacc cagtgttgca ttagccactt
    12061 caagcgtatc cgccacaaag agaaccaagt ccttatcttc aagagcaagc gctgttgtca
    12121 attcttcttg gataccagtc aagaacttgg caactggtcc gtttaattct ccatcaacca
    12181 ccttgaccca agcaagacct ttggcaccat actgtttggc tacttccgtc atcttgtcga
    12241 tgtctttacg tgaatagttg tccgcagctc ctttgaccac aatcgctttt acagcaggtg
    12301 cttctgaaaa gactttaaag tctacacctt tgaccacttc tgtcaagtcc tgaagcaaca
    12361 tgtcaaaacg agtatctggc ttgtcagaac cgtaaagagc catagcatca tcgtatttca
    12421 tacgagggaa cggtagcgtt acttcgatgc cttttgtttc cttcatcacg cgcgcgatca
    12481 agccttctgt aatatcttgg atttcttgct cagtaaggaa ggacgtttcc aagtcgacct
    12541 gagtaaattc aggctggcgg tctccacgca agtcctcgtc acggaaacat ttaacgattt
    12601 ggtagtaacg gtcaaaacca gcattcatca agagctgttt cgtgatttgt ggactttgag
    12661 gaagagcgta aaaatgcccc ttattaacac gagacggtac taaataatca cgcgcccctt
    12721 caggcgttga cttagaaagg aatggtgtct ccacgtcgat aaactccaac tcatccaaat
    12781 agttgcggat agagtgggtc accttggcac gaagtttaag attttccaac atttctggac
    12841 gacgaaggtc aaggtaacgg taacgcaaac gtgtatcgtc atttgcctca atgccatcct
    12901 taatctcaaa tggtgttgtc ttagctgtgt taagcacaat aagagctgtc acgtttaact
    12961 caaccgcacc agttggcaac ttatcattgg cttgctcacg cgcagcgacc tgaccagtca
    13021 cctcaataac aaattcgcta cgaaggcttt cagctgttgc cataacctct gcagatactt
    13081 tttcagggtt gataaccaac tgcatgattc cttcacggtc acgaagatcg ataaagatca
    13141 aaccaccaag gtcacgacga cggccaaccc atcctttcaa ggttatttct tgtccgatgt
    13201 gttcctcacg aacacgacca gcatacatac tacgtttcat tatttctctc ctcttttatt
    13261 ctgttactat tttaccataa aagcgcaggc tcttcatgaa aatcatcaga aaagtttgcc
    13321 agtctttaaa agtcaggtga aagccctaaa aattagcgct aatactcttc gaaaatctct
    13381 tcaaaccacg tcagcgtcgc cttaccgtag tacggttact gacttcgtca gtttcatcta
    13441 caacctcaaa accatgtttt gagctgactt cgtcagttct atccacaacc tcaaaacagt
    13501 gttttgagca acctgcggct agcttcctag tttgctcttt gattttcatt gagtataata
    13561 caaaaatccg atgaacttca ccggactctt ttattttgaa tttttgcctg ctttacgctt
    13621 ttcagcgatt tcggctgcct ttcgaggcaa gacaatttcc gttatgtaag ccgtcccaaa
    13681 acgcagtaca cctgcaatag gagcaaagac aactgctaga tagttataga agaaatcgcc
    13741 tttgaaggca taagctagcg ctccaatgat gaaaaataga acgactgcct gaatcactgc
    13801 taataaaatt actcgtttca tgtgacctcc tgactctatt atagcatgag aatcatcaaa
    13861 aagccgacta aattattcaa agcgtgaaga gaaatactgt agaccagacc ttttctgcta
    13921 acgtaagcca aacccaaact aaaaccaagg ctaaaataga caaaaaattg ttgcacatca
    13981 cctggaaaat gaatcaaggc aaatagaaga ctagatacca gaagaaaaat cagggttcgt
    14041 ttactattgt cctgcttagg aaagagatag cgtgctaaca tccctctaaa aacaatctct
    14101 tccgtcaaag gagcaaaaat aaccacagca aagaatgaga aaagtggttg agacaaggtc
    14161 aagtctgtcg ctatttgctg atttactgaa ggatcatctg gcaagaagaa ttgaacgacc
    14221 agagataaga accaaaccaa ggcaggaagc caaataaatc ggttaaagcc gctcttctca
    14281 atataaacag gagctttctg ataccatttg taaatgccgt acacatatac tccagccaag
    14341 accacataga gtagagtaac agcatagggt gaagcgccta aagcaagcga cgcagtcgcg
    14401 agcccctgaa taaagccata gataaagaaa aaggatagaa gggctagaag aatccagcca
    14461 aggtttttaa gtaatttcat agataactcc tttatttgaa ataacgtttt accataggta
    14521 actgcatcac attgatataa acatggatgg ctcctacaag caagaaagct agtaactgaa
    14581 tctctcctgt caagaaagaa atgataataa gaaaaatata taaggctggt aagacatatt
    14641 ggtgtaattg gaataaaatt cgaaaactct gttccaaatt agcctgacgc tccccttcat
    14701 cataagaatt tatatagttc aagacatcct ttggtgtagc gaaaaattcc aaatcaaact
    14761 gacgaacaat cgcaatggtt ttaaaaagag atttttgagc gactaagaat accacaaaga
    14821 gtaagaaaga aaggaaaaat gtttgagggt ttgtatgcaa tataatcacc tcacttaatg
    14881 aaataaaaat agccaatgga atcgctacac ctgtaatatt aaaagcaatg gttccaaact
    14941 caagattccg atacatttgc acataatagg tttcattcag atcgtcatcc atttcctctt
    15001 gatacaagga atgaaatttt ctgcttttct ttaagaaatt gaaagtcaaa aacatactaa
    15061 tgaaacctat cagtaaacaa atagctgata tccatggcat caaggctttt acatctaaaa
    15121 taatttcgtg ggattcgaca cgtgccttaa acatccctac aaacatgccc aagacccccc
    15181 caaagacaat agacatcaaa aataacaatc tacgtttctt tttcatattc attctccttt
    15241 ttcacttgct agatttttgg atttcttttc aatccattca attactggga tgagagcaaa
    15301 gtagacccaa acaaattggt cgctttgata gggattaaac cagcttaggt ccatcccaat
    15361 cagtagaaat acgctgacta ataaagctat gaccactaca taataaatca ctttatactt
    15421 gttcatcact cgtcctcctc caaacgaaat accgattcga ctgtttcgtt gaaaatttga
    15481 gatattttca gggcaatgat aatggatggg gtgtactcat cccgttctag taggctaatg
    15541 gtctgtctgg aaacccctgc cagtttggct aggtcagttt gattgagacc atcgcgagct
    15601 cgaagctctt ttagacgatt ttttagttgc acgttacaca cctactctcc gtcaaattca
    15661 acggtttgga tatcttcaat acgttgcaac ttgaattttt cttttcccgt attatctaca
    15721 cgtcgtagct ttacccattc ctcatcaaca tccacaactt cccagttatc tggcccaata
    15781 tacactcccg ttataattgg tttctttcca atcatttctt gcaataatct cgacatttct
    15841 gcgtttcctt tctcttttcg ctcaagtttt ttgattttat tctctagttt cttgattttt
    15901 ttagaattat tagaataaaa gaaaataata aatagtataa atactagtac ccacatcata
    15961 gctcctttct tcttttctct taacttgctt acattgtaac acatcttttt ctttttgaca
    16021 agtatagctg tcaaaaagtt tatgattttt gtcattttgc aaaagaaaaa ggtcaggagt
    16081 aagttcctga ccactttatc tatcattaat actcttctaa aatctcttca aaccacgtca
    16141 gtttcatcta caacctcaaa accatgtttt gagtaacctg cggctagctt cctagtttgc
    16201 tctttgattt tcattgagta taaaatccta gtttttcaaa gatttctgag aagttttggc
    16261 tgattgtctc aagtgacact tgcacttctt ctcgggtttg gttgttcttg actgtcactt
    16321 gtctgctttc gacttcgctc tctcctaggg tgatgagggt cttagccgca aagacatcgg
    16381 ctgacttgaa ctgagctttg agcttacggt tgaggtaatc acgctctgct ttgaaacctt
    16441 gttggcgaag agcttggact agttctaggg ctttgacatt tgctccatca cccaagactg
    16501 cgatatagac atctagggca ttttcgatag ggagggccac gccttgtttt tcaaggatga
    16561 gaagcaggcg ctctacacca agcccaaaac caaatccagc agtttcaggg cctccaaagt
    16621 aagcaaccaa accatcgtag cgaccacccg cacagactgt caagtcattg ccctcaatct
    16681 ctgtgataaa ctcgaaaatg gtgtggttgt agtagtccag accacgcacc atattggtat
    16741 cgatgatgta atctactcca agattttcca acatctgacg cacagcatca aaatgagttt
    16801 ggctttcttc atcaagaaag tccaagatag acggcgcatt ctctactgcc accttgtctt
    16861 ctttttcctt agagtccaag acacgaagag gattttcctc caagcgacgt tggctatcct
    16921 tagacaaggt ctccttgagc ggtgtcaaat agtcaatcaa ggcttggcgg taggctgcac
    16981 ggctctcagg atttccaaga gtgttgaggt gcaatttgac accttgaata ccgatttcct
    17041 tcaaaaaatg ggctgccata gcgattgttt ccacatcgat agctggattg ctagagccaa
    17101 aacactcaac accaatctgg tggaattggc gcaagcgccc tgcctgtgga cgctcataac
    17161 ggaacatagg tcccatatag tagaacttgc ttggcttttg cacttctggg gcgaagagtt
    17221 tattttccac ataggaacgg acaacgggcg cagttccttc tggacggagg gtaatatgac
    17281 ggtcaccctt gtcataaaaa tcgtacattt ccttggttac gatatccgtt gtatctccga
    17341 cagagcgact gataacctcg taatgctcga aaataggcgt acgcacttct gcgtagttgt
    17401 agcgtttgaa aatttcacgg gcaaagccct caacgtactg ccacttggca gattcagcag
    17461 gtaaaatatc ctgcgttcct tttggttttt gtaatttcat agggaatcct ctttaaactt
    17521 aatagtctta ttttaccata aatagaggga ttaaaacagt gagaaaaaaa ttaggattta
    17581 gatatcattt ttgagattaa gaattgtcaa aaaaatagct agcaaggaaa aaccaacaaa
    17641 tagcatccaa gtcaactgca tgttccatat ggctactagt gaaaaacaag ctgttcccac
    17701 aggtatggat aaggtaaaca atagaccgaa aaaattacta gtacgagcta gaacctctgg
    17761 agctagattt ttcatgagca tggcactaat ctttggttga actttaccag acacatacag
    17821 agtaaagaag agaaatagca aaccaagcac gacttgattg aataaattag ccaaaccaac
    17881 tagactaagt cctacggtcg cccacatcat caatctaggc aaggactgct tcccaaaata
    17941 atcattgccc gtaaggctac tgatgatgat tgctactaaa acacagaatt gattgataaa
    18001 tagtgcctct gtataagaaa aattcaagag agaatggctc aaaaagaaga tattataaat
    18061 tccacccaaa gcgccaccca aggaattaat aagcaagaca gcaaagagca taaaaccaaa
    18121 gtttttctgt ccacttttaa gaaaaacgag acgtaaattt cggtaaattg ttaggaactg
    18181 gtctttgata gaaagcttct cattttttaa gttttcacca tcagcagatg acattgacag
    18241 gctcaatttg ctttttccta aaaagaggat agtggctgat acgaggaaaa agcaagcatt
    18301 aattcccgca acgagggaaa aattgttgac cgatagagct aagagccaga ctccgaaagc
    18361 ttgaccacca atagctgaaa tataggtgat gaactgtgaa aaagaataag cctccatcag
    18421 atcatcttca gctacttttt ccttaataag aggcatacgc aggccacctg caaaatcact
    18481 gatgatatca ctaatgacat tgatcaaaca caggctagaa aaggcaaaga gactagcttg
    18541 ctgaacaact agggctgcta gaaaaaatag aaccgcctga aacaaaccgc tatagaccat
    18601 ccatttgacc ttgtccctcg tgtaatctgc ccgaatccct gcaaaaactg taaagaaggt
    18661 cggaagaatc atgacaatat tcgccatagc aacagcaaaa gatgcttgtg acaaggtcga
    18721 tgcatagacg ataaagacca ggttgaaaat cgaagcacca aaagcattga agaagcgtga
    18781 caaagtcaat aggcgataag cttgatttct aaacaatagt ttcatagata atctccctcc
    18841 ttgttctaag ttctacatca agaatagctt tagtatagca cttatgaatt tgcgaaacga
    18901 ttcttttgaa tatatgcaac aaataaaatg agcaaaaaac gatagaactt ttgtaatgac
    18961 ctgagaaagg gcaacagttc tatcgcttca aattttttct tagtttgcag atattcaaca
    19021 ttcggtcgta tttctatagt attcggcaga tttattacag ccaagcatct caaaaatacg
    19081 gacagcatcc tccatctttt tctggccttc cttgactcta ccttgcttgc tatcaaggag
    19141 accttctgcc cacagataaa caattcggaa ataggtctca ttttccttgt agaaatgctc
    19201 ttcgataaca cgtttaaaat aataggcatt ggtaaatttt tcacactcaa tactagctaa
    19261 aaagccattc aatagtatag tatgaaaaaa gtttcgatta ccagacattt ccattagaaa
    19321 atcagattta cgtaccattt ctcgtacata tctagtaaaa agagaaacag ataaaaatgg
    19381 agaactgact gaaaataaat tgagttcata gattccccag atctcggtag aaaacaaata
    19441 atcatgaagg acttttcctt cctctgctgt taactctacc ctttcatcta tgctcttcat
    19501 ataagacttg atcataatgg catttagaat atgtttctgt ttgttgtgag aatgggcatg
    19561 cttttgatac tccctgcgat ataagtcctc aagaggtgct atattctttg gttccaagac
    19621 atctgtaatt tcttttctca actcagaatc tgtatcatac tggaaacctc tcgccagaaa
    19681 gaggatctcc tccacactgg cagatatatt ttccagagca aatagaaact tttccaccga
    19741 aagctcactc tgacctgttt caaaacggga caacatagac ggcgaaaatt gtcctccggt
    19801 tgcttgtctc agtgagatat ttcttgattc tcgtaattgt ctaaagactt ttccaatctg
    19861 ctccatagac ttccccttga ttccgtattt tcttcatttt atcatatttt tcagaaaatt
    19921 catcaaaaac ttgccaaatt gtcagaatta tgagaaaata gaggatattt atcacgtgga
    19981 gggactgcta tgagagacga tatcaaaatc aatgaccgtg ctttggcctt gcaagaccaa
    20041 atcatcgaaa aactagagaa agtttttgat acagatgtgg aattggatgt ttacaatcta
    20101 ggtctgattt atgaaatcaa tctggatgaa acggggctct gcaagattgt catgaccttc
    20161 accgatactg cctgtgattg cgccgaaagc ctgcctattg aaatcgtggc aggtctgaaa
    20221 caaatcgagg gtatcaaaga tatcaaggtt gaagttacct ggtcgcctgc ttggaaaatc
    20281 acacgaatca gtcgctatgg ccgtattgcc cttggattac cacctcgtta agcaggccaa
    20341 tcacttttaa agatgaaaaa agcaagccaa aaatggcttg ctttttgata ctcaatgaaa
    20401 atcaaagggc aaactagaaa actagccgca ggttgctcaa aacactgttt tgaagttatg
    20461 gatagaactg acgaagtcag ctcaaaatac tgttttgaag ttatggatag aactgacgaa
    20521 gtcagctcaa aatactgttt tgaggttgtg gatagaactg acgaagtcag ctcaaaatac
    20581 tgttttgagg ttgtggatag aactgacgaa gtcagtaacc atacctacgg caaggcgacg
    20641 ttgacgtgat ttgaagagat tttcgagtat gagtttattt tttacctgac ttgtccatat
    20701 tccagaagtc tgtcacggct ccgcgtgaag cagatgatac gatgtgggca tatttaccga
    20761 ggacaccacg gctgtaaagt ggtggcaagg ttgtttctgc cttgcgtttt tcaagttctt
    20821 cttcggatac ggccatggaa atttctttgg tatcttggtc aaccgtaacg atatcgccgg
    20881 tacggagata ggcaattggt ccaccatcct gagcttcagg agcgatatgt ccaacaacca
    20941 gaccataagt accaccagag aaacgtccgt ccgtcaagag ggccacctta tctccctgac
    21001 ctttaccaac aatcattgaa gaaagtgaca gcatctcagg cataccagga ccacctttag
    21061 gtccaacaaa acgaacaacg actacatcgc catcaacgat ttcatctgtc agaacggcct
    21121 gaatcgcatc ttcttctgag tcaaagacct tagctggccc aacgtgacga cgcactttaa
    21181 cacctgatac cttggcaact gcaccgtcag gagcaaggtt cccgttcaag atgataagcg
    21241 gaccatccgc acgttttgga ttttcaagtg gcatgataac tttttggcct ggagtcaagt
    21301 ctgcaaagtc agccaagttt tcagctacag tcttaccagt acatgtgatg cgatctccgt
    21361 gaaggaaacc atttgccaac aagtacttca taaccgcagg gacaccaccg acttcgtaga
    21421 ggtcttggaa gacatactga ccagatggtt tcaagtcggc caagtgaggc acacgttctt
    21481 gaatcgtatt gaagtcctca agtgacaagt caacatttgc ggcatgggca atggcgagca
    21541 agtgaagagt ggcgtttgta gaaccaccga gagccatcgt tacagtaata gcatcttcaa
    21601 aggcttcacg agtcaagata tctgatggtt tgagaccaag ttccaacatc ttaacaacag
    21661 cacgtcctgc tgcttcgata tcttctttct tatcagctga ttcagctggg tgagaggatg
    21721 accctggcaa actcatccct agaacttcga tagcagttgc catggtatta gcagtataca
    21781 taccaccaca gccaccaggg ccagggcagg cattacattc aagacgtttc acgtcctcag
    21841 ctgtcatgtc accgtggttc cattttccga taccttcaaa gacagaaacc aagtcgatat
    21901 ctttaccatc aagatttccc ggtgcaatag ttccaccata ggcgaaaata gctgggatat
    21961 ccatattagc aatagcaatc atagatccag gcatgttctt gtcacagcca ccgatagcga
    22021 cgaaggcatc cacgttgtga ccactcatag ccgcctcgat ggagtccgcg atgatgtcac
    22081 gagatgttag agagaaacgc ataccaggcg ttcccatagc gatcccgtcc gctacggtaa
    22141 tggttccaaa ctgtacaggc caagcgcctg cagatttgac accttcttta gccagtttcc
    22201 cgaaatcatg caagtgaatg ttacatggtg tattttccgc ccaagtcgaa atcactccca
    22261 caatcgatgt ttcaaagtcc ttatctgtca taccagtcgc acgaagcata gcacggttag
    22321 gtgatttaac catgctgtca tagatgctac tgcggtgacg tttatctaat tcagtcatct
    22381 tatccctccc atttcagttt ttactattat agcacaattt aaaggcaatg aacagaataa
    22441 aattcttgaa ttttcagaaa attctatacg catgtgaaat atttaaaatt aaaaacaaca
    22501 aagcggatta gtgcactttc tgatgaccag aatatgcttt ttaatccgct ttctttaaat
    22561 aacgtactgt aatttttaca gaaattcttt caaataagtg tatttaacat ctatcttgca
    22621 ttataaattt ctagaacctt ctcttttata ttcgattcac tcaaaccata ctcattaaga
    22681 agataatcca ttttccctac ttgaccaaat ctttcttgaa cacccatccg atgaattttt
    22741 gttattccat catcagagaa taattcacat aaagcactgc caattccacc tatctgattg
    22801 tggttttcta cagtaaatat agtttttcca cttaacattg tttttatctg ttctggtatc
    22861 ggtttgattc taaataaatc tatcacacct actgaataac ctaatttaga cagttcatct
    22921 gcaactcgaa tacttggagc aaccattatg ccagaagcaa cgattacaag atcttcacca
    22981 tgtcttaact caatgtagcc tttagaaaaa tcttctccac cttgatatac agcctctgga
    23041 gcttttctaa ttgttcgaat atattttagt ccttttaagt ctaatgtctg attcaatatt
    23101 tcacgaaatt ggatatcatc agttgcttcg aaaatgattg atttaggaat taaacgtaac
    23161 aagccaattt cttcaaatgg catatgtgtc ccaccattca tttctgcagt tactcctgca
    23221 tctgatccaa tcacagtggc atccaattgt gcgtatccaa gagaaataaa taattgatca
    23281 aatacccttc gtgaagaaaa aggaccaaat gtatgaagat aaggtctaaa cccctgaata
    23341 gacaagcctg ctgcaaggcc gaccatttct gcttccataa tcccaacatt cacataacgg
    23401 tctccaaagt ccttttcaag attatgagta gccatcgaac ttgacaaatc ggcttctaag
    23461 actactatat cagaatcact ttgattagcc tctaaaagga agtctctata tacatgccgt
    23521 aattctttcg tacttctcat cattctgttt cctccaattc ctgacttaat ctttctacaa
    23581 ctgaagttaa catttgtttc tcctctacag tagggcgaag atgatgattg gatttcattt
    23641 cttccagctc ttgaacccct tgacctttaa tagtatctaa tacaatgcac ttaggtgatg
    23701 aattatttga ctgttttaat tggacaatcc cttcataaat ttctctaata tctgaaccct
    23761 tgaccctaat ggattcaaat ccaaatgctg aaaatttttc tacgaaatca cctggattac
    23821 aaatatcctt tgtaaaacca tctaattgtt ttttgttatc atcaacaaat acaattaagt
    23881 tggataactg ttgatgagaa gcaaactgta tagcctccca acattgtccc tcatttaact
    23941 caccatctcc aacaatagca taagtataaa agggactctt tcttattctc tgaccatatg
    24001 caagtccagt tgcaacacta attccttgtc ctaaagagcc cgttgtcata tctatgcctg
    24061 gcgttagatt tctatcagga tgagacggta atttggttcc atttgtattt aaagaatata
    24121 ggaattcttt gtcaaagaaa ccattcaaat agagtgtact gtatagagct ggtcctccat
    24181 gaccttttga taatatgaaa taatctctat ctcgtgctgc aaatatttct ggagtcattg
    24241 gcattatttc accataaagc actgctaaaa cttctacgat agacagactt cctccgtaat
    24301 gtccgaatcc aagatgattc aatgttctaa gagtatttaa tcggatgtta gtcgcaaatt
    24361 ttcttaactc atcttctcta tttttactta aaatcatccc ttattcctcc tttgcagatg
    24421 gctttttaat aaaggatact ccaaacataa ctgctaaaat aagaacaaga ccaatcacaa
    24481 tgcctgcttg tgagccaaat tgatttaaca ttcctaaaat aattcctgat agaccaaaat
    24541 ctgcatctga gaaagttgat ccttggaaac cgagtcctcc caaaactggc attaaaaaga
    24601 ctgggagaaa actgattaaa ataccttgta aaaatgctcc aatagtggct ccacgaacac
    24661 caccagatgc attcccaata acacctgcag tcgctccaca gaagaaatga ggcacaacgc
    24721 ctggtaagat aacaaccgtt cctgaagcaa tcataattgc catacttact aaaccaccaa
    24781 taaaactaga gataaatcca attagaactg cattaggtgc ataagtataa acaatcggac
    24841 aatccaaagc aggttttgaa ttaggtacaa gacgctctga aataccttta aaggctggaa
    24901 caatttcgcc caaaataagg cgaacacctg ctaaaataac aaatacccct gctgcaaatt
    24961 gacctgctaa ttgtaaagca taaactagac cacttgtacc actactgatt tctttttcta
    25021 tatattctga ccctgcaaag atagctacaa taatgtaaat aactgccata gataaagtga
    25081 tactaacagt actatcacgt aaaaaagcta aactctttgg aaatttaatg tcctctgttg
    25141 attttgattt gtcaccgata aggctaccag taaaaccact caaccaatat cccaaagaac
    25201 tgaaatgacc taaagccacc ttgtcatttc cagttaattg aaccatatat ttttgcacaa
    25261 atgctgggga aatactcata ataataccga gtgctaatcc tcctagtaag atgagaggca
    25321 agctagtaaa gccagcaact gataaaatga ccgcaatcat acatgccata tatagagtgt
    25381 ggtgccctgt taaaaaaata tatttaaatc gagtaaaacg agcgattaag atattgaaca
    25441 ccattcctgc aaacataatc attgcagtag ctgagccata tgttgttaaa gctacagcta
    25501 caattgcttc attattcggc acaacgccag ataaatgaaa agcatgctca aacatggtac
    25561 caaatggatt taaagaattt tgtacaattc ctgcaccacc agatacaact aagaaaccaa
    25621 caaaggtctt aattccacct ttaataatat caggtaattt cttcttctga agaactaatc
    25681 ctaaaattgc aattaaagct actaaaatag ctggtgtact aacaatatcc aatatgaact
    25741 tcatcatgac gctagcctcc tatataagtc ctttttcttc acaaagttta gtaattaatt
    25801 ctcgtagttc atccatatca ataatactat ttaagatacg aacatctcca agatgactag
    25861 ctgaatcagc tagatcacga ccaacaatcc aaatatcagc tgcatttgga tctgctccac
    25921 ctaaatcata atgttcaact tctacatccg aaacattcaa atcactcaat acagattcaa
    25981 tattcatctg taccataaaa cttgaaccta atcctgaacc acaagctgta ccaattttta
    26041 acattatcta atcctcctgt ttaattatca ttttaatgtc atcatagttt tttgatgata
    26101 ttaaagtttg aacatgattt ttatctctta aaattgttgt taaatgtgac aaagccttta
    26161 aatgactctc attatcaatg gctgcaatac aaatcaacaa tcttacctct tgttctggat
    26221 tatccaataa ataaatcggt tcttccaaaa ctaacattga cattcctatt tcattcacac
    26281 cttcatctgg ccgagcgtga ggaattgcta ctcccttccc taaattaata aaaggcccaa
    26341 actcttctac tttttgaatc attgcctcag ggtagttctc agttatctta tcttgatcca
    26401 aaagcggttt agctgctaaa cgaatcgcct ccttccatcc taatttttgc gaactaacct
    26461 gataggtttc tttggtaatg agttgttcta gcactggtac aatttccttt ctatcatttt
    26521 tttggtaaag ataattcttt aacgccaatc ttaattccaa ttcttgtgta ataattccat
    26581 atcttttgac aatattcaga atttgttcaa tctcaaaatc cccatactct aaattcggaa
    26641 aatcttttaa cactagttct actagttgta ttgcttgctc ttcagtcatc ataaccgaaa
    26701 ctagataatt tggcttttct gtctccacct ttatggtaga aaaaaccata tcatagtcac
    26761 tactagcttt cacctgtaaa tcatcaatct ttgaggttcc tataaactca atttgaggaa
    26821 ataatgctaa tagattctct tttaacatca atgaagaact aacaccatta ggacaaatga
    26881 ttgctgcttt ataccatttt tgaggcaaag tatctgcttt ctttaaataa cctccgaaat
    26941 ggataacaaa atatgctgtt tcactatcag gtatgggatt gtcaatagcg tccatcaagg
    27001 gcatcaaaga atctttgact aattcaaata aatcaggata atattcttta acatgcaata
    27061 catattcatt tgaactaggt aggccgaact ttaatctata gtaagccggt ataaggtggc
    27121 ggcgaagatt ttctctcaat ccttcccttt gtttaaaatg taacaaagaa atatcttcca
    27181 ttctacttat aatagcctct gttaattgat taaagtaaac cggagcaaca tctacttcac
    27241 cttcaaagca acttgataat aaaacggtga tatagcgata atcatcctca gaaaacaccg
    27301 tatctataat tcccaaatca accactgtat ccaataaaat agtggttata tcttgaataa
    27361 caggagatac taatgtctct gaaagacata ctctttcaac atccctttga tacctacaca
    27421 gaatgaatac taaaccgaaa aggtaaactt ttaattgatt aacaataggt actagctgta
    27481 gcttctcata ataatcttta actacctgat ttatcaaatc ataagttaat gaataccccc
    27541 aactggataa aacataatcc aaaccccaaa tccctatgga ggattccagc aactcactaa
    27601 ccatttgaaa agctaagcgg tgcttattcc actctgaacc gtgtaaagta taaccttttg
    27661 ctctactgta ccctagctcc aaatcattat ctaacataat ctttcttaat gattgaatat
    27721 cagataaggt tgtattctta cttactttca aaaagtcttg gtaatgatta ttcgatataa
    27781 aatctaatcg gcaaaaagtg taaagataga ttaaagctaa gcgagtcgac tttggtaaaa
    27841 ccaattcatc cgacttaata atatctgtca aagactgctt cgtacgattt gataaactat
    27901 agcgaccttg ttttttatcc agcactatcc ctttattagc tagataaggc actaaataat
    27961 ctattccttc tttgacttcc tttataggta agctcacctt aacagataat tcatataatg
    28021 atagctcaca atgatccatc aaagtcatca aaataactag tgctctataa tcaaacattt
    28081 ctcttccttt ctaactacaa ttatagtgta aaaattataa gaataaaaga gtatttgagc
    28141 acaatataat ctcacctttt aaaagaaatt attgggctga aactttttag tgattatttt
    28201 caactttcta ttgactttta aaaacaaagt gatatcattt agatatcaaa taatgggagg
    28261 tcattcttat gactgaaaaa ctaatcaatt caaaaccaaa tggtgtattc gcattgattc
    28321 tcattgagtt gacaatcgta cttggtatct ttatatttat aatgggggtt ggttcggaaa
    28381 acatttttgg aattattatc ggacctttac taatcgtaat tgcaggtcta gctcatgctg
    28441 gtttaaaagt tgtcaaacct caggaagctc tggttctgac actctttggt aattatacag
    28501 gtaccatcaa agaacctggt ttttactttg tcaatccctt cagcgtagca gtcaaccctg
    28561 caaaccacac tcgacttgga caaagtggtg atgttagcac aaaatctcct tttttaggag
    28621 ctaaatcatc aaatgacaat gatgtaaatc ttgaaattgg caagaaacac atttccctca
    28681 aagtcatgac cttgagcaat tctcgtcaaa aaatcaatga ttgcttagga aaccctgtag
    28741 aaatcggtat cgcggtaact tggagagttg tcgataccgc taaggcagtc ttcaacgttg
    28801 ataactacaa agaatatctt tcattgcaat gtgatagcgc cctccgtaat attgtccgca
    28861 tctatcctta cgatgtgtct cctaatgtgg atactacggg tgacgggcaa gcagatgaag
    28921 gtagtctccg tggctctagc gaaattgttg ctaaccgtat tcgtgaagaa atccaaagtc
    28981 gtgttgagga tgctggcttg gaaatccttg aagcacgtat cacttaccta gcttatgctc
    29041 cagaaattgc tgccgttatg cttcaacgcc aacaagcatc tgccattgtt gatgcacgga
    29101 agatgattgt agatggtgct gtaggaatgg ttgaaatggc actagaacgg ctcaatgaag
    29161 gggaattggt agaacttgac gaagaacgaa aagctgccat ggtttcaaat ctccttgtcg
    29221 ttctttgtgg caatcatgat gcacaaccaa ttgtcaacac aggaagtctt tactaaagat
    29281 ggctgaagct aaaaaaaagc agatccccct tcgactctca acaaagttat acgctgcact
    29341 cgcatcatgg gcagaagacg actttcgttc agtcaatggg caaatcgaat atctcctcac
    29401 agagtgtgtc aagcaacgga agaaagacgg aaaatacgta tcagaaacca ttgacgaacc
    29461 atttgagatt gatatttaac atcttctcct gtctgacaag tcggacagga gaattttttc
    29521 atcttttttt gtcaagtaac tttactttac aaaaaaaatg tgttatccta gtatggttga
    29581 tgaaaatcag tagattgaat cgaatataaa tacctaaagg agaaatcaaa atggcagtac
    29641 ctgcacgtcg cacttcaaaa gcgaagaaaa acaaacgtcg tacacactac aaagtaacag
    29701 ctccatctgt aaactttgac gaaactactg gagattactc acgttctcac cgtgtatcac
    29761 ttaaaggata ctacaaagga cgtaaaatcg ctaaagctgc atcagctgaa taatagaagg
    29821 gagataccat gcgcgtaaat attacacttg aacacaaaga atctggtgaa cgcttgtacc
    29881 ttacttctaa aaacaaacgt aacactccag accgccttca attgaagaaa tactcaccaa
    29941 aacttcgcaa acacgttgtg tttacagaag tgaagtaagc attcaatacg aatcaataca
    30001 gaagaaaaac gcttgatcag cgttttttct ttttgttaat ttcactatat tgcaagggaa
    30061 atcattcgaa tgactacctt tttcactacc ttttttgaaa taagaatacg gattcggacg
    30121 attaaaagta agagaaactc aaatgtaagt tggggttcct tttttgtata tttttcaaat
    30181 aacgcctcta cactatttgt agcaaattca ccaactacag ttgtatctta gttaaaataa
    30241 gttagaatat gtaagtgagt accagatata ccaagacatc gtcaccatct aaggtatatt
    30301 caaaatacaa aagttgacca actagatttc tgaatatcct tatatatcca ttcttaaaat
    30361 tggtttaaat agcgtagtct tttaaactag ttttgagaat ccaaaaaatc ttcctacata
    30421 tgtaagaaga ttttttagtt cagaatgatt agatttagct aatggatacc tatcctaccc
    30481 actcaccgtt agcattgact cgatagccat cgggtgtagt cgtgtttact aataaatctc
    30541 ctgaattata ggtatagtac catttaccag aaactgtaa
//
LOCUS       DAVMCN010000018        30330 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVMCN010000018 DAVMCN010000000
VERSION     DAVMCN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.018"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..787)
                     /locus_tag="VYP85_001006"
     CDS             complement(<1..787)
                     /locus_tag="VYP85_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1881539.1"
                     /translation="MLYVGIDVAKNKHDVTALNVRGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGNRL"
     gene            1043..1888
                     /locus_tag="VYP85_001007"
     CDS             1043..1888
                     /locus_tag="VYP85_001007"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1881540.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2035..3096)
                     /gene="dinB"
                     /locus_tag="VYP85_001008"
     CDS             complement(2035..3096)
                     /gene="dinB"
                     /locus_tag="VYP85_001008"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1881541.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            3491..5815
                     /gene="pflB"
                     /locus_tag="VYP85_001009"
     CDS             3491..5815
                     /gene="pflB"
                     /locus_tag="VYP85_001009"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1881542.1"
                     /translation="MVVKTVVESQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(6183..6401)
                     /locus_tag="VYP85_001010"
     CDS             complement(6183..6401)
                     /locus_tag="VYP85_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881543.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(6497..6735)
                     /locus_tag="VYP85_001011"
                     /pseudo
     CDS             complement(6497..6735)
                     /locus_tag="VYP85_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6728..7012)
                     /locus_tag="VYP85_001012"
     CDS             complement(6728..7012)
                     /locus_tag="VYP85_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881544.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(7624..7794)
                     /locus_tag="VYP85_001013"
     CDS             complement(7624..7794)
                     /locus_tag="VYP85_001013"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1881545.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(8444..9667)
                     /locus_tag="VYP85_001014"
     CDS             complement(8444..9667)
                     /locus_tag="VYP85_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1881546.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9835..11157
                     /locus_tag="VYP85_001015"
     CDS             9835..11157
                     /locus_tag="VYP85_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1881547.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            11159..13045
                     /locus_tag="VYP85_001016"
     CDS             11159..13045
                     /locus_tag="VYP85_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1881548.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            13213..13557
                     /locus_tag="VYP85_001017"
     CDS             13213..13557
                     /locus_tag="VYP85_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1881549.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            13567..14979
                     /gene="lacG"
                     /locus_tag="VYP85_001018"
     CDS             13567..14979
                     /gene="lacG"
                     /locus_tag="VYP85_001018"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1881550.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            15049..16728
                     /locus_tag="VYP85_001019"
     CDS             15049..16728
                     /locus_tag="VYP85_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1881551.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16854..18293)
                     /locus_tag="VYP85_001020"
     CDS             complement(16854..18293)
                     /locus_tag="VYP85_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1881552.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(18297..19646)
                     /gene="trkA"
                     /locus_tag="VYP85_001021"
     CDS             complement(18297..19646)
                     /gene="trkA"
                     /locus_tag="VYP85_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1881553.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19835..20683
                     /locus_tag="VYP85_001022"
     CDS             19835..20683
                     /locus_tag="VYP85_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1881554.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20698..21246
                     /locus_tag="VYP85_001023"
     CDS             20698..21246
                     /locus_tag="VYP85_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1881555.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            21253..21465
                     /locus_tag="VYP85_001024"
     CDS             21253..21465
                     /locus_tag="VYP85_001024"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881556.1"
                     /translation="MKIKEQTRKQVAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            21567..23249
                     /locus_tag="VYP85_001025"
     CDS             21567..23249
                     /locus_tag="VYP85_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881557.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            23234..24064
                     /locus_tag="VYP85_001026"
     CDS             23234..24064
                     /locus_tag="VYP85_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1881558.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            24257..24760
                     /locus_tag="VYP85_001027"
     CDS             24257..24760
                     /locus_tag="VYP85_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1881559.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      24814..25048
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25213..25776
                     /locus_tag="VYP85_001028"
     CDS             25213..25776
                     /locus_tag="VYP85_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1881560.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            25790..26416
                     /locus_tag="VYP85_001029"
     CDS             25790..26416
                     /locus_tag="VYP85_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1881561.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            26444..26833
                     /locus_tag="VYP85_001030"
     CDS             26444..26833
                     /locus_tag="VYP85_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1881562.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            26838..27287
                     /locus_tag="VYP85_001031"
     CDS             26838..27287
                     /locus_tag="VYP85_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV1881563.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            27415..28002
                     /locus_tag="VYP85_001032"
     CDS             27415..28002
                     /locus_tag="VYP85_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1881564.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVTPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            28392..29999
                     /locus_tag="VYP85_001033"
     CDS             28392..29999
                     /locus_tag="VYP85_001033"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1881565.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         9038 a         5277 c         6427 g         9588 t
ORIGIN      
        1 ctaaacgatt cccaatccca gtgaccgtcg tgatgaccga gttgaactca gccatcaagt
       61 cattgacaca tgtttccgcc ttgtcaatga gcctcttgta atgtttgatg atttcgaatt
      121 cacgagcagg agatgttgtt ccgatagaac gaggtgcaac tgagaggata tcctgaattt
      181 tagaagcggt caatcgctta atttctatca gcttatcaaa tcctgcctca agccttttct
      241 gaggattagg gtagcatgtc aagagttggt aggtatattc tgaatgcttt tcaacgattt
      301 tatccaactc aggaaagatg atatcaagac aacgagtgta ttgtactttc caatcagact
      361 gttttttctt gagacgatga atatgtctag ccagtatttt tagttctact tgccgattat
      421 cgtgttgaaa ttgttcacga ttggggtcag aaagaagttt aagagcgatg ccatgagcgt
      481 ctttcttatt cgttttagtc ttgcgaagtg ataatgattt ggcaaattcc ttgatgagca
      541 aaggagtgta ggtgtaaact ttatatcctt gttcatgcag gaagttcagt agattaaagg
      601 cataatgtcc ggtattttca agagcgatga gacagtcttg gttgagctgt cgaagagaca
      661 gatctaagag ttcaaaacca gctttattat ttgaaaaagt gagtggttta agaacagttt
      721 ttcctcgaac attcaaggct gtaacatcgt gtttattttt agcgacatca atgcccacat
      781 aaagcatggg agtacctcca gatatagtat ttcaagtcta cttggttatc cacgaacttt
      841 ttgccttgtt accatagacg agataaaacg tctatgcgtt atcaaactca ttaccaattg
      901 aaacaaaaag ctgttgttag accctttcgg aaatcgtcaa gcgattggag gaaatgaact
      961 aatccacagt ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgtta
     1021 aatataatat aaggagaaat atatgtatct tattgaaatt ttaaaatcta tcttcttcgg
     1081 gattgttgaa ggaattacgg aatggttgcc gatttccagt acaggtcact tgattttagc
     1141 agaggagttt atccaatacc aaaatcaaaa tgaagccttt atgtccatgt ttaatgtcgt
     1201 gattcagctt ggtgctattt tagcagttat ggtgatttat tttaacaagc tcaatccttt
     1261 taaaccgact aaggacaaac aggaagttcg taagacttgg agactatggt tgaaggtctt
     1321 gattgctact ttacctttac ttggtgtctt taaatttgat gattggtttg atacccactt
     1381 ccataacatg gtttcagttg ctctcatgtt gattatctac ggggttgcct tcatatattt
     1441 ggaaaagcgc aataaagcgc gtgctatcga gccaagtgta acagagttgg acaagcttcc
     1501 ttatacgacc gctttctata tcggactctt ccaagttctt gctcttttac cagggactag
     1561 ccgttcaggt gcaacgattg tcggtggttt gttaaatgga accagtcgtt cagttgtgac
     1621 agaatttacc ttctatcttg ggattcccgt tatgtttgga gctagtgcct taaagatttt
     1681 caaatttgtg aaagccggag aactcttgag ctttgggcaa ttgtttttac tcttggtcgc
     1741 gatgggagta gcttttgcgg tcagcatggt ggctattcgc ttcttgacca gctatgtgaa
     1801 aaaacacgac ttcacccttt ttggtaaata ccgtatcgtg cttggtagtg ttttgctact
     1861 ttacagtttt gtccgtttat ttgtataaga aaaaccttga aggggcaact cttcaaggtt
     1921 ttatactctt agaaaatctc ttcaaaccgc gtcagcttta tctgcaacct caaaacagtg
     1981 ttttgagcag cctgcggcta gcctcctagt ttgctctttg attttcattg agctttaaaa
     2041 tccagtcatg gtaatcccca ataggcggac acctctttct ttctcactta attcttcata
     2101 gagttgcagg gctatttggc ttatctgact agcatcttgt gttttttgag caatactttt
     2161 tcgtttggta agagttgaaa agtcctcgta gcggattttc aaaatgacaa tttttccagc
     2221 tttttcttgt tgatgtagat tgagagcgac tttttctgat agaagagtca gctctttttt
     2281 gatatcttcc tcagcacgga gaatcttccc gtaggttttc tccttgccga ttgatttacg
     2341 gatgcgattg gatttgactg gagagttgtg aatgccacga gcctttcgat acagatcata
     2401 gcctagtcta ccaaaacggt ctattagggt cacctcagga acttcaagta aatcagcacc
     2461 agtaaaaacg cccatttgat gaagacgttc tactgtcttt tttcctactc catgaaattt
     2521 ggaaatatcc atttgtttga gaaaatcctc agcctgttca ggtagaatca ctgtcaaacc
     2581 atgaggtttt tgataatcac tcgccatttt agctaagaac ttgttatagg aaataccggc
     2641 agaagcagtt agatggagtt cttgccagat atctttttga atgaggcgag caattttgac
     2701 cgctgacttg ataccgagtt tattttctgt cacatccaaa taggcttcgt caatactcat
     2761 gggttcaatc aaatctgtat agcgcttaaa aatagctcga atctggagtc ccacagcttt
     2821 gtatttctca taatttcctg agataaagac ggcctgggga caacgttcat aagcttcctt
     2881 ggaactcatg gcagaatgga caccaaaagc tcgagcctca tagctacagg tagaaacgac
     2941 tccccgccca cctgtttgtc gagggtcgct tccaataatg acaggttttc ctctgagttt
     3001 aggattatcc ttgatttcca ccgcagcaaa aaaggcatcc atgtcaatat ggatgatttt
     3061 tcttgacaaa tcatttaaca aaggaaaaat caacatgcct agcacctttt tatacttttc
     3121 aaaaatctct tcaaaccacg tcagcttcca tctgcaacct caaaacagta ttttgagctg
     3181 acttcgtcag ttctatttac aacctcaaag cagtgctttg agcagcctgc ggctagcttc
     3241 ctagtttgct tttcgatttc cattgagtgt tactgcttat tttcttttat tatacccttt
     3301 tttctgaaaa aaagaaaaaa ggactttatt tttttcaaaa atataataca gtttgaaata
     3361 aaatatagac tgttttagaa aagaaagtgt aaaaataggg attttgcact tgttgaaatc
     3421 ggttacttta tggtatactt gtcttatgaa tgtaacagat gactgttact agaaaaaaga
     3481 ggacattaat atggttgtta agacagttgt tgaatcacaa gatatttttg acaaagcttg
     3541 ggaaggcttc aaaggcgtag attggaaaga aaaagcaagt gtatcacgct ttgtacaagc
     3601 taactacaca ccttatgatg gagacgaaag cttccttgca ggaccaacag agcgttcact
     3661 tcacatcaag aaaattgtag aagaaactaa agcacactac gaagaaactc gtttcccaat
     3721 ggacactcgt ccaacatcta tcgctgatat ccctgctgga tttatcgaca aagaaaatga
     3781 agttatcttt ggtatccaaa atgatgaact cttcaaattg aacttcatgc caaaaggtgg
     3841 tatccgtatg gctgaaacta ctttaaaaga aaatggatac gaaccagacc cagctgttca
     3901 cgaaatcttc actaaatatg taacaacagt taacgacggt attttccgtg cctacacttc
     3961 aaatattcgt cgcgctcgtc atgcacacac tgtaactggt cttccagatg catactcacg
     4021 cggacgtatc atcggtgttt acgcacgtct tgctctttac ggtgcagact acttgatgca
     4081 agaaaaagta aacgactgga atgcaatcaa agaaatcgat gaagaaacaa tccgtcttcg
     4141 tgaagaagta aaccttcaat accaagcatt gcaacaagtt gttcgcctgg gtgaccttta
     4201 cggggttgat gttcgcaaac cagcgatgaa cgtgaaagaa gcaatccaat gggttaacat
     4261 tgctttcatg gctgtctgcc gtgtgattaa cggtgctgct acatctctag gtcgtgtacc
     4321 aatcgtattg gacatctttg cagaacgtga ccttgctcgt ggtacattta ctgaatcaga
     4381 aatccaagaa ttcgttgatg atttcgttat gaaacttcgt acagttaaat ttgctcgtac
     4441 aaaagcttat gaccaattgt actcaggtga cccaaccttt atcacaactt ctatggctgg
     4501 tatgggtaac gacggtcgtc accgtgttac taagatggac taccgtttct tgaacactct
     4561 tgacaacatc ggtaactcac cagaaccaaa cttgacagtt ctttggactg acaaattgcc
     4621 atacaacttc cgtcgctact gtatgcacat gagccacaaa cactcttcta tccaatacga
     4681 aggtgtaaca acaatggcta aagacggata tggtgaaatg agctgtatct catgctgtgt
     4741 gtctccactt gatccagaaa atgaagaaca acgccacaac atccagtact tcggtgctcg
     4801 tgtaaacgtt cttaaagccc ttcttactgg tttgaatggt ggttacgacg atgttcacaa
     4861 agactacaaa gtatttgata tcgaaccaat ccgtgacgaa gttcttgaat tcgaatcagt
     4921 taaagcgaac tttgaaaaat ctcttgactg gttgactgac acttacgtag atgccttgaa
     4981 catcatccac tacatgactg ataggtacaa ctacgaagct gttcaaatgg ccttcttgcc
     5041 aactaaacaa cgtgccaaca tgggattcgg tatttgtgga tttgctaaca ctgttgatac
     5101 attgtcagct atcaaatacg ctacagttaa accaatccgt gacgaagatg gctacatcta
     5161 cgattacgaa acaatcggtg actacccacg ctggggtgaa gatgacccac gttcaaacga
     5221 attggcagaa tggttgatcg aagcttacac aactcgtcta cgtagccaca aactatacaa
     5281 agacgcagaa gctacagtat cacttttgac aatcacatct aacgttgctt actctaaaca
     5341 aactggtaac tcaccagttc acaaaggtgt atacctcaac gaagatggtt ctgtgaactt
     5401 gtctaaactt gaattcttct caccaggtgc taacccatct aacaaagcta aaggtggttg
     5461 gttgcaaaac ttgaactcac tttctagcct tgactttagt tatgcagctg acggtatctc
     5521 attgactaca caagtatcac ctcgcgctct tggtaagact cgtgatgaac aagttgataa
     5581 cttggtaaca atccttgatg gttacttcga aaacggtgga caacacgtta acttgaacgt
     5641 tatggacttg aacgatgttt acgaaaaaat catgtcaggc gaagacgtta tcgtacgtat
     5701 ctctggatac tgtgtaaaca ctaaatacct cactccagaa caaaaaactg aattgacaca
     5761 acgtgtcttc cacgaagttc tttcaatgga tgacgccttg gatgcattga gctaatcaag
     5821 ttcttgaata ataaaaagga accctcggtc aaacgactga gggttttgtg cttgggatag
     5881 tctgagcaat tccttcggcg caatatgcaa tgtttttggg aaggaatagt ggaccgaatc
     5941 tgaaatataa tagattgaaa ctagaatagt acacctttat ttctaaaaca ttcttagaaa
     6001 tcgatttgac tgtcctgatc gatttgtcct attcttattt cattttacta tagtccactg
     6061 aaacgtctca aacagcgcta gaaattgact ggaattctct aagcgatttg ttcagatttt
     6121 atttcatttc atcataaaaa acaagacgac tggctaattg acaatcatct tgtttgatac
     6181 tgttaataaa attcgcgaag tttatcttga ttttctttaa aaaatttttc taaccaatcc
     6241 ataccataag cataactaaa accttctaat agaacagaga ggtcaatagt atcaaatccc
     6301 atgtctttta aatatttaaa ggtatcgaat ggtgaatgaa agtttttgta tttaataatt
     6361 gcaccaatat cttgcaaatc ctgctctctg atactcatca tcttcattcc taacacatac
     6421 tcaataggga ctactaaaac ggtcagattc tcaaatgagt acaaggattc gcataaactt
     6481 aagggaggtt gtttgttcat atttgctttg caacatgatt gttgagccat aactcttcgt
     6541 ggatgttaag attaaactgt tttcctacac gagcaataat ttcattgatt ttctgatttt
     6601 ggtcataaaa agcatcaaca tcttgtgtgg cacgtaaacc atgatattct aagacataac
     6661 cataattgtt aaagtcagat tttcctgaat taatttctta tttagggctt ggaagaccgg
     6721 tttcatttta tccatgtttg tatttctcca tcaatttttg aacattggtt aacttagcag
     6781 gtttatttaa tgaaatcaca tatttatgag ttggagtatg ctcttgaaag gcatacttca
     6841 agctaatttt ttgaaaacgg gttagttctt tggagtctag caacttttct acatcttggt
     6901 ttgttaaata agaatagtct tcaaaaataa cttttcgcaa atagcgaaac caatggcttg
     6961 cgttgaattg tgattgtttg gatgcctgta tcatataatc gtaccaatcc attgtcttcc
     7021 tcctataaaa tttagtttat attattgtag tttatattca aaaatgtagt ttttcttaat
     7081 tagctcgtat ctataggatg atactgaaaa tcttcttgtt gctttaaatc acaatcgaaa
     7141 aattctgttt ttcatcttag aaaagaatgt ttagaaatgt aaaatgaacc ttttttctta
     7201 tccgaaaacc ttactaaagt atataattta ggcagtcaat tctgtatgat aatgtttgta
     7261 ctatcgtcga gtttttgctt gattgcctaa cgagataaat tttagaagag ttttcggtgt
     7321 gatttgacaa gtttctgact ggaaggatag ttacactagt attgtttatt aaaatgagca
     7381 gatagagaaa atttggaatc tatttgctta ttatcaatcg tttttttagc ttatttgtct
     7441 tagattggta tagaactgag ctatggatta atcttcttct atcttatcct gttcctaaat
     7501 atgttggtag aaaaatgaag cagttgttac gagtgtctgt attgggaaaa attttgtcta
     7561 tagaattctt taaatgatat gaaggctagg aatgccaaaa cactgacata tttcgtttaa
     7621 agtctatcca gtctcttcaa ttgtatttgt agaaatgcta tcagtaatat attcgcgaac
     7681 actatgattt acaacagtgt ggtcgtacat ctttgtaact ttattataca acaaccattt
     7741 acaggtgtaa agttgagcag tgtctttagt aaatttaggg acttgttttg tcatagtttt
     7801 gatacctgta ttcgttgttt catgagcatt tgacgtttct tttcatgtag gcatttcaac
     7861 aattagaatg atatttttcc gaggatgaac ttatatattg tgacttttta gagttatgat
     7921 gcctcttgat ttgactatcg ctatcaattt catccacttt tacagtttca tggttttatg
     7981 aaccgaaaca tctaggtaca ggttttagca tcaattgatt gtttttgagc catatgaagt
     8041 tgaaacgtgg agatgctttt cttgtgataa cgccctattc aaagaggaat aaccgttttt
     8101 ggagagagtt cagtactatg tggcgctaaa tactatatgt aaaacatata ttaaacaaga
     8161 tttaactaag gagaattgta aaaacaaaaa tgagaatttc atataaagtt tattctagga
     8221 gtatgtatct tgaataaaaa tcgttattta agttcagggt tatgatgaat gtttttataa
     8281 taataaaatg cagctagaag aaaagttatt ttaatataaa tcactcaaca tagagagaag
     8341 gcggtttcct atatggaagt cgtcttgttt tcatattgtc taaatacgag atatctacta
     8401 caggttatag ttgatttaaa caggtctata gatttctaat atattaaggt gaaataatat
     8461 cttgtaatac attgctatgt tctatgaaaa aagcgacgat agctaatgca caagctccta
     8521 tacttccacg atgtttgttg taaggtaaaa tttcaatttc tatattacga gtaaagggaa
     8581 cgaagtggag ctggtcttgg attttatccc tgacttcatg agtgaaaggt tgataattaa
     8641 gcaattgact gttgatatag attttatcag caggattgat gaggaggaga tttgcaatag
     8701 aagtggctaa taaattgact cctttatcaa tttgttgacg taaagcggag tcgcctaaat
     8761 tataagccgt taaaagggtg tctaaatgaa tgtctttttc agtctttaca aggcttttta
     8821 gtacagttag ttgggaattt ttaaataata attgggcgtg tttgattaac caagcatccg
     8881 aaatatatgt ttgtaaacaa cctttttttc cgcattcaca atattgccca ttcaattcga
     8941 caatggtgtg tccaatttct ccgatataag gatttttaga ggctcctatt ttttcttttg
     9001 tgaaaaagga agtgtaaata cctaatccag cgtgtaggaa aataaagtta tcgggggtat
     9061 tgtgtggatt aaaaaggtat tgtcctatag ccatacaatc gatattattt tttacaataa
     9121 aaggaaaatt gaatctttta attacattta ataaattaaa agattcccat atggggttgt
     9181 ttgtaatgat acttccggag tctttgttat aatgtccagg tattgataag ccaaatccaa
     9241 gtaattttgt ttccaaaggg acgtactcta tagctgtttt tatcatattg gtaatggtgg
     9301 aattgatttc tgaaatagga taatcttcat tcaaaatttc tgtctcgaaa agagttttcc
     9361 cttgtaagtc acatagactg agaaagatac ctaggacgtt tatttcaata cctccaacaa
     9421 catacggaat attatctgtg atagaaatag tttttctacg tcttccagat ccggaaaact
     9481 cgctaaattc atcaccagtt tcgtatatga gggactgttc gcttagctct tttatgatgt
     9541 tagtcgttgt tgctggagta agtcctgttt cattaacaat atctgtacgg gatgttgctg
     9601 gatttcgata tagaaactcc agtatagtgg ctctattttg taaaaaggct gattgttttg
     9661 taatcatttg tttcctcctt tggtttattt tatattaaac ataagaaaaa atcaattaaa
     9721 attattattt tatacaaaga aaaaaatatt gtaaaaacaa caaaaaatat attgacaacg
     9781 ctttctgtta gtggtatatt taatttataa aaaataaaaa aaggagttcc ggtgatgaac
     9841 aatattttag cgtttttaga aacaaaagtc gctccgtttg gtgaaaaagt tggcaaccaa
     9901 cggcatttga aagctattcg tgaaggattt atgatggcaa tgcctttgat tttagtcgga
     9961 tctttatttc ttattctaat cagttggcct caagaggatt ttacaaattg gctgaatagt
    10021 gttggattgc taagtatctt gacaactatg aatcagtcaa cagtagcgat tatctccttg
    10081 gtcgcttgtt tcggtattgc ctacaggttg tcggaaggat atggtacaga tggtccgtcg
    10141 gcagggatca tagccttatc cagttttgta ttgatggcac ctcgtttttc gagtatggtt
    10201 tatgataaaa atggggagca ggtcaagcag ttatttggcg gcgcaatacc attttctagc
    10261 ctgaatgcat cttctttgtt tatggcgatt actattggat tggttacagc agagatttat
    10321 cgtatgttta tccagcgcgg aattacgata aaaatgccaa gtggtgtccc agatgtggta
    10381 agtaaatcat tttcagctct tttacctggc tttactactt ttgttttgtg ggctctggtc
    10441 ttaaaaggtc ttgaagcggc aggagttgca ggaggtctca acggactcct aggtgcaatt
    10501 gttggaacac cgcttaagtt aattgcagga acgcttccag gtatgattct atgtgttatt
    10561 gtaaactcat tcttttggtt ctgtggagtt aatgggggac aagttttaaa tgcttttgta
    10621 gatccagttt ggttacaatt tactacagaa aaccaagaag ctgtggctgc aggacaaaca
    10681 ctccaacaca ttattacatt accgtttaaa gatttatttg tatttattgg tggcggtgga
    10741 gcgactattg gtcttgcgat ttgtctcttc ctatttagta agagtcgtgc gaataaaaca
    10801 ttaggtaagc tagctattat accgtctatt tttaatatca atacagctat tctatttacg
    10861 tttccaacag ttttaaatcc gattatgctg attccgttta ttgctactcc tacaatcaat
    10921 gccttaatta cctatgtatc aatggctgta ggattagtac cctacacaac aggtgtaatc
    10981 cttccgtgga caatgccacc gatcatagga ggcttccttg cgacaggagc tagttggcga
    11041 ggagctctat tacaagttgt tttgattttg gtttctgtag caatttatta tccattcttc
    11101 aaaattgcag ataaacgcaa tcttgaaaaa gaaaaagcta ctgttggagg gaaataagat
    11161 ggttatcaga gtatttgatc agcagaaaaa tacttattct agctttgcct tagaggaatt
    11221 aagttactat ataaatcggg tctttaagac tgacatagaa cttgtcgagg agaaggaagc
    11281 ggatattttt gtaggattag tcaataaaga ggatagaaaa gaccatgttc ttatctcatt
    11341 agacaagggt aaggggagaa ttgagtctaa tacaattgta ggtttactta ttggaattta
    11401 ccgaatgttt catgaatttg gggttgtgta tactagacca gggcgcggac atgactttgt
    11461 tccagagtta cgatttgaag attttttaga taaagagcta tctatagatg aaacagccag
    11521 ttactatcat aggggagtat gtatagaggg agcagattca tttgaaaata tactagattt
    11581 cattgattgg ctacctaaga ttgggatgaa cagttttttc attcagtttg aaaatcccta
    11641 ttcttttttg aaacgttggt atgaacatga gtttaatcca tacctaaata aagaaaaatt
    11701 ctcaaatgaa ttagtacaag aattgagtga taggttggat aaagaattgc aaaaaagagg
    11761 tcttattcat catcgtgttg gtcatggatg gacaggtgag gttttaggtt actcttcaaa
    11821 atttggctgg gaatcaggtc ttagtatttc agaggagaag aaaccctatg tcgctgaaat
    11881 aaacgggaaa cgagaattat ttaatacggc tccgatttta accagtctgg atttttcaaa
    11941 tccagatgtg gcggataaga tggtagaaat tatcaaggat tatgccaaga aaagacctga
    12001 tgttaactac ttacatgtat ggttgtcgga tgctcgtaat aatatttgtg aatgcgaaaa
    12061 ctgtagacaa gaattggttt cggatcagta tattcgtatt ctcaatcaat tggatagggc
    12121 tttaacgagt gagggattag atacaaagat ttgttttctg ctttaccatg agttgttatg
    12181 ggcgcctcag aaagaaaaat tagataatcc tgaacgcttt accatgatgt ttgcaccgat
    12241 tacaagaaca tttgaaatga gttatgcaga tgtagatttt gacaattcca tacctacgcc
    12301 taaaccttat ctgcgtaata aaattatact tccgaattct cttgaggaaa atttatctta
    12361 tctttttgag tggcaaaaaa catttaaagg agatagtttc gtatatgact atcctttagg
    12421 gcgtgctcat tatggcgatt taggctatat gaaaattagt caaaccattt acagagatgt
    12481 atcttatctt tctaacctac atttgaacgg ttacatttcg tgtcaagaat tacgtgccgg
    12541 attccctcat aattttccta attatgttat gggggaaatg ctctggaaga agacaagaag
    12601 ttatgaagaa ttgattgaag aatacttttc tgctttgtat gggtcaaatt ggcagtctgt
    12661 tgttgaatat ttagaaaaat tatccagtta ttcctcatgt gattatttta atgcaattgg
    12721 cagtcgtcaa aatgatgttt tagcgaatca ttattatata gcttacaatc tagctgataa
    12781 ttttttgcca attattgagg aaaatatttc taagttatta aatagtcaaa aggatgaatg
    12841 gaaacagctc agttatcatc gtgaatatgt tgttaagatg gcgaaggctt tatatcttca
    12901 agcaaccgga aaaacaaggc aagctcaaga tgaatggaga aatgtgttga attatatccg
    12961 tgggcacgaa ttgctatttc aatctaattt ggatgtttat cgtgtaattg aagtagcaaa
    13021 aaattacgct ggtttccact tataaatcat aagtatagaa aatgaaccaa ggtattcaga
    13081 gaagattgat cctaaatatt atgaaattta aggattttta agatatttag ggtcgacttt
    13141 ctatttatat cgtagcgaag tcattttaat aatgatgtgt aaaagatgga tcaagattga
    13201 ggaggaagaa agatgaaatc aaaagaagaa ataaatatgc ttggttttac aattgtcgct
    13261 tacgcaggag atgcaaggtc agatttgatg gatgctttgg cgtttgcgag agatggatat
    13321 tttgaacagg caagagaatt ggttgagtct gcaaacgact caatagtgtc tgcccatcga
    13381 gaacagacta atttattagc ggaggaggca tctggagata attttgaagt gagttttatc
    13441 atgattcatg gtcaagatac cttgatgaca acgatgctat tgtatgatca ggtcaagttt
    13501 tttattgatg aatatgaacg aattcgaaag attgaagaac atattggttt gcaatgagga
    13561 ttagtcatgg aaaatttaca ggttaaagcc ttaccgaagg agtttttatt aggagctgct
    13621 accgctgctt atcaagtaga gggtgcaact agggtagatg gcaaaggaac aaatatgtgg
    13681 gatgtttatt tgcaagaaaa cagtccgttc ttaccagatc cagctagtga tttttattat
    13741 cgttacgaag aggatataac tttggcggca gaacatggtt tgcaggcttt gcgtttatct
    13801 atttcttggg ttcgtatatt tcctgatata gatggggagc ctaatatatt agctgttcgt
    13861 tattaccata gagtctttca gtcttgctta aaacataatg tgattccgtt tgtttcttta
    13921 catcattttg attcgcctca gaaaatgtta gaaacagggg attggttgaa tagagagaat
    13981 attgatcgtt tcatacgata tgctcgcttt tgtttccaag aatttacaga agtcaagcat
    14041 tggtttacaa tcaatgaact gatgtctctt gctgcaggtc aatatatagg aggtcagttt
    14101 cctccaaatc atcattttca attatctgaa gcaattcaag cgaatcataa tatgttgttg
    14161 gcgcatgctc ttgcagtcct cgaatttcat caattaggaa ttgagggaga gataggttgt
    14221 attcatgctt taaagccagg ctatcctatt gatgggcaaa aagaaaatat tttggcagct
    14281 aaacggtatg atgtttataa taataaattt ctattagatg gaactttttt gggctactac
    14341 agtgaggaca cgctttttca cttgaatcaa atattggaag ctaataattc tagctttatt
    14401 attgaagatg gtgatttaga aattatgaag agagctgcag ctcttaatac gatgtttggg
    14461 atgaattatt atcgttcaga atttattcgt gaatacaaag gtgaaaatag acaagaattt
    14521 aattcaacag gaataaaagg acagtcttct tttaaattaa atgctctagg tgaatttgta
    14581 aaaaaacctg gtattccgac aacagattgg gattggaata tttatcctca agggttattt
    14641 gatatgttgc ttcgtatcaa agaagaatat cctcaacatc cggtcattta tttaactgaa
    14701 aatggtacag cccttaaaga agttaagcca gagggcgaga atgatattat tgatgacagt
    14761 aagagaatcc gttatattga gcaacattta cacaaagttt tagaggctcg agatagagga
    14821 gtcaatattc aaggctattt tatatggtct ttgcaagatc aattttcttg ggcgaatggc
    14881 tacaataagc gatatggtct tttctttgtt gattatgaaa cacagaagag atatattaag
    14941 aaaagtgctc tttgggtaaa agggctaaaa cggaattaag gttagcgatt tgactgatgt
    15001 ttaatatatt ttaactatga gcttaaattt tttacaggag gagtttttat ggataagtta
    15061 gtcgctgcca ttgaaaagca acaagggaaa tttgaaaaaa tttctactaa taattatatg
    15121 atagctatta aagatggatt tattgctact atgcctttaa ttatgttttc aagctttttg
    15181 atgattatta ttatgattcc taaaaatttc ggagtagagt taccgagtcc agctattgcc
    15241 tggatgagga aagtgtatat gctaaccatg ggagttttgg gtattattgt ttcagggaca
    15301 gttgcaaagt cattggctgg aaatgttaat agaaaaatgc ctcctggaaa ggtaataaat
    15361 gatacttctg caatgttggc ggccatatgt ggctatcttg tattaactgt aacgcttgta
    15421 gttgatgaga aaacgggatc tacaagtttg tcgacaaact atttaggatc tcaaggattg
    15481 ataacttcgt ttgtcagtgc ctttattact gtaaatgttt accgattctg tattaagcga
    15541 gacattacta ttcatttacc taaggaagtt cctggggcta tatcacaagc ttttagagat
    15601 atttttcctt tttcttttgt tttacttatt agtggtttgt tagatattgt atctcggttt
    15661 agtttagatg ttccttttgc ccaagtattt caacaactat tgactcctat ttttaagggg
    15721 gcagaatcat atcctgctat gatgttgatt tggtttatgt gtgctttgct ttggtttgtt
    15781 ggaattcatg gaccatctat tgtcttacct gctgttacag ctttacaact gagcaatatg
    15841 gaagagaatg ctcaacttct tgcaaatggg cagttccctt atcattcttt aacacctaat
    15901 ttcgggaatt atatcgctgc tattggagga acgggggcta cctttgttgt accatttatt
    15961 ttgattttct ttatgcggtc taaacaatta aaatcggtag gtaaagctac aattactcct
    16021 gttttatttg cggtaaatga acctcttcta tttggtatgc ctgttatttt gaatccctat
    16081 ctttttgtcc cttttttgat gactccacca gtgaatgtat ttctaggaaa ggtatttatt
    16141 gatttctttg gaatgaatgg attttatatc cagttacctt gggcctttcc tggtcccttg
    16201 ggattgttaa ttggaacgaa ttttcaactt atctcctttg tatttttatc tttgatgtta
    16261 gttgtcgaca tattgattta tttgccattc tgtagagcgt atgatagaca gttactggtg
    16321 aaagaagata ttgcaagctc aaatgatatt attttagagg aggatacaag tgaaataatg
    16381 cctggtgaga tagatgtaat aaaaagtaag gagttgaaag tactggttct ttgtgcaggg
    16441 tctggaacaa gtgcgcaatt agccaatgca attaacgagg gcgctcaatt agcagaagtt
    16501 agagtgattg cgaattcagg agcgtacgga gctcattatg atattatggg tgtttatgat
    16561 ttaattattc tggccccaca agttcggagt tattatagag agatgaaggt ggatgcagaa
    16621 agattagata ttcagatagt tgctaccaga ggaatggaat atattcattt aacaaagagt
    16681 ccaagtaaag ccttacaatt tgtattggag cattaccaag ctgtgtagta agtttttcca
    16741 tcttttattt gagtaaagat tttgcttaca gataggcttg gatttaaaaa cgttccccct
    16801 tttttaatat aagaatccct ctttcacaat tgtaaaaaga gggattttgt attttatctc
    16861 ttagaccaag ttctcttcat aaagagaagg aggattgggt aaatctccaa gcgccctgca
    16921 atcattgcaa aggataggag aatttttgag atgggactaa agattgagaa actagaagtg
    16981 gttcctagaa taggcccgat attattgaaa cagctaaaga cagcgctggt cacgaccaga
    17041 aaatcattgc tatctaggct gacaataaag ataagcgcta gcaaaatcat agcatagatg
    17101 acaaagtact tgagaatctt atgctgggta tctttgtcaa tcaccgtttt attaacatgg
    17161 agggtcaaaa cacggtgggg cgataggatt gacaaaattt ggtttttggc aatttttgaa
    17221 aggatgaggc ctcgaataat cttgagtcca cctgcagttg atccagcaga gccaccgatt
    17281 gccatgagga aaaggaggat aaactgggag aagaggggcc agttggtaat atctccatat
    17341 ccaaaaccag ttgttgtaat gatgttggaa acctggaaga aggtcatttc aaagctcttt
    17401 gaaaaccctg ggtagaggta gagggtgttg aggctaatca agcctgtaga aaccagtaca
    17461 atgaccaagt aagccctaag ctcttcatct ccaaagaagg ccttgatgcg acggagcatg
    17521 aggtagtagt agaggttgaa atttactcca aaaaccagaa ctccgatact gaccagatag
    17581 gtaatcagtg agctgccata gtgggcaatt ccgtcgttat agacggtaaa gcctccagtt
    17641 cccgctgtcc ccatagcaat aacaaaacta tcgtagagag gcataccggc tagataatag
    17701 atgatgacaa agagggagaa gagagctaga taaaggagat agagaatctg ggcagtgttt
    17761 tttagtttgg atacaacctt gccaaaaaca ggacctggaa cctcagcctt catcacctct
    17821 aggtggctat ttttggcatt gtccataata gcaagtgcaa aaacaagcac tcccatccct
    17881 ccaatcaagt gggtaaaact tcgccagaag aggagggaac ggctgagaac cgaaacgtcg
    17941 ttcaaaatac ttgctccagt agttgtaaat ccagaactaa tttcaaaaaa ggcatcaata
    18001 aggctgggga tttgcccaga aaagacaaag gggagaccac caaagaaaga ccaaaggatc
    18061 caacagaggg caacgatcaa gactccctcc ttggcataaa tccgttgatt ttttggcttc
    18121 tgtaaactcc ctgaaccgcc taacaatacg agaatcccta tggtcgaaaa gagggctgta
    18181 aagacttggc tcgattcacg gtaatagaca gcaatcgcaa caggaaccaa aagaagaaca
    18241 gcttcaatca aaagtaattt tgaaaggagg taacgaatca tacttttatt catttcttac
    18301 ctcgcgatca agtcataaat cttggtgatg tttggcaaca aggttgttac taggagcttg
    18361 tctccaactt ccaacatatc ctccccagtt gggaaaatag tcttgccctt tcgaataatg
    18421 gctgcaataa gaaccccttt ttttaatttc agttgagaaa gaggtttggc agtcatttta
    18481 ttggcttcct tgatatggaa ttgcagggtt tcgatttggc cattggctag atggtgcatg
    18541 gcttgaaggt ctgaatactg ggcattaact cgaccacgaa taaagtgcat aatcgtatct
    18601 acagcgatgc ttttaggtgt gatgatactt gaaaaatcag gcgcattgat aatctcgagg
    18661 agactggtac gattgacctt agtaatattt ttctgtacac ctaccctgtc aaggaacata
    18721 gatgtaatca gattttcctc atcgacacct gttagagtcg caacggcatc atagtgttga
    18781 gcactttctt ccagcaggat atcttttgcg gttccatctc cttgaacgat gtagagattt
    18841 gggaatttct cgctaaagaa gctggcgatt tcaggattga tttcaatgac ttttgtatcg
    18901 atacgactat ctttgagaat accaagtaga taataggcaa ttctacctgc cccaacgatg
    18961 agaaggctct tcacggcgcg tgatttaaaa taattatgga agagtatcat atcgacacgg
    19021 ttaccagtga caaagattct atctttatcc tgtacagtca tgtcaccgct tggaatgata
    19081 atttgatgat ccctctctat cgcacagaca atgacattac caaatttttt acgaaaatca
    19141 gaaatgggca tttggcaaag accgctggtg gacttgacga caaattccat gaggctaacg
    19201 cgtccaccag caaagcgttc gacagacagg gcgttgggga agtcaatgat attcgcgata
    19261 gcgcgggcag ccaagagctc aggattaacg ataagagaaa aaccgagaat attcttttcc
    19321 ttgaaataag agttagaata ttcagggttc cgcacccgaa cgatagtttc tttagctccc
    19381 attttcttgg ctagaactgc tgcaatcatg ttgacttcat cgtgctcagt cagggcgata
    19441 aagatatcac aatcttggac gctggcttgc tcaagaatgg caaaatcggc cccgttacca
    19501 aggataccaa tgatatcaaa gcgactgaca atatgattga gaacagcttc gtcttgctca
    19561 atcagcaaaa catcatgctt ttctgcaacc aaggagcgac agagggcaaa accaactttt
    19621 ccccctccga caaggataat tttcataata aaacctactt tttcatgatg taactatcat
    19681 accctttttc aagaaaaaat gcacctacta gctaataacc agagttttta gtaggaaatt
    19741 tgctataagt taaaactata ccctaaccaa ttgaaatagc tattagcgac tttctctgaa
    19801 atatggtatg ataaaggata tacaaggaga taaaatgaat aataatttac tggtattaca
    19861 atcagacttt ggtctggttg atggtgcggt atcggctatg attggagtgg ctttagaaga
    19921 gtctccaacc ttaaaaatcc atcacttgac gcacgatatc acgccttata atatttttga
    19981 ggggagctat cgtctctttc agacggtgga ttactggcct gagggaacga cgtttgtatc
    20041 ggttgtcgat ccaggtgtcg gttcgaaacg taagagtgta gttgccaaga ctgcaaaaaa
    20101 tcaatacatt gtcacgccag ataatgggac gctttccttt atcaagaaac acgttggcat
    20161 tgtagccatt cgtgagattt ctgaggtggc caataggcgt caaaacacag agcattctta
    20221 taccttccac ggtcgtgatg tctatgccta tactggtgct aaactggcca gtggtcacat
    20281 tacttttgag gaagtagggc cagagctcag tgtggaacag attgtagagc ttccagtcgt
    20341 agcgaccatc atagaagatc atctggtgaa gggagccatt gatattctgg atgtgcgttt
    20401 cggttcgctt tggacctcta tcacacggga agaattttac aagttggaac cagaatttgg
    20461 tgatcgtttt gaagtgacca tctatcatgc tgatatgctg gtctatcaaa atcaggttgt
    20521 ctatggcaaa tcatttgcag atgtgagaat tgggcaaccc attctttaca tcaactctct
    20581 ctatcgttta ggtttggcta tcaaccaagg ttcctttgcc aaggcctata atgtaggtgt
    20641 cggttcatct tggaccattg aaataaagaa aatagaagga taaaatagga gaatagtatg
    20701 gaaatcaaat ttacaattaa acaagttgtt gctgtcggaa ttggcgctgc cctctttgtc
    20761 gtcatcggga tgatcaacat tccaacccct gttccaaata caagcatcca gcttcagtat
    20821 gcggtacaag cgctactttc tattattttt ggaccgatta tcggtttgct tgttgggttg
    20881 attggtcatg caatcaagga ctctcttgtt ggttatggtc tatggtggac ttggattatc
    20941 gctagcggac tctttggttt agttgtggga ctttttagaa agtacgttcg cgtgatcaat
    21001 ggtgtttttg actggaaaga tattcttatt tttaacctca ttcaactact tgcaaatgcc
    21061 cttgtttggg gtgtcttggc accacttgga gatgttgtga tttatcaaga agcggcagaa
    21121 aaagtatttg cacaaggaat tgttgcggga attgccaatg gtgtatctgt agctattgca
    21181 ggaactcttc tcttacttgc ctatgcagga actcaaactc gtgcaggaag tttgaaaaag
    21241 gactaatact caatgaaaat caaagagcaa actaggaagc aagtcgcagg ttgctcaaaa
    21301 cagtgttttg aggttgtaga tgaaactgac gaagtcagta accataccta cggcaaggcg
    21361 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgatggggaa ggctgggcaa
    21421 ctagtctttt tcgatgttta tagattagtt aggcaagtaa gctaggatag gaatcttttt
    21481 ggcgctaaga ttttaagaga agagactgca agaagggctt gatttatgat aaaatagaag
    21541 tctaagaagc gaatgaagag agtaagatga aagaagctat aattgagtgg aaggatttct
    21601 ctttccggta tgaaacacaa caagaaccga ccttgcaagg gatagacttg accatttaca
    21661 agggagagaa agtcttaatt gttggaccat ctggatcagg taaatctacc ttgggtcagt
    21721 gtttgaatgg gattattccc aatatttaca agggtcagac atatggagaa tttttgataa
    21781 agggtcaaac agcctttgat atgagcatct atgataagtc tcatctggtt agcacagttt
    21841 tgcaggatac agatgggcag tttattggct tgtctgtggc agaagatttg gcgtttgctc
    21901 tggaaaatga tgtgacagcc ctagatgaga tgaaaggtcg tgtttataaa tgggctgaaa
    21961 agctggacct tcttccttta ctggatcagc gccctcagga tttgtcaggt ggacaaaagc
    22021 agcgagtcag tctggctggt gtcttgattg atgaaagtcc gattctcttg tttgatgagc
    22081 cactcgccaa tctagatccc aagtcaggtc aggatattat cgaattgatt gaccagattc
    22141 ataaggaaga ggggacgacg actctgatta tcgagcaccg tttggaggac gttctgcatc
    22201 gccctgtgga tcggattgtc ttgataaacg atggtcgtat cctttttaat gggagccctg
    22261 accagttgct tgcgactgat ttattgactc aaaatggaat tcgagaaccc ctttatctaa
    22321 cgactctccg tcaattaggt gtggacttag tcaaggaaga acaattagca gatctggata
    22381 acttgtctat ctcaaaaggg caagtccagt tacagacgga actggtaaaa gaaaccccag
    22441 aattgcagtc actctttaga ctagaggaag tatctttttc ttatgatgat agaccgattt
    22501 taaaatccct acatttagat attaaaaagg gtgaaaagat tgctattgtc ggaaaaaatg
    22561 gagcagggaa atcaactcta gccaaggcta taagtagctt tattcagacg gaaggacgct
    22621 atctttggga aaaacaggat ataaaaggcg attctgttgc agagcgggcg gaacgagtag
    22681 gctatgtgct acaaaatcct aatcaaatga tttcaaccaa tatgattttt gatgaggtgg
    22741 ctctagggct ccgtttgcga ggtgtggatg agaaggaaat tgaaacgaga gtctatgaaa
    22801 ccttgaaaat ctgtggactt tatgaattcc gtaattggcc tatttctgcc ctgtcatttg
    22861 gtcagaaaaa acgtgtcacc attgcttcaa ttttggtctt aggagctgaa attattctcc
    22921 tagatgaacc gactgcaggt caagatcaga agaactatac tgagattatg gaatttctcg
    22981 aagagttaca tcaaaaaggg cataccattg tcatgattac ccatgatatg caattgatgc
    23041 tggattattc agaccgggtc cttgtcatgg tggatggaga attgattgcc gatactgttc
    23101 cagccagtct gttgagcgat cctgagctgt tagtaaaagc caatctaaaa gaaacctcca
    23161 tctttaactt ggctaagaaa ctagatgtgg atccactgga tttaacggca ttttacaaag
    23221 aaaggagaga gggatgcaag ctaaattaat cggttaccag catagagata ctgtgattca
    23281 tcgcttgtca ggagctggga aacttctctt tttcattctg gtatcattgg cggccatgat
    23341 tagctatgat accagaatgc tcttgctgat tgccatcttt tcagtctttc tcctctattt
    23401 atcagaaatt cgctttaaag atgtttcctt tgtagccgtt tttgcgacgg tatttgccgt
    23461 tttaaacgtt ttgatggtct atctcttttc tcccgagtat ggggttggac tttatggaga
    23521 gagaagtgtg atttggcagg gaatcggtgt ctacactcta accagccagg agctctttta
    23581 tctgctaaat ttggccatta agtatctttg caccattcct ctggctatta tctttttgat
    23641 gacaacccat cctagtcagt ttgcttccag tttaaatcaa attggtgtgc cctataagat
    23701 tgcttattct gtcagcctga ccttgcgcta tattccagat ttgcaggaag aattctttac
    23761 tatcaagatg tctcaggagg cgcgtgggat ggaattatcc aagaaagctt ctcttatgca
    23821 acgaatcaaa ggcaatctgc tcattattac gcccttgatt tttagctcgc tagaacgcat
    23881 tgataccatt gcgactgcca tggagcttcg ccgctttggg aaagagaaaa aacgcacatg
    23941 gtatagttat caggccttga aaaaaggaga ctatattacc ttgctcttgg caaccttgtt
    24001 tttagtagtt agtttactac ttatcttgca gaatcaggga cgattttaca acccttggaa
    24061 atagcttgaa aaaattgaaa aaatcaagtc gtttctattg acaatgattc tgaaagtgtt
    24121 atactaagaa agtagtttcg ctgatttact tcaaacctgt tgtgaggtaa gttaacgatg
    24181 ccttaaccac gctgtttgct gagcttgact ccgggcagtg tggctatttt tttgcaatgg
    24241 tgaaaggaag caagtcatga caaatcacat tgtattattt gaacctcaaa ttccacaaaa
    24301 tacgggcaat atcgcgcgta cttgcgctgc gaccaattct cccctccaca tcatcaagcc
    24361 tatgggcttt cctattgatg accgcaagat gaagcgggct ggattggatt actgggataa
    24421 gctagagatt tatttttacg agagtttgga agatttcata tctcagatga agggaaaact
    24481 ctatctgatt tcgaaattcg cggaaaaagt ctattctgag gtggatttat cgactgacga
    24541 ggaccattat tttctctttg gacgtgaaga caagggctta cctgaagatt ttatgcgaga
    24601 acatcctgag aaggctctcc gtattcccat gaatgatgaa catgtccgca gtctcaatgt
    24661 gtctaatacc gtctgcatga ttgtctatga ggctcttcgc cagcagaact ttgcaggtct
    24721 tgagctcgtc catacctatg aagtggataa attgaaataa aaaatgaaaa tgaacaaaat
    24781 gcttgcgctt gcaagcgttt tttgttatga taaaagagtc ttcagggcag ggtgtgattc
    24841 ccgaccggcg gtgactttaa ctaggaaatg atcttttcct tttatacttt gttgacaagc
    24901 tttgcctaac cagaagttat gcctacagct tgtcgcctag tctaaaagaa aaatctctat
    24961 ttccttctct ttaaagaagt ccgcgagcgc aagctgatgt ggtgagattc cacaaccgac
    25021 agtatagtct ggatgggaga agacgaaaga atagctttgt ctgttttgat agatttatag
    25081 ccggattgta accacttgct ttgtttttct ttaatagagt aagagggaac ttttgggata
    25141 taaaaagtga gaatagatag aggaatcctt tccaacttct tctgatttta tagaaaattg
    25201 gaggaacctg ttatgacaaa tacacgtcga ctttcgacca ttgcaatttt atcagccatc
    25261 tcatttgtgc tgatgtactt tgactttccg cttttaccag cggcatcttt cctcaagatc
    25321 gaatttagta tcttgccagt ccttgtgggt ctggtggtca tggatttgcc tgctgctcta
    25381 ggagtgctct tgcttcgctc actcttgaaa ttgcttctta acagccaagg agtgaatact
    25441 tacattggtt tgccgatgaa tatcgtagct ttgggagttt ttgtcatcgt atttgctttg
    25501 atttggaaaa aggaacggac aacccttcgt ttcctactag gctctctagc tggaactgtt
    25561 ggtttaacct tggccatgtt ggttctcaac tatgtttatg ctgttccttt gtacgctaag
    25621 tttgctaact ttgatattgg aaaaattttg ggactttcca actacctaat gaccatggta
    25681 ttacctttta acttgattga gggtgtaatc ttttccgttt cattctggtt gttgtacgtc
    25741 cttttgaaac caaccttaaa acactatgaa agataaacaa acatttttaa tgaagggcag
    25801 ttttgccctt ttacttttcg ttattcttgg ctatatggtc aaattttacc ctgaaatgtt
    25861 ggtcaatttt gaccaatcga ttcagactgc cattcgagga gacttaccag attatttgac
    25921 tattcttttt cgagccctca cacgtctgat tgatatccca gtgattatca cttgggttgt
    25981 cattacagct tttgtctttt atcgtaagcg atggaagata gaaagtttct tcatgctggg
    26041 aaatctggct ttggcaggtc ttttaatcgt gacctttaaa aatatctacc agcgcccacg
    26101 accagctatc ttacatctgg tggaagagaa gggattttcc ttcccaagtg ggcattctct
    26161 ggctgtaact ttgatggtag gtactctgat tgtcattctc agtcaacgaa ttaaaaatcc
    26221 agtctggaga aaaatcgtac aaatcgtcct tggcctctac ctagtcagtg tgctggtatc
    26281 aagagtctat ctgggagttc attacccatc agacgtcctt gccagtctct gtgtgggctt
    26341 gggagtcctg tttatcgagt ttcccttcta tgacaagctc cgcttccaat ggcgatttaa
    26401 aggcaaacag aagtgagtat cgaattccct tgaggagaaa gaaatgaaag tcaatatagc
    26461 agatcttcat ctgactcaac tatatttatc agaaaagaag ttgcaagata ttcagatgct
    26521 ttaccagtcg gcagaaacaa tccaagtcga tccaatcagt attcttgcct ttggagattg
    26581 tttgctgatt acagatgggc atcacagggc ttatcaggct ttattggcag gtcgggatac
    26641 gatttctgct gagtgggata gagatggtgg tgatgaacta tatcatctct atgcgcaagc
    26701 ttgcgaggaa agaaagattt actctgtttt tgatttagaa gatcgtatcc tagctcaaga
    26761 tgggtatgaa gcaaaatggt ataactggtg tgatggtttt aatcaagcag caactctttt
    26821 gttgaaaagg tagtgcattg tgttttgttc cttattataa ggtcaatcat tgtgaggaag
    26881 cttttgcttg gtatcaggat gtgaacttgg tttacctcgt agatggggtg aagcttcctt
    26941 acagtcaagc gaccttggaa gccatgtatt cctatttgga tcggcatggt gagctttttt
    27001 ggattgaagt caaggagaag ggagaatggt ttccaattgg ggatattaca ctatctcagg
    27061 ataatctccc cattgtgatt gggaattccg cttaccaaca tcgaggactt ggaaaaaaga
    27121 ttctaagtgc tttgattgaa ttggctcgag taaaaggatg gaaagaattg agagtcaaga
    27181 aaatctacac ctacaatcat gcttctagga ggtgtttcaa gtcgcttgga tttgtggaaa
    27241 atggagcaac agaaaaagga atgagtttta tattggaatt agtctaatcc tgccactttc
    27301 tcccccttaa cctttgacta ttccgcaaaa ttatcgtaaa ataaagagtg aatgataaaa
    27361 tgaggtcaga gtctgttcgc tctggcgata gtagtataaa tgaggagaaa cgctttgaaa
    27421 ttagaagtat ttgctgggca agaaaaaagt gaactatcta tgattgaggt agcgcgtgct
    27481 atcttggaac ttcgtggtcg cgatcatgag atgcatttta gcgatcttgt aaacgaaatt
    27541 caaaactacc ttggaacatc aaacagcgat atccgcgaag ctttgccttt gttctacaca
    27601 gagttgaact ttgacggtag cttcatctca cttggggaca acaaatgggg tcttcgttca
    27661 tggtatggtg tggacgaaat cgacgaagaa atcatcgctc ttgaagaaaa tgacgacgat
    27721 gaagtaacac caaaagctaa gaaaaaacgt gtcaatgcct ttatggatgg tgattcagat
    27781 gccattgact acaatgcaga tgatccagaa gacgaagatg catacgaagc agatccagct
    27841 ctttcatacg atgatgaaaa tccagatgat gaaaaaaatg aagtggaagc ttatgatgca
    27901 gaaatcaacg aaatcgctcc agatgacttg ggagaagatg tggatctcaa cgaagacgac
    27961 gacgagtttt cagacgacga cgctgaaacc agcgaggaat aagagttagc tattgacaat
    28021 tatcctattt ttaggtatca tattgtttgg gcacctcttt tagaggtcgg ggctccctag
    28081 ttcttaggga gctatttttg ttttttcaag aagttatctt cttgtatttt atactcaatg
    28141 aaaatcaaag agcaagctag gaaactagcc gtaggctgct caaaacactg ttttgaggtt
    28201 gtagataaga ctgacaaagt caggaacaca tatctacggc aaggcgacgt tgacgcggtt
    28261 tgaagagatt ttcgaagagt attagttgtg aatctggtgc agtcgtccca gattattctt
    28321 attagtaggg tcttgttttc tatatcccct cgtagttaac aagaccttga gcattttaga
    28381 aagaggaatc tatgtctacg aaatatattt ttgtaactgg tggtgtggta tcgtccattg
    28441 ggaaagggat tgtggcagcg agtctaggcc gtctcttgaa aaatcgtggt ctcaaagtaa
    28501 ccattcaaaa gtttgaccct tatatcaata ttgatccggg aaccatgagt ccttaccagc
    28561 acggggaagt ttttgtgaca gatgacggag ctgagacaga tttggacttg ggtcactatg
    28621 aacgtttcat cgatatcaat ctcaacaaat attccaacgt gacaactggg aaaatttaca
    28681 gtgaagttct tcgtaaagaa cgccgtggag aataccttgg ggcaactgtt caagtcattc
    28741 ctcatatcac agatgctttg aaagaaaaaa tcaagcgtgc cgctctaacg accgactctg
    28801 atgtcattat cacagaggtt ggtggaacag taggagatat cgagtccttg ccattcctag
    28861 aggctcttcg tcagatgaag gcagatgtgg gtgcggataa tgtcatgtat atccatacaa
    28921 ccttgcttcc ttacctcaag gctgctggtg aaatgaaaac caaaccaacc caacactctg
    28981 tcaaagaatt gcgtggcttg ggaatccaac caaatatgtt ggttattcgt acagaagagc
    29041 cagctggtca aggaattaaa aataaactgg cccagttctg tgatgtggca ccagaagccg
    29101 ttatcgaatc gttggatgtt gaacaccttt accaaattcc actgaacttg caggcacaag
    29161 ggatggacca aattgtttgt gatcatttga aattagacgc accagcagcg gatatgacag
    29221 aatggtcagc catggtggac aaggtcatga acctcaagaa acaagttaag atttcccttg
    29281 ttggtaagta tgtggagttg caagatgcct atatctcagt ggtcgaagcc ttgaaacact
    29341 ctggctatgt caatgatgta gaagtcaaaa tcaattgggt caatgccaat gatgtgacag
    29401 cagagaatgt agcagaactc ttgtctgatg cggacgggat catcgtacca ggtggttttg
    29461 gtcaacgtgg tacagaaggg aaaatccaag ccatccgcta tgcgcgtgaa aatgatgttc
    29521 caatgttggg agtctgcttg ggaatgcagt tgacatgtat cgagtttgct cgtcacgttt
    29581 taggtcttga aggtgccaat tctgcagagc ttgcaccaga aacaaaatac cctatcattg
    29641 atatcatgcg tgatcagatt gatattgagg atatgggtgg aacccttcgt ttgggacttt
    29701 atccgtctaa gttgaaacgt ggctctaagg ctgctgctgc ttatcacaat caagaagtgg
    29761 tgcaacgccg tcaccgtcac cgttatgagt ttaataatgc cttccgtgag cagtttgagg
    29821 cagcaggttt tgtcttttca ggagtttctc cagacaatcg tttggtagaa atcgtggaaa
    29881 ttcctgaaaa taaattcttt gtagcttgtc agtatcaccc tgaactgtca agccgtccaa
    29941 accgaccaga agaactctac actgcctttg ttactgcagc ggttgagaac agcaattagc
    30001 aaaatcagaa cctttgagaa aaatctcaga ggttttttgc atacgatgat attgcagtat
    30061 atctgaggta ggggtcctct gtatgtacct gctaccgttg aaatcaatag cgactccctc
    30121 ttgccctgtg ctagtgaatg gatttatcag tatattgaaa tgaaataaaa tttgaacaaa
    30181 ttaattcgga aagccaaatc aatttctagc aaagttttag gaactggatt gtatagtgaa
    30241 ttgaaataag atgtgaacat ctctatcaga aaagtcaaat taatttatag aaatatttta
    30301 gcagtcaaga tgtactgtta tagattcaat
//
LOCUS       DAVMCN010000019        27194 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVMCN010000019 DAVMCN010000000
VERSION     DAVMCN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.019"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            186..620
                     /locus_tag="VYP85_001034"
     CDS             186..620
                     /locus_tag="VYP85_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1881566.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            632..1822
                     /locus_tag="VYP85_001035"
     CDS             632..1822
                     /locus_tag="VYP85_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1881567.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1833..2324
                     /locus_tag="VYP85_001036"
     CDS             1833..2324
                     /locus_tag="VYP85_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1881568.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2339..3118
                     /locus_tag="VYP85_001037"
     CDS             2339..3118
                     /locus_tag="VYP85_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1881569.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3105..3923
                     /locus_tag="VYP85_001038"
     CDS             3105..3923
                     /locus_tag="VYP85_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1881570.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3923..4216
                     /locus_tag="VYP85_001039"
     CDS             3923..4216
                     /locus_tag="VYP85_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1881571.1"
                     /translation="MDTILFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVFLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4238..6139
                     /locus_tag="VYP85_001040"
     CDS             4238..6139
                     /locus_tag="VYP85_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1881572.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYIFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6199..7200
                     /locus_tag="VYP85_001041"
     CDS             6199..7200
                     /locus_tag="VYP85_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1881573.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANKRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7310..7645)
                     /locus_tag="VYP85_001042"
     CDS             complement(7310..7645)
                     /locus_tag="VYP85_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881574.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7656..7898)
                     /locus_tag="VYP85_001043"
     CDS             complement(7656..7898)
                     /locus_tag="VYP85_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881575.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7909..8451)
                     /locus_tag="VYP85_001044"
     CDS             complement(7909..8451)
                     /locus_tag="VYP85_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1881576.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(8467..8661)
                     /locus_tag="VYP85_001045"
     CDS             complement(8467..8661)
                     /locus_tag="VYP85_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881577.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8827..9777
                     /gene="rsmH"
                     /locus_tag="VYP85_001046"
     CDS             8827..9777
                     /gene="rsmH"
                     /locus_tag="VYP85_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1881578.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9789..10106
                     /gene="ftsL"
                     /locus_tag="VYP85_001047"
     CDS             9789..10106
                     /gene="ftsL"
                     /locus_tag="VYP85_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1881579.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            10110..12362
                     /gene="pbpX"
                     /locus_tag="VYP85_001048"
     CDS             10110..12362
                     /gene="pbpX"
                     /locus_tag="VYP85_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1881580.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            12364..13344
                     /locus_tag="VYP85_001049"
     CDS             12364..13344
                     /locus_tag="VYP85_001049"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1881581.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKIDFFFWGVGLLASLLTLAILYLM"
     gene            13953..16058
                     /locus_tag="VYP85_001050"
     CDS             13953..16058
                     /locus_tag="VYP85_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1881582.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDHTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLNSFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(16354..16836)
                     /locus_tag="VYP85_001051"
     CDS             complement(16354..16836)
                     /locus_tag="VYP85_001051"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1881583.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16931..18415)
                     /locus_tag="VYP85_001052"
     CDS             complement(16931..18415)
                     /locus_tag="VYP85_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1881584.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            18568..20175
                     /locus_tag="VYP85_001053"
     CDS             18568..20175
                     /locus_tag="VYP85_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1881585.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            20340..20507
                     /locus_tag="VYP85_001054"
     CDS             20340..20507
                     /locus_tag="VYP85_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV1881586.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(20500..21025)
                     /locus_tag="VYP85_001055"
                     /pseudo
     CDS             complement(20500..21025)
                     /locus_tag="VYP85_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21246..22691
                     /gene="cps4A"
                     /locus_tag="VYP85_001056"
     CDS             21246..22691
                     /gene="cps4A"
                     /locus_tag="VYP85_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV1881587.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            22693..23424
                     /gene="cps4B"
                     /locus_tag="VYP85_001057"
     CDS             22693..23424
                     /gene="cps4B"
                     /locus_tag="VYP85_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV1881588.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDRGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHIIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            23433..24125
                     /locus_tag="VYP85_001058"
     CDS             23433..24125
                     /locus_tag="VYP85_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1881589.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFDKIK"
     gene            24135..24824
                     /locus_tag="VYP85_001059"
     CDS             24135..24824
                     /locus_tag="VYP85_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1881590.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVMLGVFKARNKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            24839..26206
                     /locus_tag="VYP85_001060"
     CDS             24839..26206
                     /locus_tag="VYP85_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1881591.1"
                     /translation="MNGKIVKPSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISVYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRTYPNFKGSKKILLLTATFRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLERNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGVTGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            26193..26999
                     /locus_tag="VYP85_001061"
     CDS             26193..26999
                     /locus_tag="VYP85_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4422 domain-containing protein"
                     /protein_id="HEV1881592.1"
                     /translation="MERSRLIDVKIIVATHKEVKMPQDNSLYLPIHVGRDGKSDIGFI
                     GDNTGDNISSLNPYYCELTGLYWAWKNLDYNYLGLVHYRRYFTNKSQGYNENVNMDDL
                     ILSRANVEILLEKSDIIVPKKRKYYIETLYSHYAHTLNGEHLDLARKIIEQNSSEYLS
                     SFDKVMKQRSGYMFNMFIMKKELLDDYLPWLFSILDTMYEQMDLTDYTLFESRLFGRV
                     SELLFNVWLCQKGITPKEVPFMYMERVDLFEKGKSFLMAKFFGKKYGQSF"
BASE COUNT         8305 a         4775 c         6075 g         8039 t
ORIGIN      
        1 ttatttataa aaagatttat tttccttaaa aatggaatat tttgaaattt ctgtctatta
       61 aaatgattaa aaagataatg aaagcgctaa tattttttta aaaaaactat tgacaagata
      121 aaaataaagg attacaatgg ggaatataaa gtaaaccggt aaacctaaac aagaaaggag
      181 aaaagatgaa aattgtactt gtagggcatg gacattttgc tacagggatt tatagttctt
      241 tacaattgat tgcaggcaat caagaaaatg tggaggcgat tgactttgtg gaaggaatgt
      301 cagcagatga actcaagcaa aaaatcttac ttgcaatttc aaatgaagaa gaagttttaa
      361 tcctaagtga tctcttggga ggatcgccat tcaaggtttc ttctaccata atgggagaaa
      421 atccagccaa gacaatgaat gttctctcgg gtttgaactt agccatgtta atggaagcag
      481 tctttgctag aatggctcat agctttgatg aggttgttaa taaatcagta gtggcggccc
      541 agggcggagt tgtaaatggt aaagaattgt tttcaacgga tgcagaggaa gaggaagaag
      601 atttcgaatc gggtatttaa agggcaaaag aatgataaaa aaggttacga ttgaaaaaat
      661 aaaatcgcct gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc
      721 aatcgataag gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc
      781 gacgccagct acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg
      841 tttctggaca ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa
      901 catcgctcat aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattggc
      961 tcaccatgat ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg
     1021 agatggagag gctagagaag cagccttgaa agctgcagat aagttgattg aacgctatca
     1081 agaaaaaggt ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt
     1141 gattatcgac tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggtga
     1201 tcaaaaatac tacgatattg cagaaagcca tttctatgct tcagctaata atgtaatccg
     1261 tgatgacgct tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa
     1321 aggtgtaacg agacaagggt atagtgatga ttcatgctgg gcacgtggtc agtcatgggg
     1381 agtctatggt attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt
     1441 taagggtgtg accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga
     1501 tttgattttt aatgatggta gtgatcaatc acgagattct tcagcaacag ctatcgccgt
     1561 ctgtgggatt catgaaatgc taaaacatct cccagaggtg gatgctgaca aagatattta
     1621 taaacatgct atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt
     1681 tacccctggt gggacaagtc tcctccacgg tgtgtactca tggcattcag gtaaaggagt
     1741 ggatgaaggc aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa
     1801 agactggaac ctatattggt aggaggagaa atatgacaat gccaaatatt attatgaccc
     1861 gtatcgatga acggttgatt catggacaag gacaactttg ggtaaaatac ctaggttgta
     1921 atacggtcat tgttgccaat gatgaagtaa gcacggacaa gatgcaacaa actcttatga
     1981 aaacagttgt gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata
     2041 tcattcacaa ggctaatcct gctcaaacga tctttatcgt tgtaaaggat gtaaaggacg
     2101 ctttaacctt ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca
     2161 atgctactgg taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggcag
     2221 ccctcaagga attgagccaa actcatcaag taacatttaa tacgaaaaca actccaacag
     2281 gaaatgatgg agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat
     2341 gtcgattaat gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg
     2401 aatgctgtta ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat
     2461 tctaggtgat ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg
     2521 attcggtgtt ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg
     2581 taccttgatg gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc
     2641 tactccgatt gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg
     2701 tgcgcctgaa acggcgatga agcacttgaa aaaccataat ttgaagaaat tcaagttcac
     2761 tctaaatgca acaatttggt tgtttgcctt tattggattt accttgggtt gcttgggtgc
     2821 cctttcaatg gataccttgt tgaaactcgt agactacatt ccaccggtat tacttacagg
     2881 tttgacagtt gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat
     2941 ggctaagaaa gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa
     3001 catcccaaca attggtattg caattgtagg tactatcttt gctttgattg aattttataa
     3061 caagccaaaa acagcggatc atgtggtaga ggaggaagca cacgatgact ggatctaaca
     3121 aattaacaaa acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat
     3181 ttaactatag taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa
     3241 aacactatgg agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct
     3301 ataataccaa cccacacttc ctgcctttta ttaccagctt gcatcttgta atgttggaaa
     3361 atggccgtcc ggcaaaagaa acacgtagca tcaagatggc cttgatggga ccattggcag
     3421 gtattgggga ttctctttct caattctgtt tagctccatt gttctcaacc atcgcagctt
     3481 cgtttgctca agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga
     3541 ttttaacagc gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga
     3601 ttgataaact aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa
     3661 ccgtaattgc tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg
     3721 caggggaagt taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata
     3781 aggttgctcc agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag
     3841 aaaagaaatg gacaacatat aaactcgtta ttttaacagt tatcatcgga attatcggaa
     3901 gctggcttaa gattatagct taatggatac aatattgttt tatggaatag tgattgtctt
     3961 ggcagtgagt ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg
     4021 caaacagatg gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt
     4081 gttattgtct ggaattcatg gaaaaatcat ttctatccaa gatgacttgg tcttcttgca
     4141 gattgcaaaa ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga
     4201 actgcttttt aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt
     4261 ttttgaaaga atcgatggaa accaatgtcg tgattatatc ttgtcccact gttcaaaaga
     4321 ctatgagaaa gtcaagagtt cccttgaacg cttgatggac aatcgtttta tgtttgatag
     4381 tccttgggat atggagcctt gttcaaaaat ccatcaaatc cagccgatgg tatgggatca
     4441 agtatttgaa gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca
     4501 gtttatgata gggtatgtgg tagaaggaga taaggactat attcaaaagt gcaagttctt
     4561 tctatttgat tggattgagc aggtgagaga attttctcct caatccttga tgactagaac
     4621 cttggatacg ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt
     4681 tgacttgcta gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga
     4741 ctttatgaaa agccactatc gcgccaagta cacccttagt aactggggga ttttacaaac
     4801 aattccgatg cttgctatct attatttctt ttcagataag atggacctag aagaagctta
     4861 ccattttgct tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag
     4921 ccagtttgaa cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg
     4981 tctcttgctt ccagacttgc aagatagtta ccgagagttg ctggaaaaga tggcgaccta
     5041 tattcaaatg atgacaggct tagatggacg gactttggct tttggtgata gcgattctac
     5101 agaaacgaca gaaatgttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa
     5161 cggtctggat gttaaagtcg atttacttag cctcttgttc ctggggcgag aaaaggtcaa
     5221 gcgactgcag gaatttgaaa ggagagcttg gcagcctaag tccatgatct ttgaagactc
     5281 tggacatgtc tgcattaagg atgaacatcg ttatatattt ttcaaaaatg gtccgctagg
     5341 aagtgcccat agccatagtg acgagaatag tttttgctta cagtatcaag gccaacctat
     5401 tttcatagat gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag
     5461 tgcttggagt cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc
     5521 ctgggaatat gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt
     5581 gcattatatt gagggggctt attggtcagc agaacctgat ttgccttatc ttcacaagag
     5641 aaaaatcctc atgttggtag aggatgtctg gctcttggta gatgacatca ggtgtcaagg
     5701 tcagcatgag gcgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa
     5761 aatcaatcag ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc
     5821 tcctaaatac aatgagcttg aaagaagtag caaactcacc aagcgccaat tctttgagaa
     5881 tcagatgctg gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt
     5941 ctaccagaca gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga
     6001 aacagacaag ctgattctgt tattaagcga ggatattggt gtaggtgaaa aattgtgcct
     6061 cgttgacgga acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat
     6121 gattcgcttg cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt
     6181 agtaggaggt gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct
     6241 cagacctcga aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa
     6301 gagacacgtg aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt
     6361 gcgcgtagct taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc
     6421 aacagtttct caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac
     6481 caggtaatga taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc
     6541 atgcttctct tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat
     6601 tctcgtatca tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa
     6661 caccggacta gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc
     6721 tgtatcgaaa aaggttatga acattttctc ttgattacag cggatacgag tcgtttgagt
     6781 actcggattg agcgggcaag tggttttgtg gatgctttaa cagatgctaa taagcgtcac
     6841 gccagtctaa ccattgaaga taagcatacg aatttggaac aaattaagga atttttacaa
     6901 aaagaaatcg atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct
     6961 ctagtcttta ccgttatcaa agagttgaat tataacttgc cgcaagttgg gttgattggt
     7021 tttgacaata cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc
     7081 tcctttgagg aaggacaaca ggctacaaag attttgattg accagattga aggccgcaat
     7141 caagaagaaa ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa
     7201 aatgaaggaa aatgacttgc aatctctgtt aagaaataaa ataatcccac ctagaacaag
     7261 ctaggtggga ttatttgcct atgaaatgag aaattatggg agcaagctcc taaatcaact
     7321 gtttttgatc tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa
     7381 tgatggttac gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg
     7441 gaaaggatat gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta
     7501 ttttctcaag tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat
     7561 gagaaacagc tcctgaaata agggcaaaga aaaggaaaat actgataaaa acatgaatga
     7621 tcagtagtct agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt
     7681 gcaatacgaa gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagtata
     7741 gttttaaaaa tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt
     7801 agggtatcaa tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc
     7861 agaccaggat aacgtaactg tttcttttct tttttcatga gtttcctcct aatcctcatc
     7921 ttgatttttc ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa
     7981 gaaaatagaa ccgagaatac ttgatacacc atttcttata gtgagaagag aatgaaaata
     8041 gtcctgacct tcatctatga gtatcctgag aagaggagtt ataaaaaaca tccatagacc
     8101 aaagaacaaa cctgctttca gacctgggta gtgtagttgc ttgctttctt tctcattcag
     8161 catatctggt tcaatgactg tgatgcctgt ttttttcatt tggtaggtga catagccaga
     8221 agcgatgagg gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta
     8281 tttataggcc agaaggagtg gaataagatt tccgaaaatc atcagataaa agaggatgat
     8341 aaagacttgg ttcccaatac tatcggcctc acgccgtttg tattcgtcaa ggggaccaga
     8401 aataccgtat gtgcgtttga tcagtttttc agtgaaggtt tcttttttca tgagtttgct
     8461 ccttttttaa aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc
     8521 gagattgaga cagagttcca aggttggatt gtacttgtcg ttttcaatca tattgatagt
     8581 ctgtctcgag acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg
     8641 aaattctttc acacgattca tctgttctcc tttctgattt atgtcgtata tatttgacta
     8701 tattatagtc ttttaaacat aaagtgtcaa gtatttttga catatttttt gaagaaatag
     8761 tagtctcctt gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga
     8821 taagatatga caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg
     8881 cttgacgtaa agcctgacgg tatctacgtt gatgcgactt tgggcggagc aggacatagc
     8941 gagtacttat taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag
     9001 aatgccattg acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc
     9061 tttatcaagg ataacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa
     9121 attgatggaa tttgttatga cttgggagtg tctagtcctc aattggacca gcgtgagcgt
     9181 ggtttttctt ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg
     9241 acagcctatg aagtggttaa tcattatgac tatcatgatt tggttcgtat tttcttcaaa
     9301 tacggtgagg ataaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg
     9361 aagccgattg agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag
     9421 gaactcaaga agaagggtca tcctgctaag cagattttcc aggctattcg aattgaagtc
     9481 aatgatgaac tgggggcggc agatgagtcc atccagcagg ctatggatat gttggctctg
     9541 gatggtagaa tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg
     9601 ttcaaggaag cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc
     9661 aagcccaaga tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa
     9721 gccaataacc gctcgcactc agccaagttg cgcgtggtca gaaaaattca caagtaagag
     9781 ggaaaaagat ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac
     9841 ggttttcgcg tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag
     9901 ccattagtat tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa
     9961 tcaatgcgca gatagaggaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg
    10021 aactattacg tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca
    10081 atgaaaatat tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg
    10141 cgaccaaaaa tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt
    10201 tattatctgt ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag
    10261 gcactcgctt tggaacagat ttagcgaagg aagctaagaa ggttcatcaa accacccgta
    10321 cagttcctgc caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg
    10381 caacctccta taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga
    10441 ttctttacgt agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg
    10501 acatggaaga atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct
    10561 ttggagcaaa gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg
    10621 aagctgcaga ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg
    10681 gacaatttgc ttctagtttt atcggtctag ctcagctcca tgaaaatgaa gatggaagca
    10741 agagcttgct gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag
    10801 acggcattat tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag
    10861 tttcccaacg aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt
    10921 cctttatgga aacccagatg gatgcttttc aagagaaggt aaaaggaaag tacatgacag
    10981 cgactttggt cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg
    11041 atgcagatac aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa
    11101 gtaactatga gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata
    11161 atacctttcc aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga
    11221 ttcgagattg ggacgttaat gaaggattga ctggtggcag aacgatgact ttttctcaag
    11281 gttttgcaca ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta
    11341 cctggcttga ttatcttaat cgttttaaat ttggagttcc gacccgtttc ggtttgacgg
    11401 atgagtatgc tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg
    11461 gacaagggat ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg
    11521 acggtgtcat gctggagcct aaatttatta gtgccattta tgatccaaat gatcaaactg
    11581 ctcggaaatc tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa
    11641 ctcggactaa catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca
    11701 gcacaggcaa gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg
    11761 ctcagattgc tgacgagaaa aatggtggtt atctagtcgg ggtaaccgac tatattttct
    11821 cggctgtatc gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac
    11881 aacctgaaca ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg
    11941 cttcagctat gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa
    12001 gtcaacaaag tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag
    12061 aagaattgcg tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa
    12121 acagttctgc tgaagaaggg aagaatcttg ccccgaacca gcaagtcctt atcttatctg
    12181 ataaagtaga ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg
    12241 ctaagtggct caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag
    12301 atgttcgtgc taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact
    12361 aatatgttta tttccctcag tgctggaatt gtgacatttt tactaacttt agtaggaatt
    12421 ccggccttta tccaatttta tagaaaggcg caaattacag gccagcagat gcatgaagat
    12481 gtcaaacagc atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt
    12541 acttctgttt tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatgtg
    12601 ggaatgattt tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc
    12661 aaggtctttc gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt
    12721 ctaggtggag ttatcttcta tcttttctat gagcgcggtg gcgatatcct gtctgtcttt
    12781 ggttatccag ttcatttggg atttttctat attttcttcg ctcttttctg gctagtcggt
    12841 ttttcaaacg cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg
    12901 attagtttgt ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta
    12961 gtgattcttg ccatgattgg tggtttgctc ggtttcttca tctttaacca taagcctgcc
    13021 aaggtcttta tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct
    13081 atggctctcc accaagaatg gactctcttg attatcggaa ttgtgtatgt ttttgaaaca
    13141 acttctgtta tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt
    13201 atgacgcctg tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg
    13261 agcgagtgga agattgactt cttcttttgg ggagttgggc ttctagcaag tctcctgacc
    13321 ctcgcaattt tatatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt
    13381 taaatacaca atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata
    13441 tagtatattg aaactaaaat agtacacctc tacttctaaa acattgttag aaatcgattt
    13501 gactgtcctg atcaatttgt cctgttctta tttcatttta atatacagtt ttgagatggt
    13561 tgatagaact gacgaagtca gctcaaaaca cggttttgag gttgtagaca aggcgaagct
    13621 gatgtggttt gaagaggttt tcgaagagtg taaaaaaaca ttggtcagtt aaagtcaaaa
    13681 atcttgacct tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac
    13741 tagaacactt atttaaagta aaatagaaag aggtgagtct atgtttcatc tagaaatctt
    13801 cagaagtaaa gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt
    13861 agcggtttag ctagtctaaa ttttttaaaa caaaggtcaa agatagtcaa tatcagtaat
    13921 cataactaag taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata
    13981 acatggatga tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc
    14041 gccgttactt aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga
    14101 ctggtcaatt accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta
    14161 tgaaacaaga cggtgtcctt gcaaaactag gtcgaaactt gacagcagaa gcgcgtgagg
    14221 gcaagttgga tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct
    14281 cacgccgcac caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag
    14341 ttgtcgaagg tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca
    14401 aggaaattat ttctattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct
    14461 ttgaagaaaa tgtacaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct
    14521 tctttgatga aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta
    14581 aagggcttgc ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg
    14641 caacaactca agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt
    14701 tcaacgaagt gaaggtcaat gctccttcag cagagaatac ttttaaaatt cttcaaggca
    14761 ttcgtgacct ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag
    14821 cggtggatta ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc
    14881 ttgtcgatgt aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg
    14941 ttgaacgaga aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt
    15001 ttgaagcagc tctaaactat aaaacacgca ttgcagaatt ggaaaagaaa atcgaaaacc
    15061 acacagaaga tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa
    15121 tgacaggtat cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg
    15181 ctcatcgctt gcaagacaag gtgattggtc aagataaggc cgtagaagtt gtagctcgtg
    15241 ctatccgtcg taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct
    15301 ttgtagggtc tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt
    15361 ttggaaccca ggatgcgatt atccgtttgg atatgtctga atacagtgac cacacagctg
    15421 tttctaagct aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct
    15481 taacagaacg tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg
    15541 ctgaccctca agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg
    15601 gtcaaggaaa tacagtaaac ttcaagaaca ctgtcattat tgcgacctca aatgctggat
    15661 ttggctatga agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga
    15721 actccttctt ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcacact
    15781 tgactaagga agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct
    15841 tggctaagaa agacattgac ttggtagtca gtcaagcggc taaagattat atcacagaag
    15901 aaggttacga cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc
    15961 gtgataaggt gacagacttc cacttagatc atttagatgc taaacatctg gaagcagata
    16021 tggaagatgg cgttttggtt attcgtgaga aagcctaaga tagaattttg aggataaaaa
    16081 agaaggagcc agctgaaaaa aactggttcc ttttgaggta cgacgggcat gtcgtgtagt
    16141 agagatatac tattctagtt tcaatctact atagtagctc agaagtcggt acttaaacgt
    16201 gctatatcaa aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt
    16261 gaacggcatg cgttaaaagt tagttgaaca gccgtatgcc gaacggcacg tgcggtggtg
    16321 tgagaggggc tagagattat cccctactcg attttaaatc acatgacgtt caaaggcatc
    16381 atctgaaatc ccttgttcca agatgagttt tgcccattct ttagcagaga agaggctgtg
    16441 gtccttgtag tttccgcaag attcgatggt tgtccctggg acatcttccc aagtagtagt
    16501 ttcagcgatt tccttgagcg aatccttgat aacagctgcg attttagcac tggtgtgacg
    16561 tccccacata atcatgtgga agcctgtgcg gcaaccaaat ggtgaacagt caatcatgcc
    16621 gtcaatgcgg gtacggatga gtttggctaa gaggtgctcg atagtgtgaa ggccggcagt
    16681 agggatagag tcttcgtttg gttgcaccaa gcgaatatca taattggaga tgatgtctcc
    16741 ttttggtcct gtttcttccc caatcaagcg aacatagggt gctttgacaa tggtgtggtc
    16801 aagttcaaaa ctttcgacaa taacttcttt tgacatggta aatcctttca gttttcttct
    16861 ctcattatat cataaaggtt gctcctgaga cagagagaaa acctctccga ggctggagag
    16921 gttgaaatct ttacttacga tataagcggt cgtattggta gtatgggtca aaggttacgt
    16981 tgatacccag tttacgaagg acattcttgt cttcatcagt caagatgatg gttgagtggg
    17041 cttcgcttcc tttgaggttg ccgagttctt ccatagcgcg ggcagcatca ggattttctg
    17101 tagctgtgat agcaagtgca atcaggattt catttgaatg aaggcgtgga ttgcggctac
    17161 cgagatgatc gattttaaga ccttggattg gcttaacaac ttcaggttcg attagtttta
    17221 cttctttagc gatgtcagct gattttttga tggcgttgat caaggcagcg gctgtaggac
    17281 caaagagttc tgagttctta ccagtgacga tttccccatt tggcaattca aaggctaggg
    17341 ctggtccacc agtttcttct gctttttggc gcgcaacgac agcaacctta cggtctgcag
    17401 gtgtgatacc gaggtcgttc atgagcaact caattttctt gacggcagct tcgccaactt
    17461 tttcagcttt gaagtcaaga actgtttgat agtaacggcg gatgatttct tgtttagaag
    17521 cttcgacagc ggcctcgtca tctgtaatag cgaaaccaac catgttgaca cccatatctg
    17581 tcggtgaagc gtatggtgat tttccgagaa tacgttccaa catgcgcttg agcactggga
    17641 agatttcgat atcacggttg tagttgacag tggtttctcc ataggtttga agatggaagg
    17701 ggtcaatcat gttgacatca tcaaggtcag ctgtggcagc ttcataagcc aagttaactg
    17761 gatgatgaag gggaagattc caaacaggga aggtttcaaa tttagcgtag ccagatttga
    17821 tgccattgat ttggtcgtgg tacatattgg acatacacgt tgccaatttt ccagaaccgg
    17881 gtccaggagc ggttacgaca atcaagttgc gactggtttt gatgtagtcg tttttgccca
    17941 tgccttctgg ggaaatgatg tgatccatat ccgtcggata tcctttgatt ggataatgaa
    18001 gataagaatc aattccgttt ttctcaagtt gattgcggaa ggcatctgca gcgggttggc
    18061 cagcgtattg tgtaatgaca acggaaccaa caaaaatccc taattcattg aatttgtcaa
    18121 tcaaacgaag aacttcttgg tcataagaaa tgcctaagtc gccacgtgct ttggaatgtt
    18181 caatgttgct agcattaatg gcaatcacaa cctcaacctg ctctttcaat tcttgcaaga
    18241 gcttgatttt gttgtcaggt tcataaccag gaaggacacg agcagcgtgg aaatcttcta
    18301 acattttacc gccaaactct aagtagagct tgccgtcaaa ttggttaatg cgctccaaaa
    18361 tatggtcgcg ttgtaaattc aaatattgtt cagaactaaa agcttgtttt ttcatttttt
    18421 tacctctgga ctctattata ataaaaaatt ggaagttagg aaactacgga gctaaaaaag
    18481 aaattaaaaa gattaagcaa acgcttgcac aaaattttaa aaagtgctat catagactat
    18541 agattattaa aataatgagg taaacagatg caagaaaaat ggtggcataa tgccgtagtc
    18601 tatcaagtct atccaaagag ttttatggat agtaatggag atggagttgg tgatttgcca
    18661 ggtattacca gtaagttgga ctatctagct aagttaggaa tcacagcgat ttggctttct
    18721 cccgtttatg acagccctat ggatgataat ggctacgata ttgctgatta tcaagcgatt
    18781 gcggctattt ttggaaccat ggaggacatg gatcagctga ttgcagaagc taagaagcgt
    18841 gatatccgta tcatcatgga cttggtggtc aatcatacct cggatgagca tgcttggttt
    18901 gtcgaagcct gtgaaaatac tgacagccct gagcgagact actatatctg gcgcgatgaa
    18961 cccaatgacc tagattctat ctttagtggg tctgcttggg aatacgatga aaagtcaggt
    19021 caatactatc tccacttttt cagcaagaaa cagccggatc tcaactggga aaatgaaaaa
    19081 cttcgccaga aaatttatga gatgatgaac ttctggattg ataaaggtat tggtggtttc
    19141 cgtatggatg ttattgacat gattggcaaa attcctgacg agaaggtagt caataatggt
    19201 cctatgctcc atccctatct caaggaaatg aatcaggcga cctttggaga taaggagctc
    19261 ttgacagtag gggagacttg gggagcaacg ccagagattg ccaagctcta ctctgatcca
    19321 aaggggcaag aattgtctat ggtcttccag tttgaacata tcggtcttca gtatcaagaa
    19381 ggtcagccta aatggcacta tcaaaaagag ctgaatatcg ctaagttaaa agaaatcttc
    19441 aacaaatggc agacagagtt aggagttgag gacggctgga attccctctt ctggaacaac
    19501 catgacctcc ctcgtattgt ctcaatctgg ggaaatgacc aagaataccg cgaaaaatct
    19561 gccaaagcct ttgcaatctt acttcatctc atgagaggaa ctccttatat ctaccaaggt
    19621 gaggagattg ggatgaccaa ctatccgttt gaaacactgg atcaagtaga agatattgaa
    19681 tccctcaact atgcgcgtga ggctcttgaa aaaggtgttc cgattgaaga aatcatggac
    19741 agtatccgtg ttattggacg tgacaatgcc cgtaccccta tgcaatggga cgagagcaaa
    19801 aacgctggtt tctcaacagg tcaaccttgg ttggcggtta atccaaatta cgagatgatc
    19861 aacgtccaag aagcgctggc aaatccagat tctattttct atacctatca gaaactggtc
    19921 caaattcgca aggagaatag ttggctaatt cgagctgact ttgaattgct tgatacggct
    19981 gataaggtct ttgcttatat acgtaaggat ggcgaccgtc gcttcctagt tgtggctaac
    20041 ttgtccaatg aagagcaaga cttgacagta gaaggaaaag tcaaatctgt cttgattgaa
    20101 aacaccctag ctcaagaagt ctttgaaaaa caaatcttag ttccatggga tgctttctgt
    20161 gtggaattac tataaatatt ttttgcagaa aaatttaaaa ttgaaatcgt ataaaaacaa
    20221 gggaggactg tataaaaggc agaaatcctt tgttttttat aaccaaggtt tataaacctt
    20281 cattctcgaa attcaattaa ctttacaaat tcccactatt aaggagaaag aagacgaaca
    20341 taaagaagcg tatccttagt gcaggcctga cttttacatc tgctttgctt ttagctgctt
    20401 gcgaccaatc aggttcagat acaaaaactt actcatcaac ctttagtgga aatccaacta
    20461 catttaacta tctattagac tattacgctg ataatatagt caattgaaac aagaacaaga
    20521 caaaagagcc tcataaaagg tattgcaact tggtaatacc tttttgaggt gctttttgat
    20581 atgagcccat gttttctcaa taggattgta ctcaggtgag tagggaggaa gaggtaaaag
    20641 tttatgccca aactcttcgc ataaaagttc tagcttcccc attctatgga atcttgcatt
    20701 atccataata ataaccgatg gtgtggttaa tgttggtaag agaaatttct gaaaccaagc
    20761 ttcaaaaaag tcgctcgtca tcgtctcttc gtaagtcatt ggagcgatta actcaccatt
    20821 catttgttag acctgcaatc aaagaaatcc tctgatatct tcttccagat actttgcctc
    20881 ttcttaactg accttttaat gagcgaccat attctcgatg aaaataagta tcgaatcctg
    20941 tttcatcaat ctaaacaggt gctaggtgct ttaaactatt aaaattctta agaaataagg
    21001 ctactttttc tgggtcttgt tcataattag attgaaacta gagtagtaca cctctgcttc
    21061 taaaaaattt ttagaaatcg atttaactgt cctgatcgat ttgtcatgtt cttatttcat
    21121 tttactatat ttttgtttcg cgggaagtct actaagatac ttaaagatgc agatagtaaa
    21181 aaaatgtaga cattaccgta aaaaagtgat ataatcgtat gatgttcaat gtataggtgt
    21241 taatcatgag tagacgtttt aaaaaatcac gttcacagaa agtgaagcga agtgttaata
    21301 tagttttgct gactatttat ttattgttag tttgtttttt attgttctta atctttaagt
    21361 acaatatcct tgcttttaga tatcttaatc tagtggtaac tgcgttagtc ctactagttg
    21421 ccttggtagg gctactcttg attatctata aaaaagctga aaaatttact atttttctgt
    21481 tgctgttctc tatccttgtc agctctgtgt cgctctttgc agtacagcag tttgttggac
    21541 tgaccaatcg tttaaatgcg acttctaatt actcagaata ttcaatcagt gtcgctgttt
    21601 tagcagatag tgagatcgaa aatgttacgc aactgacgag tgtgacagca ccgactggga
    21661 ctgataatga aaatattcaa aaactactag ctgatatcaa gtcaagtcag aataccgatt
    21721 tgacggtcaa ccagagttcg tcttacttgg cagcttacaa gagtttgatt gcaggggaga
    21781 ctaaggccat tgtcctaaat agtgtctttg aaaatatcat cgagtcagag tatccagact
    21841 acgcatcgaa gataaaaaag atttatacca agggattcac taaaaaagta gaagctccta
    21901 agacgtctaa gaatcagtct ttcaatatct atgttagtgg aattgacacc tatggcccta
    21961 ttagttcagt gtcgcgatca gatgtcaata tcctgatgac tgtcaatcga gataccaaga
    22021 aaatcctctt gaccacaacg ccacgtgatg cctatgtacc aatcgcagat ggtggaaata
    22081 atcaaaaaga taaattaacc catgcgggca tttatggagt tgattcgtcc attcacacct
    22141 tagaaaatct ctatggagtg gatatcaatt actatgtgcg attgaacttc acttcgtttt
    22201 tgaaattgat tgatttgttg ggtggaattg atgtttataa tgatcaagaa tttactgccc
    22261 atacgaatgg aaagtattac cctgcaggca atgttcatct tgattcagaa caggctctcg
    22321 gttttgttcg tgagcgctac tcactagcag atggcgatcg tgaccgcggg cgcaatcaac
    22381 aaaaggtgat tgtggctatc cttcaaaaat taacgtcaac cgaagcactg aaaaattata
    22441 gcacgatcat taatagcttg caagattcta tccaaacaaa tatgccactt gagactatga
    22501 taaatttggt caatgctcag ttagaaagtg gagggaatta taaagtaaat tctcaagatt
    22561 taaaaggtac aggtcggacg gatcttcctt cttatgcaat gccagacagt aacctctatg
    22621 tgatggaaat agatgatagt agtttagctg tagttaaagc agctatacag gatgtgatgg
    22681 agggtagatg aaatgataga catccattcg catatcgttt ttgatgtaga tgacggtccc
    22741 aagtcaagag aggaaagcaa ggctctcttg acagaatcct acaggcaggg ggtgagaacc
    22801 attgtctcta cctctcaccg tcgcaagggc atgtttgaaa ctccggaaga gaagatagca
    22861 gaaaactttc ttcaggttcg ggaaatagct aaggaagtgg cgagtgactt ggtcattgct
    22921 tatggggctg aaatttacta cacaccagat gttctggata agctggaaaa aaagcggatt
    22981 ccgaccctca atgatagtcg ttatgccttg atagagttca gtatgaacac tccttatcgc
    23041 gatattcata gcgccttgag caagatcttg atgttgggaa ttactccagt cattgcccac
    23101 attgagcgct atgatgctct tgaaaataat gaaaaacgcg ttcgagaact gattgatagg
    23161 ggctgttaca cgcaagtaaa tagttcacat gtcctcaaac ccaaactttt tggcgaacgt
    23221 tataaattca tgaaaaaaag agctcagtat tttttagagc aggatttggt tcatatcatt
    23281 gcaagtgata tgcacaatct agacggtaga cctcctcata tggcagaagc atatgacctt
    23341 gttacccaaa aatacggaga agcgaaggct caggaacttt ttatagacaa tcctcgaaaa
    23401 attgtaatgg atcaactaat ttaggagaaa tgatgaaaga acaaaacacg atagaaatcg
    23461 atgtatttca attatttaaa accttgtgga aacgcaagct aatgatttta atagtggcac
    23521 ttgtgacagg tgcgggggct tttgcatata gcacttttat tgttaagcca gaatatacga
    23581 gtaccacgcg aatttacgta gtgaatcgca atcaaggaga caagccgggg ctgacaaatc
    23641 aggatttgca ggcaggatct tatctggtaa aagactaccg tgagattatc ctttcgcagg
    23701 atgcattgga aaaagtagcg acaaatttga agttggatat gccagcaaaa acgttagcca
    23761 gcaaagttca agtgactgta ccagctgaca ctcgtatcgt ctcaatctct gtcaaggata
    23821 aacagccaga ggaagccagt cgtatcgcta attctctacg agaagttgct gcagaaaaga
    23881 tcgtcgctgt aacgcgagta tctgatgtaa cgacacttga agaagcgcga ccagctacga
    23941 ctccctcttc tccaaatgtt cgacgcaatt ccttgtttgg ttttcttgga ggagcagtcg
    24001 taacagtaat tgctgttctt ttgattgagt tgctggacac ccgtgtgaaa cgtcctgaag
    24061 atgttgaaga tgtactgaaa attccacttt tagggctcgt tccagatttt gacaaaataa
    24121 aataggagga agttatgcca acattagaaa tctcacaggc aaaattggat tctgtaaaaa
    24181 aggcagagga atattataac gctttgtgca cgaacctaca gttaagtgga gatggtttga
    24241 aagtattttc tatcacttct gtgaaaatag gagaaggaaa atcaacgact tccgccaata
    24301 tcgcttgggc ttttgcgcgt gcaggttaca aaacgctgct gattgatgga gatattcgca
    24361 attctgttat gttaggtgtc tttaaagcaa ggaataagat tacaggcctg acagaatttt
    24421 tatcaggaac tacagactta tcacaagggc tttgtgatac caatatcgaa aatctctttg
    24481 taattcaggc tggctctgtg tcaccgaatc cgacagctct tcttcaaagt aagaatttca
    24541 ctacaatgct tgaaaccttg cgtaaatatt ttgactacat cattgtagat actgctcctg
    24601 ttggtgtcgt gattgatgcg gctattatta cgcgaaactg cgatgcttct attttagtga
    24661 cggaggcagg tgaaataaat cgtcgggata ttcaaaaagc aaaagaacag ttggaacaca
    24721 caggaaagcc gtttttggga attgtgttga ataaattcga tacttcagta gacaaatacg
    24781 gttcttatgg aaattatgga gattacggga aaaataaaaa ataggtcggg ggatagagat
    24841 gaatggaaaa atagtaaagc cttcattggc cataatccag agttttcttg ttattttatt
    24901 gacttatcta cttagtgctg tgagagaagc ggagattgtt tcaacaacag ctattgcact
    24961 ttatatcctc cattattttg tcttttatat cagtgtttat gggcaggatt tctttaaaag
    25021 gggatatttg attgaacttg tccagacatt gaaatatatc ctattctttg cactagcgat
    25081 tagtatttct aattttttct tagaggatcg atttagtatt tccagacgag gcatgattta
    25141 cttcctcaca ttacatgctc tcttagtcta tgtgctaaac ctatttatca agtggtattg
    25201 gaagcggact tatcccaact ttaaaggaag taagaagatc ctcttgctta cagcaacttt
    25261 tcgtgtcgaa aaggtactgg atagattaat agaatcaaat gaggttgttg gggagttggt
    25321 agccgtcagt gtcttagata aaccagattt tcagcatgat tgtttaaagg tagtagcaga
    25381 gggggagata gtaaactttg cgactcatga ggtggtcgat gaagtcttta tcaatcttcc
    25441 gagtgaaaaa tacaatattg gagagcttgt ctctcagttt gaaacgatgg gaattgatgt
    25501 aacagttaat ctaaatgctt ttgatcgtag tttggaacgt aacaagcaaa ttcgtgagat
    25561 ggcaggatta aacgttgtga ctttttctac aacattttat aagactagtc atgtaattgc
    25621 taagcggatt attgatatca tgggtgcatt ggtcgggttg atattatgtg gtttagtcag
    25681 tattgtactg gttcctttga ttcgaaagga tgggggctct gctatttttg ctcagacgcg
    25741 tataggaaaa aatggtcgtc agttcacctt ttataagttt cgctctatgt gtgtagatgc
    25801 cgaggcgaaa aaaagagaac tcatggaaca aaataccatg cagggtggaa tgtttaaggt
    25861 ggacgatgat cctcgtatca cgaaaattgg tcgttttata cggaagacta gcttggacga
    25921 gctaccacag ttttataatg ttctaaaggg agatatgagt ttggttggca cacggccacc
    25981 aacagtggat gagtatgaac actatacccc agaacaaaaa cgtcggctaa gttttaaacc
    26041 tggtgtaaca ggcttatggc aggtcagtgg acgaagtgaa atcaaaaatt tcgatgaagt
    26101 tgtcaaatta gatgtggctt atatagatga ttggacaatc tggaaagata ttgaaatttt
    26161 attgaagaca gttaaggtag tattgatgaa ggatggagcg aagtagattg atagatgtaa
    26221 aaatcattgt ggcaacgcat aaagaggtta aaatgcctca agacaatagt ctttaccttc
    26281 caatacatgt tgggagagac ggtaaatcag atattggttt tatcggtgat aatactggcg
    26341 ataatatatc ctctctaaat ccatattatt gtgagttaac gggactttat tgggcatgga
    26401 agaatcttga ttataattac ttaggtttag ttcattaccg tcgttatttt acaaataaat
    26461 ctcaagggta taatgaaaat gtcaatatgg atgacctcat tttgtctcga gctaatgttg
    26521 aaatattatt agagaaatct gacataatag ttccaaagaa gcgaaagtat tatattgaaa
    26581 ctctttattc acattatgcc cataccctta acggagaaca tctggatctt gctaggaaaa
    26641 ttattgagca aaatagttca gagtatcttt catcctttga taaagtgatg aaacaaagaa
    26701 gcggttatat gttcaatatg tttatcatga aaaaagaact attagatgat tatttaccgt
    26761 ggcttttttc tattctggat actatgtacg aacagatgga cttgactgac tatactttat
    26821 ttgagtcacg tttattcggg cgagttagtg agttgttgtt taatgtttgg ttatgtcaaa
    26881 aaggaataac gcctaaagag gtaccattta tgtacatgga gagagtggat ttgtttgaaa
    26941 aaggaaaatc ttttttaatg gctaaatttt ttggaaagaa gtatggacag agtttctagg
    27001 atatgaaagt aactattatt ggacaaataa aaaataagag aacaggtctt ggaaaggcga
    27061 ttaatgattt tagggattat tgttgcaatc gtgctacaag agtaacggaa atagatataa
    27121 caaataattt taatttttta agctctcttt ttcaaatttt aatatctgat acagatgttt
    27181 attattttac tcca
//
LOCUS       DAVMCN010000020        26158 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVMCN010000020 DAVMCN010000000
VERSION     DAVMCN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.020"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            103..966
                     /locus_tag="VYP85_001062"
     CDS             103..966
                     /locus_tag="VYP85_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881593.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRRIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            complement(1255..2646)
                     /gene="argH"
                     /locus_tag="VYP85_001063"
     CDS             complement(1255..2646)
                     /gene="argH"
                     /locus_tag="VYP85_001063"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1881594.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDLIGSLAH
                     VQMLGQTGILSLEESEKIQAGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGHVLDKLVHLKGVLLDLAENHVETIMPGYTHL
                     QHAQPISFAHHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKKPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGNLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(2675..3871)
                     /locus_tag="VYP85_001064"
     CDS             complement(2675..3871)
                     /locus_tag="VYP85_001064"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV1881595.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQTGATTIAHGCTGKGNDQVRFEVSIAALDPNLKVIAPVREWKWSREEEIHYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITSSPEAAPDMPEYIDI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSPATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(3888..4694)
                     /locus_tag="VYP85_001065"
     CDS             complement(3888..4694)
                     /locus_tag="VYP85_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1881596.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQNGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKKSGELDKLIEDAFKASIEK"
     gene            complement(4901..5542)
                     /locus_tag="VYP85_001066"
     CDS             complement(4901..5542)
                     /locus_tag="VYP85_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881597.1"
                     /translation="MIELENITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(5539..7647)
                     /locus_tag="VYP85_001067"
     CDS             complement(5539..7647)
                     /locus_tag="VYP85_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1881598.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRHFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHALLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(7699..7986)
                     /locus_tag="VYP85_001068"
     CDS             complement(7699..7986)
                     /locus_tag="VYP85_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1881599.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            8412..8732
                     /locus_tag="VYP85_001069"
     CDS             8412..8732
                     /locus_tag="VYP85_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1881600.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(8784..9371)
                     /locus_tag="VYP85_001070"
     CDS             complement(8784..9371)
                     /locus_tag="VYP85_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1881601.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            9613..10284
                     /gene="sdaAB"
                     /locus_tag="VYP85_001071"
     CDS             9613..10284
                     /gene="sdaAB"
                     /locus_tag="VYP85_001071"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1881602.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMNTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            10293..11165
                     /gene="sdaAA"
                     /locus_tag="VYP85_001072"
     CDS             10293..11165
                     /gene="sdaAA"
                     /locus_tag="VYP85_001072"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1881603.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            11187..11819
                     /locus_tag="VYP85_001073"
     CDS             11187..11819
                     /locus_tag="VYP85_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1881604.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(12077..13927)
                     /locus_tag="VYP85_001074"
     CDS             complement(12077..13927)
                     /locus_tag="VYP85_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1881605.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(13966..15126)
                     /locus_tag="VYP85_001075"
     CDS             complement(13966..15126)
                     /locus_tag="VYP85_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1881606.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            15184..16350
                     /locus_tag="VYP85_001076"
     CDS             15184..16350
                     /locus_tag="VYP85_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1881607.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            16489..16815
                     /locus_tag="VYP85_001077"
     CDS             16489..16815
                     /locus_tag="VYP85_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1881608.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            16802..17395
                     /locus_tag="VYP85_001078"
     CDS             16802..17395
                     /locus_tag="VYP85_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1881609.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            17388..18299
                     /locus_tag="VYP85_001079"
     CDS             17388..18299
                     /locus_tag="VYP85_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1881610.1"
                     /translation="MRKWTKGFLIFGVATTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSANHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            18362..19426
                     /locus_tag="VYP85_001080"
     CDS             18362..19426
                     /locus_tag="VYP85_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881611.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEERAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISTLVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(19497..20357)
                     /locus_tag="VYP85_001081"
     CDS             complement(19497..20357)
                     /locus_tag="VYP85_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1881612.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLESLPSAFYHQLDANQLEVQPILG
                     QDFKTLAQEK"
     gene            complement(20632..21618)
                     /locus_tag="VYP85_001082"
     CDS             complement(20632..21618)
                     /locus_tag="VYP85_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1881613.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(21890..23365)
                     /locus_tag="VYP85_001083"
     CDS             complement(21890..23365)
                     /locus_tag="VYP85_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1881614.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEVLNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(23449..24372)
                     /locus_tag="VYP85_001084"
     CDS             complement(23449..24372)
                     /locus_tag="VYP85_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1881615.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(24386..25315)
                     /locus_tag="VYP85_001085"
     CDS             complement(24386..25315)
                     /locus_tag="VYP85_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1881616.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYSLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(25634..25855)
                     /locus_tag="VYP85_001086"
     CDS             complement(25634..25855)
                     /locus_tag="VYP85_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881617.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(25809..26069)
                     /locus_tag="VYP85_001087"
     CDS             complement(25809..26069)
                     /locus_tag="VYP85_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881618.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         7833 a         5705 c         4721 g         7899 t
ORIGIN      
        1 aatttatttt tactttcttt tttacttttt acactgctat gatacaatat ttttaacaag
       61 attttattat ttgttaactt ttttcacaga aaggagaaaa tcatgcgtta tgatttcgga
      121 aaggtctata aagaaatacg tgagtcaaag gggctgaccc aagaagaggt ctgtgggggt
      181 gttctctcaa gaaccagctt atcaaaaatc gaaagtggca agacaacccc aaaatatgaa
      241 aatatggaat ttcttctccg tcaaatcaat atgagttttg aagagtttga atatatctgt
      301 caactttatc aaccaagtca acgcacagag attatgcaaa cctatctcaa tatgcgttcc
      361 attatcggga ccagcgatct tgtcaattta tttcaaaaat gccaagacta cctcaagacc
      421 caccacgatc tccctataga agaaatcaga gatatgcttg aagttgtcat ttatatccgt
      481 caacacgggg caggggaact atcagatcac gcagaacagg ttgtcaaaaa actttggaga
      541 agaattgaaa aacaagatac atggtatgag agtgatctaa aaatcctcaa taccattctt
      601 ttcagttttc ccattgaata cctccatctc atcactggaa aaatattgca acgcctagaa
      661 gtctataaaa actatcaaca tttatatgac ttgcgaatag caatcctgct caacctttcc
      721 acactctatc tatacaatca agataaaaac atgtgtaagc aaatctgcta cactttacta
      781 gaggacgcca agaataagaa aagctacgat aggctggcta tctgctatgt ccgtattggg
      841 atttgtacag acgattctaa acttatccaa aaaggtttct cactcctaga gctgaccgag
      901 gaaacttcta tgctgtctca tctcaaaaaa gaagtagaga cccattatca accaaagaaa
      961 ttataaaaaa gtcgagggat ttcctcgact ctttacatat tatttgttcg ttagttctta
     1021 ataccagcca ttgttaaacc agaagttttt agctctgcca agccacatag tgtgcttact
     1081 actatgtgtc catgtcacca tgaatcgccg aacgatttaa cgagaaagta tgacttttac
     1141 gtttatccca actcaattat gacatttttt tcaaaagtca atatatctca ctttttcaac
     1201 gacaagaaag aggctgccaa tcgaccaacc tcttattctg aacccatcac tccatcactt
     1261 tttagcttca ttcgctttct tagcgactgc aatctggtat tcgacttggt caaatcctgt
     1321 gcctcccaag gaatttcgtc tttgaacagc agttttaggt tgcaagtaga catagatatc
     1381 ctcggtaatg agagaatgat aggtttgtaa ttcctccaaa gtccaatctt gaagattttt
     1441 agcagacttg atagagtcta gcactaatct tcccacaacc tcatgagctt ctctaaatgg
     1501 caagcctttc cctgccaaat aatctgccaa ctcagtcgca tttgaaaagt ccttctctgt
     1561 agactcttgc attttttcct tgtttacctg caagctggat aacatacctg ccaatacatc
     1621 gagagaattt aaaatcgttt cgaccgtgtc aaacattcct tccttatcct cttgcaaatc
     1681 cttattataa gctaagggca aggacttcat gactgtcaac agtccaaaca gattcccata
     1741 aactctacca gtctttcctc gaatcaactc agccatatct ggatttttct tttggggcat
     1801 aatagaggaa cctgttgtaa acgtatctga caaggtaatg aattggtact caaaactaca
     1861 ccaattgatc atttcttcgc aaaaacggct catgtgcatc atgagtatgc tggcatttga
     1921 cagaaattct aagataaaat cgcggtcact aacagcatcc aaagaatttg tataaggttt
     1981 cttaaactcc agcaaatcgc tagacaattg gcgatcaatg gggaaagtcg ttcctgccaa
     2041 agctgccgca cctagagggc ataggtctgt atgcttctgg ttaaattcaa aacgttcact
     2101 gtctctctga aacatattgt agtaagccat caggtgatgg gcaaaactaa taggctgggc
     2161 atgttgcaga tgggtatagc ccggcataat agtctccaca tgattttccg ccaagtctaa
     2221 taaaacacct ttgagatgaa ccagtttatc taagacatgg cctagttgtt ccttgagata
     2281 caagtgcata tctgtcgcaa cttggtcatt tcgagaacga gctgtatgta acttccctgc
     2341 aaggggacca attttttctg tcaacaacac ttccatattc atatgaatat cttcgtttgc
     2401 gatatcaaag tcaagttggc ctgcctctag ctcttctaaa agctctttca agcctgcttg
     2461 gatcttttct gactcctcca aactcaaaat gcctgtctga cccaacatct gaacgtgagc
     2521 taaagaacca atcaaatcaa atttagctaa tttctggtca aaagatatac tcgcaccaaa
     2581 gcgctctacc cagtcttcga cagtaccttc aaagcgacca ccccataatt ttgtattctt
     2641 agccatatca catccacctc tctatccaat cgtcctattt ggcgcttttt tgaacctcag
     2701 aatgaacctt ggttggaagt ccccacaact taataaagcc aacagctgca tcttggtcaa
     2761 aggtatctgc actagtatac gtcgccaaat tttcatcata aagtgaattt ggtgatttcc
     2821 gagccacgac ctgagcgctt cccttataga gtttgacttt tgcagtccca ttgacaactt
     2881 tttgagtctc tttaatataa gcaatcaagg cttgcgtagc cggactaaac cacaaagcat
     2941 tataaatgag atttgataat tcattttcta tgattggttt aaaatgagcc acttctctca
     3001 caagcgtcaa atcctcaatt tccttatgag ctgtcagcaa ggtcactgcc cctgggcatt
     3061 catagatttc tcttgattta atcccaacta agcgattttc cacgtggtca atccgtccaa
     3121 ccccatgttt cccagctatt tcattgagtt tttgaatcaa atctgccaat tttaacactt
     3181 ctccattgag ggaaacaggg acaccttcac taaactcaat atcaatgtat tctggcatat
     3241 ctggagccgc ctctggagaa gatgtgatgc caaaggcttc ttctggagcc tgattccatg
     3301 gattttccaa aataccacat tcattggcac gtccccaaag attttggtcg acagagtaag
     3361 gattgtcaag gtcagcagga acaggcaccc cattttcctt ggcataatga atttcttcct
     3421 ccctagacca tttccattca cgaactggcg caatcacttt taaattggga tccaaggctg
     3481 caatcgatac ttcaaaacgt acttggtcat tccccttacc tgtacaacca tgggcaattg
     3541 tagtcgctcc tgtctgatgc gctatttcaa ccaatttttt agaaataaga gggcggctca
     3601 aggcagatac caaggggtac ttttgttcat aataggcatg tgactgaaga gccactagca
     3661 cataatctgt agcaaattcg tccttaacat caataacata agattcgact gccccaacct
     3721 tgagagcctt atcatggatg aagtctaagt ctttcccttc acccacatcc atacaaactg
     3781 caacaacatc atagtctttc tttaaccagg taatagcaac tgatgtgtct aaaccgccag
     3841 aataggccaa aattactttt tctttactca tgttcttttc cttctttcta tttttcaatg
     3901 gacgctttaa aggcatcctc aatgagtttg tctaattctc cagacttctt caacttttga
     3961 atggttttat cgactgcctc tttcaattcc ttgctatctt ttttcatggc taccgcgtag
     4021 gaatcatctt gctctttttc aaaattgagg tctgcgattg ctaaatcagg attattttcc
     4081 acaaatccct tggcaacagg ttcttcaaag ataacggcat ccacttgtcc tgattttaaa
     4141 tctgtgatta aattcccatt tttaggcaga gatacgaggg aagaattttg tagcaagtct
     4201 ttcgccatcg tctcttgaat cgaaccattc tgtgctccga cctttttctg cgctaagtcg
     4261 ttgacagact gataagtggc caagtcagat tttttgacaa tgagtttatt ttttgcagta
     4321 tagtagggag ttgaaaaatc gaacaccttg ctccgttcat ctgtcttaga aacaccagat
     4381 atggcaagat cggcttttcc tgattgaaca ctagccagta cattgtcaaa actcatggga
     4441 gatagttcca attcgacacc tagttctgtt gcgatagctt tggctaattc gatatctgaa
     4501 cccacaatct gatttttccc atctaccact ttttgatatt caaatggagc aaaatctgga
     4561 ttgagagcta caaccaattt tcctttggac ttgatggctt caattccagc cgattgattg
     4621 ttgctacaag caaatagtag ggggagcatc actaaaccaa acatcgtcat caacaccttc
     4681 ttcatcttat tcataacaaa gcctccttta tgtttattct ttttggttgt ataaataata
     4741 ctcctatact catcctttgt caagtctaaa ttgaaaaaat tttcaatttg aaacaaaaaa
     4801 acctagaaat actacataaa aatgtcattt ctaggcgtat ttatgctatt tctctctgga
     4861 aaatatgagt attcagtcag tcaaaaggag ctgaacgaac tcatttcccc tcgcccaatt
     4921 caatgatccg atgacattgt tgggctacat aagcatcgtg ggtcacaata atgactgttt
     4981 tcccctctcg attcatctct aagagaaact tcaagaccaa atctctattt tcagggtcca
     5041 gagaacctgt tggttcatcg gctaaaatca gctggctggg ttttaagatg gctctagcaa
     5101 ctgcaattcg ttgttgctcc ccaccagata actcggaaac cttttggtgc aaagtagctg
     5161 acaaacctac cctctctaaa atctcttcca cctttttgag cttgtctttc ttagacaatt
     5221 tcacatattt cagcgccagc ataagattgt actcgaccgt ttcatcatca atcagggcaa
     5281 aattttgaaa cagataagag atatgttcac ggattattgt ttgcgactta gcagaattaa
     5341 ctgctagatt tgtctgacca aaaatctcat accgtccgct ataatcacca tctatcaaac
     5401 ctaataaatt taacaaggtc gacttaccac taccactctt gccaacaatg gctaccaaat
     5461 ccccctgatc aatcctgaga gataagttat ccaaaatcac ttttcctcca atggttttgg
     5521 taatattttc caactcaatc ataagatgcc ccctttcaat aactctacta gacttctttt
     5581 ctccatccta gaagccaagc ctagcacaaa tagtatatcc aaacatgtaa aacctgcaaa
     5641 aagtaggagt ggcaagagcg catgggcaaa gaaaatcaag actagaagag gcagactata
     5701 gcccagcaag agcagaacga ggagagggcg gtagcgatcg accagtttcc accccataaa
     5761 cttcttggta ataatatccc tgcgcttcaa taagaaagtt attactagta agaagtagga
     5821 aatcatcatg ctaaggagac caaacaaagc aaagagtagg ttaaaattcc gaacagcatc
     5881 tcgataagaa tccactttct cttgttgaat ggcttgaata gatgaaaatt ttaaataatt
     5941 tccatctgac aatttctcaa ctaactctgt aatctctttt tgatgttgaa ccgtattttc
     6001 aattttaatc ggattattta agccagttgt tgacagggag gctttctcat cccacatcat
     6061 atcagaatca ttgaccaagc taataattgg attggagaga ttttcctttc gcttatcact
     6121 atatgggaaa aatgaccaat ctccttcata ataggcaatc tcgacatcca tctcctctat
     6181 cgttcgtttt tgctgctctt catacttcat cgaatgaaag gcaattaact tccccaagag
     6241 ctgattttta tcttcttcac ctttcgtact tgctggcatc aaaataactt ttttaatacc
     6301 ggtatctggt agcttgaatc ccttgctctt tagaaaatgg cgattggcat agtaaacatc
     6361 caccgtatct gttaactgat attgctgaat ctgttctgat tggacaaaat tttttacagg
     6421 aagactgcta ctctgcacat agcccgcctg cgttttttct accaaatcct gataaaatcg
     6481 atagaaataa tccaatgcct tccctgagcc tgccaactgc tcttgccaca agttatcatt
     6541 gagttggaaa gtttctaagg tcagataatt tccttggctg atccactgtt tctggtaatc
     6601 caactctttg ttttcttgct ccaaactttt tcctacccca actagcaaga ctgtcagtaa
     6661 aatggtagtt ccaattttca tcaaataatt aaagagtaga ccaaatttga aagatgaaaa
     6721 acctttcagc agagagctga ttgtcatttt ttggattaag aggtaagtca accaactgat
     6781 aaagagataa agctgcaaca gcaaaaaatg agacaaccac agcataggaa acaaatcttt
     6841 tggcttataa tcaagcaaga aaaacacgcc tagattgatc acaagagccc cacctaggag
     6901 gaggtaaagg ttgcctttta caacatcagc taaaacagcc ctatcttgaa aaccaagtaa
     6961 tttttgtacc ccaactcttt tcatctccat catcggttga tacactgtca ctaacacaag
     7021 aagcaaaata gccaagacaa aaacaatggc agataaaagc aaatctcgat ttatgacttc
     7081 cactgcactt ttgtaggtcg gctctagcaa ggtagcctgg tctatcttga aaaaatcgct
     7141 ccatttctgt acaatcctat ccttgtccat ctcttgtgta gaagttatcg tatagcgacc
     7201 atttaaacta cgagatgtat ccttgatata ggtttgaaaa gtcataagct gaataggttt
     7261 ggcttttaga aaggtcggaa tcgtaccaag tttattggaa atttctttat tactatagac
     7321 tccttcacca tctgtggtaa aatcaagaga agaaatccca aactcttggt aggggaaggt
     7381 atctttatca aaaacaccag acttgaccac ctcatcacca ctgtctgttt tgatgatgga
     7441 gactttatac tcctttgata catcctcaaa aaatcgaaga acagacgctg caggttcgtt
     7501 aatatctttc aaatacaaat ccaaagaatc tacagtcttt cccatttctt gaatccgaac
     7561 cacttctcgt gtatagttta cattaaaaac aaaaaaagtg gtacacagaa gcaggagtaa
     7621 catacagaaa ttactgattt ttttcataaa agtgcctcca ctacagtttt ccctctccaa
     7681 ataggagagg gaagaatttt actcaaatcc atagaaatat tccattcctg ttggcggaat
     7741 cttggtgagg gaagctctag cccatgcctc aggttttgca taatccttag aggttctacc
     7801 cccatgtcta acagttgctg tatgatatcg agtagaatgt aagtaatcag aatatccaaa
     7861 agttcctgtc caacctactc catagttcca ttgaccaccc tcaacccata ctgctaaagc
     7921 atttgtagta gcaagtatac cacataccat taaagatgca acaccaattt taactaattt
     7981 tctcatgatt tatttctcct attatcgaga gctgttccgt aaaaacagct atagtaattt
     8041 atcaacaagt atcgtagtcc attggactca ccttccttct atctcatttc attttttaac
     8101 aacgaactta ctcttaaccg ggagaatggt gcgcttctgt atcaggtcct tgaacaacca
     8161 gagtagtatt aagcacactc taactattac tcaagaatca gtccaataaa caatatggat
     8221 agcgctttca aatttttaaa ctcccatccc atccttttat ctatataata agtgaaaata
     8281 taataactgt caagtaatcg aagtgaattt tataaaaaaa attacaagcc aaatttgcaa
     8341 agtttacaat aagccgctag ggcaatcgtc tatcagaatg tccgtttatt tgtcaataat
     8401 ccgagaaaat cttgcaacgc ttagaagtct ataaaaacta tcaacattta tatgacttgc
     8461 gaatagcaat cctgctcaac ctttccacac tctatctata caatcaagat aaaaacatgt
     8521 gtaagcaaat ctgctacact ttactggagg acgccaagaa taagaaaagc tacgataggc
     8581 tggctatctg ctatgtccct attgggattt gtacagacga ttctaaactt atccaaaaag
     8641 ggttctccct tctggagcta accgaggaaa cttctatgct gtctcatctc aaaaaagaag
     8701 tagagatcta ttaccaagcg aaggaaagat aaaaaagccg agggatttcc tcgactcttt
     8761 acatattatt tgttcgttag ttcttaatac cagccattgt taagccagaa gtttttagca
     8821 gcagtccatg aaccgtaacg tcctgcaacg taggcatctg ctacacgttc ttggttttca
     8881 gctgagtagt caccgttcag gtatgaatct gttaattggt aacgtccgat ataacgtcca
     8941 tttgtagctg tatagctacc acctgattct ttttgagcga tccattcttt ggcttctgct
     9001 tcagatccgc ttacagttga aacaactgtt tcacttacta ctggagtttc tgctactgga
     9061 gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc tggtgttgca
     9121 acaggcgcta cagggccatc gataaccaac tcttgatcaa cataaatcaa atgaatgtta
     9181 tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc agcgatttct
     9241 gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga tacaaatgat
     9301 ggagcaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat ctttttagtt
     9361 attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc ctttaaatat
     9421 taccgtttct tgacactttt atgtagaaat attacaaaat tattttttat ttccctaaat
     9481 aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt agaaaggttt
     9541 tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa gaatttttat
     9601 aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat cggaccagtt
     9661 atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa gattgtctct
     9721 tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc atttgccaag
     9781 acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttggg aatgaataca
     9841 gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat caagattgtc
     9901 tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat tactgttaaa
     9961 aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa tattcaggta
    10021 accgaactca atggttttgc cgtctctctc aatatgaata caccgactat catcatcgtt
    10081 catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg ctatggtatc
    10141 aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat tatgattatc
    10201 gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat ccctcatctc
    10261 cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa gaattggtcg
    10321 agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca acagagtttg
    10381 aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat ctggaagtta
    10441 tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc ctgacaggtg
    10501 gagatgctgc caaattggat cactacatca aaaacgaaaa aactttatca gattacacga
    10561 ttctctctgc tgcccgaaat gctatcgcag tcaatgaaca caatgctaaa atgggcttgg
    10621 tctgcgctac tcctaccgca ggaagtgccg gttgtctccc ttccgttctc actgctgcta
    10681 ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct gctggtgcct
    10741 ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg tgtcaagctg
    10801 aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca ggtggaacac
    10861 cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc ctcatctgtg
    10921 accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg ggagctagct
    10981 ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc cctgtggatg
    11041 aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt cgtgaaacag
    11101 ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagag attttcggag
    11161 aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt ttcgatttgg
    11221 atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat acctttaaag
    11281 agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga ccacctctcg
    11341 aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccatg cagatatatc
    11401 gttcttacta taaggcaaaa ggcatctatg aagctcaact ctttcctcag attatagact
    11461 tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag aatacatcta
    11521 ctgctcaaga catggccaaa aacttggaaa tccatcattt ctttgatggt atttatggtt
    11581 ctagccctga agcaccccat aaggcagatg tcattcacca agccttacag acacatcaac
    11641 tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg ggagctcgag
    11701 aaacaggtat tcagaaattg gccgtcactt ggggatttgg agagcaagca gatctactaa
    11761 actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcatat tttcaatagc
    11821 atagactggg taacaattcc atttcagaag aaaatgaagt aatactcaat gaaaatcaaa
    11881 gagcaaacta ggaaactagc tgcgggctgc tctaaacact gttttaaggt tgtggataga
    11941 actgacgaag tcagtaacca tatacggcaa ggcgacgttg acgtggtttg aagagatttt
    12001 cgaagagtat aagtctctac ataataaaac gcatattacc aaggttgtgt aacttgatac
    12061 tatgcgtttt tcttttttat tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt
    12121 gcttcaactc atctccactg agagtgcgga actctccaat cttttgattg atggattcta
    12181 aaggcatgac attaacctta ccaacgaaaa tcttatccat aacttgatta tcaacaagtt
    12241 cggttgatac caagagttct tcgtagagtt tttcacctgg gcggattcca acttcaacga
    12301 ttggaatttc actttcagtg tggccactta gaagcaccat cttcttggcc aagtcataaa
    12361 tcttgactgg tttgcccata tcaaggataa agacttcccc atctttggca taagcaccag
    12421 catggataac cagacggcta gcttctggaa tggtcataaa gtaacgggtc atgcggaagt
    12481 ctgtcaccgt tacaggccca ccttcagcaa tctgacgttc aaagactgga atgacactac
    12541 cacggctacc aagaacattc ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt
    12601 taaagccagt gacaatcaac tccgccacgc gcttggttgc tcccataaca tttggtggat
    12661 taactgcctt atctgtcgaa atcataacca tcttagacac tttagcttca tcaacagcct
    12721 tagcaacatt gtaagttcca cggatattgt ttttgaaggc ttcttttgga ttgcgctcca
    12781 tcataggaac atgcttgtgg gctgccgcat gataaacaat agcaggtttg tactgctcaa
    12841 agacttgcaa caaacgatca tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc
    12901 cttggaactt acgaatcaat tcatgataaa caaggtagat tgagttttcc ccatgaccga
    12961 gcaagacaat gcgttcagga ttgaagcgac taacttgacg acagatttca gaaccgattg
    13021 aacctccagc tcctgtgact aagatggtct tacctgtcag ttctgcaccc agacgcgatt
    13081 cgtcaagacg gatttcctga cgacccaaaa ggtccgtaat atcaattttt tggaagccag
    13141 tacctgcttg gtgaaggccc tgaacaacag tttcaacctt aggcatcttg taacatttga
    13201 cacccagctt attacacatc tgcaagatac gctcatattc tgacggatcc agcgacggaa
    13261 tcgcaacgat gacacgctcg atttgatggc gtttggctaa ttcaggcaga ttgtcataag
    13321 agcccaaaac aggaatacca ccaagttttt gacccttttt cttagaatcc ttatccaaaa
    13381 taccgaccag ttctaattca ctggttggat gttggtaact atccataaag agagccccac
    13441 catcaccggc accaatcaag aaggtccgac ggtgttctcc atcaccacta ccttttttgc
    13501 gtctggagta gattaactgc caagtaatcc gtggcaataa aatcaagaag gtactcaaca
    13561 agataaagag aatgatgaaa cggatggaga agagtggcaa gaaggcataa cagatactat
    13621 atgacaagac actgctagca gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc
    13681 tgtaacgact aatgctcgcg ttcaatcccc aaaaaccaat catcaattga tagaacagga
    13741 aggccaaact cgtatagata atgtagtcaa caggtgctgg attaatcagc ccataaaata
    13801 aaatataaga tacaattatg gaaaccacca tactgaaaat atcaaatatt ccccagaaaa
    13861 cctgcttttg ttgtttattt aaaatttcca ccagatcaat cacataatct gttagttttt
    13921 tattcataga aatctactcc tccttaaaag agttttacta tattgttatt gtagcatatt
    13981 ttgatttatt tggcttattt tatccaaata aattattgtt cccttgtact ccttcttcca
    14041 tttaaatcct ctaattaaac ctacaatcgt cccaaagcca taagcaaagt gaatggaaaa
    14101 taaaagaaag ggcatcacaa ttagaaatcc atttttatgt tttaataaag tcagcaaagt
    14161 gagtagtgac aaaagtagaa aataggcacc taatagtaaa gttatgaata cgaatgtgat
    14221 cggtaacaat gctagactaa acacaagact caaaacaaat aaacaaggaa catagtgaaa
    14281 taatgataaa cacttaaact gaacatgact tgtcaagcca atccacaaac catttaaata
    14341 cttttgatgc agcattttct tgaatgttgg tcgaatatac tgataagata gaatacttgg
    14401 gctatagcgg attttataac catattctcg aattctataa tgaatatcat tatcttcagt
    14461 tcggccaagt tgctcattta ctaaaccaac cttctggaaa acctctcgtt tatacattcc
    14521 atgaaaaata gaagaaacat atctatcctc agaactattt cgataattgg caatgctact
    14581 gccaaacata ttttcctcaa caagatgcaa ggtctctgcc cattttcctt ttccttcgac
    14641 aatcgtcggt ctaggccccc cacagacaaa ttcaccttgt tgaataatag ccacattgtt
    14701 cattacaaaa gtctcagtaa cttttgaatg agcatcaatt tttaaaataa ggtcccctac
    14761 agaatgttta actcccaggt taaaaccact agcttgattt ttcttaggat tgttatacaa
    14821 tctaattgag ttaaactctg tatcttcctt tataaattgc tgaatgatag ctgtggtccc
    14881 atctgtggac atagcattta taaatagaat ttcaatattc tctttaggat aggtttgatt
    14941 ttttaagtct tcaattagac caggcagata tttttcttca ttgtatgcac tgattacaat
    15001 ggatacgaga agactttcaa cattttgagt cactactact ctcctgaatt tttccttcca
    15061 ccattctatc ataattttca agactttccc atttttatct tgaaagccag aaaccttact
    15121 tgacattata gtgaaaaagc cttaaaataa gctgttatta aaatcagcta gaagaggtat
    15181 tatatgaaaa agcaatcact cttttttgtt ccaggtatta tcctgattgg tgtttccttg
    15241 cgaactcctt ttactgtttt acccattatt ttgggaaata tttcgcaagg tctggaggta
    15301 gaagttagtt cgcttggtgt cttgaccagc ctgcctctcc ttatgtttac cctcttttca
    15361 ccattttcta cccaactggc tcagaaaatc ggcttggagc atctcttcac ctacagcctc
    15421 ttcttcttga ccatcggctc acttattcga ctaatcaatc tgcccctgct ctatctagga
    15481 accttgatgg ttggggcaag tgtcgcagtc atcaatgtcc tgcttcctag tcttatccaa
    15541 gccaatcaac caaagaaaat tggttttctg accaccttat atgtaacgtc tatggggatt
    15601 gcaacggctc tggcttccta tctagctgtg cccattacac aagccagttc ttggaaagga
    15661 cttatccttc tcctcacgtt actctgtcta gcaacttttt tggtctggct cccaaatcac
    15721 cgctataatc atagactagc tccacaaacc aaacaaaaaa gtcaaataaa ggtcatgcgt
    15781 aataaacagg tttgggcaat tattatcttt tcaggttttc aatccttgat cttttacacc
    15841 gtcatgacct ggttacctac catgtctatc catgcaggtc tatccagtca cgaagctggc
    15901 ttgctgactt ctatcttatc tctgattagc attccttttt caatgaccat cccaagcctg
    15961 acaaccagtt tatctactcg caaccgtcag ctcatgctca ctctggtttc actagctggt
    16021 gtggtcggca tttccatgct ctttttccca atcaataatt tcatttactg gcttgccatc
    16081 catctcctca tcggaaccgc aaccagtgcc ctcttccctt atctcatggt caacttttca
    16141 ctcaagacaa gcgcccctga aaagacagcc caattgtccg gcctatctca aacaggaggc
    16201 tatatcctag cagcctttgg gccaaccctc tttggttaca gttttgacct gttccactct
    16261 tgggtaccat ctgtagctgc cctcttgctc atcgatatcc tgatgactgt ggccctcttt
    16321 acagtggaca gagcggataa gatcctttaa acttctagtt ttagctagaa gttttttata
    16381 tataaaaatt ttacacattt ctcttgacag ggctttcttt tagatgtaca atgtatgtgt
    16441 agaaaaatta tatataaaaa tcttacacat tagaaaagga ggtttcccat gtactttcca
    16501 acatcctctg ccttgattga atttctcatc ttggctgtac tggagcaggg tgattcttat
    16561 ggttatgaga ttagccaaac cattaagctg atcgctaata tcaaagaatc cacactctat
    16621 cccattctca aaaaattgga aggcaatagc tttctgacaa cctattctag agagttccaa
    16681 ggtcgcatgc gcaaatacta ctccttgaca aacggtggta tagagcagct cttgacccta
    16741 aaagatgaat gggcactcta tacagacacc atcaatggca tcatagaagg gagtatccgc
    16801 catgacaaga actgaatacc tgactcagct agaactctat ctcaagaaac tacctgaagc
    16861 tgaccgtatc gaagccatgg actatttcag agagctcttt gacgatgctg gagtcgaagg
    16921 agaagaagaa ctcatcgcta gtttgggaac tcccaaagaa gcggcccacg aagttctatc
    16981 caatcttctc gataaaaaaa tcaatgaagc acccgctcaa aaaaataacc gacaaatttt
    17041 acatatcgcc ttgttagccc tccttgcagc acctatcggc attcctctgg gaattgccat
    17101 cctcgtgacc ctgttcgcaa ttcttgtagc cgctttgact gtcattctgg ctttctttgc
    17161 agtttccata ctgggtatca tcggcggatt cctattttta gttgaaagtt tcactgtcct
    17221 cgcccaagcc aaatcagcct ttatcttgat ttttggttct ggtttactgg ctatcggtgc
    17281 ttcttcgcta gttttacttg gcatttccta tgtaactcgc ttcttcggtc tactcattgt
    17341 tcgtctggta caatttgttc ttaaaaaagg aaagagaggt aatcagcatg cgtaaatgga
    17401 caaaaggatt tctcatcttt ggtgtggcga ctaccgttat cggctttatc ctgctttttg
    17461 taggtatcca atctgacggg attaagagcc tactttccat gtccaaagaa cctgtctatg
    17521 atagccgtac ggaaaagcta acctttggca aggaagtcga aaacctagaa attactctcc
    17581 accaacacgc gctcaccatc acagactctt tcgatgatca aatccacatt tcttaccatc
    17641 catctctttc tgctaaccat gatcttatca caaatcaaaa cgatagaact ctgagtctca
    17701 ctgataagaa actgtctgaa actccgtttc tctcttctgg aattggtggg attcttcata
    17761 tcgcaagtag ctactctagt cgttttgaag aagttattct ccagctacca aaagggagaa
    17821 ctctaaaagg gatcaacatc tcagccaatc gcggacaaac caccatcata aatgctagcc
    17881 ttgaaaatgc gaccctcaat acaaacagct atatcctccg aattgaagga agtcgtatca
    17941 aaaacagtaa actcacaacg cccaatatcg ttaatatctt tgatacagtt cttacagata
    18001 gtcagctaga gtcaacagag aatcacttcc acgctgaaaa tatccaagtc catggcaagg
    18061 ttgaactgac tgccaaagat tatctcagaa tcatcctaga ccagaaagaa agccaacgaa
    18121 ttaactggga catctcaagc aactatggtt ctatcttcca attcacaaga gaaaagcctg
    18181 aatcaagagg tacggaatta agcaaccctt acaaaactga aaaaaccgat gtcaaggatc
    18241 aactcattgc gagatctgat gataatattg atctaatatc cacaccaagc agacgttgac
    18301 aaaaacgctt acatttgcta ctatggaaac atatttatct aactaaaaag gaggttctac
    18361 catgaaacaa gaatggtttg aaagtaatga ttttgtaaaa acaacaagca agaacaagcc
    18421 tgaagagcga gctcaagagg ttgcagacaa ggctgaagaa acgatagcca atctcgatac
    18481 accaattgga aaaaatactc aagtagagga ggaagtctct caagctgaag tcgaactgga
    18541 aagccaacaa gaagagaaaa ttgaagctcc tgaagacagt gaagcgagaa caggaataga
    18601 agaaaagaag gcatctaatt ctactgaaga agagccagac ctttctaaag aaacagaaaa
    18661 agtcactata gctgaagaga gccaagaagc tcttcctcag caaaaagcaa ccacgaaaga
    18721 gccacttctt atcagtaaat ctttagaaag tccttatatc cccgaccaag ctccaaaatc
    18781 tagggataaa tggaaagagc aagtgcttga tttttggtct tggctagtgg aagcgatcaa
    18841 atctcctaca agtaagttgg aaacaagtat cacacacagt tacacagcct ttctcttgct
    18901 cattctgttt tctgcatctt cctttttctt tagtatctat cacatcaaac atgcttacta
    18961 tggacatata gcaagcatta acagtcgctt ccctgagcag ctagctcctt taactctttt
    19021 ttctatcatc tctaccctag tagcgacaac actcttcttc ttttcattcc tcttgggtag
    19081 tttcgttgtg agacgattta tccaccagga aaaggactgg acgctagaca aggttctcca
    19141 acaatatagt caactcttgg caattccaat cttcctcact gctattgcta gtttctttgc
    19201 tttctttgat agcctacgat ttacagctct cttgtgtgtg attagcattg gaatcattct
    19261 gcttgccagt ctccatatca ttacaagacc aagtcaagca agtgaaaccg actccttcta
    19321 tcaattattc ttgtctgtcc ttgtgaacgg agttattatc ctcctcttct ttgtagctga
    19381 agtggcactg attggagatt atcttcgtat cttggccttt ctttaaaatt caatcctgtc
    19441 atccttggca ggatttttct atttcaaaaa agcaagtcga ttgacctgct tctgctttac
    19501 ttttcttgtg ctaatgtttt aaaatcttgt cctaggatgg gttgtacttc taattgattg
    19561 gcgtctagtt ggtggtaaaa tgctgatggt agtgactcta ggaattttgc atagtccaag
    19621 cgggcgatgg cttcatagtc ttctggttta gagccatctc ctgtgatttg aaccaagtcg
    19681 atctcccact ggacttcctt atccaccaat tgctcaatat aggctgcagg aacaaacggt
    19741 tctctcggta aaactgtctt gactccttga gctagatggt aaacgccatg cacttttcct
    19801 tctccatcct gatagaagga aactctcgca aagtaggcat ctgtctcttg aaccgcacgc
    19861 acacgcgctt caaactgagc caagccatct gcctctaaaa agcttttcaa gttctcacga
    19921 ctaaagaaaa taggattaaa aattccttgg caaatcgtaa aacgagctac agggtctgct
    19981 agataggctt gaatacttgc ttggaaataa gcttcaaaat caaaaccatc tagcccttca
    20041 atatcagtcc ctgtataagc aagcaaagca tctaaaaatg acttgataat ctgccagtct
    20101 gtctttgtta gtaggtcagg aagatcgaca cggtaagcct tttgaccatc agcataactg
    20161 accttaaaga gaaattgtga ttgccccact atcgcacact cgatatattc gagacgatta
    20221 agaggctgac ggagatagac tacatcatag ctatgtgact ccaaaccgtc tagcaaggcc
    20281 aagatcgact tggcattcaa aatttcttgt tctcctaaaa tgctctgttt atttggaata
    20341 aaaaatgttt tcgccataac tggactcctt tgaaatcgtt tacatacagt ataccttatt
    20401 tttctgaaag atacaaaaac aaactttata ctcttcgaaa atctcttcaa accgcgtcag
    20461 cttcgccttg ccgtagatat atgtaactga cttcgtcagt cttatctaca acctcaaagc
    20521 agtgctttga gcagcctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt
    20581 agatttttga gtacaaagca tagaaaaaca gcccctgagg actgtttgat cttatacagt
    20641 agctgcttga tccaagcttt caccgatagc ggctaggcgc tcgatcactt cagcttgtgt
    20701 caattcattt tttgaaacat agcggttacg tgggtgaaca cggcactcgt gtgagcatcc
    20761 acgaaggtac ttgtcttcat tttcttctga tgtcaagata cgacggttac agaatggatt
    20821 tccacagttg acataacgtt cacatggtgt tccatcaaac cagtctttcc ctacgatagt
    20881 tgggttgaca tggttgacat caacggcaat acgctcgtca aagacgtaca ttttcccatc
    20941 ccaaagctca ccttgaactt ctgggtcttt accgtaagtt gcgattcctc cgtgcaattg
    21001 gccaacatct ttgtaacctt cacggaccat ccagcctgag aatttctcac agcgaacgcc
    21061 acctgtacag taaaccacga cacgcttgtc catgaatttt tccttgttat cacggaccca
    21121 ttgtggtaac tcacggaagt tgcgaatatc tgggcgaata gccccacgga aatgtcctag
    21181 atcgtactca taatcgttac gtgtgtcaag gacaacggta tctttatcaa gaagcgcttc
    21241 tttgaactct tttggagaca agtaagcacc tgttgtttca agtgggttga tgtcattgtc
    21301 aaagtcgttg tcttccaaac caaggtggac aatttctttc ttgtagcgaa caaacatctt
    21361 cttgaaggct tgttcatttt cttcgtcaat cttgaaccag agatcttcca tacctgggag
    21421 gctgtgaacg tagtccatgt atttttgagt tgtttcatag tcacctgaaa ctgttccgtt
    21481 aattccctcg tcagcgacta ggatacggcc tttaaggccg attgatttac agaaagccaa
    21541 gtggtctgca gcaaattgct ctgcattttc aattggagta taaaggtagt aaagtaagac
    21601 acgaatatct tttgccataa gatttgttct cttttctatt cttaaatttt ctaaattttt
    21661 tatttatcca tactagtata cctgcttgag aaaacgaatg caatttattt gactggaaat
    21721 tgtagaggat tctcgaaatt tcctgaatgg ttaaaataag gacaagagaa aacagggata
    21781 tctatatcct tgtgccaaaa aaaccactgc cctccccaga ccaacctgag gaaagcagtg
    21841 attcttattt taggagttag gaatgaatac acgaaatcaa tttagctgat tattttttgt
    21901 ttttcaagaa ttcatcgtat tgtttttgca tttcgttcaa tactttttcg taggcacctt
    21961 cagatttcaa tttttccatc aattctggaa tcgctttatc tgggtctaca gtaccagtgt
    22021 tgatagctgt atcaaattgt tgcattgtgt tagcaatagc tgagatttca gatttcacat
    22081 tgtcagtatt aaagataaat ccaagcgctg gagattcttt agcttctgcc aattctttct
    22141 tagaattttc gatttgttgg tctgtaacgt tttcgttgat gtaaaggatc cagttgttac
    22201 cagtgttcca tccacccatg tgagtgtttc ctttgtagcc atcaagaacg cgaacacgat
    22261 tttctttacc ttcaattttt tcccagttct tgccttctgg accgtaaaca agaccgttca
    22321 agagttctgg gttcgtattc aagaggttca acacttccat tgatttttct ttgttcttag
    22381 agttgtttga gatgacaaag ttagcaactt gtgttgtttg gtttttcttg atgaagttag
    22441 taattggttt gatttggata tctttgttgg caacacgtga aagcaagctg ttaccgtagt
    22501 cagctggtcc tactgtttct tcacgaacga accaagtatc ttgttgaagg tcaaatgaag
    22561 tatcgcttgt tgcgacatct tttggaatgt agccagcttc atagaatttg tgaagagtct
    22621 tcaagtgttc tttgaaacga ggcacttcgt aacggtttac aactttagta gtatcgcctt
    22681 caagatcaat aacgaatgga agcccgtttg ctactgggta gtcaaagtta tcagatggga
    22741 tgaaaacttt accaatagca aatggtacta cgtctggagc tttttcttta atttgtttca
    22801 agactggctc aagagtttcg taagaagtaa cacctgaaat atcgatacca tatttggcaa
    22861 ggagagttcc gttgaaggca aagttttgag atgatgcaac gttggctgca actggaacag
    22921 cgtaaatttt accgtttaca gtattaccct tgatgtaagc tgggtcaagt gccttgtaaa
    22981 ggtctttacc ttcttttttg tacaattctg tcaagtcagc ataagcacct ttttgagcat
    23041 ttacaatata gttatctgca aaggcgatat catagttttc accagatgat gtgataactg
    23101 acattttctt accatagtca ccccagccaa ggtattggat atccaatttg gcaccaactt
    23161 tttcttcgat gattttgttg gcatttgcta acaattcatc caagttatct ggtttgtcac
    23221 cgatttggta cattttgata acaggtttgt cacctgaatc agcagctttt ttgctgttac
    23281 ctgtcaaatt tccacaagca gcaagacctg cagccaaagc gactacacta gcagatgcaa
    23341 aagcatattt tttccagttt ttcatgataa aaactccttt ttttattttt aaacttataa
    23401 acaatgtaat gatcttaact tcacgcaagg gaagtttgga aacaagtgct attctttcac
    23461 accaccgata gtcaaacctt ttacaaagta gcgttggaaa aatggataca aaatcgcgat
    23521 tggaagggtt gcaaccacaa ccatggccat acgacctgtt tctttcggta gagcaactcc
    23581 cagttgacca gtcaagccga ccgctttggc aatgtagtcc atattttgtt ggatttgcat
    23641 gagcaaatat tgcaatggat acaagttgtc actcttgatg taaagaaggg cgttgaacca
    23701 gtcattccag aaaccaagag ctgttaagag cgtgatggtt gcgatacctg gtagtgacaa
    23761 tggcaaacag atttggaaga aaatccgggc ttcactggca ccatcgatac gagccgattc
    23821 tagaatggct tctggaatgg tcttcttgaa gaaggaacgc atcaagatga tgttaaatgg
    23881 tgagagaagc attggaacaa tcaaggccca aacagtatcc ccaagctgaa gtacacgggt
    23941 caccatgata taacctggta ccaaaccagc gttgaacaac atactgagaa ggacgaagat
    24001 ggtaaaaaat ctgcgatact taaaggttgt ccgtgaaata gcgtaggcat aggttgttgt
    24061 gataaagaca tttgtcaatg tcccaactac ggttacaaag acagagatga agagggcttg
    24121 taggatttta tccttaaact gtgccaaaaa ctcaaaaccg tctaagccaa attgggatgg
    24181 gaagaagcta tagccgtatt ggaggaggct tttctcgtct gtcactgaaa taatgataac
    24241 gaatacaaaa ggtaggatac aagagagggc aatcaaaccc gaaatgatac tgaagaagat
    24301 atctgctttc ttactgaagg agtgaatgcc gacattatca attttttctt ttttaatttt
    24361 cttttttgcc atattctcct cctttctaga acaaagctga gtttggatcg actcgtcttg
    24421 caagcaagtt tgataggata accagaatca aaccaacaac ggattggtaa agaccggctg
    24481 ctgcagccat accgatatct gctgtctgag tcaaaccatt aaagacatat acgtccaaaa
    24541 cgttggttac attgtaaagc tgaccagcat tgtgtgggat ttgatagaag agaccgaagt
    24601 ctgcgcggaa gatatttccg actgcaagga tggtcaatac agttacaagc ggagtcaact
    24661 gaggaatggt tacgttgcga atacgttgcc acttgctagc tccgtccact gtcgctgctt
    24721 cgtagtaggt tggatcaatt cccatgatcg tcgcatagta catgacactg ctatatccaa
    24781 agcctttcca aatacctagg aaaagtagga gatagggcca gatgcccagg tcagcgtaaa
    24841 aattgacttc tttgagacca agactttcca atagatgatt gaacacccct ttatcaatat
    24901 ttaggaaggc atctgtaaag aaactgatga taacccaaga caagaagtaa gggaacaaca
    24961 tagaagtttg gaaaatcttc accattctct tagaacggag ctcgctgagg ataatggcaa
    25021 tccctacaga tacaactaaa cctagaaaga taaagccaag actgtagagg acagtatttc
    25081 gtgtgataat aaaggcgtct cttgaactaa ataagaatct gaaattatcg agtccgaccc
    25141 atttactatt tatgatacta tctatgaaac cattactggt catgtggtag tctttgaagg
    25201 caaccacgtt cccaaatact ggaatgtaaa agaatagaat caaccagagt gcccctggca
    25261 aaaccatcaa gagaaagatc cagttgtctc tcaatgtttt tgaaaacttt ttcataattt
    25321 cctccctttt tattttgata tccatctaaa aattcttttt tagacttttg ataacgatta
    25381 cattattagt atactcctat ttgtaggtta ggttaaactc ctaattatag aaaaaactcc
    25441 acaaattatg tagcagattt aaaactttat caccactatc aaacaaatgt cctaaatcaa
    25501 ttgtttattt tatctctatt agcccagtga tggcgtcact ctgttataaa catccaacaa
    25561 cgggggatac tgaaaaatct ccagactagg gaactcagcg atagttccta atctggagat
    25621 ttttaatatg ttattaggcg tttgctttca acttagcaat aacctcttta agattatcaa
    25681 tcacctctgc ttcagtatgc tcagagcctt tttcatctgc caagaacaaa actgcttttt
    25741 gaagttcttt ttgagagttt tcaaggacat ccttatctac tgtttcaagg tttgagtctt
    25801 taagaagttt acttaattcc ttggctaatt tcttgagttt gatttgcaga ctcatcttct
    25861 cctgctgttt ctttgcccgc tgtttgtcct ccatccttag ttgctgactg gctttcctta
    25921 atggactcta gggaagcaat ggcatctttg actgtttgca agatatcacg taaaccttgc
    25981 tctgtcaaac tatcatctgc aaaagctttc ttagcctctg ccaaaaccag acgtgctgaa
    26041 tctgtggtag gattcgatac acctgtcaat gatctcaaaa gattttctaa ggtttgagtc
    26101 tgcttactaa tactagacta aaatcaaaaa gtattatata acagtgatat gaaatcaa
//
LOCUS       DAVMCN010000021        25095 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVMCN010000021 DAVMCN010000000
VERSION     DAVMCN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.021"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(216..303)
                     /locus_tag="VYP85_001088"
     tRNA            complement(216..303)
                     /locus_tag="VYP85_001088"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(267..269),aa:Ser,seq:gga)
     gene            465..1205
                     /locus_tag="VYP85_001089"
     CDS             465..1205
                     /locus_tag="VYP85_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1881619.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1202..2113
                     /gene="pfkB"
                     /locus_tag="VYP85_001090"
     CDS             1202..2113
                     /gene="pfkB"
                     /locus_tag="VYP85_001090"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1881620.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVKLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            2110..4062
                     /locus_tag="VYP85_001091"
     CDS             2110..4062
                     /locus_tag="VYP85_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1881621.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLTGHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALTELSQYLMKDGFADKLRQATSADQVVELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAVDKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDAEVYRAANGAK
                     AATVSNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4226..6451
                     /locus_tag="VYP85_001092"
     CDS             4226..6451
                     /locus_tag="VYP85_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1881622.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(6496..6924)
                     /locus_tag="VYP85_001093"
     CDS             complement(6496..6924)
                     /locus_tag="VYP85_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881623.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            7087..9171
                     /locus_tag="VYP85_001094"
     CDS             7087..9171
                     /locus_tag="VYP85_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1881624.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKISALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GGLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            9181..9558
                     /locus_tag="VYP85_001095"
     CDS             9181..9558
                     /locus_tag="VYP85_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881625.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            9718..10860
                     /locus_tag="VYP85_001096"
     CDS             9718..10860
                     /locus_tag="VYP85_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1881626.1"
                     /translation="MIYFDNSATTSPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            10869..12083
                     /gene="thiI"
                     /locus_tag="VYP85_001097"
     CDS             10869..12083
                     /gene="thiI"
                     /locus_tag="VYP85_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1881627.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            12218..13031
                     /locus_tag="VYP85_001098"
                     /pseudo
     CDS             12218..13031
                     /locus_tag="VYP85_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            13053..13388
                     /locus_tag="VYP85_001099"
     CDS             13053..13388
                     /locus_tag="VYP85_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV1881628.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            13385..13792
                     /locus_tag="VYP85_001100"
     CDS             13385..13792
                     /locus_tag="VYP85_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1881629.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            13805..14971
                     /locus_tag="VYP85_001101"
     CDS             13805..14971
                     /locus_tag="VYP85_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1881630.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(15462..17132)
                     /locus_tag="VYP85_001102"
     CDS             complement(15462..17132)
                     /locus_tag="VYP85_001102"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1881631.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVDAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWGKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            17362..18051
                     /gene="coaB"
                     /locus_tag="VYP85_001103"
     CDS             17362..18051
                     /gene="coaB"
                     /locus_tag="VYP85_001103"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1881632.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDILIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            18063..18614
                     /gene="coaC"
                     /locus_tag="VYP85_001104"
     CDS             18063..18614
                     /gene="coaC"
                     /locus_tag="VYP85_001104"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1881633.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            18598..19161
                     /locus_tag="VYP85_001105"
     CDS             18598..19161
                     /locus_tag="VYP85_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1881634.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGITLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            19443..19970
                     /locus_tag="VYP85_001106"
     CDS             19443..19970
                     /locus_tag="VYP85_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1881635.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            19982..20497
                     /locus_tag="VYP85_001107"
     CDS             19982..20497
                     /locus_tag="VYP85_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1881636.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(20494..20961)
                     /locus_tag="VYP85_001108"
     CDS             complement(20494..20961)
                     /locus_tag="VYP85_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1881637.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(21034..21522)
                     /locus_tag="VYP85_001109"
     CDS             complement(21034..21522)
                     /locus_tag="VYP85_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881638.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(21488..22051)
                     /locus_tag="VYP85_001110"
     CDS             complement(21488..22051)
                     /locus_tag="VYP85_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881639.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            complement(22061..24049)
                     /gene="uvrB"
                     /locus_tag="VYP85_001111"
     CDS             complement(22061..24049)
                     /gene="uvrB"
                     /locus_tag="VYP85_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1881640.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(24126..25079)
                     /locus_tag="VYP85_001112"
     CDS             complement(24126..25079)
                     /locus_tag="VYP85_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1881641.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
BASE COUNT         7467 a         5040 c         5134 g         7454 t
ORIGIN      
        1 aagaaactgg attaattaaa cttgaagtat ttgagatttt gtcttttact gttcgtaaaa
       61 tcgtatgaga taagaaggga gtggaaagaa ttcatactct ctctagaact tgtatattga
      121 aacgatgtgg agattgtaaa gaaattacaa aataccccaa aactaagata gaaatacaaa
      181 gtttcagggt atcatatatt ttatctgttt ttccacggaa gacatgggat tcgaacccac
      241 gcacgctatt acacgcctac cgcgtttcca acacggcctc ttaagcctct tgagtaatct
      301 tccaatactt actcaaatag tctaccataa aggctcttat cttgcaataa aaattctaga
      361 aataagaaaa atgatagatt ttgaaagaaa atgataaaaa atgcttgact tcaaaagaaa
      421 gtatggtaga atgaatagtg taaacgataa caggaggtga ttcagtgtta aaaacagaac
      481 gtaaacaact gattttagag gagttaaatc aacatcatgt agtttctcta gaaaaattag
      541 ttagtttgct agaaacgtca gaatcaacgg ttcgaagaga cttggatgag ttggaagcgg
      601 aaaacaagct tcgtcgtgtg catggtggag cagaactccc ccactcctta caggaagaag
      661 aaaccattca agaaaaatct gtcaaaaacc ttcaagaaaa gaaattgctg gctcagaaag
      721 cagcctctct cattaaagaa aaagatgtca tctttatcga tgctggaaca acaactgctt
      781 ttttgattca tgaattggtc aataagaatg ttacagttgt gaccaactcc attcaccatg
      841 ccgctcagtt ggttgaaaag cagattccaa ctgtcatggt tggaggaaac gtcaagacgg
      901 cgacagatgc tagtatcggg ggcgttgctc ttaaccagat taaccaattg cactttgacc
      961 gtgcctttat cggaatgaat ggtgttgacg atggctatta tacgactcct gatatggagg
     1021 agggagctgt gaaaagagct attttggaga atgccaagca gacctacgtc ttggtggatt
     1081 cgtcaaaaat tggacaaact tgctttgcca aggtagcccc actcaaacgc gctatcgtta
     1141 tcactagtca agggcatgag ctcttgcagg ttattaagga gaaaacggag gtaatagaag
     1201 tatgatttat acagtcacac tcaatccatc cattgactat atcgttcgtt tggaccaagt
     1261 caaagttggt agtgtaaatc gtatggacag tgatgataag tttgctggtg ggaaaggaat
     1321 caatgtcagc cgtgtcttga aacgtttgaa tataccaaat acagcgacgg gatttatcgg
     1381 tggctttact ggtaaattta tcacagatac tttagcagag gaagaaatcg agacacgttt
     1441 tgtccaggtg gcagaagata ctcgtatcaa tgttaaaatc aaagcagacc aagaaacaga
     1501 aatcaacgga acgggtccaa ctgttgaacc ggttaagcta gaagaattga aagctatttt
     1561 atctagtctg acagcagaag atacagttgt ctttgcaggt tcaagtgcta aaaatctagg
     1621 caatgttatc tataaggatt tgatttcctt gacgcgccag actggtgcgc aagtggtctg
     1681 tgactttgaa ggacagacct taattgatag tttggactac cagcctcttc ttgtaaaacc
     1741 aaacaatcat gaacttggag cgatttttgg ggttaaactc gaaagtttag atgaaattga
     1801 gaaatacgct cgtgagttac tggctaaggg tgctcaaaat gttattatct ctatggctgg
     1861 tgatggtgcc cttcttgtca catctgaggg agcttacttc gctaaaccaa tcaaaggaac
     1921 agtcaaaaat tcagttggag ctggtgattc tatggttgct ggattcacag gtgaatttgt
     1981 caaatcaaaa gacgcagtag aagccttcaa atggggagtg gcttgcggaa cggcaactac
     2041 cttctcagat gacttggcaa cggcggaatt tattaaagaa acatatggaa aagttgaggt
     2101 agaaaaacga tgaaaattca agatttattg agaaaagatg tcatgttgct ggatttgcag
     2161 gcaactgaaa agactgctgt cattgaagag atgattaaaa gcctaacagg ccacggttat
     2221 gtgacagatt ttgaaacatt taaagaagga attttggcgc gtgaagcttt gacttctact
     2281 ggtttgggtg atggaatcgc aatgcctcac agcaaaaacg ctgctgtcaa agaagcgaca
     2341 gttctctttg ctaagtcaaa caagggtgtt gactatgaga gtttggatgg gcaggcaact
     2401 gacctcttct tcatgattgc agctccagaa ggtgccaatg atactcactt ggcagcattg
     2461 acagaattgt ctcaatactt gatgaaagac ggttttgcag acaaacttcg tcaagcaaca
     2521 tctgcagacc aagttgtcga actttttgac caagcttcag aaaaaactga ggaacttgtt
     2581 caagcacctg ctaatgactc tggtgacttt atcgtagctg ttacagcttg tacaacaggt
     2641 attgcccaca cttacatggc ccaagaagcc cttcaaaaag tagctgctga aatgggggtt
     2701 ggtatcaagg tcgaaaccaa cggtgctagc ggtgttggaa atcaactaac tgcagaagat
     2761 atccgtaagg ctaaagctat tatcattgca gtagacaagg ccgttgaaat ggatcgattt
     2821 gatggaaaac cattgatcaa tcgtccagtt gctgacggta tccgtaagac agaagagtta
     2881 attaacttgg ctctttcagg agatgcggaa gtctaccgtg ctgctaatgg tgcaaaagct
     2941 gcaacagtct ctaacgaaaa acaaagcctt ggtggtgcct tctacaaaca cttgatgagt
     3001 ggtgtatctc aaatgttacc attcgttatc ggtggtggta tcatgattgc ccttgccttc
     3061 ttgattgacg gtgctttggg tgttccaaat gaaaaccttg gcaatcttgg ttcttaccat
     3121 gagttagctt ctatgttcat gaaaattggt ggagctgcct ttggtttgat gcttccagtc
     3181 tttgcgggtt atgttgccta ctctattgct gaaaaaccag gtttggtagc aggtttcgtg
     3241 gctggtgcta ttgccaaaga aggttttgcc tttggtaaaa ttccttatgc cgcaggtggt
     3301 gaagcaactt caactcttgc aggtgtctca tctggtttcc taggtgccct tgttggtgga
     3361 tttatcgcag gtgccttggt tcttgccatc aagaaatacg ttaaagttcc tcgttcactc
     3421 gaaggtgcta aatcaatcct tctattgcca cttcttggaa caatcttgac aggatttgtt
     3481 atgctagctg taaatatccc aatggctgca atcaacactg ctatgaatga cttcctaggc
     3541 ggtcttggag gaggttcagc tgtccttctt ggtatcgtcc ttggtggaat gatggctgtt
     3601 gatatgggtg gaccagttaa taaagcagct tatgtctttg gtacaggtac gcttgcagca
     3661 actgtttctt caggtggttc tgtagccatg gcagcagtta tggctggagg aatggtgcca
     3721 ccacttgcaa tctttgtcgc aactcttctt ttcaaagata aatttactaa ggaagaacgt
     3781 aactctggtt tgacaaacat catcatgggc ttgtcattta tcactgaggg agcgattcca
     3841 tttggtgccg ctgacccagc tcgtgcgatt ccaagcttca tccttggttc agcagtagca
     3901 ggtggactcg ttggtcttac tggtatcaaa ctcatggcgc cacacggagg aatcttcgtt
     3961 atcgccctta cttcaaatgc tctcctttac ctcgtttctg tcttggtagg agcaatcgta
     4021 agtggtgtgg tttatggtta cctacgcaaa ccacaagcat aaaaaataga aaaatgaaaa
     4081 gattggaccg tttggtgcag tctttttctc ttcccgaaat gcctgtgaaa tatggtataa
     4141 tagaagaatg gcaaacaaga atacaagtac aacaagacgg agaccgtcta aagcagaact
     4201 ggaaagaaaa gaagcgattc aacgaatgtt gatttcatta ggaattgcga ttttattgat
     4261 tttcgcagcc ttcaaattag gggctgcagg tataaccctt tataatttaa ttcgcttgct
     4321 agtgggtagc ctagcttatc tggcgatatt cggcctatta atctatctct tctttttcaa
     4381 gtggatacga aaacaggaag gactcttatc tggctttttc accatatttg ctggcttact
     4441 cttgattttt gaagcctact tggtttggaa atatggtttg gacaagtccg ttctaaaagg
     4501 gaccatggct caggttgtga cagatctgac tggttttcga acgactagct ttgctggagg
     4561 gggcttgata ggggtcgctc tttatattcc aacagccttt ctcttttcaa atatcggaac
     4621 ttactttatt ggttctatct tgattttagt gggttctctc ctagtcagcc cttggtctgt
     4681 ttacgatatt gctgaatttt tcagtagagg ctttgccaaa tggtgggaag ggcacgagcg
     4741 tcgaaaagag gaacgctttg tcaaacaaga agaaaaagct cgccaaaagg ctgagaaaga
     4801 ggctagatta gaacaagaag agactgaaaa agccttactc gatttgcctc ctgttgatat
     4861 ggaaacgggt gaaattctga cagaggaagc tgttcaaaat cttccaccta ttccagaaga
     4921 aaagtgggtg gaaccagaaa tcatcctgcc tcaagctgaa cttaaattcc ctgaacagga
     4981 agatgactca gatgacgaag atgttcaggt cgatttttca gccaaagaag cccttgaata
     5041 caaacttcca agcttacaac tctttgcacc agataaacca aaagatcagt ctaaagagaa
     5101 gaaaattgtc agagaaaata tcaaaatctt agaagcaacc tttgctagct ttggtattaa
     5161 ggtaacagtt gaacgggccg aaattgggcc atcagtgacc aagtatgaag tcaagccggc
     5221 tgttggtgta agggtcaacc gcatttccaa tctatcagat gacctcgctc tagccttggc
     5281 tgccaaagat gtccggattg aagcaccaat ccctgggaaa tccctaatcg gaattgaagt
     5341 gcccaactcc gatattgcca ctgtatcttt ccgagaacta tgggaacaat cgcaaacgaa
     5401 agcagaaaat ttcttggaaa ttcctttagg gaaggctgtt aatggaaccg caagagcttt
     5461 tgacctttct aaaatgcccc acttgctagt tgcaggttca acgggttcag ggaagtcagt
     5521 agcagttaac ggcattattg ctagcattct catgaaggcg agaccagatc aagttaaatt
     5581 tatgatggtc gatcccaaga tggttgagtt atctgtttac aatgatattc cccacctctt
     5641 gattccagtc gtgaccaatc cacgcaaagc cagcaaggct ctgcaaaagg ttgtggatga
     5701 aatggaaaac cgttatgaac tctttgccaa ggtgggagtt cggaatattg caggttttaa
     5761 tgccaaggta gaagagttca attcccagtc tgagtacaag caaattccgc taccattcat
     5821 tgtcgtgatt gtggatgagt tggctgacct catgatggtg gccagcaagg aagtggaaga
     5881 tgctatcatc cgtcttgggc agaaggcgcg tgctgcaggt atccacatga ttcttgcaac
     5941 tcagcgtcca tctgttgatg tcatctctgg tttgattaag gccaatgttc catctcgtgt
     6001 agcatttgcg gtttcatcag gaacagactc ccgtacgatt ttggatgaaa atggagcaga
     6061 aaaacttctt ggtcgaggag acatgctctt taaaccgatt gatgaaaatc atccagttcg
     6121 tctccaaggc tcctttatct cggatgacga tgttgagcgc attgtgaact tcatcaagac
     6181 tcaggcagat gcagactacg atgagagttt tgatccaggt gaggtttctg aaaatgaagg
     6241 agaattttcg gatggagatg ctggtggtga tccgcttttt gaagaagcta agtctttggt
     6301 tatcgaaaca cagaaagcca gtgcgtctat gattcagcgt cgtttatcag ttggatttaa
     6361 ccgtgcgacc cgtctcatgg aagaactgga gatagcaggt gtcatcggtc cagctgaagg
     6421 taccaaacct cgaaaagtgt tacaacaata aaaaaatagc ttctttccaa gtttggaggg
     6481 aagctatttt agtggctatt gattgctttt attttctgaa gttggcgcat tggactgttt
     6541 ttcgttttca gtagcaggtt tacttgaagc aggagtagaa gagtcctgag ttgctgtttt
     6601 ctgatcttct tttttctctt ccttgacgct agattttggt gtttcctctt gctgtgtttt
     6661 ttcttgacta gtgttagtct ctttagttgg actggtgttt tccttagggg attccttttg
     6721 gatttctttg acaatggttg tcgtctggct tgtcgtaggt tcttttttaa tatttttgtt
     6781 attatccaag gcgttcataa tcgtgatact tgcggtaatc aagccaagga tactagcgat
     6841 tgtagcaacg gttttttgaa agactgtaaa gccttttttg atgtgttctg tttttggttt
     6901 tgaagttcta cgataattag acatacattc tctcctttaa ttaaaattta ttatacctca
     6961 tttctttaaa aaaatcttaa aaaaagagga gatttttcta cacgaacttc agtaattagt
     7021 tgaaataaaa tatgacttat gatataacaa aataaagaaa gcgatttcaa aaaaggaggg
     7081 cgttatatgt tcgaaattag aaatttgagt ctctcttttg caggcaggcg gttgctagag
     7141 ccaacagatt tgatatttga aaggggaaaa gtatatacaa tatatgggaa gtcaggcgta
     7201 ggaaagtctt ctttactgaa taaaattggt ttgctctctg ctacggatcc tagtgtttct
     7261 tatttcttcg atggaaaaga gattgatatc gaaaataaga aatcagtctc tgtctttata
     7321 gctgaagaag ttgcctttgt atttcagggg cgaaatctaa taaatgattt gaccgtattt
     7381 gaaaatttaa gactagcttt aaacttttat gacttgagtc cagatgaaat agaaagcaaa
     7441 attgatacag tattggcgga tttacagatt tcttctttaa agcatgctta tccagaagat
     7501 ttatccggtg gtgaagaaca acgagtggca atcgcaagag ccttagttac aggaaagact
     7561 ctcatcttag ctgatgaacc aacaagttct ttggataaag aaaatagaga aaaaatctcc
     7621 gccttgttaa ttgatttagc tcacaaatat cataaaattg tattgattgt ttcgcatgat
     7681 gaggcgatga ttgcaatagg agatgttcag cttcatttta aagaccataa attagttggg
     7741 aattgtctta ttttgaattc tgatgaaggg ataaaggatt ctaagaagtg gtcctcctgt
     7801 ttgtcgtctt ctcatacgaa gctatccgtt ttgaaacata gaaggccttt tttacctaga
     7861 ttattagcgt tttttatctc tcttgtagtt gctatagcag taacctctat taactttcag
     7921 tccttatttg cagataagta tcaccaactg gtgaacaact cactcgaaaa tggcttcttg
     7981 gtgattaatg attcgcttca tttacaaact acaaaagtgt tggatgattt tctcagtttt
     8041 gataaggagg aaatcacctc aattagcaca agtcagaata ttcaaaccgt caatccttat
     8101 atagagtttc tctctttggg tatgacgttt gataattcaa aagactattc acaacttcaa
     8161 aagaactttc agccaacttt gactattgat ggtcagacca gaagcttgac aagaaatttt
     8221 tcaattcaac ccttgtatca gacaaataca acacagaggc agatagagta ttttgatagg
     8281 agcaatgaaa aagggattta tctatctgag caattcattt cagatgaaaa attaccaaat
     8341 atagtttcgg gaactaccgt gacactgact ttttatattc caatttcttt atatgaatca
     8401 agtatagaga aagaggggaa tatattgaaa ggagatggcg gtttatttgt caaagtggat
     8461 aaaacatatc ctgttttagg gattgttaaa aaaagttatc cgtttgaata ttccccttat
     8521 gggaacaccc tatttatgaa tattgctgaa atggaagaat tgcaaaatga agcaattcaa
     8581 cagcatccca tgacgaagat ggctttagat ggttttcctt tgaaatcatg gatgccgagt
     8641 gcgattcatg tgttactaaa ggatagcggt gctattcctg aagaattgag tagaataaga
     8701 gcaatctctt cacaaattac tattttatca tcatatgaaa actacgaaga atttaataaa
     8761 ggactcacct atatcaggca atttttaatg ttgctatccc tagtcttact catccttgtc
     8821 atcgcagtat tgtcctttgt tttctttttg ctcaatcgtc ctcgacgctt tgaagtaggg
     8881 attttaaaat ctttgggata cagtactcaa aatattgttt ggcttttctt aaaagaatta
     8941 attggttatg gtaaaacaat ttcgatatta gcaagttgtt tactcgtcat tctttccatt
     9001 ttagcaatgc aagtgcttaa attggaaatt tcagatgttt ttaaattcta tctaacttcc
     9061 gttttcacct taattggatt atcagtctca gtactgataa taagtggctt actacctata
     9121 tacacaactt gtaggcaaac agttgtcgat actatccgaa agaatggatg aggtgatatc
     9181 atgaaacata agataatgaa aaaaataata gtggtagtgt ttgctatccc atggttaaca
     9241 tttttaagtc aagtacatgc agattatgta agtaagtcta gttctttaga cggttatagc
     9301 ttggtaggct tgaatgttct taatgtgact tttaatgctt ctggctattc tgatacttat
     9361 agtggcagtg tgtcaaatat gtatttcact gactgggctt ggtttcctaa tacgataagt
     9421 aatcgttcca cttggaaaag ttcgattcca tatggtcaac gcgcaaatgg tacagtccat
     9481 ataggtgtag gagtaaattc gccttgggga gcggttaatc tctggggcgg acaaaattac
     9541 ttttctttag atttttaaca gaaataatca aagttagata gaatgaataa gaatgctctt
     9601 gatgatggta tcaagagtat tttatgttat tcagattaat gcaaacattg ccctttcttg
     9661 tcgcaggctc cgtttcatga tacaatagaa ggagtgattt tagaaagcgt gagaaacatg
     9721 atttactttg ataattcggc gacgaccagt ccctatccag aagcccttga aacctatatg
     9781 caggtggctt caaaaatttt aggaaatcca tctagtctcc atcgtttggg agaccaggca
     9841 acacgaattt tagatgcttc ccgtcaacag attgcagatt taatcggtaa gaaaagtgat
     9901 gaaatcttct ttacatctgg tgggacagaa ggggataact ggatcatcaa gggagtagca
     9961 tttgaaaaag cccagtttgg caagcacatc atcgtatcag ccattgaaca tccagcagtt
    10021 aaggaatcag ccctctggtt gaaagctcaa ggttttgaag tggattttgc tccagttgat
    10081 aacaaaggat ttgtggatgt tgaggcgcta gaagatttga taagacctga tacgaccctc
    10141 gtttccatca tggcagttaa caatgaaatt ggctctgttc agcccattga ggctatttca
    10201 aaactattgg cagacaagcc aactatttcc ttccacgttg atgcggttca ggcgcttgcc
    10261 aagattccga ctgaaaagta tctgacagaa cgagtggatt tcgcgacttt ctctggtcac
    10321 aagttccacg gaatccgtgg tgttggtttt atctatatca agtctggcaa gaagattacg
    10381 cctcttttaa caggtggtgg tcaggaacgt gattaccgtt cgacaactga aaatgtggca
    10441 ggaattgcag cgaccgctaa ggctctccgt ttatctatgg aaaagctaga tatctttagg
    10501 agcaagactg ggcagatgaa ggcagtgatt cgtcaagcac ttctggacta tccggatata
    10561 tttgtctttt cagatgagga agacttcgcc cctcatattc tgacttttgg aatcaagggt
    10621 gttcgtggtg aggtcattgt tcacgccttt gaagactatg atattttcat ctcaacgacc
    10681 tcggcttgtt cgtccaaggc tgggaaacca gccggaaccc tgattgctat gggagtggac
    10741 aaggataagg ctcagtcagc tgtgcgtctt agtctagacc ttgaaaatga tatgagtcag
    10801 gtcgagcagt tcttgaccaa gctaaaatta atttacaatc aaactagaaa agtaagatag
    10861 gagcattcat gcagtattca gaaattatga ttcgctacgg tgagctgtca accaagggca
    10921 aaaatcgtat gcgtttcatc aataaacttc gcaataatat ttcagacgtt ttgtctatct
    10981 atccccaagt taaggtaaca gcagatcgcg accgtgccca cgcttacctc aatggagcag
    11041 attacacagc agtagcagaa tcgctcaaac aagtatttgg aattcaaaac ttttcccctg
    11101 tttataaggt tgaaaaatct gtagaagttc tgaagtctgc tgtccaagag attatgcagg
    11161 acatctataa ggaaggcatg acctttaaaa tctctagcaa gcgtagcgac cacacctttg
    11221 aattggacag tcgtgaactc aaccaaacgc ttggaggggc tgtattcgaa gccattccaa
    11281 acgtacaagc tcaaatgaaa agtcctgaca tcaatcttca ggtggagata cgtgaagaag
    11341 cagcctatct ttcttatgaa accgttcgag gggcaggtgg attaccagtg ggaacttctg
    11401 gtaagggcat gctcatgttg tcagggggaa tcgattcccc tgtagctggc tatctagcgc
    11461 ttaaacgagg ggtagatata gaggcagttc actttgccag cccaccttac acgagtcctg
    11521 gtgctcttaa aaaagcccaa gatttgaccc gtaaattaac caaatttggg ggaaatatcc
    11581 agtttatcga agttcctttt acagagattc aagaggaaat caaagccaaa gcgccagaag
    11641 cctaccttat gaccttgacg cgtcgtttta tgatgcgtat tactgaccgt attcgtgagg
    11701 tacgaaatgg tttagttatc atcaatgggg aaagtctagg tcaagtagcc agccaaaccc
    11761 ttgaaagtat gaaggctatc aatgctgtta ccaacactcc catcattcgt cctgtggtta
    11821 ccatggacaa gttggaaatc attgacatcg cccaggaaat cgataccttt gacatttcaa
    11881 tccaaccgtt tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa acaaatccta
    11941 aaattaagaa tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg gttgagcgag
    12001 cagtggctgg aatcatgatt actgaaatca cacctcaagc cgaaaaagat gaagttgatg
    12061 acttgattga caatctgctc taattcagaa aatccaaaag aatagcgaaa atcagtaaaa
    12121 aaagttagtt ttttctctaa aaacaggtga aaaactaact ttttttattt ttatgatata
    12181 atgatataaa attttgaata tagagagttt tctgacaatg aatcaatcct acttttatct
    12241 aaaaatgaaa gaacacaaac tcaaggttcc ttatacaggt aaggagcgcc gtgtacgtat
    12301 tcttcttcct aaagattatg agaaagatac agaccgttcc tatcctgttg tatactttca
    12361 tgacgggcaa aatgttttta atagcaaaga gtctttcatt ggacattcat ggaagattat
    12421 cccagctatc aaacgaaatc cggatatcag tcgcatgatt gtcgttgcta ttgacaatga
    12481 tggtatgggg cggatgaatg agtatgcggc ttggaagttc caagaatctc ctatcccagg
    12541 gcagcagttt ggtggtaagg gtgtggagta tgctgagttt gtcatggagg tggtcaagcc
    12601 ttttatcgat gagacctatc gtacaaaagc agactgccag catacggcta tgattggttc
    12661 ctcactagga ggcaatatta cccagtttat cggtttggaa taccaagaaa aaattggttg
    12721 cttgggcgtt ttttcatctg caaactggct ccaccaaccg ctatatcgag tgccagaaac
    12781 tatcgcctga ccaacgcatc ttcatctatg taggaacaga agaagcagat gatacagaca
    12841 agaccttgat ggatggcaat atcaaacaag cctatatcga ctcgtcgctt tgctattacc
    12901 atgatttgat agcaggggga gtacatctgg ataatcttgt gctaaaagtt cagtctggtg
    12961 ccatccatag tgaaatccct tggtcagaaa atctaccaga ttgtctgaga ttttttgcag
    13021 aaaaatggta agttaagaaa ggaaaaaacg aaatgcatat tgaacatctt agccactgga
    13081 gtggtcatcc taaccgtgaa atgtacctta accgttatgg acatggtggg attccagttg
    13141 tggtctttgc ttcatcaggt ggtagtcaca acgaatacta tgattttggc atgattgatg
    13201 cctgtgcttc ctttatcgag gaaggccgtg tccagttctt taccctatct agtgtggata
    13261 gtgagagctg gttggctact tggaaaaatg ctcatgacca agcggaaatg caccgtgcct
    13321 acgaacgtta tgtgattgag gaggccattc ttttatcaag cacaagacag gttagtttga
    13381 tggcatgatg acgacaggtt gctctatggg agcctatcat gcactcaatt tcttcctcca
    13441 gcatccagat gtctttacca aagtgattgc tctcagtggt gtttacgacg cacgtttctt
    13501 tgtcggtgat tactacaacg atgatgctat ttaccaaaac tcgccagtag attatatttg
    13561 gaaccaaaac gatggctggt ttattgaccg ttaccgtcag gcagagattg tgctgtgtac
    13621 ggggcttgga gcctgggaac aagatggttt accatccttt tacaagctca aagaagcctt
    13681 tgaccagaaa caaattccag cctggtttgc tgaatgggga catgatgtcg cccacgactg
    13741 ggaatggtgg cgtaaacaaa tgccttattt cctcggtaat ctctatttat aaaaggagtt
    13801 acctatgaat taccttgtta tttctcccta ctatccacaa aactttcaac agtttaccat
    13861 cgaactagct aataaaggca tcacagtctt gggaattggt caagagtctt acgagcaatt
    13921 ggatgagccc ttgcgcaata gcttgaccga gtattttcgt gttgataatc ttgagaacat
    13981 agatgaagtc aaacgtgcag ttgcttttct cttttataaa catggtccaa ttgaccgcat
    14041 cgagtctcac aatgaatact ggcttgagct agacgcaaca ctcagagaac aattcaatgt
    14101 ttttggtgcc aaaccagagg atctcaaaaa gacgaaatat aagtctgaaa tgaagaaact
    14161 tttcaaaaaa gcaggtgttc ctgtggtacc tggagctgtt atcaagacgg aagcagatgt
    14221 tgatcaagca gtgaaagaaa tcggtcttcc aatgattgcc aaacctgata atggagtggg
    14281 agcagccgca acctttaaac ttgagacaga agacgatatc aatcacttca agcaagaatg
    14341 ggaccattca accctttatt tctttgaaaa atttgtcact tccagcgaaa tctgtacctt
    14401 tgacgggctc gtggacaagg atggaaagat tgtcttctca acaacctttg actacgccta
    14461 tacaccgctt gacctcatga tttataagat ggacaattct tattatgtgc tcaaggatat
    14521 ggatcctaaa ctgcgcaagt atggggaagc aattgtcaaa gaatttggta tgaaagaacg
    14581 gtttttccat attgagttct tccgtgaggg ggacgattat attaccatcg agtacaataa
    14641 ccgccctgca ggtggtttta ccattgatgt ttataacttt gctcattcct tggaccttta
    14701 tcgtggctat gcagctattg tcgcaggaga ggagttcccg gcgtcagact ttgaaactca
    14761 gtattgtttg gctacttctc gccgtgcaaa tgctcactat gtttattcag aagaggattt
    14821 gcttgccaaa tatagccagc agttcaaggt taaaaaagtc atgccagctg ccttcgcgga
    14881 acttcaagga gattacctgt atatgctgac aactccgagt cgacaagaaa tggatcagat
    14941 gattgctgat ttcggacaac gtcaagaata agaactatcg gattaaggaa attcactccc
    15001 ttaatccttt tgttttgtct ggtaaaaaat aagagcatcc taacaaggta gctatcataa
    15061 aacttgttcg ataactattt gaagcaggat taggtggcta gaaattgaat tttaacattt
    15121 caatttagtc atagtattgt gttttcgtat ccttaaatca gctaaaagga tccatgacga
    15181 cacctatacg atatagtttt caggatacca aaccagtcta ttaatactca atgaaaatca
    15241 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgtggata
    15301 gaactgacag agtcagtatc atatacctac ggcaaggtga agctgacgta gtttgaagag
    15361 attttcgaag agtataaatc ttattgatga actgcttgca gtctgagaaa aaatgagctt
    15421 ggatattatt tccaaactca cttaaagtca atttcaatcc actagaacaa gcctagtaca
    15481 gttccatcgc tttcaacatc catgttgaga gctgctggac gttttggaag acctggcatg
    15541 gtcataacat caccagttaa ggcaacgatg aagcctgcac ctaattttgg taccaattca
    15601 cgaatggtaa tttcaaagtt ttctggtgct ccaagcgcat ttggattgtc tgagaaactg
    15661 tattgagttt tagccataca aattggcaat ttgccccaac cattttgaac gatttgagca
    15721 atttgtgttt gagctttctt ctcaaagttc actttgctac cacgatagat ttcagtgaca
    15781 attttttcaa tcttttcttg gacagaaagg tcattatcgt acaaacgttt atagttagct
    15841 ggattttcag caattgtctt aacaactgtt tcggcaagtg ctactccacc ttctgctcca
    15901 tcagcccaga cactagccaa ttcaactggt acatcgattg aggcacagag ttcttttaag
    15961 gctgcaattt cagcttctgt atcagataca aattcgttaa tagctacaac tgctggaata
    16021 ccgaacttac ggatattttc aacgtggcgt ttcaagttag caaaacctgc acgaactgca
    16081 tctacatttt cttcagtcag agcgtcttta gccacaccac cattcatctt aagggcacga
    16141 agggttgcga caataacaac tgcatctgga gatgttggca agtttggtgt cttgatatca
    16201 aggaatttct cagcaccaag gtccgcacca aaaccagctt cagtaacagt gtaatcagcc
    16261 aagtgaaggg ctgttgtcgt cgccaaaaca gagttacagc catgagcgat attggcaaat
    16321 ggaccaccgt gtacaaaggc aggtgtaccg taaattgtct gaaccaagtt tggcttaata
    16381 gcatccttca aaatcaaagc caaggcaccc tcaacctgca aatcacctac agaaacaggc
    16441 gtacggtcat agcgataacc aataacgata ttcgccaaac gacgtttcaa gtcctcgatg
    16501 tccgttgcca agcaaagaat tgccatgatt tctgaagcaa ctgtaatatc aaaaccatcc
    16561 tcacgtggaa taccgtttag aggaccacca agaccaacag tcacatggcg gagcgcacgg
    16621 tcgttcaagt ccacaacgcg tttccagagg atacgacgtt gatcaattcc cagctcattc
    16681 ccttggtgca agtggttgtc aatcaaggca gaaagggcat tgttggcagt tgtaatagca
    16741 tgcatatctc cagtaaagtg gaggttgatg tcttccattg gcagaacttg tgcataccca
    16801 ccaccagcag caccaccctt gatccccatg actggaccaa gagacggttc gcggatagca
    16861 atcatggttt tcttgccaat cttgttcaag gcatccgcaa gaccaatggt aagcgtcgac
    16921 tttccttcac ctgcaggtgt tgggttgatg gcagtaacca agatcaattt accaactgga
    16981 ttgctctcaa ctgcacgaat tttatcaaag ctgagtttag ccttgtactt tccgtacaac
    17041 tccaaatcgt cgtaagaaat accaagtttc tctacaacat caacaattgg cttcaactca
    17101 atactctgtg cgatttcaat atctgttttc attcaaaatt cctctaacct cttatatgat
    17161 aattcattat atcacaaaac aagattttta acatcctaaa actctctaaa cgttcgtaaa
    17221 tatctctgtt tttaaggctt ttagagtcct ttcttaaatt ttatatggct ttatagtttg
    17281 aaactatagt aaatcttcgt ttttaccaaa aatttatcac tttcatttta cttaccgctt
    17341 atttttgtgt acaatagtgc tatgaaaatt ttagttacat cgggcggtac cagtgaagct
    17401 atcgatagcg tccgctctat cactaaccat tctacaggtc acttggggaa aattatcaca
    17461 gagactttgc tttctgcagg gcatgaagtt tgtttaatta cgacaaaacg agctctgaag
    17521 ccagagcctc atcctaacct aagtattcga gaaattacca ataccaagga cattctaata
    17581 gaaatgcaag aacgtgttca ggattatcag gtcttgatcc actcaatggc tgtttctgac
    17641 tacactcctg tttatatgac agggcttgag gaagttcagg ctagctccaa tctaaaagaa
    17701 tttttaagca agcagaatca tcaggccaag atttcttcaa ctgatgaggt tcaggttttg
    17761 ttccttaaaa agacacccaa aatcatatcc ctagtcaagg aatggaatcc tactattcat
    17821 ctgattggtt tcaaactgct ggttgatgtt accgaagatc atctggttga cattgcacga
    17881 aaaagtctta tcaagaatca agcagattta atcatcgcga atgacctgac tcaaatttca
    17941 gcaggtcagc accgagctat atttgttgag aaaaatcagc ttcaaacagt ccagactaaa
    18001 gaagaaattg cagaactcct ccttgaaaaa attcaagcct atcattctta gaaaggaaaa
    18061 ctatggcaaa cattctcttg gctgtaacgg gttcaatcgc ctcttataag tcggcagatt
    18121 tagtcagttc tctaaaaaaa caaggccatc aagtcactgt cttaatgact caggctgcta
    18181 cagagtttat ccaacctttg acactacagg tactctcaca gaatcctgtc cacttggatg
    18241 tcatgaaaga accctatcct gatcaggtca atcatatcga acttggaaaa aaagcagatt
    18301 tatttatcgt ggtacctgca actgctaaca ctattgcaaa actagctcac ggatttgcgg
    18361 acaacatggt aaccagtaca gctctagccc taccaagtca tattcccaaa ctaatagctc
    18421 ctgctatgaa tacaaaaatg tatgaccatc cagtaactca gaataatctg aaaacattag
    18481 aaacctacgg ctatcagctg attgctccta aggaatccct actagcttgt ggagaccacg
    18541 gacgaggagc tttagctgac ctcacaatta ttttagaaag aataaaggaa actatcgatg
    18601 aaaaaacgct ctaatattgc acccattgct atcttttttg ctaccatgct cgtgatacac
    18661 tttctgagct cacttatctt taaccttttt ccatttccaa tcaaaccgac cattgttcat
    18721 attcctgtca ttattgccag cattatttat ggtccacgag ttgggattac acttggattt
    18781 ttgatgggat tacttagctt gacggttaac acgattacga ttctaccgac aagctacctc
    18841 ttctctccct tcgtaccaaa cggaaacatc tactcagcta tcattgccat cgtcccacgt
    18901 attttgattg gtttaactcc ttacttagtc tataaactga tgaaaaacaa gactggtctg
    18961 attttagctg gagcccttgg ttccttgaca aatactatct ttgtccttgg aggaatcttc
    19021 ttcctatttg gaaatgttta taatggaaat atccaacttc ttctggcaac cgttatctca
    19081 acaaattcaa ttgctgaatt ggtcatttct gcaattctaa ccctagccat tgttccacga
    19141 ctacaaacct tgaaaaaata aaaacaatct ccgctttcaa acctgaaggt ggagattttg
    19201 ctctatacag tttcttttta atgaaatctt tactatagta aaacgaaata agaacaggac
    19261 aaatcgatca ggacagtcaa atagatttct aacaatgttt tagaagtaga ggtggactat
    19321 tctagtttca atctactata acttttaact aaaaaatgat ctataaaccc aagtaaattc
    19381 ttgctttatt gtctggttta ttgtaccata ctagtgtata tgcagttaaa aaggagattc
    19441 ttgtgaatac acggaaaaag acacaattta tgacaatgac agccctttta acggctattg
    19501 cgattttgat tccaattgtt atgcctttca agattgtcat tccacctgct tcctatactt
    19561 tggggagcca catcgctatt tttatagcca tgttcttgtc gcccttgatg gcagtttttg
    19621 tcatcctagc ctctagtttt ggatttttga tggctggcta tcccatggtt atcgtttttc
    19681 gggctttttc ccatatatct tttggtgctt taggagctct ttacctacaa aaattccccg
    19741 ataccctaga taaaccaaaa tcttcctggg ttttcaattt tgttttggct gttgttcatg
    19801 cccttgctga agtattagcc tgtgtccttt tttacgcaac ttcgggtacc aatgtagaaa
    19861 acatgttcta tgttctattt gtactagttg gatttggcac aattatccat agtatggtag
    19921 actatacatt agcactagct gtctataaag tgcttcgaaa acgccgttaa aaggaaaagc
    19981 tatgacaaaa gatcgcaaac aagccctgct ccaactcttg aaagaagctc ctaaagccct
    20041 taatggccaa agtttggcgg aacattttca tgtcacacgt caggtcattg tgcaggacat
    20101 tgcaattttg agagccgatg gcgctcctat cctatccacc aatcgtggct acatctataa
    20161 gcaaattgat accaatcctt atgttcacaa acttttcaaa gtgaaacatg aagttgaaga
    20221 aatcggtcag gaactccttg ctattgtcga taatggtggg catgtccaga atactttgat
    20281 tgaccatccc gtttatggag aaattgaaac cttgcttaaa ctgtcttgcc gccgagacgt
    20341 tcaacatttt ctagaacaag tcgagcattc tgattttaaa cctttatctg aattgacaga
    20401 tggtgtccat taccacctag tcgaagccga aacacaacaa gacctccact atatcgagga
    20461 ggccttggat cagctaggtt atttagtaaa ggattagaaa attttctttt cccaatcgtc
    20521 ttctgtacgg cgagggtaga aaaattcaga tttgtccgat gcttccatca tctccatcaa
    20581 aggtagcata tcataggcca gatccaagtt tggaatctgg tctttttgca cccaagaaac
    20641 ttctccttca tctgaagagc gaagggtacc agagaactca gttgccttat aacaaacgac
    20701 aatatagcgc ccacctgtat ctagtggcca atttttaatg ccgacaagtt gaggattttg
    20761 gatagtcaac cctgtttctt catagatttc acgaatgaca gactctgcga aagattcgcc
    20821 attttctaca tggcctcctg gaaaggcata accagaccag cgattagttt caggagcgcg
    20881 atactgcatc accacgcgct gagcttcgag atcttcaatc agacaaatat ttgttaaaat
    20941 cgttaattgt gctcgagaca taaatttact cactttctaa tttattaaat ttttagactt
    21001 gataccagta ccattagctt ctacttttta aaattattta gaatagaata ccatccgttt
    21061 ttcctttatg ggctttccaa gttcaagtat cttttcttgt tcatcaaaag taaagcccat
    21121 tttttgatag aaagcaattg cgcgcttatt atctttcaat acccataaga aaatttcaga
    21181 aaaatgatta agagcaatca aagctgcttt tattaacttt tgtgcgatac cttttccata
    21241 atagtctttt aaaacatata aagcaataat ttcgccagct tgaatagtct catcacgaaa
    21301 gttgccataa ctgataaaac caactacctt cataccatcc atcgcaatca atgtattttc
    21361 tggatacttt tgactaaaga atcgacatct ttctaatgtc attgtctcct gaaattctgc
    21421 aggcaaaagg ccatcataag cctctctcca cgtttgccag tgaacaaggg gcttaccttc
    21481 tatctcttca ggagtttcca ttgatttgat aataaccgtc atttgttttc tcccagtctt
    21541 ctctcaaaat accatattta atactatcaa aatatttacc ttgataataa cgaacttttg
    21601 gaatatgagc ttcttttttc attcttaatt tttcagcaag tttcatcata ccaagattcc
    21661 ctgaccaagt tgtcaaaccc agatgctcca actccaagta atcctgaaac gtcctatcta
    21721 tccactgcaa catagcaact ttcccaatac cagtgttcca gaatttttta tcataaatac
    21781 caattcccaa ttccatccat cttgtttgtt tacataccca ataacgcgaa acagtcccaa
    21841 ctagtttatc atcaacaaaa ataccaaggc gatttgagtt gcttaaaatg gattctgatt
    21901 tttgtagttc gaattcttta aaatttgaaa aatactgata atcatcataa tagggagcat
    21961 catactgttt ccaaactgga ttaagttgtg aataagccat ttcccataaa gacatcaaat
    22021 cttctctctt taactttctt aaataaatca tactattccc ctaatccaag gccttgactt
    22081 ccaacatcat atcacggatc tgagccgcca gttcaaagtc aagtacttcg acggcttctt
    22141 gcatttgttt ttctagtttc ttgacgagtt ctttgcgctc ttgtttgttg aggctattga
    22201 tgtcgacttc cttgtcctct tccttagcaa ctgccttggt cacagcaatc aggtcacgga
    22261 tttctttctt gattgtctgt ggtacgatac catgctcttc attataggcc atctgaattt
    22321 tccgacggcg ggcagtttca tcgatagcac gttgcataga ctgggtaacc gtgtctgcat
    22381 acatgatgac atggccttca ctgttacgag cagcacgtcc aatagtctgg atgagtccac
    22441 gttcgttgcg aaggaaacct tccttgtcag catcgagaat agctacgagg ctcacttcag
    22501 gaacgtcaat tccttcacgg agcaggttaa ttccgaccaa gacatcaaag acacccaagc
    22561 gcaggtcacg gataatctcc gtccgttcca aggtcttgat atccgagtgc atgtacttaa
    22621 ccttgatacc catttccttg aagtagtcgg tcaagtcctc tgccattttc ttggtcaaag
    22681 ttgtgataaa ggtacgctca tttttttcaa cgcgggcatt gatttcaccc aagaggtcat
    22741 caatctgtcc catagtcgga cggacttcca cctctggatc caagagtccc gttggacgaa
    22801 tgatttgctc aatcactgtc tcggtctgtt cattttcata gtcaccaggt gtcgctgaaa
    22861 cgtaaacaat ctgatgaacg tgactctcaa actcctcccg acggagagga cgattgtcca
    22921 aagcagacgg caaacggaaa ccataattaa ccagcatttc tttacgcgaa cggtctccat
    22981 tgtacatgcc cttgatttgc cctatggtca tatgactctc gtcaatcata atcaagaaat
    23041 catctgggaa gaagtcgaga agcgtataag gaggctctcc ttcgctccgt ccatccatgt
    23101 ggcgagaata attttcaacc ccattggtat agcccatctc acgcaacatt tcgatatcat
    23161 actctgtccg ctgtttcaaa cgctgggctt caagcagttt accttccttt tcaaagacag
    23221 ctaattgttc ttccaactcg gcctgaatct ttgcaatggc aacttccatg tggtcgtcat
    23281 tggtcacaaa gtgtgtcgct gggaaaatcg ctaaatgatc cacttctccc aacacctgac
    23341 ctgtcagagc ctcaacttca cgaatacggt caatttcgtc tccaaaaaat tctactcgaa
    23401 aggcatgttc atctcgggaa gctgggaaaa tctctaccac atccccacga acgcgaaatc
    23461 ttccgcgttg gaaatcaata tcattgcgtt caaactgaat atcgaccaag tcattcaaga
    23521 gtttatcacg agaaatctct agaccaggac ggagactaac gacactatca gcgtattcct
    23581 tgggcgaacc caaaccatag atacaagaga ctgaggccac gacaataaca tcattacgct
    23641 ccaaaagggc tgaggtagct gagtggcgaa gcttgtcaat ctcgtcattg acagaactat
    23701 ccttctcaat ataggtatcg ctagaaggga cataggcctc tggctggtaa taatcatagt
    23761 aggatacgaa atactcaact gcattttcag ggaaaaattc cttaaactcc ccatagagct
    23821 gaccagccag agttttattg tgggcaataa ccagagttgg tttattgact ttagaaatga
    23881 cctgactcat agtataggtc ttccctgttc cagtcgcccc catcagaatc tgagcttttt
    23941 ctcccccctc aatgttatcc accaactgct cgatagcttg gggttgatct cctgatggtt
    24001 gatattttga tactagttta aattgattat ctgtaatgtg attgatcata agaatcctct
    24061 ctccatgtgc tattcctatt ttagcatact tatagtattt tcacgaagaa aaggacggac
    24121 cgaagtcaca tcctttcatt ttctttcttt aatttattag caagatagac aatcagcagt
    24181 agtaatacca gacttgtcat aatggaacct tctatgccaa aagaaccacc tgataaccaa
    24241 tcttgattgc cttgtggtaa aaaggtcatc agagacgttc ctgacggttg accactaact
    24301 aaaatcccaa agagattacc ctgagcaaaa ttccaagcac catgaatacc tgcaacaccc
    24361 caaactgtat cagttttgag aaggtaaaga gccatggcaa ctccgaataa aaagagattt
    24421 actagagata gaggggtgag gccagaattg cccatatgaa gcagggtaaa gaacaggcta
    24481 gatataagaa tagctagttt tagattggtt cttgaggcca attgaggaag tagccaagca
    24541 cgggccacca cttcttctgc tgtcccctgt aaaatccaaa atgggatagt aaagacgaca
    24601 aaggcaagag aataaggatt caagtgaatg gattccaaac gatattgacc taagaccacc
    24661 aaacctaaca aggtcagaag aaaaagtgcc agacctagac taaatccttt cagaagattg
    24721 ctgaggcaat tctctctata aaatcccaag gttcgaatag gtcttttctc aacttttctt
    24781 gtccatctga acacagtgtt aagaataaaa ccaaaggcca gtaatcctaa aattaaacga
    24841 aagtcacttg ttttatccgt caagctctga tgcaaggtct gcaagtaggt tgcaagattt
    24901 tgaccagcct ctccaaaatt tctagcaagt ccgatgagag ctaacaagcc aataccatac
    24961 aaagtaaaag ccacaaactc tcctatgaag acaaaaacaa aggctaacaa ggggcttgtg
    25021 taaatgttta aactcatttt tgaagcttgg aagtctttaa atattctttt gttcttcata
    25081 tccccgtcct ctttt
//
LOCUS       DAVMCN010000022        24032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVMCN010000022 DAVMCN010000000
VERSION     DAVMCN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.022"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(98..2356)
                     /locus_tag="VYP85_001113"
     CDS             complement(98..2356)
                     /locus_tag="VYP85_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1881642.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VYP85_001114"
     CDS             complement(2585..2815)
                     /locus_tag="VYP85_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1881643.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VYP85_001115"
     CDS             3005..3688
                     /locus_tag="VYP85_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1881644.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VYP85_001116"
     CDS             3688..4422
                     /locus_tag="VYP85_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1881645.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VYP85_001117"
     CDS             4576..5433
                     /locus_tag="VYP85_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1881646.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VYP85_001118"
     CDS             5575..6447
                     /locus_tag="VYP85_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1881647.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPESMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VYP85_001119"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VYP85_001119"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1881648.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VYP85_001120"
     CDS             7426..8637
                     /locus_tag="VYP85_001120"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1881649.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VYP85_001121"
     CDS             8639..9181
                     /locus_tag="VYP85_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1881650.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VYP85_001122"
     CDS             9197..10006
                     /locus_tag="VYP85_001122"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1881651.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..10877
                     /locus_tag="VYP85_001123"
     CDS             10482..10877
                     /locus_tag="VYP85_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1881652.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10887..11462
                     /locus_tag="VYP85_001124"
     CDS             10887..11462
                     /locus_tag="VYP85_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1881653.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11487..11999
                     /locus_tag="VYP85_001125"
     CDS             11487..11999
                     /locus_tag="VYP85_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1881654.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12653..13363
                     /gene="deoD"
                     /locus_tag="VYP85_001126"
     CDS             12653..13363
                     /gene="deoD"
                     /locus_tag="VYP85_001126"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1881655.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13386..13910)
                     /locus_tag="VYP85_001127"
     CDS             complement(13386..13910)
                     /locus_tag="VYP85_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1881656.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13963..14199)
                     /locus_tag="VYP85_001128"
     CDS             complement(13963..14199)
                     /locus_tag="VYP85_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1881657.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(14267..15187)
                     /locus_tag="VYP85_001129"
     CDS             complement(14267..15187)
                     /locus_tag="VYP85_001129"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1881658.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15377..15780
                     /locus_tag="VYP85_001130"
                     /pseudo
     CDS             15377..15780
                     /locus_tag="VYP85_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15996..16577
                     /locus_tag="VYP85_001131"
     CDS             15996..16577
                     /locus_tag="VYP85_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1881659.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16574..17851
                     /locus_tag="VYP85_001132"
     CDS             16574..17851
                     /locus_tag="VYP85_001132"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1881660.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17869..18531
                     /gene="deoC"
                     /locus_tag="VYP85_001133"
     CDS             17869..18531
                     /gene="deoC"
                     /locus_tag="VYP85_001133"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1881661.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18518..18907
                     /locus_tag="VYP85_001134"
     CDS             18518..18907
                     /locus_tag="VYP85_001134"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1881662.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            18997..20049
                     /locus_tag="VYP85_001135"
     CDS             18997..20049
                     /locus_tag="VYP85_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1881663.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20193..21728
                     /locus_tag="VYP85_001136"
     CDS             20193..21728
                     /locus_tag="VYP85_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881664.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SAGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            21721..22779
                     /locus_tag="VYP85_001137"
     CDS             21721..22779
                     /locus_tag="VYP85_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881665.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22782..23738
                     /locus_tag="VYP85_001138"
     CDS             22782..23738
                     /locus_tag="VYP85_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881666.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23823..>24032
                     /locus_tag="VYP85_001139"
     CDS             23823..>24032
                     /locus_tag="VYP85_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1881667.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMIHKV"
BASE COUNT         7007 a         4335 c         5462 g         7228 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttatca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggggcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatctgtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc aacaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaggaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac tattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa tcgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa aaggatgaaa
     5581 gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagtcta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagttg tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagag
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaattgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgca gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaatcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aattgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctgatat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt agtaagaata aggtcgtcat
     8701 ggcggagctt catcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttctttg cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcaga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatggggg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagattgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtgtgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggaggctacc
    10741 tagctcagat tgcagcggtt gaagattacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttgggatg
    10861 ctaagaatgg tttctgagat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aataatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagcgc gattctttaa gaaacaggct ctacctcaat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa caggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa acttccaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacgg ttctggtaaa gaaattgagt
    11461 gaaaacgtat aatatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaagataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgacagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 tagaactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaagaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaacaaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aaggaattga ccccacccta aaagtagtgg gaaaaagata
    12421 gttggtctag cgagcatcgc tcactgcgcc caactcctat tttcccttcg ctttttgatg
    12481 ggtttggtat ctttctcaat ataaaatata aaataaagaa aggtagagcg tgtgttttga
    12541 tttgaacacg agcggaaaac tcggaaaata gataatctga ctgaaaaatc aggatttctc
    12601 gtcaggttcc taattttcag tcgttttctt ctcgctcttt gtatcataaa ttatgtctat
    12661 ccatattgct gctcagcagg gtgaaattgc tgataaaatt cttcttcctg gggatcctct
    12721 tcgtgctaag tttattgcgg agaatttcct tggtgatgct gtttgtttta acgaagtgcg
    12781 taacatgttt ggttacactg gtacttacaa gggtcaccgt gtatctgtca tgggaactgg
    12841 gatgggaatg ccatctattt cgatttatgc gcgtgagtta atcgtagact acggtgtgaa
    12901 gaaattgatt cgtgtgggaa ctgcaggttc tttgaatgaa gaggttcatg ttcgtgaatt
    12961 agttttggcg caggcggctg caaccaactc aaacatcgtt cgtaatgact ggccacagta
    13021 cgattttcca caaattgcta gctttgattt gcttgataaa gcctaccata tcgccaaaga
    13081 acttggtatg actactcacg ttgggaacgt tttgtcatct gatgtctttt actcaaatta
    13141 ctttgaaaag aatatcgagc ttggtaaatg gggagtcaag gctgtggaaa tggaagcagc
    13201 agctctttac tatcttgctg cccaatacca tgttgatgcg ctagctatca tgaccatctc
    13261 tgatagcttg gtcaatccag acgaagacac aactgcagaa gaacgtcaaa ataccttcac
    13321 tgatatgatg aaggttggtt tggaaacctt gattgcagaa taattatagc caaaaaggaa
    13381 gccctttatg aattgtagga cttccttttc ttatccagaa attgatctag ctctctctga
    13441 tttcgaagaa tagtgacttt atgtgaatat tcttggcaaa gtttttggta attttctttt
    13501 tgagttttgc tacgcccatc ccaaagaatc catctgataa actcccagtc aaagcgttca
    13561 gggcaatctg ccgccatact ttctctgact tttccacggt atttaagata acgcttaaag
    13621 gctctaaaga gacaggtcaa tggcaaaaaa ttgagaaaga tgatttggtc agcttcttgc
    13681 attcgttctt ggtagtagca ccaagaataa ttaccatcga tgacccaagc tttatgcttg
    13741 gtgagaaagt tttttatctc ggttaacatc cattcgcagt cactgtcttg ccaaccaggt
    13801 tgaaattgga gtgtgtccat gtgcagtttt ggaatggagt agtagttaga taacttttct
    13861 gctagagttg acttaccaga accagaatat ccgataattg tgattttcat tttctacctt
    13921 ttcctatttg gagacaaaaa aacagcctct atggactgtt tcttatttag caagtttagt
    13981 tgaaagacga gctttatcgc ggcttgcttt gtttttgtga atcaaacctt tagtttctgc
    14041 tttatcgata gctgagctag cagcacggaa aagttcttca gatgggtttg cttcgaaagc
    14101 ttttatagca gtacgcatag ctgatttttg agctgagttc ttttcgtttt gtttaacgtt
    14161 caattcagcg cgtttgatag ctgatttaat gtttgccaat gttcttacct ccatatttac
    14221 taactatacc attatatatg aaaacttacg ttttgacaag ggaaaattac ttttttaagt
    14281 aaatttcatc gatttcatgg ttcttgcttt tatgaagaat cacttctgca cgatttctgg
    14341 ttggttcaat ataattttgc agatttgtga gattgatact gatccagacc tgatgggcaa
    14401 aggactccac ttccccaatc ggcatctgag taaaacgata atagtagcta tcagggtcgt
    14461 tttgggctag gctcagcatc ttcaagaaac ggtccagata ccaactttca atatcatcca
    14521 ctccagcatc tacatagatg gaaaagtcaa agaagtcagt gatatagaga cgatcgtttt
    14581 gtggattttg aaagacatta attccctcaa caattacaaa atcagcagct ttgacacttt
    14641 gtttcttttc gggtacgatg tcgtaaactt catgagaata gacaggaata tctacatctt
    14701 gtccattttt gatgcggtcc aagaagttga gaagagcttc catatcatag ctttcaggaa
    14761 atcctttacg atttaaaatc ccctgctcaa tcaaggtttg attgggatag agaaaaccat
    14821 cagttgtaac caactcaacc gtagcatctg taaacgtacg ggacagtagg atttgaagta
    14881 ggcgactggt tgtggatttt ccaacggcaa cactcccaga aaccccaata ataaaaggtt
    14941 gagatttact ttcacgttgg aggaaaattc cttttgaaaa ggctaaatct tccttagttc
    15001 gcttgtaaat ctgaatcaga tgagccaagg ggagatagat atctgtaacg tcttggagac
    15061 tgatttggtc attaaaactc ttgatagatt ccaattcttc ttctgtcaaa ggaggtgttg
    15121 tctttcgatg taaagattgc caagtctggc ggctgatttt ttcaaaatgt aaaaattcgt
    15181 tggtcatttg ttttccccta gatattttgt ttatcatacc ataaaaagct aaaaaaataa
    15241 agcggtttct tgaatgtggt aagtcaatgg tatatagtat aagtgatcaa tttattgatg
    15301 aaataggaga tagattctac tgatttataa gcttataaag ggggcttttt agttcacaac
    15361 ttataggagg tgtactatga aaatcttaaa acgttacata ttggaactct gttttatttt
    15421 aagttttgct ttacctttta taaaaggaac caatgcagat aatggtagat gctttgtgga
    15481 aacctattac ggttttactt ttttgatgga acatgctatt gtaacagctg tctttatttg
    15541 ttcgttctta attgctttct tactaaaaaa cgatggacga aatggattgc tgcgggtagt
    15601 tattgctttt tagtcctacg gattgcgaca gagggttatt tcttccacat gtcactagaa
    15661 gatttgatac gactttggac aagtttggaa atcctgacac aaacgtatca gttgggcttt
    15721 tatctaaaca ttttgttagg aattttgttg ataataaagt attttaaggt taagcaatag
    15781 aaataataat ctgcctgatt atagatgata aactttttgt ttttatctgg actgtgatat
    15841 ttatagttct aaatggttta ttatttataa gtgttgaaag agattgaaga aaatggcttc
    15901 gtgacttgct ttcttcggtc tttttcgttt tattatcaat ttgtaaacga tttacaattt
    15961 gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta ctatgcagaa aatcctgacg
    16021 ctgctcacga cattcatgag ttgagagtgg acttgttggg agaaaaaatg acttttttga
    16081 cagatgcggg tgtttttagc aagaaaatgg ttgactttgg aagtcaactc ttgctcaagt
    16141 gtctggatgt caaccaagga gagacagtcc tagatgtagg ctgtggttat ggtccattag
    16201 gtttgtcctt ggtcaaggtt tacggagttc aggcgaccat ggttgatatt aacactcgtg
    16261 ccctggattt agctcagaga aatgctgaaa aaaataatgc aaaagcgacg atatttcaat
    16321 ctaatattta tgcaagagtt caagggcgat ttgaccatgt catttccaat cctcctatcc
    16381 gtgcgggcaa gcaagtcgtt catgaaatca tcgagaaaag taaagatttc ttggaaattg
    16441 gtggagattt gaccatcgtc atccagaaaa aacaaggagc tccaagtgcc aaatctaaga
    16501 tggaagatgt gtttggcaat tgtgaaatcc ttaaaaaaga caagggatac tatatcctta
    16561 gaagtgtgaa agaatgagag cagttgattt aatccaaaaa aaacgagacg gtcaagaact
    16621 gacttcaagt gaaattgaat ggctgataga aggctatgta tcaggaactg ttcctgatta
    16681 tcagatgtct gcctttgcta tggctgttta ttttaaagga atgacgactc gagaaatctc
    16741 tgatttaacg atgaatatgg ttaagactgg gcaagagttt gacctgtcag ccattgatgg
    16801 tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat aaggtaacct tgattttagc
    16861 tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg agtggtcgtg gtcttggcca
    16921 tacaggcgga acaattgata aattggagtc cattaggggc tatcaagtag aacgtagtca
    16981 agaggatttt attcgtcagg ttcaggatat tggagtatct gtcattgggc aatcagacca
    17041 gctggtcaaa gcagataagc ttctctatgc ccttcgtgat gtgaccgcaa ctgtcgacac
    17101 gattcctttg attgcgagtt cggtgatgag caagaaaatt gcggcagggg cggatgctat
    17161 tttgctagac gtgactgtcg gtgagggtgc cttcatgaag acggttgatg aggcgcgtga
    17221 gttggctcaa actatggtag atcttggtaa ggttgttgga cggaagacag tagcagtgat
    17281 tacggatatg agccagcctt tgggacgagc gattggaaat cgtctggaaa tccttgaagc
    17341 attggagatt ttgcaaggtc aaggacgtca ggatattacc cactttattt gtgaattggc
    17401 tcaaattatg cttggtttgg caaatgttaa caaaactgtt gaagaagttc gccaacatct
    17461 tgaaaatggt caagcactgg ctaagtttga ggaaatggtg caagcccaag gtggagactt
    17521 ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg gaaatccctg ctcaggaaac
    17581 gggtgtcatt tcagctcttc cagctatgga ctttggtctt tatgccatga ggctgggtgc
    17641 tggtcgtgca gttaagtctg atgtcttgga ctatgaaaca ggaattgttt ttgaaaagaa
    17701 gattggagac tccgttcaaa agggtgaaat tgttgcaaaa gtatacacaa atgaaaaaat
    17761 tccacctcaa ctagttacag atttccaaaa atgtgttaaa ataagtgatg aagtgaaaaa
    17821 aatccgtgaa attgtagaaa tcatctccta aatggaggga aaaccgaaat gaaattaaat
    17881 aaatatatag atcatacgct tttaaaacaa gatgcaaaga aaaaacaaat tgatagtttg
    17941 ttgtctgagg ctagagagta tggctttgcc agtgtttgcg ttaatccgac ctgggttgaa
    18001 catgctaaaa aaggacttga aggcacagat gttaaggttt gcacagtagt aggtttcccc
    18061 ttgggagcaa caacttcaac tgtgaaagct tttgaaacaa aagaagctat ccaaaatggg
    18121 gctgatgaga ttgacatggt gatcaatgtt ggagctctca aatcaggtaa tttagccttg
    18181 gttgagtcag atattcgcgc agtagtggaa gcaagtggtg ataagttagt gaaagtcatt
    18241 attgaagctt gccttctgac agaccaagaa aaaattgttg tttgccaatt ggcccaaaaa
    18301 gctggggctg actttgttaa aacatctact ggcttttcaa ctggtggtgc tacgatagca
    18361 gatgttagat taatgcgtga aacagttgga tctgatatgg gagtcaaggc tgctggtgga
    18421 gctcgttctt atgcagatgc tcttgccttt gtcgaagcag gtgcgacccg tatcggaacg
    18481 tcagctgggg tagctatttt aaaaggagaa ttggcagatg gcgactactg agttgattga
    18541 actggcaatt gaaaccagca aacatgccta tgtcccctat tctcactttc ctatcggagc
    18601 agttttagta gccaaagacg gaagtgttta cacgggagtg aatatcgaaa atgctagcta
    18661 tcctttgacc aattgcggtg agagaacagc tgtttttaag gctatatctg aaggccaaag
    18721 agaattttca gaattgattg tctatggtca aactgaaaaa ccgatctcgc catgtggtgc
    18781 ttgtcgccaa gtaatggtcg aattttttga acaagattta aaagtgacct tagtcgcaaa
    18841 agataaatcg acggtcgaga tgacggtcgg ggaattactt ccatactctt ttacagactt
    18901 aaactagtct gagtcgctct ctgagtggca cggtccttgt ggccaaccaa tccatacttg
    18961 caacatcgtt gcacatctta tttaggaggt tcagtaatga acaagaaaca atggctaggc
    19021 cttggtctag ttgcagtggc agcagttgga cttgctgcat gtggtaaccg ctcttctcgt
    19081 aacgcagctt catcttctga tgtgaagaca aaagcagcaa tcgtcactga tactggtggt
    19141 gttgatgaca aatcattcaa ccaatcagct tgggaaggtt tgcaggcttg gggtaaagaa
    19201 cacaatcttt caaaagataa cggtttcact tacttccaat caacaagtga agctgactac
    19261 gctaacaact tgcaacaagc ggctggaagt tacaacctaa tctttggtgt tggttttgcc
    19321 cttcataatg cagttgaaga agcagctaaa gaacacactg acttgaacta tgtcttgatt
    19381 gatgatgtga ttaaagacca aaaaaatgtt gctagcgtaa ctttcgctga taatgagtca
    19441 ggttaccttg caggtgtggc tgcagcaaaa acaactaaga caaaacaagt tggttttgta
    19501 ggtggtatcg aatctgaagt tatctctcgt tttgaggcag gattcaaggc tggtgttgcg
    19561 tcagtagacc catctatcaa agtccaagtt gactacgctg gttcatttgg tgatgcggct
    19621 aaaggtaaaa caattgcagc cgcacaatac gcagccggtg cagatattgt ttaccaagta
    19681 gctggtggta caggtgcagg tgtctttgca gaggcaaaat ctctcaacga aagccgtcct
    19741 gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc aagaagcaga aggtaaatac
    19801 acttctaaag atggcaaaga atcaaacttt gttcttgtat ctactttgaa acaagttggt
    19861 acaactgtaa aagatatttc taacaaggca gaaaaaggag aattccctgg cggtcaagtg
    19921 atcgtttact cattgaagga taaaggggtt gacttggcag taacaaacct ttcagaagaa
    19981 ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg atggaagcgt aaaagttcct
    20041 gaaaaataat ggatggaagt catttcttag gaagcggcca agggccgctt ttttaagagt
    20101 tgagacaaag tcattttgtc tcagtaaagc ttgctactag acaaactagc aagttttatt
    20161 gaaataaaat aagactctga aaggaagagc acatggcaca cgaaaatgtc attgagatgc
    20221 gtgatattac caaggtgttt ggtggatttg ttgccaacga caaaatcaac ttgcacctac
    20281 gaaaaggtga aattcatgca cttttaggag aaaatggggc tggtaagtcc acgctaatga
    20341 acatgttagc aggccttctt gaaccaacta gtggtgaaat cgcggtcaac ggtcaagttg
    20401 tcaatctcga ctccccatct aaagcagcta gcttgggaat cgggatggtt caccagcact
    20461 ttatgttggt tgaagccttc acagtggctg aaaacatcat tttaggtagt gaattgacta
    20521 aaaatggtgt gctagatatc gctggagcta gcaaagaaat caaggctctt tctgaacgtt
    20581 atggcttagc tgttgaccct tctgccaagg tagcagatat ctcagttgga gcccaacaac
    20641 gtgtagaaat tttaaaaaca ctttatcggg gggctgatat ccttatcttt gacgaaccaa
    20701 cggctgtttt gactccatca gaaattgatg agttgatggc tattatgaaa aatcttgtca
    20761 aagaaggaaa atcaattatc ttgattaccc acaaattgga tgaaattcgc gcagtttctg
    20821 accgtgttac agttatccgt cgtgggaaat caattgaaac cgttgaaatt gcaggggcta
    20881 ccaatgctga tttggcggaa atgatggtag gacgttctgt ttcctttaaa acagagaagc
    20941 aagcctctaa accaaaagaa gtggttttgt ctatcaaaga tttggtggtc aatgaaaacc
    21001 gtggtgttcc agctgttaaa aatctgtcct tggatgttcg tgctggagag attgttggta
    21061 ttgcggggat tgatggaaat ggtcagtctg aactgattca agccattaca ggtcttcgta
    21121 aggttgaatc tggtagcatt gagctaaaag gagattcaat tgtaggcttg cacccacgtc
    21181 agattacaga actaagtgct gggcacgttc cagaagaccg tcaccgtgat ggcttgattt
    21241 tggaaatgat gatatctgaa aatattgccc ttcaaaccta ctataaagaa ccacatagta
    21301 aaaatggaat tttgaattat tcaaatatta cttcttatgc taaaaagctg atggaagagt
    21361 ttgatgttcg cgctgccagt gaattagttc ctgcagctgc actctcagga ggaaatcaac
    21421 aaaaagcaat tattgctcgt gaaattgatc gagatcctga tctccttatc gttagccagc
    21481 caactcgtgg gttggatgtc ggtgccattg agtatatcca caaacgcttg attgaagagc
    21541 gtgataatgg caaggctgtc cttgttgtca gctttgaatt ggatgagatt ttaaacgtct
    21601 cagaccgtat tgccgttatc cacgatggta agattcaagg tattgtatca ccagaaacaa
    21661 ccaataaaca aggacttggt gtcttgatgg ctggtggaaa cttgggaaag gagaagagtg
    21721 atgtctaaaa aattacaaca aatttcggtt cccttgattt ctgtattcct aggaatttta
    21781 ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta tttggggcta cgaagaattg
    21841 ttctatacag cctttggcag tctgcgtggg attggagaaa tcttccgtgc tatgggtcct
    21901 ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag ctggtttctt taacgtcgga
    21961 cttcctggtc aggctttggc aggttggatt ctcagtggtt ggtttgccct gtcgcatcca
    22021 gatatgcccc gtcccttgat gattctagca accatcgtga ttgccttgat tgctggtggg
    22081 attgtcggag cgattccagg tattcttagg gcctatctag ggacgtcaga ggttattgta
    22141 accatcatga tgaactacat tgtcttgtat gtagggaatg cctttatcca tgctttccct
    22201 aaagacttca tgcaaagtac agattcgacc attcgtgttg gggctaatgc aacctatcag
    22261 acaccttggt tagctgagtt gactggtaac tcacggatga atattggtat tttctttgcc
    22321 atcattgccg ttgcagttat ttggttcatg ctcaagaaaa caactcttgg ttttgaaatc
    22381 cgtgcagttg gtcttaatcc acatgcttca gaatatgctg gtatttctgc caagcggact
    22441 attatcctat ctatgattat ttcaggtgcc ttggcaggtc ttggtggagc tgttgaaggt
    22501 ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat tagctatcgg atttaacgga
    22561 atggcggtta gtttgcttgc ggccaactca ccaattggta tactctttgc agccttccta
    22621 tttggcgttc tccaagttgg ggctcctggt atgaatgcgg cgcaggtacc atctgagctt
    22681 gtcagcattg taacagcgtc tattatcttc tttgtcagtg ttcattacct tatcgaacgc
    22741 tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa gatgtctatt ataaccttgc
    22801 tccccctctt ggtgtcttct atgctgattt actcagcacc tctcatcttt acaagtatcg
    22861 gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg ccttgaagga attatggtta
    22921 tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc agaacaattt ggagcagcaa
    22981 ctccatggct atccttgctt gtagcaggat tggttggtag tgttttctct atcatccacg
    23041 cagcagcgac ggttcatttc cgtgcagacc atgttgtcag cggtacggta ttgaacttga
    23101 tggcgcctgc cttggctgtt ttcttagtta aagttcttta taacaaagga caaaccgaca
    23161 acctaagtca aacttttgga cgctttgatt tcccagtctt ggcaaatatc ccagtgattg
    23221 gtgatatctt cttcaagtca actagtctac ttggttatct ggcgattgcc ttctcattcc
    23281 ttgcttggtt tattctcttt aagactcaat ttggtcttcg tctccgctct gtcggtgaac
    23341 atcctcaagc agcggatacc ttgggaatca acgtctacaa gatgagatat ttaggggtta
    23401 ttatttcagg ttttctaggt ggaattggcg gagcgattta tgcgcaatca atctcagtta
    23461 acttctcagt gacaactatt gttggacctg gatttatcgc ccttgctgcg atgatctttg
    23521 ggaaatggaa tccaatcggt gctatgcttt ctagtctctt ctttggactt tcacaaagtt
    23581 tggctgttat cggttctcaa ttgccgttcc tacaaggagt gccagcggtt tatcttcaaa
    23641 ttgcacctta tgttttgaca attcttgtct tagcagcctt ctttggaaaa gcagtcgcac
    23701 caaaagcaga tggtatcaac tacatcaaat caaaataagc atacaaaaaa acgtcagtcc
    23761 aatgactgaa ctgcccccca aaagttagac agaaaaaatc taacttttgg ggtgttttta
    23821 ttatgaaatt aacttatgat gataaagttc agatctatga acttagaaaa caaggatata
    23881 gcttagagaa gctttcaaat aaatttggga taaataattc taatcttaga tatatgatta
    23941 aattgattga tcgttacgga atagagttcg tcaaaaaagg aaaaaatcgt tactattctc
    24001 ctgatttaaa acaagaaatg attcataaag tc
//
LOCUS       DAVMCN010000023        22897 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVMCN010000023 DAVMCN010000000
VERSION     DAVMCN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.023"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            396..1871
                     /locus_tag="VYP85_001140"
     CDS             396..1871
                     /locus_tag="VYP85_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1881668.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINTIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(2174..3114)
                     /locus_tag="VYP85_001141"
                     /pseudo
     CDS             complement(2174..3114)
                     /locus_tag="VYP85_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3370..4230
                     /gene="speE"
                     /locus_tag="VYP85_001142"
     CDS             3370..4230
                     /gene="speE"
                     /locus_tag="VYP85_001142"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1881669.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            4227..5486
                     /locus_tag="VYP85_001143"
     CDS             4227..5486
                     /locus_tag="VYP85_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1881670.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            5486..6613
                     /gene="nspC"
                     /locus_tag="VYP85_001144"
     CDS             5486..6613
                     /gene="nspC"
                     /locus_tag="VYP85_001144"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1881671.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6610..7695
                     /gene="aguA"
                     /locus_tag="VYP85_001145"
     CDS             6610..7695
                     /gene="aguA"
                     /locus_tag="VYP85_001145"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1881672.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7705..8580
                     /gene="aguB"
                     /locus_tag="VYP85_001146"
     CDS             7705..8580
                     /gene="aguB"
                     /locus_tag="VYP85_001146"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1881673.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8761..9570)
                     /locus_tag="VYP85_001147"
     CDS             complement(8761..9570)
                     /locus_tag="VYP85_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1881674.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9842..10063
                     /locus_tag="VYP85_001148"
     CDS             9842..10063
                     /locus_tag="VYP85_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1881675.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            10117..10788
                     /locus_tag="VYP85_001149"
     CDS             10117..10788
                     /locus_tag="VYP85_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1881676.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10840..11037)
                     /locus_tag="VYP85_001150"
     CDS             complement(10840..11037)
                     /locus_tag="VYP85_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881677.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            11030..11938
                     /locus_tag="VYP85_001151"
     CDS             11030..11938
                     /locus_tag="VYP85_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1881678.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11935..12396
                     /locus_tag="VYP85_001152"
     CDS             11935..12396
                     /locus_tag="VYP85_001152"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1881679.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            12386..13273
                     /locus_tag="VYP85_001153"
     CDS             12386..13273
                     /locus_tag="VYP85_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1881680.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            13276..15148
                     /gene="cbpE"
                     /locus_tag="VYP85_001154"
                     /gene_synonym="pce"
                     /pseudo
     CDS             13276..15148
                     /gene="cbpE"
                     /locus_tag="VYP85_001154"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
     gene            15228..16358
                     /locus_tag="VYP85_001155"
     CDS             15228..16358
                     /locus_tag="VYP85_001155"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1881681.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            16368..17630
                     /locus_tag="VYP85_001156"
     CDS             16368..17630
                     /locus_tag="VYP85_001156"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1881682.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVAFPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17634..18431
                     /gene="proC"
                     /locus_tag="VYP85_001157"
     CDS             17634..18431
                     /gene="proC"
                     /locus_tag="VYP85_001157"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1881683.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     SSLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18651..19289
                     /locus_tag="VYP85_001158"
     CDS             18651..19289
                     /locus_tag="VYP85_001158"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1881684.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            19286..20176
                     /locus_tag="VYP85_001159"
     CDS             19286..20176
                     /locus_tag="VYP85_001159"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1881685.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFESLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            20216..20533
                     /gene="yabA"
                     /locus_tag="VYP85_001160"
     CDS             20216..20533
                     /gene="yabA"
                     /locus_tag="VYP85_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1881686.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20536..21405
                     /gene="rsmI"
                     /locus_tag="VYP85_001161"
     CDS             20536..21405
                     /gene="rsmI"
                     /locus_tag="VYP85_001161"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1881687.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            21632..22150
                     /locus_tag="VYP85_001162"
     CDS             21632..22150
                     /locus_tag="VYP85_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1881688.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            22259..22396
                     /locus_tag="VYP85_001163"
     CDS             22259..22396
                     /locus_tag="VYP85_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1881689.1"
                     /translation="MDFEYFYNREAKRFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     K"
     gene            22403..>22897
                     /locus_tag="VYP85_001164"
     CDS             22403..>22897
                     /locus_tag="VYP85_001164"
                     /inference="COORDINATES: protein motif:HMM:NF018653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1881690.1"
                     /translation="MSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVK
                     KGIGLIERVRLGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQ
                     EVKNLDSNYIENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIR
                     LPAKL"
BASE COUNT         6864 a         4101 c         5282 g         6650 t
ORIGIN      
        1 taaagcttag aaaatgagat gatgttttct agcaaatata aacccgagta aaaaatgcct
       61 acggacaggc agggttgaat gccgaagcgt ggttgaaaag ccacattatt gatagggtta
      121 aaagcctact tttataagtt gatgttagga cacttgttct aattcataaa tttttagtgt
      181 ggtgaaagca cacgtcatct tgtgaaacga tcaataaagt acgtaatatt tgctactaga
      241 gagttaggaa acatcgggaa cagacatact caacagaaac caaaataaac acgtcagaag
      301 attgcagagc aggtgaaaac ctgctctttt ttcatgagtc aacctttagt tccttagttt
      361 tcataaggtc ctaaaaatat tgaaaggagt atgttttgaa agagttagat caaaaccaag
      421 ccccaattta tgaggccttg gtgaagttac gcaagaaaag gattgttccc tttgatgttc
      481 caggtcacaa gcgtggacgg ggaaatccag aacttgtcga actcttagga gaaaaatgtg
      541 taggcattga tgtcaattcg atgaaaccct tggataattt aggccatcct atttcgatta
      601 ttcgtgatgc agaggagctg gctgcagatg cttttggagc tagccatgcc tttctaatga
      661 ttggtggaac aacttcatcg gtgcagacta tgattctggc aacctgcaag gcaggagata
      721 agattattct gccacgaaat gtccataaat ctgctatcaa tgcgttggtt ctatgtggtg
      781 ccattcccat ctatatcgag atgagtgtag atcctaagat tggtatcgct ttaggtcttg
      841 aaaatgaccg agtagcacag gccataaagg accatccaga tgctaaggct atcctaatca
      901 acaatcctac ttactacggc atctgttcag acctaaaggg gttgacagaa atggctcatg
      961 aagctggcat gatggtttta gtagatgaag cccatggagc gcatttgcat ttcactggta
     1021 aacttccaat ttctgctatg gatgcaggag ctgatatggc agcagtttcc atgcataagt
     1081 ctggtgggag tttgacacaa agttcgcttc ttttaatcgg ggagcagatg aatcccgagt
     1141 acgttcgtca gattataaac ctgacccagt ctacatctgc ctcttactta ttgatggcta
     1201 gtttggatat ttcacgtcgc aacttggccc ttcgtggtaa agagtcgttt gaggaagtca
     1261 ttgagctatc cgagtacgct cgtcatgaaa tcaataccat tggcggttac tatgcttact
     1321 caaaagagtt aatagatggt gtgtcggtct gtgattttga tgtaaccaag ttgtcagttt
     1381 acactcaggg aataggctta acaggtatcg aggtttatga cctcttgcga gacgaatacg
     1441 acattcagat cgagtttggt gatatcggca atatcttggc ctatatttcc atcggcgacc
     1501 gcatccaaga catcgagcgc ttggttggtg ctctggctga tattaagaga ctctattcaa
     1561 gagatggaaa agatttgata gcaggagaat atattcagcc cgagttagtg ctgtctccgc
     1621 aagaagcctt ctattcagag agaaaaagtt tgaccttgga cgaatctgtt ggacaggtct
     1681 gtggggaatt tgtcatgtgt taccctccag gaatccctat cttggctcct ggcgaacgca
     1741 tcacacgaga aattgtcgac tatatccaat ttgccaagga acgtggttgc tccctccaag
     1801 ggacggaaga tccagaggtc aatcacatca acgtcattaa gagaaagaca aactataaga
     1861 aaagtcaata gttttatcta aactatttct tatttcaatt tgatgatttg gcgatgattt
     1921 tagagcatgg caaaaagctc ttgaaaaagt ccattttttc aaaggtaatc ctgtgttaat
     1981 ttcagaaatt acatcacttt ttgttcgtca aatggcagct cttttttagg atataaaaca
     2041 gggttcggat aagttttttt gcaaggtgga tgatggctac attgtaatgt tttccttatt
     2101 ctaacttagt cttaagatag gccttaaaag caggtgaaaa gcgagggcat gctttggcag
     2161 cttgtatgag tgcctaccgc agatgagggg aaccccgttt gatcattctt ccagctaaat
     2221 caatctgacc tgactgataa atagaagaat ccagtccagc gaaagcttgt aattgagcag
     2281 gattatcaaa ggcatgaata tttcgaatct cggctaaaat gaccgcccct aaacgattct
     2341 caattccagt gaccgtcgtg atgaccgagt tgaactcagc catcaagtca ttgacacatg
     2401 tttccgcctt gtcaatgagc ctcttgtaat gtttgatgat ttcgaattca cgagcaggag
     2461 atgttgttcc gatagaacga ggtgcgactg agaggatatc ctgaatttta gaagcggtca
     2521 atcgcttaat ttctatcagc ttatcaaatc ctgcctcaat ccttttctga ggattagggt
     2581 agcgtgtcaa gagttggtag gtatattctg aatgctttcc aacgatttta tccaactcag
     2641 gaaagatgat atcaagacaa cgagtgtatt gtactttcca atcagactgt tttttcttga
     2701 gacgatgaat atgtctagtc agtattttta gttctacttg ccgattatcg tgttgaaatt
     2761 gttcacgatt ggggtcagaa agaagtttaa gagcgatgcc atgagcgtct ttcttatccg
     2821 ttttagtctt gcgaagtgat aatgatttgg caaattcctt gatgagcaaa ggagtgtagg
     2881 tgtaaacttt atatccttgt tcatgcagga agttcagtag attaaaggca taatgtccgg
     2941 tattttcaag agcgatgaga cagtcttggt tgagttgtcg aagagacaga tctaagagtt
     3001 caaaaccagc tttattattt gaaaaagtga gtggtttaag aacagttttc ctcgaacatt
     3061 caaggctgta acatcgtgtt tatttttagc gacatcaatg cccacataaa gcatgggagt
     3121 acctccagat atagtatttc aagtctactt ggttatccac gaactttttg ccttgttacc
     3181 ttagacgaga taaaacgtct atgcgttatc aaactcatta ccaattgaaa caaaaagctg
     3241 tggttagacc ctttcggaaa tcgtcaagcg attggaggaa atgaactaat ccacagtggc
     3301 ttattccaag tataccactt gggctttggc agtagctaac tgcgctaaat ataatataag
     3361 gagaaataga tggatttatg gttttctgaa gttcatactc cagatgtcaa attgtctctg
     3421 agaacagcca agcaacttta cgctggaaaa agtgaatggc aggatatcga agtcttggat
     3481 acgccagctt ttgggaaaat actgatttta aatggccatg tcttgttctc agatgcggat
     3541 gatttcgtct acaatgaaat gaccgttcac gttcccatgg ctgtccaccc aaatccaaag
     3601 aaagtattgg ttattggggg tggtgacggc ggtgttgccc aagtattaac actctatcct
     3661 gaactggaac aaatcgatat cgtggaaccg gatgagatgt tggtcgaggt ctgtcgtgag
     3721 tatttcccag actttgctgc aggcctagat gatcctcgtg ttaccattta ctaccaaaat
     3781 gggctacgct ttttgcgaaa ctgcgaatat gactatgata ttatcatcaa cgatgcgaca
     3841 gatccatttg gccatacgga aggactcttt accaaggaat tctacggcaa tagttatcga
     3901 gctctgaagg aagacggcat catgatttac cagcatggga gtccgttctt tgacgaggat
     3961 gagtcggcct gccgaagcat gcaccgcaag gtcaatcaag cctttccaat cagtcgggtt
     4021 tatcaggccc atattccaac tagcccagct ggctattggt tgtttggatt tgcatcgaaa
     4081 aaataccacc ctgtcaaaga ttttgacaag gaaggctgga aaaaacgcca gcttttcaca
     4141 gaatactaca ctgcaaactt acacgtggga gcctttatgt tgcccaagta tgttgaggac
     4201 attttagaag aagaggaagg aaaaaaatga gtcgtttact agttattggt tgtgggggcg
     4261 ttgcccaagt tgctatttca aagatttgtc aagatagcga aacatttaca gagattatga
     4321 ttgctagccg taccaagtca aaatgcgatg acttgaaagc taaactggaa ggcaaaacaa
     4381 gtacaaagat tgagacagct gctcttgatg ctgacaaggt tgaagaagtg attgctctga
     4441 ttgaaagcta caaaccagaa gctgttttga atgtagctct gccttatcaa gatttaacca
     4501 ttatggatgc ttgtttggca acaggtgttc actatatcga tacagccaac tacgaagcag
     4561 aagacacaga agaccctgag tggcgtgcta tctacgaaaa acgttgtaag gaacttggtt
     4621 ttacagccta ctttgactac tcatggcagt gggcttatca agagaaattc aaagaagcag
     4681 gcttgactgc tcttcttggt tctggttttg acccaggtgt aactagtgtc ttttcagctt
     4741 atgccctcaa acactatttt gatgaaatcc attatatcga cattttagac tgtaatggcg
     4801 gtgaccacgg ttatccattt gcaaccaact ttaatccaga aattaatctc cgtgaggttt
     4861 ctgcgccagg ttcttactgg gaagatggga aatgggtcga agtcgaagct atgtctatca
     4921 agcgtgagta tgatttccct caagttggac aaaaagatat gtatctcctt caccatgaag
     4981 aaatcgaatc attggccaag aacattccag gtgtcaaacg cattcgtttc tttatgactt
     5041 ttggtcaatc ttacttgacg cacatgaaat gtcttgaaaa tgttggactc cttcgtacgg
     5101 ataccattaa ctttaacggc caagaaattg ttccaattca atttttgaaa gccttgcttc
     5161 cagatcctgc tagccttggt ccacgtactg taggtaaaac caatattgga tgtatcttta
     5221 caggtgtcaa agacggtgtc aaaaagacta tctatatcta caatgtctgc gaccatcagg
     5281 aatgttacgc agaggttggt tcgcaagcta tttcttatac gacaggagtt ccagccatga
     5341 ttgggacaaa attagtcatg aacggaactt ggaaacaagc tggagtgtat aaccttgagg
     5401 agttagatcc agatccattc atggaagctt tgaatgagta tggtttgcca tgggttgtgg
     5461 ttgaaaatcc acaaatggtg gactaatgaa gttagaacaa gtaccaacac cagcctatgt
     5521 tattgacttg gccaagttag aagctaattg ccgcattcta caatatgtac aagaagaggc
     5581 cggttgcaag gtcttgcttg cccagaaggc atattccctc tacaaaactt atcccttgat
     5641 tagccagtat ctatcaggta cgacagctag tggactctat gaggccaaat tggcaaggga
     5701 agaatttcct ggtgaagtcc atgtttttgc accagctttc aaggatgagg acatggagga
     5761 attgcttggg ataacagacc atatcgtctt taactcagag agacagttgc gtaagcatgg
     5821 ttcgcgttgt cgagaggctg gtgtcagtgt tggtttgcgc ctcaaccctc agtgttcaac
     5881 tcaaggagat cacgcgctct atgacccttg tgcaccaggt tctcgctttg gagttactat
     5941 agacaagatt ccgagtgatt tgctagattt ggttgacgga cttcattttc ataccctttg
     6001 cgagcaggga gcagatgatt tacaaacaac tttgaaagca gtagaagaac agtttggtcc
     6061 ctacttacat gaggtaaaat ggctcaatat gggtggtggt catcatatta caagagaagg
     6121 ttacgatgtg gatttgctga tttcagaaat caagcgtatc cgaaaaactt acaatcttga
     6181 aatctatatc gagcctggtg aagccattgc gcttaatgcg ggttatttag caactgaggt
     6241 attagatatt gtagaaaacg gtatggaaat cttggtttta gacgcctctg cgacctgcca
     6301 tatgcctgat gtacttgaga tgccctatcg tccacctttg agaaatggct ttgaggcaca
     6361 ggaaaaagcc catacctaca gactttcttc taatacctgt ctgacgggcg atgtgattgg
     6421 tgattatagt tttgaaaatc cagtccaaat cggagacaga ctttattttc aagacatggc
     6481 catttattct tttgtcaaaa ataatacctt taatggtatt ggattgccaa gtctctatct
     6541 catggacgaa cagggagact gtagcttact caaagctttt ggctatcaag actttaaagg
     6601 gagattatca tgatggacag tccaaaaaaa ttaggctatc acatgccagc agagtacgaa
     6661 ccccatcatg gtaccctcat gatatggccg actcgaccag gatcatggcc ttttcaagga
     6721 aaggatgcta aaagagcatt tactcagatc atcgagacta tagcagaagg ggaaagagtc
     6781 tatcttttgg tggagcaggc ctatctatct gaagcccaat cctatcttgg agacaaggtt
     6841 gtttatttag acattcccac caatgatgcc tgggcgcgtg atactggccc aaccattctc
     6901 gtcaatgaca aaggtaagaa attagccgtg gattgggcct tcaatgcttg gggaggcacc
     6961 tatgatggtc tttatcaaga ttatgaagag gatgaccaag tagccagtcg ttttgctgag
     7021 gccttggaaa ggcctgtcta tgatgctaaa ccttttgtac tggaaggagg cgcaatccat
     7081 agcgatggtc aaggaactat tctcgtaact gaaagttgct tgcttagtcc tggtcgcaat
     7141 cctaacttga ctaaagagga gattgaaaac acattattag aaagtcttgg tgctgaaaaa
     7201 gttatttggc ttccttatgg tatttatcag gatgaaacca atgaacacgt cgataatgtt
     7261 gctgcctttg ttggtcctgc tgaggttgtt ttggcttgga cagatgacga aaatgatccc
     7321 cagtatgcca tgtcaaaagc agatctcgaa ctcttagaac aggaaacaga tgcaaaaggt
     7381 tgtcacttca ccattcataa attgcctatc cctgcagttc gacaagttgt gacagaagaa
     7441 gatttgccag gctacatcta tgaagaagga gaagaagagc gatacgcagg tgaacgacta
     7501 gcagcttcct acgtaaactt ttatatcgcc aacaaggctg tcttggttcc acagtttgag
     7561 gatgtaaacg accaagtggc cttagatatc ctcagcaagt gtttcccaga ccgtaaagtt
     7621 gtcggaatac cagccagaga tattctctta ggtggtggca atatccactg tatcacccaa
     7681 caaattccag aataggagaa aaagatgaga aatgtaagag ttgcaaccat tcagatgcaa
     7741 tgcgctaagg atgtggcaac aaatatccaa accgcagagc gtttagtacg tcaggctgct
     7801 gagcaaggag cccaaattat tctcttgccc gagttgtttg aacatcccta tttctgtcag
     7861 gaacgtcagt atgactacta ccagtatgcc caatctgtag cggaaaatac tgccattcag
     7921 cattttaagg tgattgctaa ggaactacaa gttgttttac caatcagttt ctatgaaaaa
     7981 gatggtaatg tcttgtataa ctctattgcc gtcattgatg cagatgggga agtgctgggc
     8041 gtttatcgaa agacccatat accagatgac cattattatc aagaaaaatt ctatttcacg
     8101 cctggtaaca ctggtttcaa ggtctggaat actcgctatg ctaagattgg tatcggtatc
     8161 tgttgggatc aatggttccc tgaaacagcg cgctgtcttg cattgaatgg tgctgaattg
     8221 ctcttttatc ctacagctat cggttcagag ccaattttgg atacagatag ttgtggtcac
     8281 tggcaacgta ctatgcaagg gcacgcagca gcgaatattg ttccagtcat cgcagccaat
     8341 cgttatggtt tagaggaggt tactcctagt gaggaaaatg gcggacagag ttccagtctt
     8401 gacttctacg gttcctcctt tatgacggat gaaacaggag ctattctaga acgagctgaa
     8461 agacaagaag aagctgttct gttagctact tatgacctag acaagggagc aagtgaacgt
     8521 ctaaactggg gcttgtttcg agatagaaga ccagaaatgt atagacaaat tacagattag
     8581 tgtgggagaa atgagagatt cattctgcta gactaacttc ttattagcaa ctataagata
     8641 ctatggcatc tagtaaatcg atttttatga ttcgctattc ttgtctattg attagtccgt
     8701 attttaaaat attagcaaaa aagcaaatag cagtaacttc tgtctatttg cttttctttt
     8761 ttatagaata tatttctcaa tagcacgcgc aacgccgtct tcttcgttgc ttgaggtaac
     8821 ggcatccgca agagatttga cataatcgct ggcatttccc attgcaatcc caagccctgc
     8881 aaactggagc atttcgatat cgttattagc atcgcccatg gccataatct ctgaggaatc
     8941 aatcttcaaa atctcagcta gtcgtgaaag agcagtagcc tttgtcgttc caagtggcat
     9001 tgcttcataa atgacaggct gcgaacgaac tccactgaat cgttggcaaa gctcttcagc
     9061 aaaacgctgc tcaaaatcgt ctgtttgttc ttttgttcct aaaaacatac cttggaacat
     9121 ccggaacttt ccactagtcg cttcttcaag agaaatttca gtcaggtctg aaaatactag
     9181 tttagcatca ttttcaataa cttgattggg tttgccaccg agaacaaaat aatgtgactc
     9241 gtcaaaaagt gtcaactgaa catcactctt ttcagcaagg tcatagaggt attcgatgtc
     9301 agctggactc agttcttgcc agtcaaccaa gccccagtcg ctagtctggt gagttgaaca
     9361 accgttgtta acaatcacat actcattctg gaggtcgagt cccagttttt tgtagtaggg
     9421 gaggacaccg aaaagggggc gacccgtaca gaggaccagt ttgacacctt tttcaatggc
     9481 ttggtgaata gcagcgatgt gagcctgtgg gatttccttg gcttcattga ggagggttcc
     9541 atccatatcc aaggctagta gtttaatcat aggtcttcct tctttatctt ttggtattat
     9601 tatagcatat tttggagaag aaattgatag aaagtttgag actaattgat tttatagttt
     9661 aagatgtttt gatgacaatt catgatttga agaggatatt tggcaaagat atgctatact
     9721 atgtttgtca atgttgcaac tagacaaatt aaaaaaccaa cttaatataa tagttttttt
     9781 gtaagtaggt atgagtatca gattactcaa ctaatctgaa gaataatgga ggaaatatat
     9841 catgatttta atgacaaaaa atataaatct aacaaatgaa gaattagagc tgatacaagg
     9901 tggagcagat tcatatggta aaaatcctaa tggtaggtac gattgggaaa tagaaccagt
     9961 attaactctg ccggttcatg gattttgtcc cagaggcacc tatgatttag gatatattgg
    10021 aggaggcaat catctttgca aaggaagtgc tgcgagattt taagtaaaat ttattagtaa
    10081 tatgaagaaa caaggggaga aagcagagaa tttaatatga aaaaacgggc tattcaaatt
    10141 ttactagcat tgtccttaat tttttacaaa tcaacttggt tttggagagt tttcaatcac
    10201 ctcgcaaagc cctatctacc agcaagtcgt gaattttttc agattctgct tttgatggag
    10261 agcggagttc ttttcttagc ggtcatctat ctactggttt ttgcaggaaa aaaaattttt
    10321 catttcaagt ggcagctgag gtacttcatc taccttttac tgggctacat catttcatat
    10381 atgtctgact tcctcttttc gtatttcata tccctgtctt caaatcagat ttctttgaat
    10441 gaaacggtag aaatgatggg gagacaggag ttcccttatt tcttgctcat cgtttgcttc
    10501 atcgccccta ttgctgagga attgatttat cgcggtgtgc ttatgacaac ctttttcaaa
    10561 aactcgcctt ggtacggaga tgttttgctt tctgctatta ttttcggtta tattcatatc
    10621 aattttgctt taactcctct tgcttttttc atttatgcta gtggaggtct tattttagct
    10681 ctattgtatc gcatgactaa aaatctctac tatccaatac tagttcatat tctcattaat
    10741 atcactgcct tctgggatgt gtggttgctc ctattttcag gaagttagct tactaaaata
    10801 atgtcggaac tttccggcat tttctttttt cacaaatagt caacgttttt ctttccgata
    10861 ctgaagtggt gtgtagccac ttattttttt gaattgattt tgaaaataag attggcgtga
    10921 gaaaggcaga tagtgaagat agttaagaag aataggatgt tcttttttcc tttttggaaa
    10981 acttctaaaa tatggtataa tgaaaagata aagaagttgg gggtagaaga tgaacattca
    11041 acaattacgc tatgttgtgg ctattgccaa tagtggtact tttcgtgaag ctgctgaaaa
    11101 gatgtatgtt agtcagccga gtctgtctat ttctgttcgg gatttggaaa aagagttggg
    11161 ttttaagatt ttccgtcgga ccagctcagg gactttcttg acccgtcgtg ggatggaatt
    11221 ttatgaaaaa gcgcaagaat tggttaaagg atttgatatt tttcaaaatc agtatgccaa
    11281 tcctgaagaa gaaaaagatg aattttccgt tgctagccag cactatgact tcttgccacc
    11341 aactattacg gccttttcag agcgctatcc tgactataag aacttccgta tttttgaatc
    11401 aactactgtt caaatattag atgaagtggc gcaagggcat agtgagattg ggattatcta
    11461 cctcaacaat caaaataaaa aggggattat gcaacgggtt gaaaaattag gtctggaggt
    11521 catcgaattg attcctttcc atacccatat ttatctccgt gagggtcatc ctttagccca
    11581 gaaagaggaa ttagtcatgg aggatttagc ggatttacca acggttcgtt tcactcaaga
    11641 gaaagacgag tacctttatt attcagagaa ctttgtcgat accagcgcta gctcacagat
    11701 gtttaatgtg acagaccgtg ccaccttgaa tggtattttg gagcggacgg acgcctatgc
    11761 gacaggttct ggatttttag atagtgacag tgttaatggc attacagtta ttcgtctcaa
    11821 ggataaccta gataaccgca tggtctatgt taaacgtgaa gaagtggagc ttagtcaagc
    11881 tgggactctc ttcgtagaag tcatgcaaga atattttgat caaaagagga aatcatgaaa
    11941 aaaagagcaa tagtggcagt cattgtactg cttttaattg ggctggatca gttggtcaaa
    12001 tcctatatcg tccagcagat tccactgggt gaagtgcgct cctggattcc caatttcgtt
    12061 agcttgacct acctgcaaaa tcgaggtgca gccttttcta tcttacaaga tcagcagctg
    12121 ttattcgctg tcattactct ggttgtcgtg ataggtgcca tttggtattt acataaacac
    12181 atggaggact cattctggat ggtcttgggt ttgactctaa taatcgcggg tggtcttgga
    12241 aactttattg acagggtcag tcagggcttt gttgtggata tgttccacct tgactttatc
    12301 aactttgcaa ttttcaatgt ggcagatagc tatctgacgg ttggagtgat tattttattg
    12361 attgcaatgc taaaagagga aataaatgga aattaaaatt gaaactggtg gtctgcgttt
    12421 ggataaggct ttgtcagatt tgtcagaatt atcacgtagt ctcgcgaatg aacaaattaa
    12481 atcaggccag gtcttggtca atggtcaagt caagaaagct aaatacacag tccaagaggg
    12541 tgatgtcgtc acttaccatg tgccagaacc agaggtatta gagtatgtgg ctgaggatct
    12601 tccgctagaa atagtctacc aagatgagga tgtggctgtc gttaacaaac ctcagggaat
    12661 ggttgtgcac ccgagtgctg gtcataccag tggaacccta gtaaatgccc tcatgtatca
    12721 tattaaggac ttgtcgggta tcaatggggt tctgcgtcca gggattgttc accgtattga
    12781 taaggatacg tcaggtcttc tcatgattgc taaaaacgat gatgcgcatc tagtacttgc
    12841 ccaagaactc aaagataaaa agtctctccg caaatattgg gcgattgttc atggaaatct
    12901 gcctaatgat cgtggtgtaa ttgaagcgcc gattggccgg agtgaaaaag accgtaagaa
    12961 acaggctgta actgctaaag ggaagcctgc agtgacgcgt tttcacgtct tggaacgctt
    13021 tggcgattat agcttagtag agttgcaact ggagacaggg cgcactcatc aaatccgtgt
    13081 ccacatggct tatatcggcc atccagtcgc tggtgatgag gtctatggtc ctcgcaagac
    13141 tttgaaagga catggacaat ttcttcatgc caagacttta ggttttactc atccgagaac
    13201 aggtaagacc ttggaattta aagcagatat cccagagatt tttaaggaaa ccttggagag
    13261 attgagaaag taaggatgaa aaagaaatta actagtttag cacttgtagg cgctttttta
    13321 ggtttgtcat ggtatgggaa tgttcaggct caagaaagtt caggaaataa aatccacttt
    13381 atcaatgttc aagaaggtgg cagtgatgcg attattcttg aaagcaatgg acattttgcc
    13441 atggtggata caggagaaga tagacggtag tgattctcgc tatccatgga gagaaggaat
    13501 tgaaacgtct tataagcatg ttctaacaga ccgtgtcttt cgtcgtttga aggaattggg
    13561 tgtccaaaaa cttgatttta ttttggtgac ccatacccac agtgatcata ttggaaatgt
    13621 tgatgaatta ctgtctacct atccaattga ccgagtctat cttaagaaat atagtgatag
    13681 tcgtattact aattctgaac gtctatggga taatctgtat ggctatgata aggttttaca
    13741 gactgctgca gaaaaaggtg tttcagttat tcaaaatatc acacaagggg atgctcattt
    13801 tcagtttggg gacatggata ttcagctcta taattatgaa aatgaaactg attcatcggg
    13861 tgaattaaag aaaatttggg atgacaattc caattccttg attagcgtgg tgaaagtcaa
    13921 tggcaagaaa atttaccttg ggggcgattt agataatgtt catggagcag aagacaagta
    13981 tggtcctctc attggaaaag ttgatttgat gaagtttaat catcaccatg ataccaacaa
    14041 atcaaatacc aaggatttca ttaaaaattt gagtccgagt ttgattgttc aaacttcgga
    14101 tagtctacct tggaaaaatg gtgttgatag tgagtatgtt aattggctca aagaacgagg
    14161 aattgagaga atcaacgcag ccagcaaaga ctatgatgca acagtttttg atattcgaaa
    14221 agacggtttt gtcaatattt caacatccta caagccgatt ccaagttttc aagctggttg
    14281 gcataagagt gcatatggga actggtggta tcaagcgcct gattctacag gagagtatgc
    14341 tgtcggttgg aatgaaatcg aaggtgaatg gtattacttt aaccaaacgg gtatcttgtt
    14401 acagaatcaa tggaaaaaat ggaacaatca ttggttctat ttgacagact ctggtgcttc
    14461 tgctaaaaat tggaagaaaa ttgatggaat ctggtattat tttaacaaag aaaatcagat
    14521 ggaaattggt tgggttcaag ataaagagca gtggtattat ttggatgttg atggttctat
    14581 gaagacagga tggcttcaat atatggggca atggtattac tttgctccat caggggaaat
    14641 gaaaatgggc tgggtaaaag ataaagaaac ctggtactat atggattcta ctggtgtcat
    14701 gaagacaggt gagatagaag ttgctggtca acattattat ctggaagatt caggagctat
    14761 gaagcaaggc tggcataaaa aggcaaatga ttggtatttc tacaagacag acggttcacg
    14821 agctgtgggt tggatcaagg acaaggataa atggtacttc ttgaaagaaa atggtcaatt
    14881 acttgtgaac ggtaagacac cagaaggtta tactgttgat tcaagtggtg cctggttagt
    14941 ggatgtttcg atcgagaaat ctgctacaat taaaactaca agtcattcag aaataaaaga
    15001 atccaaagaa gtagtgaaaa aggatcttga aaataaagaa acgagtcaac atgaaagtgt
    15061 tacaaattct tcaactagtc aagatttgac atcctcaact tcacaaagct ctgaaacgag
    15121 tgtaaacaaa tcggaatcag aacagtagta gaaaagaagg ttttagggcc ttctttttcc
    15181 tatcaactct tttctatttc ctgttattca tgttataatg gataaatatg aataatcgga
    15241 gtgagactat gaaatacaaa cggattgtct ttaaggtggg tacttcttct ctgacaaatg
    15301 aggatggaag tttatcacgt agtaaggtaa aggatattac ccagcagttg gctatgctgc
    15361 acgaggctgg tcatgagttg attttggtgt cttcaggtgc cattgcggct ggttttggag
    15421 ccttaggatt taaaaagcgt ccgactaaaa ttgctgataa acaggcttca gcagcggtag
    15481 ggcagggact tttgttggaa gaatatacga ccaatcttct cttgcgtcaa atcgtttctg
    15541 cacaaatctt gctgacccaa gatgactttg tggataagcg tcgttataaa aatgcccatc
    15601 aggctttgtc ggttttgctc aaccgtgggg caattcctat catcaatgag aatgatagtg
    15661 tcgttattga tgaggtcaag gttggggaca atgacactct aagtgcccaa gtagcggcga
    15721 tggtccaagc agaccttttg gttctcttga cagatgtgga cggtctctat actggaaatc
    15781 ctaattcaga tccaagagcc aaacgcttgg agagaatcga gaccatcaat cgtgagatta
    15841 ttgatatggc tggtggagct ggttcgtcaa acggaactgg gggtatgtta accaaaatca
    15901 aggctgcaac tatcgcgacg gaatcaggag ttcctgttta tatctgctca tccttgaaat
    15961 cagattccat gattgaggcg gcagaggaga ccgaggatgg ttcttacttt gttgctcaag
    16021 agaaggggct tcgtacccag aaacaatggc ttgccttcta tgctcagagt caaggttcta
    16081 tttgggttga taaaggggct gcggaagctc tctctcaaca tggaaagagt cttctcttat
    16141 ctggtatcgt tgaagcagaa ggagcctttt cttacggtga tatcgtgaca gtatttgaca
    16201 aggaaagtgg aaaatcactt ggaaaaggac gcgtgcaatt tggagcatct gctttggagg
    16261 atatattgcg ttctcaaaaa gccaagggtg tcttgattta ccgtgacgac tggatttcca
    16321 ttactcctga aatccaacta ctttttacag aattttagag gtaaactatg gtgagtagac
    16381 aagaacaatt tgaacaggta caggctgtta aaaaatcgat taacacagct agtgaagaag
    16441 tgaaaaatca agccttgcta gccatggctg atcacttagt ggctgctact gaggaaattt
    16501 tagcggctaa tgccctcgat atggcagcgg ctaaggggaa aatctcagat gtgatgttgg
    16561 atcgtcttta tttggatgca gatcgtatag aagcgatggc aagaggaatt cgtgaagtgg
    16621 ttgccttccc agatccaatc ggtgaagttt tagaaacaag tcagcttgaa aatggtttgg
    16681 ttatcacaaa aaaacgtgta gctatgggtg tcatcggtat tatctatgaa agccgtccaa
    16741 atgtgacgtc tgatgcggct gctttgactc ttaagagtgg aaatgcggtt gttcttcgta
    16801 gtggtaagga tgcctatcaa acaacccatg ccattgtcac agccttgaag aagggcttgg
    16861 agacgactac tattcaccca aatgtgattc aactggtgga agatactagc catgaaagta
    16921 gttatgctat gatgaaggcc aagggctatc tagacctcct cattcctcgt ggaggagctg
    16981 gcttgatcaa tgcagtggtt gagaatgcga ttgtacctgt tatcgagaca gggactggga
    17041 ttgtccatgt ctatgtggat aaggatgcag acgaagacaa ggcgctgtct atcatcaaca
    17101 atgctaaaac cagtcgtcct tctgtttgta atgccatgga ggttctgctg gttcatgaag
    17161 acaaggcagc aagcatcctt cctcgcttgg atcaaatgct ggttgcagag cgtaaggaag
    17221 ctggactgga accaattcaa ttccgcttgg atagcaaagc aagccagttt gtttcaggtc
    17281 aagcagctga gacccaagac tttgacaccg agtttttaga ctatgtcctt gctgttaagg
    17341 ttgtgagcag tttagaagaa gcggttgcgc acattgaatc ccacagcacc catcattcgg
    17401 atgctattgt gacggaaaat gctgaagctg cagcatactt tacagatcaa gtggactctg
    17461 cagcggtgta tgttaatgcc tcaactcgtt tcacagatgg aggacaattt ggtcttggtt
    17521 gtgaaatggg gatttctact cagaaattgc acgcgcgtgg tccaatgggc ttgaaagagt
    17581 tgaccagcta caagtatgtg gttgctggtg atgggcagat aagggagtaa gagatgaaga
    17641 ttggatttat cggtttgggg aatatgggtg ctagcttggc aaaatctgtc ttgcagacta
    17701 ggacgtcaga tgagattctc cttgccaatc gtagtcaagc taaggtagat gctttcattg
    17761 cagactttgg tggtcaggct tccagcaatg aagaaatgtt tgcagaagca gatgtgattt
    17821 ttctaggagt taagcctgct cagttttctg aactgctttc tcaataccag accatccttg
    17881 aaaaaagaga aagtcttctt ttgatttcga tggcagctgg attgacctta gaaaaactat
    17941 caagtcttat cccaagccaa caccgaatta ttcgtatgat gcctaatacc cctgcttcta
    18001 tcgggcaagg agtgattagt tatgccttgt ctcctaattg cagggctgag gacagtgaga
    18061 tcttttgtca gcttttagcc aaggctggtc tcttggttga attaggagaa agcttaatca
    18121 atgcagcgac aggtcttgca ggttgtggac cagcctttgt ctatctcttt attgaggcct
    18181 tggcagatgc aggtgttcag acgggattac cacgagaaac agccttgaaa atggcagccc
    18241 aaactgtggt aggagctggg caattggtcc tagaaagcca gcaacatcct ggagttttga
    18301 aagatcaagt ttgtagtcca ggcggttcga ctattgctgg cgtagcaagc ctagaagcgc
    18361 atgcttttcg aggcacagtc atggaggcag ttcatcaagc ctataaacga acacaagaac
    18421 taggtaaata agaggtagct ttgactgcct cttttatggt ggttgatact cttcgaaaat
    18481 caaattcaaa ctgcgtcagc ttcaccttgc cgtactcaag tacagcctgc ggctagcttc
    18541 ctagtttgct ctttgatttt cattgagtat gaaatgagaa gacaaaaaga ttgtcacaaa
    18601 cccctatttt tttgatagaa tagaagtagt aaaaaagaaa tgagttagac atgtcaaaag
    18661 gatttttagt ctctcttgag ggaccagagg gagcaggcaa gaccagtgtt ttagaggctc
    18721 tgctaccaat tttagaggaa aaaggagtag aggtgttgac gacccgtgaa cctggcggag
    18781 tcttgattgg ggagaagatt cgggaagtga ttttggatcc aagtcatact cagatggatg
    18841 ctaaaacaga gctacttctc tatattgcca gtcgcagaca gcatttggtg gaaaaagttc
    18901 ttccagccct tgaagctggc aagttggtca tcatggatcg ttttatcgat agttctgttg
    18961 cctatcaggg atttggtcgt ggcttagata ttgaagccat tgactggctc aatcagtttg
    19021 cgacagatgg cctcaaaccc gatttgacac tctattttga catcgaggtg gaagaagggc
    19081 tggctcgtat tgctgctaat agtgaccgcg aggttaatcg tttggatttg gaagggttgg
    19141 acttgcataa aaaagttcgt caaggctacc tttctcttct ggataaagag ggaaatcgca
    19201 ttgtcaagat tgatgctagt ctccctttgg agcaagttgt ggaaactacc aaggctgtct
    19261 tatttgacgg aatgggcttg gccaaatgaa acaagatcaa ctaaaggctt ggcaaccagc
    19321 tcagtttgac cgttttgtcc gtatcttaga acaagaccag ctcaatcacg cctatctctt
    19381 ttcaggtttc tttgaaagct tggaaatggc gcaattttta gctaagagcc tcttttgtac
    19441 ggataaagtt ggcgtcttac catgtgagaa atgccgaagt tgcaagctga ttgaacaggg
    19501 agagtttcca gatgtcacct tgattaagcc agtcaatcag gtcatcaaga cagaacgcat
    19561 tcgggaattg gtgggacagt tttctcaagc agggattgaa agccagcaac aggtctttat
    19621 catcgagcaa gcggataaaa tgcatcccaa cgcagccaat tctctgctca aggtcatcga
    19681 agaaccccag agtgaagttt atattttctt cttgactagc gatgaggaaa agatgttacc
    19741 gacaatccga agtcggactc agatcttcca ctttaaaaag caagaagaaa aacttatctt
    19801 actcttagaa caaatgggac ttgttaagaa aaaagcgact cttttagcta agtttagtca
    19861 atcgcgagct gaagcagaaa agttggctaa tcaggcaagt ttttggacct tggtcgatga
    19921 aagtgaacgc ctgctgactt ggttagtagc taagaaaaaa gaaagttatc tacaggttgc
    19981 caaattagcc aacttggcag atgataagga aaaacaggat caggttttac ggattcttga
    20041 agttctctgt gggcaggacc tcttgcaggt aagagtaaga gtgattctac aagatttact
    20101 agaagctaga aaaatgtggc aagctaatgt cagctttcaa aatgccatgg aatatctggt
    20161 cttgaaagaa atataaactc aaaaatgaat gataaagaaa ggaaagggct gttttatgga
    20221 caaaaaagaa ttatttgacg cgctggatga tttttcccaa cagttattgg taaccttggc
    20281 cgatgtggaa gccatcaaga aaaatctcaa gagcctggta gaggaaaata cagctcttcg
    20341 tttggaaaat tctaagttgc gagaacgctt gggtgaggtg gaagcagatg ctcctgtcaa
    20401 ggccaagcat gttcgtgaaa gtgtccgtcg catttaccgt gatggatttc acgtatgtaa
    20461 tgatttttat ggacaacgtc gagagcagga cgaagaatgt atgttctgtg atgagttgtt
    20521 atacagggag taggcatgca aattcaaaaa agttttaagg ggcagtctcc ctatggcaag
    20581 ctgtatctag tggcaacgcc gattggcaat ctagatgata tgacttttcg tgctatccag
    20641 accttgaaag aagtggactg gattgctgct gaggatacgc gcaatacagg tcttttgctc
    20701 aagcattttg acatttccac caagcagatc agttttcatg agcacaatgc caaggaaaaa
    20761 attcctgatt tgattggttt cttgaaagca gggcaaagta ttgctcaggt ctctgatgcc
    20821 ggtttgccta gcatttcaga ccctggtcat gatttggtta aggcagctat tgaggaagaa
    20881 attgcagttg ttacagttcc aggtgcctct gcaggaattt ccgccttgat tgccagtggt
    20941 ttagcgccgc agccacatat cttttacggc tttttaccga gaaaatcagg ccagcaaaag
    21001 caatttttcg actcgaaaaa agactatcct gaaactcaga ttttttatga atcgccccat
    21061 cgtgtggcag atacattgga aaatatgcta gaagtctacg gtgaccgctc cgttgtcttg
    21121 gtcagggaat tgaccaaaat ctatgaagaa taccaaagag gtacaatttc tgaattgctg
    21181 gaaagcattg ctgaaacgtc tctcaagggt gaatgtcttc tgattgttga aggtgccagt
    21241 caggatgtgg aagaaaaaga cgaggaagac ttgttcttag aaatccaagc tcgtatccag
    21301 caaggtatga agaaaaatca agctattaag gaagtcgcta agatttacca gtggaataag
    21361 agtcaactct acgctgccta ccacgactgg gaagaaaaac aataaaggga gacaggatgt
    21421 aataattctg tctgtttctg tttaacttaa ttagtgatga taatataaag atgtatcact
    21481 tggtatagaa gctttggtat taagtttttt attaagccca tacggaatac cgatggttgg
    21541 agcagcagtt atagcgttct tagaaggtat aaatagaaaa ataaggtcat tttaaatcaa
    21601 aggattgata aatcagaaag aaggtgattt tttgcgaaca tacgaaaata aagaagaact
    21661 aaaagctgag atagagaaaa catttgagaa atatatttta gaatttgata atattccaga
    21721 aaatttaaaa gataagagag ctgatgaagt tgacagaact ccagcagaaa accttgctta
    21781 tcaggttggt tggaccaact tggttcttaa atgggaagaa gatgaaagaa aggggcttca
    21841 agtaaaaaca ccatcggata aatttaaatg gaatcaactt ggtgaattat atcagtggtt
    21901 cacagatacc tacgctcatt tatctctgca agagttgaaa gcaaaattaa atgaaaatat
    21961 tcattctatc tctgcaatga ttgattcgtt gagtgaggaa gaattatttg aaccgcatat
    22021 gagaaagtgg gctgatgaag cgactaaaac agcgacttgg gaagtgtata agtttattca
    22081 tgtaaatacg gttgcacctt ttggaacttt cagaactaaa atcagaaaat ggaagaagat
    22141 agtattataa attatatttt taactttaaa aaatttcata aaaatggtta ccaaaggcga
    22201 tagaagaaaa actatcgtct ttttctttgc aaatttttaa gaagggaggt gatcttgcat
    22261 ggactttgaa tatttttata acagagaagc gaaaagattt aacttcttaa aagtaccgga
    22321 gatattagtt gatagagaag aatttcgggg cttatcagca gaagcaatta tcctttattc
    22381 catacttctt aaatagacag gaatgtcatt taagaataac tggatagaca aggaaggcag
    22441 agtatttatc tattttactg tcgaagaaat tatgaaaaga agaaatatct caaagccaac
    22501 tgccataaaa acattagatg agcttgatgt aaaaaaagga ataggactga tcgaaagagt
    22561 aaggcttgga cttggtaagc cgaacatcat ttatgttaaa gactttatga gtatatttca
    22621 ggtaaaagaa aatgacttac agaagtcaaa aaacttaact tcagaagtaa aagattttaa
    22681 cctcagaagt aaagaaaatg aacttcaaga ggttaagaac cttgactcta actatataga
    22741 gaataataag agtaagtata gtaagagaga atatagtttt ggtgaaaacg gacttggaac
    22801 atttcaaaat gtgtttttag ctgctgaaga tatatcggat ttacaaatca taatgaactc
    22861 acagcttgag aattacatta gacttcctgc aaaacta
//
LOCUS       DAVMCN010000024        22737 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVMCN010000024 DAVMCN010000000
VERSION     DAVMCN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.024"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..983
                     /locus_tag="VYP85_001165"
                     /pseudo
     CDS             1..983
                     /locus_tag="VYP85_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1111..2133)
                     /gene="cbpF"
                     /locus_tag="VYP85_001166"
     CDS             complement(1111..2133)
                     /gene="cbpF"
                     /locus_tag="VYP85_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1881691.1"
                     /translation="MKLFKKMMQVVLATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2152..2973)
                     /gene="cbpG"
                     /locus_tag="VYP85_001167"
     CDS             complement(2152..2973)
                     /gene="cbpG"
                     /locus_tag="VYP85_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1881692.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3054..3293)
                     /locus_tag="VYP85_001168"
     CDS             complement(3054..3293)
                     /locus_tag="VYP85_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881693.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3443..3709)
                     /locus_tag="VYP85_001169"
                     /pseudo
     CDS             complement(3443..3709)
                     /locus_tag="VYP85_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3734..4045)
                     /locus_tag="VYP85_001170"
     CDS             complement(3734..4045)
                     /locus_tag="VYP85_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1881694.1"
                     /translation="MDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSLWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3970..4212)
                     /locus_tag="VYP85_001171"
     CDS             complement(3970..4212)
                     /locus_tag="VYP85_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1881695.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(4213..4845)
                     /locus_tag="VYP85_001172"
     CDS             complement(4213..4845)
                     /locus_tag="VYP85_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881696.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4859..5854)
                     /locus_tag="VYP85_001173"
     CDS             complement(4859..5854)
                     /locus_tag="VYP85_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1881697.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5851..6549)
                     /locus_tag="VYP85_001174"
     CDS             complement(5851..6549)
                     /locus_tag="VYP85_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1881698.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6626..7636)
                     /locus_tag="VYP85_001175"
     CDS             complement(6626..7636)
                     /locus_tag="VYP85_001175"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1881699.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIVDLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7620..8627)
                     /locus_tag="VYP85_001176"
     CDS             complement(7620..8627)
                     /locus_tag="VYP85_001176"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1881700.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGRLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVFLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8614..9567)
                     /gene="mvaD"
                     /locus_tag="VYP85_001177"
     CDS             complement(8614..9567)
                     /gene="mvaD"
                     /locus_tag="VYP85_001177"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1881701.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9549..10427)
                     /gene="mvk"
                     /locus_tag="VYP85_001178"
     CDS             complement(9549..10427)
                     /gene="mvk"
                     /locus_tag="VYP85_001178"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1881702.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVS
                     AESPWRLYEEDTLSMAVYASLEYLDITEACVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10549..10878)
                     /locus_tag="VYP85_001179"
     CDS             complement(10549..10878)
                     /locus_tag="VYP85_001179"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1881703.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
     gene            11205..11963
                     /locus_tag="VYP85_001180"
     CDS             11205..11963
                     /locus_tag="VYP85_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1881704.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            11974..12768
                     /locus_tag="VYP85_001181"
     CDS             11974..12768
                     /locus_tag="VYP85_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1881705.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            12781..13458
                     /locus_tag="VYP85_001182"
     CDS             12781..13458
                     /locus_tag="VYP85_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1881706.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            13468..14127
                     /locus_tag="VYP85_001183"
     CDS             13468..14127
                     /locus_tag="VYP85_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1881707.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            14385..15575
                     /locus_tag="VYP85_001184"
     CDS             14385..15575
                     /locus_tag="VYP85_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1881708.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(15896..16777)
                     /locus_tag="VYP85_001185"
     CDS             complement(15896..16777)
                     /locus_tag="VYP85_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1881709.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(16918..18246)
                     /gene="vncS"
                     /locus_tag="VYP85_001186"
     CDS             complement(16918..18246)
                     /gene="vncS"
                     /locus_tag="VYP85_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1881710.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(18243..18899)
                     /gene="vncR"
                     /locus_tag="VYP85_001187"
     CDS             complement(18243..18899)
                     /gene="vncR"
                     /locus_tag="VYP85_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1881711.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(18948..19031)
                     /gene="pep27"
                     /locus_tag="VYP85_001188"
     CDS             complement(18948..19031)
                     /gene="pep27"
                     /locus_tag="VYP85_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1881712.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(19211..20590)
                     /gene="vex3"
                     /locus_tag="VYP85_001189"
     CDS             complement(19211..20590)
                     /gene="vex3"
                     /locus_tag="VYP85_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1881713.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(20642..21289)
                     /gene="vex2"
                     /locus_tag="VYP85_001190"
     CDS             complement(20642..21289)
                     /gene="vex2"
                     /locus_tag="VYP85_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1881714.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(21302..22579)
                     /locus_tag="VYP85_001191"
     CDS             complement(21302..22579)
                     /locus_tag="VYP85_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881715.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         6583 a         5156 c         4169 g         6829 t
ORIGIN      
        1 tcgttactat tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggctg
       61 gactaaagat agagtttctc ttgaatactg cctcccaagt cgtacgatac ttcttaactg
      121 gctagcacaa tacaggaaaa acgggtatac tattgttgag aaaacaagag ggagagtacc
      181 tgagagcgga gaatgctatc ctaaaaaagt taagagaact ccgattgaag gaggaaaaag
      241 agaaagaaga aagacagaaa ttgttcaaga attaatgact gaattttcgt tagctcttct
      301 tctaaaagtc attaaactag ctcgttcgac ctactactat cacttgaaac agctagacaa
      361 accagataag gaccaagagc ttaaagctga aattcaatcc atttttatca aacacaaggg
      421 aaattatgct tatcgccggg ttcatttaga actaagaaat cgtggttatc tggtaaatca
      481 taaaagagtt caaggcttga tgaaagtact caatttacaa gctaaaatgc gacagaaacg
      541 aaaatattct tctcataaag gagacgttgg caagaaggca gagaatctca ttcaaggcca
      601 atttgaaggc tctaaaacaa tggaacagtg ctacacagat gtgactgaat tttccattcc
      661 agcaagtact caaaagcttt acttatcacc agttttagat ggctttaaca gcgaaattat
      721 cgcctataat ctttcaactt cacccaactt agaacaagta aaaacaatgt tggaacaggc
      781 attcacagag aagcactatg gtggagtcct tctttgggat tctgaaatcg gaaatgtttt
      841 atggctatga gaaaacattt aaatcactta atcaattgga acaagccatt atagactata
      901 ttgattatta caacaacaag agaattaagg taaaactaaa aggacttagt cctgtgcagt
      961 acagaactaa atcctttgga taaattattt gtctaacttt tggggggcag tacagaaaaa
     1021 ccttgatact atgcgttttt tgattgtgaa gacttttatc cacctattat acaaagttaa
     1081 gtatccatca cagtttacaa ttagccttca ttacttaacc cattcaccat tatagtttaa
     1141 gtagtaacca cctactgtgg tattaacagc taaagcacct gaatcatagg catagtacca
     1201 gttaccattg acttggaacc agcctgtttt catatctcca ttacttgcat ttagatagta
     1261 ccaagtcgaa ccttcctgat accaaccagt tgccatagct cctgatgaac ggagatagta
     1321 ccatttgttc ccaaggtttt gccagccagt tctcatatca ccattttcag catctagata
     1381 gtaccaagtt gagccttcct tataccagcc agttgccata gctcctgacg aatggaggta
     1441 gtaccactta ttacctagat attgccaacc tgtttgcata atgccagttg ctggatctag
     1501 gtagtaccat ggagctgctt ttagcttctc ttcatcatag gtaagagggt aatccttaac
     1561 ccaaccacgt gctagctctc ccaccgtcaa tctgttgatg cgcgaatcaa agccaccatc
     1621 cttctgtaaa taataccaat gaccctcttc ataaatccaa ccagttttta aagtatgata
     1681 actacgctga tcttcaaaat aatagactcg tttctctgct gggctatcat attcttcccc
     1741 atgatgtttg ttggtattcg tagcagtttt tgcttctaaa acttgcttgc caacaaattc
     1801 ttgtaataca ccatcttgac caaaataaaa ccaatctggt ctaagagcaa tctctattct
     1861 tggagaagga ccaatcgtaa cccccttgtg tggagcaggt atatattgcc agccgacaac
     1921 catctctccg gataaaggat caaaataata gtacttccca tctatcactc tccagtaggt
     1981 ttcttttaga tccccctttt tgtagtaggt tcttccgttt tcttggacaa actgccatcc
     2041 ttcagaatca tctgcaaata ctgtactggt ccctagcaaa ccgaagaaaa atgtggctag
     2101 tacgacttgc atcatttttt taaaaagctt cattttatat atcctccaac atcaaatcca
     2161 ctcaccagat gaagcgaagt tataaacttt accatcgata gtttggctac ctgtaaccat
     2221 tgctctattt gaattgagat aataccattt tccatttact ttttgccaat ctgtaagcat
     2281 cttaccggaa ctgtctaaat aataccaagt atcatttatc tcctgccaac ccgtttgttt
     2341 atcatgttgt ctataatagt accaactacc atttattttc ttccatcctt caagagagta
     2401 acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa ctgcactgtt
     2461 aatttgatta gctccatctc ctaaagtatg cactcctact acgcggtgac tagcatcata
     2521 aactgcagat ccactagacc cctctaaagt atcaacttgg taatccaaga acatgccatc
     2581 atcacttaaa acttgttttt tatctgtata catttgatga attttaaaat tatatgatag
     2641 atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag gaagacccaa
     2701 agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt catattccct
     2761 tgcattctta gaatttaaat ttctaaattc cttcaaataa cgaacttcct ttactttgat
     2821 ctttccaaat agttcttgac ttggactaac agccggaaga acataaatat catccgcttc
     2881 tttcccatag tcatgtctgt agtagttgtg agccgctgta attaacacat tatctttaat
     2941 aaaattcgca cttcccctcc cttctacatt cattccatcg gctactccat aatacttaga
     3001 taaaaccata gctgaagtcg aatacggata ctgtaaagta ttatcaattt taatcaaatc
     3061 atcattaccg ataatacttc tgattgcttt tggtagtatg aaccatacgt tggtgaaatc
     3121 tcagataatg aagaatcatt agactctgga cctttttcta gtgtctcact tacctcatat
     3181 tcttcacctg tactagaaat aacactcaaa gcagatactg tcgataactg gctagccaat
     3241 aaagtactcg caataattga aatacccaat tttttataaa cagttttctt cattatcgta
     3301 tcctcctaat gtaattatag cgtactattc taaatttctc aatctactat agaatcaaga
     3361 aatctaccac cttctttaaa taccctccat tatcacataa acaggtaaac ttttcaatta
     3421 atgactgcgc ttttcaatca cgctagaggt acttgcttgc ttctttgata ctaagttcag
     3481 ccattctttc cttgtttttc tcaataaagc atgttaccca agtgggattc gttttggagt
     3541 agtctcgcag agtccagcca atggctttat tgataaaaaa ttctgtttgg ttcaagttat
     3601 gaaggagaat cttttccatt aattgagtat tggtcttctc ttttcttaac aactggtggt
     3661 caatagcgac acgtctcagc cagatattat ctgataggct ccattttata ctcaatgaaa
     3721 atcaaagagc aaactaggaa gctagccgca gattgctcaa aacactgttt tgaggttgca
     3781 gatagagctg acgtggtttg aagagatttt cgaagagtat taagattatt tcttctagtt
     3841 cagggtgttc atacaccaaa ctccctacta ctcgatctag gatatctacc gtgtcccaca
     3901 aggattttgt cacgactaac tgctctagct taggcaaatc ggtttccttt agataagact
     3961 gcattgcttt caaatagtta gcagccacat attggtattt tctaggatcc ttttcccagc
     4021 aagtgtctgc aaaatcccaa tcgataatct ttgttttttt cgcttctgga aaatattttt
     4081 atagagttta tttctttcag gcaccgcaat acctagaaaa gaaaattgat ggcgcatata
     4141 ggcttccatg gaccttgctt ttttagagtc ttttgctgct tctagctcct caagtaaatc
     4201 tgctaaactc atctaaaact cctcttgccc caccaaatgg tgctgaaagg catagacagc
     4261 cgcctgggta cgatcgctga cttcaagttt ggcaagaata ttggacacgt gggtcttgac
     4321 cgtcttgaga gagataaaga ggtcatctgc gatgcgctga ttttcgtagc ccttggcgat
     4381 gagttggaga acatctcgct cacgcgcagt caattcttca tgaagttcca tatgattgcg
     4441 gtggtattca accttcttgc taacctcttg ctcaatggcc agctcgccag cagctacctt
     4501 actgacggca tgaagcaatt catctgcact agaagtcttg agcatatagc ctttggcacc
     4561 agcatctaag actggcatga ttttttcatt gtccaaataa gaggtcacaa tcaaaatctt
     4621 ggcttcaggc cattctttaa ggattgctaa ggtcgcgtca attccattca tctcaggcat
     4681 gacaatatcc atgacaatga catctggacg cagttccaag gccaagtcaa tcccttgaga
     4741 cccgttggac gcctcaccca caacttctac atcgtcttgg aggtcaaagt agcttttcaa
     4801 acccaaacgg accatttcat ggtcatctac tagtaaaatt ttcatcttta ctcctttatc
     4861 attccttatc taacagggga atacggatat caactgccag cccttgcttg ggagctgtta
     4921 ataactgaac cgtccctgcc atatcttcaa cccgctcctt gatatttcgc agtccataac
     4981 tcaagtcgtc taagctccct aactggaaac caatcccatt gtccaccacc ttcagttgca
     5041 attcaacatc tgtctgatag aggtagacat ctaggcaaga tgcctgggca tggcggaggg
     5101 tattgctaat caactcttgc aggatacgga agatatgctc ctcgattttc ttaggcaatt
     5161 tcgtcatatt ctgcttgaga ctaaccctaa gatcactctt gtcctcaagc tcttttaaga
     5221 gaatttgaat cccttctatc aagctcttct gctccagttc aactggtcgc aaatgcaaga
     5281 gcaaaacccg caaatccttc tgggcagttt ctaaaatagc tgtgacactc tgcaactgga
     5341 tctgcatctt ttctctatcc aatttcaaag cttgctgact gatacccgat aaaatcatgt
     5401 gggccgcaaa caactcctga ctgactgtat cgtgcaaatc ccgagcaatt cgcttccgtt
     5461 ctttctcgat gatttcctct tcctgagcaa ggctatgatt ttcagctttt tgaagagcct
     5521 ctgtcaaaag gttaagttta cctgataagg acttgaaact ggcatccaaa tctggatctg
     5581 caacctgaac cacttcttgc cctgctaata aacgcttgag attagcctgc atttttctta
     5641 gagaaagctc ttcgatccct cgccaaaaca gggctaagag acaggtcatg gacatgctga
     5701 aaaccaacaa taaaaagaca aatttttctg ttttttcgac atcgtacaaa aagatagacc
     5761 agtcaaaatc aagtatttcc agcaagctgt gggagaaaaa aaagacaaat aggaaggagg
     5821 tgagagcaat aatgacatag gcttgttttt tcatcctcta accacctcca catcaccaat
     5881 catagtggtc aagaaaatct tgacactctt gttactcttg agatagtctt ttgtttcttg
     5941 atgatagtgt tcattgcgga gggctcgctt gggctggttg aaaaaagtca aatccccata
     6001 gagacagtta acgctgagac tgacttccac atctacaggt acgatgattt tggtcgttcc
     6061 taccatcttt ctgaggataa tgacattgtc atgattggtt aagatgaccc tctccagatg
     6121 aatagtgtcc ttgcccatga agcgaaagag attgatatca tcgaattggc aagtctggta
     6181 gcttgaaaaa tgatgaagat ttccaaacca acgatttttc tccttcttaa ccgtcacgac
     6241 ctcttcaaaa accaaattgg tctgctcttt ttcctggttc atcatcgggt aaagaagaaa
     6301 gagactatag ataaccgcaa caaaaatagc tagaatcaca aaaggattga gcataacgat
     6361 gaaaaagaag agaatggttg ccgctactaa aagaagatta tttccctctt taccagtgta
     6421 gtagcgaatc aaaagcaaaa agaggaatag tatcagcaga aaacgcgaaa aatgctctga
     6481 taccatcaaa atcagagctc ctgtcagaag acaggcttcg ataaataaaa agattttaaa
     6541 ttttctcata ggttcatcct ctcccttcta ttttatcaca attcaaaaaa gtcacctcag
     6601 tctgaggatg gaaaaaaggc gctggttacg cctttttcat ctgatcattt gcttctttta
     6661 attttccata aagaagatag tctacttttt gtagatctac tatggtggca cagttaaggg
     6721 aacacataat caagcgtagg tctgctttcc agccttggac aatgccaatc acttcttcaa
     6781 ctgtgtaggt ttcaaccaat tccagaacgg ttcgtgacaa tcccacagac ttagcaccaa
     6841 aaaccaagca cttaatcata tccagcggat tccgaacccc tccactaacc aagagttcga
     6901 ccttatcttt ccattcttgg gcattgagaa gggcctgcat ggtagactga ccccattgat
     6961 tgaggtaatc acgctggcca ctacgacggt tttcgatata ggcaaagctg gtgccaccac
     7021 gacccgatag gtccactgta cgaacaccga attcataggc tctttcgatt gtcttggcat
     7081 ccattccaaa gcccacttcc ttgaggacaa taggaacggg aatttgcttg ctataatctg
     7141 ctagatgcga ttgccagctt ctaaacttcc tttctccctc gggcatgagt aattcctgca
     7201 tgacattgac atgcacttgc aatagaacag gattcatctc ttctacagtc tgaagtccta
     7261 actcgacagg tttgtccaat ccaatattgg ttccaaggag gagattggga tgactagact
     7321 tgacagaaaa agaatcatcc gttggatttt tgagggctgc gctataagaa cccgttacaa
     7381 ataaaatacc acaggattcc gccacctgag ccagcttttg attgatttct cttcccttat
     7441 tacttccacc agtcatggca ttgatataaa aaggaaagtc ccactttcga ccagcaaact
     7501 ctgtcgaaag atcgatttca tccagattgt aaagaggcaa ggaagaatga atcagctcca
     7561 cctcatcaaa gctattatag gaacttttct gctcaagggc atagaggata tgctcgtcct
     7621 tacgatttgt cgtcatgtcc tatcctttct tgatataaga gctcaatccc cagatcggcc
     7681 caacgatttt ttaaggtttt ggttgattgc gcatcaaaac tcagggcgat gccacagtca
     7741 ccaccaccag caccactact cttggcaacg gcctgcaaat cttgactggc ttctttcaac
     7801 tgtctaagca aaggcgtgta aatatctgta ctcaagcctt ctaaaagctt gctggctact
     7861 tctacttgct cgataacttt ttcggctttc ccctgctcca aggcttcgac caaaaaaacc
     7921 accgtttctt ttgaggaagt taaaaaattt tgattgatat tttgcttgat ttgctgaacc
     7981 atgtgactcg atacagccac ttccttggtc catcccacta agaaatcaca ttctaaagtt
     8041 ggtttcactt gtgagataaa aaatccccaa tcacgctcca gaactgtcgc caagttttct
     8101 tcttctaacc aagcagccgc cttctggcga tcaaatgact ggtagagaac caaatcctct
     8161 gccacaatac aggcaaggtc gcccatggaa ccattgtctc ctcgcttgag caagacagcg
     8221 ctagtcagct tgaacaagag ctcctgatca acagaaacat catacagagc cagtaaagcc
     8281 ttgacaacca agacaacgac gctgccacta gaacctagac caaacttttt cccttctcgt
     8341 tccattttgc cacagatttc tagagaaaaa ggtcttaaat tctgaccgcg aacagcgagg
     8401 aagtctccca tcaaagcaat cgtttcttga atcaagctgt agtcaggatt gggccttaag
     8461 tccactgcga aatcaaacat atctgaatag atacggtagc tgtcagaaaa agcaatctca
     8521 gccctcatat agatgggaat atcctttatc aaagctaacc gccctggctc taaaatagca
     8581 tattcacctg ccaaatagag ttttccgcaa gttttaacag caatcatctt gactcaaatc
     8641 ctttgttttt gacacaatca agcgataacg ctgaccgaaa atttctgaca aatgctccaa
     8701 gtctttctcc tgacagaaga ccttaacatt gggaccagca tccatggtaa agtagcaggc
     8761 ctctcctttc tcacgaagct gacgaacaaa ggccatagcc tcataagagg catccgtcag
     8821 ataagaaaag gctggactag cagtctttgt cgtagcatgc atagccaggg catttttctc
     8881 cgttaattct ccaatcttgg caaaatcatt ttccttgaga taaatcagca tatcctgata
     8941 gtccttctca gactgacgaa cccagtcgtc gaaagtcgtc gaggtttcca cacaaagttt
     9001 catcccgtca cggctagaga ttggtttttt cttgtcctct agcaccaaca taatcatagc
     9061 tagtttcaag tctgtctcta cagggtaaat ttctccacta tccttatccc aggctcctag
     9121 tggtccataa aaactccgag aagaagagcc tgaggcaaat ttggcttcct gtgccaactg
     9181 acttctatcc aatccaagtt tgaaataagc attacaagcc ttgaccaggg cggacaaacc
     9241 actagaactt gaggacaggc ccgctgccgt aggcatattg ttttgagtat cgatacggac
     9301 aaagccctca ccagctggac gataacggtc aataatctta ctcatcttgg catgctcgac
     9361 ctcattttgt agctgaccat tgatgtaaaa ttcgtcagct gttacattgg ctggtaaagg
     9421 cgacaaggtc gtctctgtat acatattttc caaagttaga gaaatactgc tagtagcagg
     9481 caccatctct ttttcttttt tctttcccca atatttgata atagcaatat ttgcgtagga
     9541 acgtactgtt acaggctctc tatccatgtc tgaacagctc ctttctcttc taatctttct
     9601 gctagttctt gtgcgtgtgt caaattggtt accaaggcta tgatacaacc tcctagccca
     9661 ccaccgctca tcttggcacc cagagcacca tggctaagag tcgtttcaac caaaaagtct
     9721 gcctcagggc tactgactcc aatttctttt aaatgtaaat gcgcttgact gaggatttgt
     9781 cccagtcctt cagcatcttt ttgtgaaatc gcaacttctg cttgctgggt taattctccc
     9841 aaggcatgca aaaacggtag ggcatccttg cccttatttt gaaccacttg gatggcttca
     9901 cgagtatgac cataaacacc cgtatcggca atcaccaaat aggcggataa atccatctca
     9961 agttctgtaa atcctacgtt cttgataaag cgaataggtt ggtcactgag acaggtctta
    10021 gcatccaaac cactaggatt catatgggca atcatctcag ctcgattgac caagatttct
    10081 agtacatcat gaggcagatc agcctgatag tagtcaaata ccgcacgaat ggccgctatg
    10141 ctgatagccg ctgacgaacc catcccccgt ttctcaggga tagccgagtc aatctcacaa
    10201 cgaacgcagg cttctgtgat atccaaatac tccagtgagg cataaaccgc catggacaag
    10261 gtatcctcct cataaaggcg ccaaggactc tctgcagaaa ctaccttaca ggtcacctcc
    10321 acctccaaaa gaggcaggga aatggcagga taaccgtaaa cgaccgcatg ttcccctatt
    10381 aaaattatct tactatgtgc ctgaccgaca ccaacttttt ttgtcatttt ttccttttac
    10441 tagacgaaaa aacgtcttat ttttcataca agtattaatt ctttcctatc tattttatta
    10501 tattttcaca aaaaaagcga ttgtttccat tcacaatcgc ttctttcatt attgaaccca
    10561 ttcgccatta taattgacaa aatagccatc tacggtcgta ttcactgcca aggcacctga
    10621 gctataagcg tagtaccatc tgccattgac ctggaaccaa cctgtcgtca tagaacgacg
    10681 aaagaaactc cataccatta agtaaagagg aaagtcgtga gggagcatgc gccattgaca
    10741 acctgtttta gtgacgtaca aagtctcatt aacaagtact cgtttcggcc atttataggt
    10801 gcggtgtttg gagaaatagg gttcaatctt agcccattct tgatcgttta aatcagtatc
    10861 atatactttg cgtgtcataa ctctagttta acattttttg tgaatacagg ttctaaataa
    10921 tcgaccacga aaatttctta agtggaaaac gccttatgaa gtatgctacg ggaaagttat
    10981 gcacttaatt tgacaattca agatgtaaaa atatatacta tagtagattg aaactagaat
    11041 agtacacctc tacttctaaa atattgttag aaatcgattt gactgtcccg atcgatttgt
    11101 cctgttctta tttcactata gtgaattttt tcagatatgg tttgacaaga acattctttt
    11161 attgtagaat cgtgttataa aatctaacac aaaggagatc tctcatggct ttagtagaat
    11221 ttaaaaacgt cgaaaaatat tacggagact accacgcact ccgcaacatc aatctccgtt
    11281 ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag tccactctta
    11341 tccgtacgat caatggttta gagactgttg acaaaggaag tctcctagtc aatgggcacc
    11401 aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc ggcatggttt
    11461 ttcaacattt taacctttat ccacacaaaa ctgtgttaga aaacgtaaca cttgcaccca
    11521 ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa tatctggaat
    11581 ttgtaaatat gtgggacaag aaagattcct atcccgccat gctatctggt ggacaaaaac
    11641 agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc tttgatgaac
    11701 caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg cagaaactgg
    11761 cgcatgatgg gatgaacatg atcatcgtta cccacgaaat gggctttgct cgagaggttg
    11821 cggaccgcat tatctttatg gccgacggag aagttttagt agatacgaca gatgtcgata
    11881 acttttttga caatccaagc gaacctcgtg cccaacaatt cctcagcaaa attatcaacc
    11941 acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaaattctt tttatcagca
    12001 ttattgatta gccttttcgg ccttgctgct gccaaaccag tccaggctga tactagtatc
    12061 gcagacattc aaaaaagagg cgaactggtt gtcggtgtca aacaagacgt tcccaatttt
    12121 ggttacaaag atcccaagac cggtacttat tctggtatcg aaaccgactt ggccaagatg
    12181 gtagctgatg aactcaaggt caagattcgc tatgtgccgg ttacagcaca aacccgcggc
    12241 ccccttctag acaatgaaca ggtcgatatg gatatcgcga cctttaccat cacggacgaa
    12301 cgcaaaaaac tctacaactt taccagtccc tactacacag acgcttctgg atttttggtc
    12361 aataaatctg ccaaaatcaa aaagattgag gacctaaacg gcaaaaccat cggagtcgcc
    12421 caaggttcta tcacccaacg cctaattact gaactgggta aaaagaaagg tctgaagttt
    12481 aaattcgtcg aacttggttc ctatccagaa ttgattactt ccctgcacgc tcatcgtatc
    12541 gatgcctttt ccgttgaccg ctctattcta tctggctaca ctaataaacg gacagcacta
    12601 ctagatgata gtttcaagcc atctgactac ggtattgtta ccaagaaatc aaatacagag
    12661 ctcaacgact atcttgataa cttggttact aaatggagca aggatggtag tttgcagaaa
    12721 ctttatgacc gttacaagct caaaccatct agtcataccg cagattaagg aggataccct
    12781 atgacagatt tatcatcttg gacagcctat tttcaggatt ttggacaatt tttcaatggt
    12841 ttcctcttta ctcttgccct agcgattgga tcctttatcc tcgccatggt cttaggaatc
    12901 ttctttggtg ccatgtcaac cagtaaacgt ccaattttac gcattttagc tcgcatcttt
    12961 gttgaatttt accaaaatac tcccctcttg gtgcagtttg ttattgtttt ttatggccta
    13021 cctcttatca gtgaccatat catcatgatt ccaatttatt ggacagccgt tctctgcgtg
    13081 ggactctatc acggcgctta tatcgctgag gttattcgtt cagggattca gtctattcct
    13141 agtggtcaga tggaggccgc cttgtcgcaa ggttttacct atatcagtgc catgcgcttg
    13201 attatcttgc ctcaggcctt ccgcatcatt ctccctccat tgaccaacca aattgttaac
    13261 ctcatcaaga acacctctac tgtagctatc atctctggag tagacttgat gtttgtgact
    13321 aagtcttggt cggctctcaa cggaaactat atcccagcct ttttaggtgc tgctcttctc
    13381 tactttgccc tatgcttccc tgttgcccag tttggtcgca agatggagca agccaacaaa
    13441 aaagcctatt cactttagga ggttactatg gaatctattt tagaagtttt aaccccagat
    13501 aacctagtct ttatctttaa aggatttggc ttgaccctct atatttctct gattgccatc
    13561 atcctctcta ctatcatcgg tacggtgcta gctgtcatga gaaatggcaa aaatcctgtc
    13621 ttgcgaatca tctccagtat ttatatcgag tttgtgcgca acgttcccaa ccttctctgg
    13681 atttttacta tctttttggt gttcaaaatg aaatccacac cagcaggtat tacagccttt
    13741 actctcttta catcagcagc cttggttgag attattcgag gcggtctcaa tgccgtagac
    13801 aagggacaat acgaagcagg aatgtcacaa ggcttcacct cagcccaaat cctctactac
    13861 atcattctcc cacaagccat ccgcaaaatg ctaccagcca tcatttctca gtttgttacc
    13921 gtgattaagg ataccagtct cctctactct gttatcgccc tacaagaact ctttggagcc
    13981 agccaaattc tcatgggccg ttattttgaa ccagagcagg tcttcagtct ttacatcctg
    14041 attgccctca tctacttcag ctttaaccta gcaatttcta gcctgtctca tatgctagcc
    14101 aaacgttggc aacaagctgc agaataatac tcttcgaaaa tctcttcaaa ccacgtcagc
    14161 tctatctgca acctcaaaac agtgttttga gcaacttgcg gctagcttcc tagtttgctc
    14221 tttgattttc attgagtata aacagccact ctccagttca attggagagt tttttgatga
    14281 gagtagatat ttatagacct caatttgaca ccatacattt tctatgataa aatgtaacaa
    14341 attcatttac aacaaatcga aatctaaatg aaatggaatt ttctatgaaa tcagtcaaag
    14401 gactactctt tatcatagct agttttatct tgactctttt gacttggatg aacacttctc
    14461 cccaattcat gattccagga ctagctttaa caagcctatc tctgactttt atcctagcca
    14521 ctcgtctccc actactagaa agctggtttc acggtttgga gaaggtctac accgtccaca
    14581 aattcacagc ctttctctcc atcatcctac taatctttca taactttagt atgggcggtt
    14641 tgtggggctc tcgcttagct gctcagtttg gcaatcttgc catctatatc tttgccagca
    14701 tcatccttgt cgcctattta ggcaaataca tccaatacga agcttggcga tggattcacc
    14761 gcctggttta cctagcctat attttaggac tctttcacat ctacatgata atgggcaatc
    14821 gtctccttac atttaatctt ctaagttttc ttgttggtag ctatgccctt ttaggcttac
    14881 tagctggttt ttatatcatt tttctatatc aaaagatttc cttcccctat ctaggaaaaa
    14941 ttacccatct caaacgctta aatcacgata ctagagaaat tcaaatccat cttagcagac
    15001 ctttcaacta tcaatcagga caatttgcct ttctaaagat tttccaagaa ggctttgaaa
    15061 gtgctccgca tcccttttct atctcaggag gtcatggtca aactctttac tttactatta
    15121 aaaattcagg cgaccatacc aagaatatct atgataatct tcaagccggc agcaaagtaa
    15181 ccctagacag agcttacgga cacatgatca tagaagaagg acgagaaaat caggtttgga
    15241 ttgctggagg tattgggatc acccccttca tctcttacat ccgtgaacat cctattttag
    15301 ataaacaggt tcacttctac tatagcttcc gtggagatga aaatgcagtc tacctagatt
    15361 tactccgtaa ctatgctcag aaaaatccta attttgaact ccatctaatc gacagtacga
    15421 aagacggcta tcttaatttt gaacaaaaag aagtgcccga acatgcaacc gtctatatgt
    15481 gtggtcctat ttctatgatg aaggcacttg ccaaacagat taagaaacaa aatccaaaaa
    15541 cagagcttat ttacgaagga ttcaagttca aataagtaat catactctcc tgggatttcc
    15601 caggagagtt ttttatagcc aaatgaaata agacaggaac gatggaattt tggcattcaa
    15661 atcaattgat aagaatgttt tatagtggag tgaaatagga tacgaacaaa ttgattagga
    15721 aaatcaaatg aatttataga aatcttttag cagttatgtt gtcctattct agtttcaaaa
    15781 cgctatagaa gcagcattgt gctagtctag attcagttta ctatactaaa acgagtagct
    15841 tgaaatcaaa aaacccaccc tcacaggcag gttttatctg tattattcag ctagattatg
    15901 ctttaccttc tgaaccgaat acgtcgatac gttcttcaac cgatgcttgg atagctttta
    15961 caccgtcagc caagaattta cgtgggtcga agagtttttt cttgtcgtat tctgcttcgt
    16021 ttgcttcgta gtcacgagca aatttacgag ttgcgttagc gaatgcgatt tggcattctg
    16081 tgttaacgtt aactttggca acaccaagtt tgatagctgc ttggatttgc tcatcaggaa
    16141 tacctgatcc accgtgcaat acgattggga atcctggaag agcttctgtc aatttttgca
    16201 agtggtcaag gtcaagacct tcccagttta ctgggtaagg accgtggatg ttaccgatac
    16261 cagctgccaa gaagtcgata ccagtttcaa ccattgcttt agcgtcttcg attggagcca
    16321 attcaccttt accgatgatt ccgtcttctt caccaccgat agtaccaact tcagcttcta
    16381 ctgagatacc tttagcgtgt gctttttcaa caacttcttt agccaattta aggttttctt
    16441 caactggaag gtgtgaaccg tcaaacatga ttgaagtata accaacttcg atacactcaa
    16501 gtgcatcttc gtagtgaccg tggtcaaggt ggatagctac tggtacagtg atacccattg
    16561 attcaacaag gttagcgatc aagttgcgag caactttgta accacccatg tatttagcag
    16621 cacccattga agtttggatc aaaactggag cttttttagc ttctgctgcg cgcaagatag
    16681 cttgagtcca ctcaaggttg tttgtgttaa atccaccaac tgcataaccg ttgtcacggg
    16741 ctgcttggac aaatttttct gctgaaacga ttgccatttt atcaggcctc ctgtatattt
    16801 ttatgggtca tcccatttac attgttcatt ttatcacttt ttgccaaaaa aatctagttt
    16861 ttcccgcagt ttcgattgat tttcttctaa ctccatctat gtaaaccctt tctctcccta
    16921 gtcttggacg acttttggaa aatctataaa gaaggttaaa cgattctcct ccatctcgaa
    16981 acgataagct aatttttcat gttctaatag actcttaacc acaaagagcc ccataccaga
    17041 ccccttgacc ttgcgactgg cattgtcaga aaaagactgg gctagttttt cttgttcctc
    17101 tgagctacag ctattttcga taaaaagttc tccttctctt tctccaattc gaactaagcc
    17161 acctggaaca gagtgcttaa tggcattgct gatgagatta gaaagaatca acttcataac
    17221 tgatgggttt agataagcct gctgatgggt caaactattg tctatctgga gctctctttc
    17281 cttggctagc aaggcataat ctttgaccag attttgcgtc atctggagga ggtcaattgt
    17341 ttccctatca tctcgcaatt cctgcacaga agagagggaa agtatctgca gaacatggtg
    17401 attgagttca tccacaatcc ccaaggcaac tcccagatac tggtctctat ccttataacg
    17461 accgatattc tctctcatat tttcgattag gattttcaaa ctagccagcg gtgttttcaa
    17521 ttcatgagaa gctcctcgta ggaattcgac cttcatcttc tccagctgga gaatggcttc
    17581 attcttttca tgcaagtccg caataacagt caagagatgc tggtagaggc tattgatttg
    17641 ttccttgaga ttacctatct catccttaga atccacgcgc aatcgcactt gggcatccag
    17701 gtacatcatc cgacgagtca cccgcttgat ttccaaaatc ggtgcaacaa tagtccgagc
    17761 gtagatgtag gccaccaaga gggaaatcag aaaggaggcc agcaaggtat agggaagaaa
    17821 ctggagactg atttgctccg cttccttttg taaatccatg gaagctagaa actggagaat
    17881 catagtacca ccgtcttgcg ttttcacctc gcgctcctca ataaagagag aggttgtctg
    17941 gcggtctgtg tccagaggaa gactgtcctt gacttctaac ttgtcctcgg tcatctcacc
    18001 tttgacggtc cccttgatat cactagtctg ggaatacaag tctaacactt gctcgatact
    18061 ctgcctatct ttcccttcta gggactgggc aatggctgtt gccttttgac caatggtttc
    18121 ctgacgatga ctcagataag tcgaaggaaa aagaaaataa atagctaaat gaaggcagat
    18181 aaccagaaca ctaaatatcg agaaggtata gataaatatc tttgcaaata aacctgttcg
    18241 tttcattttc gctccaattt ataaccaaca ttgcgcacag tgaggataca atccaagtct
    18301 agctttttcc gcaattcctt gatataaaca tcaataacac ggtcaaaggg aacctcatct
    18361 gtcgctttcc agacggcatc gataatctga gaccgagtca aggcccggcc ttcatttttc
    18421 actagatagt ccagaatttc caactctttg gcattgatag gcacttcttg acctgcgagg
    18481 cttgcactgt agctttcaaa gtccaccttg gtatccttgt aagaaaagat tcgtcctgta
    18541 tcgtagtagc gcttgaaaat cgcgtccacc ctcactttta agagggagag agagaaaggt
    18601 ttttccagat agccatctgc caaagaggca aaggcactca tcttgtattc ctcatcctga
    18661 aaagctgtca acatcaagac aggaacctga ctggttttac gaatctcagc taggacttct
    18721 aagccgttaa gcttgggcat ctggatatcc agtaaaacca gggccacctc atagctagaa
    18781 aattgctcca gagcttcctg accgtccgct gcctcaatag tttcatagcc acaatccgtc
    18841 aaataatcac tgaccccctc acggatcatc tcttcatctt ctacaattaa aattttcata
    18901 ctttaactgc tctctatttt ttatttttct tagaataaat acctactcta ttttctatta
    18961 tagtctcttg ctggcctttt gtctgtaagt aactgaccac tagataaaac gttgtgaaat
    19021 tcctttctca taaattccat aactttagta tattatattt aagcactaaa gtacaaagaa
    19081 agcaactgaa agcaatgatt ttcaccactg ctttcagatt tattttgaat tgttaaatag
    19141 ccattcctat ccactattct tgaatagaaa cacaagatgc aatctttatt ccagactcat
    19201 tttttcaaat ttattcacca tccagcaaga gttcttttgg ttgttttcta aggagattgc
    19261 ttgaagcaag cgccataacg agaaccacta gaaccaaggc aaggacaaaa atgatgataa
    19321 agtctgatgt ctgaatggaa atgtctaggc tcgacaaggt cttgctaaag ccatctactt
    19381 ctgcaccacc accaaggtta gaggcttgag ccgccttact agcctgtttg gcaacacctg
    19441 aagtcacatt ggcaaggaca gtgtttccaa ttgcacgggc agtgtaatta gctaggaagt
    19501 aagcagaaac tagagcaggg atagcaatca agatagattc ggtgatgaat tgacccaaga
    19561 tacttgcctg cttgaggccg atagagagga gaattcccac ttccttgcga cgggcgttga
    19621 tccaaaggct gagcaagagg gcaaggagga gaactgagaa gctcaagcta ccccagaaga
    19681 ggaggttggc catcttgtac ataccagaga tagattgctc aagagctggg tagttagagg
    19741 agctcttgac gagtgtgtag ctcttccagt tgataccact gatgccattc aactctttca
    19801 taacatcatc caagttcttg tctgctgtta caaagaaggt tgcgtcccca taaatggctg
    19861 tgtcttctgt gtatccataa agttttgcag cagtgtgaat gtctgtaata gctgtgtttt
    19921 cgtaaagttc ttgtgagtag gttactgctg acttattatg accatcaaag agtcccttga
    19981 ttgtcacttc aactgtttcc ttggctcctt tttcattatc tgcatcgtag atattagagt
    20041 ccagtttaac cttgtcccct actttccagc cgtgtttggc tgccaagtcc ttgtgcaaga
    20101 ggattttatc cttgtcgtcg ttggttaagt gctctccttc gactagttta taagaaccag
    20161 agacaaactt gtcttcttta gaggagtcat tgacacctgt aatcatcaag ctacttccaa
    20221 aacgtttggc acgatcagca gtgagattct tcttggtttc tggcgtttca atcaggtcat
    20281 atccagtcaa atctccgata gcgttgatac gtttgacata agactcgatg gccttgtttt
    20341 cggtgatttt tttgatgtct tcacccttga tattcccagc accacgaggc gttccttggt
    20401 tgacgcgacg attgatttgc atggagaagc tattggtgat atttttaaag gtctcctgag
    20461 aagccttggc agtagctccc ttgattgaca agccgaccaa actcaagctc gccatgagga
    20521 gaataatcag gaaaatgaca atcgatttga aaaacttcct tgtaacatag gcaaatgcgt
    20581 tgtgtaacat agattccctt tctagatttt gttttaatca ttctatcaaa ataagctcaa
    20641 attatttact agtattgcgc gtttcagtca gtttcttatc ctttaattca agtgtaatat
    20701 ctgacgcttg tgccacttct ttactgtgag ttacgacaat cacacattta cctgttttct
    20761 gggcaagtga tttgagtagt tcgacaatat ctccagcagt tttaggatcc agatttcctg
    20821 ttggctcatc agctagaata actggagctt ctgagaccaa actgcgagca atggcaacac
    20881 gttgctgttg accacctgat aactggagaa cattccgctt gatctggctt tcatccaaac
    20941 caagctcaag aagtgtattc ttgcttgcct ttttgttgac caatcggata ttttccagcg
    21001 gagaaagata atctatcaag ttataatttt gaaagaccag ggaaatatgg tgcatgcgat
    21061 ggtaagaata gcccttctta cgaatatcct ctccttgaaa aaggatagaa ccttcaacag
    21121 gactatctag accagcaagt agggacaaga gtgtggattt tcctgctcct gactccccaa
    21181 taatactgta aaattttcca ggttcaaaat tataatcgat ctgatatagg actgcttcag
    21241 cagtattctt ataacggtag gtaacatctt gtaattgtaa taaagtcatg atttctcctt
    21301 cttaactaat agatgataaa atttctttcg gtgattttct aaataagaat aggaaacaaa
    21361 gggctacaga taagcaacta agcagaacta gaaaaacata ggattctgca aaagataaga
    21421 tgctagttga taaactgctt gctttggcta gtgtatcttg taagcttgcc tgatctccac
    21481 ttgctagtag agtttggagt aggtaagttg tgattccgtt tcctgcaaca aatgctggaa
    21541 gcaaagctcc aagagatacc aaaactacct ctaaacagaa ttgtaggaag atcgagctct
    21601 tgccttttcc aagtgcaagt aaaatcccca cttcatagac ccgttctctc aaccagagag
    21661 acaaaaccag aattaaggct ccagctcctg ctatcaacat cccataaagg aagatggtca
    21721 ggaaggtttg gaaagttgca actgagtctt tgatttgttc aaaagccttg ttttcctttt
    21781 cgacttggta gccttgattt tccaaggcca agttttctac ctgcttcatg agtccgtcca
    21841 tttccttagg attttctaca tagaagcgtg ctgcactgac ttgagcttca ctattgccca
    21901 aaagggtttg gctactttca tagtctgtaa agacttgatt ttcactgaag tcagaagaca
    21961 agcctgtgaa tttctcttgt tttttaccag aaaagatgcc aataatctca aactctactg
    22021 tttgtccttt tccagattca gactgaccag catccaagcc aatcttgtca tgaagtgaaa
    22081 gaccgttctt cttagccaat tcttcgtgga taaggatttt cttggaatcc cctttttgaa
    22141 ggtgtcgccc ttcttttaga ttgaaagccg aactggtaaa ggttacatcc ttggatgaat
    22201 cctcaagagc cgttaagcta accaagttat tgtctgcagc tgataaatca tcacgctcca
    22261 cgctctgctc tccagtcact gcttccttgt cttttagttt tgcgaccgtc tcaagttcag
    22321 gagagacatt ttccagcccc ttaatcttgc ttacagatgc taggtctgac aacttgaatg
    22381 tctgaccatt ctctatcttc ttaatagaaa aagatgtatt gagtgattta taaagattgc
    22441 tttctactgt tttgttggac ttcatcagag tcaaacaggc tgaaattccg gccaataaga
    22501 ccaataaaat cagaaataaa ataaaacttc tcagtcgctt tctgctgaca taagcccaag
    22561 atctttggat tggattcatt tgtcacctcc atatttgtaa gactattata aaacccaaat
    22621 atgaaatgtt tatgaaatac gaaaaaaaaa tatcgagtag gggataatct ctagcccctc
    22681 tcacaccacc gtacgtgccg ttcggcatac ggctgttcaa ctaactttta acgcatg
//
LOCUS       DAVMCN010000025        22461 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVMCN010000025 DAVMCN010000000
VERSION     DAVMCN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.025"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(195..392)
                     /gene="blpI"
                     /locus_tag="VYP85_001192"
     CDS             complement(195..392)
                     /gene="blpI"
                     /locus_tag="VYP85_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1881716.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            682..1269
                     /locus_tag="VYP85_001193"
     CDS             682..1269
                     /locus_tag="VYP85_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1881717.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1196..2839
                     /locus_tag="VYP85_001194"
     CDS             1196..2839
                     /locus_tag="VYP85_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1881718.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2850..4211
                     /locus_tag="VYP85_001195"
                     /pseudo
     CDS             2850..4211
                     /locus_tag="VYP85_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            4268..4423
                     /gene="blpC"
                     /locus_tag="VYP85_001196"
     CDS             4268..4423
                     /gene="blpC"
                     /locus_tag="VYP85_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1881719.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(4465..5805)
                     /locus_tag="VYP85_001197"
     CDS             complement(4465..5805)
                     /locus_tag="VYP85_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1881720.1"
                     /translation="MNIAWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(5819..6556)
                     /locus_tag="VYP85_001198"
     CDS             complement(5819..6556)
                     /locus_tag="VYP85_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881721.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFEYRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6561..6899)
                     /locus_tag="VYP85_001199"
     CDS             complement(6561..6899)
                     /locus_tag="VYP85_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881722.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7175..7504
                     /locus_tag="VYP85_001200"
     CDS             7175..7504
                     /locus_tag="VYP85_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1881723.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLDSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLSL
                     YGPTIIL"
     gene            complement(7565..8614)
                     /locus_tag="VYP85_001201"
     CDS             complement(7565..8614)
                     /locus_tag="VYP85_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881724.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPTLLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLVMGYGLPVFLVYVLLLGVGKYFLFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKVVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQSWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLISFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8611..9342)
                     /locus_tag="VYP85_001202"
     CDS             complement(8611..9342)
                     /locus_tag="VYP85_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881725.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9410..9820
                     /locus_tag="VYP85_001203"
     CDS             9410..9820
                     /locus_tag="VYP85_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1881726.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9830..10117
                     /locus_tag="VYP85_001204"
     CDS             9830..10117
                     /locus_tag="VYP85_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881727.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10279..10518
                     /locus_tag="VYP85_001205"
     CDS             10279..10518
                     /locus_tag="VYP85_001205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881728.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10840..11976)
                     /gene="dnaJ"
                     /locus_tag="VYP85_001206"
     CDS             complement(10840..11976)
                     /gene="dnaJ"
                     /locus_tag="VYP85_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1881729.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12378..12734)
                     /locus_tag="VYP85_001207"
     CDS             complement(12378..12734)
                     /locus_tag="VYP85_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1881730.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12736..14559)
                     /gene="dnaK"
                     /locus_tag="VYP85_001208"
     CDS             complement(12736..14559)
                     /gene="dnaK"
                     /locus_tag="VYP85_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1881731.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15039..15563)
                     /gene="grpE"
                     /locus_tag="VYP85_001209"
     CDS             complement(15039..15563)
                     /gene="grpE"
                     /locus_tag="VYP85_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1881732.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15590..16624)
                     /gene="hrcA"
                     /locus_tag="VYP85_001210"
     CDS             complement(15590..16624)
                     /gene="hrcA"
                     /locus_tag="VYP85_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1881733.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16788..17298)
                     /locus_tag="VYP85_001211"
                     /pseudo
     CDS             complement(16788..17298)
                     /locus_tag="VYP85_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            17906..20239
                     /locus_tag="VYP85_001212"
     CDS             17906..20239
                     /locus_tag="VYP85_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1881734.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKAHRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20252..21715
                     /locus_tag="VYP85_001213"
     CDS             20252..21715
                     /locus_tag="VYP85_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1881735.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINAIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21715..>22461
                     /locus_tag="VYP85_001214"
     CDS             21715..>22461
                     /locus_tag="VYP85_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1881736.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIVEAIESA"
BASE COUNT         7156 a         4530 c         4125 g         6650 t
ORIGIN      
        1 agttaagttt tttattccta ccaatccatc aactaagtaa agcatcaacg attacataaa
       61 cgattgataa tataattaaa attttgctaa ctatcttatt ctcatcattc ttagataact
      121 ttgatatttt gtaagtaagt aaataagaca gtaaattaat agcgataata atactatatt
      181 taagaatcat aatcttacaa agaggacata attcctgaac ctacacaaat aagtgttgct
      241 gctcccccag ttatcggacc agtcgcagca gctaatagta ctgctccaat acaaccaccg
      301 attgcagatc ctaaattgcc tcttcctcca ctaactattt cgagttcttc attatccata
      361 acagaaaatt gttccatcat ttttgtattc atgacaaata ctcctttttt atttttgtct
      421 tgttgtaact ttgataagtt tagtatatca tcgtttttta aaatttttca tccagatctt
      481 gaattgtcat cgaaacgtct tgaattagct tttttatttc aagccacctc tatttcaagc
      541 cacctctaaa tgtttaaaaa aaataatttc taatcacttt tttaccattc aggaagtttt
      601 aatgactatt caagatttca taaaatatga acttagtttt atgacataat agacctatcc
      661 actatatgaa aggaattgcc aatgacttct tataaacgta catttgttcc tcaaatagat
      721 gcgagagact gtggtgtcgc tgccttagcc tcgattgcta aattctatgg ttcagatttt
      781 tctctagctc acttgagaga acttgcaaag accaataaag aagggacgac tgctcttggc
      841 attgtaaaag ccgctgatga aatgggcttt gaaacaagac ctgttcaagc agataaaacg
      901 ctctttgaca tgagtgatgt cccctatcca tttatcgttc acgttaacaa agaaggaaaa
      961 ctccaacatt actatgttgt ctatcaaaca aagaaagact atctgattat tggtgatcct
     1021 gacccttctg taaaaatcac taaaatgtca aaagaacgct ttttctatga atggactgga
     1081 gtagctattt ttctagctac caaacccagc tatcaacccc ataaagataa aaagaatggt
     1141 ctactaagca agcttccttc ctctgatttt caaacaaaaa tctctcattg cttacattgt
     1201 tctctcaagc ttattggtca ctattatcaa tataggtggt tcttactatc tccaaggaat
     1261 cttggatgaa tacattccaa atcagatgaa atcaacttta ggaatcatct cagttggtct
     1321 ggttatcacc tatatcctcc aacaagtcat gagcttctcc agagattatc tcctaaccgt
     1381 tctgagccag agattaagca ttgatgtgat tttatcctat attcgccata tttttgaact
     1441 tcccatgtct ttctttgcga cacgtcgtac aggagaaatc atttcacggt tcacagatgc
     1501 taactctatt atagatgtct tggcttctac cattctttct ctttttctgg atgtttctat
     1561 tctgattctt gtagggggag tcttgctggc acaaaaccct aatctcttcc tcctttctct
     1621 tctttccatt cctatataca tgttcatcat cttttctttt atgaaacctt ttgaaaaaat
     1681 gaaccatgat gtcatgcaaa gtaattctat ggttagctct gccattatcg aagatatcaa
     1741 cgggattgaa actataaagt cgctcacgag tgaagaaaat cgctatcaaa atatagacag
     1801 cgaatttgta gattatttgg aaaaatcctt taagctcagt aaatattcta ttttacaaac
     1861 gagtttaaag cagggaacaa aattagttct gaatatcctt atcctatggt ttggcgctca
     1921 attagtcatg tcgagtaaaa tttctatcgg tcagctgatt acctttaaca cacttttttc
     1981 ttactttaca actcctatgg aaaatattat caacctccaa accaaactcc aatctgcgaa
     2041 ggtcgctaat aaccgtttga acgaagtcta tctagtcgaa tctgaatttc aagttcaaga
     2101 aaaccctgtt cattcacatt ttttgatggg cgatattgaa tttgatgacc tttcttataa
     2161 gtatggtttt ggacgagata ccttaacaga tattaatctc acgattaaac aaggagataa
     2221 ggttagccta gttggagtta gtggttctgg taaaacaact ttagccaaaa tgattgtcaa
     2281 tttctttaaa ccctacaaag ggcatatttc catcaatcat caggatatta aaaacattga
     2341 taaaaaagtc ttgcgccgtc atattaatta cctaccccaa caagcctata tctttaatgg
     2401 ctctattttg gaaaacttaa ccttgggcgg taatcatatg attagccaag aagatattct
     2461 aaaagcttat gaattagctg aaattcgtca agacattgaa agaatgccta tgggctatca
     2521 aactcagctc tctgatggag ctggtctatc aggaggacaa aagcaacgaa tcgctctcgc
     2581 tcgtgctctt ttaactaaag ctcctgtttt aatactagat gaagctacta gcggtcttga
     2641 tgtcttgact gagaaaaagg ttatagataa tcttatatcc ctaactgata aaaccattct
     2701 ctttgtagcc catcgtctca gtatagccga acgaaccaac cgtgtcattg ttcttgacca
     2761 ggggaaaatc attgaagttg gtagtcacca agagttaatg caggcgcaag gcttctacca
     2821 tcatctattc aataaataag gagaatgtca tgaatcctaa tctttttaga agcgtcgagt
     2881 tttatcagag acgttaccat aactatgcga cagtattaat catacctctg tcattactgt
     2941 ttactttcat cttgattttc tcccttgttg ccacaaaaga aattactgtt acttcccaag
     3001 gggaaatcgc ccctacaagt gtcattgcat ctattcagtc gaccagtgat aatcctatcc
     3061 ttgctaatca tttagtggca aatcaagtag ttgagaaagg tgacttactc atcaaatact
     3121 ctgaaacaat ggaagagagt cagaaaactg ccttagaaac tcaattacaa agatttgaga
     3181 agtaaaaaga aggacttgga attttgaaac aaagcttaga aaaagcgact gatctttttt
     3241 ctggcgagga tgaatttggc taccataata cctttatgaa ttttactaaa caatcccatg
     3301 atattgaact gggtatcaca aagactaaca ctgaggtttc aaatcaagct aatcttgcca
     3361 atagcagttc atcagctatt gaacaagaaa ttacaaaagt tcaacaacaa attggagaat
     3421 atcaagagct gagagatgct atcataaata acagagcacg cttaccaact ggcaatccgc
     3481 accagtcaat tttaaatcgt tatcttatag cctctcaaga acaaacacaa ggaacggcag
     3541 aggagccatt tttatctcaa attaatcaaa gtattgcagg tctggaatca tctatcgcaa
     3601 gcctcaaaat tcagcaagct ggtatcggaa gtgtagcaac ttatgataat agtttagcaa
     3661 ccaaaattga agtactccgc actcagtttt tacaaacagc ctcacagcaa caactaaccg
     3721 tggagaatca attaacagaa ttaaaagtac aactagatca agcaacgcag cgcttaggaa
     3781 acaatacctt aaccgctcca agtaaaggta tcgttcatct gaacagcgaa tttgaaggta
     3841 aaaatagaat tccaactggt acagaaattg ctcaaatatt ccctgtcatc acagatacaa
     3901 gagaagtact aatcacttac tacgtatctt ctgactatct acctctacta gataaaggac
     3961 aaactgtaag attaaaactg gagaagattg gaaatcacgg caccaccatc atcggccaac
     4021 ttcagacaat tgatcaaact cctaccagaa cagagcaagg caatctcttt aaattaaccg
     4081 ctcttgcaaa actatctaat gaggatagta aactcatcca atatggctta caaggtcgcg
     4141 tcactagtgt aactgcaaag aaaacatatt ttgattattt caaagataaa attttaaccc
     4201 attctgatta attttcagat aacactctat aactatttat tatcttatca aaaaggagaa
     4261 tcataacatg gataagaaac aaaacctaac ttcatttcaa gaactaacaa ctaccgaact
     4321 caaccaaatt acaggtggag gatggtggga agaactctta catgaaacaa ttttaagtaa
     4381 atttaaaatc acaaaagcac ttgaactacc tattcagcta taaaaacaag accgagaaac
     4441 aagaactctc ggtcttgttt tttatcattc tgcatgtatc acagtaagta cctgacgaaa
     4501 gacttgattt tggcaggtag tatttagatt ggtattggga tgactttcca caatcttcat
     4561 aacggtatag agaccaactc ctctctcctc ccctttagaa ctggctccaa aggagaagat
     4621 ttcagaaata tcgatgccct cttctttgat ggagttttca atgataaaag tctcctgtgc
     4681 tccatttttt aaaaaggcga ttgaaacatg aggttgactg gcctctgcac tagcttcaat
     4741 agcattgtca caaaggatag acacaatggt tagaaaatca agtaggctca tcccctcaac
     4801 ctgaatctcc tcaggaactt caacattaaa gacaatgttc ttttctctag cttttataaa
     4861 ttttccagct aggagactct tgagggcacg gtcacgaata ttcaccaatc tgcccaggtc
     4921 atatttattg tcctgcaatt tctgactgga atcccttaag accgagtcgt agatctcttt
     4981 tatctgctcc atatcctcct cttcaatgcc caaacgtaag ctggttaaga ggttagtgta
     5041 gtcatggcga aaactccgaa tttccttgta aagttcctct atatgccgac tatagcgttc
     5101 catatctctg tagcgcaagg tctgctcttg gttcagttcc tcctgaagtt tttccttcaa
     5161 ataggtatcc aatttcttga taccccccat aaaaaagagt aggtaaaaca ctaggatgag
     5221 atggcgaaca gtcgttgatt gaataccttg ttcatattca aggtaagata gactttgcat
     5281 cactagataa taagccccca ttgcccagtt aatcttagta agagactttt gaaaacctgt
     5341 atctagaaac tcccttctca atctagtgaa atcatagtct aaccatttca aaaagactaa
     5401 aactatgaag caaacgaata tcataatcaa taaaaagata ggattgccat ccccatctac
     5461 aattccttgc cccaaaaatg gaagcacaaa ataggaaaca cctctgtaaa agagctctac
     5521 taatatcatt gggaagagac cataaaaaat aaggattttt ttaggaagcc ctcttaacaa
     5581 taagaaagat agacctatac cgaacaaagg ttctataaaa taggacaaat atttacttac
     5641 agccaaaaat tgaaaagtcg taaaaatgat ccctagaaga aatttcagaa gaaaggcctt
     5701 aaaaattcta tcgaaagtga gaccaattcc atctacttta aagaaaatga caatttctag
     5761 tccattaata acaagtgcat acaacaatat ccaagcaatg ttcataaact ctcctagctc
     5821 agtgtaagtt attaatagcc tcagacactt ccctgacctt ataacgcgcg atcagacaac
     5881 ttccaccatt gggaaagaaa aggagttttt ctttcttatc caaatgcacc acatttgcag
     5941 gattgatgag aaaagagcga tggcactgca agagacgggg ttcctgcttg aaaacctcct
     6001 ctaaactcgc tgtaaattcc agcctgtctg tcttggtata gagaataaca cgatggggtc
     6061 ttggggatgt ttcgagatag taaacctctt taaaaggata ctgaaattgg gcaaattttg
     6121 atttaaagta aaagcaatct tccgccagac ttttactatc ttgactattg gcatagagga
     6181 gagctgtctc gattcgatat tcaaactcct ctgccgaaag ggccttatca atatagtcca
     6241 gagcagacac ttggtagcga aaggacaggg gcataaactc cgagtgagtc gtcacaaaga
     6301 caatcagggc ataggggtct tgttcccgaa tctttctagc cacttccagc cccttcatct
     6361 cctcatttcg aatctcaata tccaaaaaga atagctgatg ggcccccttc tcatgcacct
     6421 ctgccagcag ttggtctggc ttgccaaata cctcaaaaga gctgggagtg atatgatgtt
     6481 ccttcaagag tttctcaatc gtcgtttcaa tcctagtctg ttgggaaaaa tcatcctcta
     6541 aaacaaatat tctcatcttt ttactctccc tctttcaacc atttttgacg tatttctcta
     6601 tagcgacgtc tggcatactt gacagcgtat tgaccttctt ctccgagaaa aaggattctt
     6661 tcttgaaaat caatcgattt taatttatca agattaacca aacaatttcg atgacatctc
     6721 atcaaagttt ccccacattg gttctcaaga ttacttaaat tttgaagcat attaaaacta
     6781 gctttttctg taacaatctg tacggtatgg gctttagttg gatgtgtttg gatatagtag
     6841 atatcgtcga tgtttacttt atagactgtt ttctgtgtct gaataatcat atgtttcatt
     6901 ggattctcct cctaagaaaa gaataacaga aaaggtctag cccaagcaca cccaatccta
     6961 aacagtcttt gaaaactcct aaaaggatta ttttctacaa catcatgatg agcttacaac
     7021 tattttatca taaaattcac tcagcgcaat tcaagacatt tcaatgacaa ttaaagattt
     7081 gaataaaaaa aaagaattaa aagtgataaa ctaacagtat caaaacacag ttgccagaag
     7141 taagactggc acccagatta aaggaggcat tcccatgaca gatacagacc ccatcaaaag
     7201 agctcacact ttgattactg acttaaacaa agcctaccaa gcatgcaaac aggcaagcgc
     7261 tgacgacgtc cgctttcaag agcaattaga ctctattctt ggttttctag ccaaggctga
     7321 gacagtggat aatcgattct tgattgaact ggaaaaattt taccagactt ccagtcttct
     7381 catgggactc agcgctcttg atccagatgc tccaactcgc gctgcttggc gagcctatga
     7441 ccgcttccac tttgaccaag tcaagaccaa gttgagtctc tacggaccaa ccattatctt
     7501 gtagaaaata aaagaagttg agacaaactg aactcaactt cttttttagt gtcatataag
     7561 catcttagtc ctgcatctga cgttttacct gataaggtag gtacaagact agtaaaacca
     7621 aaccagctcc tagtaaggct agaagggcta gtttttcttg gaaggtaatc aacccaacaa
     7681 ctaattccac aagtaaaaca aaactgatca atcctcgaac tacctcctgt aagccttttt
     7741 ccttttgccc cttgtccagc ggaaagagtt gggtcaaata ctggtagtca aaggcatgat
     7801 agagggccag caactggaaa agcaagaggt agttaaagag aactaccact gctgtcgcaa
     7861 tccaagattg ctcgataaag acctgcgcca gcaaagaaag caagagcaga cggagactaa
     7921 gggcaaaaag gtctccattt cgcaaataag aacgcagata gagattttgc caaatcttcc
     7981 cagacacctt ctgaacaacc tttagaataa agtccagata ggcacgacgc ttgacgctgt
     8041 ttgaaattcc cttgacctgc gtaaagaggg caaagaaacg aagcaagact tgcttacgct
     8101 tgctttcttg ggaaatgaca tagtcccaat ccagtccagt ttcagtgaaa aatttgctgg
     8161 ccttttgacg aaagaggaaa tattttccta cccccaataa aagcacatag accagaaaaa
     8221 caggcaagcc ataacccatg actaaaaaca agggcgcaaa taacagcaag aagagggtct
     8281 gaacaaaaat ccaaaagact agggaaatgc cggtttgacg cttgagatgg agcttgattt
     8341 cctcttctcc aactaagaga aagagcttgt ctggagcctc catataggtg gcaattcctc
     8401 cccaaagtaa aagtaaaaca gacgtaattc ctacaaacaa aagggtaggc caatgatttt
     8461 caggaaaatg ttgtaagagt tgactgtact ggtaggctag aaagcccaac aggacaagca
     8521 ggaacaagac aaagtggtca ttgagcacat agcgcagata acaaagacac tccttacgaa
     8581 aggcctgctt tctctttaaa aacaagtctt tcatagatcc tcctctttgg tcagagccaa
     8641 gtaaatatca ttcaaactag cctcaggcat atcaaaggct tcacgtagtt gcaggagatt
     8701 gcctttggca cgcacctctc ccttgtgaag aatgacaaag gcatcacaca tcttctccgc
     8761 cgaatccagc acgtgggtac tcatgagaat agacttgccc ttttgcttct ccacttccaa
     8821 aagctgaatc aaatcagaaa tagccagcgg atcaagacca aggaaaggct catccacgat
     8881 gaaaaggctt ggatccacca caaaagcaca gataatcatg accttctgct tcatcccttt
     8941 tgaaaaatga acagggaacc agtctaattt ctggtccaga cggaacatct ttaacaaggg
     9001 ctctactcgt tcgaaagcca ctttttgctc aataccgtaa gccatagcaa ccgtttcgat
     9061 atgctctctg agggtcaatt cctcatacag actaggcgtc tcaggaatgt agccaatctg
     9121 cttgcggtag ctagtcgcat ctccttgcag agtcaggcca ttgatattga tggagccact
     9181 ataaggtgcc aacagaccga taatctcatt gatcgtcgtt gatttcccag caccattgag
     9241 accaatcaaa ccgaccaact gcccactttc aacagtaaag gacacatctt tcaaaacagg
     9301 aacatgaaca tagccacctg tcaggttttt aatttctaac atattttctc caaatctggt
     9361 ataatgtagc tatattatat caaaatttag tacagtagag gtagatttta tgtcagattg
     9421 cattttttgt aaaatcatcg caggggaaat tcctgcttca aaagtatatg aagatgagca
     9481 ggtccttgcc tttcttgata tctctcaagt aacactagga cacaccttgg tcgtgccaaa
     9541 agaacactat cgcaatcttt tggagatgga tgctacgagc gccagccaac tctttgccca
     9601 agtaccaaaa gtagctcaaa aagtcatgaa agtcactaag gctgctggta tgaatatcat
     9661 ttccaactgt gaagaagtcg ctggtcaaac agtttttcat actcacgttc accttgtgcc
     9721 tcgctacagt gctgacgatg acctcaagat tgattttatc gcccacgaac cagactttga
     9781 caaacttgct caagtcgctg aaaccatcaa aaacgcttaa ggagttgcta tgaaattatc
     9841 caacctactg ctatttgcag gagctgcagc cggaagttat ctggttacaa aaaatcgcca
     9901 aaccatcaca gatgaagtct tgaataccac tgaccgcgtt caagctatca aggacgatgt
     9961 ggatattatc caaaacagcc tgcaaatcat taaccagcaa aaagaactta tcaaggaata
    10021 ccaagaagac ttgacttaca agtttaaggt cttggaaaag gatatccaga ctagactagc
    10081 tgtgataaaa gaaatgcagg gaactgaaga taagtaaaaa gagccccccg gctctttttt
    10141 aaaacgtaaa caagttatag tgaattgaat ttagaatagc acaccatagt ttctaaagca
    10201 ttgttagaga ttactttaaa atcctcttat caatttgttc atattctatt tcaatctatt
    10261 atatatatcc catcaactat gcatcataat ttaggtaact catactcaat aaaaatcaaa
    10321 aagcaaacta gaaagctagg cacagactgc tcaaaacacc gttttaaggt tgtggataga
    10381 actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt
    10441 aaccataccc atggcaagcc gacgctgacg tggtttgaag aaatttttga agagtatcat
    10501 tcaccatttc acaactaaat cgaagacttt ctgccgtaat gaaaacacct gaaacagctt
    10561 ggtttcagct gtccggaaac tttaagactt aggttcaaag tttaggtatg gaacttcgaa
    10621 ggaggtcgct accgtccgtc attacttagg aaagtcttaa aaaatctata aagtaaaaag
    10681 agcccgacag ctctttttgt ttatactcaa tgaaaatcaa aaagcaaact aggaaactag
    10741 ccacgggctg ctcaaaacac tgttttgagg ttgtagatac gactcacata tatacggcaa
    10801 gccgacgctg acgtggtttg aagagatttt caaagagtat tattctccat caaaggcatc
    10861 tttaatatga tcaaagaagc cttttttctt tggatttact ttcaagtcac cagcagccgc
    10921 gaattctttc aaggctactt tttggcggtc gttcaagcct gtcggtgtta cgacattaac
    10981 agtaacgtat tggtcaccaa ctgcaccgcc acgaaggctc ggtgccccct tactacgtag
    11041 gcggaatttc ttaccagtct gagttccctc tggaataacc aattcaacat caccgtgaac
    11101 agttggaata tctactgtat caccaagagc cgcttggaca aagttgaggt tgagattgta
    11161 gaagatagtc gttccttcac gttcaaactt gtcgctagct tccacagaaa ctactacata
    11221 caagtcacca taaggtccac cgttaaagcc tgcttcacct tgaccagcga ggcgaatttg
    11281 ttgacctgtt tccacaccag cagggatttt cacatgtacg ctatgagctt gtttctcatg
    11341 acctgttcca tgacaggttg tacatggata tttgatttct tttccttggc cgtgacagac
    11401 atcacaggtt acttggcgac gcatcatacc aagaggagtc tgcgtatcga cgttaatgac
    11461 accagcgcca tgacagcgtc cacaagtgac tggacttgtc cctggcttag caccagagcc
    11521 attacatgta cgacagccag cttcacgatg atacttaact tccttctcag ttccgaagat
    11581 agcttcttca aaggtcaaat tgacacgata ctggagatca tctccttggc gaggagcgtt
    11641 tggattgcgc gaagaaccgc ctccgccgaa gaaacttgag aaaatatcct caaaaccacc
    11701 gaagccacct gccccattga aaccgccgaa accaccatct ccaccaaaac caccattggc
    11761 gcctgcagca ccatactggt cataggcagc acgtttttgg tcgtcactca aagtctcata
    11821 ggcttcttga acttccttgt acttgtcctc agcaccaggc tccttgttga tatctgggtg
    11881 atattttttg gaaagcttac gataagcctt tttgatttcg tctgccgaag cgtttttgga
    11941 tacccccaga cgatcataaa attcagtatt gttcataatt caagatacaa agggcgtcaa
    12001 acggacacag ccatctagga gttttgacga cggacgctta tgtcctagaa aaaactatct
    12061 ttttggcaca gtccgtagcc cgtgttcagt tacgaacacc cttattcctt tctattgatg
    12121 ttctgaatcg aaccaccatt taggtcggat tcaattcctt tcttttatat ttagtaagaa
    12181 attctgaaac ccgtgttcag ttacgaacac tctttgttcc tttctattga tgagacaaaa
    12241 cccaaacaaa tgagattccg tcccttttta tcgaaaaaca gaggctgggt tgcaacctct
    12301 gcaaataagt aaattaactt tattttgatt ttaaatatcc tataagtaca gaaatattta
    12361 tatatttttg tctcttctta gtatttgcct atataattcc aattgatcat aagaaataca
    12421 actactgtcc aaatcatacc aattatgaac ggtattacaa atttatatgt ttgtatttct
    12481 aatgatatca tagctgatac catcgccgat acaaatgcag acaacaatac tgaagtaaca
    12541 aaattcctta ccgcttcatc atttttgaca caactatcat gctcagctaa tataatttct
    12601 ctatatatag tcaaacattc tactggaata ttatctatga aaccttttgc tgcttcatag
    12661 ttgtcagctt gattacaaaa atcattataa acttttcgtg tattttttag atactcatca
    12721 tccaatacac tcatcttatt tttccgtaaa ctctccgtct acgacgtcat cgcctgcgtt
    12781 tcctgttgct tgtgcgcctt ctgctccttc ttgagcttgt tgcgctgctg cggcttgttc
    12841 gtagagtttc acagcaaggc cttgagcttt ttcgttcaac gcttcaagtt tcgctttcat
    12901 gtcgtccaag ttgttgtctt cttgagcttt cttaaggtca tcaagggcag cttgggcagc
    12961 gtcacgttct gcgtcgaagc ctttaccttc agtttccttg attgtctttt cagtcgcaaa
    13021 gattgcttgg tctacttcat tacgaaggtc tacttcttct ttacgtttct tatcagcttc
    13081 agcgtttgct tctgcatctt tcatcatgcg gtcgatttct tcgtcagtca aacctgagtt
    13141 cgattggatg acaatagttt gttctttttg agttccaagg tctttggcct taacagacac
    13201 gataccgttc ttgtcgatgt caaatgttac ttcgatttga ggaattccac gaggtgcagc
    13261 tgggatatca gtcaattgga agcgtccaag agtcttgtta tctgctgcca ttgggcgttc
    13321 accttgaaga acgtggatat caacggctgg ttggttgtct gctgctgttg agaagacttg
    13381 tgatttagat gttgggattg tagtgttgcg atcgataagt tttgtaaata ctccacccat
    13441 tgtttcgata ccaagtgaca atggcgttac atcaagaagg acaacgtcct tgacatcacc
    13501 agtaatcaca ccaccttgga tagccgcacc catagcaact acttcatcag ggtttactga
    13561 tttgtttggt tctttaccag tttcagcttt aacagcttca acaacggcag ggatacgagt
    13621 tgaaccacca acaaggataa cttcgtcgat ttctgacaag ctcaaacctg catctgaaag
    13681 ggcttgacga actggaactt ttgtacgttc aacaaggtca cgagtcaaat cgtcaaattt
    13741 cgcacgagtc aaagtcattt ccaagtgaag aggtccagcc tcacctgcag tgataaatgg
    13801 caagctgatt tgtgttgaag ttacaccaga aaggtctttc ttcgcttttt cagccgcatc
    13861 tttcaaacgt tgcattgcca tcttgtcagt agacaagtcg ataccgtttt ctttcttgaa
    13921 ttctgctacc aagtggtcaa tgattttttg gtcaaagtcg tcaccaccaa gtttgttgtc
    13981 ccctgcagtt gacaatacgt cgaagacacc gtcacccaat tcaaggatag agacgtcgaa
    14041 tgtaccacca ccaaggtcaa ataccaagat tttttcttct ttgtcagtct tgtccaaacc
    14101 ataagcaaga gctgctgcag ttggttcgtt aacaatacgt tctacttcaa gaccagcaat
    14161 tttaccagcg tcttttgttg cttgacgttg agcgtcgttg aagtaagccg gaactgtgat
    14221 aacagctttg gttactttct caccaaggta gtcttcagcg tagcctttca agtattgaag
    14281 gatcatagct gagatttctt gtggagtgta ttcttttcca tttgcagaaa ctttttcaga
    14341 agttcccatc ttagatttga tagagataac tgtatctggg tttgtaactg cttgacgttt
    14401 tgcagcatca ccaacgatga tttctccgtt tttgaatgag actacagatg gagttgtgcg
    14461 gtttccttct gggtttgcga tgattttgct ttcagttcct tcaagaactg caactgctga
    14521 gtttgttgta cctaagtcaa taccgataat tttagacatg tgtttttctc cttgttagtt
    14581 aattttctat ttttcttttt gatactcttc ttaagtggcg acgccgtcag agcttgactt
    14641 cgtcaatctc tttgactaaa ctttgagcct aaggtctcaa aatttgcgca aatagcacca
    14701 cggcgaagag tatcgtcttt ggttcgcttc gctcactatt acaaagccaa acatatttta
    14761 tctttcttca tagtttattg tcgtttcgga caagttttct attatgtaaa ttgcgacacg
    14821 aggagtcgaa atcgatttta tttcgacgac gagttagtaa ggaagctagg caaacgtcat
    14881 agcgattgcc gttttctgac gagttgcttt agctaccgtc agaattgccg aatcgaacac
    14941 gccctaagct ctgagtaaaa aagatagatt ttcttgtgtt catcgaacac ttcgtcaatc
    15001 tcctattttt actgcgagct ttttacgagc tttgtatctt agttatacac cactaccatt
    15061 gctgggcgta ggatgcggtc atggagtttg tagccttttt gaaagacttg ggcgatggta
    15121 tctactgggt gttcatcgtc tgctgggaga gtttggatgg ccatatggta gttatggtca
    15181 aattcgccat ctgctgcgat ttcttcaatt ccttcttctt tcaaagcgtg aatcaagctt
    15241 tcttgcacca tcgccaagcc cttcttcaca tcatctgtca aaccttcaac tgcaagtgca
    15301 cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca agtcctggct acgataacgt
    15361 tgcaagtttt gacgttcttc attggcacgg cgttggatat tttgcatttc tgcatgagcg
    15421 cgaagatatt tgttttcgaa ctcatctgca cgttcatttg ccaagtccaa ctcagacttt
    15481 tcaggagttg tttcttcagc tgtttccaca acttcctctt cttgaacttc ttctacttct
    15541 tcatttttta tatcttgggc catgttcgcc tcctttaatg atttcaatct taatgtactt
    15601 cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa cttcatggtc aaaacacggt
    15661 tgaccacatt gatttgattg attagctgtt ggtaatccag attaactgga ccgataatgg
    15721 ctagaattcc aactcctcga taaggaatga ggaacttact actaatcact gctaggtcag
    15781 ctaaacagga ctcttgaccg tctgcaacac gaacattttg catctgatcc tcacgcaacc
    15841 cctcacgaat ctccaaggcc accttttgcg gttggtcaaa gaactgatag gctgctagat
    15901 tggcaaaatt caagagatgg accttgcccg ccatcacaat gttttcgttg aacatttcct
    15961 taaagatgtg ttcaaagaga tcgatgacat tatccgttgt tgtaaagtaa cgctggataa
    16021 tctgcggaat ctccgtccga atcttgtagt gaatatctaa aacggtgtga ccgaggaaac
    16081 gttcctgaat gatgctcttc agtttcagca aatcctcctg caagaagttc cttggaatca
    16141 gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa taccgccaag gctgtatgtt
    16201 gccccaaaac aacgatatca aaggctgtca aacgttgcct gctcggctca acatccagtg
    16261 ccactaccgt acagccactc aggtctgtta gtaagttagc agcctcttgc agaatatcct
    16321 ccaatttgaa gaattcctga tcaaaggctt tgacaatctc atatacctca ttttcagcca
    16381 gccggtcaaa atccagtgag tgtttcacat agtactgaaa accagcaaca cttggcatcc
    16441 gaccgcttga agtatgagcc ttctcaagca acccttgttt ttctagttcc gccatgtcat
    16501 tacgaatggt tgcactgcta gagttaatag actcttgcaa ggcttttgat ccgacaggtt
    16561 cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat atcctgctga cgctctgtaa
    16621 ccatctcatc actcctctct gtctgatcaa ttagcactca atgcatccaa gtgctaactc
    16681 atgattctat tatacaccct tagaagagaa tgtcaagaca aaaactcaaa aaattagcac
    16741 tcttttatca agagtgctaa aaatcaatct gaagacctag aaccttgcta ttcatctact
    16801 cggtatttcc tttttagtct gaaataacca taaattagat aagaaatcag aaaagcatat
    16861 aaaacaaaaa taagaaagaa agacatagaa agatcctctc taaacaaact catacaaaca
    16921 acaagaccac ctgagaaagt agctgtacag gaacgaagtc tagattgcat aacttcccat
    16981 ttgagccctt tactcataca gacttgatcc tctggaagta aatcagaaga cgatttacga
    17041 agaatcgaac aagaacctac tcctatcaat tcccaacctc tatctctaaa atcttgcagt
    17101 tcatgcttat acttttttaa gaaatctaga atcatagata cggtagatga catcgtctgg
    17161 ttgacattgg tcaaaataga acaaaccaaa acgactcgtt ctatacctcc aacctttcaa
    17221 atgcatctca tgtaaatgtt cttcttcctt gtccaaatca acaatggtga aaatccgaaa
    17281 ttctactctg ctattcattg tcttacccca aaattagaaa acatgcctgg cgttatttat
    17341 tagataattc tttccacttt tgactcaatc tccaaaaaat ataagaaatc tgaatcgcaa
    17401 aaactatcaa taaaacccaa tctattatga aaatcaaaaa cactttccaa ctgaaagaac
    17461 tacctccagt gacaaacttt gagaaaaacg gtagtagagc taaaaagaga aataaaatag
    17521 gaagcatccg cattgttaaa atccgtttgg cataaaaaaa tctttattta aacgaaaata
    17581 ttatggcaaa atttacgcca gtttttgaac ggctgatgta gatattttat actttcaaaa
    17641 tgtttaaatg tgattattta tttttgaaaa atagatcacc agcccgactg aaagtgctta
    17701 tagaatgata ataagtcgcc tgccgaaaac agcgaaaaat agcggtgtta tgcggagata
    17761 atctgacgcg atgcgaaagt atattgcata cttattttca acaatttagc agagtatttt
    17821 tataagtgtg atataataga agtataattt gttctgatag tttattttat ggagaagtag
    17881 atttttagaa tgcggagggt tcaatatggt tgagtttata aagtctaaga aagaaatgag
    17941 tgaggaggat attaaagcaa atttcatcac tcctgctatt gtatccaaag gatggaaaaa
    18001 tggtgagcat atcgcttacg aagaatactt cactgatggt cgaattgaag ttagaggaga
    18061 taaggctcat cgtaaagaag gaaaaaaatc agactattca ctgtattacc aatttggaac
    18121 tcgaattgca attgttgagg caaaggataa taaacacagc gttcgagcag gattacaaca
    18181 agctattgaa tatggagaga ttttagatgt tccatttgtt tattcttcga atggtgatgg
    18241 ctttattgaa cacgaccgta tcacgagaga agaacgtgag ctggagttag acgaattccc
    18301 tactcgtgaa gaattatttt ctcgtatgac gaaggaaaaa ggattgacgt acgaaattac
    18361 agaagctatc tcaactccat actatacaga cgccttctca atgaaaacgc cacgctatta
    18421 tcagcaaata gctatcaacc gtactattga aacagttgcc agaggacaaa aacgagtaat
    18481 gtttgtgatg gcaacaggaa cggggaaaac gttcatggct tttcaaatta ttcatcgcct
    18541 tcgaaaagct ggtttggcta aacgagtttt attcttagcg gatagaaaca tcttagtaga
    18601 ccaaacgatg gctgaagact ttaggccatt cgaaaaggta atgacgaaaa ttacaccaaa
    18661 acttttgact gctcctgaaa aattaaattc ttttgaaatt tatctagggc tttatcagca
    18721 actaactggt gaagatggaa ctgaaacaca ttatcaaaaa tttgacaaag acttctttga
    18781 tttaatcgta attgatgaag cgcaccgtgg ttcagctaag gaaaacagta actggcgtaa
    18841 gataattgat tatttcagtt ctgcgacaca gattgggatg accgctactc ctaaagaaac
    18901 caagaatgct tccaatacgg aatactttgg tgagccaatc tatacttata gtttaaaaca
    18961 gggaatcgag gatggttttt tggctccata tcgtgttatg agagttaatt tagatgtaga
    19021 tgtggatggt tatcgtccag aaactggaaa agttgatgct aacggacaat taatagaaga
    19081 taggtactac ggcaggaaag attttgataa aaccattgtc attgatgata gaacgcaaag
    19141 agttgccaag tttgtttctg attatatgaa gcaaaacaat gcacgatttg ataaaacaat
    19201 tgttttttgt gttgatattg accatgccga gcgaatgcgt gctgcacttg taaaagagaa
    19261 tctagactta gtccaagaag actatcgtta tgtcatgcaa gtaactggtg acaacgctga
    19321 aggaaaagct caactggata actttatgga tgtcaattct aattttcccg ctattgtaac
    19381 aacgtctaaa ttattaacga caggagttaa tgctaaaaca tgtcgtttga ttgttttaga
    19441 ctctaatatc caatccatga ctgaatttaa acaaattatt ggtcgtggca cacgtcttta
    19501 tcctcaaaag gggaaagaat tttttacgat tattgatttt cgaaatgtta ccaatttgtt
    19561 tgctgaccct gattttgatg gtgatccagt gaaggtgctg gaaacaggtg cgaaaacagt
    19621 cagtggttct acgcccggtt tcgtaagtga ggaaggtgac ccagtagaaa aatatatcgt
    19681 tacagacaag caggttacca ttcttaattc tactgttcaa gtattggatg aaaacgggaa
    19741 actgattacc gaaagcctga ccgactacac tcggaagaat atcttaggta gctacgccac
    19801 tttgaacgat tttatcacag tttggcatac ggcggataaa aagaagctta tcttagacga
    19861 actttataaa aaaggagttt atctagatgc tattcgagag tcggagggaa tatcagaaca
    19921 agaaatcgat gattttgatt tactcctaaa acttgcctat ggtcaaaaag aattaaccaa
    19981 aacggaacgt atcaataagc tcaaacaaag cggatattta tataaatata gtgaggaagc
    20041 gcgtgctgtt ttggaaattt tactgaacaa atacatggat aaaggtattg gagaactcga
    20101 aagcattgaa acattaaaac ttccagaatt tcagatatat ggtggaacct tcaaaatcat
    20161 caatacttat tttggagata aaaaacgata tttacaagca attaaagaat tggagcaaga
    20221 gctatttaca gtagcttaat gaaaggaaag tatgtcaatt acatcatttg taaaaagaat
    20281 tcaagatatc actcgaaacg atgctggtgt taatggtgat gctcaacgta ttgagcaaat
    20341 gtcttggtta ttattcttaa aaatttatga tagccgtgaa atggtttggg aattagaaga
    20401 agacgagtat gagtcaatta tcccagagga attaaaatgg cgaaattggg ctcatgctca
    20461 aaatggggaa cgggtattga caggcgatga attacttgat tttgtcaata acaagttatt
    20521 caaagagttg aaagagcttg aaataacttc aaatatgcct attcgaaaaa cgattgttaa
    20581 atcagctttt gaagatgcga acaactatat gaaaaatggc gtcttgttac gccaagtcat
    20641 caatgctatt gatgaagttg atttcaatag ccctgaagat cgtcattcgt ttaatgatat
    20701 ttacgaaaaa attcttaaag atattcaaaa tgctgggaac tcaggagaat tttatacgcc
    20761 acgtgcagcg actgatttta ttgccgaagt tcttgaccca aaacttggag aatcaatggc
    20821 agaccttgct tgcggaacag gaggcttctt gacttcgact ctgaaccgtt taagtagtca
    20881 acgtaaaact agtgaagata ccaaaaaata taatacagct gtttttggta ttgaaaagaa
    20941 agcatttcct catcttttag cagttacaaa tctgtttctt cacgaaattg atgaccctaa
    21001 aattgttcat ggaaatactt tggagaaaaa tgttcgtgaa tatacgaatg atgaaaaatt
    21061 tgacattatt atgatgaatc caccttttgg agggtcagaa ttagaaacaa taaaaaataa
    21121 ctttccagca gaattacgga gttctgaaac agctgattta tttatggctg tcattatgta
    21181 tcgtttgaaa gaaaatggtc gtgttggagt tattttacct gatggttttc tatttggtga
    21241 aggtgtaaaa actcgcttga aacaaaaact ggtagatgag ttcaacttgc atacgattat
    21301 taggttgcct catagtgtct ttgcaccgta tacaggaatc catacgaaca ttcttttctt
    21361 tgataaaaca aagaaaacag aagaaacttg gttttatcgt ttagatatgc cagatggtta
    21421 taaaaatttc tcgaaaacta agccgatgaa gtcagaacac ttcaatcctg ttcgtgactg
    21481 gtgggaaaat cgtgaagaga ttctggaagg taagttctac aaatctaaat catttacacc
    21541 tagtgaattg gctgagttga attataattt agaccagtgt ggttttccaa aagaggaaga
    21601 ggaaatctta aatccctttg agttgattca gaattatcaa gcggaaagag caactttaaa
    21661 tcataagatt gataatgtat tagctgatat tttgcagttg ttggaggaca aataatgaca
    21721 ccagaacaac ttaaagcaag tattctccaa agagcgatgg aagggaaatt agtgccgcaa
    21781 aatcccaatg acgaacctgc aagtgaatta ttaaagagaa ttaaagctga aaaagaaaaa
    21841 cttatcagtg aaggaaaaat caaacgagat aaaaaggaaa ctgagatatt tcgtggtgat
    21901 gatgggaaac attatgggaa gtttgctgat ggaagtactc aagaaattga tgttccttat
    21961 gatattcctg atacttggga gtgggtgagg ttttctacat tggttgaaat tgtcagaggt
    22021 ggctctccac gaccaatcaa agattatctt acttctgaag tagatggaat aaattggata
    22081 aaaataggtg atactgaaaa gggtgaaaag tatataaata atgttaaaga aaaaatcaaa
    22141 aaatcagggc ttaacaaaac tagatttgta aaaaaaggta catttttgtt aactaattct
    22201 atgagttttg gtagacctta tattttgaat gttgatggtg caatacacga tggatggttg
    22261 gctatttcga actatgaaaa ctcattaaat aaagattatc tattctatat tctttcatca
    22321 aatgtagttt attctcaatt tctatctcta attagtggag ctgttgtgaa aaacttgaat
    22381 agtgataaag ttgcttctat tcttatccct ctccctccac tatccgaaca acaacgaata
    22441 gtagaagcaa tcgaatcagc t
//
LOCUS       DAVMCN010000026        22301 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVMCN010000026 DAVMCN010000000
VERSION     DAVMCN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.026"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            58..354
                     /locus_tag="VYP85_001215"
     CDS             58..354
                     /locus_tag="VYP85_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1881737.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGKGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            475..1419
                     /gene="manA"
                     /locus_tag="VYP85_001216"
     CDS             475..1419
                     /gene="manA"
                     /locus_tag="VYP85_001216"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1881738.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGIFILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1440..2918)
                     /locus_tag="VYP85_001217"
     CDS             complement(1440..2918)
                     /locus_tag="VYP85_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1881739.1"
                     /translation="MVFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIISRGVQKGIERASKVMMPL
                     LFIIFVFIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSLWSSLPNLCNQKGLE"
     gene            3001..3755
                     /locus_tag="VYP85_001218"
                     /pseudo
     CDS             3001..3755
                     /locus_tag="VYP85_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(3775..4230)
                     /locus_tag="VYP85_001219"
     CDS             complement(3775..4230)
                     /locus_tag="VYP85_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1881740.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4250..5425)
                     /locus_tag="VYP85_001220"
     CDS             complement(4250..5425)
                     /locus_tag="VYP85_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1881741.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEKNREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5484..6329)
                     /locus_tag="VYP85_001221"
     CDS             complement(5484..6329)
                     /locus_tag="VYP85_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1881742.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAENIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6454..7011
                     /locus_tag="VYP85_001222"
     CDS             6454..7011
                     /locus_tag="VYP85_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1881743.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7030..7497
                     /locus_tag="VYP85_001223"
     CDS             7030..7497
                     /locus_tag="VYP85_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1881744.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7586..8215
                     /gene="upp"
                     /locus_tag="VYP85_001224"
     CDS             7586..8215
                     /gene="upp"
                     /locus_tag="VYP85_001224"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1881745.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8389..8979
                     /gene="clpP"
                     /locus_tag="VYP85_001225"
     CDS             8389..8979
                     /gene="clpP"
                     /locus_tag="VYP85_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1881746.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9058..9306
                     /locus_tag="VYP85_001226"
     CDS             9058..9306
                     /locus_tag="VYP85_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1881747.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9407..10567
                     /locus_tag="VYP85_001227"
     CDS             9407..10567
                     /locus_tag="VYP85_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1881748.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10835..11704
                     /locus_tag="VYP85_001228"
     CDS             10835..11704
                     /locus_tag="VYP85_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1881749.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLVTAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11708..12664
                     /locus_tag="VYP85_001229"
     CDS             11708..12664
                     /locus_tag="VYP85_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1881750.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAVVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12664..13428
                     /locus_tag="VYP85_001230"
     CDS             12664..13428
                     /locus_tag="VYP85_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881751.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPVFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13428..14138
                     /locus_tag="VYP85_001231"
     CDS             13428..14138
                     /locus_tag="VYP85_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881752.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14446..15102
                     /locus_tag="VYP85_001232"
     CDS             14446..15102
                     /locus_tag="VYP85_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1881753.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15210..16305
                     /gene="prfB"
                     /locus_tag="VYP85_001233"
     CDS             join(15210..15281,15283..16305)
                     /gene="prfB"
                     /locus_tag="VYP85_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1881754.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16323..17015
                     /gene="ftsE"
                     /locus_tag="VYP85_001234"
     CDS             16323..17015
                     /gene="ftsE"
                     /locus_tag="VYP85_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1881755.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17008..17934
                     /locus_tag="VYP85_001235"
     CDS             17008..17934
                     /locus_tag="VYP85_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881756.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANAPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18220..20400
                     /locus_tag="VYP85_001236"
     CDS             18220..20400
                     /locus_tag="VYP85_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1881757.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20452..21267
                     /locus_tag="VYP85_001237"
     CDS             20452..21267
                     /locus_tag="VYP85_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1881758.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            21473..>22301
                     /locus_tag="VYP85_001238"
     CDS             21473..>22301
                     /locus_tag="VYP85_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1881759.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVTSGVDLPKFIQKKA
                     PKDGSTYFNRTRVFAEEPTTKTYIDSVNDGTWTFKGYDAASAVVNKANVEFVGKWEFK
                     "
BASE COUNT         6845 a         4175 c         4871 g         6410 t
ORIGIN      
        1 ttatataatg ctttttgatt ttagtttagt attatcgtag aaaatggact cggtgctatg
       61 gatacaccgg atgagaatgg ttatgtagca gataactatc ggattactta cttagaggcc
      121 cacatcaagg ccatgcgaga tgccatttac caagacgggg ttgacttgct tggttatacg
      181 acttggggct gtatcgatcc ggtttcagct ggcaaagggg aaatgaataa gcgctatggc
      241 tttatctatg tagatcgaga taatgtagga aacggagctc tcaaacgtag caagaagaag
      301 tccttctatt ggtacaagga tgtcattgat agcaatggtg caagcatcgg gtagagcaca
      361 tttgtttact atttttataa aatcttctcc ctgctttata agatgtaaaa aagagttcaa
      421 ttcgaactct ttttttgcta taatgagggg agaaaaatca gacaggagat cgacatgtca
      481 gaaccattat ttttacaatc agttatgcaa gaaaaaatct ggggtggagc caagctacgt
      541 gatgagtttg gctacgacat cccaagtgaa aaaatcggag aatattgggc catctcagcc
      601 catccaaatg gagtctctaa agttgccaat ggtcgttacg agggaacaga tcttgctact
      661 ttgtatgcgg aacaccgtga actatttggc aatcgtccag aacctgtatt tccacttttg
      721 accaagatcc tcgatgccaa cgactggctc agtgtccaag ttcacccaga cgatgcttat
      781 ggactcgagc atgaaggcga actcggaaaa acagaatgct ggtacattat cgcagcggat
      841 gaaggttcag agattatcta cggtcacaat gccaagtcaa aagaagaact ccgccagcaa
      901 atcgaggaca agaactggga tgacttgttg accaaagtcc ctgttaaggc tggagatttc
      961 ttctatgtac caagcgggac tatgcacgct atcggggcgg gtatcttcat ccttgaaacc
     1021 cagcagtcta gcgataccac ctatcgcgtc tatgactttg accgcaagga tgacaaaggc
     1081 aacttgcgtg aacttcatct tgaaaaatcc atcgatgtct tgaacattgg tgagccagca
     1141 aatagccgtc ctgtaactgt taaagcagat gatttgcgtt ccactctcct tgtatctaat
     1201 gatttcttcg cagtttacaa gtgggaaatt actggaaaag ttgactttga aaagacagct
     1261 gactacagct tattgagtgt cttagctggt caaggtcagc taactgttga cgggaaaaat
     1321 tatccaattc aaaaaggcag ccactttatc ctaccaagtg atgttgaagc ttggactctg
     1381 gaagggcaag gtttggaatt gattgttagc catccataaa aagaaagggc ctgagttcac
     1441 tactcaagtc ctttttgatt acataaattg ggcaatgaag accacaatga tgatgattgg
     1501 aatgacggaa cgaagaaacg aagaaggaag agccagactt ggaacagtcc ttgtttccat
     1561 gctctttcat cgagatggag ttcctccatt gcaagagcct ttttaaagat atagcctgta
     1621 aaaagtgaaa ggtagagagc tccaaatggc atgaggagat tggaaaccaa gaagtccata
     1681 gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca tgacaccgta agatagggct
     1741 gaaggaatgc caaagacaaa ggtcaaaatt cctaaaataa cactccattt ggcacgtttg
     1801 ctgttatcct ggttggtgat attgcccaca ttgatctcca gcatcacgac agaagaagtg
     1861 acagtcgcaa agaggaagag gacgtagaaa atggttccaa aaggcatctt gtcaaagagt
     1921 tgaggcaaga cgataaagag caggctgggt cccccttcag actggatatt gaagggggat
     1981 cgagcttgga aaatggctag acctgccatg atggatatcg agatattcat ggctacgatg
     2041 gagattcctg actggactag attggttttc ttgtccaagt aagaagcata ggtcaacatg
     2101 actgtaaccc ctagtgagag ggcaaagaaa gattgtccca gagcatagag gagaccagcg
     2161 ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa ccccttccat ggcatttggc
     2221 aaactgagag agcgaccgat gataaaaaca aagatgataa agagcagggg catcatgact
     2281 ttcgaagctc tttcaatccc tttttgaacc ccacgtgata taataaagat atttaataag
     2341 ataaaggctg cttgagctac tagggcaatg gctggatttg aaatgattga agtaaataac
     2401 tgagcataat cacccgttcc accaagttgg aacaatttcc caaactcaat acctagatag
     2461 actagaatcc atcctccgat aacactgtaa aaagataaga ggataaagag ggcaaaggcg
     2521 ccaatccaac cgataaagtt gtacttgtta ttcttgccca gttttccaaa ggttttgata
     2581 gcggaaacgc cagcactacg gccaagggca aactcagcca gcaggagagg gaaaccgatt
     2641 aaaatagtgg aaatgagaaa gattagtaaa aagcctccac cgccattagc agcagtcatg
     2701 tagggaaact tccaaacgga accaagcccg atggccgagc cagcagatgc tagaataaaa
     2761 ccaagtttcg acccccattg tgatttttct gacatagtta aactctgatc tcctttttca
     2821 aaataagaaa aagctacttg agttgtcaaa tagccttctg tttgattgat agacttgact
     2881 atcctatcat gttttctaag gtctgtcaag aaaaccattt tcaagttttc acacctttct
     2941 caaaaacgct tgactctgac ctaaggggag gggttatact atcattgtaa ggaggaaatc
     3001 atgtaccata taaaagaagc tgcgcagctt tcaggtgtct ctgtcaagac cctgccctgc
     3061 atcactatga caagatagga ctcttggtcc ccttaaagtc ggaaaacggc tatcgaacct
     3121 atagtcaaga ggatttggaa cgccttcagg tcattcttta ctacaaatat ctaggctttt
     3181 ctttagagaa aatagcagag ctgttaaagg aagaaaggac agatttattg ccccatttaa
     3241 ctaggcagtt ggactatcta actcgcgaaa ggcaacatct ggataccttg atttccacct
     3301 tgcaaaaaac tattcaagaa caaaaaggag aaagaaaaat gaccattgag gaaaaattca
     3361 cgggatttag ctatcaagac aatcaaaaat accaccaaga agcggtagag aaatatggtc
     3421 aagaagtcat gggacaagcg ctcgaacgcc aaaaaggtca cgaagacgag gctacggccg
     3481 cctttaacca agtctttcaa actttggcac aaaatcttca agttggttta cctgcaacag
     3541 caaccgaaaa ccaagagcaa gcagccaagc tcttgcaagc cattcgcact tatggatttg
     3601 actgctctat tgaggtattc ggtcatatcg gtaaaggtta cgtctacaac ccagagttta
     3661 aggaaaacat tgacaagttt ggttctggaa cagcccagta cacgtcagat gccattgcag
     3721 cttacgttca gacaaatgca gaaaaaatag gctaggaatt tcctagccta ttttttactt
     3781 caaatcataa agccagtcgt caccgttttt gtagtaaaag aattcactga gatcttcttc
     3841 tagaaacaca cgaagcatat cagacatatc atcggttgca agttttagat gagaaagatt
     3901 ttcaaagtcc tcccaccaaa ctttcccttc gtctgaagac tggagttcac cagtaaagtg
     3961 ttctgtcttg taaaaaagga cgacataacg ataatccttg tcgtcatacc agtttttgat
     4021 accacagagt tggggtttgg aaatgatcag accagtttct tctttcactt cacgaatgac
     4081 agcatcgaca aaggattcgc cacgttcaac atgaccacca ggaaaagtaa tgccaggcca
     4141 gtcgggacta actcggtctt ggaccaggac cttatctccg tttttaatca tacacatgtt
     4201 aacaaattcg actgcctctc ttctgttcat tcttcacaac ctttaatctt taatcataat
     4261 gcagacttcc cgccacccag ccggtacaga gggcagaagt gatgttaaag ccacccgtgt
     4321 gggcattgat atccataact tcgcctgcaa agtggaggcc aggtaccagc ttactttcaa
     4381 gggttttagg attgatttcc ttgagactga ctccaccctt ggtaacaaag gactttgcaa
     4441 gggacatttt tccagttaca ggaattttaa gttctttaat ggactggaca agctgttctc
     4501 gttccttttc agtcagctgt ttgacttttt caggatatcc ttgtacaaaa aattcggcca
     4561 agcgttctgg taacaaggtt tttaaagcgt ttttcaagga tttttcccga tttttttcta
     4621 gaaatgtaac caagtccttc tcagaaagtt gaggcaaaac atcgagtgag agaacctccc
     4681 cacctttgac aaagctagac atgcgtaggg cagcaggacc tgacaaacca aagtgggtaa
     4741 agagtaaatc atgagtgatg acatgcttac cataacttag ggtcacatcg tccaaagaaa
     4801 tcccttgtaa ggctttatgt ggaaaatctg ttaataaagg actttcagca gcctcaagat
     4861 cggtgatggt atgcttaaaa tggcgagcaa tctcgtgacc aaaaccagtc gaaccagtcg
     4921 aaggataaga cttaccacct gttgtgacaa tgagtttctc acaagtgaag gtttgatccg
     4981 ctgacttaag gacaaactgg ttatctactt ttttaacaga aacgatttct atttgagtag
     5041 caacttgacc acctagttcg gtgattttct tttccaaagc ttcgataata gtccgagact
     5101 tgtcactggc tggaaagacg cgtccgtggt cttcgacctt aagtttaaca ccattttctg
     5161 taaaaaagtt gatgatgtca tgattatcga actgggagaa aacactgtaa agaaagcgtc
     5221 cgtttccagg aattccagct agcaggttgt ctaagctacc attgttggtc acattgcaac
     5281 gtcccccacc agtcccagct aatttttttc caagtttccg atttttttcg atgaggaggg
     5341 ttttctgtcc ataaaagcta ctggaaatcg tagccatcat accagcaggt cccccaccga
     5401 tgacaatagt atcaaaatgt ttcatagctc tattgtacca caaaaaaaca agagatgatg
     5461 gtcacctctt gtcaagaatg caattaatca atttcatagc ccatcagcaa accgccctct
     5521 tctgcataga aactgcagag accagaggtt ggtagaattt taatatccgc ttgtgggaag
     5581 gtttcacgga ttcgctctga gagctgttga caacattttt cgttattgcg ttgggccatg
     5641 acaatacggc caccagcata tccagctttt actaactcat cataggcagc ttgaactgat
     5701 ttctttgatc cccttgcttt ttgtagcaat tcgagagttc cagtttcact agcttttccg
     5761 accatacgaa tgttgagaag gccaacgacc gtaccgataa gcttgctcaa acggccgttc
     5821 ttcaccaagt tatcgacttt ggctaggaca aagagcaact tagttttttc ttgataggcg
     5881 gtgatagctt caaccacttc ttcaaaagac aagccttggt caatcaagtc attcaatttt
     5941 tctacgagta ggtcaacttc accaccagca gataaactat caatcacatg aatcttagtg
     6001 tcaggatggt cttccagata aatattcttt gctagttgag cactattgtg actgccagaa
     6061 agggtacctg tgatggttac taggaaaatg ttttcggcac cttcaaatgc tcgcaaatag
     6121 tcatctgggc ttggacaagc tgattttgaa gcttctgcag ttgcatacat ggtttccatc
     6181 atttggtcaa tatcgagact ggcgtcatca acaaagacct gatcagctac ttgaatggtt
     6241 aaggggacac ttacaaaggt tgtgttaata gctggtgttg gcagttgacg ataatcacaa
     6301 ccagagtcag caataatctt ccaagtcata gaaattctcc atctttgtca gttatacatt
     6361 gacaaaggtt ctgtcttttt ttacaattat atcatgaaaa ctcttgaaac aaaagcatca
     6421 tccgtctgtt gtgacaagta gaaagaaaat gttatgtctg aacgtagaat ctctgaaaag
     6481 tctcttgaaa atctcagaaa atcaaaccaa gaatccaatt tattaaccag agaagccatt
     6541 gaaacagccc tcttgcaact cttggaaaaa aaggagctga ccaagattag tatttctgaa
     6601 ttggtcaaac gtgcaggtgt ttcgcgtgcg gccttttatc gcaattatga ctccaaagag
     6661 gaaattttag agagcgtctt taaacgaact gtccacaata ttatggaaca gctgcatcat
     6721 tacgatttaa agacagacct ttatttggtt tgggttcacc ttttccggga ggccagaaag
     6781 gaagctagag taattcaatt ggccttggat taccatctgg aaaaaatctt tgtccaagcc
     6841 atgcaggaat ttctagaaaa ataccatggg aaatcaaaag gtgtcagctc ttatcttcat
     6901 tccttctgga gctcagccat cgtctctgtc cttctaaaat ggatcaagga tggcatgaag
     6961 gtaccagctg aaaagattgc agatttaggt ttaccatttt ttaaaaaata gagaaaaagg
     7021 agaaaagaga tgactgaaaa aagactggcc tgggatgagt attttgcagc ccaagcccta
     7081 ctaattgcga atcgttccac ttgtaaacgt gctaaagtgg gcgcgattct ggtaaaagat
     7141 aataaggtta tttccactgg ttacaatggt tcggtgtcag ggactgagca ttgtattgat
     7201 cacgaatgtt tggtcattga aggccactgt gttcgcaccc ttcacgctga ggtcaatgct
     7261 atccttcaag gtgctgagcg tggtgttccc aaaggcttta cagcctatgt aacccatttt
     7321 ccttgtctca actgtacaaa acaattgctt caggtcggct gcaagcgcgt ggtttatatc
     7381 aaccagtacc gaatggacga ctacgcccaa tacctttatc aagaaaaagg gacagaattg
     7441 acccatttac cacttgagac agtacagaca gctcttaaag aggctgatct aatgtaaaaa
     7501 ttatcaaaaa taaatggctt agaaagattt ttaaaccgtt ttttggtata ataagaagaa
     7561 taaattgaaa gaaggaattc caaaaatggg aaaaattgaa gttattaatc acccactgat
     7621 tcaacacaaa ttgtcaatct tgcgtcgtac agatacttct acaaaagctt ttcgtgagct
     7681 agtagatgag attgcaatgt tgatggggta tgaagtactt cgtgatcttc cactagaaga
     7741 tgtggaaatc gaaacaccaa ttacaaaaac agttcaaaaa caattggcag gtaagaaatt
     7801 ggccatcgtc ccaatcttgc gtgcaggtat cgggatggtt gatggtctct tgagcttggt
     7861 tccagctgct aaagttggcc acatcggtat gtaccgtgat gaagaaacac ttcaaccagt
     7921 tgaatacttg gtgaaattgc ctgaggacat tgaccaacgt caaatttttg tagtagaccc
     7981 aatgttggca acaggtggct cagcaatctt ggctgttgat tctcttaaaa aacgtggcgc
     8041 atcaaatatc aaatttgtct gccttgtatc tgctccagag ggtgtaaaag cccttcaaga
     8101 agctcatcca gatgtagaaa tctttacagc agccttggat gaacgtttga acgaacacgg
     8161 ttatatcgtt ccaggtcttg gagatgctgg agaccgcttg ttcggtacaa aataagatcg
     8221 aaaagaagaa tgacttggaa aagtatttcc agtcacgaaa ggaggttggg tttttgtttc
     8281 tgtctaatga aagcagagca aaaatttgac cttttttgac caagatatta taatagtctt
     8341 atcttcagtc atttgaccaa caaaattaaa actcaaaagg agaaatgaat gattcctgta
     8401 gttattgaac aaacaagccg tggagaacgt tcttacgata tttactcacg tcttctcaaa
     8461 gaccgcatca ttatgctgac aggtccggtt gaagacaata tggctaactc tgttattgcc
     8521 caattgcttt tcttggatgc ccaagatagt acaaaagata tttaccttta tgtcaataca
     8581 ccaggtggtt ctgtttcagc tggtttggca atcgtagata ccatgaactt tatcaaggca
     8641 gatgtccaaa ccattgttat gggaatggct gcatctatgg gaacagtcat cgcatcaagt
     8701 ggagcaaaag gcaaacgttt catgcttcca aatgctgaat acatgattca ccaaccaatg
     8761 ggcggtacag gtggtggtac ccaacaaact gatatggcta tcgctgcaga acacttgctc
     8821 aaaactcgta ataccttgga aaaaatcttg gctgaaaatt caggtcagtc aatggaaaaa
     8881 gtccatgcag atgcagaacg tgataactgg atgagcgccc aggaaacact tgaatatggc
     8941 tttattgatg aaattatggc caacaattca ttgaactaat gatgatagaa ggcaaactcg
     9001 actgggtttg ctttttttgg tataataggg agagatttct tagaaagagg atttatcatg
     9061 tttgaaaaag tcaatcgctc tggcttgatt atctatcttt actataatcg tgatgccaaa
     9121 aaactgcagg attatggaga tattacctat cattccaaga aacatcgtta cttacaactc
     9181 tatgttccaa ctcaagaagt ggagcaattg gtcggacgct tgagcaagga aaaatttatt
     9241 aaaaaagtta gggtttgtca tatccaagag ttggaaacac cctttgtggg caatctttat
     9301 cgataggaaa acgttatcat cgaaaaagtt caaggaaaac attgacaatt ttctgataat
     9361 tcggtatatt cttaacagac tatttaagaa ataaggagac aaaaagatga agaaaaaatt
     9421 tgccctatcg tttgtggcgc ttgcaagtgt agcacttctt gcagcctgtg gagaagtgaa
     9481 gtctggagca gtcaacactg ctggtaactc agtagaggaa aagacaatta aaatcgggtt
     9541 taactttgaa gaatcaggtt ctttagctgc atacggaaca gctgaacaaa aaggtgccca
     9601 attggctgtt gatgaaatca atgccgcagg tggtatcgat ggaaaacaaa tcgaagtagt
     9661 cgataaagat aataagtctg aaacagctga ggctgcttca gttacaacta accttgtaac
     9721 ccaatctaaa gtatcagcag tcgtaggacc tgcgacatct ggtgcgactg cagctgcggt
     9781 agcgaacgct acaaaagcag gtgttccatt gatctcacca agtgcgactc aagatggatt
     9841 gactaaaggt caagattacc tctttattgg aactttccaa gatagcttcc aaggaaaaat
     9901 tatctcaaac tatgtttctg aaaaattaaa tgctaagaaa gttgttcttt acactgacaa
     9961 tgccagtgac tatgctaaag ggattgcaaa atctttccgc gagtcataca agggtgaaat
    10021 cgttgcagat gaaactttcg tagcaggtga cacagacttc caagcagccc ttacaaaaat
    10081 gaaagggaaa gactttgatg ctatcgttgt tcctggttac tataatgagg ctggtaaaat
    10141 tgtaaaccaa gcgcgtggca tgggaattga caaaccaatc gttggtggtg atggattcaa
    10201 cggtgaggag tttgtacaac aagcaactgc tgaaaaagca tcaaacatct actttatctc
    10261 aggcttctca actactgtag aagtttcagc taaagctaaa gccttccttg acgcttaccg
    10321 tgctaagtac aatgaagagc cttcaacatt tgcagccttg gcttatgatt cagttcacct
    10381 tgtagcaaac gcagcaaaag gtgctaaaaa ttcaggtgaa atcaagaata accttgctaa
    10441 aacaaaagat tttgaaggtg taactggtca aacaagcttc gatgcagacc acaacacagt
    10501 caaaactgct tacatgatga ccatgaacaa tggtaaagtt gaagcagcag aagttgtaaa
    10561 accataatag aaaaatgttg aaatagggaa tgagcctttg actcactccc tgtttcgata
    10621 tttaatactc ttcgaaaatc tcttcaaact gcgtcaacgt cgccttggat tatatatgtg
    10681 actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag
    10741 tttcctagtt tgctctttga ttttcattga gtataagaac ctatcaaaaa gtgagggaaa
    10801 accctcggaa ttataaatag aaagagtgaa tcttatgctc caacaactcg taaatggttt
    10861 gattctaggt agtgtttacg cgctgttagc cctaggatat accatggttt acggaattat
    10921 caagctcatc aacttcgccc atggtgatat ttatatgatg ggagccttta tcggttattt
    10981 cttgatcaat tctttccaaa tgaatttctt tgtagcgctt attgtagcta tgctagtgac
    11041 agctattctt ggtgtcgtga ttgagtttct tgcttaccga cctttgcgcc actctactcg
    11101 tattgctgtt ttgattacgg ctattggggt ttctttccta ttggagtatg gaatggtcta
    11161 tctggttggt gccaataccc gtgccttccc tcaagcgatt caaacagttc gatatgattt
    11221 gggaccaatt agcttaacaa atgtgcagtt aatgattttg gccatttcct tgattttgat
    11281 gattttgtta caagtcattg tccaaaagac taagatgggg aaagccatgc gtgcagtatc
    11341 agtagatagc gacgcggcac aattgatggg gatcaatgta aaccgtacga ttagctttac
    11401 cttcgctttg ggttctgctc ttgcgggtgc ggctggtgtt ctgattgctc tttattataa
    11461 ctctcttgag cctttgatgg gggttactcc aggtcttaaa tctttcgttg ccgcagtact
    11521 tggtggtatc ggaattattc ctggtgcggc tcttggtggc tttgtgattg gtctattgga
    11581 aacctttgcg acagcctttg ggatgtcaga tttccgtgat gccattgttt atggaatctt
    11641 gttgttgatc ttgattgtcc gcccagctgg tatccttggt aagaatgtga aagagaaggt
    11701 gtaaacgatg aaggaaaatt taaaagttaa tattctatgg ttactccttt tgttagctgg
    11761 ctatagcttg attagtgtac tggtttcagt cggagtactt aatctattct atgtacagat
    11821 tttacaacaa attggaatta atattatttt ggctgttggt ctcaacttaa tcgttggttt
    11881 ttcaggacaa ttttcacttg gtcatgctgg tttcatggcg attggtgcct atgcagcagc
    11941 tattattggt tctaaatcac caacctacgg tgccttcttt ggagctatgc ttgtaggggc
    12001 tttgctttca ggagcagttg ccttacttgt cggcattcca accttgcgct tgaaggggga
    12061 ctatcttgcg gtagcaactc taggtgtttc tgaaattatc cgcatcttta tcatcaatgg
    12121 tggaagcctt acaaatggtg cggcaggtat cttagggatt cctaacttta caacttggca
    12181 aatggtttac ttctttgtcg tgattacaac cattgcaacc ttgaacttct tgcgtagccc
    12241 aattggtcgt tcaaccctct ctgttcgtga agatgaaatc gctgctgagt cagttggggt
    12301 taatacgact aaaattaaaa tcatcgcttt tgtctttggt gccattactg caagtattgc
    12361 tgggtcactt caggcaggat ttatcgggtc tgttgtaccg aaagattaca ccttcatcaa
    12421 ctcaatcaac gttttgatta ttgttgtatt tggtggactc ggttccatta caggtgcggt
    12481 tgtttcggct attgttctgg gaattttgaa tatgcttctc caagatgttg ctagtgtgcg
    12541 tatgattatt tacgctttgg ccttggtatt ggtaatgatt ttcagaccag gtggactcct
    12601 tggaacgtgg gaactgagcc tatcacgttt ctttaaaaaa tctaagaagg aggaacaaaa
    12661 ctaatggcat tacttgaagt aaaacagtta accaaacatt ttggtggtct aacagctgtt
    12721 ggagatgtga ctcttgaatt gaacgaaggg gaactggttg gattaatcgg tccaaacgga
    12781 gctgggaaaa ccaccctttt caaccttttg accggtgttt atgaaccaag cgagggaaca
    12841 gtaaccctag atggtcacct tttgaatggg aaatcacctt ataagattgc ctctttggga
    12901 cttggacgta ctttccaaaa tatccgtctt tttaaagatt taacagtttt agacaatgtt
    12961 ttgattgctt ttggaaacca tcacaaacag catgttttta ctagtttctt acgcttacca
    13021 gttttttaca agagtgaaaa agaattaaag gctaaagctt tggaattgtt gaaaatcttt
    13081 gatttagatg gtgatgcaga gactcttgct aaaaatcttt cctacggaca acaacgtcgt
    13141 ttggaaattg ttcgtgccct tgctacggaa cctaaaattc tcttcttaga tgaaccagca
    13201 gcaggtatga acccacagga aacagccgaa ttgactgagt taattcgtcg tatcaaagat
    13261 gaatttaaga ttacaatcat gttgattgaa cacgatatga atctggtcat ggaagtaaca
    13321 gaacgtatct acgtacttga atatggccgt ttaattgctc aaggaactcc agacgaaatt
    13381 aagaccaata aacgcgttat cgaagcttat ctaggaggtg aagcctaatg tctatgttaa
    13441 aagttgaaaa tctttctgtg cattacggta tgatccaagc agtccgtgat gtaagctttg
    13501 aagttaatga aggagaagtt gtttccctta tcggtgccaa tggtgcaggt aagacaacta
    13561 ttcttcgcac cttgtcaggt ttggttcgac caagttcagg aaagattgaa tttttaggtc
    13621 aagaaatcca aaaaatgcca gctcagaaaa tcgtggcagg tggtctttca caagttccag
    13681 aaggacgcca cgtctttcct ggcttgactg ttatggaaaa tcttgaaatg ggagctttct
    13741 taaagaaaaa tcgtgaagaa aatcaagcta acttgaagaa ggttttctca cgctttcctc
    13801 gtcttgaaga acggaagaac caagatgcag ctactctttc aggaggggaa caacaaatgc
    13861 ttgccatggg acgcgctctt atgtcaacac caaaacttct tcttttagat gaaccatcaa
    13921 tgggacttgc cccaatcttc atccaagaga tttttgatat cattcaagat attcagaagc
    13981 agggaacaac cgtcctcttg attgaacaaa atgccaataa agcacttgca atctctgacc
    14041 gaggatatgt attggaaaca ggaaaaatcg tcctatcagg gacaggaaaa gaactcgctt
    14101 catcagaaga agtcagaaaa gcatatctag gtggctaaaa caatccagag gattgtttta
    14161 gccggcagat ggagattacg aagtaatcat caatatagtc cgggggacct ttttagtcgg
    14221 tagattgaga ttgcaaacaa atatgcatct acattgaaag cttaatttct aataattgaa
    14281 aaaatcgaat gaaaaatttc ttaccttcat tcacagagct ctatttcaga gctctttttg
    14341 ctagcttatt catacttttc tgaatttcga aaaagaaatg taagcgtttg atagatttgc
    14401 aaaaagattg tataataggg ataagaatag aaaaggagaa gtctcatggc agttaaagat
    14461 tttatgaccc gcaaggtagt ttatattagt ccagatacaa cagtatctca tgcagcagat
    14521 ttgatgagag agcaaggttt gcaccgtctg cctgttatcg aaaatgatca attagttggt
    14581 ttggtgactg agggaaccat tgcacaagca agtccatcta aagcaacaag tctttctatc
    14641 tatgagatga attatcttct gaataagaca aaagtaaaag atgtcatgat tcgcgatgtt
    14701 gtcactgtct caggctatgc tagtctagaa gatgcaactt atctgatgtt gaaaaataag
    14761 attagtattc tccctgtcgt agataaccat caagtatacg gagttattac tgaccgtgac
    14821 gttttccaag cctttcttga aattgcaggt tatggcgaag aagggattcg tgtacgcttt
    14881 gttacagaag atgaagttgg tgttcttgga aaaattgttt ctttgattgt agaagaaaat
    14941 ttgaatatct cccatacagt caatattccg cgtaaggatg gtaaggtgat tatcgaagtg
    15001 caaatcgatg gatcaattga tttaccagcc ttgaaagaaa aatttgaagc aaatggtatt
    15061 caagtggaag aaatcgctcg cacttcagca aaagtcttgt aagaagggaa gcccaaaggc
    15121 ttcttttttc atgaaaaggg gattagagaa aaagatggaa agaaatgata aaatatgcta
    15181 taatgaaata atgtaaaaaa ggagtattta tggacatttc agtaattcgt cagaaaattg
    15241 acgcaaatcg tgaaaaatta gcttctttca gggggtctct ttgacctcga agggctagag
    15301 gaagagattg ccatcttgga aaacaagatg acagaacctg atttttggaa cgataatatt
    15361 gcggcccaaa aaacgtcgca agaattaaat gaattaaaaa acacttacaa taccttccat
    15421 aagatggaag agttgcagga tgaagtcgaa attttattgg attttttggc tgaagacgag
    15481 tcagtgcatg atgaactggt agcgcagtta gccgaacttg ataagataat gaccagctac
    15541 gagatgactc tactcttgtc agaaccttat gaccacaaca atgccatctt ggaaatccat
    15601 ccaggttctg gtggtactga ggcgcaggac tggggtgata tgttgcttcg tatgtatact
    15661 cgttatggta atgctaaagg ctttaaagtg gaagtgttgg attaccaagc aggtgatgag
    15721 gctggtatta agtcggtaac tttatcattt gaagggccta atgcctatgg tctcctcaag
    15781 tcagaaatgg gtgttcatcg cttagtgcga atctcaccat ttgactctgc caaacgtcgc
    15841 catacctctt tcacatctgt agaagtgatg ccagaattgg atgatactat tgaagtggaa
    15901 atccgtgaag atgatatcaa gatggatacc ttccgttcag gtggtgccgg tggacaaaac
    15961 gtcaataaag tttcaacagg tgtacgttta acccacattc caactggaat tgttgtccaa
    16021 tcaacagtgg atcgtaccca gtatggaaat agagatcgtg ccatgaagat gttgcaggct
    16081 aagctctatc aaatggagca agataagaag gctgcggagg tagattctct caaaggtgag
    16141 aaaaaggaga tcacttgggg aagccaaatc cgttcttatg tcttcacgcc ttatactatg
    16201 gtaaaagatc accgaactag ctttgaggtt gctcaggtag ataaggttat ggatggggac
    16261 ctagatggtt ttatcgatgc ttatctcaag tggcgaatta gctaagatag aaaggaactc
    16321 acatgtcaat tattgaaatg agagatgtcg ttaaaaaata cgacaacgga acgactgctc
    16381 tacgcggtgt ttcggtcagc gttcaaccgg gggaatttgc ttacatcgta ggaccttcag
    16441 gagcagggaa gtcaactttt attcgttctc tgtatcgtga agtaaaaatc gataaaggaa
    16501 gcctatcagt tgctggtttt aatctggtta agatcaaaaa gaaagatgtc ccgcttctac
    16561 gtcgtagtgt tggggttgtc ttccaggatt ataaattgtt accaaagaaa actgtctatg
    16621 aaaatattgc ttacgctatg gaagtaatcg gggaaaatcg ccgtaatatc aaaaaacgag
    16681 tgatggaagt tttggacttg gttggattga agcataaggt tcgttctttc ccaaatgaac
    16741 tctcaggtgg ggagcaacag cggattgcga ttgcgcgtgc aattgtaaat aatcccaaag
    16801 tattgatagc tgatgagcca acaggaaatc tggatccgga taattcatgg gaaattatga
    16861 atctcttgga acggattaac ctacaaggga caactatttt gatggcgact cataatagcc
    16921 agattgtaaa taccttgcgc caccgtgtca ttgccattga aaatggccgt gtcgttcgtg
    16981 acgaatcaaa aggagagtat ggatacgatg attagtagat tttttcgcca tttatttgaa
    17041 gccttaaaaa gtttgaaacg aaatggttgg atgacagtag ctgctgtcag ttcagtcatg
    17101 attactttga ccttggtggc aatatttgca tctgttattt tcaatacagc gaaactagct
    17161 acagatattg aaaataatgt ccgtgtagta gtttatatcc gaaaggatgt ggaagataat
    17221 agtcagacaa ttgaaaaaga aggtcaaact gttacaaata atgactacca caaggtatat
    17281 gattctttga agaacatgtc tacggttaaa agtgttacct tttcaagtaa agaagaacaa
    17341 tatgaaaaat taaccgagat aatgggagat aactggaaaa tctttgaagg agatgccaat
    17401 cctctctatg atgcctatat tgtagaggca aacgctccaa atgatgtaaa aactatagcc
    17461 gaagatgcta aaaaaattga aggtgtctct gaggttcaag atggcggtgc caatacagaa
    17521 agactcttca agttagcttc atttatccgt gtttggggac tagggattgc tgctttgtta
    17581 atttttatcg cagttttctt gatttcaaat accattcgta ttaccattat ttcccgcagt
    17641 cgcgaaattc aaatcatgcg cttggtcgga gctaaaaaca gttatatccg tggaccgttc
    17701 ttgttagaag gagcctttat cggtttattg ggagctatcg caccatctgt tttggtcttt
    17761 attgtttatc aaattgttta ccaatctgtc aacaaatcgt tggtagggca aaatctatcc
    17821 atgattagtc cagatttatt tagtccgttg atgattgccc tactatttgt gattggggtt
    17881 ttcattggtt cattgggatc aggaatatcc atgcgccgat tcttgaagat ttaggtaaaa
    17941 tagctgcttt tatgaggaga ttgtaaaatc tccttttttg ctacaagagt ttttgaaaag
    18001 agatgcgtag aagaaaagag cttccaaaga agtcccccag agaagacttc ttgatggcta
    18061 atttgaactt gaaatttggc gcactagaaa ttttttagaa aaaagtgtaa tttttttata
    18121 aaagccttta caaaaaaaat taaagtggta taattaaatc atagaaggtg caaacgtttt
    18181 cgtaaaacgt ttgcctaaat aaaaataaag gagatttgaa tgatgaaaga tacattcaaa
    18241 aatgtcttgt ctttcgaatt ttggcaaaaa ttcggtaagg ctttgatggt agttatcgcg
    18301 gttatgccgg ctgctggttt gatgatttca atcggtaagt ctatcgtgat gattaaccca
    18361 acctttacac cacttgtcat cacaggtgga attcttgagc aaatcggttg gggggttatc
    18421 ggtaaccttc acattttgtt tgccctagcc attggaggaa gctgggctaa agaacgtgct
    18481 ggtggtgctt tcgccgctgg tcttgccttt atcttgatta accgtatcac tggtacaatc
    18541 tttggtgtgt caggcgatat gttgaaaaat ccagatgcta tggtaactac tttctttggt
    18601 ggttcaatca aagttgctga ttactttatc agtgttcttg aagctccagc cttgaacatg
    18661 ggggtattcg tagggattat ctcaggtttt gtaggggcaa ctgcttacaa caaatactac
    18721 aacttccgta aacttcctga tgcactttca ttcttcaacg ggaaacgttt cgtaccattt
    18781 gtagttattc ttcgttcagc aatcgctgca attctacttg ctgctttctg gccagtagtt
    18841 caaacaggta tcaataactt cggtatctgg attgccaact cacaagaaac tgctccaatt
    18901 cttgcaccat tcttgtatgg tactttggaa cgtttgctct tgccatttgg tcttcaccac
    18961 atgttgacta tcccaatgaa ctacacagct cttggtggta cttatgacat tttaactggt
    19021 gcagctaaag gtactcaagt attcggtcaa gacccactat ggcttgcatg ggtaacagac
    19081 cttgtaaacc ttaaaggtac tgatgctagt caataccaac acttgttaga tacagtacat
    19141 ccagctcgtt tcaaagttgg acaaatgatc ggttcattcg gtatcttgat gggtgtgatt
    19201 gttgctatct accgtaatgt tgatgctgac aagaaacata aatacaaagg tatgatgatt
    19261 gcaacagctc ttgcaacatt cttgacaggg gttactgaac caatcgaata catgttcatg
    19321 ttcatcgcaa cacctatgta tcttgtttac tcacttgttc aaggtgctgc cttcgctatg
    19381 gctgacgtcg taaacctacg tatgcactca ttcggttcaa tcgagttctt gactcgtaca
    19441 cctattgcaa tcagtgctgg tattggtatg gatatcgtta acttcgtttg ggtaactgtt
    19501 ctctttgctg taatcatgta ctttatcgca aacttcatga ttcaaaaatt caactacgca
    19561 actccagggc gcaacggaaa ctacgaaact gctgaaggtt cagaagaaac cagcagcgaa
    19621 gtgaaagttg cagcaggctc tcaagctgta aacattatca accttcttgg tggacgtgta
    19681 aacatcgttg atgttgatgc atgtatgact cgtcttcgtg taactgttaa agatgcagat
    19741 aaagtaggaa atgcagagca atggaaagca gaaggagcta tgggtcttgt gatgaaagga
    19801 caaggggttc aagctatcta cggtccaaaa gctgacattt tgaaatctga tatccaagat
    19861 atccttgatt caggtgaaat cattcctgaa actcttccaa gccaaatgac tgaagcacaa
    19921 caaaacactg ttcacttcaa agatcttact gaggaagttt actcagtagc agacggtcaa
    19981 gttgttgctt tggaacaagt aaaggatcca gtatttgctc aaaaaatgat gggtgatgga
    20041 tttgcagtag aacctgcaaa tggaaacatt gtatctccag tttcaggtac tgtatcaagc
    20101 atcttcccaa caaaacatgc ttttggtatt gtgacggaag caggtcttga agtattggtt
    20161 cacattggtt tggacacagt aagtcttgaa ggtaaaccat ttacagttca tgttgctgaa
    20221 ggacaaaaag ttgcagcagg agatctcctt gtcacagctg acttggatgc tatccgtgca
    20281 gcaggacgtg aaacttcaac agtagttgtc ttcacaaatg gtgatgcaat taaatcagtt
    20341 aaattagaaa aaacaggttc tcttgcagct aaaacagcag ttgctaaagt agaattgtaa
    20401 tatacttgag gttggaagct gtattccaac ctcttatttt gggagaaaag aatgaaattt
    20461 ttaacactca atactcacag ttggatggag aaagaagcag aggaaaaatt ccagattttg
    20521 cttgaagata ttcttgaaaa ggactatgat ttgatttgtt tccaagaaat caatcaggag
    20581 atgacctcgt cagaggtgga ggttaatgac ctttatcaag ctttgccagc agctgagcct
    20641 attcaccaag accattatgt tagactcttg gttgaaaagt tgttagagca agggaaaaat
    20701 tactactgga cctgggctta taaccatatc ggctatgacc gctaccatga aggtgtggct
    20761 atcttgtcta aaacacctat tgaagccaga gaaattttgg tttcagatgt ggatgatcca
    20821 acagactatc atactcgccg tgttgcccta gctgaaactg tagtcgatgg caaggagcta
    20881 gcagttgcca gtgttcatct ctcttggtgg gataaaggtt tccaagaaga atgggcacga
    20941 tttgaggctg tcttgaaaaa attgaacaag ccacttttac tagctggaga ttttaacaac
    21001 ccagcaggtc aggaaggtta ccaagctatt ttagctagtc cattaggctt acaagacgca
    21061 tttgaagttg ctcaagagaa aagtggtagc tatactgttc cgcctgaaat tgatggctgg
    21121 aaagggaaca ctgaacccct tcgaatcgat tatgtcttta ctaccaaaga gttagcggtg
    21181 gaaaatttac atgtcgtatt tgatggtaac aagagtccac aagtgagtga tcactatggc
    21241 ttgaatgcgg tattaaattg gaaataaaat caaaaaatga aagggagcga gtcctttcat
    21301 ttttttacaa aaatccctat aattactatt ttggagaagg agttttttgt atatttgtat
    21361 attatgagga aatatccaca aataagtttt taaaacttta cggtcaaaaa aaaatcgcta
    21421 atattaacta tttatgatag aatgaaaatt atgaaataaa aggaggactg gaatgttttt
    21481 tcaggataga aagataaaat attcaatccg caaattgtca gttgctactg tgtcccttgc
    21541 gattggattt ttgtttgcgc ctgcggcgct tggagtcgct caagtagctc aagctgatga
    21601 gctttcaact actgaacaag tggagaataa agcagagaat caggtctcgg tggtctcttt
    21661 tgcaacagag caagaagaaa gtgaaacgac ttatgttgat acgacgaata aagtgacttg
    21721 gacatttgca ggatacgata aagaaaaaat tgttgtagga aaaggcagac agactttcct
    21781 tggaagctgg gtacctactc caaatccaga atatgtattc aaatcatcta aagcaggtgt
    21841 tccattacca caaagtattt tgggaatgct tccaaaggat gaagcttctt ataaggttgg
    21901 tgacaccatt gtagccaaac aacctgctgt agaatcagta gtcgaagaag aaaaagacta
    21961 tgtctggacc ttcaaaggtt atgatcagaa gaatgcgacg tacaatggca agcgtgtgac
    22021 atttacaggt atctgggaag taacgcctag accgcatcat gtaagctata cttttgtaag
    22081 tgttacatct ggtgttgatt tgcctaaatt tatccagaag aaagcaccaa aagatggctc
    22141 aacttacttc aataggacga gagtttttgc agaagagccg acaacaaaga cctacataga
    22201 tagtgtgaac gatggcacat ggaccttcaa gggttatgac gcagctagcg ccgttgttaa
    22261 caaggctaat gtagagtttg taggtaagtg ggaattcaag g
//
LOCUS       DAVMCN010000027        22125 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVMCN010000027 DAVMCN010000000
VERSION     DAVMCN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22125
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.027"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(79..1098)
                     /gene="adhP"
                     /locus_tag="VYP85_001239"
     CDS             complement(79..1098)
                     /gene="adhP"
                     /locus_tag="VYP85_001239"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1881760.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1437..2249)
                     /locus_tag="VYP85_001240"
     CDS             complement(1437..2249)
                     /locus_tag="VYP85_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1881761.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2439..3857
                     /locus_tag="VYP85_001241"
     CDS             2439..3857
                     /locus_tag="VYP85_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1881762.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTDEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            3910..4617
                     /locus_tag="VYP85_001242"
     CDS             3910..4617
                     /locus_tag="VYP85_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1881763.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            4712..5686
                     /gene="folP"
                     /locus_tag="VYP85_001243"
     CDS             4712..5686
                     /gene="folP"
                     /locus_tag="VYP85_001243"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1881764.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGKFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5688..7010
                     /locus_tag="VYP85_001244"
     CDS             5688..7010
                     /locus_tag="VYP85_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1881765.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            6991..7545
                     /gene="folE"
                     /locus_tag="VYP85_001245"
     CDS             6991..7545
                     /gene="folE"
                     /locus_tag="VYP85_001245"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1881766.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7588..8400
                     /gene="folK"
                     /locus_tag="VYP85_001246"
     CDS             7588..8400
                     /gene="folK"
                     /locus_tag="VYP85_001246"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1881767.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8550..8867)
                     /locus_tag="VYP85_001247"
     CDS             complement(8550..8867)
                     /locus_tag="VYP85_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1881768.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9224..9670
                     /gene="rplM"
                     /locus_tag="VYP85_001248"
     CDS             9224..9670
                     /gene="rplM"
                     /locus_tag="VYP85_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1881769.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9689..10081
                     /gene="rpsI"
                     /locus_tag="VYP85_001249"
     CDS             9689..10081
                     /gene="rpsI"
                     /locus_tag="VYP85_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1881770.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10342..10764)
                     /locus_tag="VYP85_001250"
     CDS             complement(10342..10764)
                     /locus_tag="VYP85_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1881771.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            10911..11087
                     /locus_tag="VYP85_001251"
     CDS             10911..11087
                     /locus_tag="VYP85_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881772.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            11488..13701
                     /locus_tag="VYP85_001252"
     CDS             11488..13701
                     /locus_tag="VYP85_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1881773.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSIPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(13923..14399)
                     /locus_tag="VYP85_001253"
     CDS             complement(13923..14399)
                     /locus_tag="VYP85_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1881774.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            14622..17825
                     /locus_tag="VYP85_001254"
     CDS             14622..17825
                     /locus_tag="VYP85_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1881775.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIIGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFNNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESGNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            18178..18564
                     /gene="tnpA"
                     /locus_tag="VYP85_001255"
                     /pseudo
     CDS             18178..18564
                     /gene="tnpA"
                     /locus_tag="VYP85_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557980.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(18940..19569)
                     /locus_tag="VYP85_001256"
     CDS             complement(18940..19569)
                     /locus_tag="VYP85_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1881776.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISKIAQQYVTLR"
     gene            complement(19579..20580)
                     /locus_tag="VYP85_001257"
     CDS             complement(19579..20580)
                     /locus_tag="VYP85_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1881777.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(20611..21252)
                     /locus_tag="VYP85_001258"
     CDS             complement(20611..21252)
                     /locus_tag="VYP85_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1881778.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEIAAYLKEVLAK"
     gene            complement(21271..22086)
                     /locus_tag="VYP85_001259"
     CDS             complement(21271..22086)
                     /locus_tag="VYP85_001259"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1881779.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRIPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6637 a         4052 c         4867 g         6569 t
ORIGIN      
        1 aatcttgaat tcttatttaa aatttaatat aaaaaagttg gaagaagctt ccaactttta
       61 aaataggttt ctattagatt agtgggtgaa gtcgagtacc atacgtcctt ggatttggcc
      121 tttttccatt tcgtcgaaaa tggcaacagc atcttctact ggacgttttt gaacaactgg
      181 gactaccaga ccttctgcac caaattggaa ggcttcttct aagtctttac gagttccgac
      241 aagagaaccg atgacttgga ttccatcgag gactgtttta acgatgctga gttccatcgt
      301 ttcagaagga agaccaacag cgacgacgcg accaccagca cgaatggagt caacagcctg
      361 gttgaaggca actttagaca cagcagttac gacagctgaa tgagctcctc catcagtttt
      421 ttctttaatg agtccagcta catcttcaac ttcgaggccg ttaatcacaa tgtcagcgcc
      481 tacttctttt gcaagggcaa gtttgtcatt gttgatatcg actgcgataa catgagcatt
      541 gaatactttt ttagcgtatt gaacagcgag gttaccaagt ccaccagcac cgtaaagaac
      601 aacccattgg cctggttcaa cttttgcttc tttgatagct ttataggttg ttactccagc
      661 acatgtgata gaagaagctt gggctggatc aagtccgtca ggaactttga cagcatagtc
      721 agcagttacg atacattgtt cagccatacc accgtctact gagtagccag catttttcac
      781 tgtacggcaa agggtttcgc gaccagttgt acagtattcg caagtgccac atccttcaaa
      841 gaaccaagca acgctgacgc ggtcaccgac tttaaggctt ttcacatctg gagcaatctc
      901 tttaacgata ccgatacctt cgtgcccaag aacacgtcct gggacttgac caaagtcacc
      961 atgagcaacg tggaggtcgg tgtggcaaac accacagtat tcaacttcta caagtgcttc
     1021 cccagtttca agtggacgga gtactttttc ttcaatagca acaccagtgc tttctggatt
     1081 tacaacaaca gctttcatag ctatcctcct tgatattgac cgagaacagg gacaacggga
     1141 ctggattgat tttttgtcaa cagagtcgag tgtgacgagc tctcttgtat ttatatgtga
     1201 agtatatcac aaaagaaagc cttttccaag gttttggaga caaaaagtag aacaatcgat
     1261 taactggttg atgagactgt gaaaagagca caaagaccag cttgcaagct ggtcatactc
     1321 ttcgaaaatc tcttcaaacc acgtcagctt catctacaac ctcaaagcag tgctttgagc
     1381 aacctacggc tagcttccta gtttgctctt tgattctcat tgagtatcag tataggttat
     1441 aagaataagt cttgtagggt tttggcaacc ccatcttggt cgttggtaag ggaaatttgc
     1501 tcatctgcat aagggagtag ctctggattg gcatttttca tggcataacc cttcccagca
     1561 aaagcgagca tttcggtatc attgtgttca tctccaaagg caatcaaatc ttttttgtca
     1621 cgattcatta tcttgagcaa gtagtccaaa gcaaaggcct tgttgacacc ttttggggta
     1681 cattcaagga tattgagcgg acctccccag gtattgatag aaagttgatg ctggtagaag
     1741 gcgttcattt cttttgccaa ggcatatttg tcactggctc tggtctgcaa gaggatacag
     1801 ttagggtcct tggtcaccaa ttcaggctgg aattgatctt caggctggaa agcttctaca
     1861 ccaaatagtt tgggattggc aatttcttca ttgggatttg taatgtagaa ttttttacga
     1921 tattctccag cgataaaatc ggcttgaatg tcctctgaac gttgaaccat atctagcaga
     1981 tattttttgt ctacagtcaa acacttttca aaatcccaaa cttggtctgg taaatgagta
     2041 agggatccgt tgaagttaat cataggagtg tctaagccca gttcacggta aaaatctttt
     2101 gacatacggt aagggcgacc tgtcgtaata ataacctgat ggcctttttc agcaactttt
     2161 ttgatggttc ttttggtaaa gtcagaaatt tgactgtctg agttgagcag ggttccatcc
     2221 aggtcaactg caataatttt tttcgtcata tggacctttc tagtgtgttt tcagataaga
     2281 tgtcttctat tataacagaa agcaggcaga aaagcagatt ccaaacaaaa aatgaaattg
     2341 gattaatttc ttaaacaaat caaacaaaga cattgaaaaa gtgaatgata aatgatataa
     2401 ttctattatt gttcgtaaaa attaaaagga gattgatgat ggacaaatta tttaaactaa
     2461 aagagaacgg tacagacgtt cgtacagagg ttctcgctgg tttaacaact ttctttgcaa
     2521 tgagctatat tctctttgta aacccacaaa tactttcaca aacaggaatg cctgctcagg
     2581 gcgtcttcct agcgacgatt attggtgcag tagcgggtac cttgatgatg gctttttatg
     2641 ctaacttacc ttatgcccaa gcgccaggta tgggactcaa tgccttcttt acctttacag
     2701 ttgtattcgg gcttggttat tcttggcaag aagccctagc tatggtcttc atctgtggga
     2761 ttatttcatt gattattacc ttgacaaatg ttcgtaaaat gatcattgaa tcgattccca
     2821 atgctcttcg ctcagctatt tcagctggta tcggtgtctt ccttgcctat gtagggatta
     2881 agaatgctgg acttttgaaa ttcacgattg atccaggcaa ctatactgtt gtaggagaag
     2941 gggctgacaa agctcaagca acgattgcag caaactcttc agcagttcca ggattggtca
     3001 gctttaataa tccagctgtt ttagtggctc ttgcaggact tgccattact atcttctttg
     3061 tcatcaaagg gattaaaggg ggaattattc tctctatctt gacaacaact gttcttgcta
     3121 ttgcagttgg tttggttgat ttgtctagta tcgattttgc taataaccat gttggtgcag
     3181 cttttgaaga tttgaagaca atctttggtg cagctcttgg ttcagaagga ttgggagctt
     3241 tggtttcaga tacagctcgc ttgcctgaaa ctctgatggc cattcttgcc ttctcattga
     3301 cagatatttt tgacacaatt ggtaccttga tcggtacaga tgaaaaagtt ggtattgtag
     3361 cgacaaatgg tgaaaatcac caatcagcca aattggataa ggctctttac tctgatttga
     3421 ttggaacgac agtcggtgcc attgcaggta cttcaaacgt aacgacttat gttgagtctg
     3481 ctgctggtat cggtgcaggt ggacgtactg gtttgacagc cttggttgta gctatctgtt
     3541 ttgcgatttc aagcttcttt agcccacttc tagcgatcgt accaacagcg gctacagctc
     3601 caatcttgat tatcgttggg attatgatgc ttggtagctt gaaaaatatc cattgggatg
     3661 atatgtctga agcagttcct gccttcttca catctatctt tatgggattc agctactcta
     3721 tcactcaagg gattgcagtt ggtttcttga cttacacttt gactaagctt gtcaaaggtc
     3781 aagttaaaga tgttcatgcc atgatttgga ttttggatgc cttgtttatc cttaactaca
     3841 tcagcatggc cttataatag aatgacccag ggggatttcc cccctttttt aatacaaagg
     3901 agataggtga tgaaagagaa aaatatgtgg aaagaattgt tgaatcgtgc aggctggatt
     3961 ttggtctttt tacttgccgt ccttttatat caggttcccc tagtggttac ctctattttg
     4021 actttaaaag aagtagccct gctacagtca gggctgatag ttgctggcct ttcaattgtg
     4081 gttctggctc tatttattat gggagctcgt aaaaccaagt tagctagttt taatttttct
     4141 ttttttagag ctaaagattt ggcacgtttg ggcttgagtt atttagttat tgtcgggtca
     4201 aatatacttg gttctatctt gttgcaactg tcaaatgaga cgacaacagc taaccagtct
     4261 cagattaacg atatggttca aaatagttcg ttgatttcca gtttcttctt gctagccttg
     4321 cttgctccaa tttgtgagga aatcttgtgc cgtgggattg ttcctaaaaa gattttccga
     4381 ggcaaggaga acttgggatt tgtagtcggt acgattgtgt ttgctttatt gcatcaacca
     4441 agtaatttac cttctttatt gatttatgga ggtatgtcga cagttctatc ttggacggcc
     4501 tacaagaccc aacgtttgga aatgtcgatc ttgcttcaca tgattgttaa tgggattgct
     4561 ttctgtttgt tggctcttgt ggtgattatg agtcggacat taggaatttc tgtgtaaaag
     4621 tttttatgta ggaaccgacc tctttctact agggaaagat gaatgcaatc gtgtccatct
     4681 ttttcttttt atggtaaaat agaaaaataa tatgatgaaa atccttgagg gagtgaccga
     4741 tatgtcaagt aaagccaatc atgcaaagac agttatttgc ggaattatca atgtaacccc
     4801 agactccttt tcggacggtg gtaaattttt tgctcttgag caggcactcc agcaggctcg
     4861 taaattgata gcagaaggag ccagtatgct cgatatcggc ggagaatcga ctcggccggg
     4921 cagtagctat gttgagatag aagaggaaat ccagcgtgtt gttccagtga tcaaagcgat
     4981 tcgcaaggaa agtgatgtcc tcatctctat tgatacttgg aagagtcaag tagcagaggc
     5041 tgctttggct gctggtgccg atctagtcaa tgatatcact ggtcttatgg gtgatgagaa
     5101 aatggctcat gtggtagctg aagcgagagc gcaagtggtc atcatgttta atccagttat
     5161 ggcgcgacct cagcacccta gctcgctcat cttccctcat tttggttttg gtcaagcttt
     5221 tacagaggaa gagttagctg actttgaaac attgccaatc gaagacttga tggtggcttt
     5281 ctttgaacga gcactagcga gagcggcaga agctggtatt gcaccagaaa atatcctgtt
     5341 ggatccagga attggctttg gtctgaccaa gaaagaaaat ctcctccttt tacgggatct
     5401 ggataaacta catcagaagg gctatccaat ctttctcgga gtgtcgcgca agcgatttgt
     5461 catcaatatc cttgaagaaa gtgggtttga agtcaatcct gagacagagc ttggtttccg
     5521 aaatcgggac acggcttcgg ctcatgtaac tagtatcgct gcgagacagg gtgtagaagt
     5581 ggtgcgcgtg catgacgtag ctagtcacag gatggcagtt gaaattgcat ctgccattcg
     5641 tctggctgat gaagcggaaa atttagattt aaagcaatat aaataagatg aaagaaattg
     5701 aaaacaatca gtggattgct aactaccgga cggatcaacc gcattttggc ttggaacgaa
     5761 tggtggaact gttagctttg cgtggcaatc cccatctcaa actcaaggtc ctccatatcg
     5821 gagggactaa cggcaagggc tcgactattg cttttttgaa aaagatgcta gaaaagctag
     5881 ggctgagagt tggcgtgttt agctcgccct atctcattca ttacacagac cagattagca
     5941 tcaatgggga atcgatctca gaagcgaggc tagaagctct catggcagac tatcagtctt
     6001 tgctggaggg agaagcggtc gccaatttac agggcacaac cgagtttgag attatcacag
     6061 ccctggccta tgactacttt gcctcagagc aagtagatgt ggccatcatg gaagttggca
     6121 tgggtggact tttggatagt accaatgtct gtcagcccat tttgacagga attacaacta
     6181 ttggcttgga tcatgtggcc ctacttggtg acaccttgga ggccatagca gagcagaagg
     6241 caggtattat caaacaaggg atgcccttgg taacagggcg tattgctcca gaagccttga
     6301 ctgtgattga ccgcattgcg gaagggaaag attcgccgag acttgcctac gggacagatt
     6361 atcaggttcg tcatcaagaa agtgtggtga caggggaagt ctttgactat acaagtgctg
     6421 tcagacaagg tcgcttccag actagcctgc ttggtttgta ccaaatagag aatgctggga
     6481 tggccatagc tttacttgat actttttgtc aagaagatgg tcgagagcta gcaagcaatg
     6541 actttcttgg tcaagccttg gaagaaacaa gttggccagg gcgtttggaa atcgtgtcaa
     6601 gagatccctt gatgattttg gatggagccc acaatcccca tgctatcaag gccttgttgg
     6661 taaccttgca agaacgtttt gcggattatc ataaggaaat cctcttcact tgtatcaaaa
     6721 ccaaggcctt ggaggatatg ttggacttgc tgggagccat gccagatacc gagcttactc
     6781 taacacattt tgcggatagt cgggcgacgg atgaaagcgt gctgaaagag gcagctaagt
     6841 ctagaaatct cagctaccaa gattggcatg attttctaga gcagaatttg acagataaaa
     6901 aagaagagaa acaaacagtt aggattgtca caggttcctt gtatttcttg agccaagtga
     6961 gggcctatct gatggagagg aagaacgaga atggatacac aaaagattga agcagctgta
     7021 aaaatgatta tcgaggctgt aggagaggac gctaatcgcg agggtttgca ggaaacacct
     7081 gctcgtgtag cccgtatgta tcaagagatt ttttcaggtc ttggtcaaac agcagaggaa
     7141 catttgtcaa aatcctttga aattattgac gataatatgg tggtagaaaa ggatatcttt
     7201 ttccatacca tgtgtgaaca ccacttcttg ccattttatg gtagagcgca cattgcctac
     7261 attccagatg gtcgtgtggc aggcttgtct aagctagccc gtacggttga agtttattcg
     7321 aaaaaaccac aaattcaaga acgtttgaat atcgaagtgg ccgatgcctt gatggactat
     7381 ctaggtgcta aaggagcctt tgttatcatt gaggcggaac atatgtgtat gagtatgcgt
     7441 ggtgttagaa aaccaggcac tgcaaccttg acgacagtag ctcgtggtct atttgaaaca
     7501 gataaggacc tccgcgacca agcttatcgt ttaatggggc tataaaaaga atccgtttca
     7561 agcggatttt tctagaaagg aatcattatg gatcaactgc agattaagga tttggaaatg
     7621 tttgcctatc atggtctttt tcctagtgag aaagaattgg ggcagaaatt tgtcgtttca
     7681 gccatcctat cctatgatat gaccaaggca gctacagact tggatttaac agcctctgtc
     7741 cattacggag aattgtgtca gcagtggacg acttggtttc aggaaacgag tgaagatttg
     7801 attgaaacgg tagcctataa actggtggaa cgtacctttg agtcttatcc tcttgtccaa
     7861 gaaatgaagt tggaactgaa aaaaccttgg gcaccggtgc atttgtcact agatacttgc
     7921 tcggtaacca ttcatcgccg caagcaacga gcctttatcg ccctaggaag caatatggga
     7981 gataagcaag caaacttgaa gcaagccatt gacaaactgc gagctcgtgg catccatatt
     8041 ctcaaagagt ccagtgtctt agcgacggag ccttggggtg gagtggagca ggatagtttt
     8101 gccaatcaag tggttgaggt ggaaacctgg ctaccagcac aagacttgtt agaaaccttg
     8161 ttagccattg agtcagagct gggacgggtg agagaagtgc attggggacc tcgtttgatt
     8221 gatttggact tgctctttgt ggaggaccag atcctttata cagacgacct catattgcct
     8281 catccctaca tagcggaacg cctttttgtc cttgagtcct tacaggaaat tgcgcctcat
     8341 tttatccatc cgatattaaa acaaccgatc cgcaacttgt atgatgcttt gaaaaaatag
     8401 aaaaactcta gttttcagtc acttgcaact gaaggctaga gtttttatac tcttcgaaaa
     8461 tctcttcaaa ccacgtcagc gtcgccttac cgtactcaag tacagcttgc ggctagcttc
     8521 ctagtttgct ctttgatttt cattgagtat taaaataggt cattttcttc tgggaggagg
     8581 atagtttctc taccgtccat gtctaaaacc agtactcttg ggggataacg agggtcgaaa
     8641 ggatggttaa agtcaaaatc aatggctgta gggaggtgtt gacttgaaaa gtggaaggta
     8701 atctttcctt ggttattaag caattgaaac tcgagttctt cttccaattc aaagacattt
     8761 tttaagaaat ggtcgataat ataccaaaaa gagtcaatga tgtcatcagg caagctggta
     8821 acaatgccaa aactagcaga ccgcatgtga gtattggtaa aagccatatc tctgtcccct
     8881 ttcttttccc ttatcataca gcaaatagga ttaaaaatca agaaaaggtg attttttgaa
     8941 aaggatttta actacaggga aaaagaagga aaaaaattcc caaaaatcta ccgaagttaa
     9001 taggtaaatt cccaaattaa cttgattata taactttcag ttactttgag aagttaccga
     9061 aaaatatttt tcatatctat tgacttttag gggtgaaatt tggtatgata gtaggcggta
     9121 ttgtttaccc catttgaaag gccccggaac cttccaaata cttttcgatg ggaaggaaca
     9181 cccatcaccg taaacaaaaa tcgaactata tataggagaa atcatgaaca aaacaacatt
     9241 tatggctaaa ccaggccaag ttgaacgtaa atggtacgta gttgacgcaa ctgatgtacc
     9301 acttggacgt ctttctgcag tagttgctag cgtacttcgc ggaaaaaaca aaccaacatt
     9361 tacaccacac actgatacag gtgacttcgt gattgttatc aatgctgaaa aagttaaatt
     9421 gactggtaaa aaagcaactg ataaaatcta ctacactcac tcaaaccacc caggtggatt
     9481 gaaacaaatc tctgcaggtg aacttcgttc taaaaatgca gtacgtttga ttgagaaatc
     9541 agttaaaggt atgcttccac acaatacact tggacgcgct caaggtatga agttgaaagt
     9601 atttgttgga gctgagcaca ctcacgctgc acaacaacca gaagttcttg acatttcagg
     9661 acttatctaa ggaaaggaac aataaagtat gtcacaagca caatatgcag gtactggacg
     9721 tcgtaaaaac gctgttgcac gcgttcgcct tgttccagga actggtaaaa tcactgttaa
     9781 caaaaaagat gttgaagagt acatcccaca cgctgacctt cgtcttgtca tcaaccaacc
     9841 attcgcagtt acttcaactg taggttcata cgacgttttc gttaacgttg taggtggtgg
     9901 atacgctggt caatcaggag ctatccgtca cggtatcgct cgtgcccttc ttcaagtaga
     9961 cccagacttc cgcgattcat tgaaacgcgc aggacttctt acacgtgact cacgtaaagt
    10021 tgaacgtaag aaaccaggtc ttaagaaagc tcgtaaagca tcacaattta gtaaacgtta
    10081 attcgaaaga attactatac ttatacagag cacctttcgg ggtgttcttt tttatacttt
    10141 cttactaaat tggtgcaatt gacacagttg ttgcgacttt agtcgcttac aaatgtggct
    10201 gcaacctgac aaggtcagtt gcctcaaaac gttaatcaat acaattatat caacgtttca
    10261 aagcactcaa gagtttacct catgggtgct ttttttatgt tttttgaaaa agttcacctc
    10321 aaagtttacc ttattttcac cttattgttt tagagactgt aaggcaaatt caccgacggc
    10381 catagggact acattagaag tattgacata aatctgtgtt gtacctgtgt cgctatgtat
    10441 tagagcttca gaaatggctt ctaagctcat tcctgcttgt ttagcgagcg ttgctccggt
    10501 atgacgtagt ttgtgtggcg tagcgtgtgt aagctctggg tgtcgttttc tgatagtttt
    10561 catcttatta ttgagatagt cagaatgtaa aggtttattg atattgcctt tggtatctat
    10621 gtaagtaaag atgaattgtt ctggattact gatgatacca aactttgcca gttcatattt
    10681 ttgttgtttt ttccatgaag tcagaagttg aagtaagtca ttagaaatag agaaaatggg
    10741 aaatgtttcc acaataaaac gcatattatc agatggttaa tgcgttttat atttgggttt
    10801 gaggcttata aaataggata agcgtgctga aaacttagat atgacaaaca aaataaaatt
    10861 tttaaaagct acatagaaac atggtataat gtatctaaag gaggtagcat atgtccttag
    10921 atatagataa agaaaagatg acaatcatgg gaatagcttt tgaaaaccga tccgttttta
    10981 agagtgtttg gtatgcttta agtacaaata tgattgaagg atggcgacct acggttagtg
    11041 atgttgaaaa attacgagat gaagctcttg ctctggggat gacttaatga aacgcaactg
    11101 ttatgagtct tatgactatg ttgatcctga taatttatat accgatccgg gttcttcagt
    11161 tctaagaaat aagcaggaag gaaaaaagca cgtgagcttg aatatcgtat gattgctagt
    11221 aagagtttga aattatttat caatcctatc ttagttaata gtttaaaagt agtttgtttc
    11281 acaactgcat aagcttagaa aagttgaaaa gtgataactc tttaataaac tcttggtttg
    11341 ttaaaagata ttttgtccac tgcatttttt caattgacta ttatttgtca tagatataac
    11401 agatagaaca ttgcattcag aataatgaaa aacgcatcaa aaatggtgcg ttctgttttt
    11461 atgctaccat aaaaggagga aaacaaattg aaaattttta agggagagtt ttatcgaatc
    11521 tctgtattaa cagacaagct agtaaggtta gaatactctc gaactggaaa ttttgaggat
    11581 agaacgacac aacttatcta taatagagat tttggccaag tttcgttaga ttatatcgag
    11641 acatcaaatg tactagatat tatgacggac tattttcatc tgcactttaa taaaggagaa
    11701 tttaacgccg aaaatttatt tatagaatta aaaggaaatt ttgccgtata tggtagtcgc
    11761 tggtatttcg gtgaatctat tgaaacgtta aaaggaacag ctcggactct ggataaggca
    11821 gatggagcaa tctcgttaga agatggaatt attagccgaa atggtatagc cttattggat
    11881 gattctcaag gatttatttg ggatgaacaa tctggttata ttgagagaga aaatcaaatt
    11941 gacctgtatt tctttgccta tgggcatgat tatagaggag caatcagaga cttttaccat
    12001 ttgactggtt caataccctt gttgccaaga tatgctttag gcaattggtg gagtagatat
    12061 tggccttata cgtcggatga atacttggat ttaatagaca gatttgaaac agagaaaatt
    12121 ccattatcta tcggtgtgtt agatatggat tggcatataa ctgacattcc agctcgtttt
    12181 ggaagtggct ggacaggata tagttggaat agaaacttaa taccaaatcc agaacagtta
    12241 ttgcaacaac ttcatgatag aaagttaaaa ctctccttaa atgtccatcc tgctgatggg
    12301 atacgggctt atgaagaagc ttatcctcaa atcgcaaaac gattggggtt aaatgtagaa
    12361 ctagaagaac ctgctatttt tgattttttt aatccctctt ttagggaagc ctactttaaa
    12421 gatgttcatt atgagctaga aaagcaggga gtagattttt ggtggattga ctggcaacaa
    12481 gggacacaag gtatgctaga tccactttgg cttttaaacc attatcacta tcaggatagt
    12541 tgtaaaaatg cagaaggtgg tttgatttta tcaagatatg caggtcctgg tagtcaccgc
    12601 taccctgttg gtttttcagg ggatactatt attagttgga attccttaag atttcaaccc
    12661 tattttacag cgacagcatc taatatcggt tatagttggt ggagtcatga tatcggtgga
    12721 catatgttgg gggattatga cgaagagcta caaactagat ggctacagtt tggtgttttt
    12781 agtccgatta ctcgattaca tagttctaga agtcctttta atagtaaaga accttggttt
    12841 ttttcagaaa caacatctaa gattatgaag aaataccttc gtttgagaca tcagatgatt
    12901 ccttatctat ataccatgaa tgtaaagaca catgaggaag gtgccccatt aatcagtcca
    12961 atctattatt tctatccaga gaatgatgag agctataatg ttccaaatca atactttttt
    13021 ggaacagaac tgatggtggc tcccattgta gaaaagatgg atttgacatt ccaatctgca
    13081 aaagtagatg tatggttccc tgaaggtgaa tggtatgact ttttttcaga gaaaaaatac
    13141 acaggtggtg tgaagttaag tgtttataga gacatctcga ctacgcctgt gtttgcaaaa
    13201 agtggtgcaa tcattccctt ggttggttct gagataggta tgggtgttga tttacctgaa
    13261 gttgtagatt ggtatgtatt cccaggaaaa caacattctt ttgaaatgct tgaagatcaa
    13321 aatggtcaaa gatataaaac aagattatca atcgattggg aaatgggaat ggtagagtta
    13381 gcattacaag gagattctag tatcgttcca agcaatagaa aacatagaat tcattttaaa
    13441 ggaacgaatg tgtctataat tgaattgcca aataagaatg atacagctaa atttgaatgg
    13501 aaagataata aaaggacatc tttaaatgac gaagttttta gactactaaa gacagcttct
    13561 cttccatatg aattaaaaga tagattgtta aatcaattca tcaatgccaa aaactctcat
    13621 gacttaatga atatcttgca tcatcaggat aaggaattga gagggcgttt gttggaaatg
    13681 atatttacta gccaaaacta attgaaataa ttagaaagtc atttgtttag tgtatatgaa
    13741 gattctgtat ggtattcgtt atcactggtc acattgaaaa tgtgaaatga gcacctacaa
    13801 catagacttt acaacacttc atgtttcata tcatggggtg tttttctatt taagtcaaag
    13861 ccaatcaaaa aatctcacta ttcatcaggt taaaggaaac ctaatcatag tgagattgtg
    13921 aattatagta gagtttgtat cgcctcttca atttgttttg ggtctgtttt tgaagaaaag
    13981 cgttcaaaga cttgcccatc acgaccaatg agaaacttag cgaaattcca ttcgattcgt
    14041 tttcctagtg ggccagattt ctggtctttt aaccagacat agagagggtc tgcttcctta
    14101 ccgttgacct taatcttggc aaaacgtggg aaggtggttt gaaaatgtag gctacagaag
    14161 gcgttgattt cctctgcgct gccgggtgct tgtcccataa actgattgca agggaaatcc
    14221 aatatttcga agccctgatc ttgatagcgt tcatagagtt cttgaagtcc ctggtactgg
    14281 ggcgttaaac cacatccagt agcagtgttg acaatcaaga gaactttgcc acgatagcta
    14341 tccaagggag ttgcttggtt gttttggttc aaaacggaaa aatcataaag tgaagtcatg
    14401 agggcctctt ttctttttct acattgtaac agtttttact tttttcgtcg agtcggatgg
    14461 aagatattgt tgaagaataa gccctcaata tgatagaaac cgtttacaaa taactttaaa
    14521 aatggtatga tttaattaaa ccggtttact tagttgctat aaatctctaa tttgagattt
    14581 agttcctatt gattttacaa tatgtttatt ggagtgtata catgcaaaca aaaacaaaga
    14641 agctcattgt gagtttgtct tcacttgttt tatcaggatt tttattaaac cattatatga
    14701 cagttggagc ggaagaaacg actacgaata ccattcagca aagccagaag gaagttcagt
    14761 atcagcaaag ggatacaaaa aatttagttg aaaatggtga ttttggtcag acggaggacg
    14821 gaagcagtcc gtggacaggg agcaaagctc aggggtggtc agcttgggta gaccagaaga
    14881 atagttctgc agatgcctca actcgagtca ttgaggctaa ggatggggct atcactatct
    14941 caagccctga gaaattaagg gcagcggttc accgtatggt tcctattgaa gctaagaaaa
    15001 agtataaact gcgtttcaag attaaaacag atcataaagt cgggattgcc aaagttcgta
    15061 tcattgagga aagtgataag gacaagcgat tgtggaattc tgcaacgacg tcaggaacaa
    15121 aggactggca gaccattgaa gcagactata gcccgacttt agatgttgat aaaatcaagc
    15181 tggagttatt ctatgaaaca ggaactggga ctgtttcctt taaggatatt gagctggtag
    15241 aggtagcaga ccagccttct gaggactatc aaacagataa acagcttgag gaaaagattg
    15301 atttaccaat tggaaaaaaa catgtttttt ctcttgcgga ctatacttat aaggtagaaa
    15361 atcctgacgt tgcttcagtc aaaaatggaa ttttagaacc tcttaaggaa gggacaacca
    15421 atgtcattgt cagtaaagat ggcaaggaag tgaaaaagat tcctttgaag attctagcct
    15481 ctgttaagga tgcatacaca gaccgtttgg atgactggaa tggcatcatc gctgggaatc
    15541 aatactatga ttctaaaaat gaacagatgg ccaaattaaa ccaggaattg gaaggaaagg
    15601 tagctgatag cctatccagt atttcaagtc aggcggaccg catctatttg tgggaaaaat
    15661 tttcaaatta taaaacgtct gcaaatctga ctgccactta tcggaaattg gaggagatgg
    15721 ccaagcaagt gaccaatcct tcttctcgtt attatcaaga tgaaactgtc gttcgaacag
    15781 tcagggattc catggaatgg atgcataaac atgtctacaa tagtgaaaag agcattattg
    15841 ggaactggtg ggattatgaa atcggtacac ctcgtgccat caacaatacc ttgtctctga
    15901 tgaaagaata cttctctgat gaggaaatta aaaaatatac agatgtgatt gaaaaatttg
    15961 taccagatcc cgaacatttc cgaaagacga ctgataaccc attcaaggct ctaggtggaa
    16021 acttagttga tatgggaagg gtaaaagtaa tagctggttt actgcgtaag gatgatcaag
    16081 aaatttcttc taccattcgc tcgattgagc aagtgttcaa gttggtagac caaggtgaag
    16141 gtttttatca agatggatcc tatatcgacc acaccaatgt tgcctatacg ggtgcttatg
    16201 ggaatgtttt gattgatggc ctgtctcaac tgttgccagt cattcaaaag accaagaatc
    16261 caatcgataa agataaaatg caaaccatgt accactggat tgataaatcg tttgctcctt
    16321 tgctggtgaa tggagagttg atggatatga gtcgtggacg ctcgatcagt cgtgcaaata
    16381 gcgaggggca cgtggccgca gtagaagtac taagagggat tcaccgaata gcggatatgt
    16441 ctgaaggaga aaccaaacaa cgtttgcaga gtcttgtgaa gaccattgtt caatcggata
    16501 gttattatga tgtctttaat aatttgaaga cttataagga tatcagtttg atgcaatcct
    16561 tgttaagtga tgcaggagtc gcaagtgttc caagaacaag ttacctatct gcctttaaca
    16621 agatggataa aacagccatg tacaatgcag agaaagggtt tggatttggc ttgtcactct
    16681 tttccagtcg taccttgaat tacgaacaca tgaacaagga aaataaacgt ggttggtata
    16741 cgagtgatgg gatgttctat ctttacaatg gcgatttgag tcactatagc gatggctact
    16801 ggccaacagt taatccatat aagatgcctg gtacaacaga gacggatgct aagagagcgg
    16861 atagcgatac aggtaaagtt ttaccgtctg ctttcgttgg aacgagcaaa ctagatgatg
    16921 ccaatgcgac agcaaccatg gatttcacca actggaatca aacattgact gctcataaga
    16981 gctggtttat gctaaaggat aagatcgcct ttttaggaag caatatccaa aacacttcaa
    17041 cagatactgc tgcaactaca attgaccaga gaaaactgga atcaggtaat ccatataaag
    17101 tctatgtcaa tgataaagaa gcctccctta cagaacaaga aaaggattat cctgaaaccc
    17161 aaagtgtctt tttagaatcg ttcgattcga aaaagaatat tggttacttt ttctttaaga
    17221 agagttcaat cagtatgagt aaggctttgc aaaagggagc ctggaaggat atcaatgaag
    17281 gacagtcaga caaggaagtt gaaaatgaat ttcttacgat tagtcaggct cataagcaaa
    17341 atggagattc ttatggctat atgctcattc ctaacgtgga tcgtgccacc ttcaatcaaa
    17401 tgataaaaga gttagaaagt agcctcatcg aaaataacga aacccttcag tctgtttatg
    17461 atgctaaaca aggagtttgg ggcattgtga aatatgatga ttctgtctct actatttcca
    17521 accaattcca agttttgaaa cgtggagtct ataccattcg aaaagaaggg gatgaatata
    17581 agattgccta ctataatcct gaaacccagg aatcagctcc agatcaggaa gtctttaaaa
    17641 agctagagca agcagctcag ccacaagtac agaattcaaa agaaaaggaa aaatctgaag
    17701 aggaaaagaa ccattcggat caaaagaatc tccctcagac aggagaaggt cagtcaatct
    17761 tggcaagtct agggttcttg ctacttgggg cattttatct attccgtaga ggaaagaaca
    17821 actaatttgt tcatcatcta gatgaattac atgaaactgt ggaaaataga aaaaatccga
    17881 agaaggccaa atatcttcgg atttttcttt taaaaaagga taagttgata cttatccttt
    17941 tttacttcat tattatgtga ctatagcgtt ttgaaactag aatagaacgt tataactgct
    18001 aaaagatttc tataaattca tttgattttc ctaatcaatt tgttcgtatc ctatttcact
    18061 ccactatata agtccgtctc gctccgtgag gtgcgcgtcg aaggttatac caaaaaaact
    18121 ccaaacgcga tacaataaag gtgttcactc caattgtaaa gcgaaaggag aaaaaatatg
    18181 gcacaaaaga ctcatagttt atcatacaca aagtggatgt gttctatcat attgtgttca
    18241 cccctaagta tagacgaaaa gtcatctata atcaatatag aagtagttta ggcgaaatat
    18301 ttcatcgctt gtagttataa aggtgttgaa atgatcgagg gtcacttaat gccagaccat
    18361 gtacacatgt tagtcagtat tccactaagg ctaagtgttt cgagtttcat gggttattta
    18421 aaaggcaaaa gtgcactcat gatgtttgac aaacacgcca atctcaagta taagtttggg
    18481 aatcggcatt tctgggcgga aggttattat gtaagtacag tagggcttaa taaagccaca
    18541 attaagaaat atagtcaaga ttaaagaaat tatccagtgg atgatttctt cacgagtatg
    18601 aaaatttgag aacgagtaaa gcatgatata tagtaaaatg aaataagaac aggacaaaat
    18661 cgatcaggac agtcaaatcg atttctaaca atgttttaga agcagaggtg tactattcca
    18721 gtttcaatct actatagcac tagataaatt gagtgtaaaa gaatatgagg atccctttag
    18781 ggatagtggt aagtaatacc aaagtctctt aaagaggcaa gtgacgagtc aagagcaata
    18841 aggcttgaac aacgtaaaag ccagcgtctt tagacgctgg ctggtaattt gggcttatag
    18901 ctctgggata aaccacccgt ttgacgggtg gttatgattt tatctgagtg taacatactg
    18961 ttgggcaatc ttgctgatgc ggtcaaagtt gccttgggaa gcgagtttat tgagttcgcc
    19021 accaattcca acggcgtctg caccagcagc gaaccattga gggatgttgt ttagaccgac
    19081 tcctccggtt accattacgg aaacttgtgg gatcggtgcc ttgactgcag agatatatgc
    19141 tggactgaga gtactacctg ggaagagttt gatgatttca ctaccggctt caagtgcagt
    19201 cgtgatctct gtgagggtaa tacagcctgg aatgtacggt gtgctgtaga gattgcacat
    19261 tttcgcagtt tcagcatgga aagatggaga aacaacgtaa tttgctccgg ctagaatggc
    19321 atctctagcg gttacggcat caagcacagt acctgcaccg atacaaacac tctgatcgtc
    19381 ctgatacaag tctacaagtt ccttgatgat ttgtcctgca tactgattgg tataggcgat
    19441 ttcaatagct ttgataccgc ccttgataca agcaatcgag gcttgtagtc cttcttcctt
    19501 tgtatttcct cgaatgacag cgacaatttt ctgttttttt agttcaataa ttgtatctga
    19561 tttggtcatg taattctcct aacgaatgat atcttgtgca tttgccagta aattttcaat
    19621 actagttgcg gaagtggaga gatggtctcc tggaagagtg catttgagag ttgcgctcgc
    19681 aactgcaaag tcaatggtag tttttaggga ggaatgatgg agtagttggt aaagggcacc
    19741 agatataaag gcatccccgc taccaattcg ttgatagact gcagttttta gttggacaga
    19801 ctcttcaaat cgttcttcta gagcataggc ttgatagaca tttttgtctt gctcatcact
    19861 agagcggagg gtatggaaaa tggccttgaa accataggct tcttttaaaa gtcgcatgcg
    19921 attttccacc tcttctaggc tagcactgtc tcttggaaac atctctagat tttggtcatc
    19981 aatcatgaga ggatcaatac cgaagcaata gtcagtaaaa cgtgcaaact tagaaaattc
    20041 atacttggct tctaggactg aaatcatctt tgttctcaga ttgagatcca ttgaaacgac
    20101 aattcctcgg cgcttggctt cttccaagag taggagaagg atcgtacgga cctcttgacc
    20161 gatagctacg gtgattccac taaaatgaaa atggctaatc ccctgaaaga gagaatccat
    20221 atctagcatg tttggccgaa tctggctgat actcgtatgc ttacgatcgt agaaaacttc
    20281 actttgacga caaccaaagc cgttctccaa atagtagagg ccgattcgat cgccaagccg
    20341 acagattgaa ctggtatcga tttggtgctg tttcaagaat gtgagaaaac gatctccaat
    20401 ctcgttggca gggagtgcgg taaagacttt cgttgagata cccagggctt gcaaattaca
    20461 agcgatgtta atttctgatc cgccaaaata agtcgaactg gcaacatgat cgccgatact
    20521 ggtggcatct aatggtgaga ttcgaattaa tggttcgcca aacagtaata ttttcgtcat
    20581 ccattagttc ctttctggtt tagaatagct ttacttggct aatacttctt tcaaataagc
    20641 agcgatttca tcatcttggc agttttcaaa gaagtattct tggaagtatt tgccagagat
    20701 ggtgtctttg aggaagtctt ggtcgattgt tttaaggatg gtcatcaaat cattgtgggt
    20761 gatttgtttc acctcgttta agatacgagc gttgcgttgt tcagggatta cacgttctct
    20821 tgggtagcca ccgcccattt cttcagcaaa taagcgttca aacatcaatt tgagggtcag
    20881 ttctgccccc cagccaaatc ctttggcata agggatagac aaggcgttac caccattgat
    20941 ttgagaataa aggtaagcgt cagttgggtc cactgctaga ccacagacaa caccagggaa
    21001 gctgtttaaa gcaagcatag cccctacacc cgtaccacag ccggtaacaa caaagtcaac
    21061 tgcctttgta tttaaaagga tggcagccat tagtccgttc tgcacataag ttaattgact
    21121 ttctccttct tctccacgca taccatagtt aaataattgg tagtcttttt tatctgtcgc
    21181 ttcttttaga ctatcgtaaa taatgtgatt cttgctagct tgactatttt cattgattaa
    21241 tgcgattttc ataagatctt ctttctattt ttactcaggt tgttttccga tgtaggctaa
    21301 gataccgcca tctacatata ggatgtggcc attgacaaaa ttgctggcat cactagcgag
    21361 aaagacagca gggcccatca aatcttcagg atttccccaa cgtgcagcag gtgtttttgc
    21421 aatgatgaac tggtcaaatg ggtggcgaga accatcttct tgcaactcac gaagaggtgc
    21481 tgtttgagga gtggcaatat aacctggtcc aattccgtta cattggatat tggctccacc
    21541 gtattcagac gcaatgttgc gggtcaacat tttcaagccc cctttagcag cagcataagc
    21601 gctaactgtt tcacgtccca gttcgctcat catcgaacaa atattgataa tctttccatg
    21661 ccctttcttt atcatagaag gaataactgc ctttgaaacg ataaatggtg cgtttaagtc
    21721 aatatcgatg accttacgga aatcagcggc gctcatttcg cacattggaa ttcggcggat
    21781 aataccagcg ttattaacga ggatgtcaat gacaccaacc tcttgttcga tttgcttgac
    21841 catggcttgg ataccgtcct cgtctgtcac gtcacagaca tatccatggg cttcgatgcc
    21901 aacttcacga taagcttcaa tccctttatt gaccagatct tgattgatat cgttaaagac
    21961 aatagtagcg ccggcttcag cgtaggattt ggcaatagca aatccaattc cataagaagc
    22021 gccggtgatg agagcaattt ttccttttaa agaaaactgc tcaattgaga atgatgtatt
    22081 tgtcatttga tacttccttt caaatttgtt aagacttctc tataa
//
LOCUS       DAVMCN010000028        22099 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVMCN010000028 DAVMCN010000000
VERSION     DAVMCN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.028"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..539
                     /locus_tag="VYP85_001260"
     CDS             <1..539
                     /locus_tag="VYP85_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV1881780.1"
                     /translation="HYFLQRDTAKESILDYSFAHGYCGIAYALFAYSKVLEPSMFYND
                     LHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLCMYDCDGNKDIISKYQEF
                     VFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILACSERDDHGLLMFQGDSG
                     KADLFDFGIGSMGYIGVY"
     gene            582..1814
                     /locus_tag="VYP85_001261"
     CDS             582..1814
                     /locus_tag="VYP85_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1881781.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDNLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVTFNTHN"
     gene            complement(1932..2951)
                     /gene="cbpC"
                     /locus_tag="VYP85_001262"
     CDS             complement(1932..2951)
                     /gene="cbpC"
                     /locus_tag="VYP85_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1881782.1"
                     /translation="MKILKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDGGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMVTGWVKDDSTWYYLNAGNGDMKTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(3049..3738)
                     /locus_tag="VYP85_001263"
     CDS             complement(3049..3738)
                     /locus_tag="VYP85_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881783.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(3750..5174)
                     /gene="gndA"
                     /locus_tag="VYP85_001264"
     CDS             complement(3750..5174)
                     /gene="gndA"
                     /locus_tag="VYP85_001264"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1881784.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(5250..6644)
                     /gene="mapZ"
                     /locus_tag="VYP85_001265"
     CDS             complement(5250..6644)
                     /gene="mapZ"
                     /locus_tag="VYP85_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1881785.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(6657..7814)
                     /locus_tag="VYP85_001266"
     CDS             complement(6657..7814)
                     /locus_tag="VYP85_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1881786.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(7899..8279)
                     /gene="rnpB"
                     /locus_tag="VYP85_001267"
     ncRNA           complement(7899..8279)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYP85_001267"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(8300..8629)
                     /gene="gpsB"
                     /locus_tag="VYP85_001268"
     CDS             complement(8300..8629)
                     /gene="gpsB"
                     /locus_tag="VYP85_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1881787.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(8699..9226)
                     /locus_tag="VYP85_001269"
     CDS             complement(8699..9226)
                     /locus_tag="VYP85_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1881788.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVVQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            9292..9888
                     /gene="recU"
                     /locus_tag="VYP85_001270"
     CDS             9292..9888
                     /gene="recU"
                     /locus_tag="VYP85_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1881789.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            9885..12044
                     /locus_tag="VYP85_001271"
     CDS             9885..12044
                     /locus_tag="VYP85_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1881790.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(12211..17514)
                     /locus_tag="VYP85_001272"
     CDS             complement(12211..17514)
                     /locus_tag="VYP85_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1881791.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGSVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTNKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGEGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWIDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKRTALVADD
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKVQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPIVEKPEFKLNSLASEQGKTPDYKQEIA
                     RPETPAQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(17815..19797)
                     /locus_tag="VYP85_001273"
     CDS             complement(17815..19797)
                     /locus_tag="VYP85_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1881792.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKSKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(19975..20498)
                     /locus_tag="VYP85_001274"
                     /pseudo
     CDS             complement(19975..20498)
                     /locus_tag="VYP85_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170108.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
     gene            complement(20485..21594)
                     /gene="glf"
                     /locus_tag="VYP85_001275"
     CDS             complement(20485..21594)
                     /gene="glf"
                     /locus_tag="VYP85_001275"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEV1881793.1"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYVNSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKITEQTADMKDVEPKNLEEQAIKLIGPDVYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASAEKVVFTGMIDQYFGYKHGELEYRSLRFDHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDEKNNAMFAKYQEEASKNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFGYDKK"
     gene            complement(21608..>22099)
                     /locus_tag="VYP85_001276"
     CDS             complement(21608..>22099)
                     /locus_tag="VYP85_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEV1881794.1"
                     /translation="QTYVIQTFRLWTWFFYYLLGGYIAQFTIEEIESRFKNWMKIVSI
                     LLLLISPIILFFIAKTIYHNLFAEYFYDTLFVKVSTLGIFLTILMLTLNENRRESIVS
                     LSNQTMGVFIIHTYIMKVWEKVLGFNFVGAYLLFALFTLSVSFIIVGMLMKIPYFNRI
                     VKL"
BASE COUNT         6327 a         4951 c         3943 g         6878 t
ORIGIN      
        1 atcattattt cctacaaaga gatacagcca aagaaagcat tttagactat agctttgctc
       61 atggatattg tggaattgca tatgctttat ttgcctattc taaagtctta gaaccttcta
      121 tgttctataa tgatctccat acattccata ctgaattaaa aaaattatta gaaaaagtta
      181 cttctaatac tgaaaattta ggaaatttac aactttcttg gtgcaaagga atttccggaa
      241 taatcttata tctttgtatg tacgattgtg acggaaacaa agatattatt agtaaatatc
      301 aagaatttgt ttttaaccat catctaaaaa tgatgacagg atattgccac ggaataacta
      361 gcttactaca aaccactgtc tacaatcaaa acaaattact gatgaaaaaa atccaacagg
      421 taattttagc atgttctgaa cgagatgatc acggtttact gatgtttcaa ggagatagtg
      481 gtaaagcaga tttgtttgac ttcggaatag gaagcatggg gtatattggt gtctattaaa
      541 taataaattc ccattcgatg tgcagacata aggagaaaag tatgaaatta ttttggacaa
      601 acaacatata tagacagttg ctgctaaaca gctgtttttc atcattcggc gacagtattt
      661 tctacctcgc cattatcaat tatgtggctc agtacaattt cgctccgcta gcgattttac
      721 tgatttccat ttcagagatg gttcccctac tatcgcaact ctttctcggg attctaggag
      781 attttcaaga aaatagagtc aaacacgcac tctggattgc caaaatcaaa atcctgctct
      841 acgctatttt gacagtattt ctcgtcttgt cgcccttttc attagtttca gtcattatga
      901 ttgtcatcat caacctcatc tctgacacct tgagctacct gtctgcctac atgatgaacg
      961 ccctctacat cagtgtaatt aaggacaacc tgcatgatgc catggggttc aggcagtctc
     1021 tgatgagggt tgtccgtatt gtcgccaatc tggctggcgc attccttatc aatgttataa
     1081 gtattcaaac tatttccctt atcaacactc tgacttttgt cattgccttt ttgggcctgt
     1141 atgttattcg acataccttg tatgaggttg aaaaaaggat tgaaatgtca catacagcac
     1201 tgagttttaa gaaatatttt caacatctta aacagtcgct ggctgtgctc ctgaggttaa
     1261 aagataccgt catactactg tttctgacga ccagtatgat tgccatcttg gatgtgtccc
     1321 ctcggctgat tgccctccgc ttcatccaac agacactagc acaactgagc attgggcaac
     1381 tcctcgccat gctctccatc atcatttctt gtggagctat ccttggcaat atgaccagca
     1441 gtaatctatt taaaaatatc cgtttcacgc acctcttggt tttctgtgag atttccctat
     1501 tggctctaat aactagtatc ctttgtcaag cctatatcgt aattttcatg accagtttca
     1561 tcagttctac gattatcggc attctcagcc ctcgcctaca agcagctgtc tttgcccata
     1621 tccccagtga caagatgggg acggtgggct ctgctctgag cacagtagac attctcgccc
     1681 cgtccctgct ctccctatta gccctatcca tagcatcggg cgtttcggtg cagttagcat
     1741 tgatattttt gtatcttatt ttaattgctc ttatcttttg tcaatggtta gtcacgttca
     1801 acactcataa ctaacgaaaa agcatgtgta gatttcacat gcttttaatc tccccaatcg
     1861 tcaggtcaag tacaacaaag tcacttcttt gattaagcga gtgttctaat ataattataa
     1921 gcgccctgtc attaccgaac ccattcgcca ttatagttga cagaatagcc atctacggtc
     1981 gtattcactg ccaaggcacc tgagctataa gcgtagtacc atctgccatt gacctggaac
     2041 caacctgtct tcatgtctcc attacctgca tttaggtaat accaagttga gtcatctttc
     2101 acccagccag tcaccatggc gcctgacgaa cggagatagt accatttgtt cccaaggttt
     2161 tgccatcctg ttttcatatc gccatttggc tggtctaaat aataccaagt ggtaccttcc
     2221 tgataccagc cagtggccat tgctcctgag gaacggaggt agtaccactt attacctaga
     2281 tattgccaac ctgtttgcat aataccagtt gttggatcta ggtagtacca tggagcaggt
     2341 ttgcttctat caatgtcaat agtaacatga aaatcttgag tccaaccctt agcaacttca
     2401 ccaattggta gtggattgta agaatcatca ccaaaatttc ctagcttatt taaataatac
     2461 caattgccgt cttcataaat ccagcctgtc tttacagcat aattattatc aaaataataa
     2521 gttctctttt cagcagatag aggatattgt tcaccgtata cttttcctgt attttcagac
     2581 gtttttgcct ctagtacttg tttatctgtt tgttctaaca aagcaccatc ttgtccaaaa
     2641 tagtaccact tctcctgaag gccaatttca ttaactggtt ggttatcgaa taaattatca
     2701 cgataacctg ttccaggaat ttctaagtat tgccaaccga caaccatctc tcctccatca
     2761 ccaaaatagt aggttttacc gtctatttta tgccaataga ttgctttatg atcatctttt
     2821 acataatatt ttctattatc cttatcaaca aatcggccac ctgtggtatt cgcaaatacc
     2881 gtatttgtag ctagcaaacc aaagaaaaag actgctagta gaacttgcat catttttttc
     2941 aaaattttca tctatatacc ctcctaaaac gattgtagca aagacccgac tgcatgtcaa
     3001 tatataaaaa ctcctcaaaa aagcagttac acaactgcaa ctgcttttct attcttgcat
     3061 ggtgtaacca acaccacgca cggttttaat gtagcttttt tggcctttaa catcaagctt
     3121 gctccgtaga tagcggatat agacatctac gatatttgtc tcggtcgcac tttcatactt
     3181 ccaaacactt tccaacaatt gctcacgagt caatactttc ttgcttccca taagtgtcgc
     3241 caaaaggtca tactcacggc gggtcagagc aatcatctct tcaccacgat aaaccgtgtg
     3301 atgttcaaca tctatcctaa gattgcggta ggtccttgga actttcatca gactgcagtg
     3361 ttgatcaatg aagtcccgac ctcggaagat cgccgaaata cgcgctacca gattttcgat
     3421 aaggactggc ttatagatgt atgaaactgc aaaacgctga acaacttcca gctcttcttg
     3481 caagtcttcc caatgatcta aaatcatgat gactgaggca ggtttagttc gactcaattt
     3541 ttctgcaaaa tcctgagcca tcatatctcc cagattaacg ttcaataaaa tcaaatcata
     3601 gtctgtctga agagccatgg agagggcttt ttgcccctcc tctaccagat caacccgata
     3661 ctgctctttc tggagttcca aacttaaaaa atgagctaga tttcgttctt tctcaagtaa
     3721 taaaatccgt ttccccatgg ctgacctact tatttttcgt cataccaaga gtagtggaag
     3781 gttccttctt tgtctttacg ttggtaagtg tgagcaccaa agtagtcacg ttgtgcttgg
     3841 atcaagttag ctggaaggtc agctgaacgg tagctatcaa agtaagtaat agctgctgag
     3901 aaagttggca ctggcacacc agcttgaacc gcaagagcta cgatatcacg cactgcttgt
     3961 tgatacttag cagtaacatc caagaagtat tcatccaaaa gaaggttggc aaggtctgca
     4021 tcacggttgt aagcatctgt aatcttttgc aagaaacgag aacggatgat acagccatca
     4081 cgccagatag atgcgatatc tgcaaatggc aagttccagt tgttttcttt agaggctaca
     4141 cgcaattgag caaatccttg tgcgtatgaa atgatttttg agaagtaaag ggcttgacgg
     4201 attttttcaa tcaattcagc cttgtctcct tcaaagttga aggcagctgg ttttggaagc
     4261 accttgctag catgtacacg ttcttccttg taagttgaaa tgtagcgtgc aaacactgac
     4321 tcagtaatca gtgacaatgg tacaccaagg tcaagagatg attggctagt ccatttacca
     4381 gttcccttgt tacctgcagc atcaaggatg tagtctacga ttggtccatc ttggccttca
     4441 tcgtctttac ggctcaagat atcagctgtg atttcgatca aataactgtc taattcaccc
     4501 ttgttccact cagtaaagat ttcagccata tcctctgcag aaaggcctag caagtgttgc
     4561 atcaagtcat agctttctgc gatcaattgc atatcaccgt actcaatacc attgtgaacc
     4621 attttcacat agtgaccagc tccatcaggg ccgatgtaag tcacacatgg tttgccatct
     4681 tctggtgctt tagctgagat ttcttcaaga acatccgaaa ccaattcgta ggcctctttt
     4741 tgtccaccag gcatgataga aggaccttca agggcacctt tttcaccacc agaaactcca
     4801 gtaccgataa agttgatacc tgagtttgcc aattcttcat tacgacggat ggtatctttg
     4861 tagaaagtgt ttcctccgtc aatcaagata tcacccttgt caaggtgcgg aagaagggct
     4921 tggatagtag catctgtacc aggtccagct tgaaccatca gcatgatacg acgaggtttt
     4981 tcgattgagt ttacaaaact ttcaacgtca tagcttggta caaagttctt ttcaggatgg
     5041 caagcaatca catcttccgt tttttcttta ctacggttgt agatagcaac tgtgtaacca
     5101 cgagattcaa tattaagggc aaggttacga cccattacgg ccatacctac aacaccaaag
     5161 ttagcttttg tcatttgaca ctcctcttgt ttcatttgtt ttattttatc atttttactt
     5221 ttgaaaagaa agaattttgt aacgactgct tagtagtcca agtcatccgc atgaccagcg
     5281 ccatttccga caaaatatcc tgtcttacag ttaagggtaa agagataggt tccatctggc
     5341 ttatagaggt tgtaataacc attgccgtta acgatattga cacgttcaag gatatattgg
     5401 tctccagtga tatagccacg tgaacgtgaa gttgctagaa tttgttccaa aacaccatcc
     5461 gcaaaatccc aggcagagtt attactatca tcaatagcag actgattata ggcaacacga
     5521 ctggcacttc tttgaacagc aacccctgca ctcgagagac ccatattgac ttcactgcga
     5581 ctacttctag tctcatttga actacttggt tttggctcac tagtcgtatt tgaacttgct
     5641 tgacttgaac ttgagctgct agtttgactt gaacttgagc tagaagtact tgtttgctgg
     5701 ctcttaccaa gactgatagc cttatctagc actttatcaa gctccgtatt tccagtttta
     5761 atatccgtaa atttagcatc cgatttggct ttggcattgg tatccaacac accatccaca
     5821 atagctggtt tctcaaattg agcattgaca tcttgaatag ccttgatttg cgttgctaga
     5881 ctatcatatt tagatttggc aagcgtatgt tcacgactac cttccagctt atcaagtaaa
     5941 gtcttgagtt gattcagttt atcaaactgg ctatttttca aagccgtttt attgctatct
     6001 gtgtaaaagg cgtcataaag tgtattaaaa tcatccacat ccgattgatt ggctgtagtt
     6061 gattgagaag tttcaatttc cttggtcgaa cgagccactt gacggtagac ataataagca
     6121 ctgacacaaa taattactga tacaagcgcc aaaacggtca aaataaagcc ttttttactt
     6181 ttcttttctg agtcctcttg atccagacga gaaaggtttt gctcctcttc cacttcttca
     6241 gtcatttctg ttggattttc atcatctagc aatagaggat ccaagccttg ctcctcatcg
     6301 tccagaggca agggtagtaa gatgtcttca gaagatggaa cttcctccga agaagcttct
     6361 gacttctcta cagcctcacg catctcttga attaaatcat ccagactctg agtttcaacg
     6421 aactcctctt ttttgtattg acgagtcgca aacttatccg cctcaatttc atctctgtgt
     6481 tgcttaacat acttgtccaa aatggaatcc tcaggcaaga ctcctgcttc cacttcttca
     6541 tttttacgaa tagcttgacc aactgttagc tcttttgctt catcaaaatc aaattgcggt
     6601 tcttgacctt cttttttatg acgatttcgt ctttttttac tcatgagtat ccctttctat
     6661 tttacctctt gccgtttgac acgctgacca aaatattgat atagatccac tttcaaggtt
     6721 ccgttgtata acttacgctt cttatctgct tggctaccat acttgctttc aaaagcttca
     6781 tcactagtca ggataaattt gctccaagtt ttcagcggtg caaatacttg ccccatctca
     6841 gcatagagct tggtcacccc tgcatcatct gacaaacgtt caccataagg cggattggaa
     6901 atgattactc cattgatttt atcggaacgt aaatcctgca cgcgcatctg cttaaaagta
     6961 atgtctcctg caacaccagc tgcctgagca ttggccttag caatttccac catgcgagca
     7021 tcaatatcac agcccatgat atccagctca agctcacggt ctactttttt agccgcttct
     7081 gtgcgcactt cttgaatcaa gcgatcgctg atccagttcc attcctcaaa tgcaaaagag
     7141 cgacgaagac ctggcgccat ctttctagca atcataactg cctcaataca gaaagtcccc
     7201 gaaccacagg tcggatcaat caaaggcttg tctggatacc agttagaaag ttgtaaaatg
     7261 gctgctgcca tattttcctt gataggagcg ccaccttttt cggtacgata accacgttta
     7321 aagaggctag acccggtcgt atcaatcatg acagttgcca catctttgag aatagagacc
     7381 tcaatcttaa actctgggcc attctccatc agaggaaccc cttctgggcg agcatagtgt
     7441 ttctgcaatt tcttgacaac agctttctta gaaatagcct gaacactggg ctcattgtga
     7501 agtttggact taacacattt agcttttgaa atcgggaacc gagctccaag tggtaaataa
     7561 ttttcccaat ctaaagcgaa aactccctga aatagctctt caaaagtctt agctgggaac
     7621 gttcctacga taattttgat acgatctgct gcccgaagcc aaaggttggt ttcgataata
     7681 gctctcacgt ctccttgaaa acgaacacgt ccattttcaa cctgacaatc gtagcccaac
     7741 tctcgcactt cacgaccaac gacagcctca agccctgctg ccacagttgc aattaaatta
     7801 aattcttttt tcatgttaca gtcttgcaag acctttctat atgtccactt taaaaaatga
     7861 ggttgagaaa atttctcagc cccaacctat atgcaatttt ctataagcca tgttttgttc
     7921 cagaagtgac taggaccact tccttcgata atcatctgtc taccactaac agctctagct
     7981 gatagcagtc agaatactac gttcgtttcc gcgtactcca tgccccgacc aaaatttggg
     8041 ttgctagctt gaggggttta ccgcgttcca ctctctctgt ttccagaaag actccgtcac
     8101 tgtggcactt tcaagcctac tctggcctat ccaaggactt agccatttca actgccgtaa
     8161 cgattcctcg tccctaggct tatggtttcg cctagcacaa acactacagg catcacagcc
     8221 tgtgctagca tggactttcc tcatgagaag caattctcct cacgcgatta tccaaaaatt
     8281 gcacatctca aataactact taaaaatctg agttatctaa aatttgttta ccaaaaactt
     8341 ctttttccaa tctattcagg cgtttcaaaa tatcaaaatt cgtcatagaa cttgtaattg
     8401 ccgcttcaag gggttctgct tgaactggtg aaggtttcgg tttacgagtt aattcttcct
     8461 tcaaatccgc aatttcctga cgaagtgact tgaccaaggc agcataggtt tcatagtcct
     8521 tgatgacatc gtccaaaaac tcgtcaactt ctactttatt atagccacgg acttcacgtc
     8581 caaactcttg ttcaaaaata tctttcgctg aaaaaataat acttgccatg tctctctcca
     8641 ttctcgcttg ctagtattat tatataaaaa aaggcaaaca aaaatcaagg tcaaagcttc
     8701 aattttcgga aaaattttca gcaagttcat ttaattgatc aaatgttaat ctctttataa
     8761 aatagtcctc ttgatttttc atcttttggt aaaaataagc tagtttcgtt tcattttctt
     8821 catcataaaa aagataggaa ctagtcgtgt tttccagcaa aaactgctgg taatctctta
     8881 actgcccctt gtgttcatag cgaggataag catatttgac aaagtctacc tgcttaaagc
     8941 gactcagttt catctgattg ccttcattcc aattttcccc atgggtttca aaagcaaaaa
     9001 tggtggccaa ctggaaaccg tattcggttt tcatctcctg aacaacctct aaaacccaat
     9061 attcaaaccc caaacttcct gtaaacacaa gccaagacac cccatctgct gccatagcct
     9121 ctaaatcttt acgtatcgct tttttaatca atttaagacg aggatcctta tcagaaaata
     9181 aacccaaatc aaaagcagaa tagcctaaaa ccaaagctgt agccattttt aaccctttct
     9241 gtgcaaatta tggtataata aagtgatgtt attgtaccaa taaggagaat tatggtcaac
     9301 tatccacata aagtttcatc acaaaaaaga caaacatctc tttctcaacc caaaaatttc
     9361 gcaaatcgag gaatgtcttt tgaaaagatg atcaatgcta ccaacgacta ctatttgtct
     9421 cagggcttgg ctgttataca taagaaacca actcctattc aaatcgtaca agtggactat
     9481 ccacaacgaa gtcgtgccaa gattgttgaa gcctattttc gacaagcttc aacgacggac
     9541 tattctggcg tttataatgg atattacatc gactttgaag tcaaggaaac aaaacaaaaa
     9601 cgtgcgattc cgatgaaaaa ttttcatcca catcagattc agcatatgga acaagtcctt
     9661 gcccaacaag gaatctgctt tgtccttctt cacttttctt ctcagcaaga aacctactta
     9721 ttgccggcat tcgatttgat tcgcttctat catcaagata agggacaaaa atcaatgcca
     9781 cttgaatata ttcgagaata tggatatgaa atcaaggctg gtgccttccc tcaaattcct
     9841 tatctcaatg ttatcaaaga acatttatta ggtggtaaaa caagatgaac aaaccaacga
     9901 ttctgcgcct aatcaagtat ctgagcatta gcttcttaag cttggttatc gcagccattg
     9961 tcttaggcgg aggagttttt ttctactacg ttagcaaggc tcctagccta tccgagagta
    10021 aactagttgc aacaacttct agtaaaatct acgacaataa aaatcaactc attgctgact
    10081 tgggttctga acgccgcgtc aatgcccaag ctaatgatat tcccacagat ttggttaagg
    10141 caatcgtttc tatcgaagac catcgcttct tcgaccacag ggggattgat accatccgta
    10201 tcctgggagc tttcttgcgc aatctgcaaa gcaattccct ccaaggtgga tcaactctca
    10261 cccaacagtt gattaagttg acttactttt caacttcgac ttccgaccag actatttctc
    10321 gtaaggctca ggaagcttgg ttagcgattc agttagaaca aaaagcaacc aagcaagaaa
    10381 tcttgaccta ctatataaat aaggtctaca tgtctaatgg aaactatgga atgcagacag
    10441 cagctcaaaa ctactatggt aaagacctca ataatttaag tttacctcag ttagccttgc
    10501 tggctggaat gcctcaagca ccaaaccaat atgaccccta ttcacatcca gaagcagccc
    10561 aagaccgccg aaacttggtc ttatctgaaa tgaaaaatca aggctacatc tctgctgaac
    10621 agtatgagaa agcagtcaat acaccaatta ctgatggact acaaagtctc aaatcagcaa
    10681 gtaattaccc tgcttacatg gataattacc tcaaggaagt catcaatcaa gttgaagaag
    10741 aaacaggcta taacctgctc acaactggga tggatgtcta cacaaatgta gaccaagaag
    10801 ctcaaaaaca tctgtgggat atttacaata cagacgaata cgttgcctat ccagacgatg
    10861 aattgcaagt cgcttctacc attgttgatg tttctaacgg taaagtcatt gcccagctag
    10921 gagcacgcca tcagtcaagt aatgtttcct tcggaattaa ccaagcagta gaaacaaacc
    10981 gcgactgggg atcaactatg aaaccgatca cagactatgc tcctgccttg gagtacggtg
    11041 tctacgattc aactgctact atcgttcacg atgagcccta taactaccct gggacaaata
    11101 ctcctgttta taactgggat aggggctact ttggcaacat caccttgcaa tacgccctgc
    11161 aacaatcgcg aaacgtccca gccgtggaaa ctctaaacaa ggtcggactc aaccgcgcca
    11221 agactttcct aaatggtcta ggaatcgact acccaagtat tcactactca aatgccattt
    11281 caagtaacac aaccgaatca gacaaaaaat atggagcaag tagtgaaaag atggctgctg
    11341 cttacgctgc ctttgcaaat ggtggaactt actataaacc aatgtatatc cataaagtcg
    11401 tctttagtga tgggagtgaa aaagagttct ctaatgtcgg aactcgtgcc atgaaggaaa
    11461 cgacagccta tatgatgacc gacatgatga aaacagtctt gagttatgga actggacgaa
    11521 atgcctatct tgcttggctc cctcaggctg gtaaaacagg aacctctaac tatacagacg
    11581 aggaaattga aaaccacatc aagacctctc aatttgtagc acctgacgaa ctatttgctg
    11641 gctatacgcg taaatattca atggctgtat ggacaggcta ttctaaccgt ctgacaccac
    11701 ttgtaggcaa tggccttacg gtcgctgcca aagtttaccg ctctatgatg acctacctgt
    11761 ctgaaggaag caatccagag gattggaata taccagaggg gctctacaga aatggagaat
    11821 tcgtatttaa aaatggtgct cgttctacgt ggaactcacc tgctccacaa caacccccat
    11881 caactgaaag ttcaagctca tcatcagata gttcaacttc acagtctagc tcaaccactc
    11941 caagcacaaa taatagtacg actaccaatc ctaacaataa tacgcaacaa tcaaatacaa
    12001 cccctgatca acaaaatcag aatcctcaac cagcacaacc ataacattta tcacccagat
    12061 ttttctgggt gattttgtca tagcactatt gtatttatgt gcttaacaaa agcctgagaa
    12121 gacatcttct caggcttttt ctgtactata aacctcattg gaaaagatag agactgcttc
    12181 cgtaatcttg ttaagaggtt ttactaaata ctagtctttc ttcgttttta ctacaaagag
    12241 agcagatagg gctaggctaa cacctgctag gaagagggct gtgtcagatt gactctcacc
    12301 tgttgctggc aagatttgtg caggtgtttc tggtctagct atttcttgct tataatctgg
    12361 cgtcttacct tgctcggaag ctaaagagtt aagtttaaac tcaggtttct ctacaattgg
    12421 agcatctggt ttcgtagcag aatcttttaa ttggttgaga taatctgcaa agtattccac
    12481 cattctttcc gtcaagagat ggttatccgt cgcatatttc atgcttgcct gaacgctagc
    12541 tacttcctct tgattgtctt tgtctgttaa tttctgaacc ttagccaaag ctgcttcata
    12601 gcctgacaag tcaagaggtg tttctgctac ctgtggacga gtaaagataa gttccgctgc
    12661 agattggtat ttatcgccac catctccgta agtcttagta cctgtaagga caattttctt
    12721 agccttaatt gtcttaccaa aatcaatgtc ttttggctta ttgttatctg gccaatcagt
    12781 tgcagtaaag gtatgctcct tgccagactc atctgtcaca acaagtttca catcacgcaa
    12841 gttaccattt gaacctgatc cacgtggaac ataacgaagt ccagtgattt cagttggttc
    12901 tttcaagacc atggttgcag gcttgcctac atctccacca ttccaagatg tatgccatag
    12961 actagacaca ttgccatcaa aggcattctc aagaccttca cctggttgag ctggcgcatc
    13021 caaactttca aagtcatctg ctaccaaagc cgttctcttc tgaaccaaag cattcttcaa
    13081 ggcttcaatc ttggcaatct ctgcacgcgc ttcttccaca ctgatatcat catcggcctg
    13141 actgaggtta aagaccgcct ctttcaaagc atccatagac tctttggtgt agttagtcat
    13201 ggcaaccgtt ggcaagtagt tcttcagagc attttctgtc aacatcttac ctgttagggt
    13261 aatttcttcg atttgaagat tatccatcat gaagtcgtta taaccacgga agttggcatt
    13321 tccaccagaa tcaccacgag tattacttgc atttccagtt gagtagatac ctacccaagt
    13381 atctcctgtt tctgcacctg tcacaaggaa ggttgccttc ttggctttct tagaatctat
    13441 ccaagtattt ggcaattcat gcatttccaa gttgcttgct tgagtgccac gacgacctga
    13501 ctggaattct cccttaccga ctacaaaagc ataggtattg tctgaacctg cttcgtattc
    13561 aaaggttaca cggtaggtct tacctgcttc aaaacggaag ttttgcggaa tagtttggta
    13621 aaccaagtta cgacggctca ctagtccatt tgtcttgagt gaccaatttc cttcgataac
    13681 atcatcgact ttcttaccat tccaaccacg ttgtgtatat ggatcgtgtt tttcagacaa
    13741 gtgagtgcgg ttatcttcaa caccttcgac accacccact acaaatggga agataccctg
    13801 agcaacattt tcaaagtctt gcttgaaggt gccttcacct gtatcatgct tgtctccgta
    13861 catgcttgaa ttgttttcaa aggtacgaat ttcatcaaag taagttgctt gatcaccagc
    13921 ttcacgactc aaagtcagag taacatttga gacgtccgat cctgttgtaa agaaggcgta
    13981 catgttttgg aagtaacttg tatcgtcaac tgtagcattg tcacgacgtg tattgtgggc
    14041 gtaggcctta acatagttga gcgcgagaga cttattggta taagtagtca cttctttttc
    14101 accagtattc acagtgatac ttgccttggc attactacgg ttatctacac caacataaac
    14161 ggcatacttg gtatttggtt tcaagccagt taatttctga gtgagactaa ctttttcttt
    14221 gtttccttga atacgaagca tatcgtttgc cccttgagac ttgacaattt ctgccttaga
    14281 agcatcgcct gaaatggtcc aatgtttcaa ggtaccgcta ttaaatcctt ggtcatagat
    14341 gtgcatgcct tcactccatg acatttcagg attagtttgt ttcgaacgat agagaacgta
    14401 tggttgattt gctagaagat ctagggtaat tttaccatct tttacagtta gttcttgctc
    14461 ttctgtctta ccttggtcag ttagcttgta aaggtaaacc ttgctctttg cccaatcgct
    14521 tggaagggtc caagttgttg caccggcctg cgtattgaag tagtacatct tttccttatt
    14581 agtagaaagt ttcttaccat ttgcatccca gttccaagga gtcaagtaag ctgaaccatc
    14641 ttggatgaca cgtccgttga gagttactgt acgttcgcga tattgtgggc tattgacatc
    14701 atttgactta cgagttacaa ctactttatt attgtcagca tctaccaatt ccactcgcat
    14761 ttctggagtc catttatagg tgctaccgtt atcggtcata gtcaccggtg taccattttc
    14821 ccatttactt acagtgaagt gttggaagta cttagtcatg acgtcatggg caaataagtt
    14881 ggttacatag ccattgtagt cacttcttcc ttgccagcct tcaaagtctt tcatgctgta
    14941 gccacctagc agtggatagt tggctgcacc accataactt ctgtagtccc caacccaagc
    15001 atctttttgg tggttacgga taaagcgggt gatggcactg ttgatacctt tattggtgta
    15061 gccaccgtag gtcaagtcag ctgcccagtg atggaaggta gagtcgtact caccaccatg
    15121 gccccactcg atcgcaaagc gccagccttg tttgttaatt tctttagcaa gaacgtgggt
    15181 agcccaggca ccgttatcac ctgattgacc attaccccaa acgtccacat agataaagtc
    15241 gagaccgtca ccaagttttt tcttcaaatc ttcccaacgt gccaaacgac catgagctag
    15301 gtcataggca gcatcaatgt tgataccttg atctagccag ttccaaccat agctatagct
    15361 tccatctgga ttcttacgga gaattttttc attgaagtat ttagactcag gataagtttc
    15421 tgaagcgtta acgtggatac ctagatgagc tccatatttc ttagccttct caattagggt
    15481 cttgaagtct tcgacaccac cgatacgctt accaatatca gcatagttca agtgaccaga
    15541 gtcatgacct tcactaccat atcctttaag gagaacacct tgcccaagac catctgtgtg
    15601 gagattgatt ttcttgatac catccaaggt cataaggaat gggttttgtg cttgagaacc
    15661 aaagttcatc gcgatacggt aagctgtgat atccttaact ttttcccaac cttgagggtt
    15721 gttcataatg ctacgataag caatggcacc atcttgccaa tcaactttct tgtctgcatt
    15781 ggcatcttca gtgataacaa ccttagcact tggaagttcc ttcgtgtatt ctgggaaaac
    15841 aatgccctta taagcttttt cccattgcca ttcagagctg tggattccta catagttggc
    15901 atttccgact gtttctttat aagctgtcaa acgagtccag tcattcgaac caccaccata
    15961 gctgttttga gagttactcc aaacaccagc agcaagctta tctgtagaaa caaatccata
    16021 catgtaaccc ttagccaaat ccttcattgg attggttaca tcgatatgat catctccgct
    16081 gacatgcgta ttgtttgaca tggttgcccc atcaaactta gcaccagttt gatcactaga
    16141 aacagagact aaagcattgc cgaggaaact aatagaagaa agtagttttc tttcgtcatc
    16201 aatcttttga cctggagtga cttgattgtg gttgacaatc ttggtcacat caaagtgcaa
    16261 ttgattgtcc acaacttgca agcgtactgt catttccgca ttgattaagt gagcatcatc
    16321 gcgaatcttc atcaagtact ctgctgttgt ctcattgatt ttcttataag tgacttcagg
    16381 ggtgattcgg tggttattga taaagacttg gttgaactgt tgcacctgtc ctggcaaagt
    16441 atgcccgttc aagctgtatt ccttgacacg agggaaggct tggtcaatta ctgccttaag
    16501 taccttagac tggatcgtat cataagtcac cttgctatcg tcaacaaccg aacctgtttc
    16561 tttctgggca ggagtatcat ccgcttttac gccttcttga ttgtctgttt taacgctgac
    16621 aaccgtacgg tcattgccat aagagcccgc cttgagaagg atcttcttct catttttaag
    16681 atggtcattg accgcagctg gtagagtcac tgtgtcaaag agattgacat cgttattgct
    16741 ggcatttagc tgaccgtctg acttgagagt gatagagaga cggtttgttg atcctgtttc
    16801 aggagcagca acacgactac ctctatacca agtgctagtt gttggagatt tatactccca
    16861 gaaccagcca tccttgtcat aaccgacaaa aacattatta ttggtatctt taaatttcag
    16921 gaagacacca aagcgtgatt tgcccttttc agaatcatct ttgaaggtta aatcaacagt
    16981 tgcatttcca ttggcatcaa cggtcaagcc cttcttttca aacagggctg gtttacctgc
    17041 gttatcattt tgagcagttg aggatagttg gttgtagcgg acaccttttt cttctcggat
    17101 agtgactgtt cccttttgtt cttttttctc taccgtttgc cattcagggg ttaccgtctt
    17161 aggtgtttca ggtttagcag ctgcaggttt atcctctttt ggtttttctt cagccggttt
    17221 ttctttttca agtgctaata gttcttcttc tgtcttaggt ccatctgtaa cttctggaga
    17281 accttggtct tctcccacct taggcgcttc aaaatcacgt ccatcattct cttttgctgt
    17341 tgcaagagca gtagctaaat cagctggtaa gttcgccgtg gaaccagact gcacgctatc
    17401 tgcaagaacc ggacttgtcc caaagaatgc agctccaatc ataacagaag caacacctaa
    17461 tgaaaatttc cgaatactat atttacaacg tttttcaaat aatcctttat tcataaactt
    17521 ctaaatcctt tcatttttta gcaagcgttt acatttcctt tttaaaaaat actccttcct
    17581 ctgaaagtgc aatgcttaac cctgataaat aaaaaataat tatactttta atataacaaa
    17641 taatagctga gaaagcaata ggaaacaagt aaaattaaca aaaattttct ctattctgac
    17701 aaaaagaggc tccaactttt gggggtcagt acatttagaa tctttcttta caaatgtaaa
    17761 aaaggattca gcattcaaga gaaatactaa atcctttctt atattttgca acagttattt
    17821 cacatgtttt gcgagatctt cttgagcctt tttattagac tcttcttttt ctttcatcca
    17881 tttttcctga gctttttggt attcatctac agtgactgcc ttgtcttgaa gttccaagta
    17941 tttatacaag actggttcac ttgtaccttt atttcctgac aatgcaaatg gtattgtaaa
    18001 tggtaccatc ttagacaaga ttgggcgccc tgtacgagat gtagttggaa taatcaaagc
    18061 actatctgtc aaccaagctt gggctgcagc gtatttatca tagcgtttag caacatctgt
    18121 agtctcatca ccagcctcag taaccaattt ttcgtagtca tatagaccta cttttttagc
    18181 agctacatta tcttcccctg agtcaaaccc taaatatgtt ttagtacttt ctcctacaga
    18241 tggtttgatg atatcaaggt aggttgatgg atcggcaaag tctggacccc aaccgacatt
    18301 atctgataaa tcccagtctt cgccagcagc attttcagca aaatatgtaa tattgtttac
    18361 ttcgtctttt tgtagttgtt gaatatcaat gactacatta tccgctccta aagttgcttc
    18421 caaggattgt ttcatagatt ggacgcgctg aacttttgta gttgctgttt ggtcaactgg
    18481 catatccaaa tgaattggga atgtcacacc ttctgcttgt aaggctgatt tagctttagc
    18541 aaattcagcc ttggattttt ctggattgta aagaccatcc tgagaatctg caagattaac
    18601 atccttccat tcatccccat aagtaaccaa tttctctttg accatatcgc caaagttttt
    18661 accatctgct tgaacaaatg ttggtggaac aaagatatta cgtaagattt tgcttgctcc
    18721 agtttgtcca ttcaactgag aggcataggc tgtacgatca aaaccaaagg caatagcctg
    18781 acggaaatcc ttgtttaaga gagccttttt agtcgatgcc ttttgttcgt cgctggtctt
    18841 agatgtgtat ttataggact gacggtcaat atttgtacca actagatacg taatagagtc
    18901 ttgttgagta tagacaatat tgtccttcat actcttctca agctctgcga aacttgcact
    18961 tgttggatag agacgagctg ctgtaaggct accatcttta aagttttctg caggtttgct
    19021 ggtatcttga ccatcccaga atgacaattt aactttgtca atatgcacat tgtccttatc
    19081 ccagtagttc ggatttttcg caaattcaac agaagatttg gtcacaatgg atttcaacaa
    19141 ataaggtcca ttatacaaga gactacttgg atccgtagct ttggcaaaat catccccttt
    19201 tgagttcaaa aactcttcat taactggcgc aagcacaccc atggttgttt ttgagttcca
    19261 aaaactttca ggtttgttca aagtgtactg aactgtctga tcatccagag ccttaattcc
    19321 tacttgtgag aaatctttga tttccccttt tacataggca tccaaccctt tgattgattc
    19381 ttgaacaagg taaagagcat ctgatttttt atcagcagca tattttagtc ctgttacaaa
    19441 gtcttgagct ttgactgccg cgtattcttc accttcagaa gtataccatt ttgcatcctt
    19501 acggatagta taagtgtaag tcaatccatc cttggataca gaccaatcct cagccataga
    19561 cggcacaaag ttcccgtagc gatcattttc tagcaaacca tcaaccacgt tactggtaat
    19621 atttgctgtc gcagccttag cagttgtcaa atagttgagg ttatcagggt ctgtctcata
    19681 aatgtatgag aatgtcttct cacctttagt gcttgaacct gatccagagc atgcagctaa
    19741 agtagtcgcc gccaataatg tcacgcccgc aagggcaaat agtcttgaac ttttcatcat
    19801 tttctccttt aaaactttct ctccattata gactcttttc agaaagttgt caacagaatt
    19861 ttcagaattt ttgtgttaat ttggtatatt ctgaaaagac aaaaaaggag aagacagtga
    19921 ttgtcctctc cagatgttag ttgacaaaga gccacattat aaatctaaaa taatttattt
    19981 taatttaata tacttttgtg gtaataaaac aatattcaaa aatggaattt ttttcaatat
    20041 ataagttgcc agtatggata aataccaacc caagacaatc ccaacaacaa cgtgaagaaa
    20101 aactgagttt attcccactt tcaacattta ggatttttat agatatttat taaatcaaat
    20161 atagtcgtcg ggactctaac agtcgcccct gcaacttttt gaagaccaaa gtgaatgatc
    20221 gaatagaaaa tatatggcag accaaaaaca attgtcttct ttttagcata ttgccagaac
    20281 tccttcaaat ccgacacagg tttgaaaaag tatcctgata aggcaaaaaa tactggtata
    20341 tgaaatatgt agacttgtgc tatcaacaac gatagtatgt tatttgctgt gggaaatttt
    20401 tccgattgat acagtccaag caacacatgt cctgctaaga ctaaaaatat ggaaaagcct
    20461 tttccaaaat ctatccaatt gattctactt tttgtcatat ccaaactctt tctccacaac
    20521 ctcaagcgcc cgttcaatca ccacatgcat atcgtaatat ttataatctg ctaaacgtcc
    20581 acagaaaata accttatcat tctttgaagc ttcctcttgg tacttagcaa acatagcatt
    20641 atttttctca tcgttgatcg gatagtaagg ctcgtcccca cgcttccagt cagctggata
    20701 ttcacgcgtg ataactgtct ttgcctgtgt tccatattca aaatgcttgt gttcgataat
    20761 acgagtataa ggaatctcac gctccgtata gttcactaca gcatttcctt gataattttc
    20821 ctcgtccaaa atttcatgat caaagcgaag gctacggtat tctaactctc cgtgcttgta
    20881 gccaaaatac tggtcgatca tccctgtaaa gacaactttt tcagctgatg cttctaactc
    20941 ttcacgatga gcaaagaaat caacaccaag ctcaacttca acgtctttaa gcatattttc
    21001 gatgatgaca ttgtaaccac caataggaat tccttggtaa cggtcgttaa aatagttatt
    21061 atcaaatgtt aaacgaactg gaagacgttt aatgataaat ggaggaagtt ccgttgctga
    21121 gcgtccccac tgcttttcag tataaccctt gattaacttt tcatagacat ctggaccaat
    21181 caacttgata gcctgttctt ccagattttt cggctcaaca tccttcatat cagctgtctg
    21241 ctcagtaatc ttatctttga cttcttgagg agtttttgtc ccccacatag catagaaggt
    21301 attcatattg aaaggtagat tatagaggct acccttgtaa ttagctacag gcgagttgac
    21361 gtagttgtta aattcagcaa attgattaac ataatcccaa actttcttat tagaagtatg
    21421 aaagatatgg gcaccatatt tatgaacatt aactccttct acattctcac agtagatatt
    21481 cccaccaatg tggttacgtt tatcaatcac ttttactttt tttccacgct tggtcgcctc
    21541 ataagcaaaa attgctcctg acaaaccagc accgacaata agataatcgt acatcttgtt
    21601 ctccttttta taatttgacg attcgattga agtaaggaat cttcattaac atcccaacaa
    21661 taataaaact aacacttaaa gtaaatagag caaaaagtaa atatgctcct acaaaattaa
    21721 aaccaagcac tttttcccac actttcataa tataagtatg tattatgaaa acccccattg
    21781 tttgattaga aagggaaaca atcgattctc ttcggttttc attcaaagta agcatgagga
    21841 tagttagaaa aattcctaaa gtactgactt ttacaaataa agtatcataa aagtattcag
    21901 caaatagatt atggtatata gtcttcgcta tgaaaaataa tattattggt gaaatcaata
    21961 acaaaagtat gctaactatt ttcatccaat tcttaaacct tgattcgatt tcttctatag
    22021 tgaattgcgc tatataacca cctaaaagat agtaaaaaaa ccacgtccat aatctaaaag
    22081 tttgtattac atatgtttg
//
LOCUS       DAVMCN010000029        21433 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVMCN010000029 DAVMCN010000000
VERSION     DAVMCN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.029"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            98..2320
                     /gene="recJ"
                     /locus_tag="VYP85_001277"
     CDS             98..2320
                     /gene="recJ"
                     /locus_tag="VYP85_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1881795.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            2495..4156
                     /locus_tag="VYP85_001278"
     CDS             2495..4156
                     /locus_tag="VYP85_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1881796.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFIPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            4225..5004
                     /locus_tag="VYP85_001279"
     CDS             4225..5004
                     /locus_tag="VYP85_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1881797.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            5116..6336
                     /gene="murM"
                     /locus_tag="VYP85_001280"
     CDS             5116..6336
                     /gene="murM"
                     /locus_tag="VYP85_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1881798.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            6341..7573
                     /gene="murN"
                     /locus_tag="VYP85_001281"
     CDS             6341..7573
                     /gene="murN"
                     /locus_tag="VYP85_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1881799.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            7652..8353
                     /locus_tag="VYP85_001282"
     CDS             7652..8353
                     /locus_tag="VYP85_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1881800.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            8393..10240
                     /gene="uvrC"
                     /locus_tag="VYP85_001283"
     CDS             8393..10240
                     /gene="uvrC"
                     /locus_tag="VYP85_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1881801.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            10230..11063
                     /locus_tag="VYP85_001284"
     CDS             10230..11063
                     /locus_tag="VYP85_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1881802.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWDDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11245..12045)
                     /locus_tag="VYP85_001285"
     CDS             complement(11245..12045)
                     /locus_tag="VYP85_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1881803.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            12216..12821
                     /locus_tag="VYP85_001286"
     CDS             12216..12821
                     /locus_tag="VYP85_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1881804.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            12834..14234
                     /gene="pepV"
                     /locus_tag="VYP85_001287"
     CDS             12834..14234
                     /gene="pepV"
                     /locus_tag="VYP85_001287"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1881805.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            14288..14866
                     /locus_tag="VYP85_001288"
     CDS             14288..14866
                     /locus_tag="VYP85_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1881806.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            15026..15178
                     /locus_tag="VYP85_001289"
     CDS             15026..15178
                     /locus_tag="VYP85_001289"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1881807.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGARNLPLSQ
                     LADSYD"
     gene            15221..15313
                     /locus_tag="VYP85_001290"
     CDS             15221..15313
                     /locus_tag="VYP85_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1881808.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLVFEEL"
     gene            15484..16809
                     /gene="brnQ"
                     /locus_tag="VYP85_001291"
     CDS             15484..16809
                     /gene="brnQ"
                     /locus_tag="VYP85_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1881809.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVMVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            16907..17944
                     /locus_tag="VYP85_001292"
     CDS             16907..17944
                     /locus_tag="VYP85_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1881810.1"
                     /translation="MNQTVKYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEEHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVSNEKETRALGIEVG
                     DFISFDPRTVVTEAGFIKSRHLDDKVSAAILLNLLLIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            17946..18416
                     /locus_tag="VYP85_001293"
     CDS             17946..18416
                     /locus_tag="VYP85_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1881811.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLVQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETCQAKSDEIKQLVKRLSSELDKLLEIKE"
     gene            18419..19135
                     /locus_tag="VYP85_001294"
     CDS             18419..19135
                     /locus_tag="VYP85_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1881812.1"
                     /translation="MKKRYLVLTALLTLSLAACSQEKAKNEDGEAKTEQTAKTDGTVG
                     SKSQGTAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            19399..19824
                     /gene="rplK"
                     /locus_tag="VYP85_001295"
     CDS             19399..19824
                     /gene="rplK"
                     /locus_tag="VYP85_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1881813.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            20032..20721
                     /gene="rplA"
                     /locus_tag="VYP85_001296"
     CDS             20032..20721
                     /gene="rplA"
                     /locus_tag="VYP85_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1881814.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            21099..21236
                     /locus_tag="VYP85_001297"
                     /pseudo
     CDS             21099..21236
                     /locus_tag="VYP85_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         6403 a         3980 c         4980 g         6070 t
ORIGIN      
        1 tactataaaa tgttataaaa aagcaatctg gatagagaaa acgtctaaat catgttataa
       61 tgaagcaata gaattcttag aaagagtgga tgtctttttg ataacaccta cttatgaatg
      121 gcagtttgcc ctgcaggtag aagatgcgga ttttacaaag atagccaaga aggctggact
      181 gggtcctgag gtggctcggt tattgtttga gagagggatt caggaccaag aaagtctgaa
      241 gaagttttta gaaccttcct tggaggactt acatgatgct tatctgctcc atgatatgga
      301 caaggcagtg gagcggattc gtcaggctat tgaagaaggg gaaaatattc tcgtttatgg
      361 agactatgat gcggatggca tgacttcggc ttctattgtg aaggaaagtt tggaacaact
      421 tggtgctgag tgccgagttt acctgccaaa tcgttttacc gatggctatg gccctaatgc
      481 tagtgtttat aaatacttta tcgagcaaga aggaatttcc ttgattgtga cggtggacaa
      541 tggggttgct ggtcatgagg ctattgcatt ggctcagtct atgggagtag atgtcattgt
      601 gacagaccat cattccatgc ctgaaaccct gccagatgct tatgctattg tccatcctga
      661 acatccagat gcggattatc cttttaaata tttggctggt tgtggagttg ctttcaagtt
      721 ggcttgtgcc ctgttagaag aagtgcaagt ggaattgctt gatttggtcg ctattggaac
      781 tattgcagat atggtgagtc tgacggatga aaatcgtatc ttagttcaat atggtctgga
      841 aatgttgggt catacccagc gcattggtct gcaagaaatg ctggacatgg ctgggattgc
      901 tgccaacgaa gtaacagaag aaacggttgg tttccagatt gctcctcgtt tgaatgcctt
      961 gggtcgcttg gatgatccca atcctgccat tgatttgttg actggatttg atgatgagga
     1021 agcgcatgag attgccttta tgattcacca gaaaaacgaa gagcgcaagg aaatcgttca
     1081 gtctatctat gaagaagcca agaccatggt ggatcctgag aagaaggttc aggtcttggc
     1141 caaggaaggc tggaatcctg gggttctagg aatcgtggct ggtcgtttat tggaagaatt
     1201 gggacagaca gtcattgttc ttaatataga agacggtcgt gccaagggca gtgctcgtag
     1261 tgtggaagcg gtcgatattt ttgaagctct ggatccccat cgagacctct ttatcgcctt
     1321 tggaggtcat gcaggtgcag cgggtatgac gctggaagtt gagcaactct cagatttatc
     1381 tcaggttttg gaagattatg ttcgtgaaaa aggtgcagat gctggtggca agaataagtt
     1441 aaacctagat gaagagttgg atttggaggc acttagcttg gaaacggtca aaagttttga
     1501 acgtttagct ccttttggaa tggataatca gaaacctatt ttttatatca agaattttca
     1561 ggtcgaaagt gctcgtacta tgggggcagg taatgcccat ctaaagctga aaatttccaa
     1621 gggtgaggcg agttttgaag tggtagcctt tggtcaaggc agatgggcga cagagttttc
     1681 tcaaaccaag aatctagagt tagcggttaa attgtctgtc aaccaatgga atggccaaac
     1741 tgccctccag ttgatgatgg tggatgcgcg agtggaaggt gttcaacttt ttaacattcg
     1801 tggaaaaaat gcagtcttgc cagaaggtgt tccagtcttg gattttcctg gagaactgcc
     1861 aaatcttgcg gctagtgaag ctattgtcgt aaaaaacatt ccagaggata ttactcagct
     1921 gaagaccatt tttcaggaac agcatttctc tgctgtctat ttcaaaaatg atattgacaa
     1981 ggcctattat ctgacaggtt atgggactag agatcagttt gccaaattgt acaagactat
     2041 ttaccagttc ccagagtttg atattcgcta caagctgaaa gatttggctg catatcttaa
     2101 tattcaacaa atcttgctgg tcaagatgat tcaagtattt gaagaactag gctttgtgac
     2161 gataaaagat ggtgtgatga cagtcaataa agaggcgcca aagcgggaga taggagaaag
     2221 tcaaatttac caaaatctca aacaaaccgt taaagaccaa gaaatgatgg cgctgggtac
     2281 ggtgcaagaa atttatgatt ttttgatgga aaaagagtag aagttaggaa agagttggga
     2341 aatcaactct tttttgaaaa cagaccttca ttttgaaaat catcaaaaaa atggtataat
     2401 ggtaggaaaa gattcggctg aaagtatcag aacttttaga ataagagggt agaattgccc
     2461 tataatcaag ataaactaag attttggagg aaaaatgagt aatatcagtt taacaacact
     2521 tggtggtgtg cgtgagaatg gaaaaaatat gtacattgct gaaattggag agtccatttt
     2581 tgttttgaat gtagggttaa aatatcctga aaatgaacaa ttaggggtcg atgtggtgat
     2641 tccaaacatg gattaccttt ttgaaaatag cgaccgtatt gctggggttt tcttgaccca
     2701 cgggcatgcg gatgccattg gtgctctacc gtatctcttg gcagaggcta aagttcctgt
     2761 atttgggtct gagttgacca ttgagttggc aaagctcttt gtcaaaggaa atgatgccgt
     2821 taagaaattt aatgatttcc atgtcattga tgagaatacg gagattgatt ttggtgggac
     2881 agtggtttcc ttcttcccta cgacttactc cgttccagag agtctgggaa ttgtcttgaa
     2941 gacatcggaa ggaagcatcg tttatacagg tgacttcaaa tttgaccaaa cggctagtga
     3001 atcttatgca actgattttg ctcgtttggc agagattggt cgtgacggcg tcctggctct
     3061 cctcagtgat tcggccaatg cagacagcaa tattcaggtg gctagtgaaa gtgaagttag
     3121 ggatgaaatt acccaaacta ttgctgactg ggaaggtcgt atcatcgttg cagctgtttc
     3181 cagtaatctt tctcgtattc agcagatttt tgacgctgcg gataaaacag gtcgacgtat
     3241 cgtcttgaca ggatttgata ttgaaaatat cgtccgcaca gcgattcgtc ttaagaagtt
     3301 gtctttagcc aacgaaattc ttttgattaa gcctaaagat atgtctcgct ttgaagacca
     3361 tgagttgatt attcttgaga caggtcgtat gggtgagcct atcaatggac ttcgtaagat
     3421 gtcgattggt cgccatcgtt atgtagaaat caaggatggg gacctagtct atattgctac
     3481 ggctccgtct attgctaaag aagcctttgt tgcgcgtgtg gaaaatatga tttatcaggc
     3541 aggtggggtt gtcaaattga ttacccaaag tttacatgta tcagggcacg gaaatgtgcg
     3601 tgatttgcag ctgatgatca atcttttgca acctaagtac ctcttccctg tccaagggga
     3661 gtatcgtgag ttggatgctc acgctaaggc tgccatggca gttgggatgt tgccagaacg
     3721 catcttcatt cctaaaaagg ggacgaccat ggcttacgag aatggagact tcattccagc
     3781 tggatcggtt tcagcaggag atatcttgat tgatgggaat gccattggtg atgttggaaa
     3841 tgttgttctt cgtgaccgta aggtcttgtc agaggatgga attttcatcg tggctattac
     3901 agtcaaccgt cgtgagaaga aaattgtggc tagggctcgt gttcacacgc gtggatttgt
     3961 ttatctcaag aagagtcgcg atattctccg tgaaagttca gaattgatta accaaacggt
     4021 agaagagtat cttcaaggag atgactttga ctgggcagat ctcaaaggta aggttcgtga
     4081 caatctgacc aagtacctct ttgatcaaac caagcgtcgc ccagccattt taccagtagt
     4141 catggaagca aaataatcgt tgaaataaac agagagaaag tcgagtttcg gctttttctt
     4201 atagaaaaat agaaggagaa aatcatggca gtaatgaaaa tcgagtatta ctcacaagta
     4261 ttggatatgg agtggggggt gaatgtcctc taccctgatg ccaatcgagt ggaagaacca
     4321 gagtgtgaag atattcccgt cttgtacctt ttgcacggga tgtctggaaa tcataatagt
     4381 tggcttaagc ggaccaatgt agaacgcttg cttcgaggaa ctaatctcat cgttgttatg
     4441 cccaatacca gcaatggttg gtacaccgat acccagtatg gttttgacta ctacacggct
     4501 ctagcagagg aattgccaca ggttctgaaa cgcttcttcc ctaatatgac gagcaagcgt
     4561 gaaaagacct ttatcgctgg tctttctatg ggaggctacg gctgcttcaa actggctctt
     4621 acgacaaatc gtttttctca tgcagctagt ttttcaggtg ccctcagctt tcaaaacttt
     4681 tctcctgaaa gtcaaaatct gggaagtcca gcctactgga gaggtgtttt tggagagatt
     4741 agagactgga caactagtcc ctattctctt gaaagtctgg ctaaaaaatc ggataaaaag
     4801 accaaacttt gggcgtggtg tggcgaacag gatttcttgt acgaagccaa taatctcgca
     4861 gtgaaaaatc tcaaaaaact aggttttgat gtgacctata gccatagcgc tggaactcac
     4921 gagtggtact actgggaaaa acaattggaa gtttttttaa caaccctacc aattgatttc
     4981 aaattagaag agagactgac ttagtttgaa cttcagcata gggggagtag aactaaaata
     5041 aaatatgttt tcactagact tttcaaacga aagtagtaga atagtaataa aatactggag
     5101 gaaagagagt aggaaatgta ccgttatcaa attggcattc ccacattaga atatgatcag
     5161 tttgtcaaag aacatgaatt agccaatgta ttacaaagta gtgcttggga ggaagttaag
     5221 tctaattggc aacatgagaa gtttggtgtt tacagggaag aaaaattact ggcgacagct
     5281 agtattttga ttagaactct tccgctaggc tataaaatgt tttacatccc aagaggacct
     5341 atattggatt atggggataa agaactcttg aattttgcca ttcagtctat taagtcctat
     5401 gctcgcagta agagagtggt ttttgtgact tttgacccaa gtatttgcct atctcaaagt
     5461 ttaatcaatc aggaaaagac agaatttcct gaaaatctgg ctattattga tagtttgcaa
     5521 caaatgggag taaggtggtc aggaaaaacg gaggaaatgg gagacaccat tcaacctcgt
     5581 attcaggcga aaatatacaa ggaaaatttt gaagaagata aactttccaa gtcaacaaaa
     5641 caggctattc gaacagcacg aaacaaaggg cttgagattc aatatggtgg actggaacta
     5701 ttagattcat tttcggagtt gatgaaaaaa actgagaagc gaaaagagat tcatttgagg
     5761 aatgaagcct attataaaaa attgttagat aattttaagg acaaggccta tatcaccttg
     5821 gccaccttgg atgtttctaa acgttcgcaa gagttagaag aacagttagc gaaaaataga
     5881 gccttggaag agacctttac tgagtcgact cgaacttcaa aagtagaagc gcagaagaag
     5941 gaaaaagaac gtttgttaga ggaattgacc ttcttgcagg aatatataga tgtaggtcaa
     6001 gcgagagttc ctttagcggc tactttgagt ttggaatttg gtactacctc tgtcaatata
     6061 tatgctggta tggatgatga ttttaaacgt tacaatgcac caattttaac ttggtatgaa
     6121 acggctcgct atgcctttga acgaggtatg atctggcaaa atttaggtgg tgttgaaaac
     6181 tctctcaatg gtggacttta tcattttaag gaaaaattta atccaacgat tgaagaatac
     6241 ttgggtgaat ttacaatgcc cactcatcct ctctatcctc tgttaagact tgctcttgat
     6301 ttccgtaaaa cattaagaaa aaaacataga aagtaagtat atggcactaa caacactcac
     6361 gaaagaagag tttcagactt attctgatca ggtttcttct cgttccttta tgcaatctgt
     6421 ccagatgggg gatttgctag aaaaaagagg ggctcgaatt gtttatcttg ctttgaaaca
     6481 agaaggagaa attcaagttg cagctctggt ttatagcttg cccatgctgg gtggtctgca
     6541 tatggaactc aattcggggc cgatttatac ccaacaagat gctcttccag ttttttatgc
     6601 agagttaaaa gaatatgcca agcaaaatgg tgtattagag ttgcttgtaa aaccttatga
     6661 aacttatcaa acttttgata gccaaggtaa tccaatagat gctgagaaaa aaagtattat
     6721 tcaaggtttg actgatttag gttatcaatt tgatggctta acaacaggtt acccaggtgg
     6781 agaaccagat tggttatact ataaagattt aactgaatta actgaaaaga gtttgcttaa
     6841 aagttttagc aaaaagggta aacccttggt gaaaaaggct gaaacctttg gcattcggtt
     6901 gaaaaagtta aaacgtgaag aactatcgat ttttaagaat ataacaaaag aaacctctga
     6961 acgtagagaa tatagtgata aaagtttaga atattatgag catttttatg atacttttgg
     7021 agaacaagcg gagtttctca tagcaagctt aaatttttcg gactatatga gcaaattgca
     7081 aggtgaacaa agtaaactag aagaaaactt ggacaagttg cgacttgatt tgagtaaaaa
     7141 tcctcattct gagaaaaaac aaaatcaact gagagaatat tctagtcaat ttgaaacgtt
     7201 tgaagttcga aaagcagaag cgcgagactt gattgaaaaa tatggagaag aagatattgt
     7261 tttagctggg agtttatttg tttatatgcc tcaggaaacg acttatctct ttagtggttc
     7321 ctacactgag tttaataagt tctatgcccc tgccctgctt caaaaatatg ttatgttgga
     7381 aagcataaaa cgtggaatac ctaaatacaa cttcctaggc attcaaggga tttttgatgg
     7441 aagtgatggt gttttgcgtt ttaaacagaa ttttaatggc tatattgtac gcaaagcggg
     7501 tactttccgt taccatccat cgcctttaaa atacaaagct atccagttac tcaaaaaaat
     7561 agtaggacgt taagatgaaa aagtcagtat ttagatttct tttagcttct tttagtaaaa
     7621 taattcttat ttgctagaaa ggtggagaga catgcgctgg ctttttcgtt tgataggggc
     7681 tttcttttct tttgtgtggc gtttgttttg gcgtctggtt tggatagttg tgctcttatg
     7741 tgtgcttgct ttcggacttc tctggtatct gaacggggat tttcaaggag cgctaaagca
     7801 agcagaacgg tcagtaaaaa ttggtcaaca aagtattgac caatgggaga aaacagggca
     7861 actgcctaag ttaagccaga cagatagtca ccagcattct gaaggaaggt gggcacaggc
     7921 ctctgctcgt atttacctgg atccgcagat ggattcacgc tttcaagagg cttatttaga
     7981 agcaatccag aactggaatc aaactggtgc ttttaacttt gaactcgtga ctgagtctag
     8041 taaggcggat attacggcta cggagatgaa cgacggaggc actcctgtgg caggagaggc
     8101 ggaaagtcaa actaatctct taacagggca attcttgtcc gtaacggtgc ggttgaatca
     8161 ttattatttg tccaatccat actatggcta ctcctatgaa cgccttgtcc atacggcaga
     8221 acatgagtta ggtcatgcga ttggcttgga ccatacagat gagaagtctg tcatgcaacc
     8281 agcaggttcc ttttatggta tccaggaaga ggatgttgca aacctccgaa aaatatatga
     8341 gactagtgag tagggtacta tctttcccta ctttttttgc tataatggaa ctatgaacaa
     8401 cttgattaaa tcaaaactag agctcttgcc gaccagccct ggttgctaca ttcataagga
     8461 taaaaatggc accattatct atgtaggaaa ggctaaaaat ctgcgtaatc gagtacggtc
     8521 ctattttcgt ggaagtcatg ataccaagac agaggctctg gtgtctgaaa ttgtggattt
     8581 tgaatttatt gttacggagt ctaatattga ggcacttctc ctagaaatca acctgatcaa
     8641 ggaaaacaag cccaagtaca atatcatgct caaggatgac aagtcctatc ctttcatcaa
     8701 aatcaccaat gagcgctatc cacgcttgat tatcactcgt caggtcaaaa aggacggagg
     8761 tctttatttt ggaccctatc ccgatgtggg ggcagccaat gaaatcaagc ggttgctgga
     8821 tcggatattc ccttttcgta agtgtaccaa cccgccctct aaggtctgtt tttattacca
     8881 tatcggccag tgtatggctc acaccatctg taagaaggat gaggcttatt tcaagtctat
     8941 ggcccaggag gtttctgatt ttctgaaagg gcaggataac aaaatcattg atgagctaaa
     9001 gggcaaaatg gcagcggcag cccagactat ggagtttgaa cgtgcggcgg aataccgtga
     9061 cctgattcag gctattggaa cgcttcgaac caagcaacgg gtcatggcta aggatctcca
     9121 aaatcgcgat gtctttggct actatgtgga taagggctgg atgtgtgtgc aggttttctt
     9181 tgttcgtcag ggaaagctca tcgagcgcga tgtcaatctc ttcccttact tcaatgatcc
     9241 agatgaggat ttcttgacct atgtgggaca attctatcaa gaaaaatctc acctagttcc
     9301 caatgaggta ctgattccgc aggatattga cgaagaagct gtcaaggctt tggtggatac
     9361 caagattctc aaaccccaac gtggagagaa aaaacagctg gtcaatctag ccataaaaaa
     9421 tgcacgtgtt agtctggagc agaaatttaa cctgctagaa aaatcagtcg aaaagaccca
     9481 aggagctatt gaaaatctag gacgtttgct ccaaattccg actccagttc gcatcgagtc
     9541 cttcgataac tccaacatca tggggaccag tcctgtttca gccatggtgg tctttgttaa
     9601 cggcaggcca agtaaaaaag attaccgtaa gtacaagata aaaaccgttg ttgggccgga
     9661 cgactatgct agtatgagag aagtcattcg aagacgctat ggtcgagtac agcgtgaggc
     9721 tttgactcct ccagatttga ttgtgattga tggggggcaa ggtcaagtca atattgctaa
     9781 gcaagtcatc caagaagaac tgggcttgga tattccaatt gcaggtctgc aaaagaatga
     9841 taagcaccaa acccatgaat tgctctttgg agatccgctg gaagtggtgg acttgtctcg
     9901 caattctcag gaatttttcc tcctccaacg cattcaagat gaggtccacc gctttgccat
     9961 taccttccac cgccaactgc gctccaaaaa ttctttctca tctcaattgg atgggattga
    10021 tggtctggga cctaaacgca agcaaaatct catgaggcac ttcaagtctc tgaccaaaat
    10081 caaggaagcc agtgtggatg agattgtcga agttggagta ccaagagcag tagcagaggc
    10141 tgtgcaaaga aagttgaacc cgcaggaaac agaaatcttg cttcaagtgg cggaagaaag
    10201 agtagattac caaacggaag gaaaccacaa taaaccataa aatcgcaatt ttatcagata
    10261 ttcatggcaa tgcgacggcg ctagaagcag tgattgcaga tgctaaaact caaggagcca
    10321 gtgaatattg gctcatggga gacattttcc tccctggttc aggtgcaaat gacttggtcg
    10381 ctctgttaaa ggaacttcct atcacggcaa gtgttcgagg caattgggat gattgtgtcc
    10441 ttgaggcttt agatgggcaa tatggcttag aagacccaca ggaaatccag ctcatgcgaa
    10501 tgactcagtt tttgatggag cgaatggatc ctgcaacgac tgtctggcta cgaagcttgc
    10561 ctttgctgga aaagaaagaa attgctggac tgcgcttttc tatctctcat aatttgccaa
    10621 ataagaacta tggtggtgac ttgctagttg agaatgatac agagaaattt gaccaactgc
    10681 tagatgcgga aacggacgtg gcagtttatg gtcatgttca caagcagttg cttcgttatg
    10741 gaagtcaagg gcaacaaatc atcaatccag ggtcgattgg catgccctat tttaattggg
    10801 aggcgttaaa aaatcaccgt gcccagtatg ccgtgataga agttgaagat ggggaattgg
    10861 tcaatatcca atttcgtaaa gttgcttatg attacgaggc tgagttagaa ttggccaagt
    10921 ccaaggggct tccctttatc gaaatgtatg aagaactgcg tcgtgacgat aactatcagg
    10981 ggcacaatct ggaattatta gccagcttaa tagaaaagca tgggtatgta gaggatgtga
    11041 agaatttttt tgattttttg taagagtttc ctaaaatagc caatgcaaac taaaaaagcg
    11101 attggctggt ccaatcgctt ttagtatatc ttatactcaa tgaaaatcaa agagcaaact
    11161 aggaagctag ccgtaggttg ctcaaagcac agctttgagg ttgcagataa agctgacgtg
    11221 gtttgaagag attttcgaag agtgttattg taactgagat tgatctggga ggtaagaacc
    11281 acctagatag gtattgctga gtttttcaag ggttccgtct tgatagagtt ctttgagcgc
    11341 tttatcaaat tgctctttaa actctttttg gtcgcttgag aaaatgatat aattgctggg
    11401 gctatctgca gaaggtaaat caacgactga gaggtctaaa ccacggtcct tgataatctt
    11461 ttgaacggat accttgtcaa aaactaggaa atcaaactct ccgttagcaa ggtctaggat
    11521 tcgtttacca atatcctcac cagaaaaatt aattgtagcg ggattatcag tgtgtttctg
    11581 attccagtta ttgatgaatt gagcgttaga agttccggta tcctcttgtg ttgttttacc
    11641 agcgatctgg tcaagagaag tcaaaggatt tttcttgttg ctgacaagga cgaggggatt
    11701 gttggaaatt ggaagcgagt aaaggtattt ttcagcacgc tcttttgtgt aactcaagtt
    11761 attggccgca gcctgatagt gaccagaatc aagtcctggg aagatgctct cccaggcggt
    11821 tctttggaat tgaatctcgt agtcgctgag tttttcatct actgccttta aaacttcgat
    11881 atcgaagcct gtcagattgc ccttgtcttc gtagtcaaat ggtggcacgt cgccagctgt
    11941 agcaaggacg attgtctttt gagcgctagt ctctttgggt gtagcttgat tcccacaggc
    12001 aaccaaaaat ggtaggatag ctagtaatag gctaaatttt ttcatactgt ctccattcaa
    12061 atgtaaagta cttgctagtt tatcagaaac tttcctgata aaccaatata tatcttttat
    12121 gtctgtgata gaaaaactta atcatgaaaa atccctgcaa gctctttcaa attatggtag
    12181 aatggaagca gtagaattag aaaaggaaat cgattatgaa atttcttgaa ttaaataaaa
    12241 aacgtcatgc gactaagcat tttactgata agcctgttga tcccaaagat gtgcgtacgg
    12301 ctatcgaaat tgcaaccttg gcgccaagcg cccacaacag ccagccttgg aaatttgtgg
    12361 tggtacgtga gaaaaatgct gaactggcaa agttagctta tggttccaat tttgaacagg
    12421 tatcatcagc gcctgtaacc attgccttgt ttacagatac ggacttagcc aaacgtgctc
    12481 gtaagattgc ccgtgttggt ggtgctaata acttttctga agagcaactt caatatttta
    12541 tgaaaaatct gccagctgag tttgcccgtt acagtgagca acaagtcagc gactacctag
    12601 ctctcaatgc aggtttggtt gccatgaact tggttcttgc attgacagac caaggaattg
    12661 gttctaacat tattcttggt tttgacaaat caaaagttaa tgaagttttg gaaatcgaag
    12721 accgtttccg cccagaactc ttgatcacag tgggttatac agacgaaaaa ttggaaccaa
    12781 gctaccgctt gccagtagat gaaatcatcg agaaaagata gaaagaagaa aaaatgacag
    12841 caattgattt tacagcagaa gtagaaaaac gcaaagaaga cctcttggct gacttgttta
    12901 gccttttgga aatcaattca gaacgtgatg acagcaaggc tgatgcccag catccatttg
    12961 ggcctggtcc agtaaaagcc ttggagaaat tccttgaaat cgcagaccgc gatggctacc
    13021 caactaagaa tgttgataac tatgcaggac attttgagtt tggtgatgga gaagaagttc
    13081 tcggaatctt tgcccatatg gatgtggtgc ctgctggtag cggttgggac acagaccctt
    13141 acacaccaac tatcaaagat ggtcgccttt atgcgcgcgg ggcttcggac gataagggtc
    13201 ctacaacagc ttgttactat ggtttgaaaa tcatcaaaga attgggtctt ccaacttcta
    13261 agaaagttcg cttcatcgtt ggaacagacg aagaatcagg ctgggcagac atggactact
    13321 actttgagca cgtaggactt gccaaaccag atttcggttt ctcaccagat gctgaatttc
    13381 caatcatcaa tggtgaaaaa ggaaatatca cggaatacct ccactttgca ggagaaaata
    13441 caggtgttgc ccgtcttcac agctttacag gtggtttacg tgaaaatatg gtaccagaat
    13501 cagcaacagc agtcgtttca ggtgacttgg ctgacttgca agctaaacta gatgcctttg
    13561 ttgcagaaca caaacttaga ggagaactcc aagaagaagc tggcaaatac aaggtgacga
    13621 tcattggtaa atcagcccac ggtgctatgc ctgcttcagg tgtcaatggc gcaacttacc
    13681 ttgccctctt cctcagccag tttggctttg ctggtccagc caaagactac cttgacatcg
    13741 caggtaaaat tctcttgaac gatcatgagg gtgaaaatct taagattgct catgtggatg
    13801 aaaagatggg tgctctttct atgaatgccg gcgtcttccg cttcgatgaa acaagtgctg
    13861 ataataccat tgccctcaac atccgctatc caaaaggaac aagtccagaa caaatcaagt
    13921 caatccttga aaacttgcca gttgtttctg ttagcctgtc tgaacacggt cacacgcctc
    13981 actatgtgcc aatggaagat ccacttgtgc aaaccttgtt gaatgtctat gaaaaacaaa
    14041 ctggccttaa aggtcatgaa caagtcatcg gtggtggaac ctttggtcgc ttgctagaac
    14101 gcggagttgc ctacggtgct atgttcccag actcgattga taccatgcac caagccaatg
    14161 aatttatcgc cttggatgat cttttccgag cagcagcaat ttatgccgaa gctatttacg
    14221 aattgatcaa ataaaacgat agaagtctga gatcttatgc ttggacttct ttttggaggg
    14281 aaagtagatg tctcaaatcg aaagaatcaa acaggctatc atggcggatt cacagaatgc
    14341 cagctataca gagcgtggca ttgagcctct ctttgcagcg ccaaaaactg ctcgcatcaa
    14401 tatcatcggt caggctccgg gacttaaaac tcaagaagca ggcctttact ggaaagataa
    14461 aagtggtgac cgcttgcggg actggctagg tgtggatgaa gatacctttt acaattcagg
    14521 ttattttgct gttttgccta tggatttcta ctttccagga catggcaagt cgggtgatct
    14581 tccgcctcgt acaggttttg cagaaaaatg gcatccgcag ctcttacagg aattgcctga
    14641 tattcagtta accctcttga ttgggcaata tgcccaagcc tactatttac aggagaaaat
    14701 cagtgggaag gtaacggaga gggtgaaaca ctataaagac tatctgccag cctattttcc
    14761 gctagttcac ccatcaccac gaaatcaaat ctggatggcc aaaaatcctt ggtttgaggc
    14821 agaagtagtg ccagatttga aaaaaagaat taaaaccatt ttatagtcaa tgaaaatcaa
    14881 agagcaaact aggaagctag tcgtaggctg ctcaaagtac agctttgagg ttgcagataa
    14941 aactgacgaa gtcggtaaca tacgcacggt aaggcgacgc tgacgtggtt tgaagagatt
    15001 ttcgaagagt attagaagaa aaagaatgaa agaaatagcc tttgacgcat tttaccagct
    15061 ttaccaaaac gaccagcttt ctctagtgga tgtgagagaa gtggatgagt ttgcagctct
    15121 tcatttagaa ggtgcccgca acctaccgct tagtcaattg gctgatagtt atgattaatt
    15181 ggacaaagat cgcttgcatt atattatttg caaatctgga atgagatcgg cgcgtgcttg
    15241 ccaattccta ttagaacaag gttataatgt tatcaatgtc cagggtggca tgttagtctt
    15301 tgaagaactt taaaattttg catttctcct acttggtgtg gactgggtag gagagtttta
    15361 tttttagata attcttattt ttaagaaaat tgaaaacatt taatatttgc ctcgtgatac
    15421 ttttttcaga ctcctaattg tggtatacta ggtcagtatt ttataaatat gaaggagatt
    15481 tttatggcta aaaaaggtac cctaacaggt ttgctcctgt ttggaatatt ttttggtgcg
    15541 gggaacttga tttttccgcc ttctctaggt gctctatctg gagaacattt tcttcctgcc
    15601 atcgcaggtt ttgtcttttc aggcgttggt atcgccgtct tgacccttat tattggaacg
    15661 ctaaatccta aaggatatat ctacgagatt tcaacgaaga tagcgccttg gtttgcgact
    15721 ctttacctct cagttcttta cttgtcaatc ggtccattct ttgctacccc acgtactgct
    15781 acaacagctt acgaagtagg gattagcccc cttttgtcgg atgcaaataa aggacttggc
    15841 ttgattgtat ttacggttct gtattttgcg gcagcctatt tgatttcgct taatccatca
    15901 aaaatcttag accgcattgg acgtatttta acgccagtct ttgcaatttt gattgttatc
    15961 ttggtcgttc tgggagctat caaatatggt ggaacaagtc ctcaagctgc ttcagctgct
    16021 tatcaagctt ctgcctttgg tacaggtttc ctagaaggtt acaatacctt ggacgccctt
    16081 gcctcagtgg cctttagcgt aatcgcagtt caaaccttga aacaacttgg attttcaagt
    16141 aagaaagaat acatttcaac tatttgggtt gttggtatcg ttgttgccct tgccttcagc
    16201 gctctttaca tcggtttagg ttttcttgga aatcatttcc cagtaccagc tgaagcgatg
    16261 aagggtggaa caccaggtgt ttacatcttg tcacaagcca ctcaagaaat ctttggctca
    16321 acagctcaac tcttccttgc agctatggtt accgtaacct gcttcacaac gactgttggt
    16381 ttaattgtgt caacagctga gttctttaat gagcgcttcc cacaaatcag ctacaaggtt
    16441 tatgcgacag cctttacctt gattggattt gctattgcca atttgggtct tgatgcgatt
    16501 atcaagtact caattccagt actggttatc ttgtacccaa tcacgattgc tatcgttatg
    16561 attgtcatgg tcaacaaatt tgttgccctt tcaaaaccag gtatgcagtt gacaattgct
    16621 gtggttacag ttattgccat tgcaagcgta ctaggaagct cgtttaaggt tgagtttctt
    16681 gcaaatcttg ttagcgttct tccttttgcc aaggcatctc tcccatggtt ggtgccagcc
    16741 attgttggaa tcttgctctc attggttcta ccaaacaagc aagaaagcga tgtttttgaa
    16801 atggaataat cacttaaatc acttttgtag ccaagtctac aggagtgatt ttcttttttt
    16861 atccgatgat aaatgtgtta taataggtag cgaaagaggt gaagaaatga atcaaacagt
    16921 aaaatatatc aaagaactga cagccatcgc atcgccaacg ggcttcactc gtgaaatttc
    16981 gaattattta gtcaagactc tagaaggttt tggttaccag ccggttcgca cagccaaggg
    17041 tggtgtcaat gtgaccatca aaggtcaaaa tgatgaagag catcgctatg tgactgccca
    17101 tgtggatacg ttaggtgcca ttgttcgtgc tgtcaaacca gatggccgtc tcaaaatgga
    17161 ccgtatcggt ggttttcctt ggaatatgat tgaaggtgaa aactgtacca ttcatgtggc
    17221 tagcacaggt caaaaggtat caggtaccat cctcatccac caaacttctt gccatgtcta
    17281 caaggatgca ggaactgcag aacgcacgca ggataatatg gaagtacgtt tggacgcaaa
    17341 agtaagcaat gaaaaagaaa ctcgtgcctt ggggattgag gtcggtgatt ttatcagctt
    17401 tgatccacga actgtcgtga cagaggcagg ttttatcaag tctcgtcatt tggacgataa
    17461 ggtcagtgca gcaattttgc ttaatctgct tcttatttat aagaaagaga aaattgaatt
    17521 gccagtaaca actcattttg ctttttcagt ttttgaagaa gtaggacatg gtgctaattc
    17581 taacattcct gctcaggtag tcgaatatct ggctgttgat atgggagcta tgggcgatgg
    17641 ccagcaaaca gatgagtaca cagtgtctat ctgtgtcaag gatgcctcag gcccttatca
    17701 ctatgacttc cgtcaacatt tggtgacctt ggcgaaagag caagatattc cttttaagct
    17761 ggacatctat ccattttatg gttcggatgc ttcagcggcc atgtccgcag gggcagaggt
    17821 caaacacgcc ctccttggcg cgggtatcga gtctagtcat tcttatgagc gtactcatat
    17881 tgactcggtg gtcgcaacag agcgtatggt tgatgcttac attaagagcg cgttggtaga
    17941 ctaatatgtg tcttatatgc cagagaattg agctcatcaa gaagggagaa aatccctatt
    18001 ttgtcaaaga gttggaaaca ggctatcttg tgattggaga tcaccagtat tttgcaggct
    18061 atagtctctt tctagccaag gaacacgtca cggaattgca ccatttagaa aaggaaacaa
    18121 gactacgttt tctcgaagaa atgagtctag tccaagaggc agttgctaag gcctttactg
    18181 ctgagaaaat gaatatcgaa ctgctaggaa atggcgatgc ccatcttcat tggcatctgt
    18241 ttcctagacg aacaggtgac atgaatggtc acggtctcaa tggacgtggt ccagtctggt
    18301 gggttccttt tgaagaaatg acagcagaaa cctgccaagc aaaatcggat gagattaaac
    18361 aattagtcaa acgtttatcg tcagaactag ataaactatt agaaataaag gagtagaaat
    18421 gaaaaaaaga taccttgtct tgacagcctt gctaaccttg agtctagcag cttgttcaca
    18481 agaaaaagca aaaaatgaag acggagaagc taagacagaa cagacagcca aaactgatgg
    18541 aacagtcgga agtaagtctc aaggaactgc ccagaagaaa gcagaagtgg ttaacaaagg
    18601 agactattac agcattcaag ggaaatacga tgaaatcatc gtagccaaca aacactatcc
    18661 attgtctaaa gactataatc caggggaaaa tccaacagcc aaggctgagt tggttaaact
    18721 catcaaagcg atgcaagagg caggtttccc aatcagtgac cattacagtg gctttagaag
    18781 ttatgaaact cagaccaagc tctaccaaga ttatgtcaat caagatggga aagaagctgc
    18841 tgaccgttat tctgctcgac ctggctatag cgaacaccaa acaggcttgg cctttgatgt
    18901 gattgggact gatggtgatt tggtgacaga agaaaaagca gcccaatggc tcttggacca
    18961 tgctgctgat tatggctttg ttgtccgtta tctcaaaggc aaggaaaagg aaacaggcta
    19021 tatggctgag gaatggcact tgcgttatgt cggaaaagaa gcaaaagaaa ttgctgagag
    19081 tggtctcagt ttggaagaat actatggctt tgaaggcgga gactacgtcg attaatactc
    19141 ttcgaaaatc tcttcagacc acgtcagcgt cgccttacct actgactgcg tcggttctat
    19201 tcacaacctc aaaacagtgt tttgagcagc ctgcggctag cttcctagtt tgctctttga
    19261 ttttcattga gtataaaaaa taaacttttc tcttgcaatt ccagataaat agtgtataat
    19321 ggatgggtat gtgaaaaaca tacttgtggg aggtaaaaat cttacattac cgccaaaacc
    19381 acaaaggagg atttagaaat ggctaaaaaa gtcgaaaaac ttgtaaaatt gcaaatccct
    19441 gctggtaaag ctacaccagc tccaccggtt ggacctgctc ttggtcaagc tggtatcaac
    19501 atcatgggat tcacaaaaga gttcaacgct cgtacagctg accaagctgg tatgatcatt
    19561 ccagttgtta tctcagttta cgaagataaa tcatttactt tcgttacgaa aacaccacca
    19621 gctgctgttc ttttgaaaaa agctgcaggt gttgaaaaag gatcaggtac acctaataaa
    19681 actaaagttg ctacagttac tcgtgcacaa gtacaagaaa ttgcagaaac taagatgcca
    19741 gatttgaacg cagcaaacgt agagtctgca atgcgtatga tcgaaggtac tgctcgttct
    19801 atgggattca ctgttgttga ctaatcaata acacagtaga aaatctcaca gcagtctatt
    19861 agttgctttt catactaggc aagtgactga gccttgtact tgggtacagc aagggagctt
    19921 aaggccgtag gaagagaaaa atagtagact gaaaacccgc aagacttcat catttcgaga
    19981 agtgacgtgg gagatgaaaa tcgattgaac cacttacaag gagaatagaa aatggctaaa
    20041 aaaagcaaac aacttcgtgc tgctcttgag aaaatcgaca gcacaaaagc atacagtgta
    20101 gaagaagctg tagcacttgc aaaagaaact aactttgcaa aatttgacgc aactgtagaa
    20161 gttgcttaca acttgaacat cgacgttaaa aaagctgacc aacaaatccg tggagcaatg
    20221 gtattgccaa acggtactgg taaaacttca cgtgttcttg ttttcgcacg tggtgcaaaa
    20281 gctgaagaag caaaagctgc tggtgcagac tttgttggtg aagatgacct tgttgctaaa
    20341 atcaacgacg gttggttgga cttcgacgta gttatcgcta cacctgatat gatggctctt
    20401 gttggacgtc ttggacgtgt ccttggacca cgtaacttga tgccaaaccc taaaactggt
    20461 actgtaacaa tggatgttgc taaagcagtt gaagagtcta aaggtggtaa aatcacttac
    20521 cgtgctgacc gtgcaggtaa cgttcaagca atcatcggta aagtatcatt tgaagctgaa
    20581 aaattggttg aaaactttaa agctttcaac gaaacaatcc aaaaagcaaa accagctaca
    20641 gctaaaggaa cttacgtaac aaacttgact atcacaacta ctcaaggtgt tggtatcaaa
    20701 gttgacgtaa actcacttta atcagtagtt aaagtaatgt aaaaaagttg aagacgctat
    20761 gtctcaactt tttttgatgt acgacgggca tgttgtatag tagattgaaa ctagaatagt
    20821 acacatctac ttctaaaaca ttgttagaaa ttgatttgac tgtcctgatc gattcgtcct
    20881 attcttattt cattttatta tatatttgag gtgtaagtcc tcggtgggca cctgctaccg
    20941 gtgaacccaa tagcgattcc caagtctgac tatcgtgagg tagcggatta aaacggtctg
    21001 gggatagacc gttttaagtc tgacgctgga aataagaatc gtcagaggaa gggatagcga
    21061 aatcgtggct ctacgaacag gaacgtgata ataaggccta tatagcggat aaggtatctg
    21121 gctggggcga ccactatcaa ttagtagctc agaagtcggt acttaaacgt gctatatcaa
    21181 aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt gaatgacatg
    21241 cgttaacagt tagttgaacc gccgtatgcc gaacggcacg tacggtggtg tgagaggggc
    21301 tagagattat cccctactcg atttcgaaat ctagtggaat gaatctggaa tagtccatcg
    21361 agctttctaa tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt
    21421 atggttactg act
//
LOCUS       DAVMCN010000030        20676 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVMCN010000030 DAVMCN010000000
VERSION     DAVMCN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.030"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(95..1726)
                     /gene="rlmD"
                     /locus_tag="VYP85_001298"
     CDS             complement(95..1726)
                     /gene="rlmD"
                     /locus_tag="VYP85_001298"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1881815.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(1800..2774)
                     /locus_tag="VYP85_001299"
     CDS             complement(1800..2774)
                     /locus_tag="VYP85_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1881816.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(2848..3462)
                     /gene="pmp23"
                     /locus_tag="VYP85_001300"
     CDS             complement(2848..3462)
                     /gene="pmp23"
                     /locus_tag="VYP85_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1881817.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3462..4436)
                     /locus_tag="VYP85_001301"
     CDS             complement(3462..4436)
                     /locus_tag="VYP85_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1881818.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4444..5700)
                     /locus_tag="VYP85_001302"
     CDS             complement(4444..5700)
                     /locus_tag="VYP85_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1881819.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(5762..6193)
                     /locus_tag="VYP85_001303"
     CDS             complement(5762..6193)
                     /locus_tag="VYP85_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881820.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6195..6794)
                     /locus_tag="VYP85_001304"
     CDS             complement(6195..6794)
                     /locus_tag="VYP85_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1881821.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(6781..7620)
                     /gene="prmC"
                     /locus_tag="VYP85_001305"
     CDS             complement(6781..7620)
                     /gene="prmC"
                     /locus_tag="VYP85_001305"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1881822.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7620..8699)
                     /gene="prfA"
                     /locus_tag="VYP85_001306"
     CDS             complement(7620..8699)
                     /gene="prfA"
                     /locus_tag="VYP85_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1881823.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(8709..9188)
                     /locus_tag="VYP85_001307"
     CDS             complement(8709..9188)
                     /locus_tag="VYP85_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881824.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(9178..9777)
                     /locus_tag="VYP85_001308"
     CDS             complement(9178..9777)
                     /locus_tag="VYP85_001308"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1881825.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALTIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            9900..10082
                     /locus_tag="VYP85_001309"
     CDS             9900..10082
                     /locus_tag="VYP85_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1881826.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10219..11592
                     /gene="mnmE"
                     /locus_tag="VYP85_001310"
     CDS             10219..11592
                     /gene="mnmE"
                     /locus_tag="VYP85_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1881827.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEEVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11639..12574)
                     /gene="dapA"
                     /locus_tag="VYP85_001311"
     CDS             complement(11639..12574)
                     /gene="dapA"
                     /locus_tag="VYP85_001311"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1881828.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12630..13706)
                     /locus_tag="VYP85_001312"
     CDS             complement(12630..13706)
                     /locus_tag="VYP85_001312"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1881829.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14292..14364)
                     /locus_tag="VYP85_001313"
     tRNA            complement(14292..14364)
                     /locus_tag="VYP85_001313"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14329..14331),aa:Thr,seq:ggt)
     gene            complement(14464..14973)
                     /locus_tag="VYP85_001314"
     CDS             complement(14464..14973)
                     /locus_tag="VYP85_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1881830.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14971..15067)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15096..15527
                     /locus_tag="VYP85_001315"
     CDS             15096..15527
                     /locus_tag="VYP85_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1881831.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15609..15986
                     /gene="mscL"
                     /locus_tag="VYP85_001316"
     CDS             15609..15986
                     /gene="mscL"
                     /locus_tag="VYP85_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1881832.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKTTELEVLQEIKALLEKK"
     gene            complement(16028..17122)
                     /gene="hemH"
                     /locus_tag="VYP85_001317"
     CDS             complement(16028..17122)
                     /gene="hemH"
                     /locus_tag="VYP85_001317"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1881833.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVSISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRGNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17277..18500
                     /gene="pepT"
                     /locus_tag="VYP85_001318"
     CDS             17277..18500
                     /gene="pepT"
                     /locus_tag="VYP85_001318"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1881834.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTTIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18536..19165)
                     /locus_tag="VYP85_001319"
     CDS             complement(18536..19165)
                     /locus_tag="VYP85_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881835.1"
                     /translation="MNNANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            19130..19351
                     /locus_tag="VYP85_001320"
     CDS             19130..19351
                     /locus_tag="VYP85_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881836.1"
                     /translation="MDLFQELICIVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHRFNIL"
     gene            complement(19622..20634)
                     /locus_tag="VYP85_001321"
                     /pseudo
     CDS             complement(19622..20634)
                     /locus_tag="VYP85_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5976 a         4337 c         3884 g         6479 t
ORIGIN      
        1 taattgatac cttgcaagaa aggaataata gctgttccta taccaagtag gaatgtaata
       61 aatgcagaaa gtcatatact gtcattcttt tctattaaat cattttgaag tgtctcaaag
      121 catccatgat ggcttcttct ttttcaggtg tacactgtgg aataatttgt ttatcctttt
      181 tagacttgtt gtaatgttct cgtaattcta ttccacattt cttttttatc tgtgcaatat
      241 ataatgtcga aacttttaat tcaaatttat tccaaacata ttctttgatt tgagcatatg
      301 ttgctttgct ctccgcactt gtcaaattca tctcatccag ctcaatttca acacttatgt
      361 gcttatcgac atcgagtttg gacaaaagtg ctaccgtctc gacgtgatgc gtttgaggaa
      421 atagatccac cggctggact ttcttcaatt catatcccaa ttcttggtag agtttgatat
      481 cacgcgccat ggttgcgaca ttgcaggaga tataggcgat gcgatcggct cctgtttggg
      541 cgcttgcttt gataaagctt tctgtcaagc ccttgcgtgg aggatcaacc aagataacgg
      601 ttggttgaat cccatcttta agccaattct tcatagcatt ttcagctgtg tcacagacat
      661 aatgggcgtt tgaaatattg ttcagctgag catttttttt actattctca accgcttctg
      721 gaatcagttc aacaccgtag acttctttga catgcttggc gactgataaa ccaatggttc
      781 caataccaga ataagcatca ataaccacgt catctttttt taactctgca aagtcaatgg
      841 ctgtttgata gagtttctcc gccatttcag tattgacttg gtaaaaggct gggccagcga
      901 tttggaagtc atttcccaac atctggtccg taatatagtc ttgaccataa agagtgcgcc
      961 actccttacc aaaaatcgca ttggtattct ggtcgttgat attttgcatg acagacacaa
     1021 tctctgggaa ctgcttgata acttgttcaa tcaattggtc aacacgaaaa acttttggac
     1081 gagttgtcac caaaacgacc atgatttgtc ctgaatagtg accacgacgc accacaagat
     1141 tccgaatcaa tccagactgt tccttttcgt cataaggttt taaatcaaaa cgacggagca
     1201 ggtctcgaag agctactacg acttggtcaa tgacaggatc ctggataaag aaatcttcaa
     1261 ggggcatgag gttgtgcgaa ttcttacgga aaaatcctgt ttccaagaca ccattcactc
     1321 gacgaacggg cacctgcgcc ttattgcgat acttgactgg atgttccata ccaagcgttt
     1381 cagcaacttc tacatctgca attccagcaa tcttgtagag actgtccttg acttgcttgg
     1441 ttttaaactt gagctgttct ggataagaaa ggtgtcctaa atccgcgatt cctgaacgca
     1501 ggtaagccaa atctagatct tgattacggt gtggtgactg gacaaggtat ttttcaactt
     1561 ttccaaagcc aatcttttta ttgaccttga ggacacgcat gagaattttt tcactcggta
     1621 aagcattctc tacaaaaaag accaaaccat ctaccttggc aactcctgcc ccttcatggg
     1681 tcaaatcaac aatttcaact tctacaatat catttttctt taacattctt ttctctttct
     1741 attggccgac aaaaaagacg gcaacgttac ggttaccatc cattatacca tgaaatttct
     1801 taagaaccaa aactcttgaa gaagttgaca agggcttgcc agagggagct taagaagtta
     1861 ccaccgtcct ctagcgcctt atccgcatca aagttaaggt tgatattttt aaaactgtcg
     1921 ccagcttgtg atacgatgct ttgtttaagg tcatttaggg ttttagtgaa atctgcattg
     1981 ctgaggatat cactctttga gagattcaag gcaaaattga tgatgatatt gatctggttt
     2041 cctgttatga cctgatcaag tttgtaattt tttaaggtat cttcaacaat cttgcggata
     2101 tcttcttctg tcagatttcc cttgctttct ttagctttgg cgagtcctga cttgatatca
     2161 gctagggcaa cgtttaattt attagcatca tagcctgatt tgtccttgtt ttcagcattg
     2221 atatctgaca aagcctttag ctcttcttga gccaaatctt tattggcttg cggcaccttg
     2281 gctccattag cttctagcga atagtagatc ccagccaaag cactctcacc tgtaactgga
     2341 atgggtgctg ctacagtgat tttggcgtgt tccacaccca aagttacggc tgcatttcgg
     2401 tacatatcct gagttacctt agtgatgttt tcaggtgttt caatcttgac ctcaagtggc
     2461 gatttgtcac ctagcttttg aatcttggct gatgaataca actgtaagct agagtcattg
     2521 gccacattca tgattttaga ataaacatca ggtgtcatgg tcttaagttc tttggtatct
     2581 gttgaggcat tgtagcccag ttttttaaga gtttgatttt tttggtcttc agatagggaa
     2641 gaacctagga catattcagg ttggacatag gtttcatcga taactttttg aacatctgtt
     2701 gctgcataga cgctattcat agctgttact gcccacaaga tcgcagcgct agtcagaaag
     2761 agtttctttc tcatagggaa tttcctcctt tacttcttta gagtaatata tctatcttaa
     2821 agaaaactta taacaaaaac acctggtcta gccagatgtt gaaaagagag tgaaacattt
     2881 gatgatgtaa aggttaagtc gtacctgtct agaataataa tagtttcctc catttacata
     2941 gagttcagca ccgtgaaaaa tggaaatggg atgaatataa ctataagtct ttccagtcgt
     3001 attaccaagc aagggggcaa cagtctcacg agagtactgt ttggctagag ccaaggtatt
     3061 ttccttgcca ttttgggcga taaaatcgat ataggcaggt ccaaaattat aggcttgaac
     3121 agctgtccag atatctacac ccttcttctg cgccagatag agattgcctg tcagagtttg
     3181 aatgccttgc cgaatgctag aggcattatc attgatggtg ttggtggaac cacttgcaga
     3241 ctcactagac tgcataacat cgccttcttt tccttttgtt tcagtataaa tcatagcaag
     3301 cacaagctct tcgtttgctg gggtgtcttt ttcactcaat atttctcgca ccatgggttg
     3361 ataggtcatg acttgtttga catcttgatg aacgcggtaa gctttatagc cagcaaaaag
     3421 gaagactgct agtacaagca ctcttcgaat tcgtttaaac attatttact ttggatatcc
     3481 tcgatatttt tgattaagat agagtaggtt ccattttcgt tttggataaa ctcaacagac
     3541 tcggcgtctt gatagacgtt attgggaacg atgagctcaa ttccatttga taaggagagt
     3601 ttttggtttt caaatttctt taattggcga ctggcatcaa tttcatcaaa ttgaacaggt
     3661 tctggtacgg cttctttgac ttggtcaata aagctcaaac gagccgtcag attgttgtca
     3721 aaaaggtcat tagccaattt ctcaggtgac aattcattgc tttcttctag gttgttgaaa
     3781 atcgctgatt tgaccttgga ttgaaattga aaatcatctg tgttaaaaga ttcagcaatt
     3841 ctctgggctg ttttttccag ttccttgata gattttttag gagaaatctt aggagcgaca
     3901 gcaagaagat tatctgaaaa atagttcaaa aaagtcccgt tgtacttgat tcgtttttca
     3961 atcaggtgat acttgcgact ctgaagattg accaccaagg cctcgtcagc acccgttcca
     4021 aatccaggca ggttattctg agtcagcttg attggattat caacttctcc tccgaggtgg
     4081 gtcaaggtct cccgcagggc aattcgcaag aaagcgaaat gttctacacc ttctttagaa
     4141 aattgaacaa aaatcaagtc attggtcttg agattttcag aaatgctaaa ctcctctttc
     4201 cagagattag ccagcgttac tgatgtctcc aacaaatcgt ctgtaatatg attgaagaag
     4261 ggattttctt cttcgaaaat cccagtcttg gcttcatctg aatacacatg ttcaattttt
     4321 ttacgtaggt attcttcgat ttttggagta atattgagaa acttatctgc taagaacagc
     4381 tcggtatcat ccggactgaa ctggtgaata atggctttct taatataaat atccataaaa
     4441 gttttagtcc tcgtataatg ggaaggcatc tgtcaattct ttgactgcac ttctcacttc
     4501 ttctaataca gcctcatttt ctgaattctt aagggtttta atgatgagtt cagccacttt
     4561 gcgactttct tcttcaccaa atccacgtgc agtaatagct gctgctccga tacgaatccc
     4621 acttgtcttg aatggcgaca aggtttcgta agggattgaa tttttattta gggtaatatt
     4681 gacttcatcc agcaagtttt gagcaacttt tccgttttct acaaccttag tcacatcaac
     4741 aaggaagaga tggttttcag ttccacctga aataatacgg aaatcagggt cttgcaagaa
     4801 gacatctgcc atagccttgc tgttcttaat tacattggca gcatattcct tgaaggctgg
     4861 atccaaaact tctttgaaag aaactgcttt agccgccaca acatgctcta aaggaccgcc
     4921 ctgaatacct gggaaaatag ctgaattgat ttttttagca agttcttcgt cattggtcaa
     4981 aatcaaacca ccacgaggtc cacgaagggt tttgtgggtc gttgttgttg tgatatgagc
     5041 gtatggaact gggcttggat gaaggccagc cgcaaccaaa ccagcgatat gggccatgtc
     5101 caccatgagc ttcgcaccga cagcatctgc gatttcacgg aattttgaaa aatcgataat
     5161 ttgagaatat gctgaagcac cagctacaat cagttttggt tttacttctt gggcttgttt
     5221 caagatagca tcaaagtcta agagttccgt ttcaggatca acactataag aaacaaagtt
     5281 gtaggtttga ccagagaagc taacaggagc cccatgagtc aaatgaccac ctgatgccaa
     5341 atccattccc ataaccgtat cacctggctc aatcaaggac atgtaagccg cacagttagc
     5401 ttggcttcct gaatgtggtt ggacattggc aaatttagca ccgaaaattt cttttgcgcg
     5461 ttcaatagca agagtctcta caacgtctac tacatcagtt ccaccataat aacggcgtcc
     5521 tgggtaaccc tcggcatatt tatttgtcaa gatagaccct tgagctgcca taacagcctt
     5581 ggaaactacg ttttccgaag caattaactc gatattattt tgttggcgtt cttcttcttt
     5641 ggcaatagca ttccagagat cagcatcata tgctttaaaa tcatctttgt caaaaatcat
     5701 aggtcttctc ctttattgtg tgactagtcc attagtttga ttttacaata agaaaatcaa
     5761 actaaaagat gcgaataaac cgtttctgca ttttatcaca agtatagcca actttttcat
     5821 aaaatgcatg agcacccaga cgatgattgg cagaatttaa gcggataaac ccataaccac
     5881 atcttttggc ttcttgttcc aacccttgta gtaaactttt accgatacct tgaccttgcg
     5941 cttgaggtga aactgctaaa gctaagatat taaatcctgc tttggaatag agtgattcgt
     6001 aaacttcagc gtggacatat ccaagtaaga catgattagc tgcatcctca tagccaagta
     6061 ggaaatgatg ggaatcctga gacagtctag ctagttggct agccgtttcc tctggactaa
     6121 aagtataacc caaagcctct tggttgatgt cacatatcgc tttcacatct gtttcttgca
     6181 aatctcttag catttcaagc ctcctcaaaa gaaatctctg gcaaccgagc aagaatatct
     6241 tctcgtttaa ttgcgccttg gcgtaagatt ttcaccttgt ctccagacaa atccacaata
     6301 gttgaatcct gtccagttag aaaagcatcg tcttccagac ccagaacctc ttggtcaaaa
     6361 tccttcagaa tttgttcaaa ggttacacca cttgcctgac ctgagatatt ggcagacggc
     6421 ccaatcaagg gacctgtctc tcgaattaaa tccagtgtga tagggtgact gggcatccga
     6481 aatccaatag ttgcaaggtc agaatttacc caatagggaa ctcggtcatt ggcttcgaga
     6541 ataatggtca agggacctgg caaaaaggtc tctacaagtt tttgtagata agctggctga
     6601 ttcttagaaa agtgcaagat atcctctaaa gaggcaacat tgagattgag cgccttgtct
     6661 ctaggacgac gtttgagctg gtaaacatgg tcaactgctt tttcgtctaa ggccttggca
     6721 aaaagaccat aaaccgtctc tgtaggcaga atgacagctc caccattttc caactcttgt
     6781 ctaatcctgt ccatcatcaa ccacgaccat cctatcttga ccaaattggt ccttgagtgt
     6841 tcgaactttt ttttcaggaa gatgttttct aaaaagttcg ggaacacttt gaccttgctt
     6901 gtatccaatt tcaaggtaaa tcttaccacc atctttgaga tagtcttttg catcttccgc
     6961 aattctacgg taaatagcta ggccatcctc gtctgcaaag agagctagat gaggctccga
     7021 atacaagaca ttcaagccta cctctgactc atcttcacga gagatatagg gtggattgga
     7081 aacaattata tcatattttt cagaaatttc tgtaaaacag tcagattttt taaaaaatat
     7141 ttgaagattt tgatttttag cattttcgct agctaaatct aaagcctctt gagaaacatc
     7201 tgctgctgtc actgaccaat ctggtctatt ttttgctaga gcgagagcaa tagctccact
     7261 acctgttcca atatccagaa ctgaaagatt cgtctcaaga ttttcagtta gaataagctc
     7321 cactaactcc tctgtttctg gacgaggaat caaaacccgt tcatccacct ttaaatgcat
     7381 tccataaaaa tctgcctgtc caatgatgta ctgagctggc ttgtgagctg ctagttgctg
     7441 gtaaatatct tctacaaatt gtttttcttc ctctgttgtc acctcctgct ggagggcaaa
     7501 aataaagtct gtaaaagata gatttttcag actacgatag acaaaagaga ggctttccgc
     7561 ttcctctcct tgtcttatca actcttcttc aaaatttgaa aataattgag ctaatttcat
     7621 tatttgttta attcttctag tttttgtgtt tggtcataaa gcaccaaggc atccacaact
     7681 tcgtccaatt taccagacaa aatcgtatct agtttttgga gggtcaagcc gatacggtgg
     7741 tctgtgacac ggttttgtgg gaagttataa gttcggatcc gttctgaacg gtcaccagta
     7801 ccgattgtcg acttacgctc agcgtcttgt tcatcctgag caatctgagc aaagtggtca
     7861 gcgacgcgtg cacggataat cttcatagcc ttctcgcggt tcttctgctg ggtacgttct
     7921 tcctgcatct caaccttgat attggttggc aagtgaacga tacgaacggc agtcgcaacc
     7981 ttattgacgt tctgtccacc agcaccagag gcgtgataga tgtcgacacg aaggtctttt
     8041 ggatcaatgt cgtattcaac ctcttcaact tctggcataa caagaactgt cgctgtcgaa
     8101 gtatgaacac ggccttggct ttctgtcaca ggaacacgtt gcacacggtg ggcacctgat
     8161 tcatacttaa gcttagagta tacagactga cctgaaacca tagcaaccac ttctttaaaa
     8221 ccaccgacac cattcataga ggcttccatg acttcaaagc gccaaccttg ggcttccgca
     8281 tacttttggt acatagttag caaatctcca gcgaaaagtg ccgcttcgtc tccaccagct
     8341 gctccacgga tttcaaggat gatattcttg tcatcgtttg gatcctttgg aaggagcaaa
     8401 attttcagtt tttcttcata ttcttctttt tcagccttgg catctttgag ttcttgcttg
     8461 gccatttctt ccaagtccgc atctccgcct gattccttaa tcatctcttc ggcatcgacg
     8521 atattttgaa ggacttgttt atactcacgg taggctatta cggtgtcacg attggaagct
     8581 tcttcttttg aaagctccat aaaacgcttg gtgtctgaaa cgacatcagg gtcactcagc
     8641 aattctccta gttcttcata acggtcttct acagcttgta gttgatcata gatgttcatt
     8701 ttttctcctt atttctcaat tgttaaatca tagattgcta ctacttcatt ctcggatatt
     8761 tccccagttt ctttaaatcc ataactgaga taacaaaatc ttgcctgttc attttctggt
     8821 tcataagaca accaaagttt attgcttaaa cctgctggcg ctgttcgaac atagtctagt
     8881 actttatcca taattggttt aaaatatcct tgattttgaa aattcttatc aatcataaaa
     8941 cgaaatagta aataatttcc actactaatt acgatctttt tatcataagc tatcatcaca
     9001 aaacctataa ttacatcatt atcataaact gccaatggag ctacaaaatc tccattttta
     9061 gtgtagacgt atgcttcagc taaactaatt gcgttggttg caatgaattg tttttgatat
     9121 tccttgacat ccaaatttaa aacatcaaaa taattttcca ttgtaacatc tcttagttca
     9181 attgtcatag ttttgctcct tgttagaggt tatcattggc gcaaaataat gtttacggca
     9241 aaccgaaata taggtttcat taccaccaat ctggatctgt tctccatcgt aaacgggcag
     9301 tccatcctgt gttcgcaaca ccatggtcgc ctttttcttg caatactgac agatggtctt
     9361 gatttcgtca atcttgtctg ctaaaagcaa gagatatttg gaaccttcga acaattcatt
     9421 gcgaaagtca tttttcaagc caaaagccat gacgggtatg tctaactcgt ccacaacacg
     9481 agctaggtcg taaacatggt ggcgtttgag aaactgggct tcatcgacca aaacacagta
     9541 aggtttttct ggtaggtctc ggatatagcc aaagatatcc gttgtttcct caatcgtaag
     9601 ggcagggcgt ttcatgccaa ttcgactcga cacatagcca acaccgtcac gcgtatccag
     9661 agccgaagtc ataatgacaa caccttttcc ttgctcctcg tagttatagg ccactttgag
     9721 aatctcaatc gttttaccag agttcatggt cccataacga taatacaact gtgccatgtt
     9781 tcttgcttca cgtccatttc taaatttttg ctacattcta gtatatcata attttcttaa
     9841 gctttaaacg gcaaaatgtg gtaaaatgga agaaatcaaa actagtggag gaagctatta
     9901 tgccatttgt acgcatcgat ttatttgaag gacgcacgct cgagcaaaag aaagctcttg
     9961 ctaaggaagt aacggaagca gttgtccgca acactggagc ccctcaatct gctgtccatg
    10021 tcatcatcaa cgacatgcca gaaggaactt acttcccaca aggggaaatg cgtactaaat
    10081 aagctagctt aagcagaatt gcttaggctt tttcaatctc caagtagcat tcattgaaga
    10141 aatatcctaa atttgttaca atttgaaaag aaacttggag aatttccaag aaaatagcta
    10201 ttaattaaag gaaacattat gattacacgt gaatttgata ccatcgctgc tatctctact
    10261 ccactaggtg aaggggctat tggtattgtc cgcctgagcg gaacagacag ttttgctatt
    10321 gcgcaaaaga tttttaaagg aaaagacttg aacaaggttg ccagccacac tctcaactac
    10381 ggtcacatta ttgatcctct gactggtaaa gtcatggacg aggtcatggt aggagccatg
    10441 aaatctccaa aaaccttcac tcgtgaagat attatcgaga ttaacaccca cggtgggatt
    10501 gcggtgacca atgagattct ccagctagct atccgtgaag gagctcgatt ggctgaacct
    10561 ggtgaattta ccaaacgtgc cttcctaaac ggtcgcgtag atttgacaca ggctgaggca
    10621 gtgatggaca tcatccgtgc caagactgac aaggccatga acattgcagt taagcaatta
    10681 gacggctccc tttctgacct cattaacaat acccgtcaag aaatcctcaa tacacttgcc
    10741 caagttgagg tcaatatcga ctatcctgaa tatgatgatg ttgaggaagc tactactgct
    10801 gttgtccgtg agaagactat ggagtttgag caattgctaa ccaagctcct taggacagcc
    10861 cgtcgcggca aaatccttcg tgaaggaatt tcaacggcta tcattggacg tcccaacgtt
    10921 gggaaatcaa gccttctcaa caacctcttg cgtgaggaca aggctatcgt aacagatatc
    10981 gctgggacaa cacgagatgt catcgaagag tacgtcaaca tcaatggtgt acctctcaaa
    11041 ttgattgata cagccggtat tcgtgaaaca gatgacatag tggaacaaat cggtgttgag
    11101 cgttcgaaaa aagccctcaa ggaagccgac ttggttctac tagtgctaaa tgccagtgaa
    11161 ccactgactg cgcaagacag acaacttctt gaaattagcc aagataccaa tcgcattatt
    11221 ctacttaata aaaccgacct gccagaaacg attgaaactt cgaaactacc tgaagaggtt
    11281 atccgtattt cagtccttaa aaaccaaaac atcgacaaga ttgaagagcg aatcaacaac
    11341 ctcttctttg aaaatgctgg cttggtcgag caagatgcta cctacttgtc aaacgcccgt
    11401 cacatttccc tgattgaaaa agcagttgaa agcctacaag ccgttaatca aggtcttgag
    11461 ctggggatgc cagttgattt gcttcaagtt gacttgactc gtacttggga aatcctcgga
    11521 gaaatcactg gggatgctgc tccagatgaa cttattaccc aactctttag ccaattctgt
    11581 ttaggaaaat aagaaaaatc catgatcctt cattcggtca tggattttat tgtctttatt
    11641 agtaatctgg tcttaagacc cctgttacag ttgccttagt tgcttcgtag tcgccatcta
    11701 cgacaacctt gataatgcgt ttagcatctt cttctggtgc tggaacaaga ggtagacgag
    11761 tgggtccagc ttcaaatccc atatagttaa gaactgcctt aactggagca ggacttggat
    11821 aagagaagag agcattaacc ttaggaatga atttacgctg aattgctgcg gctttcttca
    11881 tatcgctttc tgcaatggca gtaaacatct cgtgcatttc atccccattt gtatgagagg
    11941 caacagaaat aaccccatcc gccccaaggt tcatggcatg gaaagcatct ccatcctcac
    12001 ctgtataaat caagaactct tcaggcttgt gctcaatcaa ataagccata ttagccaagc
    12061 tagtacattc tttgacaccg ataatatttg gatagtcagc caagcgaagc atggtttctg
    12121 gagtcaattc gacaactaca cgccctggaa tgttatagat aataattggt aggtcagaag
    12181 catctgcaat agccttaaag tgctgataca tcccttcttg agaaggtttg ttgtagtaag
    12241 gaacaatagc aagcccagct gcgaaaccac caaattccgc tacttctttg acaaactcaa
    12301 tagagtcacg cgtatcatta gtacctacac ccgcaatcaa aggaacgcgt ccattgacaa
    12361 ccttttgtac agccgcaaac aactccaact cctcatcgtg ggtcaaagtt ggactctcag
    12421 cagtcgttcc tgcgagaaga attccatccg tatgatgggc caataaatgc tcaatcaagg
    12481 ctggaatagc atcaaagtta atggaaccat cctcatggaa gggggtaata aaggctgtaa
    12541 tgattttaca ttcttttaaa tcttgataag acacgaaaac acctctctat ttcaaagaag
    12601 gagttcatct gaactcctaa acgatatgac tattttaatt caaatttcaa ttcggctgtt
    12661 ggacgaacca atccacgttc atgaagagtt tcagcaatct gaactgagtt ccaagcagca
    12721 cctttgagaa ggttatctga aacaacccac atgtgaattc ctttttctgc atccaagtct
    12781 ttacggatac gaccaacaaa ggtatcacgc gaaccaactg cattgatggc ttgaggatag
    12841 atttgatgag ctacatcatc ttcaagaaca gcacctggga aggctgcgat agctgctttt
    12901 acttcttcga ttggagccac ttcttttgtt tcgatataaa cagactcaga gtgagctgac
    12961 aagactggaa tacgcacaca tgttgcagat actgcaatgc tatcatcttc cataattttc
    13021 ttagtttcct tggtcatctt catctcttcg tacgtgtaat cattatcagt gaaaacatca
    13081 atttgtggaa gagcgttaaa ggcgatagga taatgtttct tgtcaccacc tgaaggcaaa
    13141 atttccgcat gcaaatcaca tggtttcaca ccatcattca agacttcacg aagttcacgt
    13201 tgtgtctcaa gaattgctcc cataccagca cctgaaacgg cttgataagt tgaaacaatg
    13261 atacggtcca agccccattt ttggcgaacc ggctcaagag ccaccatcat ttggattgtt
    13321 gaacaattag ggcaggcaat gattccgttg tgagcatcaa gtgcatgagc attgacctct
    13381 ggaacaacca aaggaacatc tggattttga cggaaataag atgtattatc tactactacc
    13441 acgccagctt ttactgcgta tggtgcatac ttagctgatg tagaaccacc tgctgaaaag
    13501 agagcaatat caactccttc aaaagctgtt tcagtcgttt cttcaatcgt aatatcttga
    13561 tctttaaatt tcaatgactt acctgctgaa cgtgcagaag caaggtaacg gattttatcg
    13621 attggaagtg ttgattcttc caacattttt atcatctgag caccgacagc acctgtcgcg
    13681 ccgactacag caactgtata tcccataaat aacctctttc ggaattttct aaaaatttct
    13741 ataatagaag tattatacta ctttttccat gaattgcaaa gctttttcat cattttttgg
    13801 aaaataaaaa tccccaatcg ctagactagg gattaagagg catcttcatg tgatgagcag
    13861 gttcacacaa ctcatcaagg tccgctcctg cgttatgacc tccttatgct caatagtagc
    13921 ccgaagacta cctatcgact catcgcatct actattctac taaagagaat gacttttgtc
    13981 aacagacgaa actctttata ctcttcgaaa atctcttcaa acttcgtcag cgtcgccttg
    14041 ccgtatgtat ggttactgac ttcgtcagtt tcatctacaa cctcaaaaac atgttttgag
    14101 ctgacttcgt cagttctatc tacaacctca aagcagtgct ttgagcaacc tgcggctagt
    14161 ttcctagttt actctttgat tttcattgag tattagtttt atttacacag gtgcataaga
    14221 aatatattgg aaaaattggg ggcagacata acaaaaaccc ttgtaaatca agggcttttc
    14281 tgtctattta atgctaattg ccgggattga accggcgacc tcatccttac catggatgcg
    14341 ctctgccaac tgagctaaat cagcttactt aagaagtata ctataatcag aaaaacttgt
    14401 caagtttcct tagaaatttt ccataggaaa aagccaggta agaactacct agcttatctt
    14461 cttctattta cttaaatcaa ttcgacgacc aattttacca ataataatcg ctccaataat
    14521 caatgaagca aattcaccga ttcctgttgt aaaccaagta aggaagaatg gtaattctgc
    14581 tacaatattt aactctgcag cgatagtaaa catggaaatt gaaaagagga ttgaaaagaa
    14641 gaaatgatct tttcgaatca atccgttaaa gaggtaatcc ttgctatatt ttgcaaaaag
    14701 ccaaacacct aaactgagga atactaaggt tgaaccacca ccaacaaaga catctagcag
    14761 tccgaagcta aagaaattag caatcataca accgatggta actccgatga tgtacttagg
    14821 attgtaaaaa gccataaagt tcatcatttc tgaaatacga aactgataag caccatagct
    14881 gatggcattt aggggcggtg tgacagtcaa aacgacgtag atagcagcga cgattgcaat
    14941 atctgcaaca tcacgaatag ttaatttttt catcttttct cctttggcgg ttatccgcgt
    15001 gtaatatgct tggtgaaaga agctaagcac caagggttga ttcattcaac cttactagta
    15061 tagcacaata gcctgcttta tgctatactt aaagcatgaa aaaacctatt caaaaatttt
    15121 ttaacaatga aatcttagcc tatctctttt ttggccttgc gacaactcta gtttcgattc
    15181 tctcacgact agtcatttat caactaagtc atcaggaact ccttgctacg gccttggcaa
    15241 atattatcgg tatcttattt gcctttatca caaatgatac gattgtattt aagcaaaaaa
    15301 agaaaaatag acttatccgt ttagtgaaat tttctcttgc tcgcctttct acttttctgt
    15361 tagacttgtt tttaactttt ctctttgtaa cccaatttcc tcacatcata gggcaattcg
    15421 taactgaaaa cattgataag ataaatgcta ttgaaacaat aattgcacaa atattcatta
    15481 ttatcatcaa ttatatcttg agcaaggtct atatttttag aaaataatgc tccatttatg
    15541 agccttttaa ttgccttcta taatgattta ggatacaatg aaacacgaaa cattgaaagg
    15601 aaaacagtat gttaaaaaat ctaaaatcgt tcttgcttcg aggaaatgtt attgaccttg
    15661 ctgtcggtgt tgtcattgcc tctgcttttg gtgctatcgt tacttcactt gtaaacgaca
    15721 ttatcactcc tcttatttta aatcccgctt tgaaagctgc taaagtcgaa cgtatcgctc
    15781 aactttcttg gcatggagtc ggctatggta actttttaag tgctattatc aattttatct
    15841 ttgtgggtac cgccctcttc tttattatca agggcattga aaaagcacag aaactgactg
    15901 gcataaagaa agaaaaaact gccgaaaaaa aaacaaccga attggaagtc cttcaagaaa
    15961 taaaagctct ccttgagaaa aaataatcga ttaaaaggat ctagcgcaaa gctaaatcct
    16021 tttttcttta ctctttgggt aacttgcctg ctttttcaag catttttttg ataagataag
    16081 gcatcttaac attctcccgc ccttttttct caatcagttt tttcacaaat tctggcattt
    16141 gtaaatcttc agattcagct aaaatgtttt tcgtctcgtc tgaaggaact aactcatcaa
    16201 aggtctcttc ttctgggaga aattccttaa actcttgatt ttcattgcct ctaactgtat
    16261 tgaccaaagc atcaatcaaa cgagaatctg tatttggcat tggtggacga tggtagttta
    16321 ccccaaattc ctggcataag tcataacatt ctacatcatt gtcaaacaag acctcaatat
    16381 gctcactgat gaaactaata gatacaaaaa tataatggtc tggatgttct gtctgttctc
    16441 tgagatactc caaaacatct ggtttaatcc atggaatacc aatatcactc tcactctgcc
    16501 aagtgttggt atattgttct gaactcaagc ccagtttttc agcgactagc ttgctatttt
    16561 cgaaaatttg gtctatataa ggatcaccaa agtccaaggc aaaaatgggc acactatggg
    16621 ctgaaaagat gactttaaag ctgtcttgct ttacttcttc ttttaaaatc ttagcaattt
    16681 catctgccca atagtttaag agcgcttctt cctgatacca gtccttaatg accaaaaatt
    16741 gaatttgttt gctttctaaa aatttttcat agcccatgac agagtagaaa gaataatggg
    16801 gctccaaaat caagcaaata cactgttcaa ttccgtctgc ttccatttga ccgatcacat
    16861 ctggaataaa gggactggaa aacttattag caaagtagac actgtattca ttccccagcc
    16921 tagcttctac caaggcaacc tcttgacggg taattttttg cagaggcgtg cctccaattc
    16981 gtacataatt atcatagaga gtctgaatct cgtggtcttg gggtctcacc ccacgacgaa
    17041 tatttgtgaa aaaatcagct acaccttcaa aggtaatctc ttctggtgaa ccgaaggtca
    17101 tcattaaaat tgcttttttc atgactgctt ccttgtgatg tttttatcaa gtttatttta
    17161 tcattaattc atcgataagt aaacgctaac atagggacat tctcaatctt ctgtcttttg
    17221 tttttctctt ctttctatga tacaatggaa aaaataaatt caaaaggagt ttttttatga
    17281 cttatccaaa tctcttggac cgcttcttaa cctacgttaa ggtcaacacg cgctctgatg
    17341 aacactctac tactactcca agtacacaga gtcaggttga cttcgcaaca aatgtcctaa
    17401 ttcctgaaat gaaacgtgtt ggactgcaaa atgtttacta tctaccgaat ggttttgcta
    17461 ttggaacctt gccagccaac gatccgtctt taacacgtaa gattggtttt atatcgcaca
    17521 tggatactgc tgattttaat gctgaaggag tcaatccaca ggtaattgaa aactacgatg
    17581 gtggtgtgat tgaactaggg aattctggtt tcaaactcga tccagctgac ttcaagagtc
    17641 ttgaaaaata tccaggacaa acgctcatca caacagatgg aacaagcttg ctaggtgctg
    17701 atgacaagtc aggaattgct gaaattatga caaccattga atatctaact gctcatcctg
    17761 aaattaagca ctgtgagatt cgtgttggtt ttggtccaga tgaagaaatc ggtgttggtg
    17821 ccaataaatt tgatgcagaa gattttgatg tggattttgc ctacactgtt gatggtggtc
    17881 cactaggtga acttcagtac gagactttct cagccgctgg tgctgaattg catttccaag
    17941 gccgtaatgt ccaccctggt actgccaaag ggcagatggt caatgccctt cagctagcaa
    18001 ttgattttca taatcaactt ccagaaaatg accgacctga gttaactgaa ggttaccaag
    18061 gtttttacca tctaatggat gtgacaggta gtgttgagga ggtgcgtgca agctacatca
    18121 ttcgtgattt tgaaaaagat gcctttgaag cgcgtaaagc atccatgcaa tctatcgctg
    18181 ataagatgaa tgaagaactt gggagcgacc gtgtcactct caacttgaca gaccagtact
    18241 acaatatgaa agaagtcatt gaaaaagata tgactccaat taccattgct aaagccgtta
    18301 tggaagatct aggtatcacg cctattatcg aaccaatccg gggtggaaca gacggctcta
    18361 agatttcctt tatgggaatc ccaactccga atatctttgc aggtggcgaa aatatgcacg
    18421 gacgttttga atacgttagc cttcagacta tggaacgtgc agttgatacc atcattggca
    18481 tcgtagctta taaaggctaa aaagacgagg tagctcagct acttcgcctt tctttttatt
    18541 ctactggttt ttcttgattt ccagtagttg tagaagattc tgttgtttca ttttctgaag
    18601 ttgattcagc aggtttagaa tctcttgtat tgcttggttt gttttcgtcg ctagcagttt
    18661 caatgttaga ttctgcagtt gcgtttggtt ggttctcagc actggtgtta tcactatttg
    18721 cttcagcatt tcttgctgga cttgtttctt cacttgcgct agcttttgac tggatttgat
    18781 gattcaaaac tagaatagct tttgtcgatt caagtaaagc tgttttgtct ttactcttag
    18841 cagaaagttg atctaataat gcatccacct tatcaaagtc cgcatcagat ccattattac
    18901 tttctaaata agagtgaagc gacatgagaa tatcgtagag tttttgatag agtacaagtg
    18961 tctgagaatc ttgctcagca ttttcctttt cttgttgaag ggcgctagcg atacgagtca
    19021 aaacatcttt tacctgactg tttacttcat ccaagtctgc atcagccttg tttgtggcag
    19081 cttttagatt ttctacttct tctgccaagg attgtctgat tccttcttca tggatttgtt
    19141 ccaagagttg atttgcattg ttcaaaagac tttctacttc ttcctttcta tctgtcgcag
    19201 attattggtt gctatctacc atgtactcct aaaacaggag agttataatc caagattaca
    19261 aggccttaca gaaataagaa atccagataa gacaatgttc gtccaagacg ctattcgctt
    19321 cgcacagcag cacagattca atatacttta attttaaagt ttaggtgtca agacctcttt
    19381 ttagtgtgcc caaaatttag agaagtaatc aatcaactaa cttttatttt tttcaaactt
    19441 tcagtaaact gacctaaagc taactcaatc tgtctttgta gatgcttctg ctatcagcta
    19501 gaagttgatc tacttttgcc aagactgcct tctcatcaaa agttccaggt tgatagttgg
    19561 attgcaggga tggaatcttg tttttcaaag ccgcttcata tcccttagtt tgaaccttga
    19621 tgtagtgatt gtggtcgcca tgaggaatca caaaaccttc tgaatcttca cttataattc
    19681 gattggcatc aaaaaccatg accatcttct tcctcatggt ggacatgtag tgacggatta
    19741 cttaatacag aactagaaga acttcctacc tcttccgtgt tagagtgtga tgggggattg
    19801 ttaagagatg acttaggaat atagtgatag tgttccccat gtcttactat ataagcatca
    19861 cctatatctc tgacaatatc attagggtta aagacatatg tggctgctaa ttcacctgcc
    19921 gacaagtcac tctcaggaat gaaatgatag tgaccaccat gtggtactat agtaggttga
    19981 aatagaatat gagcaaattg ataaggggat tttaaagtaa tttctaacaa tgatttagaa
    20041 actatgatgt gctattctaa attcaactca ctatatataa ccatcatcgg tagtataacg
    20101 tccctgtaat tttgctacag atacttctgc actagctcct ttatcgtctt taccatgttc
    20161 ttgtttttgg cgattgattt catcttttgt tcgtacattt tctgcatgag cttgatcttt
    20221 aaggtaaaca taatactttc catctacctt aataatatat cctcccttaa cctaactgac
    20281 gatatcttga tctttcggct gatagttggg ggctttcatt agtagctctt cactaaagag
    20341 cgcatcaaaa ggaactttac cattatagta gtgataatga tcgccatgag aagttacata
    20401 accttgatct gtaatcttaa taacaatttg ttttgcttga attccttctt tttgactaac
    20461 ctagtctgga gtcaaatttt cagtcttctt agtgtcttta ttactgttta catatgaaac
    20521 acgattttta tctgtattgg cctgttagct atgttggttc agagcataaa cacacagact
    20581 taaggaaagg ataacaacag atccagctgc tatatatttc tttttaaatt tcataattac
    20641 ctcatttcta taattattta tatgatgtct tcatta
//
LOCUS       DAVMCN010000031        19012 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVMCN010000031 DAVMCN010000000
VERSION     DAVMCN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.031"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..911)
                     /gene="lytB"
                     /locus_tag="VYP85_001322"
     CDS             complement(<1..911)
                     /gene="lytB"
                     /locus_tag="VYP85_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1881837.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWF"
     gene            complement(953..1891)
                     /locus_tag="VYP85_001323"
     CDS             complement(953..1891)
                     /locus_tag="VYP85_001323"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1881838.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEYAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1902..2702)
                     /locus_tag="VYP85_001324"
     CDS             complement(1902..2702)
                     /locus_tag="VYP85_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1881839.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2952..3332)
                     /locus_tag="VYP85_001325"
     CDS             complement(2952..3332)
                     /locus_tag="VYP85_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1881840.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3390..3749)
                     /gene="rplT"
                     /locus_tag="VYP85_001326"
     CDS             complement(3390..3749)
                     /gene="rplT"
                     /locus_tag="VYP85_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1881841.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3801..4001)
                     /gene="rpmI"
                     /locus_tag="VYP85_001327"
     CDS             complement(3801..4001)
                     /gene="rpmI"
                     /locus_tag="VYP85_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1881842.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(4034..4564)
                     /gene="infC"
                     /locus_tag="VYP85_001328"
     CDS             complement(4034..4564)
                     /gene="infC"
                     /locus_tag="VYP85_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1881843.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4580..4711)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4871..6052)
                     /locus_tag="VYP85_001329"
     CDS             complement(4871..6052)
                     /locus_tag="VYP85_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881844.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKDYEFVSNDPTASSELKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEAIIPTLFVIGIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYSIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     gene            complement(6056..6643)
                     /locus_tag="VYP85_001330"
     CDS             complement(6056..6643)
                     /locus_tag="VYP85_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881845.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(7042..9282)
                     /locus_tag="VYP85_001331"
     CDS             complement(7042..9282)
                     /locus_tag="VYP85_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1881846.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSAGKVLVICGVFGFWFLFQNWQQSQASQNLADSVERVRILPDTVKVNGDSL
                     SFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLPLVYDLRKNIKGLTVLSLLITGLFFLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9266..9916)
                     /locus_tag="VYP85_001332"
     CDS             complement(9266..9916)
                     /locus_tag="VYP85_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV1881847.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9984..10553)
                     /locus_tag="VYP85_001333"
     CDS             complement(9984..10553)
                     /locus_tag="VYP85_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881848.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10730..11155
                     /locus_tag="VYP85_001334"
     CDS             10730..11155
                     /locus_tag="VYP85_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV1881849.1"
                     /translation="MLIGIPKEIKNNENCVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            11156..11569
                     /locus_tag="VYP85_001335"
     CDS             11156..11569
                     /locus_tag="VYP85_001335"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV1881850.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            11515..11841
                     /locus_tag="VYP85_001336"
     CDS             11515..11841
                     /locus_tag="VYP85_001336"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881851.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(12208..12468)
                     /locus_tag="VYP85_001337"
                     /pseudo
     CDS             complement(12208..12468)
                     /locus_tag="VYP85_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12471..12971)
                     /locus_tag="VYP85_001338"
     CDS             complement(12471..12971)
                     /locus_tag="VYP85_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881852.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            13007..13186
                     /locus_tag="VYP85_001339"
     CDS             13007..13186
                     /locus_tag="VYP85_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881853.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(13164..14132)
                     /locus_tag="VYP85_001340"
     CDS             complement(13164..14132)
                     /locus_tag="VYP85_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1881854.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14218..14433)
                     /locus_tag="VYP85_001341"
     CDS             complement(14218..14433)
                     /locus_tag="VYP85_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1881855.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14442..15296)
                     /gene="cvfB"
                     /locus_tag="VYP85_001342"
     CDS             complement(14442..15296)
                     /gene="cvfB"
                     /locus_tag="VYP85_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1881856.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15356..15913)
                     /gene="frr"
                     /locus_tag="VYP85_001343"
     CDS             complement(15356..15913)
                     /gene="frr"
                     /locus_tag="VYP85_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1881857.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15922..16659)
                     /locus_tag="VYP85_001344"
     CDS             complement(15922..16659)
                     /locus_tag="VYP85_001344"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1881858.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16743..18077)
                     /gene="trmFO"
                     /locus_tag="VYP85_001345"
     CDS             complement(16743..18077)
                     /gene="trmFO"
                     /locus_tag="VYP85_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1881859.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18322..18576)
                     /locus_tag="VYP85_001346"
     CDS             complement(18322..18576)
                     /locus_tag="VYP85_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1881860.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            18571..19012
                     /locus_tag="VYP85_001347"
                     /pseudo
     CDS             18571..19012
                     /locus_tag="VYP85_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5505 a         4285 c         3521 g         5701 t
ORIGIN      
        1 taaaaccaag attccttatc ccaaatccat tcattggctg tcatgtaacc accggatttg
       61 aagtagtacc aagcttgact atgagaatcg tagacccatt ctttttcagc cattttccca
      121 tcaaatttga gataaaacca agattcctta tcccaaatcc attcattggc tgccatgtag
      181 ccaccggatt ttagataata atagtgacca ttctcgaaaa tccattcttt atcagcatag
      241 tttccatttt ctttgatgta aaaccaagat tggtattgtt tgtcaaaaag ccaaccttgc
      301 tgtactttgg caccactagc attcacataa gcttgattaa tccactgact tgtcagtaga
      361 taaccaccgg atttgaaata atagtccttc cctttaattt ggagccattc tttctctgcg
      421 tgctgtccat ctgctttgat ataaaaccaa gcatcgtatt gagaatcata gacccagtct
      481 tctattactt tggcacctgt tgcaccaaca taggaagttc ctacccaagc atttcttttc
      541 atctttccat cttggtcaag ataataaaag gctcccttgt cttctaccca ttctgatttg
      601 gccatatagc caccagattt gaggtaaaaa tagtcgtcac cttgctttag ccattcattt
      661 tcagcatagt tagcatctgc ttttatatag aaccaagatt gataatgagt atcaaaaacc
      721 cactcatttg ctgcttgact gccatcttct ttcagatact gttttccttg ccaagtacca
      781 tcactagcca ttgcaccctc tggactagct aagaaaaata gcagagctaa aaaaataaat
      841 cttactttct tcattaacct tcttcctctg ttcttattta ttttattgta ccaaaattct
      901 cctaaattca tattacaaac taataaaaaa tcaagaacag attgattgca gtttacctca
      961 gagactcttt tacttcctga cggagttctt ccagactgct aataccgtat ttatccatga
     1021 cttttggtaa attttcgatg atgtcagggc aggcataagg attggtaaag ttagctgttc
     1081 caactccgat agcagatgcc ccagccagat acatttctag ggcagcttca gccgaatcca
     1141 ctccccccat tccaatgata ggcaggtctg ttgtttgggc tacttggcgg atgagtttga
     1201 gggctactgg aaagactgct ggacctgaca ttccacctgt tccattggcc aagattggtt
     1261 ttctggtttt gaggtcaaag cgcattccaa ccagagtatt gatcatggtc aagccacttg
     1321 ctcccgcata ttctgcagct tttgcgacag taacgatatc ggtcacactc ggggttaatt
     1381 tgacataaac tggcacttct gaggcttcca cagctgcttt caccacatca taagccaaat
     1441 ctggatcttg accaatcaaa agtccatgat tacagtggtc aacattggga caagaaatat
     1501 tgagctcgat agcttttaca ttagttgcct tggaaatccc atgagaaaca gctgcatact
     1561 cttgttttga aaaaccagct acattggcaa taataggaag atttggatat tctctttcca
     1621 gccaaggtag cttttcagcc aaaacaacct ctaaaccagg attttgcaag ccaattgcat
     1681 tgagcatacc agcaggcgtc tctgccactc ttggagttgg attcccaaaa cgtggttcaa
     1741 gggttgtcgc cttgatcata atagaaccta aaaggtctaa atcatagtac ttggcatact
     1801 cttgtccaaa gccaaaacag cctgatgctg gaataatcgg atttttcaaa tccaaaccag
     1861 gtagagacac ttgtaatcga tttgtagtca taattttctc cttataatac aactgttcct
     1921 gtgcggaaaa caggaccatc ttcacagacg cgttggctga ccgtctcgct ttctggtact
     1981 tttagaacac aggcatagca agctcccatc ccacaagcca tacgagattc cagagataaa
     2041 taggctcttg ggtgatcatc aaaggtttga ttgatatact tcatcattcc tggagcccca
     2101 cacgagtaaa cagcatcaaa ctgactatct aaatcattga taacaacgga aacatttccc
     2161 ttgatgccat aagaaccatc atctgtcgtt acaaagacct gaccatactg agccaattcc
     2221 gttttcaaaa taacagcatc cttattagca aaaccgagga ctgtcactac tttcactcca
     2281 cgttcatgca attccttggc cacctcaagc aagggtggaa caccaatccc accaccaaca
     2341 aggagaacct gattctgctc atcaaggtca gacaagtcaa aaccatttcc ctgaggcccc
     2401 atcacatcaa gagtgtctcc ctgacttaag gttgaaaaaa ttgcagtccc agctccctca
     2461 atccgataaa tgaggtgaca ctgcttgttt gccttgtcaa tagacgaaat tgaaatagga
     2521 cgacgtaaga gatgggcatc gtctggtaca cgcagatgaa gaaattggcc tgctcgcatg
     2581 gcttcaacca tttctccttc taggactaat tcaaagattg ctggcgcgat ttcctcttgt
     2641 gcaaccacct tcatggtttc caaccgaatg acacccaaac gcttcttaca tgtgagattc
     2701 ataacttttc ctccttaaat tttaagggga ccagataaag aaaagacctt gctagtgcaa
     2761 ggcctcagtt aaaatcgtac aacacaagag agcacactca aaaggtctcc tctagaaaat
     2821 tgcactattc ttttatctga caccttgtga gtctctctgg actcccctta aaggttgaat
     2881 ttttattagt atactctttc agctaaaaaa agtcaagtag aaaacgaata ttctacttaa
     2941 cttgcacgaa attatttttc acgaatgact tcgaccttat atccatcagg gtctttaaca
     3001 aagtaatagt ttggtgtagt tcctggtaga ccatttggct cagtcacttc atagcctttt
     3061 gcactgtgtt cttgatgaag tgcctcaaga tcaggtgtac tgagggcgat atgggcaaac
     3121 ccatcaccaa ccacatacgg accgtgatcg tagttataag tcaactccaa ctcataatca
     3181 tcaccctcaa gacctagata gacaatcgtg aaggcatggt ctggaaaatc tctgcgacgc
     3241 aattctttaa aaccaaaagc atcttgataa aatgcgattg atttttcaag attttctact
     3301 cgtaagcaag tgtgtagcat ttttgaagcc atatctttct cctttatttt taaaaagact
     3361 ggacaatcct gttccagtct catcagttgt tatttaccaa gttttgcttt agctgcatct
     3421 gcaagagctg tgaaagctac tgcatcgtta acagccaagt cagcaagcat tttacggtta
     3481 acttcgatct cagccaattt caaaccatgc atcaattgtg agtatgaaag tccgttcata
     3541 cgagctgccg cattgatacg agtgatccac aatttgcgga agtcacgttt tttctgacga
     3601 cggtcacggt atgcatagta gtaagagttc attacttgtt cttttgcagt acggaacaag
     3661 atgtgtttag ctccatagta accttttgct aatttaagaa tacgtttacg acgtttgcgt
     3721 gatacaacgc cacctttaac acgtgccatg ttttatttcc tccaaatatt tcctagaatt
     3781 gtttacttac agtcaagcta ttatttcaag cgagtaagca ttgctttgat acgtttgtaa
     3841 tctcctgaat gcaccataga tgctttacga agatgacgac gttgtttctt agtttttccg
     3901 tggaaacggt gagaagtgta agcacggaaa cgtttaagtc caccagaacc tgtacgtttg
     3961 aaacgtttag ctgatgcgcg gtgtgttttt tgttttggca tgattttttc tcctttattt
     4021 aactttctga caattatttt ttgtcagtcg ctggcgccaa ttgcatgaac atttgacgtc
     4081 catccatttt agcacgttgt tcgatgatgg caatatcttg agttgcttca gcaaactcgg
     4141 ctaaaacttt tgcaccaatc tctttatggg taatcatacg acccttaaag cgaatagata
     4201 ccttaacttt atttcctttt tcaaggaact tacgtgcatt acgaagtttt gtatcaaagt
     4261 cacccttgtc aattgttgga cttagacgaa cttctttcac agtaacaacg ctttgttttt
     4321 tacgttgttc tttttgcttc ttctggtact caaatttgaa cttaccgtag tccataattt
     4381 ttgcaacagg cggtttggct tggggttgaa tcaatactag gtcaacatta gcgttatcag
     4441 ccaaagcttg cgcttcactg agtggcttga tgcctagctg ttctccctca agaccaatca
     4501 agcgaacttc acgtacacga atctcatcat tgatgaataa gtcttgcttt gctatggttt
     4561 tcacctcttt tgttttatta gagaaaaaca atagcggact cgtaaatata caagcccgca
     4621 cgttatgata gcgtttcttc gaaacttttc atccgtaggg ccaggcaact taatgtcaca
     4681 aggcgagaag ctctcacttc tgcttttctc aacttttata tgataccaag ttttctagct
     4741 cttgtcaaga taaaaagtta ttttttgaaa agtttgtgtt tgtattttgg tttggttttc
     4801 gaatcaaaaa gagagaacca agttgattct ctccctatgt tagtttttct ttagcttccc
     4861 tataggaaaa ctaaacttta aaaacttcct ttttacgtga acttccccag ctttcgataa
     4921 atagaatccc cactaacaaa aggataatca ggcaaggaag taagaccatc cccatgctcc
     4981 aatttagatc gacattatca atctgcttag ataatcttcc agataaaatc tccactgaac
     5041 gcaagtaagt aaagggaatc agatgtgcaa tcctttgaag aggctgaatt gtttggatgc
     5101 caaacaataa gccaacaatc ccaatgagtg aaagaaagag gacaggcatt ttttgcttga
     5161 aaaaataagc aatcaagtac acaacttcca caatgacgat aaaggctaag aaagctaaga
     5221 gtaagccagg aaataataca tcttgtattt tcccaatagt tacttcttga ttcactaagc
     5281 tataaattga gtagggataa tctaactgtc caaaaccact tatcagactt cccactagaa
     5341 aagaaaagcc acagattccg ataaacagca cagttacata tcccactcca actccaagag
     5401 aggatattgc aaatgtcact tttgaaacag gatataagtg agctgtgtcc agatgatttt
     5461 gatatctttc tgcaaatagt tgtgttagca taaaaataat accaatcaca aataaggttg
     5521 ggatgatagc ctctaaaatc cagacaatct gatcaatccc gtgggtcgga aactccaaag
     5581 tatgtgcttt tatgttcaag ggatacaggg cttgataaat cttccgttcg cggtcaaccc
     5641 ccatttttaa ttcagagcta gcagtcgggt catttgatac aaattcataa tctttctctt
     5701 catcttgcca ctgcagatag taggcctctt tccagcgccc ttcttttagt aaagttagaa
     5761 tttctgtctt tcgcgtcaaa agattttttt gcacgtctaa attattttta gcaaactggt
     5821 attcctccga gctggtatca gacatttggg agagtttctc ttcatattca ttgatgactc
     5881 tctcacggtc tacaagacga gtttccaact ctctctccaa gctgactgag tttgcagtct
     5941 gactattaaa ataaaaagta acaccgagta cagatacaaa taaagctaag ataatccagt
     6001 ttaagcggct tttgaaaact tttttcaata aaaatagact aacatctttc ataaactaaa
     6061 cctcttctat ctgcccctga tgaatggtta ctactctatc gcagatatca accaactctt
     6121 ccttatagtg ggaacttaaa agaaccagct gttcttgtct atcgatttgt gctaacctat
     6181 caaaaaactt ctgtcgataa tactcatcta agccatttgt aatctcatcc atgagccagc
     6241 atttggcctg actgagaaaa tacatagcaa tcaccaagcg ttgcttcatg cctaaggaat
     6301 acttgcggat gggaagactg atatagtcag ccatttccca gtaggcgatt tcatctctca
     6361 agtttaggtc tgacttccag atgtttttga taagacgaag gtagtccatc ccacttaagt
     6421 ttccatccag ccattcaata ctctcataat aaaataaaga aggaggagct gcgatatttc
     6481 cactacttat gggaattaaa ttgctaatgg cacggaacag ggtcgtcttt ccagagccat
     6541 tgatagcaag aagaccataa aacctaccct ttttaaaggt gaaatccgca tcttgcaaga
     6601 tgacttgtcg cgtttttaag gtcacatgag taagctgcaa catatctagc cctccttttt
     6661 ctcactcttt aagaattaat agcctccgct gtaatagttt atgatctcat aacgaccgta
     6721 gttccagcca gaaccaactg gatactcaga atagctgtaa taacgagacc atgacggaac
     6781 gttagtatgt ctatatccat ggaaattcat actagactta tagaagatat tccaatcata
     6841 ccgatacttt taagaacact cttagcagat acactggact gaagaagacc aatagattat
     6901 aaactaacta ataaaataac ttttgctgat ttttaatgat tttatatcct caatattgaa
     6961 tacgttttca ttataccatt tttatcatta ttatgcaaca aatttttagt ttatttcact
     7021 aatctacaac atttatcctt cctatcgaac actttcgatt ttccaactat ccaacccctt
     7081 aaaacgtata gctccttgct ggtcagttcg ataaactttg ctattgatac cttccagtcg
     7141 tgtcaatgtt tcctgatggg ggagtttcat tcgattgctc tttccaactg agataagagt
     7201 aagctctggt ttgagttttt ctagaaaggc tggacttgat gattttttat tgccatgttg
     7261 gctagctttc aaaacattta ctttcaagtc tggatagtgc ttcagcaagt ccttctctcc
     7321 tttctcctcc aaatttcccg tgaagagaaa ttgcttatcc aagaatttcc catacagaac
     7381 tagggtatca tcgtgtcctc catctcccat tttccttgga gatagaactt ctaactgact
     7441 tccaaaaatg ggcaagttct cccctactat catactacgc acctttgttt gagtcgcctg
     7501 tagttctgcc acaaattcct tctgtttcag actgtctttt gatactagaa tctcccctac
     7561 atggaaagcc ttggtcatct ctgacaaatc tccaacatgc tccttgtccg tgttagtcaa
     7621 aattagctgg tcaatcttag ctactccccg acttttgaga tagggaatca aggttcgctg
     7681 ggcattgctg gtcgtcatct tttcttgcca ttttttgatt ttcttataag attctgcctt
     7741 accacctaca tctatgagaa tggttttccc agttacatcc cgtaggaaaa tactttctcc
     7801 ttgccccaca tccagcatgg tgatttcatt ttccagtgga tgcttggtaa ggaaaaagag
     7861 acctgtaatc aataaactca atactgttaa tcctttaatg tttttcctca aatcatagac
     7921 caaaggcaaa gaaattaaca ataggattaa aagccattca ttgggttgtc caaagactag
     7981 aggcctactt gccacctgtg agaccaagcg aataatgccc tccaaccatt caaagataaa
     8041 gttcagctga atgactggat agagaaagga aaggacaaat aagatagaca agagcggtaa
     8101 gaaggtcaag tcaaatagaa aggaaaagac aaaggtcaaa aggatagacc aaggttgaaa
     8161 ttccgcaaaa tagaaggata gaatgggcaa tatgcccaag gagatgacta gactttcact
     8221 agcaacagcc ttgagcccct ccccttcttt gctggtcatg gtcaggataa aagcataagc
     8281 gcaggacaag actcctcctg ctgtcaagaa aaagtttggc atgacaataa agaggagaaa
     8341 cactgtcaag gcaaaattat ccaagccctt aaccccatgt tgagccagta gcttttgcaa
     8401 gagactgcga ataaccgatg ctgaaaatcc agttagtccc gcatagataa gggaaaaggg
     8461 ataagtcagc catttcaact tttcttgggt caagcccaat cgcaagagaa gtttcttaaa
     8521 tccattcatg aaaaaaccta cctgcatgcc agatagggca aagaggtgga taattcctag
     8581 actggaataa agctcattca tctcctcaaa gtcggtgtcc agatgtccca gcaagagtcc
     8641 tgtcatgtaa ttgcgcatag ggtctggaaa gtgcgtctta atccaaacca cagcctttcg
     8701 acgtaaactg gacaagtttt ctcctatatc ccaactgcca atcttttgaa gtgactggat
     8761 tgttttgata ttgagagtct ggtaaattcc ctgagtcttc agataggctt ggtaattaaa
     8821 gccaccaaaa tttctctgcc cttctggctc cgaaagcttc ccttctagtc ctatctcatg
     8881 caggtcggtt aaagcttgaa aggcttcttt ctcctcctcg gactggagtt tataatagac
     8941 ttgaaaaatg cgtccatcag ccttgccgcg aaaggacaga ctatcaccat tgaccttaac
     9001 agtgtcaggc agaatccgta ccctttcaac agaatccgcc agattttgac tcgcttggct
     9061 ctgttgccaa ttttgaaaca gaaaccagaa gccaaagact ccacaaatca ctaaaacttt
     9121 gcctgctgat ttccatggaa attggaaaaa gagacagact agcagaaaaa caaagcccaa
     9181 caaagcaaga taggatgctg agaaaatagc gtaataaaac caaagtaaca aaaaactcag
     9241 gtaaattagg ggaatgggga tgttcttaat ccactgtaac atagtctttt agcttttcta
     9301 tggtcttagc accaatgcca gagaccttct tgagttcatc aatcgacttg aatttcccat
     9361 ttgcctcacg atggtctata atgtcctgag ctcgttttcc tcccagtccc ttaacctgtt
     9421 taagctcttc cagactggcc ttgttgagat tgaccttctt ttccttgctt gttgaagaag
     9481 ctgtccccga accagtctgt tgactaactg cttcttctcc cttagtagga acgtaaacca
     9541 gagcctcatc actaactttc tgagctagat tgagcgactt gctgtctgct tgctctgtca
     9601 agccaccagc cttctgaaca gcatcattga ctcgactacc tacaggcaag tcataaatcc
     9661 ctggcgattt gacagcacct ttgacatcta ctgtgattag atcttgttca aggggttctt
     9721 ccttctcttc cttgttcact tccttttcgg ataccaaatc cttggaaaca gctgcaactt
     9781 cagcctgcaa attcgtttcc tttacaggtg tttgtggagc tggctttagc aggaaaaatc
     9841 cgcctacaag caagcccaga ccagtacaga tgacgatgat tttatactct ttgattttct
     9901 cgataattgc ttccatattt tctcctctct tagattattc gtaagaggaa gaaaaaacag
     9961 tcgaaaaatt tcttttcaac tgcttattta tttgcaaaat agtcttcctt ggtcaagaca
    10021 taatgaactc ttgtcacgat tcggcctttt tcatgctggt ccatacaagc atatggttct
    10081 gcatgggaaa aacgcatgcc tgatttctcc atgacctttc ctgacgcagg attgtcctta
    10141 tcgtgaaggg cagtcaactt attcatccct atcttctcaa aagctagctc aatcacagca
    10201 cgattggctt ctgtcgttaa tccttgattc caatactttt tattgataat gtagccaata
    10261 gctgccttct taagaacaga atcaatcttg tgcaagtcaa tggttccaat aaactgacca
    10321 ttgcttttta gttctattcc ccaacgtccc aagggattag ccaaatagaa ctgagcaatg
    10381 ttattcttgg tttcttccaa gctttgattg gttggaaaag tgtaacgtgt attacccttg
    10441 tccgaggcat agtcaaacat tgcttccgca tcatccaaag ttacaggtct aagcaataaa
    10501 cgctccgttt ctatagacgg atactgggca agttttacaa aaattgattc catacttttc
    10561 caaccaatca aagcttgatt ttcactagtc tagcataaaa aatttggatg acaagttttt
    10621 cttgattttt gaagcggttt catatacaat gaaaccgtca catttttgat ttatgaactg
    10681 gaatgtgaca accaaaacaa gaccgtcaat tgaaaggtag gttatctcaa tgttaatcgg
    10741 aatcccaaaa gaaattaaaa ataacgaaaa ctgtgtcgcc ctcacacctg caggtgttca
    10801 tagcttagtt agtcgtggtc atcgtgtcct tatcgaaaca aatgctggtc tcggttctgg
    10861 ctttactgat gctgactatc aaaagcaagg agctgagatt gtcgctactg ctggtgaagc
    10921 ttgggcagca gagttggttg tgaaagtaaa agaaccttta agttctgaat acggttactt
    10981 gcgcgacgat cttcttctct tcacctactt gcacatggcc gctgctccag aattagcaga
    11041 tgctatgtta gcagcaaaaa caacaggaat tgcctatgaa actgttcgtg acaatcaagg
    11101 acaactaccg ctcctcgttc ctatgagtga ggttgcaggt cgtatggctg tttaaatcgg
    11161 agctcacttc cttactaagc aagctggtgg ctctggtgtt ctacttggtg gtgtaccagg
    11221 tgttccaaaa ggaaaagtaa ctatcatcgg tggtggtgtc gtcggtacac atgctgcccg
    11281 catcgccctt ggtcttggtg ctcaagtgac tattttagat attagtgcca agcgtctctc
    11341 agttctagaa gaagtctttg gaagtcaaat tcaaactctt atgtctaatt cattcaacat
    11401 tgaagcaagt gtgagagatg ctgatgtggt gattggagcc attctcatcc ctggtgcaaa
    11461 agcaccggaa ttggtgacag atgagatggt caaacaaatg cgtccaggct ctgtatcgtt
    11521 gacgttgctg ttgaccaagg tggcgttatc gaaacagctg accgtgtgac aacgcacgat
    11581 gaacccgtct atgaaaaaca cggtgttctc cactatgccg ttgccaatat ccctggtgcg
    11641 gttgcccgca cttcaaccat cgccctaacc aatgtcactc ttccttatat cgaagctttg
    11701 gctggcaaag gattcgcaca agcaatctct gaagatgaag gcttgcgtca aggtgtgacc
    11761 acttatcaag gttacttgac tagcctacca gttgctcaag gacttaatcg tgactacact
    11821 gatatcaatg atttagtata aattttgaaa agaaaagggt gacttcgcaa gtcctaccca
    11881 ctgtgctttg tgtcatcagc tattacatcg ttggtttatt gtactgtata ctttgcaact
    11941 ggagactttc gttccagact caattgtgca taagaaactc taaattgaat aaagtcaaca
    12001 gagtttcgcc caaccacttc gtcttgtaat gacaattata taaaccaaag gaagctgagc
    12061 tctttagtcc cagcttcttt ttatatataa aattttaccc gtgcaaagac agggccttag
    12121 cagacttctt ttttacttcg ttcacccttg ctttttcttt ttaggtttgg gcgttggcag
    12181 ttggttatac atagctaaaa tcaggtctta tagaaacatc ttattatcaa gttcttccac
    12241 tcaaatcatt tctttggcac ctttgtatgg aaactcaaaa gaagattggt caatcttatc
    12301 taagactgct tgcacgggtt taactaaaaa gcgatcatca taaatgccgc caataatctt
    12361 gccgcggaag taaagaatat actcccccat catggaacgg taagtcacat catctaatcc
    12421 tgataattgt tccaaaacaa attccaaata gttcttactt gatgccattt ctaatcttct
    12481 aggctctgtt cagcgataac aaccgtatag agttcttgct taacctcgca tccaattgat
    12541 ttaaaaccct gcttttccca aaaatgctga gattgcggat ttcccttaac ataagccaaa
    12601 cgtgcctttc gaaagttctt agcaaaataa gctagtgctt ctgtcacaat atgactacca
    12661 atccctttcc tctgataggc ttgatcaacc ataaacaaac caataaaaac agtctcctca
    12721 tcaggatagg catagacaaa atccataaca gccacaaggt cagatccatt ccaaaatcca
    12781 acaaaaaact tatcagcctt agctttacct tcaggtagac aaagcatgtc ctcttttaca
    12841 gttgcaaaat ttggctctgg tggacaatgc tgaaaataca gaggattact ttcatataaa
    12901 gataaaatac ttggaatatc cttttcagtt agtatcctac aactgtaata cttagatagt
    12961 tggtcaatca tcttttcaaa ttcctacttt cttgtgccct gtgattatga cacaggaaga
    13021 tgcactgatc gtcatcagcc acataaaagt tctttccatc gtgcctaatc gttgtctcag
    13081 acctttggat aaaaccttta gcctatacaa ctggattttc ctctctcaaa agtatattct
    13141 tttgcaggcg aacttcctca aaatcagtcg tgtgcaactt cagtagaata ttcataggct
    13201 cggataatct gagcgacaac tggatggcga accacatcct tggctgaaaa atgaacaaag
    13261 tcaatctgat ggatgttctt gagtttctct tgagcatcaa tcaaaccgga cttgacatta
    13321 cgtggcaggt caatctgact gatatctcca ttgacaatca tcttagaatg aaagcctaaa
    13381 cgcgtcaaga acatcttcat ctgcatgatg gtcgtgtttt gcgcctcatc gagaatgaca
    13441 aaggcatcat ccaaggtccg gccacgcata taggcaaggg gcgcaatttc gataatttca
    13501 cgctccatga gacgagtcgt ttggtctttc ccaagaattt gatacaaggc atcgtaaaca
    13561 ggacgaaggt aaggatccac cttctcctta agatcacccg gaagaaatcc aagactctct
    13621 cccgcttcca ccgctggacg agttaggata attcgcttga cttgcccacg tttaagggca
    13681 gtcactgcca aggtcactgc aaggaaggtc ttccctgtac ctgctggccc aattccaaag
    13741 gtcacatcat gctgtttgac actgtccaca taaagctttt gccctagggt tttgacacgg
    13801 ataggtttcc cagtattatc tttgataatt tcttcttcgt aaagggcgac aaacttgtca
    13861 atttcatcat ttttgaccat gctaatcgca gtgactacat ctggcgtacc aacggtcatc
    13921 ccacgattta ccaagaccat caaagcctga ataacttgac gggcttcctc acaggcagac
    13981 tcttctccca aaacctggac aatctccgta cgagcatgaa tcacaacatc aagctcttct
    14041 tccatcaaac gaagatggcg ttcattggaa ccaaaaagat gaaacaggtc atctggatga
    14101 ctcagttgaa tgtctattga atgttccttc aaataaagaa cctctctaat ccttttattt
    14161 ctttttatta tagcagaggg atggagaaat tactagccca aacccaatga ataaatgcta
    14221 gtgttctaga tattcctgcc aaatgctgtc aaaatctcct aggttaaaag agaaactggc
    14281 atgctcctcc aaaaagcgac tgacctcatc aaaatcatct gtatgttttg gaaaagctgc
    14341 ctcttcaaaa gcgaggtctg ccaaaattgc tttgggactg ttacttttag gattgcgctc
    14401 ggtcatgagc caagtgtaaa atgattttct cataagcctc cctaaatcaa ctctgtccca
    14461 aactggtcct gcttgatttt accagccttc ataagaccac ctaaagcttt cttgaactga
    14521 cctttagaaa tgccaaaggt tgccttgatg tcgtctggag atgacttatc atttaaggtc
    14581 atgaaaccgc cattactttc caaataagtc aaaatcatct gagcatcgtt ttccaacatt
    14641 tcaaaggagc gtggtttgag ggagaggttc agagtgcggt ccacttcacg gaaaccaata
    14701 acgcgcgcat ctaatacttg ccccaaacgt ggctctgcgt aacgctcgct aggatgaata
    14761 aaaccaagca tattattttc tggtaggtaa acaaaagttc ctgacagctt gagacggtaa
    14821 acaatggctg gccagttttg gttctgcatg ttgttgtagg caggacgagc aagacgttgg
    14881 aagtcttctt gataagccaa gaggccccag atacggtctt tcttatccac ttcaagacgg
    14941 atgtagagtt ggtcgccctt cttaggccag agttccttga gctcagggag aatatcgagt
    15001 gacacaacga tttccttgtc aggaaggcct gtatccacaa agacacccaa atccttacga
    15061 acctctgtga cacgtcccca accaaattgg tcctgagtgg cagtcacttc taaggttgtc
    15121 aggcggagtt tttgcttcat atccgtgtat gcaaaacctt tgaccgtatc ccctactgta
    15181 tgttgacctt cttccttagc aagagcatag gtttgaccat ccttttgcac aaagtaaaaa
    15241 cggtcatttt catcgatgat cagtccaacg ataaaacttg caagatttgt attcatattt
    15301 ccttctttcg aataaaactc agccagcaat gccaactgag tttttctgtt tatttttaga
    15361 cttccaaaag ttctttctct ttgttagcag tcatgtcgtc gatgtgttta acagcatcgt
    15421 ctgttacttt ttgaatatct ttttcaagag tcttcaattc gtcttcagtg atttcttttg
    15481 ctttttcttg tttcttagct tcgtccatag catcgcgacg gatattgcgg acagccactt
    15541 tagcattttc gccgaccttc ttcacttctt tagcaaggtc acgacgagtt tcttctgtaa
    15601 gagctgggat aaccaagcga atcacagaac cgtcattagc cggtgtgata ccaagatcag
    15661 aagcgttcaa ggcacgttcg atgtctttca atgaagactt gtcaaatggt gttaccaaca
    15721 aaacacgcgc ttctggaatc gtaattgaag cgatttggtt aagaggagtt tcgactccat
    15781 agtattctac atgtacacgg tcaagcaagc ttgcattggc acgaccagca cggataccac
    15841 caaattcacg agcaagtgat tggtgagatt gggtcattct ctctttagct ttttcaataa
    15901 ttacgttagc catattcttt cttattcctt ttcttcgata ttatttgaaa ctgttgttcc
    15961 gatattttca ccaaatacga cacgtttgat gttgcctgat tggttcatgt tgaagacaac
    16021 caagtcaatg tcgttgtcca ttgagagggt tgaggctgtt gagtccatga tacgaagacc
    16081 tttgttgata acatcacggt gggtcaattc ttcaaactta acggctgtct tgtccttctt
    16141 aggatcggca ttgtacacac catcgacgcc atttttagcc atgaggatgg catctgcttc
    16201 gatttcagct gcacgaaggg ccgctgttgt atctgtcgag aagtatggtg aaccaattcc
    16261 agcaccaaag ataacgatac ggcctttttc aaggtgacga agggcacgtc cacggacata
    16321 aggctctgcc acttgttgca tagcaatagc tgtttgtaca cgcgtatcaa ccccaacttg
    16381 ttgcaatgaa tctgccatca caagagcatt cataacagtc ccaagcattc cagtgtaatc
    16441 tgcctgaaca cggtccatac ctgcttctgc tgcaggttct ccacgccaga gatttcctcc
    16501 accgataaca agggcaattt cgatacctaa gctatgaact tcttgaatct cttttgcgat
    16561 tgtttgaact gtttggatat caatccctac gccacgttca ccggcaaggg cttcacctga
    16621 taacttgatt aaaatacgtt tatacttggg attcgccatt ttcactctcc ttctttcatc
    16681 ctacctattt tatcacaatt tctaagattt ttatagtatc atgaacaatt ctttcaaaaa
    16741 aattagacag tcaaaaattc ctctaagtcg gcaagggcac gctctgcaat tttttcataa
    16801 cgagccttct tatcacggat acgctcgcct tccaactcct tgatgatccc aaaattgaca
    16861 ttcattggtt ggaaatgttt gctgtcggca tgggtaatgt aatgagctaa gcttccaatc
    16921 gctgtcgtct cggggaaaat aacctcgctt tcttccttga agagacgagc tgcgttaatt
    16981 cccgcaacta agcccgaagc cgccgactca acatagcctt ccacccccgt catctgacca
    17041 gcaaagaaga gatttggttg tttcttggaa cggtaagtct gctcaagaag atttggtgaa
    17101 tccatgtaag aattgcgatg catgacacca taacggacaa actccgcatt ttcaagaccc
    17161 ggaatcattt ggaagacacg cttttgttct ccccatttga ggtgggtctg gaaaccaaca
    17221 atattgtata ggctaccagc tgcattatcc tgacgaagtt gcacaaccgc ataaggtgtt
    17281 ttaaattctc catcacgagg tcctgtgtag tcgtccggat actcaagacc gactggcttc
    17341 atagggccat aaagcatagt tttaatgcca cgtttggcca taacttcgat tggcatacat
    17401 ccttcaaagt acttttcttt ttcaaaagaa ttgagcggtg cttcttccgc attgaccaag
    17461 gcttcatgga aatccataaa ctcttgcttg gtcattggag cattgagata ggctgcttct
    17521 cccttatcat aacgagattt gagatagacc ttactcatat cgatagtgtt gacatcgata
    17581 ataggcgctg ctgcatcgta gaaatagaag ccatcgccat tattaagggc atgaatcttt
    17641 tcagccaggg catcgctagt caagggacca gtcgccacaa ctgtaataac atctgttggc
    17701 aattctgtaa tttcatcacg caccacttca atcaaggggt ggttgaccac tttttcggtc
    17761 accatttgag agaaaccatc acgatccacc gcaagggctc caccggcagg aacacgtgta
    17821 gcctcagcag attccaagat aacagaaccc aagcgacgca tttcttcctt gagaagacca
    17881 actgcatttg tcaaagcatc cccacgcaaa gaattggaac aaaccaactc agcaaaattg
    17941 tctgttttat gctggggtgt agacttgaca ccacgcattt catatagttt aactggaata
    18001 ccacgctctg cgatttggta agctgcttca gaacctgcca aaccagcacc gataacattg
    18061 atataagatt gagacacgac actaatacct ctttgggagt gtgaagttaa gattcacatt
    18121 gaaaaagcca atcagactta caagctttcg agtttcttgg ctcaggctga aaaagtccac
    18181 aggacttttt cactcccaca aatctttcta ttttttcttc tactagtata acaaaaaaag
    18241 ggaagaaggc aaacttccct gtttagtcat tttcttgatg taaagagata gtgagtattc
    18301 cagttaagaa tcaattatat gctactctat aaaatctttt ccacataacg gatcgatagg
    18361 gactgttatt ctatctcttg ctataaccgt attatctaaa acagcataac attcaacata
    18421 gtgatctcct ttaaactgtg aatcttcgtg atattttatt ttacctgaaa aaatagcacc
    18481 acgctcacaa tttcttctaa tagcctcagc ttcaatattt cttactttcc aatagacttc
    18541 ctgcgaaaca aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact
    18601 gatgcacgat ttaagcgtct tgttggtgtt cagcgcacga cttttgaaga gatattagct
    18661 gtattaaaaa cagcttatca acttaaacac gcaaaaggtg gacgaaaacc taaattaagc
    18721 ctagaagacc ttcttatggc cactcttcaa tatgtgcgag aatatcgaac ttatgaacaa
    18781 attgcggctg attttggtat tcacgaaagc aacttaatcc gtcggagcca atgggttgaa
    18841 gtaactcttg ttcaaagtgg tgttacgatt tcaagaactc ctctcagttc tgaggacacg
    18901 gtaatgattg atgcgacgga agtacaaatc aatcgcccta aaaaaagaat tagcgaatca
    18961 ttctggtaaa aagaaatttc acgctatgaa ggctcaagcg attgtcacaa gt
//
LOCUS       DAVMCN010000032        18855 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVMCN010000032 DAVMCN010000000
VERSION     DAVMCN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.032"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            98..170
                     /locus_tag="VYP85_001348"
     tRNA            98..170
                     /locus_tag="VYP85_001348"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:131..133,aa:Thr,seq:tgt)
     gene            193..264
                     /locus_tag="VYP85_001349"
     tRNA            193..264
                     /locus_tag="VYP85_001349"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:225..227,aa:Gly,seq:gcc)
     gene            272..357
                     /locus_tag="VYP85_001350"
     tRNA            272..357
                     /locus_tag="VYP85_001350"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:306..308,aa:Leu,seq:taa)
     gene            367..440
                     /locus_tag="VYP85_001351"
     tRNA            367..440
                     /locus_tag="VYP85_001351"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:401..403,aa:Arg,seq:acg)
     gene            456..529
                     /locus_tag="VYP85_001352"
     tRNA            456..529
                     /locus_tag="VYP85_001352"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Pro,seq:tgg)
     gene            535..608
                     /locus_tag="VYP85_001353"
     tRNA            535..608
                     /locus_tag="VYP85_001353"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Met,seq:cat)
     gene            622..695
                     /locus_tag="VYP85_001354"
     tRNA            622..695
                     /locus_tag="VYP85_001354"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:656..658,aa:Ile,seq:cat)
     gene            706..795
                     /locus_tag="VYP85_001355"
     tRNA            706..795
                     /locus_tag="VYP85_001355"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:742..744,aa:Ser,seq:tga)
     gene            809..882
                     /locus_tag="VYP85_001356"
     tRNA            809..882
                     /locus_tag="VYP85_001356"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Met,seq:cat)
     gene            886..958
                     /locus_tag="VYP85_001357"
     tRNA            886..958
                     /locus_tag="VYP85_001357"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:919..921,aa:Phe,seq:gaa)
     gene            978..1048
                     /locus_tag="VYP85_001358"
     tRNA            978..1048
                     /locus_tag="VYP85_001358"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1010..1012,aa:Gly,seq:tcc)
     gene            1084..1157
                     /locus_tag="VYP85_001359"
     tRNA            1084..1157
                     /locus_tag="VYP85_001359"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1118..1120,aa:Ile,seq:gat)
     gene            1164..1251
                     /locus_tag="VYP85_001360"
     tRNA            1164..1251
                     /locus_tag="VYP85_001360"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1198..1200,aa:Ser,seq:gct)
     gene            complement(1377..2312)
                     /locus_tag="VYP85_001361"
     CDS             complement(1377..2312)
                     /locus_tag="VYP85_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1881861.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2309..3169)
                     /locus_tag="VYP85_001362"
     CDS             complement(2309..3169)
                     /locus_tag="VYP85_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1881862.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3277..5439
                     /locus_tag="VYP85_001363"
     CDS             3277..5439
                     /locus_tag="VYP85_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1881863.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALILCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKVTIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5531..6790
                     /locus_tag="VYP85_001364"
     CDS             5531..6790
                     /locus_tag="VYP85_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1881864.1"
                     /translation="MEWYKKIGLLATTGLALFGLSACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLGKDIVAKGQIPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMINDLNVFFNPMKADVD"
     gene            6804..7670
                     /locus_tag="VYP85_001365"
     CDS             6804..7670
                     /locus_tag="VYP85_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1881865.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGELALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7684..8517
                     /locus_tag="VYP85_001366"
     CDS             7684..8517
                     /locus_tag="VYP85_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1881866.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHILSGMSNGAV
                     K"
     gene            8518..8598
                     /locus_tag="VYP85_001367"
                     /pseudo
     CDS             8518..8598
                     /locus_tag="VYP85_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8875..10317
                     /gene="gtfA"
                     /locus_tag="VYP85_001368"
     CDS             8875..10317
                     /gene="gtfA"
                     /locus_tag="VYP85_001368"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1881867.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            10455..11648
                     /locus_tag="VYP85_001369"
     CDS             10455..11648
                     /locus_tag="VYP85_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1881868.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12334..14313
                     /locus_tag="VYP85_001370"
     CDS             12334..14313
                     /locus_tag="VYP85_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1881869.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            14380..15876
                     /locus_tag="VYP85_001371"
     CDS             14380..15876
                     /locus_tag="VYP85_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881870.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15876..16802
                     /locus_tag="VYP85_001372"
     CDS             15876..16802
                     /locus_tag="VYP85_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881871.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16811..17878
                     /locus_tag="VYP85_001373"
     CDS             16811..17878
                     /locus_tag="VYP85_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881872.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPHHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17889..18815
                     /locus_tag="VYP85_001374"
     CDS             17889..18815
                     /locus_tag="VYP85_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881873.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5452 a         3422 c         4052 g         5929 t
ORIGIN      
        1 ggtttggcgg aattggcaga cgcaccagat ttaggatctg gcgcttaacg gcgtgggggt
       61 tcaagtccct taacccgcat taagatataa caaatgagcc ggcttagctc agttggtaga
      121 gcatctgatt tgtaatcaga gggtcgcgtg ttcaagtcat gtagccggca tttttagata
      181 gaagaaaaca gtgcgaacgt agttcagtgg tagaacacca ccttgccaag gtgggggtcg
      241 cgggttcgaa tcccgtcgtt cgcttagaga ggccggggtg gcggaactgg cagacgcaca
      301 ggacttaaaa tcctgcgatt ggtaacgatc gtaccggttc gattccggtc ctcggcataa
      361 tatggagcac ccttagctca actggataga gtacctgact acgaatcagg cggttagagg
      421 ttcgactcct ctagggtgca tttttctatt taactcggga agtagctcag cttggtagag
      481 tacttggttt gggaccaagg tgtcgcaggt tcgaatcctg tcttcccgat tcatggcggt
      541 gtagctcagc tggctagagc gtccggttca tacccgggag gtcgggggtt cgatcccctt
      601 cgccgctata atgatcttgt cggaccttta gctcagctgg ttagagctct cggctcataa
      661 ccgagtggtc gtaggttcaa gtcctacaag gtccatttga atattggagg attacccaag
      721 tccggctgaa gggaacggtc ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga
      781 atcccacatc ctccttttat attattaacg cgggatggag cagctcggta gctcgtcggg
      841 ctcataaccc gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc ggtagctcag
      901 ttggtagagc aatggattga agctccatgt gtcggcggtt cgattccgtc tcgcgccatt
      961 ttattgatag tatttatgcg ggtgtagttt agtggtaaaa ctacagcctt ccaagctgtt
     1021 gtcgcgagtt cgattctcgt cacccgcttt gaactttgtt caaattacca agttttttaa
     1081 cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg tcggtggttc
     1141 gagtccactc gtgcccatta attggagaat tactcaagag gctgaagagg acggtttgct
     1201 aaatcgttag gtcgggtaac tggcgcaagg gttcgaatcc cttattctcc gttttaatga
     1261 gagtctgtaa ctctcttttt tatttttaga gccaataaaa cttcagatcc gtaaaactta
     1321 attgaattac taatctgaag ttatttttat atcgtttata ttataattgt gttattttac
     1381 ttccaactat tgagagaaat ttcgccacta tttagccaga tttcttttcc gttatcacat
     1441 tgaactaaaa gttttccatt ttctgagatg tctttagcaa gtcccttgta gtctttttgc
     1501 tctagtgtga aagtgacttc ttttcctaga atgaatgact gttttttgta taggtataat
     1561 agctcttctg ctggtgtttc gaagaaagca cgccagattt ctatgatcaa ttcattcctt
     1621 gttataggag ctgtagcttt aaataagctg gcagcttttt cttttaattc ctgagggaag
     1681 tctttaatag tgaaattgat acctactcca ataatgatat ctgtgactaa gccagtttct
     1741 acagaggtca ttgcttcagt aaggattcct ccaattttat gattgtttag atagatatca
     1801 ttgacccatt ttatgtcgac atctattaaa gttaggttct taatggcttt gtagacagct
     1861 ccagctacaa gtagtgtgta ggatggtaat ttgtcatagg ggagatttgg tttaagatgg
     1921 agtgtcatat aaataccacc ttgtggtgag tagaaggaac gttgaaaacg gcctcggcct
     1981 gctgtttgat aggaagctag atagagggta tttgcttcat ggcctaaatc aattgcttct
     2041 tttgcatcta gttgtgttga ttttgtttcg ggtttaaagc tgactttaat tggaagattt
     2101 tcttctagaa tctctggaag aataaggtca ccattcatca gtttatatcc tctatttttg
     2161 atactatcaa tttcaatgcc ttcttgttct agtcgcttga tggctttcca aattgctgtt
     2221 cggcttaggg atagtttttc tgcgattttt tctccgctga tatagtcggt ttctttagat
     2281 aggatttggt agacagcttg gtaggatttc ataatgttgc ctttcttact agttggtatt
     2341 gagagtattc ttttcttgta tgacttggag tctgattaaa gtattgttta taagctttcg
     2401 aaaaatggag tggatctgaa aaacctaccg agtatgcaat taccttgatg gactcttggg
     2461 tattttcgag aagttgtcta gctcggtgca ttcgaacgta gagtaggtat tctttgggtg
     2521 ataaggtatt aaattctttg aatacgcttg ataagtagct tctgtgaacg gatagttctt
     2581 ttgctaaatc ttgaattgta agtgattgag gatagtggct atcaattaat cgtttgcatt
     2641 caagatagag ttggtgggtt gatgaaatat tctttttttt ctgattggga gcaatagttc
     2701 ccagatgaaa catcagttca tgaagttgtc ccatgatatg gagttgagct aattcacttg
     2761 attttgtaat ctgagcgaag cggacaatgt ctgagatgag ttttgcagta gtctgggtat
     2821 gacaagtttc agattggatg agataggatt gatcagaaat ttgggaaaga gcaaaataat
     2881 caggggcttt ccctccagtg attcctaacc agtagtaggc ccaaggttct ttactatctg
     2941 cttgataaaa ggttagttcc tctggtttta atagaaagaa atctccttct tttaaatcaa
     3001 caattttacc cttgtaatga aattttcctt gtcctttagt aatgtaatgt agaacgtatg
     3061 tatcacgaat ggctggacca aaagagtaat taggtgtgca ttcctcatat ccataaaagc
     3121 ttagggcaag gtcgattgtt ccagtctggt attctgaaaa aactaacatg tgctacctcc
     3181 tacctaacat tttaccatat tcttgagaca tttttctatt ttggaaagcg atttcaggtg
     3241 ataaaatata atcaataaag tgatgaggtg aagtaaatgg gagttaggat agagaataat
     3301 ctattttatg ttgagagtaa aaatctaagt ttgattattg aaaatcgaaa tggctactta
     3361 cttttgaaac atttaggaaa gactattaag aactataaag gttccaatag tgtttatgaa
     3421 cgagaccatg ccttttcagg aaatccaacg gctactaatc gaacctttag tttagatact
     3481 cagcgacaga tttttggaca acatggctta ggagatttta ggaaaccaac catacaggtt
     3541 cagcatagtg taactgaagt aacagacttt cgatttgtag aagcaaagat tttaaaaggt
     3601 cagaatggtc cacagggctt accttctcca catagcatgg acgatacaga gactcttgtc
     3661 ttaatgttag aagattctaa ggctcaactt agtctgactt tgtattatac tacttttaat
     3721 aatgatgcga ctattgctag ctacagtaaa ttagataata atagtaatca ggaagttgtc
     3781 atccataaag atttttcttt tatggctgat tttccagctg cagattacga aatagtaact
     3841 ctgcagggtg cttatgctcg tgaaaagact gttagacgtc aacaggtaga acaaggaatc
     3901 ttttcgatta gttcaaaccg aggtgcttct ggtcatgctc aaacaccagc tcttatacta
     3961 tgcgaacaag gagtcacaga ggatgctggg aatgtgtttg ctattcaact aatgtatagt
     4021 ggcaactttg aagcttttgt tcaaaaaaat caattgaatg aagttcgggt ggctattggc
     4081 attaatccag aaaacttttc ttggaagtta gcccctgagg aatactttga aacaccggta
     4141 gctttagtga ctcattcaga tcagggatta actggtatta gtcatgaaag tcagaatttt
     4201 gtactgaagc acattatgct aagtgaattt tctaaaaaag aacgtccaat tctaatcaat
     4261 aactgggaag ctacttactt tgactttcag agagaaaaac tgttagagtt agcagatgaa
     4321 gctaagaaag ttggcattga actttttgta ttagatgatg gttggtttgg caatcgtttt
     4381 gatgataatc gtgctttagg tgattgggtt gttaatgagg aaaaactggg tggaagtcta
     4441 gaaagtctga tttcagctat ccatgaaaga ggtttgcagt ttggactttg gttagaaccc
     4501 gaaatgattt ctgtagatag tgatttgtat cgtcgacatc ctgactgggc tattcaggtt
     4561 cctgactatg agcatactta ttctcggaat caattagtac ttaatcttgc caatcctcag
     4621 gtagtagaat acttgaaaag tgtcttagat caactcctat cttatcatga tattgattac
     4681 attaaatggg atatgaaccg caatatcact aagctaggga atggattaac ttatctagag
     4741 acacagatgc aatctcatca gtacatgctg gggctttacg aactcgtttc ttatctgaca
     4801 gagaagcaca gccatattct ctttgagtcc tgctctggtg gtggtggacg aaatgatctt
     4861 ggtatgatgc gctatttccc acaagtctgg gctagtgata atactgatgc cattgcacgt
     4921 ttaccaattc aatacggttc atcctatctc tatccaacca tttctatggg ggctcatgtg
     4981 tcagcagtac cgaatcatca gatgggacga atgacaccat tagaaacacg tggccttgta
     5041 gcaatgatgg gaaatttggg ctatgaactt gatttgacaa atttatcaga tgaagagaaa
     5101 gttacgattg ctaatcaggt gaacttgtat aaagaattac gaccagtagt tcagttagga
     5161 cagcagtata gactaattaa tcctgatact gcatccaatg aagcagctgt acaatttaat
     5221 tacggaaatc aaacgattgt aacctacgtt cgcgttttat ctgttgtaga gaccatggaa
     5281 acaactttaa aattaaaaga tttggatgaa gagggactat ataaattaca ggaaaatggc
     5341 gaagtttact caggtgcaga actaatgtat gcgggcttaa ctgttatctt atcccaagga
     5401 gattttttga gtagacagta tatttttaga aaactatgat atgtactgac cccaaaagtt
     5461 agatttattc tgtctaactt ttggggtgca gatcaataag ggtgtataaa tttataaagg
     5521 aggctttcta atggaatggt ataaaaaaat cggacttctt gcaactacag gtttagcttt
     5581 gtttgggctc agcgcttgct ccaactatgg taaatctgcg gatgacacag tgaccatcga
     5641 gtatttcaac cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc gtgattttga
     5701 gaaggaaaac cctaagatca aggtcaaagt cgtcaatgta ccaaatgctg gtgaagtatt
     5761 gaagacacgc gttctcgcag gagatgtgcc tgatgtggtc aatatttacc cacagtccat
     5821 cgaactgcaa gaatgggcaa aagcaggtgt ctttgaagat ttgagcaaca aagactacct
     5881 gaaacgcgtg aaaaatggct acgctgaaaa atatgctgta aacgaaaaag tttacaacgt
     5941 tccttttaca gctaatgctt atggaattta ctacaacaaa gataaattcg aagaactggg
     6001 cttgaaggtt cctgaaacct gggatgaatt tgaacagtta ggcaaagata tcgttgctaa
     6061 aggacaaata ccatttggaa ttgcaggtgc agatgcctgg acactcaatg gttacaatca
     6121 attagccttt gcgacagcaa caggtggagg aaaagaagca aatcaatacc ttcgttattc
     6181 tcaaccaaat gccattaaat tgtcggatcc gattatgaaa gatgacatca aggtcatgga
     6241 catccttcgc atcaatggct ctaagcaaaa gaactgggaa ggtgctggct ataccgatgt
     6301 tatcggagcc ttcgcacgtg gggatgtcct catgacacca aatgggtctt gggcgatcac
     6361 agcgattaat gaacaaaaac cgaactttaa gattgggacc ttcatgattc caggaaaaga
     6421 aaaaggacaa agcttaaccg ttggtgcggg agacttggca tggtctatct cagccaccac
     6481 caaacatcca aaagaagcca atgcctttgt ggaatatatg acccgtccag aagtcatgca
     6541 aaaatactac gatgtggacg gatctccaac agcgatcgaa ggggtcaaac aagcaggaga
     6601 agattcaccg cttgctggta tgaccgaata tgcctttacg gatcgtcact tggtctggtt
     6661 gcaacaatac tggaccagtg aagcagactt ccataccttg accatgaact atgtcttgac
     6721 cggtgataaa caaggcatga tcaatgattt gaatgtcttc tttaacccga tgaaagcgga
     6781 tgtggattag gagtagagag actatgaaaa aagtattaca aaaatattgg gcatgggctt
     6841 ttgtggtcat ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg tttcaaggag
     6901 ccttttacag ttttaccaac tggacaggat tgacttataa ctacaaattt gtcggcttaa
     6961 acaactttaa gctcctcttc atggatccaa aattcatgaa tgcgattggc tttaccgcaa
     7021 tcattacgat tgccatggtg gttggtgagc ttgcactcgg gatcttcatt gcgcgtgtct
     7081 tgaattctaa aatcaaaggc caaaccttct tccgtgcttg gttcttcttc ccagctgttt
     7141 tatctggttt gacagtggct ttgatcttca agcaagtctt caactacggt cttccagcga
     7201 ttgggaatgc ccttcatatt gaatttctcc aaaccagtct tttagggact aagtggggag
     7261 caatctttgc ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc atcatcatct
     7321 tcctagctgg tttgcaatct attccaactg agattacaga ggcagcaagg attgatggtg
     7381 cgactagcaa gcaagttttc tggaacattg aattgcctta cttgctacca agtgtctcta
     7441 tagtctttat cctagcccta aaaggtgggc tgactgcctt tgaccaagtc tttgccatga
     7501 ccggtggtgg tccaaacaat gccacaacct cacttgggct cttggtttat aactatgcct
     7561 ttaaaaacaa ccaattcggt tatgccaatg ccattgccgt aatcttgttc ttcttaattg
     7621 tagtgatttc gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa gaggagaagc
     7681 atgatgaaac aagatgaaag aaaagccctg attggcaaat acattctatt gattctagga
     7741 tcggttctga ttttagtgcc gctccttgct accctcttta gttccttcaa acccactaag
     7801 gatattgtag ataatttctt tggctttcca accaacttca catgggacaa ctttagccgt
     7861 ctcttagctg atgggattgg aggctattat tggaactctg tcgtcatcac tgtcttgtct
     7921 ttacttgcag taatgatctt tatccctatg gcagcctact ccatcgctcg caatatgagt
     7981 aaaagaaaag cctttaccat catgtatacc ctcttaatcc tcggaatctt cgtacctttc
     8041 caagtcatca tgattccgat tacggttatg atgagtaaac tcggtttggc taataccttt
     8101 ggtttgatct tgctctactt gacctatgcg attccacaga ccctctttct ctatgttggc
     8161 tatatcaaaa tctcgattcc agaaagtctg gatgaagcag cagagatcga tggggctaat
     8221 caatttacaa cctatttccg catcatcttc ccaatgatga aaccgatgca tgcgacaacc
     8281 atgatcatca atgccctttg gttctggaat gacttcatgt tgccactcct tgtcttgaac
     8341 cgggattcca aaatgtggac tctgcctttg ttccaataca actacgcagg ccaatatttc
     8401 aacgactacg gaccaagctt tgcctcttac gtggtcggca ttatcagtat caccattgtc
     8461 tatctcttct tccaacgcca tatcctttca ggaatgagca acggggcagt gaagtaatac
     8521 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa acactgtttt
     8581 gaggttgtgg atgaaactga cgaagtcagt aaccatacct acggtaaggc aacgctgacg
     8641 tggtttgaag agattttcga atagtataag aagagctcat ggaatctata gtctttgaca
     8701 cagaggaaga gttcagcttg ttgataattc tatgtagaaa acaagaaagt agtactttgt
     8761 ttatcacagt ctatattagt acgagtttga tgataaatag agatttaaaa tgaattttat
     8821 ttatgaagcc agatcatatg agacttggct tcaattagaa aaaggagagt aatgatgcca
     8881 attcaaaata aaaccatgtt gattacctat tctgatagcc ttggaaataa tcttaaagac
     8941 ttatatgata atttggaaga gcattttgga gatgctattg gaggagttca ccttttacca
     9001 tttttcccat caacaggtga tcgtggattt gcgccagttg actacgacga agtggactca
     9061 gcttttggtg attgggagga tgttaagcgt ttaggtgaga gatattatct tatgtttgat
     9121 tttatgatta atcatatttc tcgtcaatcc aagtattata aggactatca agaaaaacat
     9181 gaagccagtg aatttaaaga tctcttttta aactgggata agttttggcc agaaaaccgt
     9241 ccgacacagt ctgatgtaga tttaatttac aagcgtaagg atcgtgcacc aaagcaagag
     9301 attgtgtttg aagatggttc agtggaacat ttgtggaata cctttggtga ggagcagatt
     9361 gatcttgatg tgaccaaaga agtaactatg gaatttatcc gtaagaccat tcagcacttg
     9421 gcaagtaatg ggtgtgattt gattcgtcta gatgcctttg cttatgcagt gaagaaattg
     9481 gatactaatg atttctttgt ggaaccagat atttgggatt tattggacaa agttcgagat
     9541 atcgctgctg agtatgggac agagctttta cctgagattc atgaacacta ttcgattcag
     9601 tttaaaatag cagaccatga ttactatgtt tatgattttg ctcttccaat ggtgacactt
     9661 tatactcttt acagttccag aacagagcgt ttggctaagt ggttaaagat gagcccgatg
     9721 aagcaattta cgacgctaga tacccatgat gggattggag tagtagatgt caaggatatc
     9781 ctgaccgatg aggagattga ctatgcttca aatgaacttt ataaggttgg agccaatgtc
     9841 aaacgtaagt actctagtgc cgagtataac aacttagata tctaccaaat caattcaacc
     9901 tactattcag cgcttggaga tgatgatgtc aagtattttc tcgctcgtct aattcaagct
     9961 tttgccccag gtattcctca ggtttactat gtgggtctat tagcaggcaa gaatgacttg
    10021 aaattattag aagaaactaa agaaggtcga aatattaatc gtcattacta tagcaacgag
    10081 gaaatagcaa aagaagtgca acgacctgtt gtgaaggccc ttctcaatct attttctttc
    10141 cgtaaccgtt cagaagcctt tgatctagaa gggactactg agatagagac accaacagct
    10201 cacagcattg taatcaaacg tcaaaataaa gataagtccg taacagcagt agcagaaatt
    10261 gatttgcaaa atcagactta tcgggtaatt gagaatggag ttgaagtaac attttgaagc
    10321 cttgatatgg tggataaaat agggttttta ttttggaaaa cgtttccttt gttttcaaat
    10381 tgctaaaaaa gtggtacaat ataggatagc ttactattat ctgaatcagc tgatttggag
    10441 agaaaggatt cattttgaaa tcaataggct ttattgaaaa gctgaagggg ttgtctagta
    10501 aagagctgat tttattggga attatcctga gtatcttttt acccttttat ctttttgtag
    10561 ttgtactctg tttatatatt atcagtttga tttttacagg agacatgaaa agtattcttc
    10621 agaaaatggg ggagcatccg atgctgcttc tttttcttag ctatagtact gttatatcca
    10681 ttcttgcaca aaattggatg ggtcttgtgg cttcagtagg aatgtttcta tttactattt
    10741 tctttttgca ctatcagtcg attttatccc ataaattctt tcgattgatt ttgcagttcg
    10801 tcttgtttgg tagtgtcttg tcagctgctt ttgccagttt agaacatttc caaattgtga
    10861 agaaatttaa ctatgctttt ctttcaccca atatgcaggt gtggcatcag aaccgggcag
    10921 aagtgacctt ctttaatcct aattattatg gaattatttg ttgtttctgt attatgattg
    10981 ctttctatct gtttacaacg accaagttga attggttgaa agtattctgt gtgattgcag
    11041 gctttgttaa tctctttggt ttgaacttta ctcaaaatcg aactgccttt cctgctatta
    11101 tcgctggagc aattatctat ctctttacga ctattaaaaa ctggaaggcc ttttggctta
    11161 gtattggggt cttcgcgatt ggtttgagtt tcctcttttc tagtgatttg ggagttcgaa
    11221 tgggtacttt agactcttct atggaagaac gcatttctat ctgggatgct gggatggcct
    11281 tgtttaagca aaatcctttt tggggtgaag ggccattgac ctatatgcac tcttatcctc
    11341 ggatacatgc tccttatcat gaacatgccc acagtcttta tattgatacg attctgagtt
    11401 acggaattgt gggtaccatt ttattagttt tgtcttctgt tgctcctgtt cgcttgatga
    11461 tggatatgag tcaggagtcg gggaaacgtc cgattatcgg cctttatcta tctttcctta
    11521 cagtggttgc tgtgcacgga atttttgact tggctctctt ctggattcag tcaggcttta
    11581 ttttcttgct agttatgtgc agtattccat tggagcatcg aatgttggta tcggacatga
    11641 cggattaagt tttataagtt tgaaatcttc taccttgggt aggagatttt tttatacgat
    11701 gggcatgtcg tgcatctgag gtgtaagtcc tctgtaggga tccactaccg gtgaatacaa
    11761 tagcgctccc caagcctgac tatcgtgagg tagcggatta aaatggtctg gggatagatc
    11821 gttttaagtc tgacgcagga aataagaatt gtcagagaaa gcaatagtga aatcgtaggc
    11881 tatgaataga aacgtgatag cgaggagcat atagtggaca aggtagcgag aaattttaaa
    11941 gtataaaaga tagtcttaat ctatatgtgt aaatcacgaa agtaattgaa ttcggaataa
    12001 ggttggtgtg aaaagacata gtaaactgaa tcttgaatac tagaatgata cttctacaat
    12061 attgttataa tttaatttga attccaaaat cacattgttc cgtccgtatt tcattttact
    12121 gtatgtcttc ctaagctcca aaatttctgt gtcaaatttc ctattttcac tgtagtcttt
    12181 gacacttcga acgacaattt gaatcatata ttcaaaaaaa atgaaaaatt tgtgccaaca
    12241 agcctaaata ttctgaaaat ttgtttgatt tttaatggat aatgtgatat aatggttgtc
    12301 aatctataat tcacataaac agaggagtag aaaatgaaaa aaaatcgtgt atttgctaca
    12361 gcaggtcttg ttttattagc agcaggtgta cttgcagcat gcagttcttc aaaatcatct
    12421 gattcatcag cccctaaagc ttatggctat gtttatacag cagacccaga aaccttggac
    12481 tacctgattt caagtaaaaa tagtacaaca gtagtgactt caaatgggat tgatggttta
    12541 ttcactaacg ataattacgg taatcttgct cctgcagttg cagaggattg ggaagtctct
    12601 aaggatggtt tgacctacac ttataagatt cgtaaagggg ttaaatggtt tacctctgat
    12661 ggagaagaat atgcagaggt gacggctaaa gatttcgtga acggtttaaa acacgcagca
    12721 gataaaaaat cagaagctat gtatttagct gaaaattcgg ttaaaggctt ggcagattat
    12781 ctatcaggaa cttcaacaga tttttcaaca gttggtgtca aggcggttga tgattatacg
    12841 ttacaataca ctttgaacca gcctgaaccg ttctggaact ctaagttgac ctattctatt
    12901 ttctggcctc tgaatgaaga attcgaaaca tcaaaaggaa gcgattttgc taaaccaaca
    12961 gatccgacat ccttgcttta taatggtcca ttcttgttga aagggttgac tgcaaaatct
    13021 tctgtagagt ttgtaaaaaa tgagcaatat tgggataaag aaaatgtcca cctagatact
    13081 atcaatctag cttactatga tggatcagat caggagtcgc tagagcgtaa cttcactagt
    13141 ggagcttata gttatgcccg tctttaccct accagctcca actattctaa ggttgcagaa
    13201 gaatacaagg acaatatcta ttacacacaa tcaggctctg ggattgctgg tctgggtgtg
    13261 aatattgatc gccaaagtta caactatact tctaaaacta cagattcaga gaaagtagct
    13321 actaagaagg cattgcttaa caaagatttc cgtcaagcct tgaattttgc tcttgatcgc
    13381 tcagcttact cagctcaaat caatggtaaa gatggagcag ctttagcagt tcgtaattta
    13441 tttgtaaaac cagactttgt ttcagctggt gagaagacct ttggtgattt agtcgctgct
    13501 caacttcctg cttatggtga tgagtggaaa ggtgtgaatt tagctgatgg gcaggatggt
    13561 ttattcaatg ctgacaaggc caaggcagag tttgcgaaag ctaagaaagc tttagaagca
    13621 gacggcgttc agtttcctat tcatctggac gttccagtag accaagcatc aaaaaactat
    13681 atatctcgta ttcagtcctt taaacaatct gtagaaacag ttcttggtgt tgaaaatgtc
    13741 gttgttgata ttcaacaaat gacaagtgat gaattcctta atattactta ctatgctgcc
    13801 aatgcttcat ctgaggattg ggatgtatca ggaggagttt catgggggcc agactatcaa
    13861 gacccatcta cttacctgga tattttaaaa acaactagca gtgaaactac aaaaacatat
    13921 ttaggatttg ataatccaaa tagcccttca gtagttcaag ttggtttgaa agaatacgat
    13981 aaattagttg atgaagctgc caaagagaca agcgacttga atgtccgtta tgaaaaatat
    14041 gcagcggctc aagcatggtt gacagatagt tcactcttta ttcctgctat ggcttcttct
    14101 ggtgcagcac cagtgctttc acgaattgtt ccatttactg gagcttctgc gcaaacaggc
    14161 tctaaggggt cagatgttta cttcaaatat ttgaaattac aagataaagt ggtgactaag
    14221 gaagagtatg aaaaagctcg tgaaaaatgg ttgaaagaaa aagctgaatc aaatgagaaa
    14281 gctcaaaaag aattggcaag tcatgtgaag taaataattt ctaatagaac tttctctcca
    14341 tgaggagaag gttcttttgg gatttttaaa ggaaataata tgaaaaaata tatttttatg
    14401 cgtgttttgc ggtcattggt ttcgattttc ttagtaacga ctttgaccta cacgattatc
    14461 tataccttgg ttcctcgaaa attgattttc aagcaggatc ctaactataa taaaattgcg
    14521 acaacggctg ataaacgtga taactatgaa aatactgtgt ttgagcgtat gggctacatt
    14581 gagtattacg atactaaaga gttgcaagaa aaggcaagta gcatggattc ttctgtaaca
    14641 gtagaagcaa atgcgaccaa taaagctatt tatgaaaagt acatcaatca attaggtcat
    14701 ggttggactt tgggagaatt tactgaaagt ggtcaattct atgctactcg tgaaattcca
    14761 atttttgaac gtgtttttca cttctatgct aatttgattg acattgacca tacaaataaa
    14821 atccaagacc ctgaaaatcc agacttgaaa cgctaccttc gttttgaaaa tgatccagct
    14881 atcggatggt cattggtcgg ttcaggaact aaacataaat atctcttgta ctttaacagt
    14941 cagttcccat ttgttcatca aaactttgtg aacttgaatt taggtgactc ttacccaacc
    15001 tatgctaata caccagttct tcaggttatt actcaaggtc aaggacaaac caaaactgcc
    15061 caagttcagt tcccaacagg taagaaaacg tcttctgtaa atatttactc aagaacctac
    15121 aagtcaccta gtcaggctga ctctcgtgaa gtagctagct atgggaaaga tgatccttat
    15181 acagcgactg aaagtaatta ccaatatcca tctatgattg tcagctctgc tattactggt
    15241 ttgattggtt tggttcttgc ctatgctctt gccgtgccac ttggttcagc catggctcgt
    15301 ttcaagaaca cttggattga tagcctctca acagggactt tgaccttctt gcttgctctt
    15361 ccaacgattg ccttggttta catcgttcga ttgattggat catctattgc ccttccagat
    15421 tcattcccta tcttgggagc tggagattgg cgttcttacg ttttaccagc agtcatcctt
    15481 ggtttgttgg gtgctcctgt tacagccatt tggattcgtc gttacatgat tgacttgcaa
    15541 tctcaagact ttgttcgttt cgctcgtgca aaaggtttgt ctgaaaaaga aatttcaaac
    15601 aaacacatct ttaaaaatgc catggttccg ctggtttcag gaattcctgg tgccattatt
    15661 ggggttatcg gtggtgcaac ccttactgaa acagtcttcg ccttcccagg tatgggtaaa
    15721 atgttgattg actctgtaaa agcatctaat aactctatgg tcgttggtct tgtcttcatc
    15781 tttacatgta tttctatctt ctcacgtctt ttgggagata tttggatgac tattattgac
    15841 ccacgtatta aattgactga gaaaggaggc aaataatgtc tacaatcgat aaagaaaaat
    15901 ttcagtttgt aaaacgtgac gattttgcct ctgaaactat tgatgcgcca gcatattctt
    15961 actggaaatc agtgtttaaa caatttatga agaaaaaatc aactgtagtc atgttgggaa
    16021 tcttggtagc catcattttg ataagtttca tctacccaat gttttctaag tttgatttca
    16081 atgatgtcag caaggtaaac gactttagtg ttcgttatat caagccaaat gcggagcatt
    16141 ggttcggtac tgacagtaac ggtaaatcgc tctttgacgg tgtctggttc ggagctcgta
    16201 actccatcct catttctgtg attgcgacag tgattaactt ggttatcggt gtttttgtcg
    16261 gtggtatttg gggtatttca aaatcagttg accgtgtcat gatggaagtt tacaacgtca
    16321 tctcaaacat cccacctctt ttgattgtta ttgtcttgac ttactcaatc ggagctggat
    16381 tctggaatct gatttttgcc atgagcgtaa caacatggat tggtattgcc ttcatgatcc
    16441 gtgtgcaaat cttgcgctat cgtgacttgg aatacaactt ggcgtcacgt actttgggaa
    16501 caccaacctt gaagattgtt gccaaaaata tcatgcctca attggtatct gttattgtga
    16561 caaccatgac tcaaatgctt ccaagcttta tctcatacga agccttcttg tctttcttcg
    16621 gtcttggatt accgattaca gtgccaagtt tgggtcgttt gatttcggat tattcacaaa
    16681 acgtaacaac caatgcttac ttgttctgga ttccattgac aacccttgtc ttggtatcct
    16741 tgtccctttt cgtagttggt caaaacttag cggatgctag tgatccacgt acacatagat
    16801 aggagtagaa atgacaaaag aaaaaaatgt aattttgact gctcgcgata ttgtcgtgga
    16861 atttgacgtt cgtgacaaag tattgacagc cattcgcggc gtttcccttg aactagttga
    16921 aggagaagta ttagccttgg taggtgagtc aggatcaggt aaatctgttt tgacaaagac
    16981 cttcacaggt atgctcgaag aaaatggtcg tattgcccaa ggtagtattg actaccgtgg
    17041 tcaggacttg acagctttat cttctcacaa ggagtgggaa caaattcgtg gtgctaagat
    17101 tgcgactatc ttccaggacc caatgactag tttggacccc attaaaacaa ttggtagtca
    17161 gattacagaa gttattgtaa aacaccaagg aaaaacagct aaagaagcga aagaattggc
    17221 cattgactac atgaataagg ttggcattcc agacgcagat agacgtttta atgaataccc
    17281 attccaatat tctggaggaa tgcgtcaacg tatcgttatt gcgattgccc ttgcctgccg
    17341 acctgatgtc ttgatctgtg atgagccaac aactgccttg gatgtaacta ttcaagctca
    17401 gattattgat ttgctaaaat ctttacaaaa cgagtatcat ttcacaacaa tctttattac
    17461 ccacgacctt ggtgtggtgg caagtattgc ggataaggta gcggttatgt atgcaggaga
    17521 aatcgttgag tatggaacgg ttgaggaagt cttctatgac cctcaccatc catatacatg
    17581 gagtctcttg tctagcttgc ctcagcttgc tgatgataaa ggggatcttt actcaatccc
    17641 aggaacacct ccgtcacttt atactgacct gaaaggggat gcttttgcct tgcgttctga
    17701 ctacgcaatg cagattgact tcgaacaaaa agctcctcaa ttctcagtat cagagacaca
    17761 ttgggctaaa acttggcttc ttcatgagga tgctccaaaa gtagaaaaac cagctgtgat
    17821 tgcaaatctc catgataaga tccgtgaaaa aatgggattt gcccatctgg ctgactagga
    17881 ggaaggaaat gtctgaaaaa ttagtagaaa tcaaagattt agaaatttcc ttcggtgaag
    17941 gaagtaagaa gtttgtcgcg gttaaaaatg ctaacttctt tatcaacaag ggagaaactt
    18001 tctcgcttgt aggtgagtcc ggtagtggga aaacaactat tggtcgtgct atcatcggtc
    18061 taaatgatac aagtaatgga gatatcattt ttgatggtca aaagattaat ggtaagaaat
    18121 cgcgtgaaca agctgcggaa ttgattcgtc gaatccagat gattttccaa gaccctgccg
    18181 caagtttgaa tgaacgtgcg actgttgatt atattatttc tgaaggtctt tacaatcacc
    18241 gtttatttaa ggatgaagaa gaacgtaaag agaaagttca aaatattatc cgtgaagtag
    18301 gtcttcttgc tgagcacttg actcgttacc ctcatgaatt ctcaggcggt caacgtcaac
    18361 gtatcggtat tgcccgtgcc ttggtcatgc aaccagactt tgttattgca gatgagccaa
    18421 tttcagcctt ggacgtttct gtacgtgccc aagtcttgaa cttgctcaaa aaattccaaa
    18481 aagagctcgg cctgacctat ctcttcatcg cccatgactt gtcggttgtt cgctttattt
    18541 cagatcgtat cgcagttatt tacaagggtg ttattgtaga ggttgcagaa acagaagaat
    18601 tgtttaacaa tccaattcac ccatatactc aagccttgct ttcagcggta ccaatcccag
    18661 atccaatctt ggaacgtaag aaggtcttga aggtttacga cccaagtcaa cacgactatg
    18721 agactgataa gccgtctatg gtagaaatcc gtccaggtca ctatgtttgg gcgaaccaaa
    18781 ccgaattggc acgttatcaa aaaggactaa actagtaatg gttttataat ttccatgtca
    18841 atttttatgg aaatt
//
LOCUS       DAVMCN010000033        18805 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVMCN010000033 DAVMCN010000000
VERSION     DAVMCN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.033"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(281..1087)
                     /gene="yidA"
                     /locus_tag="VYP85_001375"
     CDS             complement(281..1087)
                     /gene="yidA"
                     /locus_tag="VYP85_001375"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1881874.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1100..2404)
                     /locus_tag="VYP85_001376"
     CDS             complement(1100..2404)
                     /locus_tag="VYP85_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1881875.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2476..2853
                     /locus_tag="VYP85_001377"
     CDS             2476..2853
                     /locus_tag="VYP85_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1881876.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2944..3276
                     /locus_tag="VYP85_001378"
     CDS             2944..3276
                     /locus_tag="VYP85_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1881877.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3288..4859
                     /gene="ffh"
                     /locus_tag="VYP85_001379"
     CDS             3288..4859
                     /gene="ffh"
                     /locus_tag="VYP85_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1881878.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5054..6337)
                     /locus_tag="VYP85_001380"
     CDS             complement(5054..6337)
                     /locus_tag="VYP85_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1881879.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6591..7304)
                     /gene="rsmG"
                     /locus_tag="VYP85_001381"
     CDS             complement(6591..7304)
                     /gene="rsmG"
                     /locus_tag="VYP85_001381"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1881880.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7398..7958
                     /locus_tag="VYP85_001382"
     CDS             7398..7958
                     /locus_tag="VYP85_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1881881.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7960..8859
                     /gene="htpX"
                     /locus_tag="VYP85_001383"
     CDS             7960..8859
                     /gene="htpX"
                     /locus_tag="VYP85_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1881882.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(9008..10567)
                     /locus_tag="VYP85_001384"
     CDS             complement(9008..10567)
                     /locus_tag="VYP85_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1881883.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10806..11122)
                     /locus_tag="VYP85_001385"
                     /pseudo
     CDS             complement(10806..11122)
                     /locus_tag="VYP85_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            11292..11834
                     /locus_tag="VYP85_001386"
     CDS             11292..11834
                     /locus_tag="VYP85_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1881884.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11834..12463
                     /gene="nth"
                     /locus_tag="VYP85_001387"
     CDS             11834..12463
                     /gene="nth"
                     /locus_tag="VYP85_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1881885.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12674..13195
                     /gene="pyrR"
                     /locus_tag="VYP85_001388"
     CDS             12674..13195
                     /gene="pyrR"
                     /locus_tag="VYP85_001388"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1881886.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13214..14137
                     /locus_tag="VYP85_001389"
     CDS             13214..14137
                     /locus_tag="VYP85_001389"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1881887.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14187..15266
                     /gene="carA"
                     /locus_tag="VYP85_001390"
     CDS             14187..15266
                     /gene="carA"
                     /locus_tag="VYP85_001390"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1881888.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15579..18755
                     /gene="carB"
                     /locus_tag="VYP85_001391"
     CDS             15579..18755
                     /gene="carB"
                     /locus_tag="VYP85_001391"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1881889.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5471 a         3619 c         4223 g         5492 t
ORIGIN      
        1 agtatcctaa tttgtataat tgattgtgtg tagattcagg gtcaatttga agagagtatt
       61 taaaatatct tgggaaatta taatttctcc ctgttttttg agtccaatct atgagtatga
      121 gttgcccagg agtaaggcca cattctaaat cgtttaggta aaaattgtta caatcagaat
      181 ttgtgtctct attatgatta ttttgtttta aattaaatag tttgctaaaa aaattcattg
      241 gattttattg ctaatcaatt cttattgaaa aatgatactt ttacagtacc catgttcgga
      301 tggcgtgggc aacgccggat tcgtcatttg ttttagtgat gtatttggcg atttttttga
      361 tttctggatt tccattttcc atgacaacgg ggtttccaac gacttccagc atggcacggt
      421 cattttcttc gtcaccgatt gccatggttt catctttggt caatccgagt ttttcagcca
      481 agtgagtaat agctgaaccc ttgtctacat tctttttaag gagttcgagg tagaaaggag
      541 cagatttgtt gatagagtag tgctcgtaaa attcggctgg tattttttca atcgcagcat
      601 cgagaatttc tggttcatcg atgaacatac acttgacaat ttccttgcca gccatttctt
      661 caggggtacg gtagaagata ggcatgctga cgagggttga ttcgtgtaca gtgtattttc
      721 cgatattgcg atttgcagta tagataccgt ccttggtaat ggcatgcatg tggacaccga
      781 gcttgcgact gaggaattcc atatccagat aatcctcata ggtcaaggat tcgctgataa
      841 tctcatggcc agtagcagtt tcttggacaa gggcaccatt gaaggtcacc acatagtcac
      901 cttggtctct caactgcaag tcgtccagaa gtttggcaac acctgcgatg gggcggccag
      961 ttgcaatcac gactttgaca ccagcttctt tggcatcttg gatggcagaa aagacttcag
     1021 gagtgatttc cttttggctg ttgactaggg ttccgtcaat atcgacggcg attagtttaa
     1081 tactcataaa tttcctcttt tagtttttat ttggggtaaa atgatcgttc tcaatcaagt
     1141 gtaaaaattg ctgggtgatg cttgcgaaga tgctgttttg gtctaacatt tctttcggga
     1201 aataaaagcg attatctccg tggcgacttc cagcaaggga ttggacgata ggggacaggc
     1261 tagagagttc tgccagttct ccattttttt gtaaaatctc aatctgtgtc cttggatttt
     1321 cagattcggg acggtaaata tcataaggga ggtcaaagtt cttatgaatg gcagtatagt
     1381 agtcgggatc aaagccgatg tcctcaacca attttctcat gctagcgagt tggtcttggt
     1441 cttcttgtga aaaggtaatg gatttaaaga ccttgcggtt gacaaagcga tgcgataaat
     1501 ctgcaagaat cttgtcagga ctggtcatcc aaagctggaa gtaggtattc atcacgccat
     1561 catccagagc cagatagtca gtcaaggtca catttttttc gaagaaaggc aggaggtgtg
     1621 gagaagttcg ggcaaagaaa tccttgtcct caggatagag ttccttggcg cgtttgagaa
     1681 gattctgtag gagaacttcc atggcgcgtg ttgcggggtg gaaataaacc tgcatgtaca
     1741 tctggtagcg actgaggacg tagtcttcga tggcgtgcat gccattgcgc tgaaaggcga
     1801 taccattttc gataggacga atgactcgga ggattcgagt caggtcaaat tccccatagg
     1861 atgctcctgt aaaataggag tcgcgcaaga gatagtccat gcgatctgcg tcaatctgac
     1921 tagaaatgag ctgcacgacc tgcttattag gataggtatg gtcaatgaca ctggccacct
     1981 tttctgggaa atcaggtgcc acttgtagca ggacttggtg aatctctgtc tcaggatttt
     2041 gaataatctc ctgagtaatg gcttcatggt ctgtatcaaa gagattttca aaagtatggg
     2101 agtaggcacc atgcccaagg tcgtgtagga gagcagcagt catggtcaag agagactcgg
     2161 caggattcca ttcctcagga tatttttctt cgaaaatctc tgtgatgcgt cgtgcaattt
     2221 catagactcc tagacagtga gagaagcgac tgtgttctcc accgtggaag gtataactgg
     2281 aagttcccag ttgtttgatc cggcgcaaac gctgaaattc ttttgtatta atcaagtcat
     2341 agatgatttg attattgaca tggatgtagt tgtgaacagg gtcacggaat actttttcgt
     2401 tcatatgacc attatagcaa aatcctgctc tttttggtaa aatagtagga caagagacaa
     2461 gaaagagggc ctgatgtgaa gattcggatg cgaaatacaa ttcagtttga tgagcagttg
     2521 gaagtaattg accagcttta tgatgtggaa gtgcatgaaa aaggagatta tagctacctg
     2581 cttttctata atgaggaaaa ggaaaaagta gtgattaaat ttcatggtca agaacttgtg
     2641 atgagtcgat tttccaatcc caagaccatt atgcgctttc taaaggatag tgatagttta
     2701 gcctatattc ccacacctat gggtatgcag gagtttatta tccaaacgaa tcgttatcaa
     2761 gtggatgggc aaaagattga actagattat caactacaaa atcaagaggg acatcccttt
     2821 gccagctatc aattggaaat tacttggggc taggcttatg tctttttcaa atttagctat
     2881 ctatcttctt ggatcggctt cctagtgtgg tagattaggc taatttttgg tataataaaa
     2941 gttatggaaa tcgaaaaaac caatcgtatg aatgcgctct ttgaatttta tgcggcgctt
     3001 ttgacagata agcaaatgaa ttatatcgag ctctactacg ctgatgatta cagccttgct
     3061 gaaattgccg aggagttcgg tgtcagtcgt caggctgtct atgacaatat caagcgaaca
     3121 gaaaagattc tggaagatta tgagatgaaa ttgcacatgt actcggacta tattgtccgc
     3181 agtcagattt ttgatcagat tttggagcgc tatcccaagg ataactttct gcaggagcag
     3241 atagaaattt taacaagcat tgataataga gaataagagg aagaaaaatg gcatttgaaa
     3301 gtttaacaga acgtttgcag aacgtcttta aaagtctacg taaaaaagga aaaatctctg
     3361 aatctgatgt ccaagaggca accaaagaaa ttcgcttggc cttgctcgag gccgacgttg
     3421 ccttgcctgt tgtaaaggac tttatcaaga aagttcgtga gcgtgcagtc gggcatgagg
     3481 tcattgatac acttaatcct gcgcaacaga ttattaaaat cgttgatgag gaactgacag
     3541 ctgttttagg ttctgatacg gcagaaatta tcaagtcacc taagattcct acaatcatca
     3601 tgatggttgg tttgcaggga gctggtaaaa caacttttgc aggtaagctg gctaacaaac
     3661 tcaagaagga agaaaatgcc cgtcctttga tgattgcggc ggatatttac cgtcctgctg
     3721 ccattgatca gctgaagaca ctgggacaac agattgatgt gccggttttc gctcttggga
     3781 cagaggttcc agctgttgag attgtacgtc aaggtttgga gcaagctcaa actaatcata
     3841 acgactatgt cttgattgat actgcgggtc gtttgcagat tgatgagctc ctcatgaatg
     3901 agcttcgtga tgtgaaagca ttggctcaac caaatgaaat cttgcttgtc gttgatgcta
     3961 tgattggtca ggaagcagcc aatgttgcgc gtgagtttaa tgctcagttg gaagtgactg
     4021 gggtcatcct taccaagatt gatggcgata ctcgtggtgg tgctgctctg tctgttcgtc
     4081 acattactgg aaaaccaatc aagttcactg gtacaggtga aaagattacg gacattgaaa
     4141 ccttccaccc agaccgcatg tctagccgta tccttggcat gggggatatg ctcactttga
     4201 ttgagaaagc ttctcaggaa tacgatgaac aaaaagccct tgaaatggct gagaagatgc
     4261 gcgaaaacac ctttgatttt aatgatttca tcgatcaatt agatcaggtg caaaatatgg
     4321 ggccgatgga agacttgctc aagatgattc caggtatggc caacaatcca gcacttcaaa
     4381 acatgaaggt ggatgaacgc cagattgctc gtaaacgtgc gattgtgtct tcgatgacac
     4441 ctgaagaacg tgaaaatcca gatttgttaa atccaagccg tcgccgtcgt attgctgctg
     4501 gttctggaaa tacattcgtc gaagtcaata aattcatcaa ggactttaac caggctaaac
     4561 agctcatgca gggtgttatg tctggggata tgaataaaat gatgaagcaa atggggatta
     4621 atccaaataa ccttcctaaa aatatgccaa atatgggagg aatggatatg tctgcccttg
     4681 aaggaatgat gggacaaggc ggtatgcctg acttatcagc tctcggagga gcaggaatgc
     4741 cagatatgag ccagatgttt ggtggcggtt tgaaaggtaa aattggtgaa tttgccatga
     4801 aacagtccat gaaacgtatg gctaacaaaa tgaagaaagc gaagaagaaa cgcaagtaag
     4861 acaagagatt gatgcaaatc tcatttgatg agaaaataaa gtaaaaattt ctatgataaa
     4921 acgtacagta tcaaggtttt agaatatctg atattatacg ttttttgatt ttaataattt
     4981 tgttaagaca cttttattat agtatacgaa aaatccactc agctgtctga gtggattagg
     5041 tgtatttaga ctcttagtct ttattttcgt atggcaagat caagttcaag atgattcctg
     5101 tcatggctga aagggcagta cctgaaagtg taactggacc aagtttaagg atagctcctc
     5161 caagtccaag aaccaacata gcacttgcga tgatgaggtt tcgcatttga gcgaaatcaa
     5221 cacgttcttt aatcaagact ttcaaaccat tgctggcgat aaccccatag agaaggattg
     5281 acataccacc aagtacagcg tttggaatag ttgaaatcaa ggcagtgaat ttaccaagga
     5341 agctgagggc aatcgcgatg aaggcagcgt tacggataac tgagacagaa gcgatacgag
     5401 tcataccgat aacccctgta ttttctccgt aagttgtatt ggctggtcca ccaaggaagg
     5461 cagaaacaga agttgcgata ccgtcaccaa taagagtacg gtgaagacct ggttctttta
     5521 agaattgacg gccacagatt tgacccaaaa cagtatggtc tccgatatgt tcagaaattg
     5581 ttacgatagc gattggcaag atagcgatgg cttctggacc aaagtaaaga ttgtactctt
     5641 taaaggcacc acctgtgcta aatggcaagt agaaaccagg aatttcaaac cagttagctt
     5701 ctaggacagg cgtaaagtca accaaaccaa gagttagcgc gaagaggtaa ccaccgataa
     5761 tggcaaagag gaatggaatg attcgtagga agccttttcc ttttgtattg ataaaggcag
     5821 caattaggaa agtaacaacg gctaccagag catttttcca atttccgtct gctacaagac
     5881 ctgcattggt aacagctgaa cctgcaagtc caagaccgat aacgatgatc ataggaccga
     5941 taatgattgg tggcaagagt ttatcaatcc attttgttcc tacaaatcgg atgctggtag
     6001 caacaaggac atagaccaaa ccagtcaaga taacccctgt ttgagcagca gatacatccc
     6061 cccccatttc tttcatagcc agtgacatag ctgtgataaa ggcgaatgaa gaacctagat
     6121 aaactggaac tttaaaacca gtagcaatca tgtagatgag tgttccaaca cctgaagcaa
     6181 aaagggcaac agatacaggc attcccaaaa tcaatggtac caagatggtc gcaccaaaca
     6241 tggcgaaaac gtgttggaaa ctaaggagaa ttccttttcc agccgaagga cgttggtcaa
     6301 cgtctagtaa caaatcaaca gttgattctt gtttcatata aacctcactt ttgggcatca
     6361 aaaaagagcc cattatttta cagcaatagg ccctcagagt aagacttctt taaaatttag
     6421 attttaaaga gttttaaata tttctgcgtc ttcgtcacct cacgggatga cattaaaaac
     6481 ctttgcttag gatagtatag cagaaaaaaa tgattttgta aatcattttt tcccgagcct
     6541 agaaataaaa gagcgaggct gattttgtaa acatttgttt actaaaaaat ttaaagtggg
     6601 cgtttatttg gcataccagc cttacgtgga tatttatttg gtgtttcttt tttcttttct
     6661 accactgtga tatagcgcgg atctctattc ggtagggcgt agctgagatt gtcttcgacc
     6721 ttactaaaaa ggagattgag ggcattctta gcttctaata attcctcagg cgcattgcta
     6781 gccttgagtg ctaatagttt gccaccaacc ttaaggtagg gaatagtcaa ttcagatagg
     6841 acctgcatac gggcaaccgc acgagctgtt acaaaatcat attgagcacg gaagttcttg
     6901 tcttgggcaa aatcttcggc acgtccgtgg tagaaatgaa ctccgttcaa atccagttct
     6961 tgagccaaga gttgtaggaa gttgatgcgc ttattgagtg aatcaataat ggtcacatct
     7021 aactccggat agagaatttt cattggtaga ctaggaaatc ctgccccagc cccgatatca
     7081 agaagtttga tagtttcatt gggaatcaaa ccttgaagaa tgggtgcaat cgaatcgtaa
     7141 aaatgtttga gataaacttc ttccttgtcc gtaatcgccg tcaaattaat cttctcattc
     7201 cactcgacca agagctcaaa ataacgttca aattgttctt tttgctggtc cgaaagtgga
     7261 agattctgct cggcaagcaa gttgtaaaat gtttttggtt tcatagttat ttccttcttt
     7321 agtatcatct tattttacca caatcataga aaatttgata tactggtact aatctaaaag
     7381 cagaaaggac ttatattatg acttggatta ttcttggagt tttagctctt gttgttattt
     7441 ttgtgattgt tagctataac ggtttggtta aaaatcgtat gcaaaccaag gaggcttgga
     7501 gtcagattga tgttcagttg aaacgtcgaa atgacctctt gccaaacttg attgagactg
     7561 taaaaggtta tgccaaatat gaaggttcta cccttgaaaa ggtggcagaa ctacgtaacc
     7621 aagtggcggc agcgacttca ccagcagaag ctatgaaagc cagtgatgcc ctcactcgtc
     7681 aggtttcagg tatttttgca gttgcagaaa gctatccaga tttgaaagct agtgctaact
     7741 ttgttaaatt gcaagaggag ttgacaaaca cagaaaataa aatttcttac tctcgtcaac
     7801 tctataacag tgttgtcagc aactacaatg taaaattaga aactttcccg agcaatatta
     7861 tcgctggaat gtttggattt aaagcggcag atttccttca aacacctgaa gaggaaaagt
     7921 cggttcctaa agttgatttt agcggtttag gtgactaaga tgttgtttga tcaaattgca
     7981 agcaataaac gaaaaacctg gattttgttg ctggtatttt tcctactctt agctcttgtt
     8041 ggttatgcgg ttggttatct ctttataaga tctggacttg gtggtttggt tatcgcactg
     8101 attatcggct ttatctacgc tttgtctatg atttttcaat cgacagagat tgtcatgtcc
     8161 atgaatggag cgcgtgaggt ggatgagcaa acggcaccag acctctacca tgtagtggaa
     8221 gatatggctc tggtcgctca gattcctatg ccccgtgttt tcatcattga tgatccagcc
     8281 ttaaatgcct ttgcgacagg ttctaatcct caaaatgcgg ctgttgctgc gacttcaggt
     8341 ctactagcta tcatgaatcg tgaagaacta gaagctgtta tgggacatga agtcagtcat
     8401 attcgtaatt atgatatccg tatttcgact attgcagttg cccttgctag tgctatcacc
     8461 atgctttcta gtatggcagg tcgtatgatg tggtggggtg gagcaggtcg cagacgaagt
     8521 gatgatgacc gagatggaaa tggtcttgaa atcattatgc tagtggtttc cctactagct
     8581 attgtactgg cacctctcgc tgcaaccttg gttcagctcg ctatttctcg tcagagggaa
     8641 tttctggcag atgcatctag tgtcgagctg actcgcaatc cccagggaat gattaatgcc
     8701 ctagataagt tggacaatag caaacctatg agtcgccacg tcgatgatgc tagcagtgcc
     8761 ctttatatca atgatcccaa gaaaggtggg gggttccaaa aactctttta tacccaccca
     8821 cctatctcag aacggattga acgtttaaaa catatgtaaa atgaaggctg gaaaaaagtc
     8881 tttaaaatct gaaaaacgca taatatcagg tgtgaaaact tgatattatg cgttttacta
     8941 tgggaagatt tacttctttt tctcctaaaa ttgtgttttt gccccaccta tctgctatgt
     9001 tgcaaattta taaatcttct aaattaacta gcttcaaacc gtgttctgtc atgcgataga
     9061 tgatcgagca gacttctttt aagaaacgac ggtcatgcga aacagtgatg agaccgccag
     9121 gataagtggc aaagagtttt ctgatttggg gttgagaagt gggagaaaag tttcgtgtgg
     9181 gttcatccag caggagaaag tttggtttgc gcaggactaa atccaaaagc aggagttttc
     9241 cctgttgtcc gccagataag gagcgaattt gatgctgcat ttctggataa ctgaaattga
     9301 gactagctag gtgagattgg attttctgta gttcctcttt ttccccagtt ttactgagat
     9361 aggctattgg ggataaatcc aattgcagtt ttttgtggta atcttgtggc ataaaaccaa
     9421 gtgaaatctc tcttttatca ttcagaagtc tctgtaactt ggctaacaga gttgatttcc
     9481 caacaccatt tggcccgata ataccgattt tttcttggcc acggacagtt agttgtagtt
     9541 tttgaaccaa aactcggtcg tcaatggaca aattttcttt ttccagttgg actaagactt
     9601 tagaagctgg taatggttgg atgtctgaaa agaaaagttg gatttgttcc tcttcaagtg
     9661 gcttttgagt catggactga gctgcctttt cgtagcgttt ttcttgtgag aggacagttt
     9721 tcatcttttt agccaatagg cgaccggcag tactatcttt ggtagctcga agcgcagttt
     9781 ctacactttg cttgactctc cgatgttttt ccatggtttt atcgtaggct ctttggttgt
     9841 tagcagcttg ctgactttgt ttggcaaaat tagcctttct ctgctcacta tagctatcat
     9901 agtctaaatg ctctactagc gtttccgctt ctttacggtg tttgaccagt cgcaagtgaa
     9961 caatagtgtc tgccgtttca gaaagaaagt cttcatcatg ggaaatgaaa ataacggttt
    10021 gcctggtctt ttgaatctgg ccttttagcc aatcaactgt ctcaaggtct aggtcatttg
    10081 aaggttcatc taaaaataga atctcaaagg gtttggctaa ctcatggata agctgaattt
    10141 tcaaagcttc gccccctgat agattgccaa tcttttggtc acttgcgaaa cgattgctat
    10201 caaaatgcaa ttcctccgcc aaacgataga ggatactgta gtctaaatca atagaatcta
    10261 aaaagaagta gtcgtgtaaa gttttctttt tcagctcctc gggaagtttt tgaggaatgt
    10321 aggccagtga ctgatagtca gattggatgt ttcccttgat agtgaaatca gacaaagctt
    10381 cccccattaa aattttaagt aaggttgatt tgccatttcc ttcttcacca ataatagcaa
    10441 ccttttcccc gtcttggatg gtcatgctta ggtcagatac aagatctcgt aaatctttgt
    10501 tttgtgtgat ggttagatga ttgattttta tcatatgatt tccctttcta gaatgttcat
    10561 agtgcataac aaaaagctct actttaccta gtagagccca aagtctatgt caaaaaaact
    10621 ctattaacat gccagaaaaa gagcataaaa gagcacacaa aaagagacaa aaacaagatc
    10681 tactaaataa aggttcttta tttgatagac ttagttgttc atgtctccct tacctccgag
    10741 tattagtatc tttatattat acctttaagg aaattttgtc aacagaaaac tggaaattct
    10801 atgctctaaa atccaaaaac aggtccatag agacttagta cgtgtttgac atgctcgtaa
    10861 tggaatttat catagtttcg ccaagcagtg cgtgcttgat cgtttagttt taggctaccc
    10921 agtccaatca gaagactggt gggttggtaa aatttctcaa gatcaattaa gatactgttg
    10981 ttcaactttt ccgttttttg agctcttgca tagtagtgtt tagcagctct tgtagtcgaa
    11041 tatcatctgc cgtaccctgt ttacagtttt ggtagctttt atttaacttg gataggagtt
    11101 gaatgagttt cttgtcttcc atgtgagcat cctccttgat ctgatgtact ctttccctat
    11161 agtatagcac taaaaaacaa aactgtcata gtaaatatgt taaaattttg aattttaatt
    11221 acaaagtttg gtgtgctgat ttgtagcctt ttcatggtat aatcaagaga gtaaatcttt
    11281 atggaggaag tatgaaatta aatattcaag aaattcgtaa gcagtctgaa ggtttgaact
    11341 ttgaacaaac gttagattta gttgatgacc tgcgtgcacg taatcaagaa attttagatg
    11401 taaaagatat ccttgcagtt gggaaagtac aatatgaaga ccgtatgtat ttcttagatt
    11461 atcaactatc ttataccatt gttcttgctt cgagtcgcag tatggagcca gttgagttag
    11521 ttgaatctta tccagtcacg gaagttttca tggaaggcgc aactaaccat ctaaatcaag
    11581 aaattttaga tgatgacttg gtcttgccca tcgaaaatga ggcgcttgac cttgctgaga
    11641 gtgtatcaga caatatcttg ctaaacattc ctatcaaggt cttgacggct gaagaagaag
    11701 ctggtcaagg atttgtctca ggaaatgact ggcaaatcat gacagaggaa gaataccaag
    11761 ctcaacaagc agtaaagaaa gaagaaaaca gtccttttgc tggcttacaa ggactatttg
    11821 acggagatga ataatggtct tgtcaaaaaa acgagcacga aaggtgctag aagaaatcat
    11881 tgccctcttc ccagatgcca agcctagtct tgattttacc aatcattttg aactcctggt
    11941 tgcggtcatg ttatcagccc agacgacaga tgcagcggta aataaggcca caccaggtct
    12001 ctttgttgcc tttccaacac cccaagctat gtctgtagcg acagagagtg agattgcttc
    12061 acatatttct cgcttgggat tgtatcggaa taaagctaaa ttccttaaaa aatgtgccca
    12121 acagttacta gacgattttg atggtcaagt ccctcagaca cgtgaagaat tggagagttt
    12181 ggcaggtgtt ggtcgcaaga cagccaatgt tgtcatgagt gtaggatttg ggattccagc
    12241 ctttgcagtg gatactcatg tggagcgtat ttgcaaacac cacgatattg tcaaaaaatc
    12301 agcgacgcca cttgaggtgg aaaagcgggt catggatatc ttgccgcctg agcagtggtt
    12361 agctgcccat caggccatga tttattttgg aagagccatt tgccatccaa aaaatccaga
    12421 gtgtgaccag tacccacaat tatatgattt tagcaatttg taagatgcta cattgaaact
    12481 ttttgcttga ttttaagcat gctttgtgct atagtaaatg ataactaaat attcctttaa
    12541 acctgtcccg tgaggcaggc aaggagcgcg ataaagtaga agggtgaagt ctatactgtg
    12601 tgcagtaggg ctcgcttggc tataaatttc aagtctcctt gtttaaggag acttttcttt
    12661 ttggaggttt gtcatgaaaa caaaagaagt tgtagacgaa ttgaccgtca aacgagcgat
    12721 tacgcgtatt acttatgaga ttatcgaacg caacaaagat ttgaataaga tcgtcttggc
    12781 tggtattaaa actcgtggtg tctttattgc ccaccgaatc caagaacgtt tgaagcagtt
    12841 agaaaatctt tcagttcctg ttgtggaatt ggatactaaa cctttccgtg atgatgttaa
    12901 aagtggagaa gatacttctt tggtttctgt cgatgtgaca gaccgcgaag ttatcttggt
    12961 ggatgatgtg ctctatacag gtcgtaccat ccgtgctgct attgataata ttgtcggtca
    13021 tggtcgtcct gcgcgtgtga gtttagcagt tctagtcgat cgtggacata gagaattgcc
    13081 aatccgtcca gattacgttg gaaaaaatat cccaaccagt cgttctgaag aaatcatcgt
    13141 agagatgaca gaacttgatg accaagacag agttctgatt actgaagaag cttagaaagt
    13201 taaaggagta gccatgtcag aaaatcaaca agcattgaac catgtggtgt ccatggaaga
    13261 cctcactgtc gatcaagtaa tgaaattgat caagcgagga attgagttta aaaatggagc
    13321 ccagcttccc tatgaagacc atccgattgt ttccaatctc ttctttgagg attctacacg
    13381 gacacataag tcctttgaag tcgcagagat taaacttgga ttggaacgac ttgactttga
    13441 tgtgaagact agttcggtta ataagggtga gacactttat gacaccattt tgactctgtc
    13501 tgctttagga gtggatgtct gtgtgattcg ccatccagag gtcgactact atagagaatt
    13561 gattgctagt ccaacgatta cgacttccat catcaatggt ggagatggtt cgggccaaca
    13621 ccctagccag agcttgcttg atttgatgac catttatgag gaatttggcc actttgaggg
    13681 tcttaaagtt gctattgcag gtgacttgga ccactcacgc gttgccaaat ccaatatgca
    13741 gattttgaaa cgcttgggat ctgaactctt tttcgctgga cctgaggaat ggagaagtca
    13801 agagtttgca gactatggac agtttgtaac cattgatgaa atcattgatc aggttgatgt
    13861 catgatgttt ctccgtgtgc aacacgaacg ccatgatagt ggagctgtat tttcaaaaga
    13921 agactaccat gcccaacatg gcttgactca agaacgttac gatcgtttga aagaaacagc
    13981 aatcctcatg cacccagctc caatcaatcg tgatgtagaa atagcagacc acttggttga
    14041 agcaccaaaa tcacggattg tccaacaaat gaccaatggt gtctttgttc gaatggcaat
    14101 cttagaatcc gtactagcga gtagaaacgc caactaaaac acaagacgtt aaaagacgcc
    14161 agtgagcgtc cacgagaggt gaaaatatga caaaaagaat tctagtatta gaagatggca
    14221 cagtttttga aggcaaggcc ttcggagcag atattgatgt aacaggcgaa atcgtcttta
    14281 atacagggat gaccggctac caagaatcca ttacagacca gtcttataat ggacaaatct
    14341 tgacctttac ttatcctttg gtaggaaatt atggtattaa tcgtgatgat tatgaatcca
    14401 ttattccaac ttgtaaggga gtcgttgttt ttgaagaagc gcgtagagct agcaactggc
    14461 gcaaccaaat gaccttggat gaatttttga aagccaagaa aattccaggg atttcaggaa
    14521 ttgatacgcg tgctcttacc aagattatcc gtaagcatgg tactatgcgt gcaaccttga
    14581 cccatgttgg ggacagtatg gaccatgtga cggaccagct ccaagcaaca gttttaccga
    14641 cagacaatat caaacaggtt tctactaaaa cgtcttatcc agctccagga gttggtttga
    14701 gcgtggtgct agtggacttt ggtctcaagc actcaatcct acgtgaactt tctaaacgca
    14761 actgtaacgt gacagttgtt ccttattcga caacggctga agaaattctc catctcaatc
    14821 ctgacggagt tatgttgtca aatggtccag gtaacccaga agacgttcca caagcactcg
    14881 acatgattcg cggtgtacaa ggaaaaattc caatctttgg tatttgtatg ggacaccaac
    14941 tctttgcaat ggcaaacggg gctaagacct ataagatgaa gtttggccac cgtggattca
    15001 accatgcggt acgtgaaatc gcaacaggac gagtagactt caccagccag aaccatggtt
    15061 atgcagtcag ccgcgaggat ttgccagagc acttgattat tacccacgaa gaaatcaatg
    15121 acaagtcagt ggaaggtgtg cgccacagat accaacctgc tttctctgtt caataccacc
    15181 cagatgcagc tcctgggcca cacgacgcta gctacctatt tgacgagttt atcgagatga
    15241 tggaagtttt taaacaatca aactaagaac gagtaaaagc tcgtcggaga atttatgtaa
    15301 ctgaacacgg acggaaagct cagaatgtag agaaaccaac ttggattgtc aatccttcct
    15361 tgatttccta aaattcaatc gctttctatt cgtcctttgt atcttattta atgtcgccct
    15421 gagaggcgac gaatagaaag gagaagggtg ctccgtattt gctgaactga atacgggcta
    15481 cggacggtgc taaaaagata gttattccta gaactgacag ttcttcgtca taactcctat
    15541 tttagctttg tccgcttgac acccttaata tcttatatat gcctaaacgt actgatattc
    15601 aaaaaattat ggtgattggt tctggtccga ttattattgg tcaggctgct gagtttgact
    15661 acgctgggac tcaggcttgc ttgtcgttga aagaggaagg ttatgaggtt gttttggtta
    15721 actcaaatcc tgcaaccatc atgacggaca aggaaattgc tgacaaggtt tacattgaac
    15781 cgattacact tgagtttgtg acacgtattc ttcgtaagga aggtccagat gccttgctac
    15841 caacactcgg tggtcagaca ggtctcaaca tggccatgga attatctaaa aatggtatcc
    15901 tagacgagct tggcgttgaa cttctgggta ccaaattatc tgccattgac caagcggagg
    15961 accgtgacct ctttaaacaa ttgatggaag agcttgaaca acccattcca gaatctgaaa
    16021 ttgttaacac agtagaagaa gcagttgcct ttgcagcgac aattggctac ccagtcatcg
    16081 ttcgtccagc ctttaccctt ggtggtactg gtggtggtat gtgtgccaac gagaaagaat
    16141 tgcgtgaaat cactgaaaat ggtttgaaat tgtcacctgt tacccaatgt ttgattgagc
    16201 gttcgattgc cggtttcaag gaaattgaat acgaagtgat gcgtgactca gctgacaatg
    16261 ccttggttgt ttgtaacatg gaaaactttg acccagttgg gattcacaca ggggattcca
    16321 ttgtatttgc ccctgcgcaa accatgtcag actatgaaaa ccaaatgctt cgtgatgcga
    16381 gcttgagcat tattcgtgcc ctcaagattg aaggtggatg taatgttcag ctagctcttg
    16441 atcctaacag cttcaagtat tatgttatcg aagtaaaccc tcgtgtatca cgttcgtcag
    16501 cccttgcttc taaagcgaca ggatatccga ttgctaagtt ggctgccaag attgcagtag
    16561 gtttgacctt ggatgaggtt ataaacccag ttacaggttc aacctatgcc atgtttgaac
    16621 cagcccttga ctacgtagtt gctaagattc cacgtttccc atttgacaag tttgaaaagg
    16681 gtgaacgccg tctcggtaca caaatgaagg cgactggaga agtcatggca atcggtcgta
    16741 acatcgagga atctcttctc aaggcctgcc gctcccttga aattggggtg caccacaatg
    16801 aaatacctga acttgcagca gtttctgatg atgccttgat tgaaaaggtt gtcaaagccc
    16861 aagatgaccg tctcttctac gtatcagaag ccattcgtcg tggctacaca cctgaagaaa
    16921 ttgcagagct tacaaaaatt gatatcttct atcttgataa actcttgcat atctttgaaa
    16981 ttgagcaaga attgggtgct catccacaag atttagaagt tttgaaaaca gccaaactta
    17041 atggtttttc agaccgtaag attgctgaac tctggggaac gactgatgat aaagttcgcc
    17101 aacttcgctt ggaaaacaag attgttccag tttataagat ggtagacact tgtgcggcag
    17161 agttcgactc cgaaacgcca tatttctatt caacctatgg ttgggaaaat gaatctatca
    17221 gatctgataa agaatctgta cttgtcctag gttcaggtcc aatccgtatc ggtcaagggg
    17281 ttgagtttga ctacgcaacc gttcactctg ttaaggctat ccaggcagct ggttatgaag
    17341 ctatcatcat gaactcaaac ccagagaccg tttcaacaga cttctctgta tcagataagc
    17401 tttactttga gccattgaca ttcgaagatg ttatgaacgt cattgacttg gaacaaccaa
    17461 agggagttat cgttcagttc ggtggtcaaa cagccatcaa ccttgcggag ccattggcaa
    17521 aagcaggtgt gaccatcctt ggtacacagg ttgctgacct agatcgtgcc gaagaccgtg
    17581 acctcttcga gcaagctctc aaagaattgg atattccaca gccaccagga caaacggcta
    17641 ccaatgaaga agaagcagct cttgcagctc gtaagattgg cttcccagtt cttgtccgcc
    17701 catcttatgt acttggtgga cgtgccatgg aaatcgttga aaacgaagaa gaccttcgtt
    17761 cttacatgcg aactgctgtt aaggctagtc cagaccaccc agttcttgtc gactcttata
    17821 tcgttgggca agagtgcgaa gttgatgcca tttcagatgg taaaaatgta ctcattcctg
    17881 gtatcatgga gcatatcgaa cgtgctggtg tccactcagg tgactcaatg gctgtttacc
    17941 caccacaaac cttgtcgcaa aaggttcagg agaccatcgc agactacacc aaacgcttag
    18001 caatcggtct tcactgcctt ggaatgatga acatccagtt tgttatcaag gatgaaaaag
    18061 tctacgttat tgaggtcaat ccacgtgcca gccgtactgt tccattccta tctaaggtaa
    18121 ccaatattcc tatggctcaa gtagcgacca aactcattct tggtcaaagt ttatcagaac
    18181 ttggctacca aaatggactt taccctgaaa gcacccgtgt tcatatcaag gcacctgtct
    18241 tctcctttac caaactagct aaggtagaca gcttgctcgg tcctgaaatg aagtcaacag
    18301 gtgaagttat gggttctgat gctactttgg aaaaagctct ctataaagcc tttgaagctt
    18361 cttatctaca cttgccaact tttggtaatg tcgtctttac catcgctgat gatgccaaag
    18421 aagaagcctt gaacttggct cgtcgtttcc aaaacattgg ttatggaatc cttgcgacag
    18481 aagggacagc agccttcttt gctagtcatg gcttgcaagc ccaacctgtt ggtaagattg
    18541 gtgatgacga taaggatatc ccaagttttg tacgcaaagg aagaattcaa gctatcatta
    18601 acacagtagg aacaaaacga actgctgacg aagatggtga gcaaattcgt cgttcagcca
    18661 ttgaacacgg ggtgcccctc ttcacagcgc tagatacagc taatgccatg cttaaggtac
    18721 ttgaaagtcg tagctttgtt acagaagcga tttaaataga aaaaataaga tatagcagcc
    18781 tgaatttaga acagtacaca gggat
//
LOCUS       DAVMCN010000034        17994 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVMCN010000034 DAVMCN010000000
VERSION     DAVMCN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.034"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VYP85_001392"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VYP85_001392"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1881890.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VYP85_001393"
     CDS             1377..1886
                     /locus_tag="VYP85_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881891.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETLAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4368
                     /locus_tag="VYP85_001394"
     CDS             1963..4368
                     /locus_tag="VYP85_001394"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1881892.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQDTEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPLVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4436..5437)
                     /locus_tag="VYP85_001395"
     CDS             complement(4436..5437)
                     /locus_tag="VYP85_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1881893.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5593..6040
                     /locus_tag="VYP85_001396"
                     /pseudo
     CDS             5593..6040
                     /locus_tag="VYP85_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6166..6423
                     /locus_tag="VYP85_001397"
     CDS             6166..6423
                     /locus_tag="VYP85_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881894.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVRLEQ"
     gene            6693..8942
                     /gene="metE"
                     /locus_tag="VYP85_001398"
     CDS             6693..8942
                     /gene="metE"
                     /locus_tag="VYP85_001398"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1881895.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLDTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9006..9872
                     /gene="metF"
                     /locus_tag="VYP85_001399"
     CDS             9006..9872
                     /gene="metF"
                     /locus_tag="VYP85_001399"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1881896.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10557..12770
                     /gene="pnp"
                     /locus_tag="VYP85_001400"
     CDS             10557..12770
                     /gene="pnp"
                     /locus_tag="VYP85_001400"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1881897.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12786..13403
                     /gene="cysE"
                     /locus_tag="VYP85_001401"
     CDS             12786..13403
                     /gene="cysE"
                     /locus_tag="VYP85_001401"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1881898.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13415..14299
                     /locus_tag="VYP85_001402"
     CDS             13415..14299
                     /locus_tag="VYP85_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1881899.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14381..15724
                     /locus_tag="VYP85_001403"
     CDS             14381..15724
                     /locus_tag="VYP85_001403"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1881900.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETVRKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            15717..16103
                     /locus_tag="VYP85_001404"
     CDS             15717..16103
                     /locus_tag="VYP85_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1881901.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16107..16991
                     /locus_tag="VYP85_001405"
     CDS             16107..16991
                     /locus_tag="VYP85_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1881902.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17233..17832
                     /locus_tag="VYP85_001406"
     CDS             17233..17832
                     /locus_tag="VYP85_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881903.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYAPLNDVTKYAR"
BASE COUNT         5417 a         3487 c         4078 g         5012 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagta gtaattgaat aggaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctggc tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga ctgctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaat gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggggccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggct ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaaccct tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagccttt tataaccgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag agaattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttgt atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggga tcgaggtaga gggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcagatt
     2161 aacgttggcg aagaagaaga gcgtcagatc gtttgtggtg ccccaaatgt gcgtgctggg
     2221 atcaaggtca tggtggctct tccaggagct cgtatcgctg ataactacaa aatcaaaaaa
     2281 ggaaaaatcc gtggtttgga gtcacttgga atgatctgtt cacttggtga attgggaatt
     2341 tctgactcag ttgtgcctaa ggaattcgca gatggcatcc aaatcttgcc tgaagatgcc
     2401 gtgccaggtg aggaagtctt ttcttaccta gacttggatg atgaaatcat cgaactttcc
     2461 atcacaccaa accgtgcaga tgccctttct atgtgtggag tggctcacga agtggcagcc
     2521 atctatgaca aggcagtcaa ctttaaaaaa tttactctaa cagaaactaa tgaagctgcg
     2581 gcagatgccc tttctgtcag cattgagaca gacaaggcgc cttactatgc agctcgtatc
     2641 ttggacaatg tgactatcgc accaagtcca caatggttgc aaaaccttct catgaacgaa
     2701 ggcatccgtc ccatcaataa cgttgtagac gtgacaaact acatcctgct ctactttggt
     2761 caacctatgc atgcttttga cttggacaca tttgaaggga ctgacatccg tgttcgtgaa
     2821 gcgcgtgatg gtgaaaaatt agtgaccctg gacggtgaag agcgagactt ggctgagaca
     2881 gacctcgtga ttacagttgc tgacaaacca gtagcccttg ccggtgttat gggtggtcag
     2941 gatacagaaa tttctgaaaa atctagtcgt gttatccttg aagctgctgt ttttaatggc
     3001 aaatctatcc gtaagacaag tggtcgcctg aaccttcgtt ctgagtcatc ttctcgcttt
     3061 gaaaaaggaa ttaatgtggc aacagttaat gaagcccttg atgcggcagc tagcatgatt
     3121 gcagagcttg caggcgcgac ggtgcgtaag ggtatcgttt cagcgggtga gcttgatacc
     3181 tctgatgtgg aagtttcttc aacccttgct gatgttaatc gtgtcctcgg aactgagctg
     3241 tcttatgctg atgtagaaga cgtcttccgt cgtcttggct ttggtctttc tggaaatgca
     3301 gacagcttta cagtcagcgt accacgtcgt cgttgggata tcacaatcga agctgatctc
     3361 tttgaagaaa tcgctcgtat ctatggatat gaccgcttgc caaccagcct tccaaaagac
     3421 gatggtacag ctggtgaatt gactgtgaca caaaaactcc gccgtcaagt tcgtaccatt
     3481 gctgaaggag caggtttgac agaaatcatc acctatgctc tgacaactcc tgaaaaagca
     3541 gttgagttca cagctcaacc aagtaacctt actgaactca tgtggccaat gactgtggat
     3601 cgttcagtcc tccgtcaaaa tatgatttca gggatccttg ataccgttgc ctacaacgtg
     3661 gctcgtaaga acaaaaactt ggccctttac gagattggaa aagtatttga acaaacaggt
     3721 aatccaaaag aagaacttcc aaatgagatc aacagctttg cctttgcctt gacaggcttg
     3781 gttgctgaaa aagatttcca aacagcagca gttccagttg atttcttcta tgctaaagga
     3841 atcctagaag cgctctttac tcgcttggga ctagaagtga cctatacagc aacagctgag
     3901 attgccagcc ttcacccagg acgtacagca gtcatttcac tcggtgacca agttcttggt
     3961 tttcttggcc aagtgcatcc agtcactgct aaggcctacg atattccaga aacgtatgtg
     4021 gctgagctta acctttcagc tatcgaagct gcgcttcagc cagcgactcc acttgtagaa
     4081 atcaccaaat tcccggcagt cagccgtgac gttgcccttc tcctcaaggc agaagtgact
     4141 catcaagaag ttgtagatgc tatccaagct gccggcgtga aacgtttgac agatatcaaa
     4201 ctctttgacg tcttctcagg tgaaaaactg ggacttggta tgaagtcaat ggcttatagc
     4261 ttgaccttcc aaaatccaga agacagctta acggacgaag aagtcgcacg ctacatggaa
     4321 aaaatccaag cgtctctcga agaaaaagtc aatgcagaag tgcgttaaac gatagtagga
     4381 tacaaattcc ccctctagtt tatgaacact agaggggtga ttttatataa aataattaaa
     4441 atgtgatttc tgtaaaaata catctatgat cagagttttg aaaacttaca atgtctaaat
     4501 ctttaacata gtagtggttt ttaggcaata aaatatgatc tattgttgca ttaaaaagtt
     4561 ttggactttg gctattccaa gttcctcttt caaaaggtgg aagtgcattc aatgcgtccc
     4621 tatgagagct tatttttgca agtgctccat gacgcatagt tgcattaaaa tcacctgcaa
     4681 taatagcctt tggatatttt gaagccaatt gattatgaat gatgtttaag tcttgcttcc
     4741 agatttccat taaacctggc agaggaggag cagtatgcaa ggcaatgata tctggtatat
     4801 tttgttttct cgaatgtaat acaattgtcc cgaaccgtgt tgtatgaaaa gttttagctt
     4861 ctgtatagaa accataactt ttcttgacaa tcacagtcac aggagctatt ccactattgg
     4921 taggtggaga agtgaaaata tcatagttgg ccatagaaag tccaacttga tgaaacaata
     4981 gtttgattct ctggttttct tgctcacctc tgatattggt agctagttca gggaatatag
     5041 ccatatcggc atcaaaatgg ctaaaaattc gctcaatatg ttgtgcttct atttgattag
     5101 cgacgttcca agttactaat tttaaggttt tagtcttatt tgatgcagaa gaaagggttt
     5161 tatctgttcc gaataatagt aatatgagcg atagtaagag caaaatgcca gagtaaaacc
     5221 gtatttgttt atttttcttg taaaaagata gggaaaaaaa tacgaaactt aaaatagaag
     5281 ccatagttgc agtagctaag gggaaggcat aaatctgtgc caagataggt ctggtagata
     5341 gccaaatatt aagattagaa gatgggaaaa aagaataagt tatgataggg atagaaaaga
     5401 gaatgaccga aagggcagag agaaatgttt taatcattgt gtgagtacct caatttgcaa
     5461 tggttgctcg gagctaatgt gactttgtga ctttacttga ttgatattct ttttcttgtc
     5521 ttccttatag attaagtaca acccaagtaa aaaaagtcca atttaagatt gaaatgatta
     5581 aaaggcacag agatgcaaga caattatact acaaaaggta aacatttgac aatcgatagc
     5641 cgtcgcttaa tcgaaagatg gaaaaaagaa ggaaaatcaa atagagaagt tgcctctcta
     5701 cttggaaaag ctcctcaaac tatccacact gaaatcaagc gtgggacagt ccgaaaatgt
     5761 cttggaaaag ggcgcttcaa agaggtttat tctgccgact acgctcaaca gtcttatgaa
     5821 aacaatcgca agcgctcggt caagaaatca agcttgacca aggaactaaa ggaaaagatt
     5881 ctccactata cataaccaaa aattttcgcc tgaaatgatg gtgatggcta aaggggttaa
     5941 cgtgggaatt tcaaccattt actattggat tcatcgtgga aaattggggt taagcaagca
     6001 ggatctgctt tatcctagaa aaggaaaatc gcttaagaaa taggctagca ccaactttaa
     6061 acccgctggt caatctatcg aatcataatt cgctcatttt tttaaaaata catagacgta
     6121 aaagaaagag ggttaagtga tgaagaatag tgctattggg agtaattgga aggatgtcca
     6181 tctgagctct ttagcaagga ggaaatcctt gaaagtgata tgcgagtggc tatcatgagc
     6241 gagttgattg aggctaggta tgaacaagga atcagtcaga aaaagctgga agaagtcagt
     6301 ggaataagcc agcctgtcat agctaggatg gagacaggaa agactagtcc tcagttggat
     6361 acagtcttaa aagtcctagc cagtttagga aagacactag cagtcgtccg acttgaacag
     6421 tgaaaaagtt gactagaatc agttatagtc ttttctaata acaagccata gtcacttata
     6481 agaattacta ataacgcgtt tgaaccgtct aactgaaata aagctataaa acaagctata
     6541 caaaggattt gagacgtttg cttcaagtct ttttcttttg tccgaaacag atatatagtt
     6601 tcaaactata tcaaacccta attttttaca attatacaga cgctttcttt tctgttaaga
     6661 tagtttcaac aacaaatttt ggaggacaca tcatgtcaac tacaatcatc ggtttccctc
     6721 gtttgggcga attccgtgaa ttaaaattta caactgaaaa atactttaga aaagaaatct
     6781 cagaagaaga acttttagca gcagcaaaag acttgcgtgc taaacactgg aacattgtca
     6841 aagaaaaagg catcactgaa attccatcaa atgacttttc tcactatgat aacttcctag
     6901 atgcggcttt ccttttcaac gtggtgcctg catccgttca aaacttggac ttgtctgacc
     6961 ttgagcgcta cttcgctttg ggacgtggtt accagggaga aaaaggggac gttcgcgccc
     7021 ttccaatgaa gaaatggttc aacactaact accactacat cgttcctaaa tttgaaaaag
     7081 acactcaagt aaaattggct ggtcacaaga ttttcgatga gttccaagaa gcaaaagaac
     7141 ttggattgga cactcgtcct gttcttgtag gtccattcac tttccttcaa ttgtcagact
     7201 ttgaagaagg cgtgaaagca gacgacttcg tagatagctt tgtggctgct taccaagaag
     7261 tttttgctaa attggctgac cttggtgcga ctcgcatcca attggatgaa gcggctcttg
     7321 taaaagactt gacagctgaa gaaaaagctc tcttcttgaa cctttacaac aaactcttgg
     7381 ctgacaaaaa aggtcttgaa gtcttgtttc aaacttattt cggtgatgtt cgtgacgtat
     7441 acgctgacct tgtaaacttg ccagtagatg ctatcggtct tgactttgtt gaaggtaaga
     7501 aaactcttga actcgttaaa ggtggcttcc cagctgacaa gactctctat gcaggtattg
     7561 tcaatggtaa aaacatctgg cgcaacaact acgaaaagag cttggctgtt cttgagcaaa
     7621 tcccagctga aaacatcgtt ttgacaagct cttgctcact tcttcatgtg ccatttacaa
     7681 ctgctaatga agaatttgaa ccagcactct tgaaccactt tgcctttgca gttgaaaaat
     7741 tggatgaaat ccgtgacttg gatgctatcc gcaatggtca aggttcagaa gctcttgcag
     7801 ccaacaaaga actctttgcg actgagcgtg ttggtgaaaa tgctgaactt cgtgcgcgta
     7861 tcgctggctt gacagacgca gactacactc gtttgccagc ctttgcagaa cgtgaagcta
     7921 tccaagaaga agctttcaaa cttccagctc ttccaacaac aacgattggt tcattccctc
     7981 aaacaaaaga agttcgtgcc aaacgtttgg cttaccgtaa aggtgaattg tctcaaaaag
     8041 agtacgacgc tttccttgct gaaacgattg acgaatggat caagtggcaa gaagatattg
     8101 actttgatgt ccttgttcac ggtgaatttg agcgtaatga catggttgag tacttcggtc
     8161 aaaacttgtc aggatacctc ttctctaaaa atggatgggt acaatcatac ggtatgcgtg
     8221 gggtaaaacc accaatcatc tggggtgatg tcactcgtct taaccctatc actgttaaat
     8281 ggtctagcta tgcacaaagt cgtacaaaca aacctgttaa aggtatgttg actggacctg
     8341 ttaccatcct taactggtca ttcccacgtg aagacatctc tatcaaggat tcaactctcc
     8401 aaatcgccct tgctatcaag gatgaagtac ttgaccttga agctgctggt gtgaaaatca
     8461 tccaaatcga cgaggctgct cttcgtgaaa aattgccact ccgccgtagc gactggtacg
     8521 aagactacct tgactgggct attcctgcct tccgcttggt acactcaaca gtagcgccag
     8581 acacacaaat ccacactcac atgtgttact cagaatttac agatatcatc ccagctatcg
     8641 ataacatgga tgcagacgtt atttcctttg aagctagccg ttcaaacctt gaaatcttgg
     8701 acgaactcaa agcgaaaaac ttccaaacag aagtgggacc tggggtttac gatatccact
     8761 cacctcgtgt accaaatgaa ggcgaaatcg acaacacaat cgaagccatc cttgctaaag
     8821 tgccaagcaa gaaagtttgg atcaaccctg actgtggttt gaaaacacgt ggtatcccag
     8881 aaacaaaaga aagcttgatc cgccttgttg aagcagctaa agctgcgcgt gagaaattgt
     8941 aagattggat ttctctccat acagtggttg ttcaaaaaga aatcaactag aaaaggttat
     9001 tacatatgtc acgccaaaca ccgtcactct catttgaagt gttccctcca aacccagccg
     9061 tgggtaatgg taacattatt tcagccttgc aggatatgca ggagttggct ccccatttta
     9121 tcagtgtaac tgccagcaat aataaattta atatcaagga aacgacggtt cgtttggctg
     9181 actttatcca aaatgatttg gcgattccga ccattgccca cttgccagct atttatctaa
     9241 ctaaggacaa ggttgctgaa actattgctg acttggacaa agttggggtg cagaaaatct
     9301 tggctcttcg tggggatatt attccagacg tggaaccaca aaaggatttc cgctatgcaa
     9361 ccgacttgat tgagtttatc aaggaacaaa cccctcactt tgatattatt ggagcttgct
     9421 atccagaagg gcatccagat tcgccaaatc agatttcaga tattcaaaat cttaagaaga
     9481 aagtggatgc aggctgttcg agcctcgtaa ctcagctctt ctttgacaat gagcgcttct
     9541 atgattttca ggacaagtgc atcttggctg ggattgatgt tcccattcat gcaggaatta
     9601 tgccaattct gaatcgaaat caggctctcc gactcttgaa gacttgtgag aatatccatc
     9661 ttccacgcaa atttaaagcc atcttagaca agtatgagca tgaccctgag tcgctcagag
     9721 cagcaggact tgcctatgca gtggaccaaa tcgtggactt ggtaactcag gatgttgccg
     9781 gtgtgcatct ctatacgatg aataatgctg atacagcaaa atacatccat caagcaaccc
     9841 atgccttgtt taatcaccag tctctaggat aataaaagca aaccattctt ctcaggtgag
     9901 gggaatggtt cctttttaat ggtaaagacc tcacttttta agaaaaatat gataaaataa
     9961 attctgtacg tacttgatac aaagatgaag gtattaaata atacaatgca tttaaactgt
    10021 aagatttaac gacacgagtg agtcaaatcg atgttatttg acgagagagt tagtaaagca
    10081 tttagctaat cgcccgatag cgattagcgt gaaagcttta gatactttag tattaaacct
    10141 ttctaatgat gtatcttgaa aactgaactt gcctacaact ctgtggaaaa agataaatct
    10201 ccctaggagc agtcgctccg tcgttcgatt tcctattttc ctttgagttg cttgacggct
    10261 tggtatcttg atgacttgaa ttttggtctc atttcttagg aaaaaagata agcttcctag
    10321 cactcgtcga gtgcgacgtc accttcctat ttttctacag aaatgttcgg caagccgaac
    10381 cgtccaaaat atcttgtgta attgaacacg gccgaaaagc tgtgtaaaaa agataaactg
    10441 tcttgtcttc atcgaagact tcgtcagttt cctattttta ctttgctttt gacgtccttg
    10501 gtatcttgat ctttgtaggc aaggcgtata atttcatcaa tccaaagggg attaaaatgg
    10561 caaaacaagt gtttcaaacg acttttgcgg gtcgtgagtt aattgtagaa actggtcagg
    10621 ttgctaagca agcaaatggc tctgttgtcg tacgttacgg tgagtcaact gtcttgactg
    10681 ctgccgttat gtctaagaaa atggcaactg gggatttctt cccactccaa gtcaactacg
    10741 aagaaaaaat gtatgcggct gggaagtttc ctggtggctt tatgaaacgt gaaggacgtc
    10801 cttcaacaga tgcgaccttg acagcgcgtt tgattgaccg tccgattcgt cctatgtttg
    10861 cggaaggttt ccgtaatgaa gtccaagtca tcaatacagt gctttcttat gatgaaaatg
    10921 catctgcacc aatggctgct atgtttggtt catctttggc actgtctatt tcagatattc
    10981 catttgacgg accaattgct ggggtacaag tgggatatgt agatggccaa atcatcatca
    11041 acccaagtca agaacaagca gagcaatctc ttcttgaatt gacagtagct ggaaccaagc
    11101 acgctatcaa catggtagag tctggtgcca aagaattgtc agaagaaatc atgttggaag
    11161 cgcttcttaa agggcacgaa gctgtcaaag aattgattgc cttccaagaa gaaatcgttg
    11221 ctgctgtcgg taaagaaaaa gcagaagtgg aattgcttca cgtggatgct gaattgcaag
    11281 ctgaaatcat tgcagcctac aacagtgacc tccaaaaggc agttcaagta gaagagaaat
    11341 tggcccgtga agctgcaact caagcagtga aagaccaagt gactgccgtt tacgaagaaa
    11401 aatatgcgaa ccacgaagaa tttgaccgta ttatgcgtga tgtggctgaa atcttggaac
    11461 aaatggaaca cgcagaagtg cgacgtttaa ttacagaaga caaggtgcgt cctgatggtc
    11521 gtaaggtcga tgaaatccgt cctttggatg cggttgttga cttccttcct cgtgtacatg
    11581 gttcaggtct ctttactcgt gggcaaactc aagctctttc agtcttgacc ttggctccga
    11641 tgggagaaac tcaaatcatt gatggtttgg atccagagta caagaaacgc tttatgcacc
    11701 actataactt ccctcaatat tctgtagggg aaacaggtcg ttacggtgcg ccaggtcgtc
    11761 gtgaaatcgg tcacggtgct cttggtgagc gtgctcttgc tcaagtcttg ccaagcttgg
    11821 aagaattccc atacgctatc cgtctagtag cagaagtttt ggaatcaaac ggttcttcat
    11881 ctcaagcttc tatctgtgcg ggaactcttg cccttatggc tggtggtgtg ccaatcaagg
    11941 cgccagtagc tggtattgct atgggactta tctcagatgg aaataactac acagtattga
    12001 cagatatcca aggtttggaa gatcactttg gagatatgga cttcaaggtt gcaggtactc
    12061 gtgatgggat tacagccctt caaatggata tcaagattca agggattact gcagaaatct
    12121 tgacggaggc tcttgctcaa gccaagaaag cgcgttttga aatccttgat gtcattgaag
    12181 caaccattcc agaagttcgt ccagaattgg ctccaactgc tccgaaaatt gatacgatca
    12241 agattgatgt ggacaagatt aagattgtca tcggtaaggg tggagaaacc atcgacaaga
    12301 ttatcgctga aacaggtgtt aagattgata tagacgaaga aggaaatgtg tctatctact
    12361 ctagtgacca agatgctatt aaccgtgcca aagaaattat tgctggtttg gttcgtgaag
    12421 ccaaagtgga tgaagtttac cgtgctaaag tcgttcgtat cgagaaattt ggtgcctttg
    12481 ttaacctctt tgataagaca gatgcccttg ttcatatctc tgagatggct tggactcgta
    12541 ccaatcgtgt agaggatttg gtagaaatcg gggatgaagt tgatgttaag gttatcaaga
    12601 ttgatgaaaa aggccgtatc gatgcctcta tgaaggctct tctacctcgt ccgccaaaac
    12661 ctgagcatga tgaaaaaggt gaaaagtctg agcgccctca ccgcccacgt catcacaagg
    12721 atcacaaacc taagaaagaa tttacagaaa caccaaaaga ttcagagtaa gaaaaggaga
    12781 aatgtatggg gtggtggcgc gaaaccattg atatcgtaaa agaaaatgat ccagcggccc
    12841 gcaccacttt ggaggttttg ctgacttatc caggtgtcaa ggccttggcg gcccaccgtc
    12901 tctcgcattt tctctggaag cacggcttca aactcttagc tcgtatgtac agtcagtttt
    12961 ggcgcttttg gactcagatt gagattcatc caggagccca gattgattca ggtgtcttta
    13021 ttgaccatgg ttctggtctg gtgattggag agacagcgat tgttgaaaaa ggcgttcttc
    13081 tctatcacgg agtgactctt gggggaacag ggaaagactg tggcaaacgc catccgactg
    13141 tacgaaaggg agccctcata tcagcccatg cccaagttat cggacctgtg gaaattggtg
    13201 aaaatgccaa ggtcggtgct gcagcagttg tcgtagcaga tgtacctagt gatgtgacgg
    13261 ttgtcggtat tccggccaag attgtccgtc ttcatggtaa gaaagatgag cctgtcattc
    13321 acgaagtcga agaaaaacga gagtattatg tcaataaact cgagcaggct aaagatgcca
    13381 gtcacagatc gtctggtttg tagaggatac ctatatgatt caagtaagaa acaagttaag
    13441 ccaagaggag ctatctgagg cgaaaaaagt aattaactgt tgccaaaact atgacggtac
    13501 ctatcgcgat ccctatctct ctaacatgct taattttgac ccaaacatgc ccgccttttt
    13561 cctttattat gaaaaaggcg aacttgttgg tttattaact gtctatgcag atgaccaaga
    13621 tgtagaagtg acgatactgg ttcatccagg tcatcgccgt caggggattg cgcgtgcatt
    13681 gtttactagt tttgagagag aaacagcttc tttccccatt cgatcagtca cttttcagac
    13741 agaacgtatt tttttagaga atcatcctga ctttgccagt aactggggac taatcgagga
    13801 tgaagagaca gaaacttggt taggtaagga tagaagacct tatccgttag caaatgtttc
    13861 ccatcttgaa gttttgttag cagatagttc gtatcaggat caaattagtc aattaaaatt
    13921 tcaggcattt tcagaggaac atgaatcgag agaagttgtg gatagatatg tcgctgaagc
    13981 tctgaaggat ccagaaagtc gcttatatat tttgttaaaa gacggtcagg ttattgggac
    14041 ttgcacggtt gatttatcga gcgatacgaa ttacttctac ggtttagcaa tatcagaacc
    14101 tgaacgtgga aaaggctatg gaagctactt agcaaaatcc cttgtcaacc aactaattga
    14161 gcaaaatgat aaggaatttc agattgcagt ggaagatagc aatgtaggtg ccaaacgttt
    14221 gtatgaaaaa attggctttg tcaaacagac tcaggtggtt tatctgaatg agaaaggagc
    14281 aagggattcc gaagtgtaga gatattcgga ctgaaattta cttgaacttt tagtgatgaa
    14341 actaattgtt cttggatttc agctttcctg attatgattt atgattaaaa tctatgacac
    14401 catgtctcgt gatttgcgag aatttgtccc gattgaggac ggcaagatca agatgtatgt
    14461 ttgtgggcca acggtgtaca actatatcca cgtgggaaac gcccgttcga cggtagcttt
    14521 tgatacgatt cgtcgctatt ttgagtaccg tgggtataag gttgcctata tttccaattt
    14581 tacagatgtg gatgataaga ttatcaaccg tgccagggaa gaaggtatca cgcctcagga
    14641 ggttgcggat aagtacatcg ctgcctttcg tgaggatgtg acggccttag gcgtgaaacc
    14701 tgcgactcgc catccgcgtg tagtggagtt tatggcagac atcatccgtt ttgtggaaga
    14761 cttgatcgag aaaggctttg cctatgagag tcaaggggat gtctatttcc gtgtagaaaa
    14821 atcccacaac tatgccaaat tggctaataa aaccttggaa gatttggatc taggtgcttc
    14881 aggtcgtacc gatgaagaaa cggttcgtaa ggaaaatcct gtagattttg ctctatggaa
    14941 atcttccaaa ccaggtgaga tttcttggga tagtccttgg ggacctggac gtccgggttg
    15001 gcacattgag tgttcagtca tgtcgacaga gattttaggt gataccattg atatccacgg
    15061 tggtggagct gacctagaat ttccgcacca caccaatgaa attgcccaat ctgaagctaa
    15121 aacaggcaag gcttttgcta actactggat gcacaatggc tttgtcaata tcgacaatgt
    15181 caaaatgtct aagtccttgg gtaacttcat tacggtacac gatgccctta aaactcttga
    15241 tgggcaagta cttcgtttct tctttgcgac ccagcactac cgtaagccta tcaacttcac
    15301 ggaaaaggca gttcgcgatg ccgagaccaa tctcaagtat ctgaagaata cttacgaaca
    15361 accatttaca ggaaacgtgg atgcccaaga gttacaaaac tttaaagata agtttgtagc
    15421 agctatggat gaagatttta atgctgccaa cggtatcaca gttgtctttg aaatgaccaa
    15481 atggatcaac tcagggaact atgatgcaag tgtcaagcaa gctcttgcag atatgttaga
    15541 aatttttgga attgtctttg ttgaggaagt tttggatgca gagattgaag acttgattca
    15601 aaaacgccaa gaggcgcgtg ccaatcgaga ctttgagaca gcagaccaaa tccgtgacca
    15661 actggctgct caaggcatta aactattgga tacaaaagat ggagtgaggt ggacacgtga
    15721 ttgatgtcaa tctcattaac gggattgcgc tagcctttga gggagatgcg gtgtattcta
    15781 tgtatattcg ccgccacctc atcctcaaag gtatgaccaa acccaataaa ctccatcaag
    15841 aagcaaccaa gtatgtgtca gccaaggctc aggctcgcct gattgctctc atgttggagg
    15901 agcaggtcct aacggaaaaa gaagaagaaa tctacaaacg tggccgcaat accaatagcc
    15961 acacaaaggc taaaaatgca gatgtcgtga cttatcgtat gtccacggga tttgaagcgg
    16021 ttatgggcta tctccatatg actgagaatc tggaacgtct tgagagtttg gtttcatggt
    16081 gcatccaaaa agtggagggc tagaacatga gggaaaaaga actacaagac tggtttcctg
    16141 aggctcggat ttcagaccaa ccagtagaga aagagggcta tctcacgctc cctttagctt
    16201 ctcagcagtg gattttgctg gaggaagctg ggctcagcga gcgtgaaaag cagttggttg
    16261 cccttttgac ccagcaggag caggctcgtt cgctaaaccc ttggtattcc tatctggttg
    16321 aaggcaaggg acaggcaccg caagttttta aaaagattca gttggtttat tgccatcttt
    16381 cttattttca gcaggaaaat ctgacttctt ggctagatat gatgcggact ctttttccga
    16441 attgtcagac agtgctacag gtcggagctc aggattatgt tttcgtgctt caacaagaca
    16501 aatacacttc tgtaagagat attttaagtg atacgattga agcggttgag tatgattttg
    16561 gacttcgtct ttctatcatg ttgggtcagg tttggtctca gacaggacat caagccctat
    16621 cagacttaat caaagctgag cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag
    16681 gtgttcatac tttttctcag ctctatcttt ggagtatggg agaaagactc gtggacttga
    16741 agccaattaa agaatgtcta caccagatga ttttggatca agatcagatt caggaaatca
    16801 ttctctctct ttgggaaaat agtgctgttc tcactaaaac agcccagcaa ctctatctgc
    16861 accgcaattc tctccaatac aagattgata aatgggaaga gttgacaggg cttcagttga
    16921 aagagttgac cgacctgacc ttgtgttatc aattgatttt aggttctttg tcaactatag
    16981 ttggtttgta aagaagttaa tatttggaga agaggattgc catcttctcc atttttatgt
    17041 gcagagttat agtggcttga tgctgggaaa gtacactgtg actgataata ctcaatgaaa
    17101 atcaaagtac aaactaggaa gctagccgca ggctgtactt gagtacgtca aggtgaagct
    17161 gacgtggttt gaagagattt tcgaagagta taaaacattc ctagaagttg ctttgatttc
    17221 cctaatctat ttatgcaaat tttatgttat tttactataa cagttgttgc taagccaaat
    17281 aatagtgggg aagttcattt agacgtaagc attgaagata atcagggagg tagtgggcat
    17341 aatttcagtt ctgtttcaag tagctcacaa acagctaaat atgaagaaac tggttataat
    17401 aacaattcat cattatatac aacgattgat aaaacgtctg atgcaacagc tcttttgaaa
    17461 ttaaagttga ataatgttga taatcaacct gctactgaag ttcctagttc aggaattact
    17521 gtaaaattaa atgctaaaga taatgctgga aactggacaa gtgcttcgaa taaaaaagaa
    17581 ataacagtaa aaattgtttc tgctaaaccg acatatccag acaaaatctt agtgaaaaat
    17641 cctgataata taaaagatac agaaaaaaat gccattattg aaaaattgaa agaggcaaat
    17701 aaaaatcatc cagcaggagc tccaaccttt gctaaaggtg aaggagagca tgcaaatgat
    17761 attgtagcaa cttattcaga tggtacaact tattatgcac cgttaaatga tgtgacaaaa
    17821 tatgcgaggt agtggctgta ccactcactt attcacctcc ccgtgatttg tagtagtgat
    17881 aggctttctc actattatta taaaacaaaa taaagatcac aacacttttt cattctgtgt
    17941 tgtgccttga gtgaaacgaa aggaatgaat tataaatatg aaaagtatag tcac
//
LOCUS       DAVMCN010000035        17274 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVMCN010000035 DAVMCN010000000
VERSION     DAVMCN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.035"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..804)
                     /locus_tag="VYP85_001407"
     CDS             complement(<1..804)
                     /locus_tag="VYP85_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEV1881904.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFD"
     gene            complement(791..1561)
                     /locus_tag="VYP85_001408"
     CDS             complement(791..1561)
                     /locus_tag="VYP85_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1881905.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMVLEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(1587..2441)
                     /locus_tag="VYP85_001409"
     CDS             complement(1587..2441)
                     /locus_tag="VYP85_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV1881906.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(2598..3002)
                     /locus_tag="VYP85_001410"
     CDS             complement(2598..3002)
                     /locus_tag="VYP85_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1881907.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(3072..4553)
                     /locus_tag="VYP85_001411"
     CDS             complement(3072..4553)
                     /locus_tag="VYP85_001411"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1881908.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRIPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            complement(4572..5750)
                     /locus_tag="VYP85_001412"
     CDS             complement(4572..5750)
                     /locus_tag="VYP85_001412"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1881909.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            5914..6921
                     /gene="galR"
                     /locus_tag="VYP85_001413"
     CDS             5914..6921
                     /gene="galR"
                     /locus_tag="VYP85_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1881910.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLNQ
                     E"
     gene            complement(6967..8004)
                     /locus_tag="VYP85_001414"
     CDS             complement(6967..8004)
                     /locus_tag="VYP85_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1881911.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(8005..8358)
                     /locus_tag="VYP85_001415"
     CDS             complement(8005..8358)
                     /locus_tag="VYP85_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1881912.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(8602..9492)
                     /locus_tag="VYP85_001416"
     CDS             complement(8602..9492)
                     /locus_tag="VYP85_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1881913.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            9625..10161
                     /locus_tag="VYP85_001417"
     CDS             9625..10161
                     /locus_tag="VYP85_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1881914.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            complement(10327..11133)
                     /locus_tag="VYP85_001418"
     CDS             complement(10327..11133)
                     /locus_tag="VYP85_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1881915.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(11478..12998)
                     /locus_tag="VYP85_001419"
     CDS             complement(11478..12998)
                     /locus_tag="VYP85_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1881916.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(12991..13719)
                     /locus_tag="VYP85_001420"
     CDS             complement(12991..13719)
                     /locus_tag="VYP85_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881917.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(13734..14497)
                     /locus_tag="VYP85_001421"
                     /pseudo
     CDS             complement(13734..14497)
                     /locus_tag="VYP85_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
     gene            complement(14501..14944)
                     /locus_tag="VYP85_001422"
     CDS             complement(14501..14944)
                     /locus_tag="VYP85_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1881918.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(15626..15922)
                     /locus_tag="VYP85_001423"
     CDS             complement(15626..15922)
                     /locus_tag="VYP85_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1881919.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AARLSGLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            complement(15944..17008)
                     /gene="pepA"
                     /locus_tag="VYP85_001424"
     CDS             complement(15944..17008)
                     /gene="pepA"
                     /locus_tag="VYP85_001424"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1881920.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
BASE COUNT         5179 a         4049 c         2908 g         5138 t
ORIGIN      
        1 atcaaatgtt tctcgtaaat tattcttagc cttataccaa ccttgtccat cagtaatcca
       61 cataaactca acattaggaa tagctttaat ttcttcagca atcattttgt aagatctagc
      121 cgtctcattt aattttgaac cacttcctga ataaaaatta acctcaatca gataaagcac
      181 ttgttcattt tttatgacaa aatcaaaacg tttcacagta ttcccatcat tcgtaatagc
      241 agataaatcg acagaaaaaa tttcctctat ttcattttgt tcaatctctt taaataaatt
      301 ctctcctaaa atataccctt cagcttcaag ataactttga acaatatttt ccatcgcatc
      361 tccagtccga tttttgcgcc cattagtatc cataccaacc tcaacacctg taacgtagtc
      421 aactaaattt gatactaaat gattttgcaa taaatcaaat atacctgatt tttccaaaaa
      481 catagtatat tcttcaatac tatagtttcg tttactaaaa tcaaaataga aatcttttat
      541 cggatcctta acaataatcg tatctctcaa acgtttagca ataagtagag gcacaacttt
      601 caaaatttct ggataatttt gatataagtc taaaaaatcc tcttgtatat ttttactacc
      661 aataagacta ttcataatat ttagagcaac ttttatacta gatacatttt tataaacctt
      721 gggaaaatct gtataataag tccagtcagc tactgtgtcg gtcatcgttg acaaccactc
      781 atcaaaattt ctagtttgtt tcattttctg cctccaacct cttccttgca atttttaaat
      841 attctttttc agcatcgata cctataaatc ttctacctaa ccgcttcgca acaacacccg
      901 tagtgccact accaacaaat gggtctagaa tatagtcacc ctctttagta gaggctaaaa
      961 taatgcgttc taacaaatac tctggttttt gagttggatg tttcccagcc catttttcaa
     1021 ctttctttgt taaagaaccc gtccagacat ctttcatttg ttttccatca ttcaattctt
     1081 tcattaaatc ataattgtag taatgacgag cttttttatc attttttctg gcccataaaa
     1141 tggtttcagt agaatgggta aaataacgac aagataaatt gggggcaggg tttgttttct
     1201 gccaagtaat attattcaga attttaaaac cttcttgttc taataccatt ccaactgagt
     1261 atatgttgtg caaactacct gaaatccata ccgtcccatt aggcttcaga acttcttttg
     1321 ctaggcgaat ccatttacga ttaaactcat gtttttcttc gaatgaagaa attttatccc
     1381 aatctccttt atcaacagaa acaacttgtc ccccagaatt agatattcca ccattactta
     1441 aaaaataagg tggatcagca aaaatcatat ccatactttc tggtttcatt tttgataaga
     1501 acttgaacgt atctgaatga acaagaatca tcttattttt attgtagtat ggttttgtca
     1561 taagaacacc tccatactta tattcgttat ttttcataat ttgtgactat aatttcagaa
     1621 atttttcctc gacttgaaga ttttgctcca ttagttcggg tagcttcaac ataatgtata
     1681 ttaaaatcct tatacaactc ctctactaaa gcactagaag aatttgataa cataacataa
     1741 gctcctgtat cactcaatct cttaaaggca tctcttaatc ttacttgatc tgcaaaagag
     1801 aatccctcat gagtataaga cgtaaatgca ctcgtctcag acaatggaat atatggaggg
     1861 tcaaaataca caaaatctcc tgttcgaaca tctacaattg ccttttcaaa atctcccact
     1921 ttaatttcta gttgattgtt atttatataa actgaaatag cagatatcaa ttcctcatca
     1981 acaattttag gattcttata acgtccatat ggaacattaa attgattctt agaattcaca
     2041 cgatatagac cattaaagtt cactctcaac atatatagaa tacgtgcagc tctttgtact
     2101 tcggacatca tatctattct ttcatcacga tctgcagaac gtaaatctaa ataatattct
     2161 tttgaattat attcctgatg aactttcaaa atttcaatca attcttgagg attgtcctta
     2221 atttgttgat agcaatttat tagttcagcg ttaaaatcat taataactgc atctttagga
     2281 gccaaatcaa aaaataaagc tccacctcca acaaaaggtt cgaaatacct gttataggtt
     2341 ttaggcatta attctctaat aacaggcaat aattgtcttt taccacctgt ccatttcgtg
     2401 aacggttgta aagtaacttt ctttatttct tttatcttca tgcttttaat tataccatag
     2461 aaattaaaac acaactcttg tattttctac cacattacta aattttctat tttagaatta
     2521 aatcatatca atatcaaaaa atgagtaagg caaatcttat aaattccaaa attcacctca
     2581 ctctattaaa ttactcttta tatccttacc tgtctttctt ctgaccgctg gcctgtgaca
     2641 aacatggtaa aggttgcttt acagacattt ctgccctctt gattggtgat atccacatcc
     2701 atcacacagg ttgtacggcc ttgatggaca cattctcctt taatggtcaa tacatcgtcg
     2761 agttttcctg ccttaaggta gttgatagag gattggagtg tcaccccatc aagtcccagc
     2821 gagataacca ccaaaccact gatttggtca catagcgtga atagatagcc accatgggca
     2881 ttgccatagt agttgagcga cgagttcact actttggtcg tcaccacaac gtgaccatct
     2941 ctcatttttt caatttcgta attttcaaag gcagatatag cgtcaaaatg aaagtctttc
     3001 atcgtttcct cctgatattt caaacgacac tatgatacta ctttttatag gactgtgcaa
     3061 ggagaaagct cctagtctag tgaaattccg acatgttcca caaagcgcat aaaggctgtc
     3121 tgcccttgtt ctgtctgctt gtagactcct gcatcctcaa gtacacgcac aaagatagca
     3181 cccacagagt ccttgacgat tgcaagggct ttttctttat ccgttaggtc tggatgttgg
     3241 gatttgagtt ggtctgccca ctcctgatga taatcggcaa ctgtaacagc ttctcctaca
     3301 agatagctag cgacttgctc cacttcttct ttcagacgtg gtggcaagat tgccaagccc
     3361 atgacctcaa tcaagccgat attttccttc ttgatatgtt ggacatcctt gtggggatga
     3421 tagatgccat caggatgctc tgctgaagtc tgattgtctc gcaagaccaa gtccaactca
     3481 aactgtccat cacgcttacg cgctattggt gtgatggtgt gatgcggtgt cccgtctgtc
     3541 tctgccaaaa tctgcacact agaatctgaa tactgacgcc attcctggaa aatcttatca
     3601 gctaagttaa tcaaatcctc tttggaatcc gaagtcaagc gtaggacaga cattggccac
     3661 ttgataattc cagccttgac ctgctcaaaa ccagcaaatc ggaaggtctt ttgcaaggga
     3721 gccaattcca taggaaatac gtgacggcct ccctgataat gatcatgagt tagaatagag
     3781 ccccccacaa tcggcaggtc ggcattagat ccagcaaaat atcctggaaa ctgctctacg
     3841 atagccaaca gacgttcaaa actctgacga ctaatggcca tgggacgatg ctgaccatct
     3901 aaaaagatac aatgctcatt aaagtaagca tagggcgaat actggaaccc ccattcctga
     3961 ccaaccattt caaaacggat aatccggtgg ttgctgcgag ctgggtggtt gacccgacca
     4021 tggtaaccct cattctctaa acaaagttga cactgaggat aattactagc ttgcaccaac
     4081 ttggctaccg caatctcttt cggatccttt tcaggcttag agagattgat ggtaatttca
     4141 agttctccat aatcagatgg aatacgataa gcgatatttt tagcaatggc cttgagtttg
     4201 atgtagtcat ttttccgact gagttgataa aaatcctcta tcgcttgctc aggagagtag
     4261 gcataggctt cccagaagtc acgattgacc tgactcggac aaggagtcac caagtccatc
     4321 agttcagtac caaggatttc acgcgcagtc tgactatcct caatcgtctc taatcgaacg
     4381 gcttcctcaa ctagctggtc cttgaggtca atcaatttat ccagattggt ctcaacttcc
     4441 aaaacacctt ctcccactcg tgccaaaaca cgattggtca ggtagattcg atccatttcc
     4501 tcaaatgaac tttcagaaat gacatgtgtt acaaatttat ctactaaggt cactatagag
     4561 cctccttttg actagtcaag gacgcgagtg ccacctgcaa cttcagcgat atagaagctt
     4621 ggagcgtatc caactacttc ctcgtagtgt ttgcctacag cttccttaaa ggcctcaaca
     4681 gtatcttttt gaaccaaggc aatggcacag ccaccaaaac cagcccctgt catacgagca
     4741 ccgagaactc cttcttgtgc ccaagctgtg tgaacaagag tatccaattc caaaccagtt
     4801 acttcataat catgctccag agaaacgtgt gacgcattca tcaaacgacc aaatgtttcc
     4861 aaatcacctg cttgaagggc tgcttgagct ttaagggtac gttggttttc aagcacagca
     4921 tggcgagcac gtttcaaacg attttcatct ttaatcagat agctatattg gtcaacggcc
     4981 cactcgtcca attcacccag ggtctgaata tccaaggcaa cttgcaattc ttccactgct
     5041 ttttcacact cagcacgacg ttcattgtat ttagagtccg ccaattcacg gcgtttgttg
     5101 gtgttcatga taacaacgac attgtccttc aaatcaagtg gcaccaagtc gtattctaaa
     5161 gtattggtat ctaagtaaat agcacgttgg tcagccccca taccaatagc aaattggtcc
     5221 ataatgccag aatttactcc gataaagtta ttttctgttt gttttccgat tttaaccaaa
     5281 tcgagacgct ctaattttaa atcaaagaga tgctctgcca ctacccctgt caagagttca
     5341 agggatgctg aagaagacaa accagcacca tttgggatat tcccataaac ataaaaatca
     5401 aaacctttgt caatcacgtg cccagcttct tgcaagaaat gaaggacacc ttttggataa
     5461 ttggtccagt tgtgctcttt ttcaaacttg aggtcagcga gaggcacttc gataatgccc
     5521 ttgtcctcaa agttagctga gtagaaacgc aagacttggt catcacgctt gcgagctgca
     5581 ccataagttc ctaaggaaat agcagctgga aaaacgtgcc caccgttgta gtctgtgtgt
     5641 tcaccaatca aattaatacg gcctggtgaa aagaaagttt ggtctgcttc ttgaccaaaa
     5701 acagcaagaa agtctttgcg aagagtttca gcagtaagat gttgtgtcat atgatttctc
     5761 ctttgactgt ccgttaagcc accttaacgt gtaatcgttt tcttctattg tatccaaggg
     5821 atttcccaag gtcaatcctt tttactaaaa ttttactaaa ctatcagtaa aaagcagaaa
     5881 aatatgatat actaacctaa tcaaggagga tttatggcta ccttaaaaga cattgcacag
     5941 ctagcctctg tctctatcgc gaccgtatcc cgtgtcctca accgcgacca gagcctatct
     6001 gttacagaag aaaccagaca ccgtatttta accgttgctg aagagctggg ctacaccaag
     6061 cacctcaaga caggcgagtc ccataaaccc aagcaaaaga ttgccattat tcaatgggtc
     6121 agcgaacaag gggagctaga cgacctctac tactaccaga ttcgcctagg aatagaaaaa
     6181 agagcccaag agttggacta cgatatcttg cgctatttta atgaccaccc ttttacccta
     6241 agcgaggaag tgattgggat tctctgcatc ggaaagttta gtcgagctca gatttctgcc
     6301 tttgaagaat accaaaagcc tcttgtattt ctagacagcg atacactttc cctgggacat
     6361 acctgtatta tcacggattt ttacactgct atgaaacagg ttgtcgatta tttcctcagt
     6421 caagggatgg accgcatcgg gattctaaca gggcttgagg aaacaacaga ccaagaagaa
     6481 atcattcagg acaagcgtct agaaaacttc aaaaactaca gtcaagcgag gggaatctat
     6541 catgatgaac tggtctttca aggaagattt actgcccagt ctggctatga cttaatgaag
     6601 gaggccattc agagcttggg agaccaactt ccgccagcat ttttcgcagc cagcgatagt
     6661 ttagctatcg gtgccctccg tgccctccaa gaagctggaa tcagcctgcc agatcgcgtc
     6721 agcctcattt cattcaacga caccagtctg accaaacagg tctatcctcc cctctctagt
     6781 attacagttt atactgaaga aatggggcga gcaggtatgg atattcttaa caaagaagta
     6841 ctccacggtc ggaaaatacc tagcctgacc atgttgggaa ccaaactgac gttaagagaa
     6901 agtaccctaa atcaagaata ggataacata aaaaacgaat agagttctaa aactcctatt
     6961 cgttttttat tcgattacaa tcatagactt aattgtctta cgttcatcca tatctttata
     7021 ggcttggtcg atatcttcca gtttataact tgaagtaaag acgcgacctg gattgatatc
     7081 accatcaagg acggctttta gtaaaaattg cttatcgtat gttgtagcag aagctgcccc
     7141 acctgctaca gagatatttt gcataaatgt cgaaccaaga gcacgattat tatagtgtgg
     7201 gactcctaca aagcccatac gccctccatt atgaagaaca cctagcgcct gttctatagc
     7261 agcctccgta ccaacacatt caagtgctgc gtctgctcct ccgccgagga tttcacgcac
     7321 cttggtaatt ccttcttgac cacgttctgc aacaacagct gtcgcacctg actccatagc
     7381 catcttttga cggtcttcat gacggctcat aaggataatt tgtgatgctc cacgcatctt
     7441 agccgcgatg acagcacatt gaccaacagc cccatcaccg ataacaacaa ccttgtcccc
     7501 tttttgaaca tttgcaacac gcgctgcatg atagcctgtc ggcatgacat ctgcaagagt
     7561 caaaagggac ttgagcatcc cttctgtata atcagaaggt tgaccaggga ttttaaccag
     7621 cgcccagttt gcatagtgga agcgaatata ttctgcctga aaatcacccc ccaaattatt
     7681 accaatatga ttgtcgcaag aaccgtcaaa tccagcaaga caggcatcac actcaccaca
     7741 tccatgtgta aaagggacaa tcacaaaatc acctggtttc accgtcgtaa tggcttcccc
     7801 agcttcttca acaatcccaa tcgcttcgtg tccactattt ttatgtccag ctttcgtttc
     7861 tggattacgg tacctccata aatctgaacc acaaacgcac gcacgaacca cacgaataat
     7921 cacatcatcc gcttctatta tttgcggacg ttcaatgcta gcaagtccaa cctgacctgc
     7981 ctttgtatat actgctgatt tcatttaaaa ttttccttcc ttataaagtt taattttgag
     8041 atttaaacga tttaaagctg tctgtagctg agacaagcgc tcctctaatt tttgcttttc
     8101 ctcttctaaa ataccaagcc tctcctctct cgtttcatct cccttttggt agagcgacat
     8161 atagtcaact aaactatcta cagagacacc cgccgaacga aaacacttaa taaattccag
     8221 cgcttcgata tcctgatctt gaaaatcacg aatcccagta gcagtacgag taatcggtgg
     8281 cacaagacca acccgttcat aataccgaat cgtatccgct gaaattccca acaaatcact
     8341 ggcagattta atattcacac gctaacctcc tctcatttca ttcactgaat tcacgctatt
     8401 ctaactcact tatcttatta tataactttg agttgactcc aagtcaagca ttttgtatct
     8461 aatcgaaaaa tttttatcat taacaatcat atatctggag tttatacaat gctcttctct
     8521 taccaatttt tgaaatattt aaataataaa gaaattactc tattccaaat aagatagtac
     8581 ccaagtattt ttcacttttt tctaatgttg atgctcataa ctccgttcca agtcacacac
     8641 ctttcgctta tgggtttggt gagtttctag gtcagcatca atttcaatgg taatattttg
     8701 aaaaccacaa tcttttagga aaattcgaat agactcttta caagtttcca tatgttccat
     8761 ttcttttaga caaacatgta caatggcatt tttttccaaa gcatccatag tccagagatt
     8821 aagctgatta aggctggcca cattgtccaa tcgctccagg ccactcttta cttgcttgat
     8881 atcaagacct tctggcacag catccaagaa aatcttgagt gtagaccaaa aacgtggaag
     8941 ggcttttgaa agaataaaga aagaaatgac aagggacaaa agaggatcta ggatatacca
     9001 gtccgtaaat cgaagaacaa tcgccatcag gataacagct acccacccta gcgtatcttc
     9061 cagaaaatgc aaactcagaa tagactcatt ctttgtcttt cccttaccaa ccaccagact
     9121 cgctaacaga ttgatagtaa tcgcaataat tcctaaccag agaatcccct catcattgac
     9181 tggttgcgga tgcaaaatct tcgtgacatt ttccaaaatg actagaacag agcccgttac
     9241 gagaatcaca gctgttacca aggctcctag caggctaaac cgcttatagc ccaaggtgta
     9301 ctgattgtct tcttcacgat tggagattgt ttctagaaaa gctgatattc caattgcaat
     9361 cgcatctccc aagtcatgca cagagtcagc aagaacagcg ctagaaccaa atactccacc
     9421 tgcaataaac tcaacaatgg cataagtcaa atttaagaaa aaagccaccc aaacagcata
     9481 ttttgccttc atatttctca ttcctttgtt ataatagatt tatgaacacc ttgttcatta
     9541 tcattatcca ctaaaactca aagaaaggat agaagcaaaa cgtcagcttt attcagttct
     9601 gaacaatttg ccttaagtgt ccatatgact aacattgacc gccgtatcag caaaaccaaa
     9661 aaagccatct atcaagcttt tatacaactt ttgaatgcta agggctacga ggccactact
     9721 gttcaggata tcattgatct cgcagatgtg ggaagatcca ccttttactg tcactatgaa
     9781 agtaaggagc ttcttctgga ccagctctgc cgctacctct tccatcatct ttttgaaaga
     9841 gagcaagcca tttcaaccga ggactacctc gcccacctct ttctccattt tcataaaaac
     9901 caagaccata tcaccagtct gctattttcc aaaaatgact acttcctccg tcaactccat
     9961 aaagagctag aacaccatgt ctattccgtg ctagctgata atttaaaaga agcccaccct
    10021 aatatgccta cttcttacct ccaacacttg gtcgtgtcca actttatcga gacattgacc
    10081 tggtggctca aaaaaggtca agatttcaca ggccaggaag ttgtccaatt ttatctagac
    10141 cttctcattc ctaaaaattg aatatagagt aaagctcagt tgtcttattt ctaggttact
    10201 gagtttttta tcttttcaac aacaaaagag gacccgccga tcctcttttt catactataa
    10261 atccttgatt atcaactata tctgttttaa tcgaaatctc aaaacagcac tttcaaacat
    10321 cttttcctag ttaagtaaat cagtattctg cttagctgcc ttgctccatt gataccaacc
    10381 aactagactg ttaatgagat aaattagata tttcccttga atttgcaggc tttctcccca
    10441 ccagagatag attgaaaaaa cattggtagc cgcccagaat atccactgtt cacggtaaac
    10501 agctgtcatg aggatttgcc ctaccccatt ggttgcatct gtgattgaat cacgataggg
    10561 acgattggca ccaatagact gataaatgaa gccaaaggcc aaccaccaaa gcacactaat
    10621 ggaaagatac tttgtccagc ccttgccgtc cagtttacgc gcgacaaact cctgcttttc
    10681 cttcttaaac tgtgcctgat aaatccaaac tagaagtcca attggctgca tgactgtgaa
    10741 gtaaagtgtc gtcagcacct caccataaaa gcctttctgt agggccaaaa taaggtaaat
    10801 aacagagtta atcaagccaa aaagataatt acttgctcga ccttccgata caaagattac
    10861 acagataatc cctgtcaagc tacaaatcat cccaatccag tcaacaatac gatgttcgta
    10921 aaccaactcc agccagagag gaaaacttcc taaaaccagc aaataaatcc actgggcaaa
    10981 actacgatgg gcaaagaggt catcccagat agccttcata gttcctgaaa atcctaaatc
    11041 agccatagcc gcaaccatac gacggtaacc acctgacatt tcacctaggg ttgttttgat
    11101 attttcaatt ttcttttgca aataagtatg catcatttct ccttttgttt ttaaagagcc
    11161 gtgtctggat agactttcgg acgcaacgct ctattagata atgaactgcc tatacacaag
    11221 atttctaacc ttagtcgaca tgagctgaaa cctcttattt gttaagtagt tcacaaaata
    11281 ttatacacct attttatgaa tagtcaactg tctttacagt aaaattttag aaaatcatga
    11341 aaattttctc tttctttcca ttttaagtga cattcagtca ttctcacatc aaaaaagccc
    11401 agacgaaatt gtctgagcat tcttttatct agtcgtttaa ggaagttgag ttcagtatgt
    11461 ttaaagtctc tgtcccatca tttcttcaac aaaccttgtt cttggagaaa ctccttggct
    11521 acttgctttg ctgacttgcc ttcaacaccg acttggtagt tgagctggct catctggctt
    11581 tctgtaatct taccagccaa tgtattaaga actctttcca actctgggtg tttcttgaga
    11641 agagcttctt tcatgagtgg agccccttga taaggtggga agagttgctt gtcatcttcc
    11701 aagacctgta aatcataacg ctccaattcc gcatcagtcg aataggcatc cgtgatttga
    11761 atatcccctg actgaattgc ctgataacga agagctggct gcatagtcgc cacattgaga
    11821 ttgagaccat acattgattg caagccctta tttccatctt cacggtcgtt aaactcaagc
    11881 gtaaagcctg ccttcagctg cccttccact tttttcaaat ccgaaatggt cttcaagcca
    11941 tattcttgag caatcttttt cggaacagct acagcatagg tattttgata agacataggt
    12001 ttgagatagg ctagatgatc ctgcttggca atgccatcac gcgccacttg ataaacctgc
    12061 tctggctcat gactcacctt gggtgatggt tgaagcaaac tttcagtcac cgtaccggta
    12121 aattcaggat aaatgtcaat atcacctttt ttcagagctt cataaaggaa acttgtcgtc
    12181 ccaaaattcg gtttaacagt cgcagtcatg ctggtatttt cttcaatcag caatttatac
    12241 atattagcca aaatttctgg ttctgggcct attttcccag caataatcaa gttttccttc
    12301 tctttttgag ccaaaagggc tggactataa gacagaccca gtaataaagc caccaaggca
    12361 aaaccagaga aaatcgtccg caatttcgct ttttccatta cttttagtag gaagttaaag
    12421 gcaatagcta gcactgcaga agaaagggcc ccaatcaaaa tcaaactggc attattacgg
    12481 tcaattccca acaggataaa ggaacccagt ccccctgccc caatcaaggt cgccaaggta
    12541 gccgtaccga taatcaagac cgctgccgtc cgaattccag acatgataac aggcatggca
    12601 agtggaattt caaacttctt gagacgctcc catctggtca tcccaaaggc aatcccagcc
    12661 tcttgaagac tcggatcaat tcccttcagc ccagtaatag tattttgtaa aatcggaaaa
    12721 atcgcataaa tcactagagc tgtcaatgcc ggtaaagtcc caattcccat caagggaata
    12781 aagagtccca acaaggccag agacgggatg gtctggaaaa tccctgcaat ctgtaagacc
    12841 caatccgcca acttctcatg atagcgaaga taaacagcca agggaatcgc aagcaaaata
    12901 gctagtaaca aggtcaaaag tgacaactgc aaatgttgag atagggctgt caaccaatca
    12961 ccaaaacgat cctgaaaagt tgcaattaaa ttagtcatga atactacctc caaacaagtc
    13021 tgcaacaaag tctgttgcag gagcttttaa aatagtctca ggattcgaca cctgacgaat
    13081 ctctccatcc tgcaaaacag caatacgatc tgccaacttt aaggcttcat ccgtatcatg
    13141 agtcacaaaa atcgttgtca tcccaaactc tttatgtaat tcttttgtca gaacctgcaa
    13201 ctgcttgcga gaaatagcat ccaaggctga aaagggttca tccatgagga gaatcttggg
    13261 ctgaccaatc atagctcgga caataccgac ccgttgctgt tctccaccag ataattcact
    13321 aggtaagcga tgcccatact cggctactgg taaaccaacc ttagccaaaa gctcttctgt
    13381 tttcttcgta atttcttcct tgctccaccc cttcatttca ggaatgagag caatattttc
    13441 cgcaactgtt agatttggaa aaagagcaat agcctgtaaa acataaccag tagaaagacg
    13501 aagttcacgc tcatcatagt ctttgatgcg cttcccatcc atataaatat ttccatcagt
    13561 tggttccaaa agacggttaa tcatcttgag catggtcgtc ttacctgacc cagaaggccc
    13621 tactaaaacc ataaattccc catcctcaat ctgtaagttg acatctctca agacatcctt
    13681 ttctgtgtag cgcagtgcta catttttgta ttcaatcatt ctttgtcctc aatttaaaac
    13741 ttccctcgat tagtcaagtc ttctacctta ggcatgactt ccttattatc ccaatgctcc
    13801 acaattttcc cgttctctaa acggaagata tcgtactggg cataagcaac gccatcaatc
    13861 tgagtctgac catagctaac cacatagttt ccttgtccta agagttggaa aacaaagtca
    13921 aaagtgacac tatattcagc cacatagttt ttataagcag cacttccttg tccaatctca
    13981 tgattatgct gaatcaaatc gtctgccaca taatcactcc actgctctag ctccccattt
    14041 tggaaaattt ctgtcaagaa acggcgaacc agctttttat tttctgcttt cttatccaaa
    14101 tccttgattt caaaatctcc aaaaatttga tctagttggt cattttcagg tgttcgatag
    14161 tagtcaatga catcccaatg ctcaacaata caaccattct catcctcacg gaaagtatcc
    14221 gtcgtcaccc attgagcttc tccaccattc agatattgat gaacatgaac aaagaccaga
    14281 ttgccatcct caatggtgcg gacaatctta atctgacgct ctggatgacg ctcaaagaaa
    14341 tctgcaaaga aggctgcaaa tccttctttc ccgtcaggaa cacctgtcga atttggatat
    14401 aggtatcccc tacagactgg gcttgagcct cagcaactcg cccgtcttga atggcatgga
    14461 tgtataggtt gtgagcattt ttcacttgtt gtgacatatt ctaaacctca tttcccttct
    14521 ctttcagatt cgccaaaatt ctttcttgaa aaccttcaaa ttggtgaatt tcttcctctg
    14581 aaaatccttt gtaaaagata gtatccaatt tctgactgac acgatgcccc acttctttct
    14641 gggacttgcc taactccgtt aaaactaaat acttcttacg cttgtctttt ccacacggac
    14701 taacaattac aagcttttgt tcctctagct tttttatcat agtcgtcagc gtattattcg
    14761 caagcccagt cgcaagcgcg atatctgtcg cagttgcgca gccagtttca ctattccata
    14821 aaaccgctaa aatcttgccc tgttcacccc tataaagagc ctcaggatct tgactcagta
    14881 acttttgaaa aatccgccca ttcaacaaac gaatatgatg ggctagcaaa tgactatctt
    14941 tcataacacc tccaatttat ttcgatatcg aaatgaataa aataattgta acactcatcg
    15001 ttctaactgt caactatttc gatttggaaa taatttttga taattatcca caccaccata
    15061 ctccggctca actaactttt aacgagagtt tctaaactcc ttcgtcctcc agtctacaaa
    15121 agccttccat tcgtactatc ctatatttta tgaggggaca catttttcct atcagaccat
    15181 ttattttaaa gatagaagta aatcataatt gcttccatct gttcttttat agtatattga
    15241 agttagacta gagcactgta tcttctaaaa cattgataga aagcgatttg aatttcccaa
    15301 tcaatttgtt cgtatttata gcatttcgaa actggaatag gacaccatga ctgctaaaag
    15361 atttctataa attcatttga ttttcctaat caatttgttc atatcttatt tcattccgct
    15421 ataatttcac cttaccctat ctttttcgta gcacccttca aacagcctat cccctaccgt
    15481 ttgacgattc ctcacttcac tccacttcca ttacagaagt ttcttcacta ctatggtctc
    15541 ggctgacttc tcatgattcc ttgttactac tatttgaacg ctcacgagat aagtcttata
    15601 aaaaatgctt tgatccacaa tggaatcaaa gcattttaaa aagttcctca tacataagcg
    15661 cagaagtcgc agttcctctg tacttggctt cttctctttt gacaaagcga gccaagttga
    15721 gcaactcagg tgctggatgt ttgggattta ggagcaattc acgattgacc aggcctgaga
    15781 gacgagctgc ctgcaattgc tcatttgtag taggcagttt tttagtagtc tctaggagag
    15841 cagcaactaa atcttcactc aaatcatgtc gagcatgatt gtaaagatct tttataaggc
    15901 tttctaggtt tggttctacc atccctacca cctcccttat ggtttaataa tgtttaatca
    15961 aatcaaccgt tgaacgatcc aatttcttca ccaaggcttg taagaaagct tgcgcttcta
    16021 ggaagtcatc cattgcatag agggtttggt gagaatggat ataacgagcg cagacaccga
    16081 tagttgttga tgggacacca ccatttttca gatgagctgc acctgcatct gttccgcctt
    16141 taccacagta gtattggtac ttgataccag cttcttcagc cgttgtcaaa aggaaatcct
    16201 tcatccctgg gagaagcaag tgacctggat catagaaacg aatcaaggtt ccatctccaa
    16261 tcttgccttg accaccgtag acatcacctg ctggtgagca atcaactgcg aggaagactt
    16321 ctgggtcaaa cttggttgta gaggtatgag cgccacgcag accaacttct tcttggacgt
    16381 tagaacccag atagagttca ttgccgagtt tttgacccga taaagcttca gctagctcgc
    16441 ttaccatgag gacaccgtag cggttatccc aagcttttga gatgatattt ttttcattgg
    16501 ctgtcaaaat tgcagaacta tctggtacaa tggtatcacc aggacggatg ccaaaacttt
    16561 ctgcctcagc cttgtccgca aaaccaccat caaaaacgat atcggcaatg gctggcatgg
    16621 ttggtccccc ctttccacga gtcaaatgcg gaggaacaga acctgaaatc acaggaattt
    16681 catgaccatc acgagtcaag agtttgaaac gttggctgct aaccaccatg gggttccagc
    16741 caccgatttc tacgacacgg aaggtaccat ctggcttgat ttcgctgacc ataaaaccaa
    16801 cttcgtccat atgagaagcg accaagacgc gcggtgcatc cacagcttct gaatgtttga
    16861 taccaaaaat accacccaag ccatctgtca ccacttcatc cacatgcggt gtcaactttt
    16921 cacgaagata agcacggaca ggcgcttcat gacctgagac tgcagcaagt tctgttactt
    16981 ctttaatttt tgaaaataat gttgtcattt cagttccttc tttctttcat ccattttacc
    17041 actttttata ggagaaggat agtgggaagg tggatttcta agttagtatc ttagtcctgc
    17101 tctatcttag aaaaggatag tattctcttg catgtagtgc aaaatctagt aaacattcca
    17161 aaattaactc gaatatttat ttccaaacaa aaaaacaata caccatcaaa gttgtttgga
    17221 tttttcatga aatttacaga aaatagttga cttccctttc ttctttcttt aaat
//
LOCUS       DAVMCN010000036        16588 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVMCN010000036 DAVMCN010000000
VERSION     DAVMCN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16588
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.036"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(150..308)
                     /locus_tag="VYP85_001425"
     CDS             complement(150..308)
                     /locus_tag="VYP85_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881921.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(318..1628)
                     /gene="obgE"
                     /locus_tag="VYP85_001426"
     CDS             complement(318..1628)
                     /gene="obgE"
                     /locus_tag="VYP85_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1881922.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(1692..1826)
                     /locus_tag="VYP85_001427"
     CDS             complement(1692..1826)
                     /locus_tag="VYP85_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1881923.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(1885..2061)
                     /locus_tag="VYP85_001428"
     CDS             complement(1885..2061)
                     /locus_tag="VYP85_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1881924.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(2092..3417)
                     /locus_tag="VYP85_001429"
     CDS             complement(2092..3417)
                     /locus_tag="VYP85_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1881925.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRSSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(3433..4476)
                     /gene="cpoA"
                     /locus_tag="VYP85_001430"
     CDS             complement(3433..4476)
                     /gene="cpoA"
                     /locus_tag="VYP85_001430"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1881926.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(4591..4920)
                     /locus_tag="VYP85_001431"
     CDS             complement(4591..4920)
                     /locus_tag="VYP85_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1881927.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(4934..6043)
                     /gene="rpoD"
                     /locus_tag="VYP85_001432"
     CDS             complement(4934..6043)
                     /gene="rpoD"
                     /locus_tag="VYP85_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1881928.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(6046..7806)
                     /gene="dnaG"
                     /locus_tag="VYP85_001433"
     CDS             complement(6046..7806)
                     /gene="dnaG"
                     /locus_tag="VYP85_001433"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1881929.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(7896..8654)
                     /locus_tag="VYP85_001434"
     CDS             complement(7896..8654)
                     /locus_tag="VYP85_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1881930.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(8651..9517)
                     /locus_tag="VYP85_001435"
     CDS             complement(8651..9517)
                     /locus_tag="VYP85_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881931.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMDLMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(9586..10590)
                     /locus_tag="VYP85_001436"
     CDS             complement(9586..10590)
                     /locus_tag="VYP85_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1881932.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(10703..10920)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11003..13699)
                     /gene="ppc"
                     /locus_tag="VYP85_001437"
     CDS             complement(11003..13699)
                     /gene="ppc"
                     /locus_tag="VYP85_001437"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1881933.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFDSSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(13719..14948)
                     /locus_tag="VYP85_001438"
     CDS             complement(13719..14948)
                     /locus_tag="VYP85_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1881934.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(15104..15406)
                     /locus_tag="VYP85_001439"
                     /pseudo
     CDS             complement(15104..15406)
                     /locus_tag="VYP85_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(15854..16075)
                     /locus_tag="VYP85_001440"
     CDS             complement(15854..16075)
                     /locus_tag="VYP85_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1881935.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
BASE COUNT         4935 a         3673 c         2883 g         5097 t
ORIGIN      
        1 ttttactgtc ctgatcgatt tgtcctgttc tcatttcatt ttactatatt ttagaagata
       61 tgctgtgcta ttccagattc agtttgctat acatgcctgt cgtaccacaa aatcccgtgt
      121 ctgatgaggc acgggatttt ttagcttctt tactgagatg gattttcctt tttagttcgt
      181 gccaatctca aggcacgatt tggattgaga cgattaaata gttcttccaa tttcttttca
      241 ttccaaacgt ctgcggcgga aacaaaatta ccatccgcat ctcggaaaga tatcggttta
      301 tctcccatac cagtctccta gtctacaaat tcaaactcaa atttaccaat gcggaccaaa
      361 tccccatctt tagctccacg cgcacgaagg gcttcatcaa cccccatacc acgaagctga
      421 cgggcaaatt tcatgacaga ttcatcacga tcaaagttgg tcatattaaa gagtttcatg
      481 agtttttcac cagaaagtac ccatgtcgca tcgtcatcac gactaatttc aaaggctttt
      541 tcttcttcgt caaatccata gtaagcttct tcttccatat cggactcgtc gtagagcaaa
      601 aattctggtg tcttgtctaa caattcagct gtagcatcta aaagtgttgc cagaccttgc
      661 ttggtcaatc cagaaattgg gaagatagct ggtaactctt caaattcatc ataattttca
      721 gccaattttt tcttaaagtc ttcaagattt tcctgactct caggcatgtc catcttatta
      781 gctacaataa tctgtggacg ctccatgagg cgaagattgt aagactccag ctctttattg
      841 atagctaggt agtcctcata tggatcacgg ccttcgctag ctgacatatc aatgatgtga
      901 aggataacac gtgtacgctc gatgtgacgg aggaactgag ttcccaaacc aacaccttga
      961 ctagcccctt caatcaaacc tggcaagtcg gctactgcaa aggattcacc tgattgggtg
     1021 cgaaccatac ctaaatttgg tacaatagtg gtaaagtggt aggcaccaat tttaggctta
     1081 gctgaggtaa taacacttaa aagtgttgac ttccctacag atgggaatcc tactaaaccg
     1141 acatctgcca agatttttag ttccaattgt aactcacgtt cctgacctgg ttctccattt
     1201 tcagagattt ccggtgcagg attttttggt gtcgcgaaac gaatatttcc acgtccacca
     1261 cgaccaccgt gggcaacgat aaattcttgc ccatgttcaa tcaaatctgt taaaaccttg
     1321 ccagtctccg catcacgaac agtcgtacct tgtggtactc gaactctaag gtcctcagca
     1381 ccacgaccat gcatcccttt ggtcatccct ttttcaccag aatcagcctt gaaatgacga
     1441 ttgtagcgga aatccatcaa ggtacgtagt ccttcgtcta caacgaagac cacattgcct
     1501 ccacgaccac catcaccacc ccaagggcct ccattaggga catatttttc acgacgaaag
     1561 gcaaccatac catcgccacc attaccagcc ttgaccttaa tcttagctgt atctaaaaac
     1621 atactcatta tttcttctca ctttaaaaaa gggctgggaa atcccagtca ctaaattttc
     1681 ttgaatctat tttatagatt actgagggca ccaattgcag ttgcaaaaat tcccaataaa
     1741 cttgctacta gcatgataat cacgataaac aaggttattt tctcaaacat agttttttta
     1801 cgatttccat tatctccaaa tgccattttt ctctccttcg ttacattcta ttttctatta
     1861 tcttagcatg aattgagcta gttttcaata gtcagttgct actggtgcga taatccataa
     1921 aataatgtaa gctacaattc cagctccgta acagcaagta agaacacccc aaatgacttg
     1981 aacgatagtc ggatccatat ccagataatg ggccacccca gcacaaacac ccgcaatctt
     2041 tttatcacga ccgcttctca ttaattgttt ttttcatagc tgttcctctt tctattcttc
     2101 atggtctttc caatagtctc tcatactgat caactgtgtt tttgaagcct tcaacatgcg
     2161 tctagatcct tttacaggta cagcaaccac ctgttgctga agatacaaaa ctgtcttaaa
     2221 gatacgctga ctgaccgtat catctttagc caaatctttc tggaagttat ttgaaataat
     2281 ggcatccaga taaaactcat gcactcgttt cccaaagttc tcagctgaaa tctcatacaa
     2341 tttctctgat aaggtatgct cgttcatgtc tggtgttgca atcagggctt ccaaaatagc
     2401 accagccaaa tcatgttctc catagtacaa ggttccaaac attttatcac tgatgaggtt
     2461 gttcaaataa ggatttccgt gagcaatgac aggtgttcca ctggctaagc tttccaagta
     2521 ggtcaaacct tgcgtttcgc ttgtcgatgc cgaaatgaag aaatccgccg ctttatagta
     2581 aagagccgtc tcactaggag caatcatccc tgtaaagatg actgagtctt gaatctctag
     2641 gttctgggct tgctctttga ggtcattcag ataagggcca tccccagcta ctaccagttt
     2701 aaccttgtct tcctctttca gaacatcagc aaaggctgct aaaactgctt gaatattttt
     2761 ttcataggag attctcgaaa gactaagcaa cgtcttttca ccatcttgaa tccctagttt
     2821 actacgcagt tctttcaaat tttcctgctt gatttccgga cgctcaaact tggctaattc
     2881 aatcccagta ggaatgaccc gtttttcaac cttgacctta taatcagata gcaagtcacg
     2941 gacaatctca ctagggcaaa taaccccatc cacatcatgc aggaaacctc taaccagata
     3001 cttgaccata ctcgaccgga tcaacatccc cttagcaata taatggacat agtcttcata
     3061 ctgggtgtga taggtatgga tgactggaat tttcaattca cgcgcaatcc aaatccccaa
     3121 caggccaaga gaaaattctg tctgagtatg gataatatct agctgatact gtttagcaat
     3181 ttcaagtgcc ttgctaaaac ctcggtaggc aaagcgacga tccttaaaag caaagaaagg
     3241 aacacttgga atgcggataa tttgccaatc ttcgtagcga ttgacatcct tatctgtcgt
     3301 cgtaaagata aaaacagcat gtccctgctt ttcaagttct gttttcaagg ttcgaatact
     3361 ggtcgcaaca ccagaaacct gaggaaaata ggtatctgta aataaaccaa ttcgcataga
     3421 ttacctcact ttttactttc tccctaaagc ggcttgtttc tcataaaagt ccaaccagat
     3481 ttgtaacaga tgctcttcag aatactctct ggaaatattc ttggcctttt ctttgagatc
     3541 ttttaagaca gcaggatttg cttgatattc caaaatagcc tctttcatct cttctctacc
     3601 cgctgtcgcc cgataatttc cctccaaaat caccttatag agatctaaat cacgcaacat
     3661 aataggagcc tcacaactcg cagcttctaa aatagtcata ggaaagagct cattgtaact
     3721 aggcaacaag aaaagatccg ctagagcata caattcgcgc atccgctctg gcgatacaat
     3781 gcctggaaaa atcaaatttt tagggggatt ttccataatt ttcttatagt gttcataacc
     3841 atctgtcata ccaccaaaag agaagccacc agcccagata aaggtaatct gaggcaattc
     3901 ctcagccaga cggataaagt catcaatccc tttacgtttc tgaacttgcc cagcacctac
     3961 tacgataaac tgattgtcac taagaccaag atctgtgcgc agtctgacta cctcttcttg
     4021 tggtagagga tgccattttt ccttgttgac aaagttagga atataggtca ctttttcacg
     4081 tggaatacca gctgctacca aatcctcaat aaacatagga ttgaccacaa ccaagtgctc
     4141 catccggttg taaaaagaaa atacatagcg tttcacaatt ccctttaaga aaaatggaat
     4201 tttcaaactt ccttcaagtg tagctggcaa gaaatgcaca tagccaatct ttctccctga
     4261 gcgtttcttt tggaaggttg ataaataata gggaaaatca atcgtatgaa agtgagtcac
     4321 atctgcctcg attggaagat tttctgtaac aatcaattgg tccttggcag cacggtgaag
     4381 aagacgaact aattcacggt aagcacctga aactccctgt cctgctactt tctcacttga
     4441 actcaacata ttgatgcgta atttcttttt ctccataact actattatat cattttcttt
     4501 gaataaaatc agcaaaagaa aggagagact agaggaaaag aggggaaatt tcctcgcttt
     4561 tccaacagtc tctcacatgc ttttatatgt ttacttaatg cctagggcaa tgcgggcata
     4621 gcgactcatt ttttcaactg tccaggctgg ataccagact aatttaacct cagtatccgt
     4681 tacttctgga acctctatca tagcatcata aatctggtct gtcaaaaggt ctgctaaggg
     4741 acaacccata gttgtcaaag tcatgtcaat ctctgtttgc cctgtgtcac cgtcaaaacg
     4801 aatctcatag atcaaaccaa gattgacaat atcgattccc aactcagggt cgatgacttc
     4861 ttccaaggct gttaaaatcc gtgttttgat gttttcaatt tgctcttctg tataagccat
     4921 attttcctca ctcttagtct tcaataaaat cacgaagcgg tttgctgcgg cttggttggc
     4981 gtagttttct caaagccttt gcttcaatct gacggatacg ctcacgagtt acgttaaaga
     5041 ctttccccac atcttcaagt gtgcgcattt ttccatcatc tagtccaaaa cgtagacgca
     5101 gaacattttc ttcacggtct gtaagagtat ctaagatttc atccaattgc tcacgcaaga
     5161 cgatacgagt cgtataatcc actggatttt caattacttc atcttcgata aagtctccaa
     5221 ggtggctatc gtcctcttca ccgataggag tttcaagaga tactggttct tgggcaatct
     5281 tcaagatttc acgaacctta tcaggtgtca tatccattcg ttcagcaatc tgttctggtg
     5341 tcggatcttg ccccaattct tgaaggagat tccgctgttc acgaaccaat ttattgatag
     5401 tttcaaccat gtgaactggg atacggatgg tacgagcttg atccgcaata gcacgagtga
     5461 tagcctgacg aatccaccaa gttgcataag ttgaaaactt gaacccttta gaatagtcaa
     5521 acttgtcaac cgccttcatc aagcccatat ttccttcttg aatcaagtca aggaactgca
     5581 tgccacgacc gacatagcgt ttggcaatag aaacaaccaa acgaagattg gcttccgcaa
     5641 gacgttgttt ggcttcgata tcgccagctt caacagccag tgccaactct ttctcctctt
     5701 cattggtcaa gagaggaacg acccctattt ctttcaagta catacggaca gggtcattga
     5761 ccttagcaga agttgaccca atcaagtcct catcgctgag ttctggttct tcttcattgc
     5821 taagaacacg cgcacttgga tttccttcgt tatctgtgat agaaatgcct gcatcctgaa
     5881 tccgttgcaa gagatcttca atcccatcag cgtccaaggt aaaaggaata accagacttg
     5941 cattgatttc atcatctgtt gctgtccctt tttgcttatg attacggata aattctgcta
     6001 cctgtacgtc aaatgttgtt acttcttttt gttttgttgc cattattact ccattcttct
     6061 cttttgggaa attaaacgtt ccaattcttc tagggctgta tctgtatctc ctacatggct
     6121 agcttcctgc accttctttt tgattctcat attgtcctga ttcaagagag ccttgtttcg
     6181 agtcatctct acttcactaa gttcctgcgg cgatatctca gcaggcaaat cctgagctaa
     6241 aacttggtac caagctcttt caacttcctc tgtctgctct gctaaaactt ctggaggaag
     6301 atttccatac tggccaagca agtcatataa gacctgaaat tcaggtgtag caaatgcaaa
     6361 gtcttctcgc aaacggtaat cgttcaaaac aagaggggat tccatcatcc gatagagtag
     6421 atgggcttct gccctcataa tagccgataa ctgcttggtg ataggcatgg tgattggcgt
     6481 cggtctggaa attccttcca tgcgattctg cctttgcacc tgacgactct cattaacaat
     6541 ctgctcaatc tgggtataat caaaggacgc cagactgtca gctaaaatat gaatatagct
     6601 gttttgagca gcgatggact tttcttgaac aatcaaggga gctatttttt caataaactc
     6661 aatctgagcc tgcagatttt cactgttttc aggtttgtac tgatgaatgt agaactcaat
     6721 cggactaata cgagtttttg ttaatagata ggccaagtct tctggaccat ttttttgtag
     6781 atactcatca ggatccaagt tatcaggcat gctaacgatt tgcacaggca tatcaccaat
     6841 ttcatccaat gctttcaata tcgcggcttg cccagcctta tctccatcgt aaacaagaac
     6901 caatttcttg gttaaccttt tcagatgctc aacatgctct cgactcaagg ccgttcccat
     6961 cgacgccaca gcattttcga ttccagcccg ataggctgca ataacatcca tgaatccttc
     7021 catcaggtaa atctcactag cttttccaga agatcttttt gccctatcca tatgatataa
     7081 ttcgtaactt ttgttaaaaa ttgcagtcga tcggctgttt ttatacttag aagtttgtga
     7141 atccgttttt tgccagatac gacctgagaa ggcaatgacc tttccttggt catttgtcag
     7201 gggaaacata atgcgattgt gaaaggtgtc tacaaattga ttggcatccg agagataaaa
     7261 caggcctgaa tccagtaaat cctcttcacg atactgatca gacaaacgtt gatagagata
     7321 gtttcgttct ggaggtgcta aaccaatcca aaaatgttta agcacttcat ctgtcaaacc
     7381 ccgctgataa aggtaatttc tggcctcttc tcccatagtc gttgtcatga gaatagcatg
     7441 gtaaaatttg gctgcatctt cgtgcatatc ataaagagct tggtgaggcg aggctggctt
     7501 ctgttcacta taaagcggtt tttcaacctc aatcccgaca cgctgaccta agatttggac
     7561 agcctccata aaggtaaccc cttggtactc ctcgatgaat ttaaagacat cacctgagcg
     7621 accacaacca aaacagtggt aaaactgctt atcctctaca acgttgaaag aaggtgtttt
     7681 ttcaccatga aaaggacaga gccctagata gttccgtcct gccttttgta aagaaatcac
     7741 atctcctatg acttccacaa tgttggcatt gtttttgatt tcttcaatga cttgtttgtc
     7801 aaccatacac aatacctcca tgttatcata gtttacttta tatagtatac tttatttcag
     7861 aaaaaaagta aaccatttca ctcattttcc ctactttatt caaagagttg ataataatca
     7921 gagattttca tttttgcttt ttcttcttgg tttaaatctt ggataatccg tccttctttc
     7981 atgacaatca agcgattgcc gtatttgaga gcatcttcca tatgatgagt aatcataagg
     8041 gctgttagct gatctttctt aacaaattca tctgtcaatt ccatcaaagc aacactagtc
     8101 tttggatcca gggcagcagt atgctcatct aacaggagta attcaggtcg cttcaaggtt
     8161 gccatcaaga gactcaaagc ctgtctttgt ccacctgata agaactcaat cggtgtattc
     8221 aagtgtttct caagaccatt tcctactttt tcaatggttg cctgaaattc atccttatag
     8281 ctagtcaagc gtcttggtaa caatccacgc ttttcaccac gaaacttggc gattaaaaga
     8341 ttttcagcga ccgtcatacg gggagctgtc cccatctttg gatcttggaa gacacgagac
     8401 aggtacttgg cacgcttctc gggtgaaaac ttagtgagat cttcacctaa aatacggata
     8461 gttccactag ttagtgataa ggtccctgct atagtgttaa agagagttga ttttccagca
     8521 ccatttccgc ccaaaatcgt gataaagtcc cgttcaaaaa tttctaagga aacatcattt
     8581 aaaataatct tttcttcatc aaagccattt ttaacgattt tggttgcatt ttttaattct
     8641 acaattgctg tcatttgctt aacttggctc ctttcaagat tgtttgctta aatgttggaa
     8701 tcatgaggca gactgctaaa atcaaagcac tgtataaacg aaggtaactt gtattaaagc
     8761 caagtgcgat aactgcccac actaaaaatt gataagcgat agaacctaca acgatagtaa
     8821 ccaaacgctc tgccaagctc aaactcttga aaataacttc tccaataatc aaacttgcaa
     8881 gccccacaac gataaccccg atccctcgag acacatcggc atagccttct tgctgagcaa
     8941 tgagggcacc tgcaagggca atcacaccat ttgataagac caagcccatg agatccatgc
     9001 gtccagtatg aatcccgaaa cttctagcca tatcaggatt atcccctgta gcaatatagg
     9061 cttgtccgag tttagtgtcc aagaaaaaga gcatgagagc aataacaatg ctcacaaaga
     9121 tgagacctgt caagagttga ttcaaatccg aatcaaaagg caaaacatcc tgaatttgct
     9181 tggttccaag caggcctaaa tttgcacgtc ccataatcaa gagcatgatt gagtgacaag
     9241 aagtcatcac caaaatccct gagagcaagg ttgggatctt cccttttgta taaagaaggc
     9301 ctgctgccat tccagccaaa caacctgctc ctacagcaac aagtgtcgct aaaaatggat
     9361 tcacgccttt ggttatcaaa gtgacagcaa cagctccccc aagagggaag gaaccttctg
     9421 tcgtcatatc tggaaagttt aaaatcctaa atgtcataaa gattcccaga cctagaatag
     9481 cccagacaaa tccttgagaa ataatggaaa caatcatatt ttatttaatc ctttctatat
     9541 tcatcttttt aaaaaatggg aagagtctcc tcctccctac cttatttatt cgatgacttg
     9601 tcctgcttct ttgagaacag actcaggaat agtaatacct agttcttgtg ctattttttt
     9661 attgatgact gacttaccag ttgaaaagac attgactggg gtatcggctg gttttgcacc
     9721 tttcaagact tgcacaatca ttttacctgt tgccacacca aggtcatgtt ggtcaattac
     9781 aactgatgcc aaaccaccta cttctaccat agctgtcgca ctgggataaa ttggtttctt
     9841 agaactttga ttgctagaga caaccgttgg aaatcctgat gcaatggtgt tatcaattgg
     9901 aacccaaata gcatctacct tgctagtcat aacagtgaca gttgaggcaa tttcatttgt
     9961 tgaaggaact gcaaatgttt ccactgtcag acctgctttt tcagcataag ccttaaattc
    10021 ttcgacctgt gtttttgaat tgtcttcgct acttgagtaa agagctccga ttgttttcac
    10081 attcggtgtc agagccttga tgagttcaac ttgttgttga gctggattgt ggtcagatac
    10141 ccctgtaacg ttgccacctg gttttttcaa atctttaacc aagttagcac caattgggtc
    10201 tgtaatagcg gccatgataa ccggtaggtc ttttgttgca ctagccaacc cttgggctgc
    10261 tggtgttgcg ataccaacca caaggtcatt cccatttgca accaattgtt tactcattgt
    10321 cgcaacctta ctttggtcac cttctgagtt cataaaatca attttaactt gatcatcttt
    10381 atatccttct tctgcaagtc catcttggat ccctttataa atcaaatcaa gggatggatg
    10441 gctcacaaat tgaagcacac caatcttggt tattttcttc tcatccttat tattctgaac
    10501 ttctgattta ttcattgaag aataaatcaa gcttcctgct actaagactg ctaatgcagc
    10561 aataattcca attaaacgtt tatttttcat tctgtttctc ctttttattt cctttaacat
    10621 atttcactta tctaaacaag cgacgccatt gttttctttc catactaacc tccatcaaaa
    10681 aaatcctcac acaaaaaact tgtgtgagga cgtcgatgcg cggtaccacc tcaattatag
    10741 ggaatttccc tatcgctcag tctcgcaata acgagatgca ctgtaaggtg tgcttaccga
    10801 atttttataa tttcaaattc taaatagcat tcagcccaat tttcatcatt gccacttatc
    10861 tgttttcagc taccacagac tctctaaaaa gtttgtatga ttacttttct gaatggttaa
    10921 attatatcat ttttaaacta cttgtcaata gtctattaga atttttttga tattcacttt
    10981 tagcattcac tcttgaaaat tatcaacctg aattacgcaa tcctgtcgca attccgttga
    11041 tggtgatatg aatcaatcgt tcttgatcac tggacaattc tccacgacgt tggcgtttaa
    11101 tcaactctaa ctgaatatag ttgagaatat taaagtaagg catacggtaa tccagactag
    11161 cttttagata tggattgtca gctaagagtt cgtcatgtcc ttcaatagcc aagataacgt
    11221 tcttagtaac ttgccattca tttaaaatag tctcatagat ggccttaact tgctcgtctt
    11281 cacaaagttt agcatattca aaagcaatat tcatatttga ttttgacaaa accatatcaa
    11341 catttgaaag aagcgattgg aagaaaggcc aattttggta catatctcgt aagatagcaa
    11401 tattctctgg atttttattg ataaattcct tgaagcttga accaaccccg taccatccag
    11461 ggaacataac acgactctgt gaccatgaga atacccaagg gatggcacgc aatccaccga
    11521 tttcagtaat agtcttacga gcggctggac gagaaccaat attaaaactt gaaatagcct
    11581 tgattggact tgaatcgaag aaataatcat agaaatgctc attaccaaag accaaatcac
    11641 ggtagatatc gtaactacgg tccactactt gatccataat ggcttcataa cgatttgggg
    11701 tattggtatc gctcttcttc tgagtaatca tacggttaat agctgccgat actagcattt
    11761 caaggttata gtaagcggcg tctttgttac cgtatttatt cccaattact tcaccctgct
    11821 ccgtcaagcg gatacgatcc ttgatagact tgagcggttg agatgtaatg gcttcatagg
    11881 ttggcccacc accacgaccg acagtaccac cacgaccatg gaagaaggta accttaacgc
    11941 caaattcatc tccaatagca gtcaattgtt gttgagcctt gtagagggtc caacatgatg
    12001 acaagtaacc gccatcttta ttactgtcag agtagccaag catgatttct tggtagttat
    12061 ttcgtgagtc aatccatttt ttggcaaggc taagagaaag atattttctc attgtttcct
    12121 ctgaatgatc caagtcttca attgtttcaa aaaggggaac aatctgaaca cgcgcccttt
    12181 ccgtatccac cagtcctact tcttttaaca gaatagctaa ttctagcata tcagaaaggc
    12241 tggttgcatg tgaaatgatg gtctgacgga tgacatcatc tcccaactta tctttcaaaa
    12301 cacgagccgt cttaaaaata gctaattctt ttgctaataa ttctgatttt tctgcgtgag
    12361 tcgcagaaag aattcgggga tcttcttcta attctttcaa gagaaggtca cacttttctt
    12421 cttcgctcaa ctcgctataa cgagaatgaa ttcctgctga tttcaagagt tctgccacac
    12481 aggcttcata gacgctagag tcttgtcgca tatcaattga cgctaagtaa aaaccaaata
    12541 tctctactgc ctgcaataat tccacaaaat cacctgaaat caaggactca cccttatttt
    12601 ctagtagaga atctcgaatg gcaatcaaat ccttgtagaa atcattggcg gtttcataac
    12661 gagtcccaac ttcttcatcc tcaatcagat aggttttagt tgcctgaatt tttgattgaa
    12721 tatcaaacaa ggcacgacgg taaagctctt tttcgcggta aatagagtta tccttggatt
    12781 gacgagccat ttctctgact tgcttgctga cgttgacaat gctagttgaa agagaaaatt
    12841 cacgataaag ttggtaaatc tttttatcat agtagttcat gatgacttca cactgagtga
    12901 gtgcagactg cttcaaggtc tttgctgtaa caaatggatt tccatcacgg tcaccaccta
    12961 tccacatacc catggtgatt ggtttagcct gttttaaatt cagaccatgc gcttgcgcta
    13021 agcgcttata ctccgtcgtc aaatgaggga cagctttcaa aaaggagctg ttgtaatatt
    13081 ccatagcatt cgtgatttcg ttagtcactt ttaatttttt ctcacgaatc atgtctgtct
    13141 gcatgataat ttcgatgtaa cgacgcaaat cattgtgcca tttatcttta ttgattaacc
    13201 ccaacttaac atcacggtat ttacgcaaaa gactatgaat atgatttgtt aaatccaaca
    13261 tacttttgcg ttgcacttgt gttggatggg ctgtcaaaac agggacaaca ttcaagtgtt
    13321 ctaggatctc aacggcattt tccttttctg ctaccaattt aatcgttgta gataatttac
    13381 ctaaatagtc ctgatcaata ttattttgat gattgatttc ataagctaaa tccacatcct
    13441 ctgaaatatt aatcaaaaga ggtaagatag agaaatagcg tgaaatatag accatttcat
    13501 catttgataa gctagtcact agacggttta gaccttgata atcttcctgc gttgataatt
    13561 ctttcaactg tattattttt tcaaaggtct ctggggcaag catattttta gtaatatctt
    13621 ccagtaattc tgttagaatc aagacttctt ctttcacaac acttttatta ctataatttt
    13681 ctaatttttg aagagacata aactatcctt tctttatcct acttcaacag aaggttcatt
    13741 ggttgatttt ccaattctcg gtacaactta gcgcgttttt cactggcatc aatatttaag
    13801 acaaaggcta ctgccactga taagactaga agactatttc caccctggga taagaagggg
    13861 aaagtcactc ctgtagatgg aatcaagccc gaaatccctc cgatattgac aaatacctga
    13921 accaacatca tccctccgac accgagtgca accatggcat tgaaaggatt ctccgctcgg
    13981 ataccgacca agataatccg caaaatcatg aaaaacaaga gagctaaaat aagactggca
    14041 ccaacaaagc caaattcttc aatcacgata gaaaagacaa agtctgtatg agcttctggc
    14101 aaataacctc gtttttcaat cgagtttcca agacctagac caaaccaacc gccattgacc
    14161 atggcaaaat aagaattagc taactggtga cctgcatcag cacgatcggc aaaaggatta
    14221 aaaaaggcac taaagcgctt ggctacatag ccaaatactg gaatttttga aaaggtctca
    14281 acaccgatta ggctgatagt ggtcaagaca aagacagaag tggcagatac gagcgccaga
    14341 atggttgaaa accagcgata agcgattcca ctaactgtat acataatcaa ggaaaccaag
    14401 actaaaatag tcgcatttcc taaatcaggg aaaattccca aacttccaat cagaactagg
    14461 agaacgaatc gccaatcatt aaaagcacgg ggaagccatt gattttgagt caaaacttga
    14521 aaatcataag tagctatttc ttcttgctgt ttggagaatc ggtgagctaa ataccaaata
    14581 ataatgattt ttaagtactc agctggctga atagttactc ctgcaaccga aatccaaccg
    14641 tatgccccgt ttacggaaat accaataaaa cgagccaaga acaataaaag catttctatt
    14701 aatataacta aaatgattag tcgctcattt ctcaaaaaat ctagtctcaa tttataaatt
    14761 aaggcaatca gtatcaaact aacaatccaa aagattcctt ggtttcgaac caactgcaag
    14821 gcactcttgc cttcttcaat taaaatagca ctggtggtcg aatagaccac aatcaagccc
    14881 aaaatagata aaagcaagta gggaatcaag atggaataat ttaataagtg cctcttacta
    14941 atcttcatag catcaccact ctactaggat acagataaat ctgttccaaa ttccgtttta
    15001 ttttctagtt ttgattgcta ttataccatt ttttcagaaa gaaaaaaact cttaccttac
    15061 aatccttcga attttactgt ttttacagaa ttaaggcaga atttgaaatc gtaaaaccat
    15121 tttgaataag agttgcttca acccattgac tccgacggat taagttgctt tcgtgaatgc
    15181 caaaatcagc cgcaatttgt tcataagtgc tctattctcg catgtattga atagttacca
    15241 taaggagatc gtctaggatt aatttgcttt ttcgtccacc ttttgcgcgt ttacgttgat
    15301 aagctgtttt taacacagct aacatctctt caaaagtcgt gcgctgaaca cctacaagga
    15361 tcttgaaacg gctatcgctt aattgtttac ttgcttcatc atccatagtt ttattgtatt
    15421 gtatttttgt ttcgcaggaa gtctattatt cctttcgttc caaggttttt acgctttttc
    15481 aagcaatcct acacactcca cgtgatgcgt ctgtggaact caaaaggttc ggggaacctt
    15541 ttgaggatta attgcgtttc tctaacaaac tcacacattc aacgtggcat gactgatgaa
    15601 gtcatcataa gaatttcact tgctgctctt tctcggtggc agcctgaacg gtcagaagta
    15661 tcattgtata tcatttgtat catggcatat aaagtatcgc tctattttat tgatggtttt
    15721 aatatcgctc ttatcatggc gaaccattca aatctgctcc acaaatgagg aaagtaccat
    15781 tttggactat tcaattgtca aagaacaaat aaaaaaaatc ttcgcatttt cacactctat
    15841 gaaattgagg agattatttt ctaaagcgaa ttttatcagg aaaatccgtc aatcccaata
    15901 ggtagtctgt actgacatcg taaaagtttg agagagttac caatatatct gctgttaacg
    15961 tatgctcacc ccgttcaatt ttagcataag ctgagtctgt aaacgaaagt attttagcta
    16021 tttgtttttg ggtcaaatcg tgatcttccc tcaaatctct caaacgtctg tacatctagc
    16081 tttctcctga gaaaagtata atatataaaa ctaagaaatc attcaaagtg tccaaactgg
    16141 acattttgaa ctaaaattaa tttattaaac atatctcata agcatatcta ttataggtaa
    16201 gacaatatta agaaagacgg tcaaaatcta ttaaccgtct aaagatgtta taagctatta
    16261 aaaaatcagc agtaatccgg taacaaaagt cacataattt tgttaaggaa gggattaatg
    16321 atgtccagat tactactaac cagcaaattg aaaaatggtc aacatgatat ttctaatgtg
    16381 aatctcttac tttcagaacc taaaagttga ataatagcca ccccctactt atcaataaaa
    16441 ttttccgttg cattaacaga tgtatataga ccactccatg gatttcaaag caattaacta
    16501 gactttattt gtcaataacc acaaaattag attagaaaaa tcattaaaaa ttaattggag
    16561 tcctttgtga tgctttttca ataaaagt
//
LOCUS       DAVMCN010000037        16339 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVMCN010000037 DAVMCN010000000
VERSION     DAVMCN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.037"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(150..860)
                     /gene="treR"
                     /locus_tag="VYP85_001441"
     CDS             complement(150..860)
                     /gene="treR"
                     /locus_tag="VYP85_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1881936.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            1045..3012
                     /gene="treP"
                     /locus_tag="VYP85_001442"
     CDS             1045..3012
                     /gene="treP"
                     /locus_tag="VYP85_001442"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1881937.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            3190..4815
                     /gene="treC"
                     /locus_tag="VYP85_001443"
     CDS             3190..4815
                     /gene="treC"
                     /locus_tag="VYP85_001443"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1881938.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            5071..5319
                     /locus_tag="VYP85_001444"
     CDS             5071..5319
                     /locus_tag="VYP85_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1881939.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            5526..6320
                     /gene="racE"
                     /locus_tag="VYP85_001445"
     CDS             5526..6320
                     /gene="racE"
                     /locus_tag="VYP85_001445"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1881940.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            6317..7288
                     /locus_tag="VYP85_001446"
     CDS             6317..7288
                     /locus_tag="VYP85_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1881941.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKLSL"
     gene            7264..7785
                     /locus_tag="VYP85_001447"
     CDS             7264..7785
                     /locus_tag="VYP85_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1881942.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPY
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            7782..8243
                     /locus_tag="VYP85_001448"
     CDS             7782..8243
                     /locus_tag="VYP85_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1881943.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            8234..8974
                     /gene="xerD"
                     /locus_tag="VYP85_001449"
     CDS             8234..8974
                     /gene="xerD"
                     /locus_tag="VYP85_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1881944.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            8974..9702
                     /locus_tag="VYP85_001450"
     CDS             8974..9702
                     /locus_tag="VYP85_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1881945.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLVGRAQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            9721..10290
                     /locus_tag="VYP85_001451"
     CDS             9721..10290
                     /locus_tag="VYP85_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1881946.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            10277..10999
                     /locus_tag="VYP85_001452"
     CDS             10277..10999
                     /locus_tag="VYP85_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1881947.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            10999..11241
                     /gene="yidD"
                     /locus_tag="VYP85_001453"
     CDS             10999..11241
                     /gene="yidD"
                     /locus_tag="VYP85_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1881948.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(11466..12431)
                     /locus_tag="VYP85_001454"
     CDS             complement(11466..12431)
                     /locus_tag="VYP85_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1881949.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(12527..13279)
                     /locus_tag="VYP85_001455"
     CDS             complement(12527..13279)
                     /locus_tag="VYP85_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1881950.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(13276..14232)
                     /locus_tag="VYP85_001456"
     CDS             complement(13276..14232)
                     /locus_tag="VYP85_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1881951.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(14222..15181)
                     /locus_tag="VYP85_001457"
     CDS             complement(14222..15181)
                     /locus_tag="VYP85_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1881952.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSILFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(15604..16305)
                     /gene="galE"
                     /locus_tag="VYP85_001458"
     CDS             complement(15604..16305)
                     /gene="galE"
                     /locus_tag="VYP85_001458"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1881953.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
BASE COUNT         4584 a         3261 c         3772 g         4722 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaatagg ctccataata tccatagggg ggttacccac tacaaatatt atagagccga
      121 aaaaggctga gatctggtgt ctcagtcttt tatttcttgc gttttgcaaa atctacaaat
      181 ctaaatttct ctaacttatg gcgactttcg gtaaactgaa attggcgtcc gtcttggaga
      241 tagacttttg atttaatcga aacgacataa gggtctttgc caatgtccat gagaatcttg
      301 tctcggtcgc ttgagtggtc aatggtgatt tccttctgag cataatcaat aaggagtttg
      361 aggccatttt ctatataaga atagatagac tgctcagcaa tttggcgagt gagatttgga
      421 attagttcca tatccagata gtccgtatcc agaacggata ccagatcatc caccacacgc
      481 tggcggacca ccttccaaac catccgaaac tctgggaaac cggttatcag tgaggatttt
      541 ttatcaataa taatcttgtc cagactgacc acgttggttt tagagcgcag tccaagttct
      601 ttaactagtt cttggtagct ggttaggttg gatacaggga aattgacggt ttcttctttg
      661 acgacttgag aaccttgccc tcttatcttt ttgatcaatc cttcctcttg gaggagagac
      721 agggcctttc ggacggtatc acgactcact tgatattgct ccataaggtc gtgctcgcta
      781 ggaaggaaat ctccgacagc gtaagtctcg ttttgaatgg tttcttggat ttgcttaaat
      841 aattgttggt atttcttcat tttgcctgct taaataggtt tttagtctag tttaatgaac
      901 acctgtatct attttaccat acaagtgcta gaaaatttac aaaaaaacac cctttttata
      961 ccaaacaagt tgcagacaag tttggtatcg tttacaatat acttatcaaa tcaaacttgc
     1021 tttgacaagt ataaggagaa tcaaatggga aaatttgaac aagaagccaa agatctgctt
     1081 caggcaattg gaggcaaaga aaatgtgact gccgtaactc actgtgcgac acggatgcgc
     1141 tttgttttag gagatgataa gaaggctaat gttaaagcta tcgagtcaat tccagctgtt
     1201 aaaggaactt ttacaaatgc aggtcaattt caggtaatca ttggaaatga cgtgcccatc
     1261 ttttataatg attttacagc cgtttcaggt attgagggtg tttccaaaga agcagccaag
     1321 tctgcagcta agagtaatca aaacgtggtc caacgtgtta tgaccactct ggcggagatt
     1381 tttactccga ttattccagc cttgatagtc ggaggattga tcctcggttt ccgtaatgtc
     1441 ttggaaggtg tccattggtc gatgttggat ggcaagacca tcacagaatc ctctcagttt
     1501 tgggcaggtg tcaatcactt cctctggttg cctggtgaag ctatcttcca gttcttacca
     1561 gtagggatta cttggtctgt ttctcgtaag atgggaacca gccaaatttt gggaattgtt
     1621 ctcggaatct gtttggtatc gcctcagttg ctcaatgcct atgcggttgc ttcaacgcca
     1681 gcagctgata tcgcagcaaa ctgggtttgg aattttggtt attttactgt taatcgtatt
     1741 ggttaccaag cccaagttat cccagccttg cttgcaggtt tgagtctgtc ttatcttgaa
     1801 attttttggc gcaaacatat cccagaagtc atttccatga tttttgtacc ttttttgtca
     1861 ttgattccag ccttgatttt ggctcatact gtcttggggc caatcggttg gacaattgga
     1921 caaggacttt catcagttgt attggcaggt ttaacgggtc ctgtaaaatg gctcttcggt
     1981 gcaatttttg gtgccctcta cgctccattt gtcatcacag gtctgcacca catgaccaat
     2041 gccattgata cacaattgat tgcggatgct ggtggcactg ccctctggcc tatgattgct
     2101 ctttctaata ttgctcaagg ctcagccgtg tttgcctatt atttcatgca tcgccatgat
     2161 gagcgtgagg ctcaggtttc acttcctgca accatttcag cctatctcgg tgttacagaa
     2221 ccagctcttt ttggggttaa cgtaaaatat atttatccat ttgttgctgg gatgactggt
     2281 tcagcccttg caggcatgtt atccgttact tttaatgtaa ctgcggcttc tattggtatc
     2341 ggtggtttgc caggtattct ctctattcaa cctcaataca tgctgccatt tgcaggaact
     2401 atgctagttg cgattgttgt tccaatgctc ttgactttct tctttcgcaa ggctggtctc
     2461 ttcacaaaaa tagagggcga tacgaacttg caggcagaat tcgttgctca agaagaagca
     2521 gaatttgtga gccatgaacc agtagaactt acttcggtag aaattatcag cccactaact
     2581 ggccaagtga aagaattgag tcaagcgacg gatcctgttt ttgcatcagg tgtcatgggg
     2641 caaggtctgg tcattgaacc aagccaaggt gagttgacct ctccagttaa tggaacagtg
     2701 acggttcttt tccctaccaa gcatgccatc ggcattgtct ctgacgaggg agttgaattg
     2761 ctcatccaca tcggtatgga tacagtaggt cttgatggca aaggttttga aagtcttgta
     2821 gtccaaggag atcacgttat agttggccag caactgattc gttttgatat ggatgtcatt
     2881 aaggctgcag gtctggtgac agaaactcct gttatcatca ccaaccaaga tgcttataca
     2941 gcgactatta ctggaactta tccgacaacg atccaagctg gagcatctct catggtcgct
     3001 acacgaatct aatactcttc gaaaatctct tcaaaccacg tcagctctat ctgcaacctc
     3061 aaaatagtgt tttgagcaac ctgtggctag cttcctagtt tgttctttga ttttcattga
     3121 gtataattga aatagcacaa atagggacgg aagactgctt cctccctttt atcagaaaag
     3181 gagaaacaga tgacacttga taaaggaaaa gtagtctatc aaatctatcc aaaatcttac
     3241 aaagacacca ctgaaaacgg tattggggat ttccgtggga ttatcgaaaa aattccctat
     3301 ttagccaaac taggtgtgga tatggtctgg ctcaatccat tctatccaag ccctcaacgg
     3361 gataatggtt acgatatttc agattatatg gcagtggatc ctctttttgg tgatatggct
     3421 gattttgagg aaatggtgtg tgtcggtaaa gagcacaaga ttgactttat gctggacatg
     3481 gtacttaatc attgttcgac agagcatgaa tggtttcaga aagccctagc tggtgataag
     3541 tattatcaag actttttctt catccaagac caaccaacag attggcagtc taagtttggt
     3601 ggttctgcat gggcgccttt cggggatact gggaaatact atcttcacct atttgatgag
     3661 acccaggctg accttaactg gcgcaatccc aatgtccgta aggagctttt caaggttgtt
     3721 aatttctggc gcgacaaggg tgtcaaaggt tttcgatttg atgtgatcaa tttgatcggt
     3781 aaggacgagg tttcagtgga ctgtcctgaa aatgaaggga agccagctta tacagacaaa
     3841 cccatcgttc ataactattt gcgtatgatg aaccaagcca cttttggatc tgacgatagc
     3901 tttatgacag ttggggaaat gtcttctacc accatggaaa actgtgtcct ttattcgtcg
     3961 cctgatcgtc aggaattatc catgaccttt aattttcatc acctcaaggt ggactataag
     4021 gatggacaaa agtggacctt ggctcccttt gattttgaag agttgaagag tctttaccat
     4081 agttggggta aggaaatgag tgataaagac ggttggagtg ccctcttttg gaacaatcac
     4141 gatcaaccac gtgccttgaa ccgttttgtc gatattcaaa acttccgcaa ggaaggagcc
     4201 accatgctag cagccagcat tcacctgtca cgtgggacac cttatatcta catgggtgag
     4261 gaaatcggga tgattgaccc agactatgat tctatggctg attatgtgga tgtcgaatcg
     4321 cttaatgcct atcagatgct cttagaagaa ggaaagagtc agcaagaagc cttccagatt
     4381 attcaagcta agtcgcgtga taattcacgt attcccatgc agtgggatac ttctgaaaat
     4441 gcaggatttt caacaggcac tccatggttg aaagtcggta aatcctataa agatatcaat
     4501 gtagaaaatg aaatcaaagg tctgattttc accttctatc aagacttgat tcgactgcgt
     4561 aaggaaatgc caatcatttc agaaggaaat tacaaaccag cctttgaaga tagcaaacaa
     4621 gtctacgctt ttgaacgcca gtttgaggat caaaagttac tagtgctcaa taacttttat
     4681 gccaaagaag tggaaatcga cttgccagca gtctaccaaa atggacagat tttgatttca
     4741 aactatgaag atgcagaagt gtctgagaaa attctactca aaccctatca aacactggct
     4801 atttatgtaa attaatactc ttcgaaaatc tcttcaaacc gtgtcagttt tatctgtaac
     4861 ctcaaagcgg tgctttgagc aacctgtggc tagcttccta gtttgctctt tgattttcat
     4921 tgagtataaa cttagcaagg agacctcttt ttcagaaaag cagggttctt tttgctgtct
     4981 attccatcct tgaaagtgta gaacaaactg gtcagggtgg ctagtttgtg gtataatgaa
     5041 agggattcaa aaagaaacag gagaaaaatg atggatttac ttttagcaat tgtattgatt
     5101 gtgctagctt ttctaggagg agctcttgga ggaatgtact tggttcgtaa gcaaatcgaa
     5161 aaagaatttg ctgacaaccc acgtttgaat gctgaagcag ttcgtactct tttgagtgca
     5221 aatggtcaaa aaccaagcga agctaaggta caacaagttt accaccaaat catccgccaa
     5281 caaaaggcag cccttgctaa caataaaaag aaaaaataaa taaggaaaag tctgggatga
     5341 aagttccaga cttctcacta tgttggttat ggtttaggga tgagactttt tccttgcatt
     5401 ctattgatat ttgattatga ttaagagaga ggtagttgac attctatcaa gctgtcggtc
     5461 agttcgttca gtacaaggaa tcataatgaa cgatcaatca gaaaaaagac tagaaagaag
     5521 actgtatgga taatcgacca attggttttt tggattcggg tgtcgggggc ttgaccgttg
     5581 tgcgcgagct catgcgccag cttccccatg aagaaatcgt ctatattgga gattcggcgc
     5641 gggcgcccta tggcccccgt cctgctgagc aaattcgtga atatacttgg cagctggtca
     5701 actttctctt gaccaaggat gtcaaaatga ttgtcattgc ttgtaacact gcgactgcgg
     5761 tcgtctggga agaaatcaag gctcaactag atattcctgt cttgggtgta attttgccag
     5821 gagcttcggc agccatcaag tccagtcaag gtgggaaaat cggagtgatt ggaacgccca
     5881 tgacggtaca atcagacata taccgtcaga aaatccatga tctggatccc gacttacagg
     5941 tggagagctt ggcctgtccc aagtttgctc ccttggttga gtcaggtgcc ctgtcaacca
     6001 gtgttaccaa gaaggtggtc tatgaaaccc tgcgtccctt ggttggaaag gtggatagcc
     6061 tgattttggg ctgtactcat tatccactcc ttcgccctat tatccaaaat gtgatggggc
     6121 caaaggttca gctcatcgat agtggggcag agtgcgtacg ggatatctca gtcttactca
     6181 attattttga aatcaatcgt ggtcgcgatg ctggaccact ccatcaccgt ttttacacaa
     6241 cagccagtag ccaaagtttt gcacaaattg gtgaagaatg gctggaaaaa gagattcatg
     6301 tggagcatgt agaattatga caaataaaat ttatgaatat aaggatgacc aggactggta
     6361 tgttgggtct tatagtattt ttggtggcgt taacagtttg agcgactatc agacagattt
     6421 tcctctgttt gaattctcca aaatatttgg agatgaagag tatggtttcc cgctttcagt
     6481 tactgtttta cgctatggtt ctacctaccg tttgttctcc tttgtggtag acatgcttaa
     6541 tcaagaaatg ggacgaaact tggaagttat tcaacgtcat ggggccctgc tcttggttga
     6601 aaatgggcaa ctcttgtatg tagaattgcc taaagaaggg gtcaatgttc atgatttctt
     6661 tgagacaagc aaggtcagag aaaccttgtt gattgcgact cgtaacgaag gtaaaaccaa
     6721 ggaattccga gctatctttg ataagttagg ctacgatgtg gaaaatctta atgactaccc
     6781 tgacctgcct gaagtagcag aaacaggtat gacctttgaa gaaaatgccc gccttaaggc
     6841 agaaaccatt tctcaattaa cgggcaagat ggttttggca gatgattctg gtctcaaagt
     6901 cgatgtcctt ggtggcttac caggcgtctg gtcagctcgt ttcgcaggtg tgggagcaac
     6961 tgaccgtgaa aataatgcca aactcttgca cgaattggcc atggtctttg aactcaagga
     7021 ccgctcggct cagttccaca caaccctagt cgtagccagc ccaaataagg aaagtttagt
     7081 tgttgaagca gactggtcag gttatattaa ctttgaacct aagggtgaaa atggctttgg
     7141 ctatgatccc ctcttccttg taggagagac aggtgagtca tcagctgaat taaccctgga
     7201 agaaaaaaat agtcaatctc accgtgcctt agccgttaag aaacttttgg aggtatttcc
     7261 atcatggcaa agcaaactat cattgtaatg agcgattccc atggcgatag cttgattgtg
     7321 gaagaagtcc gtgatcgcta tgtgggcaaa gtcgatgccg tttttcataa cggcgattct
     7381 gaactacgtc cgtattctcc actttgggag ggcatccgcg ttgttaaagg gaacatggac
     7441 ttctacgccg gctacccaga acgtctggtg actgagcttg gttcgaccaa gattatccaa
     7501 actcatggtc acttgtttga catcaatttc aactttcaaa agttggacta ctgggctcag
     7561 gaggaagagg ccgctatctg cctctatggt cacttgcatg tgccaagtgc ttggatggaa
     7621 ggcaagatcc tctttctaaa tccaggttct atcagtcaac cacgaggtac catcagagaa
     7681 tgtctctatg ctcgtgtgga gattgatgat agttacttca aagtggactt tttgacacga
     7741 gatcacgagg tgtatccagg tttgtccaag gagtttagcc gatgattgcc aaggagtttg
     7801 agactttctt gttggggcag gaggaaactt ttttgacccc tgctaaaaat ctagctgtgt
     7861 tgattgatac ccacaatgcg gatcatgcga ccctcttgct cagtcagatg acctataccc
     7921 gtgttcccgt tgtgacagat gaaaaacagt ttgttgggac gattggactc agagatatta
     7981 tggcttatca gatggagcat gacttgagcc aagaaatcat ggcggatacg gatatcgttc
     8041 atatgacaaa aacggacgta gcggttgttt cgcctgattt caccattacg gaggtcttgc
     8101 acaagctagt agatgagtcc ttcttaccgg ttgtggatgc agagggtatt ttccaaggga
     8161 ttattacgcg caagtccatc ctcaaggccg ttaatgccct cttgcatgac tttagtaagg
     8221 aatatgagat tcgatgccaa tgagagacag gatttcagcc tttttagagg aaaagcaggg
     8281 cttgtctgtc aattccaagc agtcctataa gtatgatttg gagcaatttt tagacatggt
     8341 aggtgagcgg atttctgaga ccagtctcaa gatttaccaa gcccagctag ccaatctaaa
     8401 aatcagcgcc cagaagcgaa agatttcggc ctgtaaccaa tttctatact ttctctatca
     8461 aaaaggagag gtggacagct tttaccgctt ggaattagcc aaacaagctg aaaagaagac
     8521 ggaaaagcca gagattctat acctagactc tttttggcag gaaagcgacc atccagaggg
     8581 ccgcttgcta gcgctcttaa tcctagaaat ggggctcttg cccagtgaga ttttagccat
     8641 caaggttgcg gacatcaatc tggattttca ggtgttgcga atcagcaagg cttcccaaca
     8701 gaggattgtc accattccca cggccttgct ttcagaattg gaacccttga tggggcagac
     8761 ctatcttttt gaaagaggag agaaacccta ttctcgtcag tgggcctttc gtcagttaga
     8821 atcttttgtc aaggagaaag gttttccatc cttatcagct caagtcttac gtgaacagtt
     8881 tattctaaga caaatagaaa acaaggtcga tttgtacgaa attgcaaaaa aattaggatt
     8941 aaaaacagtc ctgaccttag aaaaatatag ataatggata ttaaattaaa agattttgaa
     9001 ggacccctgg acttgctctt gcatctggtt tctaagtacc agatggatat ctacgatgtg
     9061 cccattacgg aagtcatcga acagtatcta gcctatgtct caaccctgca ggccatgcgt
     9121 ctggaagtga cgggtgagta catggtcatg gctagtcagc tcatgctgat taagagtcgt
     9181 aaactccttc cgaaggtagc agaagtgaca gacttggggg atgacctgga gcaggacctc
     9241 ctctctcaaa tcgaagaata tcgcaagttc aagctcttgg gtgagcactt ggaagccaag
     9301 caccaagaac gggcccagta ttattccaaa gcgccgacag agttgattta cgaagatgcg
     9361 gagcttgtgc atgacaagac gaccattgac ctctttttgg ctttttcaaa tatcctagcc
     9421 aagaaaaaag aggagtttgc acaaaatcac acgacgatct tgcgggatga gtataagatt
     9481 gaggacatga tgattatcgt gaaagagtcc ttggttggac gagctcaatt gcgcttgcag
     9541 gatttgttca aggaagccca gaatgtccaa gaggtcatca ccctcttttt ggcaacccta
     9601 gagttaatca aaacccagga gttgatcctc gtgcaagagg agagttttgg agatatctat
     9661 ctcatggaaa agaaggaaga aagtcaagtg cctcaaagct agacttgata gagaggaaag
     9721 atgagtactt tagcaaaaat agaagcgctc ttgtttgtag cgggtgaaga tgggattcgg
     9781 gtccgccagt tagctgaact cctctctctg ccaccgacag gcatccagca aagtttagga
     9841 aaattagccc agaagtatga aaaggaccca gattccagtt tggctttgat tgagacaagt
     9901 ggtgcttata gattggtgac caagcctcaa tttgcagaga ttttgaagga atactctaag
     9961 gcgcctatca accagagctt gtctcgggct gcccttgaga ccttgtccat tattgcctac
    10021 aaacagccga ttacgcggat agaaattgat gccatccgtg gagttaactc gagtggagcc
    10081 ttggcaaagt tgcaggcttt tgacctgata aaggaagacg ggaaaaagga agtattgggg
    10141 cgccccaacc tctatgtgac tacggattat ttcctagatt acatggggat aaaccattta
    10201 gaagaattac cagtgattga tgagcttgag attcaagccc aagaaagcca attatttggt
    10261 gaaaggatag aagaagatga gaatcaataa gtatattgcc cacgcaggtg tggccagtag
    10321 gagaaaagca gaagagctga ttaagcaagg cttggtgacg gttaacggcc aagtggtgcg
    10381 tgaactagca accactatca agtcaggcga caaggtcgaa gttgaaggtc aacctatcta
    10441 caacgaagaa aaggtctact atctgcttaa caaaccacgc ggtgtgattt ccagtgtgac
    10501 agatgataag ggtcgcaaga cggttgtcga cctcttgccc aatgtcaaag agcgtattta
    10561 ccctgtgggt cgtttggact gggatacatc aggtgtcttg attttgacca atgatgggga
    10621 ctttacagac gagatgattc accctcgtaa tgagattgac aaggtttatg tcgcgcgtgt
    10681 taaaggtgtg gccaataagg acaatctccg ccccttgacc cgtggtcttg agattgatgg
    10741 taagaaaacc aagccagctg tttatgaaat tctcaaagtg gacccagtca aaaatcgctc
    10801 tgtggtgcag ttgaccatcc atgaagggcg taaccatcag gttaaaaaga tgtttgaagc
    10861 tgttggtctc caagtagata agttgtctcg gactcgtttc ggacacctag acttgacagg
    10921 actccgtcca ggagaatccc gtcgtcttaa taaaaaagaa atcagccaac tacacaccat
    10981 ggctgtaact aagaaataat gaaacgaatt ttaatagcgc ctgtgcgctt ttaccaacgt
    11041 tttatctcac cagtctttcc accctcttgt cgctttgagc tgacttgttc caactacatg
    11101 attcaggcta ttgaaaaaca tggttttaag ggggtattga tgggcttggc tcggatttta
    11161 cgttgtcatc cctggtcgaa aacaggtaag gatcccgttc cagaccactt ttcccttaaa
    11221 cgaaatcaag aaggggaatg aggtggggta aatagatttc aaaatgataa aaacgcatcc
    11281 tatcaggttt gagtaaactt gataggatgc gttttagaat gtcaaaattt tatactcttc
    11341 gaaaatctct tcaaaccgcg tcagctttca tctgcaacct caaaacagtg ttttgagcaa
    11401 cctgcggcta gtttcctagt ttgctctttg attttcattg agtattaaat tgagtttgaa
    11461 gtggcttatt tcaaagcttt ttgtatgtct tcaatcatga gttttgttga ttcaagtccg
    11521 cctccgctta gataccagag gtctggtgtt agttggataa tcttaccatt tttagcagca
    11581 ggtgtttcag cgataagggc attttctagg acaccgtcgt tgctagagtt gtccccaccg
    11641 atggcaaggg tacggttgat gacaaagagg atgtcagggt tgatttcttt gacactttca
    11701 aagctgactt cttgtccgtg gcgtgagtct tcaaattttg tatcagttgg tttgaatttc
    11761 aaggtttggt acaagaaaga gaaacgagat ttggcaccaa aggctgccat ttttccttca
    11821 ttaaggagga tcgcaagggc ttttttgtca gagctttcat ttttagtagc gacttcttgg
    11881 atgctcttgt ctagcttggc caattcttcc ttggctttct gtgtaccagt ttcgccgaag
    11941 gcacttgcta aggattcgat attagccttg gtagaagtcc agtagtcatc cttgcttgct
    12001 tggaagagaa cggttggggc gatttctttg aatttgtcta cgaatttttg tgtacgtggt
    12061 gaagcgataa tcaaatcagg ctcaagggcg gcgatagctt ctaaatcagg ttctttcata
    12121 gaaccaacat ttttgacagt tcccactagg tcttttagat aagtcggaac agtttttgta
    12181 ggcattccga cgatattttt ttcaaatcct aaagcgcgaa tagtatccgc agcgccgagg
    12241 tcaaaggtca caatcttttc aggaactttg gaaagtttga cctcgtccag tgaactttta
    12301 atggttatct ctgttggagc agagctactg gtctctgtct gactagtgct tgagtttgta
    12361 ctacatgcac caagtaggag caagaagctg gccactaggg cagtgaaata aagtttaagg
    12421 gatgttttca taatttctcc tttttaaaat gtgataacga tttagggagt ctcttaatct
    12481 tattgactaa gagactgaag gttctctaac ttgagctttt atgttactag ctatagatac
    12541 agatcttttt gtcattgata tcagctagcg tgatgggaat ctcataaagt tgactgagca
    12601 ggtcagcctg catgatttga tcggttcttc ccttgctaaa gacctggccg tccttgaagg
    12661 cgacaatttc atctgcatac tgactggcca tgttgatatc gtggaggacg atgataatgg
    12721 tcttgccgag ttcctccacc agtcgtcgaa gaatctgcat catgctgacg ctttgcttga
    12781 tatcgagatt gttgagtggt tcgtccagca agataaagtc cgtatcctgg gccagtacca
    12841 tagcgataaa gacgcgctgg agttgccccc ctgacaggct attgatgtag cggtctttta
    12901 agttggtcag ttccaaatag ttcagagttt ctcggatttt ttcccagtct tctgatctaa
    12961 gtcgacctcg gctgtaggga aaacgtccaa aactgaccag ttcttcaaca gtcaatttgg
    13021 cttggtaatt gattttctgt tttaggatgg ttagttcttg ggccagttct tgcgaattcc
    13081 agctctcgat ttcacgtcct ttgatactga gaactccctg atctttcttg gttagtctgc
    13141 tcatgatgga gaggagagtc gattttccag caccatttgg accaataaag gctgtcagtt
    13201 tttgaggact gacttcaagc gaaatgcctt gcaaaatatc ctgtttttga atggatttgt
    13261 caatgttttc cagtttcact gacgagccct cctatatagt aagataaaga ataagaagcc
    13321 acccacactc tcaatgatca tactgatacg aatttccagt gcaaagactc gttcaatcaa
    13381 ggcttgcccc aaggttaagc taataaatcc aaccagaatg gccactataa agagtaactt
    13441 gtgctgatag tctttgacaa tcaggtaggt gaggttggcc agcataaagc cgaagaaggc
    13501 cataggtcct accaaggcag tggccgttga ggtcaaaagc acgattcccc agaggagctc
    13561 tttctgttct ttttcaacat cgagtcccaa tatctgagcc gtttctcttt gcaggtgcaa
    13621 gacatctaga acgactgctt ttcgaaagaa aaagattgtc aaagcgagga tgatcagaga
    13681 accgatggct aggatggaag tgttaagatg ttgaaaggag gcaaaaagac tattttgcag
    13741 tttatcgtat tcgtttggat ccattaggac ttgaaggaag gtgctgatat ttcgaaagag
    13801 acttctgagc gctagacaga tcagcaggat gaagaccagg tcttgcttca tcagtgtctt
    13861 caagtaacct tgtaaggcga gaaagaagaa ggactggaca agaagtaaga ctaggaattc
    13921 taagataggg gatttgccaa gttgaagaaa cttgctttca aaaaccagta gtagggtttg
    13981 tagtaggacg tagaaggatt caattcccaa aatactaggc gtcaggaagc gattttccgt
    14041 cagggtttga aaactaatgg tcgaaatccc agtcgcgatg gctaccaaga gataaacgat
    14101 gatcttttgg gaacgcaact tccaagcaaa ggctgacaag tgagtgatgg gccaaaagta
    14161 gagaagacaa gctccgatgg caagaataat gagaatccag aagagcttgg tatgtttgct
    14221 tttagtctgc atcttttcgt ccccctctcc agagaagtag gataaagacg agactaccga
    14281 tgattcctag caagagactg acagacaact catagggcct aatcagaact cgggatagga
    14341 tatcgcaagc cagaactaga ttggcaccaa ccagtgcgac catgagtttg gtttgactta
    14401 gattatctcc atagcgcttg cgaacaagat tgggaacgat aactccgaga aatggtaagc
    14461 cacccacggt aatcatggtg acgcttgtcg ttagcgccac cagaaagagg gccagttttt
    14521 caagtaggga gtaggaaatc cccaaactct cgctggtttc tttccctaga ttcatgatgg
    14581 tgaaggtttg ggataatttc caaacggtta tcaggatgat gaggcctaag aagagccact
    14641 catactgatg ggtctgaatc atggagaagg agccctgggt ccaggcagtc atactctgaa
    14701 ccagattgaa acgataggcg ataacttctg tgactgagcc gataatcccg ctatagatga
    14761 tcccaatcag aggcaacatc cacctttcct ttacagtaaa aatggtcata aaggctagga
    14821 agaagagggt gaatagaatg gatgaaacaa aagcgaagag catcttttgg gtcagactag
    14881 ccgatggaaa gacaaaaagg ctcagcacca ttcccagttt ggcggcttca gtcgttccaa
    14941 ctgtactcgg tgcagcaaac tgattttggg taatagtctg catgagaagg cctgccatac
    15001 tcatactaga ggcagtcagg agaatactga tagttcttgg gagacgggac tcttgaaaga
    15061 ggagccaggt ctgctggtcg aaatcaaata gctttcccca tgaaaaatca ctggtcccaa
    15121 tgctaataga gagaaagact aggagtagaa gtaagccaat taaataatga gaaagtttca
    15181 taccccgtcc tttcatgtag atttggtatc gaaagatacc tgcggatata aatgtaacat
    15241 tatttttcta atctgtcaat aaaatttctg acaatttaat aaatacaaca aggagagagc
    15301 aacaagactt tctcctttgt tatcctattc taaaatgttt ttaccttaat ctgataaaat
    15361 aatatcttcg agggagtagc tagccgtcca atcaagatat tgtttagctt ttgaagcatc
    15421 tgctaggaca ctggctgggt cactagcacg tcgagcaaca atctcgtgtg ggatttttta
    15481 atttagtaat tcttcagcag ttttaaagat ttctttgata gtatagcctt ttttagttcc
    15541 taagttaaag atttgagaag aactgtcttc ttgaaatagg tagttcattc ctttaacatg
    15601 agcctatgca aggtccaaga cataaatgta atctcgaata catgaaccgt cacgtgtatc
    15661 gtagtcatct ccaaatattt ttaagctatc attttgtccc aatgcggtct tgttgatatt
    15721 tggaatgatg tgagttggat ttttcacacg cagaccgttt gaagcatcca tttcagcccc
    15781 agcaacatta aagtaacgga aaataacata tttccagtcg tagcgattgg ccatccagta
    15841 aatcattcgt tcgcccatca gttttgtctc tgcataaggg ttgacagggt cgagcagggt
    15901 atcttcagtc accggcttgt caatacagtt atttccatag agagaagcag tcgaagagaa
    15961 catgattttt tgaatgccaa cttcagataa gactttgaga acttggttca taccagcaac
    16021 gttggcagtg aagtatttac ttggattttc aatactttcg ctcacaacaa tttcacctgc
    16081 acaatggagg acagcatcaa tctgattttc ttctaagtaa gcctttaagg cgctagcatc
    16141 ataaacatcc agttctttaa agctagcacg actatccaca gccgctcgat ttcctgtgga
    16201 gagattatcg aggacatgca cctgatagcc agcatttaaa agagctttaa cggtatggga
    16261 gccaatgtag ctagtcccac ctgtaacaag aattgttttg gtcatgattt tttccttttc
    16321 tagttttgta ctatagtaa
//
LOCUS       DAVMCN010000038        16170 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVMCN010000038 DAVMCN010000000
VERSION     DAVMCN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.038"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..999
                     /gene="lytB"
                     /locus_tag="VYP85_001459"
     CDS             <1..999
                     /gene="lytB"
                     /locus_tag="VYP85_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1881954.1"
                     /translation="WFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQL
                     GSDGKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRL
                     AITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVG
                     KKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFK
                     EAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKG
                     ILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1060..2715)
                     /gene="pavA"
                     /locus_tag="VYP85_001460"
     CDS             complement(1060..2715)
                     /gene="pavA"
                     /locus_tag="VYP85_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1881955.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKITSMKKS"
     gene            2820..3317
                     /gene="ybeY"
                     /locus_tag="VYP85_001461"
     CDS             2820..3317
                     /gene="ybeY"
                     /locus_tag="VYP85_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1881956.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3298..3693
                     /locus_tag="VYP85_001462"
     CDS             3298..3693
                     /locus_tag="VYP85_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1881957.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3710..4609
                     /gene="era"
                     /locus_tag="VYP85_001463"
     CDS             3710..4609
                     /gene="era"
                     /locus_tag="VYP85_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1881958.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4658..5482
                     /gene="mutM"
                     /locus_tag="VYP85_001464"
     CDS             4658..5482
                     /gene="mutM"
                     /locus_tag="VYP85_001464"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1881959.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5482..6087
                     /locus_tag="VYP85_001465"
     CDS             5482..6087
                     /locus_tag="VYP85_001465"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1881960.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFEQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6074..7273
                     /locus_tag="VYP85_001466"
     CDS             6074..7273
                     /locus_tag="VYP85_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1881961.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7273..7422
                     /gene="rpmG"
                     /locus_tag="VYP85_001467"
     CDS             7273..7422
                     /gene="rpmG"
                     /locus_tag="VYP85_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1881962.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7462..7695
                     /gene="secG"
                     /locus_tag="VYP85_001468"
     CDS             7462..7695
                     /gene="secG"
                     /locus_tag="VYP85_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1881963.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7797..10151
                     /gene="rnr"
                     /locus_tag="VYP85_001469"
     CDS             7797..10151
                     /gene="rnr"
                     /locus_tag="VYP85_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1881964.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQTLGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10114..10581
                     /gene="smpB"
                     /locus_tag="VYP85_001470"
     CDS             10114..10581
                     /gene="smpB"
                     /locus_tag="VYP85_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1881965.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10597..11457
                     /gene="tehB"
                     /locus_tag="VYP85_001471"
     CDS             10597..11457
                     /gene="tehB"
                     /locus_tag="VYP85_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1881966.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11530..12483
                     /gene="coiA"
                     /locus_tag="VYP85_001472"
     CDS             11530..12483
                     /gene="coiA"
                     /locus_tag="VYP85_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1881967.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12502..14304
                     /gene="pepF"
                     /locus_tag="VYP85_001473"
     CDS             12502..14304
                     /gene="pepF"
                     /locus_tag="VYP85_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1881968.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14306..15019
                     /locus_tag="VYP85_001474"
     CDS             14306..15019
                     /locus_tag="VYP85_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1881969.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            15086..16027
                     /gene="prsA"
                     /locus_tag="VYP85_001475"
     CDS             15086..16027
                     /gene="prsA"
                     /locus_tag="VYP85_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1881970.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
BASE COUNT         4873 a         3025 c         3644 g         4628 t
ORIGIN      
        1 tggttttacc tcaagtctga tggtaaaatg gctgaaaaag aatgggtcta cgattctcat
       61 agtcaagcct ggtactactt caaatctggt ggctacatgg cgaaaaatga gacagtagat
      121 ggttatcagc ttggaagcga tggtaaatgg cttggaggaa aaactacaaa tgaaaatgct
      181 gcttactatc aagtagtgcc tgttacagcc aatgtttatg attcagatgg tgaaaagctt
      241 tcctatatat cgcaaggtag tgtcgtatgg ctagataagg atagaaaaag tgatgacaag
      301 cgcttggcta ttactatttc tggtttgtca ggctatatga aaacagaaga tttacaagcg
      361 ctagatgcta gtaaggactt tatcccttat tatgagagtg atggccaccg tttttatcac
      421 tatgtggctc agaatgctag tatcccagta gcttctcatc tttctgatat ggaagtaggc
      481 aagaaatatt attcggcaga tggcctgcat tttgatggtt ttaagcttga gaatcccttc
      541 cttttcaaag atttaacaga ggctacaaac tacagtgctg aagaattgga taaggtattt
      601 agtttgctaa acattaacaa tagccttttg gagaacaagg gcgctacttt taaggaagcc
      661 gaagaacatt accatatcaa tgctctttat ctccttgccc atagtgccct agaaagtaac
      721 tggggaagaa gtaaaattgc caaagataag aataatttct ttggcattac agcctatgat
      781 acgacccctt acctttctgc taagacattt gatgatgtgg ataagggaat tttaggtgca
      841 accaagtgga ttaaggaaaa ttatatcgat aggggaagaa ctttccttgg aaacaaggct
      901 tctggtatga atgtggaata tgcttcagac ccttattggg gcgaaaaaat tgctagtgtg
      961 atgatgaaaa tcaatgagaa gctaggtggc aaagattagt actataagtg aatatgattt
     1021 gagtgaatag taagttaaaa atcctgattt caagtaaaat caggattttt tcatggatgt
     1081 aatttttttg gagtctggtg tgacgcggag ggtcttttgt cctgtgtaag tgacaaagcc
     1141 gggttttcca ccagttggtt tattgagttt tttgacttca atcatatcta cctgcaccag
     1201 attcgacagg cgcccttgag agaagtaggc agctaactct gctgcgtctg tcttgactgc
     1261 atcagatggg tcaagatttc ctgagatgac aacatggctt ccaggaatgt ccttagcatg
     1321 gaaccaaagt tcctccttgc gggccatttt aaaggtcaat tcctcatttt gaagattgtt
     1381 tcgtccgaca tagatgatgg ttttgccatc gcttgctaga tattgttcta gttttttgcg
     1441 tttctggatt ttctcccgtt gtcttctgcg gataaaacct gtttgaatca attcttcacg
     1501 gatttcagcg atttcttcca gtccagcttg gttgaggacg gtttctacac tttccagata
     1561 gagaatagtg gctttggttt cttcaatcaa atcagtcaag tatttgacag cttctttgag
     1621 tttctgatac cgtttaaaat agcgttgggc attctggttg ggagtcagag ccttatcaag
     1681 cgcaatcatg ataggttggt tggtatagta gttgtctagg ataacctggt cttggtcgtt
     1741 aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt tgacgaaatt cttcagcgtt
     1801 gtctgtcgcc agtaattctt tttcctgttt tttgagtttg tgtcggtttt tctgaagttc
     1861 attttcaaca cgacgaatca gttcactggc ctgctgtttg acgcggtcgc gctcagcctt
     1921 atccttatag taggtgtcca acaaatcaga aagatttgca aaaggctctc ccacctgatt
     1981 tgcaaaagga actggactga aggaagtctc agtcaagcat ggcttggttt cctgattgaa
     2041 aaaatttcgg aaagcggaaa gtttttcact aaccagtatc ctttccaatt catttgccgt
     2101 atcgcgtccc agaccttgaa agaggctttg aagatttttt gctgttagtt cttgggtttg
     2161 caggatttca aagagctttt catccttgat agtaaaagga ttgagagatt ctgtacttgg
     2221 cggagcgata taggtcgatc ctggaagtaa ggtgcggtag ctattttgtg aaaagccgac
     2281 gtgtttgata acttcgagga ttttatgact gcttttatcg accagtagaa tattactgtg
     2341 tttccccata atttcgataa tcaaggtagc ctggatatgg tctccaatct cgtttttatt
     2401 ggaaactgtc atttccacaa tacggtcatt ttccacttgc tcaatcgact caatcagggc
     2461 cccctgcaaa tactttctca aaaccatgat aaaggtagaa ggttgggctg gattttcaaa
     2521 agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg gcagaaagga gcaggcgatg
     2581 gctttggcga ttgctgcgga tttgcaagac caactcttgt tcaaaaggct gattgatttt
     2641 ctggatgcga ccattcacta attcgcttcg caattcctca actatgtggt gtaaaaaaaa
     2701 tccgtcaaat gacatcgttc tctccttgtg attgtattcc atagtattat atcaaaaagg
     2761 tagaataaaa tcatggaaat gtggtataat aaagccaagt aaagagaaac gagaagcaca
     2821 tgtatattga aatggtagat gaaactggtc aagtttcaaa agaaatgttg caacaaaccc
     2881 aagaaatttt ggaatttgca gccaaaaaat taggaaaaga agacaaggag atggcagtca
     2941 cttttgtgac caatgagcgt agtcatgaac ttaatctgga gtaccgtgac accgaccgtc
     3001 cgacagatgt catcagcctt gagtataaac cagaattgga aattgccttt gacgaagagg
     3061 atttgcttga aaatccagaa ttggcagaga tgatgtctga gtttgatgcc tatattgggg
     3121 aattgttcat ctctatcgat aaggctcatg agcaggccga agaatatggt cacagctttg
     3181 agcgtgagat gggcttcttg gcagtacacg gctttttaca tattaacggc tatgatcact
     3241 atactccgga agaagaagcg gagatgttcg gtttacaaga agaaattttg acagcctatg
     3301 gactcacaag acaataaacg aaaatggaaa aatcgtgacc tgatatccag tttagaattt
     3361 gccatcacag ggatttttac tgctatcaag gaagaacgca atatgcgaaa acatgcagtg
     3421 acggctctag tggtcatcct tgcaggtttt ggttttcagg tgtcacgaat cgaatggctc
     3481 tttctcctat tgagcatttt cttggtggta gcctttgaaa ttatcaattc tgctattgaa
     3541 aatgtggtgg atttggccag tcactatcac ttttccatgc tggctaaaaa tgccaaggat
     3601 atggcggctg gcgcggtatt agtggtttct ctttttgcag ccttaacagg cgcattgatt
     3661 tttctcccac gaatctggga tttattattt taaacagtaa gaggaaatta tgacttttaa
     3721 atcaggcttt gtagccattt taggacgtcc caatgttggg aagtcaacct ttttaaatca
     3781 cgttatgggg caaaagattg ccatcatgag tgacaaggcg cagacaacgc gcaataaaat
     3841 catgggaatt tacacgactg ataaggagca aattgtcttt atcgacacac cagggattca
     3901 caaacctaaa acagctctcg gagatttcat ggttgagtct gcctacagta cccttcgcga
     3961 agtggacact gttcttttca tggtgcctgc tgatgaagcg cgtggtaagg gggacgatat
     4021 gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt ttggtggtga ataaaatcga
     4081 taaggtccat ccagaccagc tcttgtctca gattgatgac ttccgtaatc aaatggactt
     4141 taaggaaatt gttccaatct cagcccttca gggaaataac gtgtctcgtc tagtggatat
     4201 tttgagtgaa aatctggatg aaggtttcca atatttcccg tctgatcaaa tcacagacca
     4261 tccagaacgt ttcttggttt cagaaatggt tcgcgagaaa gtcttgcact taactcgtga
     4321 agagattccg cattctgtag cagtagttgt tgactctatg aaacgagacg aagagacaga
     4381 caaggttcac atccgtgcaa ccatcatggt cgagcgcgat agccaaaaag ggattatcat
     4441 cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg gcccgtcgtg atatcgaact
     4501 catgctagga gacaaggtct tcctagaaac ctgggtcaag gtcaagaaaa actggcgcga
     4561 taaaaagcta gatttggctg actttggcta taatgaaaga gaatactaag tagaggtagg
     4621 ctcatgcctg cttcttgttt ttacagaagg aggacttatg cctgaattac ctgaggttga
     4681 aaccgtttgt cgtggcttag aaaaattgat tataggaaag aagatttcga gtatagaaat
     4741 tcgctacccc aagatgatta agacggattt ggaagagttt caaagggaat tgcctagtca
     4801 gattatcgag tcaatgggac gtcgtggaaa atatttgctt ttttatctga cagacaaggt
     4861 cttgatttcc catttgcgga tggagggcaa gtatttttac tatccagacc aaggacctga
     4921 acgcaagcat gcccatgttt tctttcattt tgaagatggt ggcacgcttg tttatgagga
     4981 tgttcgcaag tttggaacca tggaactctt ggtgcctgac cttttagacg cctactttat
     5041 ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt gatttacagg tctttcaatc
     5101 tgcccttgcc aagtccaaaa agcctatcaa atcccatctc ctagaccaga ccttggtagc
     5161 tggacttggg aatatctatg tggatgaggt tctctggcga gctcaggttc atccagctag
     5221 accttcccag actttgacag cagaagaagc gacagctatt catgaccaaa ccattgctgt
     5281 tttgagccag gctgttgaaa aaggcggttc caccattcgg acctatacca atgcctttgg
     5341 ggaagatgga agcatgcagg attttcatca ggtctatgat aagactggtc aaggatgtgt
     5401 acgctgtggt accatcattg agaaaattca actaggcgga cgaggcaccc acttttgtcc
     5461 aaactgtcaa aggagggact gatgggaaaa atcatcggaa tcactggggg aattgcctct
     5521 ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct ttcaagtagt ggatgccgac
     5581 gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt ttgaggctct agtacagcac
     5641 tttgagcaag aaatcattct tgaaaacgga gaactcaatc gccctctcct agctagtctc
     5701 atcttttcaa atcctgaaga gcaaaaatgg tcgaagcaaa ttcaagggga gattatccgt
     5761 gaggaactgg ctactttgag agaacagttg gctcagacag aagagatttt cttcatggat
     5821 attcccctac tttttgagca ggactacagc gattggtttg ctgagacttg gttggtctat
     5881 gtggaccgag atgcccaagt agaacgctta atgaaaaggg accagttgtc caaagatgaa
     5941 gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa agaaagattt ggccagccag
     6001 gttcttgata ataatggcaa tcagaaccag cttcttaatc aagtgcatat ccttcttgag
     6061 ggaggtaggc aagatgacag agattaactg gaaggataat ctgcgcattg cctggtttgg
     6121 taattttctg acaggagcca gtatttcttt ggttgtacct tttatgccca tcttcgtgga
     6181 aaatctaggt gtagggagtg agcaagtcgc tttttatgca ggcttagcaa tttctgtctc
     6241 tgctatttcc gcggcgctct tttctcctat ttggggtatt cttgctgaca aatacggccg
     6301 aaaacccatg atgattcggg caggtcttgc tatgactatc actatgggag gcttggcctt
     6361 tgtcccaaat atctattggt taatctttct tcgtttacta aacggtgtat ttgcaggttt
     6421 tgttcctaat gcaacggcac tgatagccag tcaggttcca aaggagaaat caggctctgc
     6481 cttaggtact ttgtctacag gcgtagttgc aggtactcta actggtccct ttattggtgg
     6541 ctttatcgca gaattatttg gcattcgtac agttttctta ctggttggta gttttctatt
     6601 tttagctgct attttgacta tttgctttat caaggaagat tttcaaccag tagccaagga
     6661 aaaggctatt ccaacaaagg aattatttac ctcggttaaa tatccctatc ttttgctcaa
     6721 tctcttttta accagttttg tcatccaatt ttcagctcaa tcgatcggcc ctattttggc
     6781 tctttatgta cgcgacttag ggcagacaga gaatcttctt tttgtctctg gtttgattgt
     6841 gtccagtatg ggcttttcca gtatgatgag tgcaggagtc atgggcaagc taggtgacaa
     6901 ggtgggcaat catcgtctct tggttgtcgc ccagttttat tcagtcatca tctatctcct
     6961 ctgtgccaat gcttctagcc cccttcaact aggactctat cgtttcctct ttggcttggg
     7021 aaccggtgcc ttgattcccg gggttaatgc cctactcagc aaaatgactc ccaaagccgg
     7081 catttcgagg gtctttgcct tcaatcaggt attcttttat ctgggaggtg ttgttggtcc
     7141 catggcaggt tctgcagtag caggtcaatt tggctaccat gctgtctttt atgcgacaag
     7201 cctttgtgtt gcctttagtt gtctctttaa cctgattcaa tttcgaacat tattaaaagt
     7261 aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct cctcttgtga cagtatcaat
     7321 tacctaacca gtaaaaattc aaaaacccat ccagacaaga ttgaggtttt aaagtattgt
     7381 cccaaggaaa gaaaagtaac cctacatctt gaatctaagt agattttatg gtaaaataat
     7441 agggatttta aggagtttga tatgtataac ctattattaa ccattttatt agtattatct
     7501 gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa accaatccag caatgtattt
     7561 gatgccagtt caggtgattt gtttgaacgc agtaaagctc gcggttttga agctgtaatg
     7621 cagcgtttga cagggatttt agtctttttc tggctagcca ttgccttagc attgacggta
     7681 ttatcaagta gataagaaaa taatgggcag gactaggtct ttgcctcttt ttatttttaa
     7741 aggatgtttg agaaggtttt acagtaaaag aaaattaaaa aatctagaaa gaaaatatga
     7801 aagatagaat aaaagaatat ttacaagaca agggaaaggt gactgttaat gatttggctc
     7861 agactttggg aaaagacagt tccaaggatt ttcgtgagtt gattaaaacc ttgtccttaa
     7921 tggaaagaaa gcaccagatt cgctttgaag aagatggtag tctgacatta gaaattaaga
     7981 aaaaacatga gattaccctc aaggggattt ttcatgccca taaaaatggc tttggctttg
     8041 ttagtctgga aggcgaggag gacgaccttt ttgtagggaa aaatgatgtc aactatgcta
     8101 ttgatggtga taccgtcgag gtagtgatta agaaagtcgc tgaccgcaat aagggaacag
     8161 cagcagaagc caaaattatt gatatcctag aacacagttt gacaacagtt gtcgggcaaa
     8221 tcgttctgga tcaggaaaaa cctaagtatg ctggctatat tcgttcaaaa aatcagaaaa
     8281 tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt agaaggaaca gaagttctca
     8341 aagtctttat cgataaatac ccaagcaaga aacatgattt ctttgtcgcg agtgttctcg
     8401 atgtggtggg acactcaacg gatgtcggaa ttgatgttct tgaggttttg gaatcaatgg
     8461 acattgtatc cgagtttcca gaagctgttg ttaaggaagc agaaagtgtg cctgatgctc
     8521 cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga tgaaattacc tttaccattg
     8581 acggtgcgga tgccaaggac ttggacgatg cagtgcatat caaggctctg aaaaatggca
     8641 atctggagct tggggttcac atcgcagatg tttcttatta tgtgaccgag gggtctgccc
     8701 ttgacaagga agcccttaac cgtgcgactt ctgtttacgt gacagaccga gtggtgccaa
     8761 tgcttccaga acgactatca aatggcatct gctctctcaa tccccaagtt gaccgcctga
     8821 cccagtctgc tattatggag attgataaac atggtcgtgt ggtcaactat accattacac
     8881 aaacagttat caagaccagt tttcgtatga cctatagcga tgtcaatgat atcctagctg
     8941 gcgatgaaga aaagagaaaa aaatatcata aaattgtacc aagtatcgaa ctcatggcca
     9001 agcttcatga aactttagaa aacatgcgtg tgaaacgtgg agctctcaat tttgatacca
     9061 atgaagcgaa gattttagtg gataaacaag gtaagcctgt tgatatcgtt cttcggcagc
     9121 gtggtattgc cgagcggatg attgagtctt ttatgttgat ggctaatgaa acagttgccg
     9181 aacatttcag caagttggat ttgcctttta tctatcgaat tcacgaggag cctaaggctg
     9241 aaaaggttca gaagtttatt gattatgctt cgagttttgg cttgcgcatt tatgggactg
     9301 ccagtgagat tagtcaggag gcacttcaag acatcatgcg tgctgttgag ggagaatctt
     9361 atgcagatgt attgtccatg atgcttcttc gctctatgca gcaggctcgt tattcggagc
     9421 acaatcacgg ccactatgga ctagctgctg actattatac tcactttacc agtccaattc
     9481 gtcgttatcc agaccttctt gttcaccgta tgattcggga ttacggccgt tctaaggaaa
     9541 tagcagagca ttttgaacaa gtgattccag agattgcgac ccagtcttcc aaccgtgaac
     9601 gtcgtgccat agaagctgaa cgtgaagtcg aagccatgaa aaaggctgag tatatggaag
     9661 aatacgtggg tgaagagtat gatgcagttg tatcaagtat tgtcaaattc ggtctctttg
     9721 tcgaattgcc aaacacagtt gaaggcttga ttcacatcac taatctacct gaattttatc
     9781 atttcaatga gcgtgatttg actcttcgtg gagaaaaatc aggtatcact ttccgagtgg
     9841 gtcagcagat ccgtatccgt gttgaaagag cggataaaat gactggagag attgattttt
     9901 cattcgtacc tagtgagttt gatgtgattg aaaaaggctt gaaacagtct agtcgtagtg
     9961 gcagagggcg tggttcaaat cgtcgttcgg ataagaagga agacaagaga aaatcaggac
    10021 gctcaaatga taagcgtaag cattcacaaa aagacaagaa gaaaaaagga aagaaacctt
    10081 tttacaagga agtagctaag aaaggagcca agcatggcaa agggcgaggg aaaggtcgtc
    10141 gcacaaaata aaaaggcacg ccacgactat acaatcgtag atacgctaga ggcagggatg
    10201 gtcctgactg gaactgaaat caagagtgta cgagctgctc gaattaatct caaggatggc
    10261 tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg ttcatatcgc gccttacgaa
    10321 gagggcaata tctggaacca ggaaccagaa cgtcgtcgta aactcctgct ccataaaaag
    10381 caaattcaaa aattggaaca agagaccaaa gggacaggaa tgaccttagt tccccttaag
    10441 gtctatataa aagatggcta cgctaagctt cttttaggac ttgccaaagg gaagcatgac
    10501 tatgacaaac gggagtctat caaacgtcgt gagcaaaatc gagatatcgc gcgtgtgatg
    10561 aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg aaaaattagt tgcctataaa
    10621 cgcatgcctt tgtggaataa acaaacaatg cctgaagctg ttcagcaaaa gcacaataca
    10681 aaagttggga cttgggggaa aattactgtc ttgaagggag ctctcaagtt tattgaattg
    10741 acagaagaag gagaagttct agctgaacac ctctttgaag caggggcaga caatccaatg
    10801 gcccaacctc aagcctggca ccgagtggaa gctgccacag atgatgtgga atggtacttg
    10861 gaattttatt gtaagcctga ggattatttt gctaaaaaat acaataccaa tcctgttcat
    10921 tcagaggtcc tagaggccat gcagacagtg aaacaaggga aagctttgga tttgggttgt
    10981 ggtcaggggc gtaattctct ttttctagcc cagcaagatt ttgatgtgac ggctgtagat
    11041 caaaatggac tggctcttga aatcttgcaa agcattgtgg agcaggaaga tttggacatg
    11101 cctgttggcc tttacgatat caattcagct agcattggac aagaatatga ttttatcgtt
    11161 tcaacagttg ttctcatgtt tctacaagcg gaccgcattc cagctattat tcaaaatatg
    11221 caggagaaaa ccagtgttgg tggttacaac cttatcgttt gtgccatgga cacggaggat
    11281 tatccttgct cggttaattt cccattcacc tttaaagaag gagaactggc agactattac
    11341 aaggattggg aattggttaa gtacaatgaa aatccaggcc atttgcaccg tcgcgatgag
    11401 aatggtaatc gtattcaact acgctttgcg accttactag ctaagaaaat caagtaaaca
    11461 cacatgaaga ttaggaattt tcctgatctt ttttcttttt tacgaatgat atagaaaagg
    11521 agggaattca tgtttgttgc gagagatgct aggggagaat tggtaaatgt gttagaggat
    11581 aaacttgaga agcaagcata cacctgccca gcttgtggag gccagctcca tttgcgtcaa
    11641 ggaccaagtg tacggacgca ttttgcccat aaatccttaa aagactgtga ttttttcttt
    11701 gaaaatgaaa gtccagaaca cctggccaat aaggaatccc tctatcactg gttgaaaaaa
    11761 gagacaaagg ttcaattaga gtacccgctt tcagaactta aacagattgc ggatgtattt
    11821 gtaaatggca atctagctct agaagttcag tgtagtccct tgcctcagaa agtccttaaa
    11881 gagcgaagtg agggatatcg tagtcagggt taccaagtac tgtggttgct gggtcaaaaa
    11941 ctgtggctca aggagcgttt gactcgtcta cagcaaggtt ttctttattt cagtcaaaac
    12001 atgggctttt atgtttggga attagacaag gaaaaacaag ttttaagact caaatacctg
    12061 atttaccagg atctccgcgg taaactccat tatcaaatca aggaattttc ctatggtcaa
    12121 ggtagtttat tggaaatatt gcgtcttccc tataagagac aaaaaatatc tcattttaca
    12181 gtttctgagg acaaggacat ctgtcgctat atccggcaac aactttatta tcaaaatctc
    12241 ttttggatga aagaacaagc agaagcctat caaaagggag aaaatatcct gacttatgga
    12301 ctgaaagaat ggtatccaca aattcgacca atagtgggca aatttttcca gattgaacaa
    12361 gacttgacta gctattatca gcacttttat acctattacc aaaaaaatcc tcaaaatgat
    12421 tggcaaaagc tttatccacc agccttttat cagcaatatt tcttgaaaaa tatggtagaa
    12481 tagaaaggat ggaggaatct aatggtatta caaagaaatg aaataaatga aaaagataca
    12541 tgggatctat caacgatcta cccaactgac caggcttggg aagaagcctt aaaagattta
    12601 acagaacaat tggagacagt agcccagtat gaaggccatc tcttggatag tgcggataac
    12661 ctactagaaa tcactgaatt ttctcttgaa atggaacgcc agatggagaa gctttacgtt
    12721 tatgctcata tgaagaatga ccaggataca cgtgaagcta agtatcaaga gtactatgcc
    12781 aaggccatga cactctacag ccagttagac caagcctttt cattctatga gcctgaattt
    12841 atggagatta gcgaaaagca gtatgctgac tttttagaag ctcaaccaaa gctgcaggtt
    12901 tatcaacact attttgacaa gctcttgcaa ggcaaggatc acgttctttc acaacgtgaa
    12961 gaagaattat tggctggagc tggagaaatc tttggttcag caagtgaaac cttcgctatc
    13021 ttggacaatg cggatattgt gttcccttat gtcctagacg atgatggtaa agaagttcag
    13081 ctatctcatg ggacttacac acgtttgatg gagtctaaaa aacgtgaggt tcgccgtggt
    13141 gcctatcaag ctctttatgc gacttacgaa caattccaac acacctatgc caaaactttg
    13201 caaaccaatg ttaaggtgca aaattaccgt gctaaagttc gtaactacaa gagtgctcgt
    13261 catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt atgacaattt ggtagcagca
    13321 gttcgcaagc atttgccact cttacatcgc tatcttgagc ttcgttcaaa aatcttgggg
    13381 atttcagatc tcaagatgta cgatgtctac acaccgcttt catctgttga atacagtttt
    13441 acctaccaag aagccttgaa aaaagcagaa gatgctttgg tagtcttggg tgaggattac
    13501 ttgagccgtg ttaaacgtgc cttcagcgag cgttggattg atgtttacga aaatcaaggc
    13561 aagcgttcag gtgcctactc tggtggttct tacgatacca atgcctttat gcttctcaac
    13621 tggcaggaca atctggacaa tctctttact cttgttcatg aaacaggtca cagtatgcat
    13681 tcaagctata ctcgtgaaac tcagccttat gtttacggag attactctat ctttttggct
    13741 gagattgcct caactaccaa tgaaaatatc ttgacggaga aattattgga agaagtggaa
    13801 gacgacgcaa cacgctttgc tattctcaat aacttcctag atggtttccg tggaacagtt
    13861 ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc accaagcaga tcaaaatggg
    13921 gaggtcttga caagcgattt cctaaataaa ctctacgcag acttgaacca agagtattat
    13981 ggtttgagta aggaagacaa tcctgaaatc caatacgagt gggctcgcat tccacacttc
    14041 tactataact actatgtata tcaatattca actggctttg cggccgcctc agccttggct
    14101 gaaaaaattg tccatggtag tcaagaagac cgtgaccgct atatcgacta cctcaaggca
    14161 ggtaagtcgg actatccact taatgtcatg agaaaagctg gtgttgatat ggagaaggaa
    14221 gactacctca acgatgcctt tgcagtcttt gaacgccgtt taaatgagtt tgaagccctt
    14281 gttgaaaaat taggattggc ataaaatggt tgaatcgtat agtaagaatg ctaaccataa
    14341 catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg atgcgtcagc gtcaaaagca
    14401 ggtcacaggt ttcttgaaag aattggaaga ctttgcccgc aaggaaaata ttcctattat
    14461 tccccatgaa acggttgctt atttccgttt tcttatggaa accatgcagc ctaaaaatat
    14521 tctggaaatt gggacggcta tcggtttttc agctctcttg atggctgaac atgcgccaaa
    14581 tgctaagatt acaactattg atcgtaatcc agaaatgatt ggttttgcca aggaaaattt
    14641 tgcccagttt gacagtcgca agcaaatcac tctcctagag ggagatgcgg tggatgtctt
    14701 atctacactg acagagtctt atgatttcgt ctttatggat tctgccaagt ctaaatacat
    14761 cgtctttctg ccagaaatcc tcaaacattt ggaagttggt ggtgtggttg tcttggatga
    14821 tatttttcaa ggcggtgatg ttgccaagga cattatggaa gtccgtcgag gtcagcgaac
    14881 catctatcga ggccttcaaa gactatttga cgcaacctta gacaattcag aactcaccgc
    14941 aacattagtg cctttaggag atggtattct catgcttcgt aaaaatgtag cagatgttca
    15001 attgcctgac agcgaatgat tttcagaaaa atttaagaaa aaatagtaaa atagatagag
    15061 taacacttat ctcaaaggag tagacatgaa gaaaaaatta ttggcaggtg ccatcacact
    15121 attatcagta gcaactttag cagcttgttc gaaagggtca gaaggagcag accttatcag
    15181 catgaaaggg gatgtcatca cagaacatca attttatgag caagtgaaaa acaacccttc
    15241 agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt tttgaaaaac aatatggctc
    15301 agagcttgat gataaagagg ttgatgatac tattgccgaa gaaaaaaaac aatatggcga
    15361 aaactaccaa cgtgtcttgt cacaagcagg tatgactctt gaaacacgta aagctcaaat
    15421 tcgtacaagt aaattagttg agttggcagt taagaaggta gcagaagctg aattgacaga
    15481 tgaagcctat aagaaagcct ttgatgagta cactccagat gtaacggctc aaatcatccg
    15541 tcttaataat gaagataagg ccaaagaagt tctcgaaaaa gccaaggcag aaggtgctga
    15601 ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa acaaaagaaa atggtggaga
    15661 aattaccttt gattctgctt caacagaagt acctgagcaa gtcaaaaaag ccgctttcgc
    15721 tttagatgtg gatggtgttt ctgatgtgat tacagcaact ggcacacaag cctacagtag
    15781 ccaatattac attgtaaaac tcactaagaa aacagaaaaa tcatctaata ttgatgacta
    15841 caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa aatgattcaa catttgttca
    15901 aagcattatc ggaaaagaat tgcaagcagc caatatcaag gttaaggacc aagccttcca
    15961 aaatatcttt acccaatata tcggtggtgg agattcaagc tcaagcagta gtacatcaaa
    16021 cgaatagtcc aaatcaatga gtcagggaaa aaactcgact tcaggaaaaa atgaagcaaa
    16081 cattcccaca ataaaacgca tagtacaagg tttgtactgc cccccaaaaa agttagacaa
    16141 ttaatttatc cgaaggattt agttctgtat
//
LOCUS       DAVMCN010000039        16110 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVMCN010000039 DAVMCN010000000
VERSION     DAVMCN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16110
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.039"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            35..1341
                     /locus_tag="VYP85_001476"
                     /pseudo
     CDS             35..1341
                     /locus_tag="VYP85_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1440..3062)
                     /gene="groL"
                     /locus_tag="VYP85_001477"
     CDS             complement(1440..3062)
                     /gene="groL"
                     /locus_tag="VYP85_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1881971.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3078..3362)
                     /gene="groES"
                     /locus_tag="VYP85_001478"
     CDS             complement(3078..3362)
                     /gene="groES"
                     /locus_tag="VYP85_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1881972.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVVTGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3518..3913)
                     /locus_tag="VYP85_001479"
     CDS             complement(3518..3913)
                     /locus_tag="VYP85_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1881973.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3991..4752)
                     /locus_tag="VYP85_001480"
     CDS             complement(3991..4752)
                     /locus_tag="VYP85_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1881974.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(4794..5420)
                     /locus_tag="VYP85_001481"
     CDS             complement(4794..5420)
                     /locus_tag="VYP85_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1881975.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(5436..5753)
                     /locus_tag="VYP85_001482"
     CDS             complement(5436..5753)
                     /locus_tag="VYP85_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1881976.1"
                     /translation="MIQPASLEELASLVEKAGKKVFIFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(5750..6049)
                     /locus_tag="VYP85_001483"
     CDS             complement(5750..6049)
                     /locus_tag="VYP85_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1881977.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(6386..6577)
                     /locus_tag="VYP85_001484"
     CDS             complement(6386..6577)
                     /locus_tag="VYP85_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1881978.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6738..7412)
                     /locus_tag="VYP85_001485"
     CDS             complement(6738..7412)
                     /locus_tag="VYP85_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881979.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(7418..7864)
                     /locus_tag="VYP85_001486"
     CDS             complement(7418..7864)
                     /locus_tag="VYP85_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1881980.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7978..8481)
                     /locus_tag="VYP85_001487"
     CDS             complement(7978..8481)
                     /locus_tag="VYP85_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1881981.1"
                     /translation="MKNYQEWYRNISSRLTSCPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(8478..8840)
                     /locus_tag="VYP85_001488"
     CDS             complement(8478..8840)
                     /locus_tag="VYP85_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1881982.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8906..9901)
                     /locus_tag="VYP85_001489"
     CDS             complement(8906..9901)
                     /locus_tag="VYP85_001489"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1881983.1"
                     /translation="MDKPMLVFKRFGHQIYLMVQKEAKRCGIEFMGGPQGQVEFKDET
                     FRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYDVSAGEILVDGVN
                     VQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHIDGVDTKAMTRSE
                     VHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHHFIMTLPDGYDII
                     LDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQKAMDRLMEGRTS
                     FVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNSQFTEDEAEE"
     gene            complement(10025..10741)
                     /locus_tag="VYP85_001490"
     CDS             complement(10025..10741)
                     /locus_tag="VYP85_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1881984.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11622..13037)
                     /gene="ply"
                     /locus_tag="VYP85_001491"
     CDS             complement(11622..13037)
                     /gene="ply"
                     /locus_tag="VYP85_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1881985.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13048..13380)
                     /locus_tag="VYP85_001492"
     CDS             complement(13048..13380)
                     /locus_tag="VYP85_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881986.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13451..14059)
                     /locus_tag="VYP85_001493"
     CDS             complement(13451..14059)
                     /locus_tag="VYP85_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881987.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14072..14530)
                     /locus_tag="VYP85_001494"
     CDS             complement(14072..14530)
                     /locus_tag="VYP85_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1881988.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14655..15054
                     /locus_tag="VYP85_001495"
                     /pseudo
     CDS             14655..15054
                     /locus_tag="VYP85_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15819..16079)
                     /locus_tag="VYP85_001496"
     CDS             complement(15819..16079)
                     /locus_tag="VYP85_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1881989.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
BASE COUNT         4757 a         3632 c         2884 g         4837 t
ORIGIN      
        1 aaaagcgaca aaacaactca ttagaaagat tcatatggaa caattacatt ttatcacaaa
       61 actgctcgat attaaagacc ctaatatcca gattttagac atcatcaata aggatacaca
      121 caaggaaatc atcgccaaac tggactacga cgccccatct tgccctgagt gcggaaacca
      181 attgaagaaa tatgactttc aaaaaccttc taaaattcct tatcttgaaa cgactggtat
      241 gccttctaga attctcctta gaaagcgtcg tttcaagtgc tatcactgtt caaaaatgat
      301 ggttgctgag actcccctgg taaagaaaaa tcaccaaatc cctcgtatca tcaaccaaaa
      361 gattgctcaa aagttaattg aaaaaatttc tatgactgat attgcccatc agctggccat
      421 ttcaacttca actgtcattc gcaagctcaa tgactttcac tttgagcatg atttttctcg
      481 gcttccaaag attatgtctt gggatgagta tgccttcact aagggaaaga tgagtttcat
      541 tgcgcaagat tttgataatc ttaatattat cactgttctt gaaggcagaa cacaagctgt
      601 catccgaaat cactttcttc gctacgatag agccgttcgt tgtcaagtga aaatcattac
      661 gatggatatg tttagtcctt actatgactt ggctaaacag cttcgctttc aaatttctag
      721 gctcaggctg aaacagtctc ccagactgtt tcactcccga atgctaaaat cgtgttggat
      781 cgctttcaca ttgtacaaca tcttagccgt gctatgagtc gtgtgcgtgt tcaaattatg
      841 aaccaattgg atcgaaaatc ccatgaatac aaggctatca agcgctactg gaagctcata
      901 caacaggata gccgtaaact gagtgataag cgattttatc gtcctacttt tcgtatgcat
      961 ttaaccaata aagagatttt agacaagctt ttgagctatt cacaagactt gaaacatcac
     1021 tatcagctct atcaactctt gctgtttcac tttcagaata aggaaccgga gaaatttttc
     1081 ggacttattg aggacaatct taagcaagtt catcctattt ttcagactgt ctttaaaacc
     1141 ttcctcaaag ataaagaaaa gattatcaac gcccttcaac tacactattc taacgccaaa
     1201 ccggaagcga ccaataatct catcaaactt atcaagcgca atgcctttgg ttttcgaaac
     1261 tttgaaaact tcaaaaaacg gatttttatc gctttgaaca tcaaaaaaga aaggacgaaa
     1321 tttgtccttt ctcgagctta gctgacttca acccactaca gttgacaaag agcctataaa
     1381 aagaagggtt agtcattccc tccttttgtg ttttttataa gttgttttct atagaaagct
     1441 tacatcatcc cgcccatcat gcttggatcc attgctggag ctggggctac tggttctggt
     1501 ttattggcta cgactgcttc tgttgtcaaa atcaagctgg ctacagatgc tgcattttgt
     1561 agggctgaac gactcacttt aactggatca atgatacctt gatcaatcat gttaacccac
     1621 tcgccagttg ctgcgttaaa tcctatacca agctcagcat ttttcaaacg atcgataacg
     1681 atagatcctt caaatcctgc attgtgagca atttgacgaa cgggttcttc caaagcacgg
     1741 agaacaatat tacgtcctgt tgcttcatct cctgtcaatt ccaaggtagc aacagctgga
     1801 atcacattgg caagagctgt tccaccacct gcaacaatac cttcttcaac agctgcacga
     1861 gtagcgttga gggcatcttc aatgcggagt ttcatttctt tcaactcagt ttcagttgcg
     1921 gctccaacct taataaccgc tacaccacct gacaatttgg ccaagcgttc ttgcaatttt
     1981 tcacggtcaa attcagaagt tgtagtttcg atttgagact tgataaccgc aacacggtga
     2041 gaaatcgctt caggatttcc tgcaccttct acaataaccg tgctatcttt gtccacggtc
     2101 actctcgctg cttgaccaag agcttcaatt gtcgcatctt tcaactcaag accaaggtct
     2161 tctgtgataa ctgttccgcc tgttaagatg gcgatatctt caagcatggc tttgcgacgg
     2221 tcaccaaaac caggtgcctt gactgctact acgttgaagg ttccacgaat cttgttcaaa
     2281 acaagagttg gaagagcctc gccatccaca tcatccgcaa taatcaagag tggacgattg
     2341 ctttggagaa tgctttccaa aagtggcaag atttcttgga tattggaaat tttcttgtct
     2401 gtaatcaaaa tgtacggatt ttcaaggtca gccaccattt tttcgctatc tgtcaccatg
     2461 tactgtgaaa ggtaaccacg gtcaaactgc attccttcta cgacttcaag ctctgtttcc
     2521 ataccacgtg actcttcgat ggtgatgaca ccgtctttgc caactttttc cattgcttca
     2581 gagatgtact caccaacttt ttcagaacga gaagatacgg ctgcaacttg agcgatagct
     2641 tctttattgg caacagggat ggcgttgttt ttcaaagctt caactgctgc ggcaactgct
     2701 gtttcaatcc cacgacgaat accgattgga tttgcacctg ctgtgacgtt tttgattcct
     2761 tcacggacga tagcttgggt caagactgtt gcagtcgtag ttccgtcacc tgcgatatca
     2821 ttggttttag aagctacttc tgatactaac ttagcaccca tattttcaaa atggtcttcc
     2881 aattcgattt ctttggcaat ggtcacaccg tcattggtaa tcaagggtga accgaatgac
     2941 ttttcaagaa cgacattgcg accttttggt cccaaggtta ctttaacagt gtctgcaagg
     3001 atatcgacac cacgaaccat ggctgaacgg gcatctgatg aaaatttaat ttcttttgac
     3061 atacttactt tctccttcta ttcctcaatg attgccaaaa tgttagcttc gcctacgatg
     3121 atgtactttt catcgccatc tttgacatca agacctgcgt gggcttcaac taagacacga
     3181 tctccagttt taacacttgg agcaaccaag tcaccgttca aggtacgaac accttgtcca
     3241 gtaaccacaa cttgagctgt tttggttttt tcttgggctg agcctgcaag gacaaagcct
     3301 ccaacagttt gttctttttc ttctattttt aagaccacac ggtcccctaa tggtttcaac
     3361 atctgatttc ctccataatg agatagatat tattagcact ctttgaactt gagtgctaat
     3421 tcatagttct attgtatcac ttggtcagaa ataatcaaga aaaaagtctg actttctcaa
     3481 gataaaaagc ctgagaccaa ctcagacttt ttaattctta aaatggcaat tcttcctctt
     3541 ccaagaccaa atctgccaaa tcttggcctg cattattttc acgcatagca cgttgggcac
     3601 gactttccaa gagttggaat cctgtgacaa gtacttcggt cacgtagttc atttggccat
     3661 ttttctcaaa gcgacgggta cgcaattctc catcaacgga aatgagacta cctttggttg
     3721 cgtagcttgc caaagtttct gctagtctgc cccataggac catattgaca aaatcagctt
     3781 cacgttcacc gttttggtct ttgtaacgac ggttcacagc gatagttgct cgcgctaccg
     3841 acttgtcatt gttggttttg tgcaattctg gtgtagacgt taaacgtcca atcaagataa
     3901 ctttattata catattttct tcctcctact tatctattcg taggaaatca aaaaaagtta
     3961 cagaaatttg taacttttcg agaaaatttt ttatttttta tgaaccatga aacctgtcgc
     4021 ctgttgattg gccataatgg tcatatctgt aatctgaaca cgacgaggtt gactagtcac
     4081 atagactact gtatctgcaa tatcctgagc ttgcaaagct tctattcctt ggtaaacgga
     4141 cgcagctcgt tctttatcac catgaaaacg cactgtagaa aaatctgttt cgacaattcc
     4201 aggctgaatg gtcgtcacct tgatatccgt tgcgatggta tcaattcgca gtccatctga
     4261 aaaggtctta actgccgcct tggtggctga gtaaacagct gcaccagcat aggcataaat
     4321 tcctgcggtt gaccccatat tgataatatg accttgattg gcttttacca ttgctggcaa
     4381 gaaacagcga gtgactgcca tcaaaccttt gacattggta tccaacatgg tcagcatatc
     4441 caactcttca tagtcttgat agggagctaa gccaagagcc agtcctgcgt tattgaccag
     4501 gatgtcaatc tgacctatcg tttctaaaat atcagagcag acagtcttta ccattgtcat
     4561 atccgtgaca tctaggagaa aagtccaaac tgtttgattt ggaaaagttt ctgcaaactc
     4621 cgccttaaga gcttctagtc tgtctatccg tcgtcctgtt agaacgacat cctcaccctg
     4681 ctccagataa gcacgcgcaa tcgcttcacc gattcctgat gtcgctcctg taatcacaac
     4741 attttttgcc atcttatttc cttctagctg gtctatcaga tattaacaac ttcttaggca
     4801 gtccagtgtt tcgctgggtc gaacggtgtt ccgacaactt ggtcttctga taattcaagc
     4861 accccacgtt tttgtggagc atttggcaga tgcaattcac gaggactgca catcatacca
     4921 aaactctttt caccacgaag ttcacctggg aaaatgagat tcccttttgg catcatagct
     4981 ccaggaagcg cgacaatggt tttcaacccc acacgcgcat tgggagctcc tgcaacgatt
     5041 tgtacagtct tatcacttgc gactgcaact tggcagatgt tgaggtggtc actatctgga
     5101 tgggctacca tctcaacaat ttcacctaca acaaacttag gttccttatc attaacaatt
     5161 tcttctgtaa aaccttccgc ctgcaactct tggttcaaac gagcgacttg ctcatctgtc
     5221 aaaaagactt gaccgcgctc tgcaatttca aataaacttg aaacttcgaa aatattccaa
     5281 gccactgttt ccccattatc tttgagaaaa acacgggcta ccttgccttt gcgctccaca
     5341 tccagtttgg catctccgct atttttcacg atgaccataa ggacatcacc gacatgttct
     5401 ttattatatg taaaaatcat tgtttccttt ttctcctatt tcagtcctgc taaaaagtca
     5461 ttgatttgtt gcttgctttt acggtcgcga ttgacaaaac gaccgatttc cttgtccttt
     5521 tctagaacaa caaggctagg aattccgtaa acatcccaga gtttggccaa atccatatac
     5581 tgatctcggt ccattcgaat aaaggtgaac tctggattgg tctcctcaat ctctggtaag
     5641 gcaggataaa tataacgaca atcgccacac cagtctgcca caaaaatgaa gaccttcttg
     5701 cccgcttttt ccactaaaga tgctaattct tctaaacttg ctggctgtat cataagactt
     5761 cctcctcata gactaggtct tcattttcat agacaaaggt ataatgacgg ccatcctcaa
     5821 aaatgacgcc accaaccaag ctctccagac tgctttcgta aacttgaaca taaagggtcg
     5881 caatttcccc catgtcggaa aaatggtctc gcacaatctc tgtcaactct tcctgagtct
     5941 tcatgagctt acggtcatct gcaacttttt tcgtagcaag agcaaggctt ccgataccta
     6001 gcagagccaa gcctgccatc cacatttttt tagctttcat accattcatt ttaacacaaa
     6061 aaaggcttca ggacaaatga ggaagcagca gaaaagcaag taaaaagcct cttcctttaa
     6121 ggaaaaggac ttcttatact caatgaaaat caaagaccaa actaggaagc tagccgcagg
     6181 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagct caaaacactg
     6241 ttttgaggtt gtggatgaag ctgacgtggt ttgaagagat tttcaaagag tattattctt
     6301 attgccaggc acctaagttg ccaacgtagt aactatcagg tgtgtaggta ttgcgaagca
     6361 tcttacctga tgaagccaga taatactact tgccattgtc tttgacccaa tcattcgcaa
     6421 tcatggaacc agaagaactt acataatacc attctccctt gtcataaacc caagtactga
     6481 ctttcatggt tcctgagcaa ttaaaggcaa aaaaactgtc caatatcatt cgttttttaa
     6541 aagcatttga cactacatca tctacgctgt agtacataga tacatcaaac gtaaaagcca
     6601 aaatatcgaa aaatatacaa cttttaaagg cagcatttca ttttttaaag tctaacaacc
     6661 atagaactga aatcagagca aggcatcaat ttcctactct tagtacgtct attttgatgg
     6721 ttgaagtgaa gattttttta tttaacgtag acaatttcca acttcccaaa agccacatct
     6781 ccacggataa tcaaggtttt gctggttggg gctacaggag cgtcagcctt agctgcacca
     6841 aaggaggttt ctactttcaa atctacacgc cagtgttgtg gaacatagac ggttgcattc
     6901 ccgaaggcca cttcaatatt taaagttgca aaatcaccta gcatctctgc attatcatag
     6961 tagattttag catccccaaa agcgacttcc acttggtcat ctacgagatc ttgatcttgc
     7021 ttatagaagg tcccgctacc aaaagcgact tccttatccg tgacgactgt ttttttccca
     7081 ttgtaccacc attttttttc attccagaac ttacttgaat gcgtcagata accaacacca
     7141 agtaccacca agatgctagc ccaaataaga gaatgattgg taactggtaa caagtcataa
     7201 gcgtaatttg caatgatgag cgccagtaaa cctgtaaaaa ctgccgaagt gagatgacgt
     7261 ctaaggatgg actcaatgga cttataagca aaaaaaacaa tacctagtaa aggccatatt
     7321 ttaccatcca aagaaggaat tccaaaattc ccttgcagca agatccaagc tgctaaaacc
     7381 aataaaacaa taccaaatgc tttctttttc atgtttttta cctcatgttt cttagatttt
     7441 cttttaggag ggattggtaa tgccgtgaga catgaacctc cttgtgcgtc tgataaaagg
     7501 aaatggtgcc cgttcctgaa aaggacttgt ccactgagta aatctgacgg atgtttgcga
     7561 tcgttgactt ggaaactcga ttaaaatagc gaggcaagat agactccaac tcatagagct
     7621 tgaggcgaac ctcataagct tccttctggt tatgagcgta gatcttgctc ccttctgttt
     7681 caaagaagag aatttctgac aggtctagat aatattcacc tgtccccttg taaaaagtca
     7741 acctcggagc ctttgactct tgcaagaggc gttgcaagtc tgcaatttca tctgtcaaag
     7801 tgggggtctt gatgacaatt tcagtctcct ctaaattgcc gtcaatctca attcgtaact
     7861 tcatcacatc tcctttctga ctctactata tcaaagctaa gttaggaata caagggcaaa
     7921 aaagcaagtg gtcaatttga agcagtaagt ggttgtagga ctagcttaac ttacatgtca
     7981 gaataggaag aaaaggaatc cccacaccaa accacaagca tagccaacca agacatcctt
     8041 gggataatga acacccccta aaaccctcac caaccccagc aaagctgaaa agatcaagca
     8101 tactaagcca ataggtagac tagcatgcag acaggccatg gagatgatag ttgccgaaaa
     8161 gacatggcga ctgggcatcg accgtcccga actatcctta tcaagaaggg gacagatatc
     8221 ccaagtttca taaggtctcg ggtgattgat tttcttacga aacagggaca aggccacaaa
     8281 acctgatgca ggaataagca cataaacccc aacttgctga ccaagtccta gttgcaggta
     8341 agtggtgact agcaagatca gatagaccag gggcatggcg actgtcatca aacgattgaa
     8401 actgcgtaat aggaataaaa gaattggaca actagttagt ctggagctga tatttcgata
     8461 ccattcttga taatttttca tttatgcttc tcatactttt ctagaacttg ttgagatgtt
     8521 ttccccttgg caagccaatc cactagcttg tccaagcgac gtatttcctg catcagagga
     8581 tcatcaattt cctcaatacg gacaccgcaa atcttccctg taattgcaat tcgttcaggg
     8641 acataatatg gtgcttgtct aaaaaaatct ccgtaagtaa catccctatc cagacaagca
     8701 agaacatcac tcacttcata ccctgtcaac caactggtca cttggtgaac tgactctgcc
     8761 tttccaccct ttcgctcaac ttttgcaatc aaggctaagt agacagcagc aaatttcata
     8821 ttgtataatt tctgactcat acttctctct ttctatgtgt actagtataa ataagaaaaa
     8881 gaaggccgtc aagccttctt ttgatttatt cttctgcttc atcttctgta aattgactat
     8941 tgtacaagtc agcgtagaag ccaccttgcg ccatcagttc ctcatagttg ccttgctcga
     9001 tgatatttcc atctttcatg accaagatca agtctgcatt tcggatggtt gacaagcggt
     9061 gggcaatgac aaaggatgtg cgtccttcca tcaaacggtc catggctttt tggatcaatt
     9121 cctctgtccg tgtgtcaaca gaagaagtcg cctcatccaa aatcaaaagc ggtgcatcct
     9181 taagaagggc acgagcaata gtcaatagtt gtttttgtcc tacagacaag gtcacggtgt
     9241 catccaagat gatatcatag ccatctggca aggtcataat aaagtggtga attcccacag
     9301 ccttactagc ttccatcatt cgttcatcac taatccctat ttgattatag atgagattgt
     9361 ctcgaatagt tccttcaaag agccaggtat cctgcaagac cattgaaaag gcatcatgca
     9421 cttctgaacg cgtcatagcc ttggtatcca caccatcaat atgaatactt cccttatcaa
     9481 tctcatagaa tttcatcaaa agattgacaa tggttgtctt accagtccca gtcggcccaa
     9541 caatggcaac cttttgacca gcatgagctg tcgcagagaa gtcatagtct tgaacattga
     9601 caccgtccac cagaatttct cctgctgaca cgtcgtagaa acgtggaatc agattgacca
     9661 gagttgattt accagaacct gttgacccaa taaaggccac tgtttgacca gtttctgctt
     9721 taaagctaac atgttcaata actgcctccg aatttgccgc atagcggaag gtctcatcct
     9781 taaactcgac ctgaccttgc ggcccaccca taaattcaat gccgcaacgt ttggcttcct
     9841 tttgcaccat caggtaaatt tgatgaccaa aacgcttaaa gactaacatc ggtttatcca
     9901 taatctcccc cttctaaata aaaatagttc tctggagaat aattaaattt ctatgagaac
     9961 tattttcttg attaaaaaaa tcccaagtga ttttctcact taggatcatg ttctataggt
    10021 taaattaaaa cccatctacg ttcgtataaa tcttttggac gtcttcgtcg tcttcaagaa
    10081 cgctgtaaag tttttcaaag gtttcaaggt cttcgcctga caattccact tctgactgag
    10141 gaatcatttc caattcagtc acttggaatt cttcaatacc agactcacgg agagcaacga
    10201 tagccttgtg aaggtcagtt ggcgctgtgt aaactgtgat tgtaccttct tgtgcttcta
    10261 cgtcatccac atccacatcc gcttcgagca attgctcaaa gactgcgtcc gcatcttcac
    10321 ctccaaatac aataacacct ttgttgtcaa aaaggtaaga aacagaacct gaagcgccca
    10381 tgtttccgcc gtttttacca aaggctgcac ggacattggc tgctgtacgg ttaacgttag
    10441 aagtcaaagt atccacaatt agcatagagc catttggccc aaaaccttcg taacgtcctt
    10501 ctgtaaaggt ttcgtctgtg tttcctttgg ctttatcaat cgctttatcg ataatgtgtt
    10561 ttggcacttg ggcttgttta gcacggtcga taacgaattt caaagctgag tttgattctg
    10621 gatctggatc acctttttta gctgctacat agatttctac accaaatttt gcatatactt
    10681 tagagttagc tccatcttta gccgttttct tggctacgat attggcccat ttacgtccca
    10741 ttaggaatct ccttttttca cattttaatc tttcttatta taacacaagt ttttttgatt
    10801 ttcactagag gaaatggatt ttattagcaa atcaagctag gatagcactt tacctgctaa
    10861 gatggtcttg cctttctatc tttatcaaca ggcactcatc cacattcaaa aaacaaacta
    10921 gaccattatc tgcaaataga aagtttcagc caagtttgac aaagtcagct caaattactg
    10981 tttgaagttt gtagatataa gcgacaaaaa caatcatact gcaccttttg ttgacagtct
    11041 actccagaca tatcatagtt caagtaaata ctttgaaatt caacagttct tataggcgct
    11101 attgtattct aagaaatcaa tagaagagtt tctaagcaaa cctctaatac tcaataaaaa
    11161 tcaaagagca aactagaaag ctagcctcag gttgctcaaa acactgtttt gaggttgcgg
    11221 atggggctga catggtttga agagattttc gaagagtata atttacgtgt tcccaagatg
    11281 gagaagttag actagtacac tggcacttct aaaacattgc tagcaattga tttgttcata
    11341 tttaatttca ttttttccat aaatgggtat tagatataaa cagcaaaata tttccgatac
    11401 gtgtcgttct tgaatttcca atcatctaaa acaagtaaag gataatcaat cccctgtata
    11461 tcaaggaatt ggctaccctt tttacttttt tacacattct gtttgataga ttcattttaa
    11521 catcacgagc atactccaat ggaaatcgct aggcaagaga taaactttca gatatccgca
    11581 gagagatcat cgcctctttt tgtcgcaagc attctcctct cctagtcatt ttctacctta
    11641 tcttctacct gaggatagag agttgttccc caaatagaaa tcgtccgctt acgcactagt
    11701 ggcaaatcgg ttttttcata aaccgtacgc caccattccc aggcaagccc ggtacactct
    11761 ctaattttga cagagagatt acgaacattc ccttttaaag gaatactagt ggtaaagtga
    11821 gccgttaaat cctgcccatt tctgtcccaa gccttaggag tcaagacttc cttaccttga
    11881 tgatcatagg ataattcatt ccaagtaata taatattggg caacataggc accactatga
    11941 tccagcagta aatctccgtt tctgtaagct gtaaccttag tctcaacata gtctgtacta
    12001 ttttgaaagg tcgcaactac attgtcacgt aaaaaagaag ttgtatagga aatcggcaag
    12061 cctggatgat ctgctgtaaa gcgactgcct tcttgaatca agtcctctac catatccacc
    12121 ttgcctgtta caactcgggc acccgaactt gggtcgcccc ctaaaataac cgccttcact
    12181 tctgtattgt ccaaaatctg cttccactct gtctgaggag ctaccttgac tccttttatc
    12241 aaagcttcaa aagcagcctc tacttcatca ctcttactcg tggtttccaa cttgagatag
    12301 acttggcgcc cataagcaac actcgaaata tagaccaaag gacgctctgc agaaattcct
    12361 ctctgtttta aatcctctac cgttacagta tcttgaaaca catctcctgg atttttaaca
    12421 gcgtctacgc tgactgtata ataaatctgc ttaaaattaa caatctgaat ctgcttttcg
    12481 cctgaatgga cagagttaaa atcaatatca agagaattcc ctgtcttttc aaagtcagaa
    12541 ccaaacttga ccttgagttg ttccatgctg tgagccgtga ttttttcata ctgcattcta
    12601 gctgggacat tattgacctg accataatct tgatgccact tagccaacaa atcgtttacc
    12661 gctccgcgaa cacttgaatt gctggggtct tccacttgga gaaagctatc gctacttgcc
    12721 aaaccaggca aatcaatact ataagtcatc ggagcacgat cgaccgcaag aagagtggga
    12781 ttattctcta acaaggtctc atccactacg agaagtgctc caggatagag gcgactgtcg
    12841 ttggtagctg ttacagaaat atcacttgta tttgtcgaca agctccgctt ctttctttcg
    12901 ataacaacaa actcatcggg tagctgatta ccctctttga tgaaacgatt ttcaatactt
    12961 tctccctgat gggtcaagag tttcttttta tcgtaattca tagctagtat aaagtcattt
    13021 actgctttat ttgccatctt ctacctccta ataagttcct ggattgagtt gcataaactc
    13081 agacttgttc agcgaaatca gccgtggttg gactaagtaa tccaaaattt cctcgtacaa
    13141 ttcttctgag acattgcgtc gccgtctggc taaataagaa gtcggaatga ccgtattatc
    13201 caacataaat accttatcta agtcaatcaa ggttggtctt gtaaaaggat tacgagctag
    13261 atccggctct tctatcataa agttcttgac caaacgtctg gtcaagagag ctggtttgaa
    13321 ggtctgattt ttaaccaact ctttgttttt agtcatgctg ttgtcaatac agatatacat
    13381 atgattcttc acagccaaat cgctactaat agtcggaaaa ggcaaataaa gagctacaac
    13441 atctcctctc ttaatcaagc aagagcaccc ccttttctcc taatgtaaca tagacaggat
    13501 tgaccaagtc ttctgattga ctcagaattt ccaaagtttg agtttggcgc gctgtcaatt
    13561 tagtagcatc ttgtctcttc aatacaaaat gcttgtcgcc aataaccttg acaatataat
    13621 ccttctccaa agctgactgg taaatccaca tcagatgttg tctgtcctga gaactcaaga
    13681 gagaaggatt ttcaagcctc ccgatagtct gataaaaatc aaaaacagga gctaactcct
    13741 gccaatctga ttggctagtt gtcaaggcta gaaaaagggc tttgcgagct gatacttctt
    13801 ggttagcctt gagagttact ttcccctcca agttttttag aaatcgggaa actccagaaa
    13861 gcaaattttt ctctaactgc gagaaataaa aacctttcgt tcccagacat aagtctttca
    13921 tgtcgctttc tctagcaaat aagagctcaa acatttgata gtaaaagaaa aatatctggc
    13981 actgggtcgc gctcatcttt tccttatcgg cttctttttt taaccagagc aagggcgaca
    14041 ggtagctgga ttgagacatt tcctctacct cctactcttt tttaactgga gcatctgcac
    14101 tagctgccac ttcttttgac tggatacttt cccactggtt aatctcctct gagataagac
    14161 cttcgcatgt cttgacaaat agggcaaaag ccttggtctt tcctgcatat ttctccgttt
    14221 ggcattgata gaggaatttt tctttctcca ggagttgcgc agttttttgg taagaaatcc
    14281 aattttcctt tgcattatac aaattgataa tcccctcaca cagcaagccg agactggata
    14341 aggcaaccga aatcaaacgg tagcgatcac ctggcatagg aatagcacaa aagacagcta
    14401 tgaggaaacc tgccacgatt tctgttattt ttaatacctt atagcgtcta cgatgttgaa
    14461 cgcttttctt taaaaaatga gctatctgta cgtctaatcg ctctgtcagg tacatttctt
    14521 ctggcgtcat attcgtaact cctttcattt actttgataa tcatagtata acatatttga
    14581 atatcaaagt atagtaaaaa ctggactata acttattaga ctccctgcga aacaaaatat
    14641 ggtatagtag ttctatgaat gatgaagcaa gtaaacaatt aactgataca cgatttaagc
    14701 gtcttgttgg tgttcagcgt accacttttg aagagatgtt agctgtatta aaaacagctt
    14761 atcaaaaaag tcggacaagc tggtaaaatc ttggctgaca gtaattatca agggctcatg
    14821 aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc actaacagtt
    14881 gaagataaag tctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt
    14941 gccaaagtaa aaacgtttaa aatgttttca acaacctgtc gaaatcatcg taaacgcttc
    15001 ggattacgaa tgaatttgag tgctggtatt atcaatcatg aactaggatt ctagttttgc
    15061 aggaagtcta ttatatatat gcacagacat atgaaatctt tttgatacag ccttcttttt
    15121 acatagagag acagcagtta tgatatattt atccattcac aacatcttct gtaccaatac
    15181 tacaataatt ggtacatttt gattacacaa tcgtttcaaa aaatatgatg gaagactgag
    15241 tattttatag taatttcctt cctatcaact agatcaacca gttgagtgtt gaatattgaa
    15301 acaccctagc ctcagcaaag gactatgatc agcatttcct agccaatagg acgctccaaa
    15361 tcacctattc taagtccatc actagcttgg tcagtaagat acagactgca aggcaagact
    15421 gacgtggttg atgagatttt ggaagagtat tacaatcata gattcaccag tagacttgac
    15481 cgcagattta actatagtag attgaaacta gaatagtaca cttctgcttc taaaacattg
    15541 ttagaaatcg atttgactgt cctgatcaat ttgtcctgtt ctcgtttcat tttactatat
    15601 taaaaaacca cctgaaacaa atcaagtgac tagaggataa aaacaaagac tgggcaaaaa
    15661 gttttgaaaa gcaaaaaacg cataatatca ggtcttgaaa aaccttgata ctatacgttt
    15721 gattgtggga agattgactt cattttctcc tgaaattgaa gttttttcta gtttccaggt
    15781 atagacgaat tcaatatagc catctcgcta caattatttt aaccatcgaa aaaatttttc
    15841 agaatttcaa aaatttcatt ttgatctaat gaaatgtcat cattttgaag aatagttgac
    15901 ttcacaagct ctaattctat cacaaagcgg tgcatgtctg cttttaccgc actacttgat
    15961 gttatagccg ataacttttc atctcctagc aaggaagctg tcaaacgggt aatgtcattc
    16021 aaatgctttt taatggactt acttaaacct tgagcacctg tagcagagcg ttccctcata
    16081 tccagccaag ctttagcctt aaaaataatt
//
LOCUS       DAVMCN010000040        14855 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVMCN010000040 DAVMCN010000000
VERSION     DAVMCN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.040"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..291)
                     /locus_tag="VYP85_001497"
     CDS             complement(<1..291)
                     /locus_tag="VYP85_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1881990.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHV"
     gene            534..803
                     /locus_tag="VYP85_001498"
                     /pseudo
     CDS             534..803
                     /locus_tag="VYP85_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            934..1285
                     /locus_tag="VYP85_001499"
                     /pseudo
     CDS             934..1285
                     /locus_tag="VYP85_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1561..2867
                     /locus_tag="VYP85_001500"
                     /pseudo
     CDS             1561..2867
                     /locus_tag="VYP85_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2907..3917)
                     /gene="tsaD"
                     /locus_tag="VYP85_001501"
     CDS             complement(2907..3917)
                     /gene="tsaD"
                     /locus_tag="VYP85_001501"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1881991.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3907..4344)
                     /gene="rimI"
                     /locus_tag="VYP85_001502"
     CDS             complement(3907..4344)
                     /gene="rimI"
                     /locus_tag="VYP85_001502"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1881992.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(4341..5024)
                     /gene="tsaB"
                     /locus_tag="VYP85_001503"
     CDS             complement(4341..5024)
                     /gene="tsaB"
                     /locus_tag="VYP85_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1881993.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            5202..5387
                     /gene="cibA"
                     /locus_tag="VYP85_001504"
     CDS             5202..5387
                     /gene="cibA"
                     /locus_tag="VYP85_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1881994.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLDPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            5390..5542
                     /gene="cibB"
                     /locus_tag="VYP85_001505"
     CDS             5390..5542
                     /gene="cibB"
                     /locus_tag="VYP85_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1881995.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            6360..6593
                     /locus_tag="VYP85_001506"
     CDS             6360..6593
                     /locus_tag="VYP85_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1881996.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6595..8274
                     /locus_tag="VYP85_001507"
     CDS             6595..8274
                     /locus_tag="VYP85_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1881997.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGKEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(8469..10382)
                     /gene="mnmG"
                     /locus_tag="VYP85_001508"
     CDS             complement(8469..10382)
                     /gene="mnmG"
                     /locus_tag="VYP85_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1881998.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMINEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(10392..10847)
                     /locus_tag="VYP85_001509"
     CDS             complement(10392..10847)
                     /locus_tag="VYP85_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1881999.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(10988..12109)
                     /gene="mnmA"
                     /locus_tag="VYP85_001510"
     CDS             complement(10988..12109)
                     /gene="mnmA"
                     /locus_tag="VYP85_001510"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1882000.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(12510..14351)
                     /gene="pspA"
                     /locus_tag="VYP85_001511"
     CDS             complement(12510..14351)
                     /gene="pspA"
                     /locus_tag="VYP85_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV1882001.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSSPTFVRAEEAPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEKKAAAVKKIDEEHQAAN
                     LKSQQALVEFLAAQREGNPKKKKAAQAKLEEAEKAEKEKKKEFDKAQAVVVPEATELA
                     ETKKKADEAKVKEPELTKKLEEAKAKSEEAEKKATEAKQKVDAEHAKEVVPQAKIAEL
                     ENEVQKLEKDLKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAE
                     IAKLEKNVEDFKNSNGEQAEQYRAAAEEDLAAKQAELEKTEADLKKAVNEPETPAPAP
                     KPAPAPAPTPEAPAPAPKPAPAPKPAPAPAPKPAPAPKPAPAPKPAPAPKPAPAPKPE
                     TPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGSMVTGWLQNNGSWYYLNA
                     NGSMATGWLQNNGSWYYLNANGAMATGWLQNNDSWYYLNASGAMATGWAKVNGSWYYL
                     NANGAMATGWLQYNGSWYYLNANGAMATGWVKVNGSWYYLNANGSMATGWVKDGDTWY
                     YLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
BASE COUNT         4128 a         3412 c         2889 g         4426 t
ORIGIN      
        1 aacgtgtaag gcagtttcaa aattatttga acattgagta caatcaacat aggcaatatc
       61 taaattttta taatcatcaa taacctttga atctctagat acgattatca aaataggata
      121 tagagacatc cttctgatct gctttttaca aagtccaatt atatgcggat ctatacctcc
      181 acaatgtcca ttattatacc taactataat atgagccgaa aacactatat ccttaatgtc
      241 tccatatcca tcagggatat taatatttat ttttccacaa ctatattgca ttgtaaccat
      301 ctccttaaac gacgcattat gatatttgat agagaaattt ttatgaataa ctcaataatt
      361 ttatagtaaa tcatgcttat atctcaaaga tacctatttt ctcttgtctc gaccttctcc
      421 aaagaattgc tataatacta ttacaaatac atctgcacta cacttcaaat tttagcactg
      481 tataaaaacg tttcaacaca ctaactttaa gaaaacttcc actattaatt gaaaaagttg
      541 atagagataa attaaagatc tatattgaaa ctcatcccga tgcttatttg actgaaatag
      601 ctgctgaatt caactgtcct ccaacaacta ttcattacgc tctaaaggct atgggatata
      661 gtctaaaaaa gagccgtacc tactgcgaac aagacccaga aaaagtaaat cggttcctta
      721 aagaattgaa tcacttaagc tacctgactc ctatttatat ttatgagaca ggggttgaga
      781 cctattttta tctcgaatat gattgatcct tgagcaggca gttagtctct ctggaagaag
      841 atataattat ttgaattaag atcgagacaa cgcacaccag agattgcgat actgttatag
      901 aagtactaat accctttttt gtttcaatat actatggctc cgatgaccta taaagatacg
      961 atgacgagtg actttttcga agcttgcttc caaaaattct tactacctac tttagataca
     1021 ccatccctta tcattatgga ccatgcaagg tttcacagaa tgaacatgtg taaggagcag
     1081 ggcatagact gttaccactt cctacctatt cacccgagta taatcccatt gagaaaatat
     1141 gggcttacat caaaaacatc tcagaataat attgtcaaat tacgatgctt ttcttgaggc
     1201 acttttgtcc tattcttgtt tcagccgact atactccgtt attgggcagc tacggaacag
     1261 tcgatgggac gatgggggga cataaaaaaa tcctccagtt ttgtttttta taacagtata
     1321 ctggagaatt gacaatctcg gtagatacct cgttatagcg cggttactta ttaggcagtt
     1381 acaaaacaac tgtgaacaga aaacattcca gagtcagaca agactttgga atgctttggc
     1441 tctataattt ctgtagtggg taatcccacc ccaggaatta tagggtcgtt tcttgtagaa
     1501 aaaaagcccc atatgaccta taatgaaaag cgtctaacca actcattaga aagggttcat
     1561 atggaacaac ttaagaatac cacagatttg ctcggattgg aagacaaaaa tatcaaaatc
     1621 ttgtctgttc tgaaatacca aacccatcta gtcgttcagg caaagttgga ttcccccgct
     1681 cctccttgtc ctcattgtca agggaagatg atcaaatacg acttccagaa agcctctaaa
     1741 attccgcttc tcgactgtca gggtttaccc acggtactgc atctcaaaaa gcgccgcttt
     1801 cagtgcaaga attgccttaa ggtggtcgtt tctcaaacat ccattgtcaa gaaaaattgc
     1861 cagatttcca acatggtgag acaaaaaatc gctcagctcc tccttgaaaa gcagtctatg
     1921 actgagattg cccacagatt ggcggtctca acttccaccg tcatccgaaa actgagggaa
     1981 tttaagtttg aaaccgattg gaccaagttg ccaaaagtta tgagttggga tgagtatagc
     2041 ttcaaaaaga gcaaaatgag cttcattgcc caagattttg agtccaaatc catcctcgca
     2101 attttagacg ggcgaactca tgcggtgatt cgaaaccatt tccaacgcta tcagagagag
     2161 gttcgggagc tggtcgaggt catcaccatg gacatgtaca gcccttatta tcggctcgct
     2221 aagcaactct ttccaaaggc gaagattgtt cttgaccgct tccacattgt ccaacatctg
     2281 agccgagcta tgaaccgagt acgaatccaa atcatgaacc aatttgaccg aaaatccttg
     2341 gagtatcggg cgctcaagcg cttttggaac cctcgctttt tcgtttctag gctcgggcta
     2401 aatcagtcca ctggactgat ttactacacc agtatagctt caagctctgt cagaaacgat
     2461 tctatcagcc cacgtttcga atgcacttaa cccatcggga agtacgagat aagctgcttt
     2521 cttactctga gggattacag gttcactacg aactctatca actcctgctc tttcattttc
     2581 aagagaagaa tgccgaccat ttctttggat tgattgagca agaactgcca acggttcatc
     2641 cgctttttca aacggtcttt tggacttttt taagggatag agataagatt atcaacgcac
     2701 ttaagctgcc ttattccaac gctaaacttg aagcgaccaa taatttgatt aagattatca
     2761 agcgcaaagc ctttggtttc cggaacttta acaattttaa aaaacggatt ttgatgactt
     2821 tgaacatcaa aaaagagagt acgaatttcg tactctccag attgtagctt ttcgcctacc
     2881 cactacactt gacaaagagc cactctttat tccatggtat caaaggcaag acttggtttg
     2941 gcattgaggt cccagcctgc gaagttttct ttgttccact cgctgacgct ggcataggca
     3001 atcatacctg cattgtctcc gcagagtcgc agagggggga tgataacctt gacatctgtg
     3061 atttcggctg ctaggcgttc tctgagacct ttattggctg ccacaccacc tgccacaacc
     3121 agggttttaa caggatattt ctccaaagcc ttcttggttt ttgccatgag aatgtccata
     3181 actgctgctt ggaaggaagc acacaaatct tctgtagaca ggctttctcc cttttgctcg
     3241 gcattgtgat aaagattgat aaaggcagat ttcaaacctg agaaggagaa ctccagatta
     3301 tcttccttaa tcatggcacg ggggaaatca taaatatcct gcccctgatg agccagctcg
     3361 tcaatctcac gacctgcagg ataggtcaag cccatgacac ggccgacctt atcataagcc
     3421 tcaccaaccg catcatcacg ggtttcccca acaatcttat aatctcctgc ctccgaaaca
     3481 taaaccaact ctgtgtgtcc gccgctgacc aagagggcta gcaagggaaa ctccaaaggc
     3541 tccacactct gagctgccat gaggtgccca gccatgtgat taacaggaat cagtggaagt
     3601 ccgtgagccc aagcaaaggc cttggcagct gacaaaccaa ctagcaaggc tccgaccaag
     3661 cctggtccgt aggtaaccgc aacagctgtc acgtcctctt cggtaatccc tgcttctgcc
     3721 aatgcctcct cgatacaggc tgtaatgacc tcgacatggt gacgactggc tacttcgggc
     3781 actacgccac caaaacgttt gtgactctca atttgactag caatgacatt ggacaagagc
     3841 tcatcgtcgt ttttcaagac ggcgacactg gtctcatcac aggatgtctc aaatgctaaa
     3901 atatatctat ccttcatcta tttctctctt catgataatg gcgtcctcga ctgggtcatg
     3961 gtagtaggcc tttcgctcag cgatgaccgc cattttttct ttcttgtaaa atgcttgcgc
     4021 tcgttgattt gactttctga cttcgaggaa aatctcctta tctgtcggca attgagcaaa
     4081 caaggctgac gcaattccct gaccctgata ggctcctttg acagcgattt gcaggacttc
     4141 tgcttcaaaa agattctcct gcacagctag aaatccaatc acttctgccc catcataagc
     4201 caatgcatac caagtctggt cttgggacag atctgcttgg atttgctcca gagtccaagg
     4261 actgactagg taaacagctg ccataacagc gtagatggct tgagctaggt caggctgttg
     4321 ttgaattcgc ttgatttcta tcataggcgt ttaatgtagg actcaccaga ctcggtatgg
     4381 ttcttgagcc agttttcctc tgcctcaaca cgtttgaggt aatttggcac aaaatcatgc
     4441 aaggagtctg cttccttgtc ccaggccaaa agagctagat tagctgcatt gggcaatgtt
     4501 tctttgtaat cagtccttgg caagtgtttt tgaatctgct caacaaaggg gccaacttct
     4561 ccgacaaagg ttacctgact agcgcccttg attagctcaa tgactcgctc aaaaggcaga
     4621 tgtgcttctg ccatgacagg tttggcattt tcataaaatc ctgcataaac attattgcga
     4681 cgcgcatcca tcaaggggac aaacaaacct tcttgttggt agggcaccag agccaagaga
     4741 ctcgacatac caaccaactc gatattcaga gtataagcca gagttttggc agtggctacc
     4801 gcgattcgca agcctgtgta gctacctggc ccttccgcca ccacgattcg gtccaaatcc
     4861 ttgggcgtcc agtccaaact ctccatcaaa aaatcaatgg ctggcatgag ggtaatactg
     4921 tgatttttct tgatattaat cgtcgtctca gcaagaacct gcttgtcctc taaaatagcc
     4981 agagaaagag ccttgctgga cgtatcaaaa gctaatactt tcataacaca ttcctatctt
     5041 tttgtctgct tactattata ctacaaaagc tggcacatgg gaattttctt tgcccccaga
     5101 caagagtgcc ctcacttaac taaaaataat taaaaaaaat gctcactttt ccttttcttt
     5161 tccgaatata aaagtgaaca agaaaaaagg aggaaagttc aatgacaaat tttgacattc
     5221 ttgacaatca atttttatcc ttatctgaaa atgaattatc agatattgat ggcggtctcg
     5281 atcccttggt tatctttgga gtagcagtat cttggaaggc tattgcaggt ggaacagcac
     5341 ttataggttc tggtttggca gctggttatt ttttaggagg agattaacta tgatgaaaga
     5401 tttgaacaac tatcgtgaaa tttctaataa ggaattgcaa gaaatcaagg gtggctttgg
     5461 tgtaggtgtt ggtatcgctt tatttatggc aggttatacc attggaaaag accttcgtaa
     5521 aaagtttggt aagtcatgct agataagaaa cacattttta gaaggataaa ttttattgtc
     5581 ttcatctctt acagtttgct cagcattctc aatgatttga acattactac tatcccttta
     5641 ccattcgatt tatctgtttg tattgtttta tttttatgct tcaactctat ttttgagcag
     5701 aacaatgact cccataaaaa taataagctt tgaaaattcc attgtcatgt catgttagaa
     5761 aaatgcaaag accacctcat cttgatagat ggggtggaat tttcgtgtcg taaatctact
     5821 atctctacat ccccaaacaa aaaaacccag cataagcagg gcatctaagc atttaatcca
     5881 aagtaaaata caaaccaaac gacataggtc acgaggagga gaaaaagcga gtagagagtc
     5941 acaaaggtaa ttttccacaa gaacttggtt tgtcatcgtt ccagtttggc aaatagaaga
     6001 tttcctccat aaacgcaagc aacaaaaacg ataaaagcta acaaacgaac tccgatagca
     6061 aaagcaaata agttatacat agggcaacct ccttgactta aaatctatat ggaattatga
     6121 caagcaataa atttcacttc cgttatcaac ataatatatt ttccttgttt ttgcaaacgc
     6181 ttacaaaaga aatcgtcccc taactttctc gtttccgtct tttactaatt tttcattttg
     6241 tggtataatt gaaataattg taacgaatca aggtcaatct agacacaaaa tggaatgaaa
     6301 tcaagcaaat atctgctaaa agtttggaat aagctgacct gtaaatagaa aggaactata
     6361 tgatttacaa agttttttat caagaaacaa aagaacgtag cccacgccgt gaaacaacac
     6421 gcgcgcttta cctagacatc gatgccagct cagaacttga gggccgtatc actgctcgcc
     6481 aacttgtcga agaaaatcgc ccagagtaca atatcgaata tatcgaactc ttgtctgaca
     6541 aattgctcga ttacgaaaaa gaaactggcg ccttcgaaat tacggagttc taatatggcc
     6601 tacactctta aacctgaaga agtcggcgtt tttgccatcg gtggtctagg agaaatcggg
     6661 aaaaacactt acggaattga ataccaagac gagattatca tcgtcgatgc tgggattaaa
     6721 ttcccagaag atgacttgct tggtatcgac tatgtcattc ctgactactc ttacatcgta
     6781 gacaatatcg accgcgtcaa ggctgtttta atcacacacg gacacgagga ccacattggt
     6841 gggattccgt tcctactcaa gcaagcaaat gtccctattt atgctggacc gcttgccttg
     6901 gctttgatcc gtgggaaact cgaagaacac ggcctcttgc gcaacgccaa actttacgaa
     6961 atcaaccaca acaccgagtt gacctttaaa aatctcaagg caactttctt tagaacgact
     7021 cactctattc cagagccttt ggggattgtc attcatactc ctcaagggaa aatcgtctgt
     7081 acgggtgact ttaagttcga ctttactcca gttggagaac ctgcggactt gcatcgtatg
     7141 gctgcgcttg gtaaagaagg cgtgctctgt ctcctgtctg actcgacaaa tgcggaagta
     7201 ccaaccttta ccaactctga aaaagtcgtt ggtcagtcca ttatgaagat tatccaaggt
     7261 attgaaggac gtatcatctt tgcatccttt gcctcaaata tcttccgtct ccagcaggca
     7321 acagaagctg ctgttaagac tggacgcaag attgcggtct ttggtcgttc tatggaaaag
     7381 gccattgtca acggaatcga tcttggctac atcaaagctc ctaagggaac ctttatcgag
     7441 ccaaatgaaa tcaaagatta tcctgcagga gaagttctta tcctctgtac aggtagtcag
     7501 ggtgagccta tggcagccct ctctcgtatc gccaacggaa cccaccgtca agtacaatta
     7561 caaccaggtg ataccgttat cttctcttct agtcccatcc ctggaaacac tactagcgtc
     7621 aacaagctga ttaacatcat ttctgaagct ggtgtcgaag ttatccacgg taaagtgaac
     7681 aatatccata catctggaca cggtggccag caagagcaaa aactcatgct ctgcttgatt
     7741 aagccaaaat acttcatgcc tgtccacggt gaataccgca tgcaaaaagt ccacgctgga
     7801 ctagcagtgg atactggtgt tgagaaggac aatatcttta tcatgagcaa tggcgatgtg
     7861 cttgccctta ctgctgactc agctcgtatc gcaggtcatt tcaacgccca agatatctat
     7921 gtcgatggaa atcgtatcgg tgaaattggc gcagctgtcc tcaaagatcg tcgcgatcta
     7981 tctgaagacg gtgtcgttct ggcagtcgca actgttgact tcaaatcgca gatgattcta
     8041 tctggtccag acatcctcag ccgaggcttt gtctacatga gagagtctgg cgacttgatt
     8101 cgccaaagcc agcgtatcct cttcaatgcc attcgtatcg cactgaaaaa taaggatgct
     8161 agcgtgcaat ctgtcaatgg tgccattgtc aacgctattc gccccttcct ctatgaaaat
     8221 accgaacgtg aaccgatcat catcccgatg atcctcacac cagatgaaga ataaagcaag
     8281 aaaacagccc cgtcctcgga gctgtttttc tctatgcttt cttttgagat taaaactcaa
     8341 tgaaaatcag accagaaggc taggaaaatg cataacttga gttagctccc atagttcggg
     8401 gaactatggg agattggaga tgaatcaaag ccaagctttg aactcattcg taagaagcct
     8461 acgacatatc attttgattt ttgaagagtt ttagaaatac tacgattttt accttccaga
     8521 tacaccatca aaatagaaat atctgctggg tttactcccg aaatacggct ggcttggccg
     8581 atggtttctg gattgatgag tttgaacttc tgacgggctt cggttgcgat agaatcaatg
     8641 tcatcccagt cgatattggc tggaatacgt ttttcttcca tgcgcttcat cttagcaacc
     8701 tgatccatgg cttttgagat gtaaccttcg tacttgattt ctgtttcaat caattcgata
     8761 atcttgtcat ctaattcctc tgcagctggt ccgatgaagg ccaccacatc ttggtaagaa
     8821 acttctggac ggcgaaggaa ttccttggct gtcaccgcat ctgtcaacgg cttgaagccc
     8881 atttcctcaa ccttagcatt ggtttccttg actggcttga gtttgatact gtctaggcgc
     8941 ttcatctcat tatcaaattg atttttcttg atttcaaaac gagcccagcg ttcatcgtcc
     9001 acaaggccaa tctcgcgtcc catctcagtc aagcgcatat cagcattgtc atggcgaaga
     9061 atgagacgat attcagcacg actggtcaag agacggtaag gttcaatggt tcccttggtc
     9121 accaagtcgt cgatcatcac cccgatataa ccgtcacttc gttttagaat caattcaggc
     9181 ttgccttgga ttttcaaagc cgcattgata cccgcgataa tcccttggcc agcagcttct
     9241 tcataacctg atgttccatt tgtctgacca gcagtgaaga gacctgagat tttcttggtt
     9301 tccaaagtcg cacgcaactg atgaggcaag accatgtcgt actcaatggc ataacctgtt
     9361 cgcatcatct ctgcattttc caaaccttta atggaatgaa ccaagtcacg ctggacatcc
     9421 tcaggtagac tggttgagag gccttgcaca tagacttcct ctgtattacg tccttctggc
     9481 tcaaggaaga gttggtggcg ttccttgtcc gcaaagcgca caatcttgtc ttcaatcgac
     9541 ggacagtaac gaggccccac tcccttgacc acacctgtaa acataggcgc acggtggagg
     9601 ttgttttgga taatctcatg actggtacca ttggtgtagg tcaaccagca tggcacttgg
     9661 tccttgacat aatcctcatc acgtgaagtg tatgagaagt gattaggcgc ttcatctcct
     9721 ggttggattt ctgtcacatc gtaattgata gaagaagcct tgacacgtgg aggggttcct
     9781 gtcttgaaac gaccgatttc gaggcccagt tccttgagat tgtcagctag gttaatagaa
     9841 gccaagctgt ggttaggacc tgatgagtac ttgaggtctc cgatgataat ttccccacgg
     9901 agagcagtcc ctgtcgtcac aataacagcc ttagcagcat attcttgatg ggtggctgta
     9961 cgcacaccga caaccttgcc atcttccacc aaaatctcat taatcatggt ttgacgaagg
    10021 gtcagatttt cttgattttc aactgtcttg cgcatctcct tagagtaaag ttccttgtca
    10081 gcctgcgcac gaagagcacg gacagctggc cccttccctg tgttgagcat cttcatctgg
    10141 atgtaagtct tgtcaatggt cttggccatc tcgccaccga gggcatcgac ttcacgtacg
    10201 acaatcccct tagcagaacc accgatagag ggattacaag gcatgaaagc cagcatttca
    10261 atgttaatag tcgcaagcag gaccttacag cccatacggc tagcagctaa ggaagcctca
    10321 accccagcgt gtcccgcacc aattacaata atatcgtatt cttcagtaaa atgataagtc
    10381 atgtttctct cctattcttc aagatgaatg tgtcttagtt ggccttccca atctggtagg
    10441 gccgttttta aaaaggctgg aactagctgg atatcctcaa gcttatccaa gtcaatccac
    10501 tcacagggct gccttttctc atcttcctgc atggtcaacg gggcatcttc aagcaaatcc
    10561 accagataat gaaactcgat attgtgatag gaaacgccgt cttgttcaaa acgattttca
    10621 accacaaaag ctagctgccc agcttgagct ttgacaccca gttcttcctt cacttcacgg
    10681 actaccgcgt cttccgtgct ttcattgact tgaatcgcac ctccaatagt gtaatacttg
    10741 cccttgtctt tggtaactag aagcttgtga ttttggacaa tcaaggctgt agcccgaaca
    10801 ccaaaaaccg tattgtctac ttttgtccga aagtcttgtt gagtcattct tgtcctttcc
    10861 cttaaacgac acaaaaacag tcaaaactac aaagaagtgc aggacaaaaa agcctgcaac
    10921 atccatgagc tttgaccatc atttctattg ctgttattat tgtagcaaat tgagaaaatt
    10981 tgtcaatcta aatgtactga caaacttgtc catcgcggta agcattgtca atcaaaccgc
    11041 cacctagaca ctcttcgcca tcgtaaaaga caactgcctg tcctggtgta atcgcgcgtt
    11101 gtggttctgc aaagataact tctgccttgt ctcctttgac atggacggtc accttagagt
    11161 caggctgacg gtaacggaat ttagccgtac attctagcgt aaactcttct ggcatttcac
    11221 gagtaaagtg gacttgactg gcttctaggc tagttgacat gagcgagtca tggtagaatc
    11281 cttgtcctac atagagaata ttcttgctta gatcttttcc gacaacgaac caaggggcat
    11341 tgtcaccacc gtgttgccca ccgataccga gtccgccacg ctgaccgatt gtatagtaca
    11401 taagacctgc atgctcgccc atatcgcgac catccacagt catcatacga ccaggctgag
    11461 ctggcaggta gttgctgaga aagtttttaa agttcttttc tccgataaag caaatccctg
    11521 tcgagtcttt cttcttagca gtcgaaagac ctgcttcttc tgctagtttt cgaacttcag
    11581 gcttttccaa atgtcctagt gggaacatcg ttttttgaag ttgttcttgc gaaagttggc
    11641 tgaggaaata ggtctgatcc ttgccattgt ccacgccacg aagcatgtga acggtaccat
    11701 cctcatcacg caccactcga gcataatgcc cagtcgctac atagtctgcc cccaaggtca
    11761 tagcatagtc caaaaaggcc ttgaacttga tttccttgtt gcacataacg tccggatttg
    11821 gcgtgcgtcc cgcacggtat tccgctagga aatactcaaa aacgcggtcc cagtactctt
    11881 tttcaaaatt gacagagtag tagggaatgc caatctggtc tgccaccgca accacatcct
    11941 tgtaatcttc ggtcgccgta cagacgccgt tttcatctgt gtcatcccag ttcttcatga
    12001 agataccgat cacatcgtag ccctgctcct tgagcaaaag agccgtcacc gacgaatcaa
    12061 caccaccact catccccacg acaacacgtg ttttagagtt atcactcatg gtaagtctcc
    12121 catctattcg tttattcacg attgaaggtc gtgtgtgctt cacgattgaa ggtcgcttga
    12181 gcagtattca ttataacacg cttggttaga gaagacaagg aagagcttaa aaattgtttt
    12241 ttaaaactta tagtcaatat acagatcatg tgaatgacgt gagtatacct tcttcttatc
    12301 ttcattcaaa taactataat aaataaaaca acccattttc tctaatctat ttttcaagtt
    12361 agagaaaagg agtcgttttt ttaatgacat ttcctgaaat cataagatag gtacctaaag
    12421 aatacgaaca taaatttatt caatcgaacc ttatctttgt ttcaaaatta aaatgtcaaa
    12481 tgttcttaac atgatttaat ttaatcggct taaacccatt caccattggc attgacttta
    12541 tagccatcta cagttgtgtt gactgcaagg gcacctaaac cattgacata gtaccattta
    12601 tctgatactt tgaaccattg gcttgctttc atagcacctg atgcttcaag atagtaccag
    12661 gtatctccat cttttaccca acctgttgcc attgaaccgt tagcgttgag gtagtaccat
    12721 gaaccgttga ctttaaccca acctgttgcc atagcaccgt tagcgttgag gtagtaccat
    12781 gaaccgttgt attggagcca acctgtagcc atagcaccat tagcgttgag gtagtaccat
    12841 gaaccgttga ctttagccca acctgttgcc atagcgccgc tagcgtttag gtaataccat
    12901 gaatcgttgt tttggagcca tcctgtcgcc atagcaccat tagcgttgag gtaataccat
    12961 gaaccgttgt tttggagcca tcctgtcgcc attgaaccat tagcgttgag gtagtaccat
    13021 gaaccattgt tttggagcca tcctgtcacc attgaaccat tagcgttgag gtagtaccat
    13081 gaaccattgt tttggagcca tcctgttgcc attgaaccat ccgtattgta gaagtaccac
    13141 ataccatttt cttgtttcca gcctgttttt ggagtttctg gtttaggagc tggagctggt
    13201 ttaggagccg gagctggttt aggagccgga gctggtttag gagccggagc tggtttagga
    13261 gctggagctg gggctggttt aggagccgga gctggtttag gagctggagc tggggcttct
    13321 ggagttggag ctggagctgg ggctggttta ggagccggag ctggagtttc tggctcatta
    13381 actgctttct taaggtcagc ttcagttttt tctaattcag cttgtttagc agctaagtct
    13441 tcttcagctg cagcacggta ttgttcagct tgctcaccgt ttgagttttt gaaatcttct
    13501 acattttttt caagttttgc aatttcagcg tctaactcat caatcttatc actcaactct
    13561 tcaagttttg atagtttagc ttgtttggca tccaattcag attgaagagg agcacggaga
    13621 ccttctttaa cataatcttc tgagtcagat tcatcaatct ctttgagatc tttttctagt
    13681 ttctgaactt cattttccaa ctcagcgatt ttagcttgag gaacgacttc tttagcatgt
    13741 tctgcatcca ctttttgttt ggcttcagta gcttttttct cagcttcttc tgattttgct
    13801 ttagcttctt ctagtttttt agtaagttct ggttctttta ctttagcttc gtctgctttt
    13861 ttcttagtct cagctaactc agttgcttca ggaactacca ctgcctgtgc tttatcaaat
    13921 tcctttttct tctccttttc tgctttttct gcttcttcta acttggcttg cgcagctttt
    13981 ttctttttag gattaccttc tctttgagca gctaagaatt caactaatgc ttgctgagat
    14041 ttaagattag ccgcctgatg ttcttcatca attttcttta ccgcagcagc tttcttttca
    14101 gttttcttct gatcctcgtc atattttttc tgagcagctt ttgcgtcatc taaagccttt
    14161 tgagcatctt ctactgcttt tttcgcattc ttagcatctt tcttcgctgc atcatagtct
    14221 ttctcagctt tagactgact agctacggga gcttcttctg ctcttacaaa agtaggcgaa
    14281 gacgtaacaa aaccagcccc taagatagcg acgctggcta gacttgttaa aatcattttt
    14341 ttcttattca tctaaattta cctcttttct gatagtcatt tttagactat acttatatta
    14401 agtatactcc ctccgtaaat atttgtcaaa tgttttatat tacattttta ttacaatttc
    14461 tatatcataa gcttctactc caaaaagata aagacactac ttttgccctt ttcgattctc
    14521 tttttaaaca tagcatcatc ttccttcatt cctataaaaa catttccgat gagagagctt
    14581 attttttaat ttcgttaaac aacaaaaaac gcaagcttaa gcctgcggac aatctttata
    14641 gccatttcat ttctttcaca tctgttttac gaactttagc atatttctta gcgcttgtaa
    14701 aatgtagagt aactggttta aatactccgc ttttatctct tcgtaaacct aaaactgcgg
    14761 atcttttatt tttatcctca aaaaatatga cgtccaattt catagtattt ttagataaat
    14821 ccttagctac gatgcaacaa cttgttattt tagaa
//
LOCUS       DAVMCN010000041        13857 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVMCN010000041 DAVMCN010000000
VERSION     DAVMCN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.041"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..242
                     /locus_tag="VYP85_001512"
     CDS             <1..242
                     /locus_tag="VYP85_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1882002.1"
                     /translation="RKSSKLKPLTAEDKACNHALSKERSKVENIFAKVKTFKMISTTY
                     RNHRKRFGLRMNLIAGIINHELGFWFRRKSIEVLS"
     gene            401..2692
                     /gene="pcrA"
                     /locus_tag="VYP85_001513"
     CDS             401..2692
                     /gene="pcrA"
                     /locus_tag="VYP85_001513"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1882003.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSVLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2735..3415
                     /gene="radC"
                     /locus_tag="VYP85_001514"
     CDS             2735..3415
                     /gene="radC"
                     /locus_tag="VYP85_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1882004.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3412..4101)
                     /locus_tag="VYP85_001515"
     CDS             complement(3412..4101)
                     /locus_tag="VYP85_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1882005.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGKPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4119..4760)
                     /locus_tag="VYP85_001516"
     CDS             complement(4119..4760)
                     /locus_tag="VYP85_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1882006.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4843..5058)
                     /locus_tag="VYP85_001517"
     CDS             complement(4843..5058)
                     /locus_tag="VYP85_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1882007.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5066..5413)
                     /locus_tag="VYP85_001518"
     CDS             complement(5066..5413)
                     /locus_tag="VYP85_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1882008.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5418..6533)
                     /locus_tag="VYP85_001519"
     CDS             complement(5418..6533)
                     /locus_tag="VYP85_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1882009.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMH
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6543..7502)
                     /locus_tag="VYP85_001520"
     CDS             complement(6543..7502)
                     /locus_tag="VYP85_001520"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1882010.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7615..8184)
                     /locus_tag="VYP85_001521"
     CDS             complement(7615..8184)
                     /locus_tag="VYP85_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1882011.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTLDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8312..8983
                     /locus_tag="VYP85_001522"
     CDS             8312..8983
                     /locus_tag="VYP85_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1882012.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRSITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8967..9785
                     /locus_tag="VYP85_001523"
     CDS             8967..9785
                     /locus_tag="VYP85_001523"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1882013.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9782..10678
                     /locus_tag="VYP85_001524"
     CDS             9782..10678
                     /locus_tag="VYP85_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1882014.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSYIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10722..11696
                     /gene="pta"
                     /locus_tag="VYP85_001525"
     CDS             10722..11696
                     /gene="pta"
                     /locus_tag="VYP85_001525"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1882015.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(12012..13025)
                     /locus_tag="VYP85_001526"
                     /pseudo
     CDS             complement(12012..13025)
                     /locus_tag="VYP85_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13245..13544)
                     /locus_tag="VYP85_001527"
     CDS             complement(13245..13544)
                     /locus_tag="VYP85_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1882016.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         4033 a         2591 c         2951 g         4282 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aagccgctaa cagctgaaga taaagcctgt aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatga
      121 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg
      181 gtattatcaa tcatgaacta ggattttggt ttcgcaggaa gtctattgag gtattgagct
      241 agtttatgaa aaaattgggt gaaaaagtcg agtgttttag aaacccacag tgtagtattc
      301 tagtttcaat ccactatatt ttgctactcc ccgtaaagtt tctattttcc ctgatttctg
      361 atataataga aatattgact tcaagagtaa ggaagagaag atgaacgcat tattaaatgg
      421 aatgaatgac cgtcaggctg aggcggtgca aacgacagaa ggtcccttgc taatcatggc
      481 aggggctggt tctggaaaga ctcgtgtttt gacccaccgt atcgcttatt tgattgatga
      541 aaagctggtc aatccttgga atatcttggc cattaccttt accaacaagg ctgcgcgtga
      601 gatgaaagag cgtgcttata gcctcaatcc agctactcag gactgtctga ttgcgacctt
      661 ccactccatg tgtgtgcgta ttttgcgtcg agatgcggac catattggct acaatcgtaa
      721 ttttacaatt gtggatcctg gtgaacagcg aacgctcatg aaacgtattc taaaacagtt
      781 gaacttggat cctaaaaaat ggaatgaacg aactattttg gggaccattt ccaatgctaa
      841 gaatgatttg attgatgatg ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat
      901 tgtggcccag tgttatacag cctatcaaaa agaacttcgt cagtctgaat ccgttgactt
      961 tgatgatttg attatgctga ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta
     1021 ctaccagcaa aaattccaat acatccacgt tgatgagtac caagatacca accacgctca
     1081 gtaccaatta gtcaaactct tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc
     1141 ggaccagtct atctacggtt ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa
     1201 ggattacccc aaagccaagg ttgttttgtt ggaggaaaat taccgctcaa ccaaaaccat
     1261 tctccaagcg gccaacgagg ttattaaaaa taataaaaat cgccgtccta aaaatctctg
     1321 gactcaaaac gctgatgggg agcaaatcgt ttactatcgt gccgatgatg agctggatga
     1381 ggctgtattt gtagccagaa ccatcgatga acttagtcgc agtcaaaact tccttcataa
     1441 ggattttgca gttctctatc ggactaatgc ccagtcccgt acaattgagg aagccctgct
     1501 caagtctaac attccttata ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat
     1561 tcgcgatatt attgcttatc tcaaccttat tgctaatttg agtgacaata ttagttttga
     1621 gcgtattatc aacgagccta aacgtggaat tggtctaggt acagttgaga aaatccgtga
     1681 ttttgcaaat ttgcaaaata tgtctatgct ggatgcttct gctaatatta tgttgtctgg
     1741 tatcaagggt aaggcagccc aatctatctg ggattttgcc aatatgatgc ttgatttgcg
     1801 ggagcagcta gaccacttaa gcattacaga gttggttgag tccgtcctag aaaaaacagg
     1861 ttatgtcgat attcttaacg cccaagcgac tctagaaagc aaggcacggg ttgaaaatat
     1921 cgaagagttt ctttctgtta cgaagaactt tgatgacacc actgatgtga cagaagagga
     1981 aactggtctg gacaaactga gtcgtttctt aaatgacttg gctttgattg ccgacacaga
     2041 ttcaggtagt caggagacat cagaagtgac cttgatgacc ctgcatgctg ccaaaggtct
     2101 cgaatttcca gttgtctttt tgattgggat ggaagaaaat gtctttccac ttagtcgtgc
     2161 gactgaagat ccagatgaat tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg
     2221 tgcagagaaa attctctatc tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa
     2281 ttataaccgt ccgactcgtt ttattaacga aatcagttca gacttgcttg agtatcaagg
     2341 tctggctcgt cctgcaaata caagctttaa ggcatcatat agcagtggta gtatttcctt
     2401 tggtcaaggt atgagtttgg ctcaggctct tcaagaccgt aaacgcggtg ctgccccaaa
     2461 atcaatccag tcaagcgttc ttccatttgg tcaatttaca gctggcgcaa aatcagcatc
     2521 tagcgaggca aattggtcca ttggtgacat tgctctccac aagaaatggg gagagggaac
     2581 tgttctggaa gtttcaggta gcggtgctag gcaggaattg aaaatcaatt tcccagaagt
     2641 aggtttgaaa aaacttttag ccagtgtggc tccaattgag aaaaaaatct aattttccat
     2701 ccttctcacg aataataaag tgaggaggat ttttatgtac agtatttcat tccaagaaga
     2761 ttcactatta ccaagagaaa ggctggccaa ggaaggagtt gaagcgctta gtaaccaaga
     2821 gttgctagct attttactca ggacaggaac acgtcaagct agcgtttttg aaattgccca
     2881 aaaagtcttg aacaatcttt caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt
     2941 gcagagtttg tctggtattg ggcgtgttaa ggccatagaa ttacaagcta tgattgaact
     3001 ggggcatcgt attcacaaac acgagactct tgaaatggaa agtattctca gcagtcaaaa
     3061 gttggccaag aagatgcagc aggaattagg ggataaaaaa caagagcacc tggtggcact
     3121 ctatctcaat actcaaaatc aaatcatcca tcagcagacc atttttatcg gttctgtaac
     3181 tcgtagtatc gctgaaccgc gagagattct gcactatgca atcaagcata tggcgacttc
     3241 tcttatcttg gtccacaatc atccttcagg agcggtagcg cctagccaaa atgatgatca
     3301 tgtcactaaa cttgttaaag aagcctgcga actgatgggg attgttctct tggaccattt
     3361 gattgtctct cattctaatt actttagtta tcgtgaaaag acagatttaa tctaaagttc
     3421 attaacgaca tagtcaaaga gtttcttatc tttgggacga ttttcaaaaa gaagttctgg
     3481 atgccattgg acaccgagaa aggcgacatc atccgtactc atgacagcct caatgatacc
     3541 atctttagga tcatgagcca caacttttaa atttggtgct aagtccttga tgctctggtg
     3601 gtggaaggag ttgatatgag agatttctcc atagatttct tggagaacgg tatctggttc
     3661 tgttaccaag cgttgagttg tgtactcaac agaagaatcc tgccaatggt cttcgatatc
     3721 ttggtacaaa gttccaccca tggcaacgtt aaagagttgg gtaccacggc agacagagaa
     3781 aatgggcttt ttctgtttaa tagcttcctt gatgagggcc agttcgaaga tatctctttg
     3841 aaggtgataa tcatcgctat caatggtttt gggtttgcca tagaattttg gatcgacatt
     3901 ttgcccacct gtcaagatga gcttgtcaat caaactgata tagtggcagg ccatttcttg
     3961 atcaccaatc ggtaggatga taggaatccc tccagcatct ttaacgcctt caacaaagcc
     4021 ttttgctgcg tagctcatca tgatgtcatc atctggatga gttttttcgt ttcctgtaat
     4081 cccaataact ggttttttca taaaatgatt ttcgctttct aatcctcttt tcgcatgaag
     4141 tagaggaggg tttggagttc acttgtcaaa tcgacatact gaacgaccac gtcttttggt
     4201 aaatgcagat ggactggtga aaaactgaga attcctttca caccagcatc aaccaagaga
     4261 ttagcaacct cttgtgactt gacgctggga acagttagga tagcagtctt cacatcagca
     4321 tccttgattt tatccttgat ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg
     4381 gtaccgactt caggatggtc gtctaggtca aaggccatga taatcttcat cttgttacgt
     4441 tcgtggaagc ggtagtggag aagggcatgg cccatatttc caataccaac cagcatgaca
     4501 ttggtaatag agttgtcatt gagcaaatcg gcaaaaaatg tcattaattt tttgacatca
     4561 tagccaaaac cacgacgacc aagttcacca aaataggaaa aatcacgacg tacggtagct
     4621 gaatcaatac cgatagcctc tgcaatttgc ttagagttgg cacgttcaat cttttctgca
     4681 tgaaatctct taaaaattcg atagtagaga gagagtcttt ttgctgtagc ttttggaata
     4741 gcaaactgtt tatctttcac aaaatcacaa cctttctatt cttctatttt atagaaacat
     4801 tgtgaaaaaa tcaacaaaaa taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa
     4861 atctgcatga gatagaaaac ggtagaggtc tccgaccagc ccctgataaa cttttttgcc
     4921 cctaaaagtc agagaagtca cataaagtgt atctggtaag gttacacatc ctgacaaagt
     4981 caacatgaga gcctcatgat cctcatactt gagagtacgc tctacatgat agcagtcctt
     5041 ataggtcagt tcaaacattt tggctctatc tttccgattt tgtaaagaca ccacgttcta
     5101 ccaagctatc catgaggaag tagaattttt cctgatgaat atggtggtct tctgatttga
     5161 aaatatcaac tagacgaagg ccaaacttgt cagtgatatt gattttagcc cctgtaagtt
     5221 ccttgttaat gatgattttg agttggaagc cttcaccgct gtttggcact ttttccaaaa
     5281 ggcgagtcag ttcatagtta ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga
     5341 attttttaac agaagggcta agagtgtaat cgtaacgaca attttttaac tgaatgattt
     5401 tttcaaatgc catatggcta acctccgata atttctttta aggtttttgc gagggtttgt
     5461 aggtcttcaa cggtattttg tggcgacaaa ctgatgcgaa gggattcctt caagcgttct
     5521 gaatttgcgc catgcatggc tttaagaaca tggctggatt ggacaacgcc tgcagtacag
     5581 gctgagccag tagagattga aattccagct aaatctagcc gaaggagtaa gaggtcattt
     5641 ttctgaccag gaaatccaat attgagaaca taagggagat gatgttttcc tctattcaag
     5701 taatactgaa tgccctccag ctctgccaga aaggcagttt ctagattttg tacatgttga
     5761 aaatgttctt cttgtttttc taggtcttct tttagggctg caaccatgcc tacgatggca
     5821 ggcagatttt cagttcctgc acgttttttc tgttcctgat ctccgccatg tagataggaa
     5881 tcaaagtcca tgctagatgc gtagagaaaa ccgattccct taggaccatg gaatttgtgg
     5941 gcagaagcag tgagaaaatc aatgcccaat tcttctgaat gaattgggat tttaccaata
     6001 gcctgaactg catcaacatg ataggcagca gggtgttgct tgagtatttg gccaatttca
     6061 gcgatgggaa gtaggtttcc tgtctcatta ttggcaaaca tagtagaaac caaaatcgta
     6121 tcgtcacgta aagccttttg aatttgctgg gctgtgattt cttgattttc tggctggata
     6181 atggttgctt caaacccaaa gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg
     6241 tgctcgatgg cagttgtgat gatatgtttt ccttgttctt ggtgacgaag acagtagcca
     6301 atgatggtag tattattgcc ttcagtccca ccagaagtga aaaagatatg ttgaggtttt
     6361 gtccttagta actgggctag ttcctgacgg gcttctcgca agagtttgcc agcttgacga
     6421 ccatgaccat gaatactaga aggatttccg tgggtttctt gcataacctt ggtcatagct
     6481 gaaatagcaa ctgctgacat aggagtcgtt gcagcattgt ccaaataaat caaagaatca
     6541 ccttatttct ttttattgta ggcaaagagt gggctgactg gttttctttc gtgaatacgg
     6601 acgatagcat caccaattaa ctcactagca gtgatgtagc atacattttt aggagttttt
     6661 tcttttgttg ctactgaatc agtcacaaga atttctttaa tattagtatt gtcaagaagc
     6721 tcagcagctc cctcgacgaa gagaccgtgg ctagaaacag cataaatttc tgtagctcct
     6781 tcacgttcaa cgattttaga agcttcagag aaggtacgtc ctgtatttaa aatatcatca
     6841 atcaagatag ctttcttacc ttcaacatca ccaataatat aaccttcgtt acgagttgca
     6901 tcgtcttgag ggtagtcgat aatggcgata ggagcatcaa gatattcagc caggctacgc
     6961 gcacgtttga cacctgaatt tttagggcta acgacaacaa catctgaacc aagcaatcct
     7021 ttatcgcagt aatgttttgc gaatagggga acagtgaaaa gattatccac tggaatatca
     7081 aagaaacctt gaacctgaac ggcatgcaaa tcaagagtca ggatacgatc aactccagcc
     7141 ttaaccagca tattggcaac tagttttgct gtaagtggct cacgaggaca agcaatgcgg
     7201 tcttgacgtg catagccaaa atatggaagg acaacgttga tactgtgggc acttgcacgc
     7261 acacaagcat cgaccatgat taacaattcc attaggtggt tgttgacagg gaaacttgtt
     7321 gattggatga tgtaaacatc ataaccacgg acactttctt cgatatttac ttggatttct
     7381 ccgtctgaaa attgacgtga tgatagtttt ccaagtggga caccaacagc ttgggcaatt
     7441 ttttgtgcaa tctcttggtt agagttgagt gcgaaaagtt tcatgttttt tctatctgac
     7501 attatagacc gtcctctgta aactttataa atcctagtta tatttacctt acatatatga
     7561 actgggattt gtgtattttt attttttcta ttttaccaaa aaatggagat tatttcagct
     7621 atttttcata cttttgacaa atcgaaccaa ttttgaagga gctttttggt aggaaatctg
     7681 atttttctct aaaaattgtc ggaaatcctg tttgccttgc tcatgatttt ccacttcaag
     7741 ctccaattcg taatctgtca tatcaaagta tcggctctga tccagtgcca tgagaccaat
     7801 agctgttttc atttcatagc gaagcgttgt tagacaacca agaacctgcc agttcttact
     7861 ttggatacca tgtttcgcca attcatccag tactagccct tgaggaagtt cttccttact
     7921 cagatagttc tcagcatctt ttagttgcaa tttttggttg tattccatgt ttccaacact
     7981 ctgcgggact ttgagtgtca actcagccca gtcttcaaag gttcgaatgc gcatagcgac
     8041 tttcttttct cgcagttcaa aatcaagcgt gtcgatgtag taatttgttt gaagaacagg
     8101 agtgacacct gtgaactggt cttttagacg attgtattca tcttttttca atagtgtttt
     8161 caattcaatt tctaaatgtt tcatttttct tacctttttt tatcgttgaa agcggattta
     8221 tggtataata agcattgtat ttattgtata tgaatctgga gaaaaaatca aagatatttt
     8281 tgacggataa tatgagaaca agggagaata tatgacctta gaatgggaag aatttctaga
     8341 tccttacatt caagctgttg gtgagttaaa gattaaactt cgtggtattc gtaagcaata
     8401 tcgtaagcaa aataagcatt ctccaattga gtttgtgacc ggtcgagtca agccaattga
     8461 gagcatcaaa gaaaaaatgg ctcgtcgtag cattacttat gcgaccttgg aacacgattt
     8521 gcaggatatt gctggcttac gtgtgatggt tcagtttgta gatgacgtca aggaagtagt
     8581 ggatattttg cacaagcgtc aggatatgcg aatcatacag gagcgagatt acattactca
     8641 tagaaaagca tcaggctatc gttcctatca tgtggtagta gaatatacgg ttgataccat
     8701 caatggagct aagactattt tggcagaaat tcaaattcgt actttggcca tgaatttctg
     8761 ggcaacgata gaacattctc tcaactacaa gtaccaaggg gatttcccag atgagattaa
     8821 gaagcgactg gaaattacag ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat
     8881 tcgtgatgat atccaagaag cccaggcact ttttgatcct ttgagtagaa aattaaatga
     8941 cggtgtagga aacagtgacg atacagatga agaatacagg taaacgaatt gatctgatag
     9001 ccaatagaaa accgcagagt caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa
     9061 atcagtttat actcaatgat accaatccgg atattgtcat ttccattggc ggggatggta
     9121 tgctcttgtc ggcctttcat aagtacgaaa atcagcttga caaggtccgc tttatcggtc
     9181 ttcatactgg acatttgggc ttctatacag attatcgtga ttttgagttg gacaagctag
     9241 tgactaattt gcagctagat actggggcaa gggtttctta ccctgttctg aatgtgaagg
     9301 tctttcttga aaatggtgaa gttaagattt tcagagcact caacgaagcc agcatccgca
     9361 ggtctgatcg aaccatggtg gcagatattg taataaatgg tgttcccttt gaacgttttc
     9421 gtggagacgg gctaacagtt tcgacaccga ctggtagtac tgcctataac aagtctcttg
     9481 gcggtgctgt tttacaccct accattgaag ctttgcaatt aacggaaatt gccagcctta
     9541 ataatcgtgt ttatcgaaca ctgggctctt ccattattgt gcctaagaag gataagattg
     9601 aacttattcc aacaagaaac gattatcata ctatttcggt tgacaatagc gtttattctt
     9661 tccgtaatat tgagcgtatt gagtatcaaa tcgaccatca taagattcac tttgtcgcga
     9721 ctcctagcca taccagtttc tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg
     9781 aatgaggttt gaatttatcg cagatgaaca tgtcaaggtt aagacctttt taaaaaagca
     9841 cgaggtttct aagggattgc tggctaagat taagtttcga ggtggagcga ttctggtcaa
     9901 taatcaaccg caaaatgcaa cgtatctatt ggacgttgga gactacgtta ccatttacat
     9961 tcccgctgag gaaggctttg aaaccttgga ggctattgag catccattag atattctcta
    10021 tgaggatgac cactttctag tcttgaataa accctatgga gtggcttcta ttcctagtgt
    10081 caatcactct aataccattg ccaattttat caagggttac tatgtcaagc aaaattatga
    10141 aaatcagcag gttcacattg ttaccagact agatagggac acttctggct tgatgctctt
    10201 tgccaagcac ggttatgccc atgcacgatt agacaagcag ttgcagaaga aatctatcga
    10261 gaaacgctac tttgctttgg ttaagggaga tggacatttg gagccagaag gggaaattat
    10321 tgctccgatt gcgcgtgatg aagattccat tattaccaga cgagtggcta aaggcggaaa
    10381 gtatgcccat acttcataca agattgtagc ttcttatgga aatattcact tggtctatat
    10441 tcacctgcac actggtcgaa cccatcaaat ccgagtccat ttttcttata tcggttttcc
    10501 tttgctggga gatgatttgt atggtggtag tctggaagat ggtattcaac gtcaggctct
    10561 gcattgccat tacctatcct tttatcatcc atttttagag caagacttgc agttagaaag
    10621 tcccttgccg gatgatttca gtaaccttat tacccagtta tcaactaata ctctataaaa
    10681 actgtctcag agtataatta ttatcttaaa ggagaaaact catggaagtt tttgaaagtc
    10741 tcaaagccaa ccttgttggt aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc
    10801 gtattcttca agcaacaaaa cgcttagtaa aagaaacaga agtgattcct gttttgcttg
    10861 gaaatcctga aaaaattaaa atttatcttg aaattgaagg aatcatggat ggttatgagg
    10921 tcatcgaccc tcaacattat cctcaatttg aagaaatggt ttctgccttg gtggagcgtc
    10981 gcaagggcaa aatgactgaa gaagatgtac gcaaggtttt ggttgaagat gtcaactact
    11041 ttggtgtgat gttggtttac ttgggcttgg ttgatggaat ggtgtcagga gcgattcact
    11101 caacagcttc aacagttcgt ccagctctac aaatcatcaa aactcgtcca aatgtaactc
    11161 gtacttcagg agccttcctc atggttcgtg gtacggaacg ttacctattt ggagactgtg
    11221 ccattaacat caatccagat gcagaagcct tggctgaaat tgccatcaac tcagcaatca
    11281 cagctaagat gtttggcatc gaacctaaaa ttgccatgtt gagctattct actaaaggtt
    11341 cagggtttgg tgaaagcgtt gataaggtcg ttgaagcaac taaaattgct cacgacttgc
    11401 gtcctgacct tgaaatcgat ggtgagttgc aatttgatgc agcctttgtt cctgaaactg
    11461 cagctctgaa agctcctgga agtacggtag ctggtcaagc aaatgtcttc atcttcccag
    11521 gtatcgaggc aggaaatatc ggttacaaga tggctgaacg cctgggtggc tttgcggctg
    11581 taggacctgt tttgcaaggt ttaaacaagc cagttaatga tctttctcgt ggatgtaatg
    11641 cagatgatgt ttacaagttg accctcatca cagcagctca agcagttcat caatagtgaa
    11701 aactataaag cgatatacta tgctatactg tagttatgaa actatgtacg aaaagcactg
    11761 ccattaattc ctgagaacta aattactgat tggtgtcaaa aaggaaaact tccaagcgat
    11821 gatatcctgt ctatacacga cctatagaaa tctgtaatat acatgtccgt aaaacgataa
    11881 attccctttt tgattttaaa tgagtatgaa aagagaattt tttcatgaga aaacgcataa
    11941 tattaagtgt cttgacacct gctattatgc gttttctggc tctttgtcaa ctgtagtggg
    12001 ttgaagaaaa gctaagctcg agaaaggaca aattttgtcc tttctttttt gatgttcaga
    12061 gcgataaaaa tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgtgcttg
    12121 ataagtttga tgagattatt ggtggcttcc agtttggcgt tggaataagg taattgaagg
    12181 gcgttgacga ttttctcttt atctttgagg aaggttttaa acagagtctg aaaaagaggt
    12241 ggaaaagcaa gagctgatag agattatagt ggtgtttcaa gtcttcggaa tagctcaaaa
    12301 gtttatctag aatttcttta ttagtcaagt gcatacgaaa agtagggcga taaaatcgtt
    12361 tatcactcag tttctgacta tcttgttgaa tgagctttca gtatcgcttg atagccttgt
    12421 attcatggga tttcggatga tggcttgtgt tctgctctca agaacagtta tgatattgag
    12481 cttatcaaag tcctgagcaa taaagctcat ctctatctcc cgattgaaac agtcactccc
    12541 cagactgttt caacgtccta ggacataatc tcaggaagac gcgaaaaatc atgctcaaag
    12601 tgaaaatcat tgatcttgcg aatgacagtt gaagttgaaa tagacaactg atgatcaatg
    12661 tcggtcatag aagtcttttc aattagcttc tgatcaatct tttggttgat gatacaagga
    12721 atttgatgat tcttcttgac gatagaagtc tcagcgacca tcattttaga acagtgatag
    12781 cacttgaaat gacgctttct aaggagaatt ctagtaggca taccagtcgt ttcaagataa
    12841 ggaattttag aaggtttttg aaagtcatat ttcttcaatt ggtttccgca ctcaggacaa
    12901 gatggagctt catagtccag tttggcgatg atttccttgt gtgtatcctt attgatgatg
    12961 tctaaaatct ggatattagg gtctttaatg tctagtaatt ttgtgataaa atgtaattgt
    13021 tccatatgat tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact
    13081 ttttttctac acaaaaatag gctccgtaat atccataggg gatttaccca ctacaaatat
    13141 tatagagccc aaagttttag gttgcttgat actatgcgtt ttttataatt tttgcacctt
    13201 tcttagcctt tgttatcgac aagcattgtt ctagctcctt gtttttagaa tggcaatttc
    13261 ccagcgaaag cacccagttt tttcttagta gtttcatcga tttgttcaag agcagagttg
    13321 atggcttgaa cggtcatatc agaaagagtc tcaaggtctt ctgggtcaac gacagctgga
    13381 ttgaaatcaa tgctgacaac tttcttatcg ccagttaagg ttgcttggac aagatcttga
    13441 gcagatttgc caacaaattg catagcagca agttcagctt ggctttgttc catttgtttt
    13501 tgaagttttt gtgcttgacg catcatgttt tgcatgttca tcataagatt tctaaagttc
    13561 ctttcatctc aaggggataa tccttgttgt taacaagtgc ctgattttct ctcctaattg
    13621 ttattagtag catagccatc aagtccaagt attgatttta ttataccatt tttttaagac
    13681 atagtctttt attggtgaga gttatttatg tcaaggagtg attagaaata aattaaaata
    13741 atgatttttg ctaagagggg ctctattcta gtttcatgga aatgatttta ctaaaggttc
    13801 gtatgctttg tttgcaaaca tgttacctct atctattttt ggataaatag ttgtcta
//
LOCUS       DAVMCN010000042        13494 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVMCN010000042 DAVMCN010000000
VERSION     DAVMCN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.043"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(1..1420)
                     /gene="pfbA"
                     /locus_tag="VYP85_001528"
                     /pseudo
     CDS             complement(1..1420)
                     /gene="pfbA"
                     /locus_tag="VYP85_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
     gene            complement(1732..2091)
                     /locus_tag="VYP85_001529"
     CDS             complement(1732..2091)
                     /locus_tag="VYP85_001529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882017.1"
                     /translation="MSTITYMPYSSILEALHLFLSRLNLAFIEGLFKKYSVLVSIRHM
                     SDIQVNIPGECLYDKVFVLSFIIYNISTNLNIVNGIFYIQAKKDSITFEWKAKEQTRK
                     LAIDSSKPCFEVVDIVK"
     gene            complement(2577..3803)
                     /locus_tag="VYP85_001530"
     CDS             complement(2577..3803)
                     /locus_tag="VYP85_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1882018.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(3846..4538)
                     /locus_tag="VYP85_001531"
     CDS             complement(3846..4538)
                     /locus_tag="VYP85_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1882019.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(4711..6462)
                     /locus_tag="VYP85_001532"
     CDS             complement(4711..6462)
                     /locus_tag="VYP85_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882020.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(6452..8197)
                     /locus_tag="VYP85_001533"
     CDS             complement(6452..8197)
                     /locus_tag="VYP85_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882021.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(8403..8699)
                     /locus_tag="VYP85_001534"
     CDS             complement(8403..8699)
                     /locus_tag="VYP85_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1882022.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(8852..9307)
                     /locus_tag="VYP85_001535"
                     /pseudo
     CDS             complement(8852..9307)
                     /locus_tag="VYP85_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            9441..10268
                     /gene="xth"
                     /locus_tag="VYP85_001536"
     CDS             9441..10268
                     /gene="xth"
                     /locus_tag="VYP85_001536"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1882023.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            10280..10531
                     /locus_tag="VYP85_001537"
     CDS             10280..10531
                     /locus_tag="VYP85_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1882024.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            10538..10666
                     /locus_tag="VYP85_001538"
     CDS             10538..10666
                     /locus_tag="VYP85_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1882025.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     regulatory      11049..11144
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            11544..12125
                     /locus_tag="VYP85_001539"
     CDS             11544..12125
                     /locus_tag="VYP85_001539"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1882026.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFSE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            12125..13387
                     /locus_tag="VYP85_001540"
     CDS             12125..13387
                     /locus_tag="VYP85_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1882027.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
BASE COUNT         3996 a         2907 c         2622 g         3969 t
ORIGIN      
        1 gtatcgcttt tgttttagga tcggcaatat taaatatatt ttcggcgata accacctgtt
       61 tatttaaatc taataggtct ttagtgtttt tatagctata agcatttact aaagctgctc
      121 cgctttctcg ataatgtaca ctctctcctt taactttctt atcaaagcga tttcctttga
      181 ttaatacatc agtgaatcct gtaaaacgta cacctgcata catcatgtta tcaaaatgat
      241 tatttaaaat tttaatatta gaggggttct gtgtcgacaa tgtttgatag tgtgtgccaa
      301 ttgctgttac taattcccca gatttatcac ttttgccaaa ataggaattt tgaatagtca
      361 cattttcaga ttttttccca tcatcattca aggcataagg aaaacctttt ctagttaatg
      421 gttcaatctg aatgctctcc ttacttatga tttacccatc cttcatcgtt ttgggtaagg
      481 cttgcccaag aaaacgagaa ttatcaacta atacattttt cgaacctgca atttgaatag
      541 catgcccttg ataactatcc ttgaatgtta cattttttat agttacgtta tttgaattcc
      601 caatagcaaa tgcacctgaa gaatttataa gtggtagatt ttttgcttta gttccttctt
      661 cattcaaagc accgttcata tcaatcgtac caccagaata actaatatct tctgttgggc
      721 cccattctac ttgcgcacca tcatccgtaa ataaacctgt cataaaaaca atggaagggt
      781 gattcttaat atttatacca tttagaattg tagctttctc attcaattct aagtgtgtat
      841 gactttttaa aaaaacaatt tcttttacta aataagttcc ttcaggaaaa tatacatttc
      901 ctccacctag cccttgagct gcagcatcta ttgcatcttg aattgcttgt cgatcatcat
      961 gaatcccatc acctaccgca ccataatctt ttacacttaa agcagtatct tcaaattctt
     1021 ttttgataat tctgtcactt ataacatctt ccttataact cttattttca ttagtagatg
     1081 ttactgtaga ttcaactgtt ctgttgtcta attgtgaatt ggaacgaata gtaccattag
     1141 agctgatact attaacactt aacgaattat ctaaaccatt agtggttgaa ttagaggcaa
     1201 tcatttcagc agaacgattc tgattaacag ttggtgaatt atctaaatca ttagtaatag
     1261 cattagaaga ctcttttgta gccatcggtg aagaactagt aacaacttca tccgataaaa
     1321 taccttggct tcccaaaatt gaaattgcca atagtaccga gcaagtcccc acctttaatt
     1381 tacgaatact gaatacctca ttaggaacaa aatatttcat cagaacctcc aattttttac
     1441 tatttttaac aattgattat tacttttctt aaaatagata gaatgacacc gctgtcatta
     1501 tctttatcat atattttcca aattgaattg tcaaggaata acacaagaaa atattaaaat
     1561 ttatactctt cggaaatctc ttcaaactag gtcagtgccg ccttgaccta agtctaggtt
     1621 actgacttgg tcagttctat agtagactga aactataata gtacacctct acttctaaaa
     1681 cattgttaga aatcgattta actgtcccga tcaatttgtc ctattcttgt ttcattttac
     1741 tatatctaca acctcaaagc agggttttga gctatctatg gccaacttcc tagtttgctc
     1801 tttagccttc cattcaaaag tgatgctatc tttcttagct tgaatataaa atatcccatt
     1861 tactatattt aaatttgttg atatgttgta aattataaat gaaagaacaa ataccttgtc
     1921 atacaagcat tcgccaggga tatttacctg aatatcgctc atatggcgga ttgaaactaa
     1981 aacactatat ttcttaaata gaccttctat aaaagctaga tttaacctcg ataaaaatag
     2041 atgcagtgct tctaaaatac tggaataggg catataggta atcgtagaca agtgttttat
     2101 agattgtctc gcgggagatc taatgatgta tagcaagcat cactaaacgt atagaatatt
     2161 tgtattatta taatatcaat atgctataaa ttctatcatg caaaagaatg actagaacat
     2221 gaaagacagg cacaaaactt tgaacaatat tctgaaaaca aaaaaagacg cgagtttcca
     2281 caatctcact catggaaact cacgtctttc aaaaaatagg gtgaattgaa aactagaaca
     2341 agacactaga ttttctaaat gatgtctagt aaggattcta aatgctacac caaattgctc
     2401 acatcttatt tcaaaccacg ggactcccac aagaaaggaa aatcctataa aaattctctc
     2461 tctgaggaga aagaggcctc aactacaggt gtaaactatt atcaattgaa aacaacagtt
     2521 tttacactca attagacttt ttagggacag gatcactttc gcttgactgt agtttgtcat
     2581 ttttttgata aagttagcac tttttcagaa actgttttga aagtctcaat gatatagtct
     2641 acttcttcat cgcttaattt agtatgaaga gggagggtaa tttcattctc aaagaaggca
     2701 taggccttag gatagttcgt catatcaaat ccaagattct tataggctgt caagagagga
     2761 agcggtttgt agtgaacatt acttgcaatt cctgctttag ccaattcttg gatgatgagg
     2821 ttgcgttctt ctaggcttgc tccttctaca cgggtgatgt agaggtggcg tgaagattcg
     2881 acagtttcag tcttgtgtgc caaaggatgg atgcgagaac ctgcaaaacc actatcatag
     2941 cggtccacaa tgtccttacg gcgttgcaac aaacttggat agcggtccaa ttgtaccaaa
     3001 ccaagtgaag ccatgatatc ggtcatgttg cacttatagg ctggtgtaac gatatcgtat
     3061 tcccatgacc ccagttgcat cttggcaaga gcatccttag tttgcccgtg aagggaaagg
     3121 atttggaatt ccttgtacat ctcttcgtca tcaatcactg gattggcttt ccaagtcgca
     3181 cttccacctt ctgccgttgt aaagttctta acggcatgga atgagaagga agtaaaatca
     3241 gcgatagaac cagaaggttg tcctttataa gtagatccca aagcgtgggc actatcagag
     3301 acaatgacaa tacggttaaa ggccttttgc cacttgcttg aagcggtaaa gaagtcacgt
     3361 tttttctcca cgacttggaa caaacggtca taatcgcaaa caatccctgc gagctctact
     3421 gggataatca ccttagtttt ctcagtgata gcttgctcaa gcaggtcata gtccatctca
     3481 aacgtatctg cttggatatc caccatgaca ggggttgctc ccacgtgcgt aatgacacta
     3541 catgaagccg tataggtcat ggctggaacg atgacttcat caccaggtcc cacttccaaa
     3601 acgcgtaaaa tcaactccag agcggctgtc gcagagttga gacaaacagt cttaggtgtc
     3661 tgtgtgtaaa gagacaagcg gcgctccagt tcttttgttt taggacctgt tgtgatccaa
     3721 ccagaacgca gggtatccgc tacttcagca atttctgctt ctgtgatatc aggcggtgaa
     3781 aatggaatat tgtaatttgg cattgatttg ctccttttat ctgtactcat tttcttatga
     3841 ctactttatt ttagtacctc aaacacggtt tgaaacatga ttttgatgtc cccaaagaaa
     3901 ctaaactctc ggagataggc gaggttatag cgcatctttt caggaagaac atgctccaca
     3961 taggcctgat caactgacag acctttctcc gtcatttgac tgatgatggt gtcctcatcc
     4021 ttgtagttga tgctggctgg agaggtaatt cctgcttgca agagcaaggt tgccatcatt
     4081 tcagggctat actgctctgt ataacgtggc acttcaggtc gtgtaccgac aaaggacatc
     4141 tcacctttaa ggacattgac caactgaggc agttcgtcca aacggacacg tcggatgaaa
     4201 tttccaacct tggtaatacg gctatcgtta gcagaagtca ccagacttcc ttttttatcc
     4261 gcatccgtca ccatggtacg gaacttccaa atcttgaacc gacggttgta ctgggtcaca
     4321 cgctcttgct tgtaaatcac tggccccttg ctatccaact tgatccaaat gctcaagatg
     4381 agaaagatgg gagaagttag aaccagtaag accaaggcca aaacccagtc caagcaacgc
     4441 ttgaaaatca gcgaaccctt ccttttagag acaagctggt agtaagactc aacctcgctt
     4501 gatttcattt ccacaggcaa gtcttcccat ttcagcatgc tgttctcctt tgtttttatt
     4561 atactatttg tcaacatttt tcattatacc acaaaatgga aaaggcggtg aaagaaatct
     4621 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     4681 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     4741 caaactatac atcttgtgat aggttcctcc cagagtcaag agttcctcat gggttccact
     4801 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     4861 gcggtgagcg atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     4921 caaactttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     4981 ctggctggcg actgttctag caaaggcaag aagctggcgc tgcccagtag agaagctcga
     5041 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     5101 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     5161 attggactta atagttccat gatagaggaa gggttcctgt aaaaccaaac cgatgttttt
     5221 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     5281 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     5341 acctacaaag gcaatggttt cacccttgtt aactgaaaag gaaatatcat ccagaatcgg
     5401 atgtttgcca tcatatgaga agcacacatg ttcaaaacgg atattgcctt cttggacttt
     5461 agcctgccca ttttcttgaa ggggctcata ggtcctctca tcgattaagg caaagacacg
     5521 gcctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     5581 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     5641 agaaagacca cgatagccaa aataggtcat caagacagca taacctagaa gtttcaacaa
     5701 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg cataggccaa
     5761 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     5821 aataatcctg attccctcga tattctctgc cagcttacta ttgatatctg acaagagact
     5881 tctggttttc tcgatgattt tcactgactt ttttcgatag agattgacca aaaggaaaat
     5941 caaaggaaga aagagcaaga ctaaagccgt caaacgaaaa tccagcacca acatggtata
     6001 aagggttgtc agaaagataa aaactgctga gataaagctg gataaaatcc cagaaaacat
     6061 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     6121 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatctcgac gaatatccct
     6181 aacaatactg taagacacgc gcgcaaagag aagattgcct acatactgaa ctacagtttg
     6241 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     6301 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     6361 cgctaggaga aaactgagtg ccaaaaaggt caggagtcca taaggcttga gataagacat
     6421 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     6481 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     6541 gcctgcctcg ttcgataatt tgaccatttt gcaggactaa aatcaaatct gcatggacaa
     6601 cagcactgag gcgatgggca gtgataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     6661 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     6721 agatatcagg gtctaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     6781 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     6841 cttggtaaac tcgggctagc ttagtagctt cctcgaccgc tgaaaggggc aagttaggat
     6901 tgccaaagcg gatattgtct aggattgaag ttgcaaagag aaactggtcc tgaggaacat
     6961 agcccatgag actgcgaagg tctgtcagac gatagtcccg aatatcgtga ccgtttagat
     7021 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     7081 cagagcctgt ctgcccaacc aagcccaggg tttgcccttt tgccaaacta aagtgaatat
     7141 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggtatactcc aaacgcccat
     7201 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     7261 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     7321 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttcccaactg
     7381 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     7441 caacaaacac gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     7501 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     7561 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     7621 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     7681 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     7741 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     7801 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     7861 tccgataggt ttgataaaag gctgatgaca tttttgtgaa atgcttaaac aagcgagacc
     7921 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     7981 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     8041 gggttaattg ccccgatgtg atggcatcaa tgacccgccc cataaccata ggaggaatga
     8101 gattgaggac ggaaaccaag accagggcca caatcccgac tagataacgg cgtttttcta
     8161 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     8221 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     8281 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     8341 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     8401 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     8461 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     8521 atcgattcca agacatctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     8581 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     8641 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     8701 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     8761 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagacc
     8821 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     8881 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     8941 gggcacgata atagcgttct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
     9001 taacatagac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
     9061 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
     9121 aaagcagagc taaataaggc cagagctgaa atcatgacca actcacgaaa ttcggttccc
     9181 tttttatcat ggtatgcctt aaaagcaaaa aaactgtcac agctaataga acaatcccaa
     9241 agccaaccat aataccattt tgctgaccga tttgactgag tacatagtca taagagtaga
     9301 atttcatgta ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta
     9361 atttttcaaa ctatacgttg gggaaataga tctttttttg gtataataaa atctataatc
     9421 tgaatgaaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
     9481 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
     9541 ctgaaaatgc tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
     9601 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt
     9661 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta
     9721 cgcctacgat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta
     9781 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
     9841 acggtctcaa acgcttggaa gaacgccaag tctgggatgt taaatatgct gagtatttgg
     9901 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
     9961 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    10021 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    10081 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    10141 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    10201 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    10261 acttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    10321 tatcgaacag tctcggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    10381 tccagaagaa aactttctct ttctttctct tgaagagtgt caactaatgt tagaggaggg
    10441 aacaaaggat caactagctg aactgaccta cccctttggt cgtggagtca atctctcctt
    10501 tggcataaag gatgtttcaa aactctatta aagagtgatg aaggcaaact atcctattta
    10561 tcgtcccttg accaaaagaa agtttcgtgt cagtgatccc tatatctatc ctcataaatt
    10621 tgcagttttg gatccaaatg gctatttttt aagatttagc gagtagaata ataaaaattg
    10681 ggaaaagtct ttaaagttag aaaaaggcat attgtcaggt gtttaaaaac ttgatagtat
    10741 gccttttatg atggaaaaat cttctaatac tcttcgaaaa tctcttcaag ccacatcaac
    10801 gtcgccttac cgtaggtata tgatactgac tctgtcaatt ctatccacaa cctcaaaaca
    10861 gtgatttgag gttgtggata gcttcctagt ttgctctttg attttcattt agtataaatg
    10921 ttagcttaca atgcagtttt tgttcactcc ttcttctgtt tgttcgtttt ttaaaccaaa
    10981 acactaacaa aatagttgat ttataaagtt atttagtgta aaataaaaac attggctcaa
    11041 acctatttaa aattgaatat cgttttactt gtttatgtcg tgaattggca cgacgtttct
    11101 acaaggtgcc ggaacaccta acaataagta agtcagcagt gagatatggc cgtttttgcc
    11161 atgcctattt gggggactta cttagagatt aagtaggtct tttttgaata tttttaatat
    11221 ttcccttaat tagtgcggac gggaggtgaa attatcctgt gaataatttc aggaatccag
    11281 ggaatttcat ccctaatttt tgagccccta gctctttcat ttctaggctt aggctaaaat
    11341 agttccccga actattttac tctcaaaaat cccgtcatag acaataacaa gattattgtc
    11401 tatgatacca ctacaacggg aaatatttga taagactcgc ttcgctcgta atagttttat
    11461 caaatatata gtattagcaa aagggatcac tatagaaaca tttaaacaac aagtaaatta
    11521 acttttagac tttaggaggt cttatgaaat tattagaaga gcgcatcctc aaggatgggc
    11581 atatcttggg tgataacatc ctcaaggtag attccttttt aacccaccaa gttgacttta
    11641 gcttgatgcg agagattggt aaggtttttt cggaaaaatt tgctgctgct ggcattacca
    11701 aggtcgtaac cattgaagcg tcgggtattg ccccagccgt ttttacagct gaagccttaa
    11761 acgttcccat gattttcgcc aaaaaagcta agaacatcac catgaacgaa ggcatcttaa
    11821 ctgctcaagt ctactccttt accaagcagg tgaccagcac tgtttctatc gctggaaaat
    11881 tcctctcacc agaggacaag gttttgatta tcgacgattt ccttgctaat ggccaagctg
    11941 ctaaaggctt gattcaaatc atcgaacagg ccggtgccac agtccaagct atcggtatcg
    12001 tgattgagaa atccttccaa gatggtcgtg atttgcttga aaaagcaggc taccctgtcc
    12061 tatcacttgc tcgcttggat cgttttgaaa atggtcaggt cgtatttaag gaggcagatc
    12121 tctaatgcaa actcaagaaa aacactcgca agcagccgtt ctgggcttgc agcacttact
    12181 agccatgtac tcaggatcta tcctggttcc catcatgatt gcgacagccc ttggctattc
    12241 agctgagcag ttgacctacc tgatttctac agatatcttc atgtgtgggg tggcaacctt
    12301 cctccaactc caactcaaca aatactttgg gattggactc ccagtcgttc ttggagttgc
    12361 attccagtcg gtcgctccct tgattatgat tgggcaaagc catggtagtg gcgctatgtt
    12421 tggtgccctt atcgcatctg ggatttacgt ggttcttgtt tcaggcatct tctcaaaagt
    12481 agccaatctc ttcccatcta tcgtaacagg atctgttatt accacgattg gtttaacctt
    12541 gatccctgtc gctattggaa atatgggaaa taacgttcca gagccaactg gtcaaagtct
    12601 cttgcttgca gctattactg ttctgattat cctcttgatc aacatcttta ccaaaggatt
    12661 tatcaagtct atctctattt tgattggtct ggttgttgga actgccattg ctgctactat
    12721 gggcttggtg gacttctctc ctgttgcggt agctccactt gtccatgtcc caactccact
    12781 ctactttggg atgccaacct ttgaaatctc atctattgcc atgatgtgta tcatcgcaac
    12841 ggtgtctatg gttgagtcaa ctggtgttta tctagccttg tctgatatca caaaagatcc
    12901 aatcgacagc acgcgccttc gcaacggtta ccgcgcagaa ggtttggccg tacttctcgg
    12961 aggaatcttt aacaccttcc cttacaccgg attttcacaa aacgttggtt tggttaaatt
    13021 gtcaggcatc aaaaaacgcc tgccaatcta ctacgcagct ggtttcctgg ttctccttgg
    13081 actgcttcct aagtttggtg cccttgccca aatcattcca agctccgtcc tcggcggtgc
    13141 catgctggtg atgtttggtt ttgtatctat tcaagggatg caaatcctag cccgagttga
    13201 ctttgctaac aatgaacaca acttccttat cgcagctgtt tcaatcgctg caggtgtcgg
    13261 tctcaacaac agtaatctct ttgtcagcat gccgacagcc ttccaaatgt tcttctcaaa
    13321 cggaatcgtc gtagccagcc tactcgccat tgtcctcaat gccgtattaa atcataaaaa
    13381 gaaataagaa aaagaggtgc gagcctcttt tttgtttatc acaaattgat tataaataca
    13441 atcaatccca attcccatct aattgaattg gacctatttc aaattcttta aaat
//
LOCUS       DAVMCN010000043        13362 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVMCN010000043 DAVMCN010000000
VERSION     DAVMCN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.044"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(113..748)
                     /locus_tag="VYP85_001541"
     CDS             complement(113..748)
                     /locus_tag="VYP85_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1882028.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(750..1577)
                     /locus_tag="VYP85_001542"
     CDS             complement(750..1577)
                     /locus_tag="VYP85_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1882029.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(1599..1935)
                     /locus_tag="VYP85_001543"
                     /pseudo
     CDS             complement(1599..1935)
                     /locus_tag="VYP85_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(1936..2652)
                     /locus_tag="VYP85_001544"
     CDS             complement(1936..2652)
                     /locus_tag="VYP85_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1882030.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRVQAPLVIKEVNGIKVALLAYSYGFNGIEQYISKEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSEMVEKDGDKKLIIY"
     gene            3165..3776
                     /locus_tag="VYP85_001545"
     CDS             3165..3776
                     /locus_tag="VYP85_001545"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1882031.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            3821..4549
                     /gene="rlmB"
                     /locus_tag="VYP85_001546"
     CDS             3821..4549
                     /gene="rlmB"
                     /locus_tag="VYP85_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1882032.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(4588..5499)
                     /gene="trxB"
                     /locus_tag="VYP85_001547"
     CDS             complement(4588..5499)
                     /gene="trxB"
                     /locus_tag="VYP85_001547"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1882033.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(5565..5789)
                     /locus_tag="VYP85_001548"
     CDS             complement(5565..5789)
                     /locus_tag="VYP85_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1882034.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(5867..6610)
                     /locus_tag="VYP85_001549"
     CDS             complement(5867..6610)
                     /locus_tag="VYP85_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1882035.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVAFIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(6610..7410)
                     /locus_tag="VYP85_001550"
     CDS             complement(6610..7410)
                     /locus_tag="VYP85_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1882036.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(7568..7924)
                     /locus_tag="VYP85_001551"
     CDS             complement(7568..7924)
                     /locus_tag="VYP85_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1882037.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(7937..8449)
                     /locus_tag="VYP85_001552"
     CDS             complement(7937..8449)
                     /locus_tag="VYP85_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1882038.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNK"
     gene            complement(8449..8943)
                     /locus_tag="VYP85_001553"
     CDS             complement(8449..8943)
                     /locus_tag="VYP85_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882039.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            9078..9524
                     /locus_tag="VYP85_001554"
     CDS             9078..9524
                     /locus_tag="VYP85_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1882040.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            9521..10168
                     /locus_tag="VYP85_001555"
     CDS             9521..10168
                     /locus_tag="VYP85_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1882041.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(10189..10770)
                     /gene="pdxT"
                     /locus_tag="VYP85_001556"
     CDS             complement(10189..10770)
                     /gene="pdxT"
                     /locus_tag="VYP85_001556"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1882042.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREGILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(10771..11646)
                     /gene="pdxS"
                     /locus_tag="VYP85_001557"
     CDS             complement(10771..11646)
                     /gene="pdxS"
                     /locus_tag="VYP85_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1882043.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(11798..13177)
                     /locus_tag="VYP85_001558"
     CDS             complement(11798..13177)
                     /locus_tag="VYP85_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1882044.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
BASE COUNT         3894 a         3101 c         2339 g         4028 t
ORIGIN      
        1 ataatccgta caatctgatt tacattcata aattcctccg tcacttttta ttttaaagga
       61 ttttagaatt ttttacaaga tattatgctc aaatttaaca ttatttagct atttagtaaa
      121 gatagtcttt caaggatttt gacaaagcct gataaccagc aatactgagg tgcagtccat
      181 cagttgtata ttcttttttg agttggcctg cttggtctgt caaacaatca aatactggca
      241 caaattccac ctgcatatag gcagatgcaa gctcttgata ggcttgattc cagttctgaa
      301 ttttttcatt cgagcggata tagactgcct gctggtactc ctctctctca ttgacaggca
      361 aaatggaaag caatttaatc tctgtcaatg gataatcgcg agcaacggat tgaatgatag
      421 cttcgagatt attgagagcc tcattcacag gaacatcctt tccgatatca tttgtcccaa
      481 tcagaagaaa aattttatct actgctccac catatagatg agcatcaagg ttctctagta
      541 acagtcctgt ctgatagcca cgaattcctc gattgacaat cgtctttgaa gtcccaaata
      601 gctcctgtag aggataatac tcgacaatgg aatccccaat aaaaagaatg tttggttcta
      661 caacagaaat gtgatttagg tgacgatact tagtttgaat tttttcttgt tcctttagga
      721 gccaattttc taataactgt actgccactt cattctcctt tttctaacca gttttccaaa
      781 acttgataaa ctcctccttg gctgttggct ggtgctagag cagtcgccac agctttggct
      841 ttctcatcag cattttccat cgcataggca attccagcca tttcaagcat ttcaacatca
      901 ttttcactat caccaaaagc catgatttct tgggatttca agtcccagcg cttgagtaat
      961 tcctccaagc cccatgcttt atgaatccca gcttggagga tatcaatgca accatagcca
     1021 ctggatacag ctcggacacg gccatcaaag agagcattga tttcttccaa aaccgaactc
     1081 aaacgttcct caccaacaac catgctcatc ttgagcacac caccaaagag gtcagatgtt
     1141 aattcatcca caaattgcat ccgttggtag aatttttcaa tcatttctgg agtcataaaa
     1201 ctttcaagat ctgtaaaaat cgtaccttcc ttgacaaaat cacccttcat ccccgttaca
     1261 acaaactggt cctgacacgc tcgacccttg aaatgagcca aagccttgtt gacaatggcg
     1321 tcatcccatg tctgagcctg aatcaattca ttgttttcaa aaatacgagc gccattagca
     1381 acaaccagaa ccactcgatc caccaaggga ctcagtagtt gtctcatgcg gtgaatttca
     1441 ttgcccgtcg caatgacaaa acgaatgccc ctttgatcca actgatctaa aatcttttcc
     1501 aatcgtggga gatcaagctg acccctagca tccagcaagg tcccatccat atctgtcgca
     1561 attaccttaa tcatcattta ctttcctctg gattcaagct aataccactt caatcccaca
     1621 tgttcattca tttctttata ggctgtatca attcgttcct tagtcgcttc atctaactgg
     1681 tcacgatgac tgccacccct ctataaaatc ttccaaaata taagtttggt aatgatacaa
     1741 gggatatcct tctggtgaaa aggttccctt tggtgttcga ttgacccaag taggatgagc
     1801 tttagctgtt ccgatagttg tttttccatc cttcttcttg atggtgacat ccatgagaac
     1861 accacgttca gtccacttag cattctcttc atctcccata gattcaattc gttgattgga
     1921 aatgaagttc cccatttaat agataatgag tttcttatct ccatcttttt caaccatttc
     1981 agatggttca acaacgtgag gatgccctcc aaagataata tccgctcccc aatcgatcat
     2041 cttgtgataa agagcttttt gttcttcagt tggttccaat cgatactcaa cacccatctg
     2101 aagcatgata atggtgatat ctgcttcctt ctctgcccgt tcaatttcag ccttcatctt
     2161 atcttcgttt aaatctgaaa gataacgatt atagtcttcc ttagaaatat actgctcaat
     2221 tccattgaaa ccataggaat aggctaacaa tgcaaccttg ataccattca cttccttaat
     2281 gaccagcgga gcctgaacac gtggttcgtg cgtataaact ccgattggag tgattccagc
     2341 tttctcaata atatcggccg ttgaaataac tccctcaatt tgcgaatcca aaatatgatt
     2401 atgagctaaa tccagcacat gataacctgc ctccttaata gcatccataa cttcaacagg
     2461 agcattaaag agaagataac ccgctaaata atgatcctta ttaatggttc cttcaaaatc
     2521 accaatagct aaatctgctt gcttgagcca aggagtcaca tactcaaaat tttcatgaaa
     2581 gtcataggta ccgtcttctt ttttagctga aaagaaaagt ccatcgtggt agagcaaatc
     2641 cccgtgggcc ataattctgg cagttttttc ctcttcctac tcctgagact tttgcttagt
     2701 cccctcttga gaaatagtat ctcgtttttg actagtcaag ggattccttg gaagctttca
     2761 aacaacaaga ccaagcccat tgataaacca actgctagca agagtatcgc cacaaatccc
     2821 ttattgctcc acttgcgata actcctaaaa agtttaccaa gcccttcata aaacgaaaag
     2881 ctaaaccacc ctgatttcga ttttgtcttc tttgtatctt cgttctccct actttcttat
     2941 gcaagccttt tctttttatt atatcacaga taagtatttc tttcacaatt gaattgaact
     3001 tcctatctat tttctataaa tcctaaatgc cataatgctt tcaattcttg tcattttgtg
     3061 atatcatgta gaggaaatga actaatccac agtggcttat tccaagtata ccacttgggc
     3121 tttggcagta gctaactgca ctaaacataa tataaggaga gaaaatgtct gcaatagaac
     3181 gtattacaaa agctgctcac ttaattgata tgaacgatat tatccgtgaa gggaatccta
     3241 ctctacgcac ggttgctgag gaagtcactt tccccctatc tgaccaggaa atcatcctag
     3301 gcgaaaagat gatgcaattc cttaaacatt cccaagatcc tgtcatggct gaaaaaatgg
     3361 gactccgcgg tggtgttgga ctggctgctc cccagttaga tatctcaaaa cgcattatcg
     3421 ctgttttggt acctaatatt gttgaagaag gcgaaactcc acaggaagcc tacgatttgg
     3481 aagccattat gtacaatcca aaaatcgtct ctcactctgt tcaagatgct gctcttggcg
     3541 aaggagaagg ttgcctgtct gttgaccgta acgtgcctgg ctatgttgtt cgccatgccc
     3601 gcgttactgt tgactacttt gacaaagatg gagaaaaaca ccgtatcaaa ctcaaaggct
     3661 acaactccat tgttgttcag catgaaattg accacattaa cggtatcatg ttttacgatc
     3721 gcatcaatga aaaagaccca tttgcagtta aagatggttt actgattctt gaataaagaa
     3781 aatcccgttg caagacgggg ttttgtgtta taatagaggc atgaaaacaa atgatattgt
     3841 ctatggtgtc cacgccgtta ccgaagccct ccttgcaaat acaggaaaca aactctacct
     3901 ccaagaagat ctccgaggta agaatgttga gaaagtcaag gaactagcta cagaaaagaa
     3961 ggtgtccatt tcttggacat caaaaaaatc tctctctgag atgactgaag gtgctgttca
     4021 tcaaggtttt gttctacgag tgtctgaatt tgcctatagc gagctagatt acatccttgc
     4081 aaaaacacgc caagaagaaa atccacttct attgattcta gatggtctaa ctgatcccca
     4141 taatctgggt tctatcttgc gaacagccga tgcgaccaat gtttcaggtg tcatcattcc
     4201 caagcaccgt gctgtcggag taactcctgt cgttgccaaa acagccacag gtgctattga
     4261 acacgttcca attgcccgag tgacaaacct cagtcaaacc ttagataaac tcaaggatga
     4321 aggcttctgg acctttggaa cggatatgaa cggtactcct tgccacaagt ggaatacaaa
     4381 agggaaaatc gccctcatca tcggaaatga aggaaaaggc atctctagca acatcaaaaa
     4441 acaggtcgat gaaatgatta ccattccgat gaatggacat gttcaaagcc tcaatgccag
     4501 tgttgctgca gccattctca tgtacgaagt tttccgaaat agactataaa aaagtttcca
     4561 gtcatctgat tggaaacttt tttatgatta actatgttct gtgataaact tgtaggcttc
     4621 ttgaccagcg atagctccat ctccaactgc tgttgttact tggcgaaggt ctttcaagcg
     4681 aacatctcca actgcaaaga taccgtcgac tgcagttttc atgtggttat ctgtcacaat
     4741 ccatcctgcc tgatcttgga tattcaattc tttaacaaaa tcgctaagag ggtccaatcc
     4801 aacatagata aagacaccac cgaaggcttg ttctgtcact tgacctgttt tcacattttc
     4861 aaatacgact gattctactc ggttttcacc cttgattttc cttactacag aatcccatat
     4921 aaagctgatt ttctcattgg caaaggcgcg atcttgtaaa accttttggg cacgaagttg
     4981 gtcacgacgg tgaacaatgg taacagtctt agcaaaacga gtcaagaaga gggcttcttc
     5041 aacagctgaa tctccaccac caactaccaa taaatcttgg tcacggaaga aagcaccatc
     5101 acacacagca cagtaagaaa caccacgact gttcagttct tcttctccag gcactcccaa
     5161 aggacggtgt ttagaaccag ttgctacgat aactgtacgt gtttcatatg tttggtcatc
     5221 agtcatcact ttcttaaaat caccatggtc ttcgacattt tcaacataac cataaatgtg
     5281 ctccacacca agattttcaa gtggttcaaa catcttttca gccaattcag gtccactaat
     5341 attagcgtat cctgggtaat tttcgatatc agatgtatta ttcatctgac cacctggcag
     5401 accaccttca atcaaagcta cttttagatt gcttcgagca gcatacaagg ccgcagtcat
     5461 ccctgcaggt ccagcaccga taataatagt atcgtacata tagattcctt ctttcttgtt
     5521 gtaactatct ttattctaac tctttcttgt caatcacgca aggattatgc cttgaaaaca
     5581 agaattaaac tcataaccgc aaaggataat actgggacaa ccaagactcc aatcataatc
     5641 atatcataga gatgggcttg gcgagccttg gctgtcttat caactcccga catggctctc
     5701 agaccaatcc aaatccctaa aaaaatcaga acaaggatgg tggtcaatat caaactctcg
     5761 aaatataaag aaaatagttg cagtagcatg atttctctca tttctatctt ttttaaagag
     5821 taaactcagc tagtccaact aactgagttt tcctttatct attatatcaa atataagtcc
     5881 gtttgtaact agcgaagaat tcttttgtcc gctcttcttt aggggtgtgg ataatctcat
     5941 ccggagttcc agactcgatg attttcccct tatctaagaa gagaatctta tccgcaactt
     6001 gggctacaaa ggacatgtca tgactgacca aaatcatggt ctgacctgac ttagcagcat
     6061 ctgcaataga cttttctact tcaccgacca attctgggtc aagggctgaa gttggttcgt
     6121 ctaagagcaa aacatctggt ttcatagcaa gcgcacgcgc tagggcaacc cgttgcttct
     6181 gtccacctga taaatggcga ggataatggt tttcacggtc cgaaagccca accttagcca
     6241 actcttcctt ggcaatctta gtcgcttctt ggtcagataa tttcttgaca acaaccaagc
     6301 cttctttcac attatcaagt gctgttcggc gttcaaacaa attaaactgt tggaaaacca
     6361 tagacaactt acggcgtagg gcaaggattt cttcttgagt aattttagaa aaatcaactg
     6421 aaaaaccatc aatctgaata gagccactgt caggtgtttc aagataattg agactgcgaa
     6481 gaaaggttga ttttccagct cctgaagaac caataaaggc tacaacttcc cctttttgaa
     6541 tatccaagtc cagatgatcc aagacagtct gtcctgaaaa ggatttgctt aaattcgaaa
     6601 tcttaatcat taacgaaggt ctcctttcac atctgtttgc actgtatcag gtgcagaaat
     6661 agccattttt ctctcgatga aacgaccgag gctttcaatt ccgatattga ctacccaata
     6721 aacaagggca acggagatga agcgttcaaa atagcgataa tcagctccac ctagaatctg
     6781 agcttgggca aagacttcca caacacccgc actaaaagct agagatgttc ccttggtcaa
     6841 accgatgagg gaattaatca aggttggagt agctaccacc gctgcattag gaataatcac
     6901 tcgtcgataa acttgcgctc gggtcatacc cagactgcgt gccgcctcaa tctcaccagg
     6961 attaactgag agaatggctg cacgaatggt ttcactagca taagctgcct cattaaaggc
     7021 aaaggcgaca atcgcaaaag ctgcagctgg aatcgcattg atattgagac cagttcccca
     7081 ttgctgattg agggctttca aagccaaagg gattccgtag taggtcaaca tgagttgcac
     7141 caaaatcggt gtccctttta agaaactaac aaagaaggcc tgcaagggat ataaaatctt
     7201 gacacgattg atcttcacaa tggcaaaaag aagcgccaaa accaaaccaa aaagggcacc
     7261 accaattgtc aacataattg ttgttggaag ttgttggaca attctaggga ttccatcaaa
     7321 gaccgaacgt aggctaaaca gcttgccatc cggaatcaat tgcatcaagt tttggtacca
     7381 atctgatgct aaaatcgttg taacattcat aaaaacatcc tcttctgata atgattcatt
     7441 ctaccatgct tctgccgtca atgaaattat ttgctacggt cagatacaga ctttgtctac
     7501 ctactagttt atcatacttt gaaacaggga agttatatat tttatctatc aaagagatag
     7561 ataaaaacta tttcagtccc agttcttcat aagattttcg ataaccgatt tgcttaacag
     7621 ttccattttc tactaaaatg ggccgtttta acaacatacc gtcacttgct aacaactcag
     7681 ccgcttcttg gtttgacaaa cttcctacct tatcttttag ccctaattca cggtatttga
     7741 ttccactggt gttgaaaaat tgcttcaatt caaatcctga ggtttctagc caattcaaaa
     7801 tgacttcttg gctaggtgtt tcttccacga tatggacggc tttatagtcc acacctaatt
     7861 gatttaattc ttgttttgct tttttacaag ttgaacattt ggggtattcg ataaattcta
     7921 acatgtgctt ctccttctat ttgtttctat ctttaaaatc tactccttca tgctccaaga
     7981 gccaagcttt cttttccact cctgcagcat agcctgtcag acgcttgcct gctcccaaca
     8041 cacgatgaca aggtactagg atagaccaag gattgcgtcc cactgctcca ccaattgctt
     8101 gagcagaagc cacttgcagg tcttgagcaa tttgtccata ggtcactgtc tgaccataag
     8161 gaattccctg taaataggac caaactctct tttcaaaatt cgttccaatt ggcgccaaga
     8221 gcaagttgga taaatcctga ggctcgcctt taaagtaatc atctaagcaa gcaataactg
     8281 ggtctaaaat aggatgacta acaacttctt ctatcgtttc atctcctagt cccctctcaa
     8341 aatgcttctg ctcctgaacc caaattccat acaaataatg gtcatcagct acaagtgata
     8401 gaataccaat tggtgaggag tagaggattt ttacatactt cttttgcatt atttctttaa
     8461 tttttgatag gccaagcgtt cgccatctac tggcacctta ccaacttgtt taaaaccaag
     8521 tttttcaaaa atatgttgca taaccttgtt ttcagcatgc gtatctgagc gaaaatcaag
     8581 ataatcaaaa ccttcaatca agccctctaa gaaggtttga gcaactcctt ttccctgcac
     8641 atctgctgcc acagcaatac ggtgaaagac tagatactct gactctccag cttgccagtt
     8701 tccctcataa atagcttcat aggcctcctc tggactcttg gtcacagcag cataggctag
     8761 cagttctccc tcttccaagg ctacgtaggc ttgccctgag atgatatcat cgataataac
     8821 atctgcattt ggatagccat tttgccactg gttactacca gcatctgcta aacatttttt
     8881 ggcatcctct atcacctgca tgatggcatc tacttcattt ggaaaagcta aacgaatttc
     8941 catctttttt cctcatttct gactagtttc tcccatcata gcataattta agtctttcta
     9001 caagcagtta aaacttgact ttgtattttt gttattttat aatctagtta tcaaaactat
     9061 ataaaaagga gttgaaaatg aaaactacct tttcctaccc aaaatgggca gaaattccaa
     9121 acattaacct ctatctggac caggttttgc tctatgtcaa tcaggtctgc gcccctatct
     9181 ctcctaataa agacaaaggc ctaacagcat ctatggtcaa caattatgtg aaaaatggtt
     9241 acctgacaaa gcctgacaaa aaaaaatacc aacgccaaca gattgcccgt ttgattgcta
     9301 tcacaaccct caagtctgta ttttctattc aagaaatagc ccagacactt aatactctac
     9361 aaactcaagc aagttcagac caactctacg atgcttttgt ggactacatg aaccaaggaa
     9421 ttgacccagc taaccctatt atccaaacca gctgccaaac cgttaaactc tatcatcaaa
     9481 ctctagactt aatcgatcat actcaagagg aggtaatcca atgaacacta gtcttaaact
     9541 cagcaaacaa ctcagttttg gagaggagat tgctaatagc gtgacccatg ctgtgggtgc
     9601 agtcatcatg cttatcttgc tgcctatttc atccatctat agttatgaag cacacggatt
     9661 tttatcctct atcggcgttt ccattttcgt catcagtctc tttctcatgt tcctatcatc
     9721 caccatttat cactctatgg cctatggttc gacccacaaa tatgttttgc gaatcattga
     9781 ccattctatg atttacgttg ccattgccgg ctcatacacg cccgttgtct tgaccttgat
     9841 gaataactgg tttggctatc tgattattgt catccaatgg ggaacgacca tctttggtat
     9901 tctctataaa atctttgcta aaaaggtcaa tgagaaattt agccttgctc tttacctgat
     9961 tatgggctgg ttggttctgg ctatcattcc tgccattatc agtcaaacga cacccgtttt
    10021 ctggagtctc atggtaactg gcggactctg ttatacagtt ggagctggat tttatgccaa
    10081 gaaaaaacct tatttccaca tgatttggca tctctttatc ctagctgcgt ccgcacttca
    10141 atacatcgct attgtttatt acatgtaaaa aagttgagaa attcaatctc aacttttttc
    10201 tttacacata ttgataaagt actggtgcaa gcgcacatca tcagtcaatt ctggatgaaa
    10261 agaacttacc aacatatttt tttcttgggc tgcaacaatt tgattgttca ctgttgctag
    10321 aatttctaca ccctcaccaa cactactgat aatcggacca cggataaagg tcattggaat
    10381 cttgccaact cccttacatt ctgcttccgt gtagaaactt cctaattggc gcccataagc
    10441 attacgctcg accaccatat ccatagttcc tagatgactc tctttctgag aagtgatttc
    10501 cttagccagc aaaattaagc ccgcacaggt cccaaacact ggtaagccag atagaatgcc
    10561 ttctcggatg ggaagtagca tgttctggtc acgtaagagc ttgcccatgg ttgtagactc
    10621 accaccaggc aaaatcaaac ccgacaagtc actctgatct tgctgaaaat catctagatt
    10681 tctgagttct acactctcga cacctaattg atctagcact tttgcatgtt ctgcaaaggc
    10741 cccttgcaag gccaatattc cgattttcat ctattttcct cgttcagcca tgagaatttg
    10801 gatttcattt tcattaatac caaccatggc ttctcctaaa tcttcagaga tttgagctag
    10861 gatttgagga ttacggaagt tagtcacagc cttaacaatg gcactcgctc gtttaacagg
    10921 atctcctgac ttgaaaatac ctgaaccgac aaagaccccc tctgccccta attgcatcat
    10981 taacgcagca tctgctggcg ttgcaacacc tccagcagcg aaatttacaa ctggcaattt
    11041 tccatgttca tgaacatatt ggaccaattc tacagggact tgcaaatcct tggcagcaac
    11101 ataaagctcg tcctcacgta agttttgaat gcggcgaatt tcctgattca tcatacgcat
    11161 atgacgaaca gcttggacga tatcccctgt ccctggttct cctttggtac gaatcatgga
    11221 agcaccttca gcgatacgac gcaaggcttc acccaaatcc ttagcaccac agacaaaagg
    11281 aacttggaat tctttcttgt ccacatggaa acggtcatca gctggagata gaacttcact
    11341 ctcgtcgata taatcaattt caatagcctc taaaatctga gcttcaacaa aatgcccgat
    11401 tctgacctta gccattactg gaatactaac tgcttcttgg atttccttaa tcatctttgg
    11461 gtcgctcatg cgggaaactc ctccagctgc acgaatatca gccggaattc gttccaaggc
    11521 catcacagct gccgcaccag cagcttctgc gatacgagcc tgttcaggat tctgcacatc
    11581 cataataaca ccacccttga gcatctgtgc caagttttta tttagttcat aacgattttc
    11641 agtcatttgt tttatcctca tcatttgtat tggtagctac cttttcattt taagtcagaa
    11701 cagaatgaag cacaagataa aaaaactata attgtatggg gacagattag ctaaaaacta
    11761 tctgacctta acttaaggcc agatagctca ttcattttta tttttcagcc gtaagggcag
    11821 ccattgtgat gtagttgtat ggtttgttga agtgtggcaa gaagaagagg tctgtcaatg
    11881 ccaatttatc aattgtcaca tgctcttgga tagcaagtga gaacatgtgg attcccatgc
    11941 taattgcaat atcatgtgaa accatttggg caccaagaat ttcacggcta tctttgtcaa
    12001 agacaatctt aattgctact tcatggttgt catgtttcat gaattctggt ttttgaagat
    12061 cgttaaagcc tgtttcagtt gcgttgtaac cagcagcttt cgctttttca agagtcaaac
    12121 cagttgaaac catgtgaaga ccgtagattg agataccatt tgaaccttga acaccgattc
    12181 cttccaattc atgtccacaa gcgttgtagg caccaacgat accagtgcga acagcatttg
    12241 aagcaagagc gatatagctt gtatctttac gagcattgtc ataaacagtc gcacagtcac
    12301 caacagcgta aacgcctggg atagatgttt cttgtttctt gtctacaagg aaggcaccgt
    12361 tgcggaagag ttcgatctta ccatctgcaa gggctgtgtt tggacggaaa ccaactgcaa
    12421 ggataaccat atccacgtca aagctttctt tgtcagtaat caagcgttca actttaccgt
    12481 caccttcgat tgctttaaca gtttgaccta gagccaagcg gatgttgtga tcttccaagt
    12541 tcttcgccat catttgtgtg aagtctttgt catagtaacc gttcaagaca gtatcaacga
    12601 tatcaacaag gacaacttct tttccaagac gttcaaaggc ttcagcaagt tcaacaccga
    12661 tgtaaccacc accaacaacg gcgatacggt cgaggtgttg gctcttgtca gaaagtttat
    12721 tgataacttc ttcagcattt tggtacaatt tcacgaattg tacgttttca agagttgctt
    12781 taaattcgcg gtttccttta acaatttcaa caccttcgat tggtggcaag attggtgtag
    12841 aacctgtagc gaaaatcaat ttttcgtatg attctttgtg ctcttttcct tcaacttccg
    12901 ctgtaactac tttgttatca tagtcgattg aaagaacagg tgagttcatg taaactttag
    12961 cacctttagc ttccaatttt tctttatcag aatagaacaa gccttcagca ccgtcaattt
    13021 gttcaccaat ccaaagagcc attccacatc ctaggaaaga gatgttagag ttttggtcaa
    13081 atacaacaat ttcgttctca tttccaaaat tatccaacat ggtattgata catgctgtac
    13141 cagcgtggtt agcaccgact acaacgattt tactcataaa aatttcctgc cttcattcta
    13201 aatttacctt actagtatac catttaccgt tagcgtttac aaggggggta ctattatttc
    13261 agcatttttt atcaaaaata attccccatt tatcctgttt tcaagcctca tgaattttat
    13321 gagtatattt cttgactttt tccaaatttt gtttttgaaa at
//
LOCUS       DAVMCN010000044        13273 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVMCN010000044 DAVMCN010000000
VERSION     DAVMCN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.045"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            96..5666
                     /gene="zmpC"
                     /locus_tag="VYP85_001559"
     CDS             96..5666
                     /gene="zmpC"
                     /locus_tag="VYP85_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HEV1882045.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            6022..6876
                     /locus_tag="VYP85_001560"
     CDS             6022..6876
                     /locus_tag="VYP85_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1882046.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            6982..7539
                     /locus_tag="VYP85_001561"
     CDS             6982..7539
                     /locus_tag="VYP85_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEV1882047.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            7756..8520
                     /locus_tag="VYP85_001562"
     CDS             7756..8520
                     /locus_tag="VYP85_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1882048.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(8760..9002)
                     /locus_tag="VYP85_001563"
     CDS             complement(8760..9002)
                     /locus_tag="VYP85_001563"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882049.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            9220..10599
                     /locus_tag="VYP85_001564"
     CDS             9220..10599
                     /locus_tag="VYP85_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1882050.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            10613..11278
                     /locus_tag="VYP85_001565"
     CDS             10613..11278
                     /locus_tag="VYP85_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1882051.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            11588..11761
                     /locus_tag="VYP85_001566"
     CDS             11588..11761
                     /locus_tag="VYP85_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1882052.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGWDQVGNFSKGQYIMMHS
                     LIYRTDLLRASQF"
     gene            11828..12238
                     /locus_tag="VYP85_001567"
     CDS             11828..12238
                     /locus_tag="VYP85_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1882053.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEQLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            12354..>13273
                     /gene="pavB"
                     /locus_tag="VYP85_001568"
     CDS             12354..>13273
                     /gene="pavB"
                     /locus_tag="VYP85_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1882054.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVK"
BASE COUNT         4252 a         2316 c         2938 g         3767 t
ORIGIN      
        1 actcagaaaa ttccatacta tattattttt atgtttatac ttttatgcta taaaatatag
       61 attgatataa agaatataga aaaagcgagg ttaatatgag ccgaaaaagc attggtgaga
      121 aacgccatag tttctcgatg agaaagttgt cagtgggatt ggtatcagtt actgtatcta
      181 gtttcttttt gatgagtcaa gggattcaat cggtatcggc cgataatatg gaaagtccaa
      241 ttcattataa gtatatgaca gagggtaaat tgacagacga ggaaaaatcc ttgctggtag
      301 aggcccttcc acaactggct gaagaatcag atgatactta ttacttggtt tatagatctc
      361 aacagttttt accgaataca ggttttaacc caactgttgg tactttcctt tttactgcag
      421 gattgagctt gttagtttta ttggtttcta aaagggaaaa tggaaagaaa cgacttgttc
      481 attttctgct gttgactagc atgggagttc aattgttgcc ggccagtgct tttgggttga
      541 ccagccagat tttatctgcc tataatagtc agctttctat cggagtcggg gaacatttac
      601 cagagcctct gaaaatcgaa ggttatcaat atattggtta tatcaaaact aagaaacagg
      661 ataatacaga gctttcaagg acagttgatg ggaaatactc tgctcaaaga gatagtcaac
      721 caaactctac aaaaacatca gatgtagttc attcagctga tttagaatgg aaccaaggac
      781 aggggaaggt tagtttacaa ggtgaagcat caggggatga tggactttca gaaaaatctt
      841 ctatagcagc agacaatcta tcttctaatg attcattcgc aagtcaagtt gagcagaatc
      901 cggatcacaa aggagaatct gtagttcgac caacagtgcc agaacaagga aatcctgtgt
      961 ctgctacaac ggtgcagagt gcggaagagg aagtattggc gacgacaaat gatcgaccag
     1021 agtataaact tccattggaa accaaaggca cgcaagaacc cggtcatgag ggtgaagccg
     1081 cagtccgtga agacttacca gtctacacta agccactaga aaccaaaggt acacaaggac
     1141 ccggacatga aggtgaagct gcagttcgcg aggaagaacc agcttacaca gaaccgttag
     1201 caacgaaagg cacgcaagag ccaggtcatg agggcaaagc tacagtccgc gaagagactc
     1261 tagagtacac ggaaccggta gcgacaaaag gcacacaaga acccgaacat gagggcgaag
     1321 cggcagtaga agaagaactt ccggctttag aggtcactac acgaaataga acggaaatcc
     1381 agaatattcc ttatacaaca gaagaaattc aggatccaac acttctgaaa aatcgtcgta
     1441 agattgaacg acaagggcaa gcagggacac gtacaattca atatgaagac tacatcgtaa
     1501 atggtaatgt cgtagaaact aaagaagtgt cacgaactga agtagctccg gtcaacgaag
     1561 tcgttaaagt aggaacactt gtgaaagtta aacctacagt agaaattaca aacttaacaa
     1621 aagttgagaa caaaaaatct ataactgtaa gttataactt aatagacact acctcagcat
     1681 atgtttctgc aaaaacgcaa gttttccatg gagacaagct agttaaagag gtggatatag
     1741 aaaatcctgc caaagagcaa gtaatatcag gtttagatta ctacacaccg tatacagtta
     1801 aaacacacct aacttataat ttgggtgaaa ataatgagga aaatactgaa acatcaactc
     1861 aagatttcca attagagtat aagaaaatag agattaaaga tattgattca gtagaattat
     1921 acggtaaaga aaatgatcgt tatcgtagat atttaagtct aagtgaagcg ccgactgata
     1981 cggctaaata ctttgtaaaa gtgaaatcag atcgcttcaa agaaatgtac ctacctgtaa
     2041 aatctattac agaaaatacg gatggaacgt ataaagtgac ggtagccgtt gatcaacttg
     2101 tcgaagaagg tacagacggt tacaaagatg attacacatt tactgtagct aaatctaaag
     2161 cagagcaacc aggagtttac acatccttta aacagctggt aacagccatg caaagcaatc
     2221 tgtctggtgt ctatacattg gcttcagata tgaccgcaga tgaggtgagc ttaggcgata
     2281 agcagacaag ttatctcaca ggtgcattta cagggagctt gatcggttct gatggaacaa
     2341 aatcgtatgc catttatgat ttgaaaaaac cattatttga tacattaaat ggtgctacag
     2401 ttagagattt ggatattaaa actgtttctg ctgatagtaa agaaaatgtc gcagcgctgg
     2461 cgaaggcagc gaatagcgcg aatattaata atgttgcagt agaaggaaaa atctcaggtg
     2521 cgaaatctgt tgcgggatta gtagcgagcg caacaaatac agtgatagaa aacagctcgt
     2581 ttacagggaa acttatcgca aatcaccagg acagtaataa aaatgatact ggaggaatag
     2641 taggtaatat aacaggaaat agttcgagag ttaataaagt tagggtagat gccttaatct
     2701 ctactaatgc acgcaataat aaccaaacag ctggagggat agtaggtaga ttagaaaatg
     2761 gtgcattgat atctaattcg gttgctactg gagaaatacg aaatggtcaa ggatattcta
     2821 gagtcggagg aatagtagga tctacgtggc aaaacggtcg agtaaataat gttgtgagta
     2881 acgtagatgt tggagatggt tatgttatca ccggtgatca atacgcagca gcagatgtga
     2941 aaaatgcaag tacatcagtt gataatagaa aagcagacag attcgctaca aaattatcaa
     3001 aagaccaaat agacgcgaaa gttgctgatt atggaatcac agtaactctt gatgatactg
     3061 ggcaagattt aaaacgtaat ctaagagaag ttgattatac aagactaaat aaagcagaag
     3121 ctgaaagaaa agtagcttat agcaacatag aaaaactgat gccattctac aataaagacc
     3181 tagtagttca ctatggtaac aaagtagcga caacagataa actttacact acagaattgt
     3241 tagatgttgt gccgatgaaa gatgatgaag tagtaacgga tattaataat aagaaaaatt
     3301 caataaataa agttatgtta catttcaaag ataatacagt agaataccta gatgtaacat
     3361 tcaaagaaaa cttcataaac agtcaagtaa tcgaatacaa tgttacagga aaagaatata
     3421 tattcacacc agaagcattt gtttcagact atacagcgat aacgaataat gtactaagcg
     3481 acttgcaaaa tgtaacactt aactcagaag ctactaaaaa agtactagga gcagcgaatg
     3541 atgcagcctt agataaccta tacttagata gacaatttga agaagttaaa gctaatatag
     3601 cagaacacct aagaaaagta ttagcgatgg ataaatcaat caatactaca ggagacggtg
     3661 tagttgaata cgtaagtgag aaaatcaaaa ataacaaaga agcatttatg ctaggtctta
     3721 cttatatgaa ccgttggtac gatattaatt atggtaaaat gaatacaaaa gatttatcta
     3781 cgtacaagtt tgactttaac ggaaataatg agacttcaac gttggatact attgtcgcat
     3841 taggaaatag tggactagat aacctgagag cttcaaatac tgtaggttta tatgcgaata
     3901 aacttgcatc ggtaaaagga gaagattcag tctttgactt cgtagaagcg tatagaaaac
     3961 tgttcttacc aaacaaaaca aataacgagt ggtttaaaga aaatacaaag gcatatatag
     4021 tcgaaatgaa gtctgatatt gcagaagtac gagaaaaaca agaatcacca acagccgata
     4081 gaaaatattc attaggagtt tacgatagaa tatcagcacc aagttggggg cataagagta
     4141 tgttattacc actactaact ttacctgaag aatctgtgta tatttcatcg aatatgtcta
     4201 cacttgcatt cggttcgtat gaaagatatc gtgatagtgt ggatggagtt attctttcag
     4261 gagatgcttt acgaacttat gtaagaaata gagttgatat agcagcgaaa aggcatagag
     4321 accattatga tatttggtac aatcttcttg acagtgcttc aaaagaaaaa cttttccgtt
     4381 ctgtgatagt ttatgatgga ttcaatgtaa aagatgagac aggaagaact tattgggcaa
     4441 ggttaacgga taaaaacatc ggctctatta aagaattctt cggacctgtt gggaaatggt
     4501 atgagtataa tagtagtgca ggagcgtatg cgaatggaag tttaacgcac tttgtgttag
     4561 atagattatt agatgcttat ggaacgtcgg tttatactca tgaaatggtt cataattctg
     4621 attctgcaat ctactttgaa ggaaatggta gacgtgaagg attgggagcg gagttatacg
     4681 cacttggttt actgcaatct gtagatagtg taaattctca tattttagct ttaaatacgt
     4741 tatataaagc agaaaaagat gatttgaata gattgcatac atataatccg gtggaacgtt
     4801 tcgattcgga tgaggcgctt caaagttata tgcatggatc atatgatgta atgtatacac
     4861 ttgatgcgat ggaagcaaaa gcgatattag ctcaaaataa tgatgttaag aaaaaatggt
     4921 ttagaaaaat agaaaattat tacgttcgtg atactagaca taataaagat acacatgcag
     4981 gaaataaagt ccgtccatta acagatgaag aagtagctaa cttaacatcg ttaaactcat
     5041 taatcgacaa cgacatcata aatagacgta gctatgatga taatagagaa tataaacgaa
     5101 atggctacta tactataagt atgttctctc ctgtatacgc agcgctaagc aattcgaaag
     5161 gtgctcctgg agatattatg tttagaaaaa tagcttatga attacttgcg gaaaaaggtt
     5221 atcacaaagg attcctacct tatgtttcta atcagtacgg agcagaagca tttgccagcg
     5281 gaagcaaaac attctcatca tggcatggaa gagatgttgc tttagtgaca gatgatttag
     5341 tatttaagaa agtattcaat ggtgagtact catcatgggc tgatttcaaa aaagcaatgt
     5401 ttaaacaacg tatagataaa caagataatc tgaaaccaat aacaattcaa tacgaattag
     5461 gtaatcctaa tagtacaaaa gaagtaacta taacaacggc tgcacaaatg caacaattaa
     5521 ttaatgaagc ggctgcgaaa gatattacta atatagatcg tgcaacgagt cataccccag
     5581 caagttgggt gcatttatta aaacaaaaaa tctataatgc atatcttcgc actacagatg
     5641 actttagaaa ttctatatat aaataagatt gtagagtttc attgttgagt agtgtttctt
     5701 gtaaggatga ggagtcagat gacaaatcga ctcctttttc ttatggatcg atgtagagat
     5761 ttgattgaat gcagattgca ggaatcatct tcaactcatc aacgaccaat ggtgacaagg
     5821 tggatttcaa tcccacagaa aatgttgatt tgagaaataa ctttgctagt ctagtaaaat
     5881 aaatacaaaa caatcctaga agattttttc tgggattgtt ttttgctgag tgggatgctt
     5941 caagttgtct ggcttgactt tcttgaggga agttatataa tagttgtaat aattaaagtt
     6001 acaataaaag aggaaatatt tatgacatat gaataccaga gccacattta tttagcagag
     6061 gcagttttaa atgtgaagga tttggtcagt caaacagttt tttatcagca gattattggt
     6121 ttagaaatcc tatctcaaac ggatacagag gtcgttctgg gacttggagg aaaagccttg
     6181 gtacacttga ttcaagcaca agagggtgga gaagtaaggg aacattatgg tctttaccat
     6241 ctggctattc ttttgccgac acgaaaggct ttggcggatg tcttgaagca cctgacggat
     6301 ttacagattc ctcttgttgg cggtgcagat cacggttaca gtgaggccct ttacttagag
     6361 gacttggagg gaaatggcat tgaactctat cgagataagc cagtttccac atgggatatt
     6421 cgagaagatg gacgtattat cggggtgact gaagtccttg cggctcagga tatctatgag
     6481 ttgggggaaa gagtagagcc ttttatccta gcagagggta cgagaatggg gcatattcat
     6541 ctttctgtca aggatagtcg aaagtccaga cagttttatc aaacggtgtt agggctcgag
     6601 gataaattca gtgtgcctag tgctagttgg atcgcagctg gggactacca tcatcattta
     6661 gcagtcaacg aatggggagg aaaaggtctg gatccgcgta aacaagtcct accaggttta
     6721 gcctactatg tcatcgaagt cgcacataaa gaagaactgt taacgattgc ccaacgagca
     6781 caagaagttg acgcaccaat caaatggatg acatcgatcc aattggaaat cacagactca
     6841 gatggcatcg tgacccgtat tcgtttagct agatagatgg tatgtgatga aggtagagca
     6901 tcaattgtag aaagtgctcc ttattctagt cagatacgtg gaaaatttga tatgatagta
     6961 gggaataagg agaagaataa tatgactagc gaataccaga aaatgatagc aggagagttt
     7021 taccgtccat cagacccaga actgagagcc ttagctcagg cttctcgcca aaaacaggcc
     7081 gcctttaaca aggaagagaa ccccttgaag ggagccgaaa tcatcaagac ttggtttgcc
     7141 tcaaccggga aaaatcttta catcaacact cgcttgatgg tggactacgg tgtcaacatc
     7201 catctagggg aaaattttta ttctaattgg aacttgacca tgctggatat ctgtcccatt
     7261 cgtatcgggg acaatgctat gattggtcct aattgtcagt ttttgacacc cctccatcca
     7321 ctagatccac aggaacgcaa ttcaggtatc gagtacggaa agcctatcac aatcggagat
     7381 aatttctgga ctggtggtgg cgtcattgtc cttcctggag tgacactggg aaataatgtc
     7441 gttgcaggag caggggcagt aattaccaaa tcttttggcg acaacgttgt cctagctggc
     7501 aatcctgcgc gcgtgattaa ggaaatacct gttaaataga agtaaaaagg aacagctggg
     7561 gttgtttctt ttttgtaggt ttcatcattt tttacccagt tcacatttac ctactctatc
     7621 tcttagcaag tctgtttcat taagcaagtt caaagcatct cgtaagtggg atgtttttct
     7681 cctcagttca tcagcttcct ccttgacact cggtcagatt ttgatacaat agtacaaaat
     7741 tagaggaggc aggctatgat tcagaaacat gcgattccta ttttagagtt tgatgacaat
     7801 cctcaggcgg ttatcatgcc caatcacgag gggctggact tgcagttgcc aaagaagtgt
     7861 gtttatgcat ttttaggtga ggagattgac cgctatgcga gggaagtagg ggcgaactgt
     7921 gttggcgaat ttgtttctgc caccaagacc tatccagttt atgtcgtgaa ctacaaggac
     7981 gaggagattt gtctggttca ggctcctgtc ggttcagctc cagcagccca gtttatggat
     8041 tggttgattg gctatggtgt ggagcagatt atctctactg ggacctgtgg tgtcctagct
     8101 gatatagagg aaaatgcctt tctagtccct gttcgcgctc tgcgagatga aggagccagt
     8161 taccactatg tggcaccttc tcgttatatg gaaatgcagc cagaggctat tgctgccatt
     8221 gagcgagttt tggatgatag agggattcct tatgaagaag tcatgacctg gtccacagat
     8281 ggtttttacc gagaaacggc tgaaaaggtg gcttatcgta aggaagaagg ctgtgctgtt
     8341 gtggagatgg agtgttctgc tcttgcggca gtagctcaat tgcgtggagt tctctggggt
     8401 gaattgttgt tcacagcaga ttctctagcg gacttggacc agtacgacag tcgtgactgg
     8461 ggctcggaag cttttaataa ggcactagaa ctgagtttag caagtgttca ccacctttag
     8521 ttgtactggc aaaggatttg ttttatcata aaatgtctag ctcatacttt tcaaaaatat
     8581 gtttaaacga ggtcaccttc ctcttgtcct aggcatgttg aggttgggaa aaatctttaa
     8641 aatcagaaaa acgtatcata tcaggtgatg aaaattttga tactatgcgt tttatgttgg
     8701 taagatttag agtgagatga aatgatactc ttcgaaaatc tcttcaaacc aggtcagctt
     8761 caccttgccg tatagatgtt actgacttcg tcagttctat ctgcaacctc aaaacagtgt
     8821 tttgagctga cttcgtcagt tctatctgca acctcaaaac agtgttttga gctgacttcg
     8881 tcagttctat ctgcaacctc aaaacagtgt tttgagctga cttcgtcagt tctatccaca
     8941 acctcaaaac agtgttttga gcaacctgtg actagctttc taagcgatgc cttggttctc
     9001 attgcctata atcaaaaaga gaaattttct cctgaaaagc atatagagta gctggcgtta
     9061 aaagctcctg tcttgctttt ttgacctata gtcacatcta tcaagtattg ttcttgccta
     9121 agctatcaat aaaaaggtgg cattttttag gcttggtgtt agtagatttt gccttatcct
     9181 atctaagtca tttcgaactt tttatggtac aatggaaaca tgttattcaa attatctaag
     9241 gaaaaaatag agctaggctt atctcgttta tcgccagccc gtcgtatttt tttgagtttt
     9301 gccttggtca ttttactagg ctctcttctt ttgagcttgc cctttgtcca agttgaaagc
     9361 tcacgagcga cttattttga tcatcttttc actgctgtct ctgcagtctg tgtgacaggt
     9421 ctctcaaccc ttccagtagc tcacacctat aatatctggg gccaaataat ctgtttgctc
     9481 ttgattcaga tcggtggtct agggctcatg acctttattg gggttttcta tatccagagc
     9541 aagcaaaagc ttagtcttcg tagccgtgca actattcagg atagttttag ttatggagaa
     9601 actcgatctt tgagaaagtt tgtctattct atttttctca cgaccttttt ggttgagagc
     9661 ttgggagcta ttttgcttag ttttcgcctt attcctcaac ttggctgggg acgtggtctt
     9721 tttagttcca tttttctagc gatctcagcc ttctgtaatg ccggttttga taatttaggg
     9781 agcaccagtt tatttgcttt tcagaccgat ttactggtca atctggtgat tgcaggcttg
     9841 attattacag gcggccttgg ttttatggtc tggtttgatt tggctggtca tgtaggaaga
     9901 aagaaaaaag gacgtctgca ctttcatacg aagcttgtac tattattgac tataggtttg
     9961 ttgttatttg gaacagcaac tactctcttt cttgagtgga acaatgctgg aacgattggc
    10021 aatctccctg ttgccgataa ggttttagtt agcttttttc aaacagtgac gatgcgaaca
    10081 gctggctttt ctacgataga ttatactcag gctcatcctg tgactctttt gatttatatc
    10141 ttacagatgt ttctaggtgg ggcacctgga ggaacagctg ggggactcaa gattacgaca
    10201 ttttttgtcc tcttggtctt tgcacgaagt gagcttctag gcttgcctca tgccaatgtt
    10261 gcgagacgaa cgatcgcgcc gcgaacggtt caaaaatcct ttagtgtctt tattatcttt
    10321 ttgatgagct tcttgatagg attgattctg ctagggataa cagccaaagg caatcctccc
    10381 tttatccacc tcgtatttga aaccatttca gctcttagta cagttggtgt aacggcaaat
    10441 ctgactcctg accttgggaa attggctctc agtgttatca tgccacttat gtttatggga
    10501 cgaattggtc ccttgacctt gtttgttagc ttggcagatt accatccaga aaagaaagat
    10561 atgattcact atatgaaagc agatattagt attggttaag aaaggaaaga gcatgtcaga
    10621 tcgtacgatt ggaattttgg gcttgggaat ttttgggagc agtgtcctag ctgccctagc
    10681 caagcaggat atgaatatta tcgctattga tgaccacgca gagcgcatca atcagtttga
    10741 gccagttttg gcgcgtggag tgattggtga catcacagat gaagaattat tgagatcagc
    10801 agggattgat acctgcgata ccgttgtagt cgcgacaggt gaaaatctgg agtcgagtgt
    10861 gcttgcggtt atgcactgta agagtttggg ggtaccgact gttattgcta aggtcaaaag
    10921 tcagaccgct aagaaagtgc tagaaaagat tggagctgac tcggttatct cgccagagta
    10981 tgaaatgggg cagtctctag cacagaccat tcttttccat aatagtgttg atgtctttca
    11041 gttggataaa aatgtgtcta tcgtggagat gaaaattcct cagtcttggg caggtcaaag
    11101 tctgagtaaa ttagacctcc gtggcaaata caatctgaat attttgggtt tccgagagca
    11161 ggaaaattcc ccattggatg ttgaatttgg accagatgac ctcttgaaag cagataccta
    11221 tattttggca gtcatcaaca accagtattt ggatacccta gtagcattga attcgtaaag
    11281 agggatgacc cctctttttt gatgcctaag atggcaaata gagacagaag ccccttgtct
    11341 tctagtaaaa gttcttcaaa ggctggactt tatggtaaaa tagaaagaag tgacaagaga
    11401 gagtaatact caatgaaaat caaagatcaa actaggaaac tagctacggg ctgctcaaaa
    11461 cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac ggcaaggcga
    11521 cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc ccctaaagga
    11581 gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag cctatcttca
    11641 ttactgtgtg gagtcgctag tgattggctg ggaccaggtc ggaaatttct ccaaaggcca
    11701 gtatatcatg atgcactcgc tgatttatcg gacagatttg ttgcgtgcta gccagttcta
    11761 actgcctgaa catacttttt atgtcgataa tctctttgtc tttacgcccc ttcagcaggt
    11821 caagaccatg tactatctgc ctgtcgattt ctatcgttat ttgattgggc gtgaggacca
    11881 gtctgtcaat gagcaagtga tgattaagtg cattgaccag caactcaagg tcaatcgact
    11941 cttgatagac caacttgatt tgtcccaagt gagtcatccc aaaatgcgag aatatctgct
    12001 gaatcatatt gaactcacga cggtgatttc cagtaccctg ctcaaccgat ctggaacagc
    12061 ggagcaactg gcaaaaaaac gccaattgtg gacctatatt cagcagaaaa atccagaagt
    12121 ctttcaggct attcgtaaga ccatgttgag ccgtttgacc aaacattctg tcttgccaga
    12181 tcgcaaactg tccaatgtcg tctatcaaat caccaaatct gtttatggat ttaattaata
    12241 taagtgtttt ataagaggga tttaagaaaa attttaactt tttcttagtc ctttttaatt
    12301 tcaggagatt atactagagt catcaaataa agaaagactc taaggagaat cctatgaaat
    12361 tcaatccaaa tcaaagatat actcgttggt ctattcgccg tctcagtgtc ggtgttgcct
    12421 cagttgttgt ggctagtggc ttctttgtcc tagttggtca gccaagttct gtacgtgccg
    12481 atgggctcaa tccaacccca ggtcaagtct tacctgaaga gacatcggga acgaaagagg
    12541 gtgacttatc agaaaaacca ggagacaccg ttctcactca agcgaaacct gagggcgtta
    12601 ctggaaatac gaattcactt ccgacaccta cagaaagaac tgaagtgagc gaggaaacaa
    12661 gcccttctag tctggataca ctttttgaaa aagatgaaga agctcaaaaa aatccagagc
    12721 taacagatgt cttaaaagaa actgtagata cagctgatgt ggatgggaca caagcaagtc
    12781 cagcagaaac tactcctgaa caagtaaaag gtggagtgaa agaaaataca aaagacagca
    12841 tcgatgttcc tgctgcttat cttgaaaaag ctgaagggaa aggtcctttc actgccggtg
    12901 taaaccaagt aattccttat gaactattcg ctggtgatgg tatgttaact cgtctattac
    12961 taaaagcttc ggataatgct ccttggtctg acaatggtac tgctaaaaat cctgctttac
    13021 ctcctcttga aggattaaca aaagggaaat acttctatga agtagactta aatggcaata
    13081 ctgttggtaa acaaggtcaa gctttaattg atcaacttcg cgctaatggt actcaaactt
    13141 ataaagctac tgttaaagtt tacggaaata aagacggtaa agctgacttg actaatctag
    13201 ttgctactaa aaatgtagac atcaacatca atggattagt tgctaaagaa actgtcgaaa
    13261 aagctgttaa aga
//
LOCUS       DAVMCN010000045        12858 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVMCN010000045 DAVMCN010000000
VERSION     DAVMCN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.046"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..550
                     /locus_tag="VYP85_001569"
                     /pseudo
     CDS             1..550
                     /locus_tag="VYP85_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(667..1014)
                     /locus_tag="VYP85_001570"
     CDS             complement(667..1014)
                     /locus_tag="VYP85_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1882055.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1125..2900)
                     /gene="spxB"
                     /locus_tag="VYP85_001571"
     CDS             complement(1125..2900)
                     /gene="spxB"
                     /locus_tag="VYP85_001571"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1882056.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3107..5350)
                     /locus_tag="VYP85_001572"
     CDS             complement(3107..5350)
                     /locus_tag="VYP85_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1882057.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTTIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFRLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5360..5731)
                     /locus_tag="VYP85_001573"
     CDS             complement(5360..5731)
                     /locus_tag="VYP85_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1882058.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5742..6137)
                     /locus_tag="VYP85_001574"
     CDS             complement(5742..6137)
                     /locus_tag="VYP85_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1882059.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     SRLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6321..6419
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6503..7294
                     /gene="thiD"
                     /locus_tag="VYP85_001575"
     CDS             6503..7294
                     /gene="thiD"
                     /locus_tag="VYP85_001575"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1882060.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDAYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7505..8137)
                     /locus_tag="VYP85_001576"
     CDS             complement(7505..8137)
                     /locus_tag="VYP85_001576"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1882061.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGAGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8130..8933)
                     /locus_tag="VYP85_001577"
     CDS             complement(8130..8933)
                     /locus_tag="VYP85_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1882062.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8933..9457)
                     /gene="thiW"
                     /locus_tag="VYP85_001578"
     CDS             complement(8933..9457)
                     /gene="thiW"
                     /locus_tag="VYP85_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1882063.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9462..10154)
                     /gene="tenA"
                     /locus_tag="VYP85_001579"
     CDS             complement(9462..10154)
                     /gene="tenA"
                     /locus_tag="VYP85_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1882064.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10165..10815)
                     /locus_tag="VYP85_001580"
     CDS             complement(10165..10815)
                     /locus_tag="VYP85_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1882065.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10817..12202)
                     /locus_tag="VYP85_001581"
     CDS             complement(10817..12202)
                     /locus_tag="VYP85_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882066.1"
                     /translation="MGLELRAIQSPIFPEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSPPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTEVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTF
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRDFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12203..12763)
                     /locus_tag="VYP85_001582"
     CDS             complement(12203..12763)
                     /locus_tag="VYP85_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1882067.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
BASE COUNT         3862 a         2838 c         2481 g         3677 t
ORIGIN      
        1 cgttttaaat atagtagacg ttttcgtaag gttcgcttga tgtaccaaga tgaggctggt
       61 ttcggtagaa tcagtaaact gggatcttgt tgggctccaa taggagtagg tccacatgtc
      121 catagtcact atatacgaga atttcgctat tgttatggag ctgttgatgc cccatacagg
      181 cgaatcattt ttcttaatag ctggtggatg taatactgag tggatgaacg cctttttaga
      241 agagctttca caagcttatc cagatgatta tcttttactc gttatggaca atgctatatg
      301 gcataaatca agtatcttaa agattccgac taatattggt tttgcattta ttcctccata
      361 cacaccagag atgaacccca ttgaacaagt gtggaaagag attcgtaaac gtggatttaa
      421 gaataaagcc tttcgaattt tggaagatgt catgaatcaa ctccaagatg tcatacaagg
      481 attggagaag gaggtgataa agtccatcgt taatcggaga tggactagaa tgctttttga
      541 aagcagatga gtataatatg caatttcttt atataaaaag accggattgc tccgatcttt
      601 caatagttca tattctcaat ttctatttta aaaatagcta aggttaacgt caaatgacta
      661 cgcgacctat ttcatacgat aaaaatcaag cactagacca gcaggtcctt gaactaataa
      721 ggactctgtt ccccaatcgg ttacagttgg tccgtgtaaa acctttatac caagctcgtt
      781 caaccgtttg tagttctggt ctacatcctc aacctcgata tgaataatga ttcctgactg
      841 aaagttttcc aaaggaacca aatgattttg tgacaacata aggcagtgac taccaatcgt
      901 aaactgagca aaaccatcat cagcataatc tgccttttta tccaaaatat gctccaagtc
      961 agcacagact tggggaacat ttgaaacgat aatatctaat tgatttaaat tcatttactc
     1021 tcctccataa aaagaccgga ttgctccgat cttttaaagt tctgctctat gaaaatcaaa
     1081 gaataaagtc tacaagtttc atatttgatt ttcggcgaga ggaattattt aattgcgcgt
     1141 gattgcaatc cttcttcttc caagaagaga cggaatggta cgagttcttc tgcttcgtat
     1201 ttttccttga aggctttgat agcttcttct gagtgaagtt ttggatccaa ttcaagtact
     1261 tctactggaa gtggacggtg ttgagtgatg cgagcatcga tgacaacagt tttaccttct
     1321 ttgttcaatt taacagcttc tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg
     1381 aatccaacag ctccttgagc ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca
     1441 ccaaacaagt gtttgtttgt atcttcgtat ttgttcttga tgaagccgta ctcagcattt
     1501 gagaagacaa ggttgataac tggaaggtcg tattgaacgt ttgtgataac gtctgggtag
     1561 cacatgttga atgctccatc acccatgatg ttccatactt ggcgatctgg attgtctttc
     1621 ttagcagcga taccaccagg aagggcaata cccattgtcg caaagagtgg agatgtacgc
     1681 cacatgttct taggtgtcat gtgaaggtga cgagtagatg tttgagtagt gttacctacg
     1741 tcgattgagt agatagcgtc ttgatcagca tgtttgttga ttgcattgta aacttgatac
     1801 aattgcaatt caccctcagt tttaccttcg agtttgttca tgtaatcacg ccagttttgg
     1861 ttattcttaa cgtttgcacg ccaccatgga gttgattcaa ctgggtttac tttgtcaagg
     1921 atagctttag ctgcttgacc agcatcacca aggattgaag cgtcaagggc atgacgttta
     1981 ccaagtttgt aagggtcgat atcaacttgg atgaattttt cagtgttctt gaatgcttcg
     2041 taaacttcag caaatgggaa gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc
     2101 acttcgttgg ctggtttcca accaacacga taagcagaac ctgtcaaacc ttcatagttc
     2161 cattcgaaag cttcaaagtt tttaccagtt gtgatgattg gtgctttgat tttacgtgac
     2221 aattcagtaa tcacttcacc agctttaaca ccaccaaatc cagcatagat aactgggcgt
     2281 tcagcattgt tcaagatttc aacagctttg tcgatttcaa cttcgttcaa agcaggagcg
     2341 atgaatgagc gttcgtatga acctgaaccg tagtatgagt tttcgtcgat ttcttggaaa
     2401 ccgaagttta ctggaatttc aacaacagct ggaccttttt tagaaattgc agcacggcag
     2461 gcttcgtcaa ttacttttgg caattgctca gcgtaagcta cacgtttgtt gtaaacagcg
     2521 ataccgttgt acattgggtt ttggttaagc tcttggaaag catccatgtt caattcgtta
     2581 actggacgtg atccaaggat cgctaggaat ggagtgttat ccatagctgc atcgtaaaca
     2641 ccgttaatca agtgagtcgc acctggacca cctgaaccaa ctgcaacccc gattgagccg
     2701 ccgaatttag cttgcataac cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag
     2761 aagcggatat ctttgtcttc agccaaagcg tccatcaatg agctgagtgt tcctgatggg
     2821 ataccgtaga ttgtatctac gccccatgtt ttcaatacgt taagcattgc tgcagatgca
     2881 gtaattttcc cttgagtcat aatgataact ctccttcaat ttttttagat ttggagaata
     2941 cgattacata gaattggaaa cgttctccaa atttttacta ttccactgta tcatatttat
     3001 gctgactttt ctaaaaatct gctcaaaact ctctattctc tattctaata cagttttgaa
     3061 agttctgtca tttctgtttt ataacaaaga aatctagtca ttacttttag tctattttac
     3121 taaaatttaa cagaagggaa ctggtcagaa cagatacaga actaaaggcc atggctagac
     3181 ctgccaattc tgggttgaga gccagtccaa cacctgaaaa gactcctgct gcaatcggaa
     3241 ttccgacaac attgtagata aaagcccaga aaagattgag tagaattcga tgaaaggttt
     3301 tcttactcat atcaaaggca cgaaccactc ctaaaagatt attggttgtc aacaccaaat
     3361 ctgctgactc gatggcgata tctgttccag ctcccatagc aatccccaca tctgctacac
     3421 taagggcagg agcgtcattg ataccgtccc caacaaaggc tactttccct gactgttgca
     3481 gtttatggat ttcatgggct ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc
     3541 cgatttgatc tgcaatagca cgcgccacac cagcattgtc tcctgtcagc atgactgttc
     3601 ggagaccacg tttttttagc tgactgatgg ctagcttagc attttcctta ggaatatctt
     3661 gcaaagcaag caagcctttg atttcattgt caacagctaa gaacacaact gtcttagctt
     3721 ctttttctag ttcttctagt ttatcttgat aagtattaga aatatccatg ccatccagca
     3781 ttttagcatt tccaagtaaa acttgttttc cattgattcg ccctgaaaca cctttcccgt
     3841 gcaaggtctg aaaattttca acagtttgaa actcaagtcc agcttcactc gctcgcttaa
     3901 cgatagcctc agccagtggg tgttgagaag catcttccaa ggaggctgcc aacctaaaca
     3961 cttctacttc gtcgccgatg acatctgtta ccacaggttt cccttccgtc aaagtcccgg
     4021 tcttatcaaa gacaagggtt tgaactttct ggatttcctg taagacagtt ccatttttga
     4081 ggagaacccc catcttggca ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa
     4141 gtcccaaggc acaaggacag gcgataatca aaaccgccac tccgtagaga agagaggaca
     4201 caaagctagc tccaagcaca accacactat ccctgagcaa gacgaaccaa acccaaaagg
     4261 tcatgattcc taaaatgaca actactggga caaaaatccc tgaaatctta tccgtcaagt
     4321 cttgaatcgg cgcacgactt gtctgagctt tcttcacaaa atccacaatc tgagccaaaa
     4381 cagtctctga gccaactttt tctgctctaa agacaagcgt tccactatga ttgatggttg
     4441 agccaatgac agtatctcca actgtcttgt ccacaggcag actctcacct gtcaccatgg
     4501 attcgtcaat actagagaca ccttctacta cgacaccatc aacagcaatc ttttcaccgg
     4561 gacgcactcg aatcaggtcg cctaccttga cttgttccaa aggaacttgg acataactat
     4621 catcactcaa gacttctgcg gttttagctt gcaagtccag taatttctcc acagcttggg
     4681 acgtattttt tctcattttt tcctcaaaaa ctgctcccaa aagaacgaaa aagaggataa
     4741 atccagcact ttcgaagtaa acagggagac cagcaaagag agcaactagg ctatagaaat
     4801 aagccactag agttcccagc gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac
     4861 tggcccaagc actctggata tatggcttac ctgcaactaa cataatagtc gttgttgcta
     4921 gaaaggttcc ccaatgcatg acttgatgac taatgctacc tgtcaacatc ccaatcatga
     4981 gaatcacaag aggcacagta aagatactag taatccaaaa acgttgcagg agagatagag
     5041 attttcgagt cttctcaacg actgtatagc ttcccttttg catcttcatg ccacaagaaa
     5101 attcatgtcg ccctaattct tgaggtgtaa aacgaatgac tttctcctca tctacgccga
     5161 ttggttccaa gataccttct tcttcaaaca gaatttcctt ataacagttt gaaggagtag
     5221 cacgatgaaa ggtaatctca gctggaattc ccttttgaag ctggatatgg gctggatgat
     5281 agcctttttc agctcggata cggatttttt gaatgccatt ttctaagctt gctttcacaa
     5341 tttctgtcat agtctccacc tactctacaa tcatcttgcc gtgcatcatg ttcataccac
     5401 aagcaaagcc aaactctcca gcctgctcag gcgtgatttc cactacatac tcttccccca
     5461 ttggcaggtt cgtatgtaca ccaaaatctg gaaaaacaat ttgatccaga catggtgaag
     5521 gatccttgcg gtcaaagaca atgcgtgctg gcactgattt cttgaggaca atcaactcag
     5581 gagtatagcc tcccatgact tccactcgaa tctcttggta tccatttttt tgctgggctt
     5641 tttgtccaga tttttcaggc tttttgaaaa accaaaacaa gataaacgcg ataagggcaa
     5701 tacaaataat ggttacaata ctatttaaca tgacgtctcc tttacataca attacatctt
     5761 acttctgtta cagcacttga tttcttctct gaaatcacag cttccaagtc ttccaagtca
     5821 gtctgagtaa attcacattc tacaatcaag tcagccaaca aattcctaat cctacgggaa
     5881 caaaccttgt ctttgatatc ttggacaagt aaatcccgac tttggtctag agttaaaagg
     5941 gctgaataaa caaaggactt gccttctttt ttccgagtca aacactcttt ctcaaccagc
     6001 cgagacaaaa gtgtctgaac cgttgacttg gaccaatcaa accgctctgc caaaacccta
     6061 atcaaatctg tactggtctg ctccccctgc atccaaataa tcttcatgac ctgccattct
     6121 gcatctgaaa tctgcattac catacctcca aaatctacat ttgtcaatta cactcatcag
     6181 tatactctca aaatctacat ttgtcaatta tagaaataat attttcttcg aaaaatagaa
     6241 ttttaatcat ttgaaaaacg atttgcagtc aaatattact atataaacaa taaaaatatg
     6301 ctatactaaa gaaaaaagaa aacaaccact aggggtgcgt aaagctgaga ttaacgactg
     6361 ttagatccct ctgactcaat ctaggtaatg ctagctgatg gaagtggaaa tgataatggg
     6421 gactagcagt cttctattgc ctttctaaaa cagactagct tgttcttaag aatacaaact
     6481 tcagttggtt gggaggtttt agatgactta tttacccgtt gctttgacca ttgcagggac
     6541 tgaccctagt ggtggtgctg gcattatggc agatttaaag tcattccaag cgagagatgc
     6601 ctatggaatg gctgttgtaa ccagtcttgt cgctcaaaat accagaggtg ttcagctaat
     6661 cgaacacgtt tctcctcaaa tgttgaaagc ccaattggac agtgtctttt ctgatattcc
     6721 acctcaggct gtaaaaactg gaatgttggc tactactgaa atcatggaaa tcatccaacc
     6781 ctatcttaaa aaactggatt gtccctatgt ccttgatcct gttatggttg ctacaagtgg
     6841 agatgccttg attgactcaa gtgctagaga ctatctcaaa acaaacttac tacctctagc
     6901 aactattatt acgccaaatc ttcctgaagc agaagagatt gttggttttt caatccatga
     6961 ccccgaagac atgcagcgtg ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt
     7021 ggttatcaaa ggcggacatc tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga
     7081 acaatttgtc tgggaaagcc cacgaattca aacctgtcac acccatggta ctggatgtac
     7141 ctttgctgca gtgattactg ctgaactagc caagggcaag agtctttacc aggcagttga
     7201 taaggccaag gcctttatca caaaagctat tcaagatgcc cctcaactcg gtcatggttc
     7261 tggtccagtc aaccatacaa cttttaaaga ttaagaaaaa aaaactctct agttcccact
     7321 ttaagggaat tagagagttt ttatactctt cgaaaatctc ttcaaactac gtcagcttcc
     7381 atctgcaact tcaaaacact gttttgagct gacttcgtca gtcttatcta aaacctcaag
     7441 gcagtacttt gagcaacctg cgactagctt tctagtttac tctttgattt tcattgagta
     7501 ttaattagga aagaatgtca tgcaactttg ttaaaaaggc ttgcgttttt gcctcaatat
     7561 cttctgcttg catcaaatca cgtacaacag ctacaccagc tatgccagcg cccataagct
     7621 gatcaatatt ctccgaagtc aagccaccaa tagcaactat tggaatggca accgtttggc
     7681 aaattgtttt caaggttgaa atcagggtga tgggtgcatt ttccttggtg gttgtcggaa
     7741 aaatggctcc tgtccccaag taatctgcac ctgatttctc cgcttccaga gctcttttaa
     7801 ccgttttagc ggtgacaccg aggatttttt caggacccaa gacttgtcgg gcaaccgaaa
     7861 ctgggagttc gtcatctcca atatgcagac cagcagcatc aaccgcaaga caaacatcca
     7921 accgatcatc gattatcaag ggtacctgat aagcatctgt tatttccttg acttgttttg
     7981 ccagttgata atattgattg gttgtgagat ttttttctcg caattggact atggtaaccc
     8041 ctgaacggca ggccgtctca acttttgcaa gaaagctttc cacggaatct tgatagcgat
     8101 tggttaccag atatagtcta agtgcttctc tattcataaa cctctccttt gatggtatct
     8161 agccaatttt catctcttct taggagcgaa agctgattga gtacttggta acgaaattct
     8221 tccaatccca ttccttgaac aactattttc tcagcagcga tattgagata agagactgct
     8281 aagcaagaag cttcaaaacc agtctttcct tggctgagaa aaacggctgt taaggctcca
     8341 accaaatctc ctgtccctgt tatccagtct aattctgcac agccatttcc cagtacagcg
     8401 acctgatttt tcgaaacgac gaggtccttg ggacctgtga ctaagaaaga cataccatga
     8461 taggtctgac accagtcttt caagacttga agcaaatcct ccgtttcttg atctttagca
     8521 ctcgcatcga ccccaacgcc gtggtgcttt aatccaacaa gacttcgaat ttctgacatg
     8581 tttcctttaa ggaccgtagg tctatagtct aaaaggtctc tgactaagct cttacgaatg
     8641 gatgaagtcg ttacgccaac cgcatctact accatcggga gagaagattg gtttgcatac
     8701 aaagctgcca tgcggattgc tttttccttc tcagctgaca aatgccccaa attgatgaag
     8761 agagcctgac tttgcttagt aaaatcaaga acttcacggg gatcatctgc catgacaggt
     8821 ttgcatccca gagccaaaat cccatttgcc agcatctcac aagaaatctc attggtcata
     8881 cagtgaatga gggaactaga gcctatagga aaaggatttg tcaatgcctg catcattcta
     8941 tcctttcagc aaagaaatat ccttgcactt ttttaaagaa ttcctgcttg attaaaaatc
     9001 taaatgcaat aaaggaaatc gctgtaccaa tcaaggttgc tccgaaaaat cgaggagtgt
     9061 agataaacca actaagctta gcagccgatc ctgtaaagag caccataaca ggataggaaa
     9121 caatagaacc aataatacct gttcccacaa tttctcccaa ggcagaaaag taaaattttc
     9181 gaccgtactt ataaaagaga cctgctagaa gggctccaaa agtcgctcct gtgagagcta
     9241 aaggcggaat cccttgagtc gtcatacgga taaaggctgt cactgtagcc atagccaagg
     9301 cataaacagg tcccatcatg attcccgcta gaatattgac tacactggac atcggtgcca
     9361 ttccctcaat ccgaaagata ggtgtaagga ctacatcaag ggcaatcatc atagataaaa
     9421 tggtcaattt gtgaacttgt agttggtgct ttctcatgtt tctattcttc tcctttttct
     9481 aaagactgta aatcgctctt ccatgtctgg tgttggtaag ccatctccca aaacttggct
     9541 tccatatgaa cactgatgtg gaaggcatct agcatttttt gcttatctgt ctcatcactt
     9601 tctcgataaa gctgattgac cagtgctccc tcctctctga tctgttgctc taactcatcc
     9661 gtaatataag tttcaatcca ttgttgatag agaggatttg gtgatggttt aagattaagt
     9721 gatttgccta tatcatggta taaccaagga caaggaagca agcttgcaaa agctatggct
     9781 aagttcggtt ctgcaaattg cctataaata tgagaaatgt aatgataaca ggttggagcg
     9841 attggatgtt gctccatttc ctggtcgttg atttccaatt ccttgaaaaa ttgttggcga
     9901 ataaataact caccctccac taaaccctga gcattttgtt tcaagagtct tttcatctct
     9961 tggtttgaag tcttatcagc caaaagatga tagatttctg agaaagcctt cagatagtag
    10021 gcatcctgaa tcaggtaata gcggaaaatg gcaggttcta aattcccctc ttgtaattgt
    10081 aaaataaagg gatgatgaaa ggaagcctgc caagctttct tggataattc catcgcaata
    10141 tctgtaaatt ccataataac tcctttataa aaatagactg gtttgaagca ataaaaagaa
    10201 aagcaggtag attaattttg tttttttagg aatataaaaa gtccgatagc tattcttcaa
    10261 ctgtgcatgt tcgtcatatc cgtgagcaga tagagctctc aggtaaagat ggcgccacct
    10321 aaagactgtc atcagaacct tactgtaaat caagggcgac caaaaatgta gtttttgacc
    10381 acgtaatagg caagcttctt tgagggactt gatttcttgc tgaatgagag gaaaagaatt
    10441 gaataccaca atcaaggcat aggaccaaga gcgtgatagc cccttttgag ccaagtacaa
    10501 gagaagctct tttagtgaaa tagaggaaac aaagacaagg ccgatacaaa ctgtcacaaa
    10561 ggccctcgtt ccaagcatga ctgcctgtga agcatctccg tgtaactgaa ctgcccagta
    10621 gttggcaaaa gatggtaaaa tggcaagtat gatcatccaa gctaacattt taaatcgacg
    10681 gtaatagagc ataaagagaa tacaaaatgc gactaccgaa agattcagag caatcgaagg
    10741 aatgaaagat gtttccaagg ataaaatcag caagaagaga ctgataatcg gtgtctgggt
    10801 tgctactttg accatactat ctcacctccc cttgggtatt gctactctga gatgtaagtg
    10861 gtttggtaat ggtcacttct ttcacatgcc gaagaccctg actagtcatc tcaatccaat
    10921 aatcaaccac agaaatcaaa gggtctaaac gatgactaat gagcagaaaa cttcttcctt
    10981 gattcctctc ctccacaatc cacttgcaaa aataatggca ggctctatca tccaaacctg
    11041 caaaaggttc atctagcaag atcacggaag ccttactggt caagatggtc aagagctgaa
    11101 gaattttttg ctgaccacca cttaattgat agggactctt atcgactgcc tgctccaaat
    11161 caaaatctcg taaagcttga aaaatccgct gatttctttc agaatcaggt ccatctaatt
    11221 gaagctcctc tcgcagactg actcgaataa actgcttctc agcttcctga acaacaccag
    11281 tcagatcacg atacaaactc tttttctttt tcagaaccga acccttccaa gtaatgctcc
    11341 ccttatactt ttgaaattga agaatagagc gaaagaaggt tgatttcccg acaccattgt
    11401 cacccaggat acaggaaatc ccttgataga atgtgaaatc agcaattgaa aagagggagc
    11461 gatttccaaa ctcacaagtc gttctatcca tatggaatag ttccgggcta gaagcaactt
    11521 cctttgaagc aacctctgtc atctcatagg aagggatttg aaacacttcc cttagttttc
    11581 cgtctcttag ctcaaccata tggtcgatat aggctttata gtcagataaa tcatggtcgc
    11641 acaaaataac tgtcttccca tcaagagcca actcttttag aatctccaat atctcgattc
    11701 tgctcttgcg gtcaatggaa gcgaagggct catccaagag atatacccta ggattcatgg
    11761 caaagaggac agccagcgct gctttttgct tttccccacc tgataggtga tgaatgggac
    11821 ggtgtaagat tgcctcgcaa cgacattgct ggacaacctc tgctatttta gaatcaattt
    11881 cctgaaggtg atagccgata ttctccaagg tgaaaatcag ctcctcaaac aagttctcca
    11941 tggtaaattg atgattggga ttttgaaaga gaatgccaac cttctggaca cgtgcgatga
    12001 tagaaagctg actgacctcg ctcccatcta tcaggacttg accactatag ggaggagaac
    12061 tgacttgggc aatgacttga aaaaggctgg attttcctga accactgctc ccaactaaca
    12121 aggtaaaggc ttgcgcatga aaagtaaaat caaacggctc agggaagatt ggagactgaa
    12181 tcgctcgtag ttccagaccc atctatgctt ttcctccagt tgcaaactga tgatagagtt
    12241 tgacaatggc acgaaccaag atggtacaga agaaataaac agaaataaaa cgtaccacaa
    12301 gtaaggaaag gacaaacgga agggaaaagg cgtagtaacc taacttaatg tattcataga
    12361 caaagctaac aagcgtaatc ccaatactat tagcagttag agagagccaa ctttcatagc
    12421 gattcttagt tacgataaaa ccaaattcac ttcccaaacc ttgaaccaag ccagacaaaa
    12481 gagctcctag accaaattgg ctaccataaa ggacttcagc aagcgcagct agcacttctc
    12541 caatcgttgc acttccgact ctcggaacaa agatggcagc aatgggcgca gccatacacc
    12601 agagaccgaa gaggatttca ttggcaaagg cctgcaaacc aagaggtgtt aagagtagac
    12661 tgagaatatt atacacatat cctgaaccaa cgaaaacccc accaaaaaag atagacaaga
    12721 aagcaagcaa gataacatct tttaactgcc attttttcaa cataaaaaac tcctttttta
    12781 aaagaaaagt ggggcactca agaagaccga cctaaatact ttgtatagca gattgatttt
    12841 agaacagtac acaggaat
//
LOCUS       DAVMCN010000046        12852 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVMCN010000046 DAVMCN010000000
VERSION     DAVMCN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.047"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..1067
                     /gene="dnaN"
                     /locus_tag="VYP85_001583"
     CDS             <1..1067
                     /gene="dnaN"
                     /locus_tag="VYP85_001583"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1882068.1"
                     /translation="KNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLL
                     ITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRI
                     QEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHR
                     LSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYT
                     RLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVS
                     AHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFT
                     LVPADTDEDFMQLITPVRTN"
     gene            1132..1326
                     /locus_tag="VYP85_001584"
     CDS             1132..1326
                     /locus_tag="VYP85_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1882069.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1410..2525
                     /gene="ychF"
                     /locus_tag="VYP85_001585"
     CDS             1410..2525
                     /gene="ychF"
                     /locus_tag="VYP85_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1882070.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRASYHLLGLGTYFTAGEKEVRAWTFKRGMKATQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2596..3165
                     /locus_tag="VYP85_001586"
     CDS             2596..3165
                     /locus_tag="VYP85_001586"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1882071.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3166..6675
                     /gene="mfd"
                     /locus_tag="VYP85_001587"
     CDS             3166..6675
                     /gene="mfd"
                     /locus_tag="VYP85_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1882072.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKVPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASHPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSCLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIVENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6733..6999
                     /locus_tag="VYP85_001588"
     CDS             6733..6999
                     /locus_tag="VYP85_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1882073.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            6992..7360
                     /locus_tag="VYP85_001589"
     CDS             6992..7360
                     /locus_tag="VYP85_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1882074.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7480..8748
                     /locus_tag="VYP85_001590"
     CDS             7480..8748
                     /locus_tag="VYP85_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1882075.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8745..10022
                     /gene="tilS"
                     /locus_tag="VYP85_001591"
     CDS             8745..10022
                     /gene="tilS"
                     /locus_tag="VYP85_001591"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1882076.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFKKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRNAILGISNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10026..10568
                     /gene="hpt"
                     /locus_tag="VYP85_001592"
     CDS             10026..10568
                     /gene="hpt"
                     /locus_tag="VYP85_001592"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1882077.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10584..12542
                     /gene="ftsH"
                     /locus_tag="VYP85_001593"
     CDS             10584..12542
                     /gene="ftsH"
                     /locus_tag="VYP85_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1882078.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            12664..>12852
                     /locus_tag="VYP85_001594"
     CDS             12664..>12852
                     /locus_tag="VYP85_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1882079.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKF"
BASE COUNT         4420 a         1923 c         2639 g         3870 t
ORIGIN      
        1 ctaaaaatgc cattcctatt ttatcaacag taaaaattga cgtgaccaat gaaggtatta
       61 ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa aaaaatgaag
      121 atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct ttctttatca
      181 atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa caaaatcaaa
      241 ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc gaacaatatc
      301 cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa ttactcaaga
      361 aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg attttaacag
      421 gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca gactctcatc
      481 gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat gtcgtaattc
      541 ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa actgtagaga
      601 ttttctttgc caataaccaa atcctcttta gaagcgaaaa tattagcttc tatactcgtc
      661 tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt aacactacta
      721 ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt ttatcaagtg
      781 cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc gcccatgttc
      841 actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt actggtgaag
      901 atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct ttaaatagcg
      961 aaaaggtgac cattagcttt atctcagctg ttcgtccatt tactcttgtg ccagcagata
     1021 ctgacgaaga cttcatgcag ctaattacac cagttcgtac aaattaagtg aaagaggttg
     1081 agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag tatgtatcaa
     1141 gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc aactggtaaa
     1201 aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa atgcagtaat
     1261 tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa taaaattatt
     1321 gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta taatattagg
     1381 gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc gttggtttgc
     1441 caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca gaggcagcaa
     1501 actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca gatgaacgcc
     1561 tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca tttgaattta
     1621 cggatattgc agggattgta aaaggagctt caaaaggaga agggctaggg aataaattct
     1681 tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt gatgatgaaa
     1741 atgtgatgcg cgagcaagga cgtgaagacg cctttgtaga tccacttgca gatattgata
     1801 caattaatct ggaattaatt cttgctgact tagaatcagt gaacaaacga tatgcgcgtg
     1861 tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc aatgttcttc
     1921 aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa tttacagatg
     1981 aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt ctttatgtag
     2041 ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc aaacaaattc
     2101 gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt gctgaggaag
     2161 aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt ggtttgacag
     2221 aatcaggtgt agataagttg acgcgtgcat cttaccactt gcttggattg ggaacttact
     2281 tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg aaggctactc
     2341 aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca gtaaccatgt
     2401 catatgaaga tctagtgaaa tacggatctg aaaaggccgt aaaagaagct ggacgcttgc
     2461 gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc cgctttaatg
     2521 tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc ttttggcttt
     2581 tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg ggataaatat
     2641 tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa gaaacagaat
     2701 gtcactttta cacacgataa gatatttcaa gctgacctag catccttttt cctaaatgga
     2761 gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa agcagttcat
     2821 gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta cgatgatctt
     2881 gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg tcataatggt
     2941 atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa gattggaatt
     3001 ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt tgacagggat
     3061 gattatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa ctactattta
     3121 caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt gaccttatta
     3181 gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac agataagaaa
     3241 agacaactaa tacttggttt atcaacatct actaaggcgc ttgcaattgc aagcagttta
     3301 gaaaaagaag ataggattgt gttattgacg tcaacttatg gagaagcaga aggacttgtt
     3361 agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt agatgatgct
     3421 cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt tgaagccttg
     3481 cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc agcaagtcga
     3541 ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc agttggtgaa
     3601 gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg aaaagttact
     3661 caagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat ttttgaaata
     3721 tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg tatcaggtca
     3781 tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat ctttccagct
     3841 agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt agaaaaacaa
     3901 atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct ttcaagtttt
     3961 catcaaaagc aaagtcatgc agattctcgg aagtttttat ctttgtgcta tgataagaca
     4021 tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga ttatcaaaaa
     4081 ttgatgaatc agtatgaagt atttgaaaga gaattagcgc agtactttac agaagaatta
     4141 cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca aatctataaa
     4201 aaacaaagtc cagtgacctt tttctctaat cttcaaaagg gtttaggaaa tctcaaattt
     4261 gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca gttttctttt
     4321 ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct gcagtctagc
     4381 aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat taaattggat
     4441 tctagagata agacaagtat ctgtaaagaa tctgtaaact taatagaggg taatctcaga
     4501 catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga gatttttcaa
     4561 aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag attaaaagat
     4621 tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat tggtcaatat
     4681 ctaggaattg aaaccattga aatcaaggga attcatcgcg attatgtcag tgtccaatac
     4741 caaaatggtg atcaaatttc tattcccgtg gaacagattc atctactgtc caaatatatt
     4801 tcaagtgatg gtaaagttcc aaaactcaat aaattaaatg atggtcattt taaaaaggcc
     4861 aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa actctactct
     4921 gaacgtagtc agttgaaggg ttttgctttc tcagctgatg atgatgatca agatgccttt
     4981 gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga ggaaatcaag
     5041 agggatatgc aggcttctca cccaatggat cgacttttag ttggggatgt tggttttgga
     5101 aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa acaggttgtc
     5161 attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa ggaacgattc
     5221 caaaattttg cagttaatgt tgatgtgttg agtcgcttta gaagtaaaaa agagcagact
     5281 gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac acatcgtgtt
     5341 ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga ggaacagcga
     5401 tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga tgtcctaacc
     5461 ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat cagagatttg
     5521 tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt tttggaaaag
     5581 aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg tcaagtttac
     5641 tatctttaca acaaagttga cacaattgtt cagaaggttt cagaattaca ggagttgatt
     5701 ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt ggaaaatact
     5761 ctattagact ttattgaggg acaatacgat atcttggtga cgactactat tattgagaca
     5821 ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca tatgggcttg
     5881 tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc ttatgcttat
     5941 ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt agaagcgatt
     6001 aaaggattta cagaattggg ctctggcttt aagattgcaa tgcgagatct ttcgattcgt
     6061 ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt tggttttgaa
     6121 ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc taacgctaac
     6181 acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct tcctgatact
     6241 tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca aattgacaac
     6301 cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga atacccagat
     6361 gtagtagcct atctgttaga gattggtttg gtcaaatcat gcttggacaa ggtctttgtt
     6421 caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt cactcaacga
     6481 ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa agcaggcatc
     6541 gttgagaata agggattaat ggagcttgta tttgatgtcc aaaataagaa agattatgaa
     6601 attttagaag gtttgctgat ttttggagaa agtttattag agataaaaga gtctaaggaa
     6661 gaaaattcca tttgatattt ttcttctata aaatagataa aaatggtaca ataataaatt
     6721 gaggtaataa ggatgagatt agataaatat ttaaaagtat cgcgaattat caagcgtcgt
     6781 acagtcgcaa aggaagtagc agataaaggt agaatcaagg ttaatggaat cttggccaaa
     6841 agttcaacgg acttgaaagt taatgaccaa gttgaaattc gctttggcaa taagttgctg
     6901 cttgtaaaag tactagagat gaaagatagt acaaaaaaag aagatgcagc aggcatgtat
     6961 gaaattatca gtgaaacacg ggtagaagaa aatgtctaaa aatattgtac aattgaataa
     7021 ttcttttatt caaaatgaat accaacgtcg tcgctacctg atgaaagaac gacaaaaacg
     7081 gaatcgtttt atgggggggg tattgatttt gattatgcta ttatttatct tgccaacttt
     7141 taatttagcg cagagttatc agcaattact ccaaagacgt cagcaattag cagacttgca
     7201 aactcagtat caaactttga gtgatgaaaa ggataaggaa acagcatttg ctaccaagtt
     7261 gaaagatgaa gattatgctg ctaaatatac acgagcgaag tactattatt ctaagtcgag
     7321 ggaaaaagtt tatacgattc ctgacttgct tcaaaggtga taaaatggaa aatttattag
     7381 acgtaataga gcaatttttg agtttgtcag atgaaaagct ggaagaattg gctgataaaa
     7441 atcaattatt gcgtttacaa gaagaaaagg aaaggaagaa tgcgtaaatt cttaattatt
     7501 ttgttgctac caagtttttt gaccatttca aaagtcgtta gcacagaaaa agaagtcgtc
     7561 tatacttcga aagaaattta ttacctttca caatctgact ttggtattta ttttagagaa
     7621 aaattaagtt ctcccatggt ttatggagag gttcctgttt atgcgaatga agatttagta
     7681 gtggaatctg ggaaattgac tcccaaaata agttttcaaa taaccgagtg gcgcttaaat
     7741 aaacaaggaa ttccagtatt taagctatca aatcatcaat ttatagctgc ggacaaacga
     7801 tttttatatg atcaatcaga ggtaactcca acaataaaaa aagtatggtt agaatctgac
     7861 tttaaactgt acaatagtcc ttatgattta aaagaagtga aatcatcctt atcagcttat
     7921 tcgcaagtat caatcgacaa gaccatgttt gtagaaggaa gagaatttct acatattgat
     7981 caggctggat gggtagctaa agaatcaact tctgaagaag ataatcggat gagtaaagtt
     8041 caagaaatgt tatctgaaaa atatcagaaa gattctttct ctatttatgt taagcaactg
     8101 actactggaa aagaagctgg tatcaatcaa gatgaaaaga tgtatgcagc cagcgttttg
     8161 aaactctcct atctctatta tacgcaagaa aaaataaatg agggtcttta tcagttagat
     8221 acgactgtaa aatacgtatc tgcagtcaat gattttccag gttcttataa accagaggga
     8281 agtggtagtc ttcctaaaaa agaagataat aaagaatatt ctttaaagga tttaattacg
     8341 aaagtatcaa aagaatctga taatgtagct cataatctat tgggatatta catttcaaac
     8401 caatctgatg ccacattcaa atccaagatg tctgccatta tgggagatga ttgggatcca
     8461 aaagaaaaat tgatttcttc taagatggcc gggaagttta tggaagctat ttataatcaa
     8521 aatggatttg tgctagagtc tttgactaaa acagattttg atagtcagcg aattgccaaa
     8581 ggtgtttctg ttaaagtagc tcataaaatt ggagatgcgg atgaatttaa gcatgatacg
     8641 ggtgttgtct atgcagattc tccatttatt ctttctattt tcactaagaa ttctgattat
     8701 gatacgattt ctaagatagc caaggatgtt tatgaggttc taaaatgagg gaaccagatt
     8761 ttttaaatca ttttctcaag aagggatatt tcaaaaagca tgctaaggcg gttctagctc
     8821 tttctggtgg attagattcc atgtttctat ttaaggtatt gtctacttat caaaaagagt
     8881 tagagattga attgattcta gctcatgtga atcataagca gagaattgaa tcagattggg
     8941 aagaaaagga attaaggaag ttggctgctg aagcagagct tcctatttat atcagcaatt
     9001 tttcaggaga attttcagaa gcgcgtgcac gaaattttcg ttatgatttt tttcaagagg
     9061 tcatgaaaaa gacaggtgcg acagctttag tcactgccca ccatgctgat gatcaggtgg
     9121 aaacgatttt gatgcgcttg attcgaggaa ctcgcttgcg ctatctatca ggaattaagg
     9181 agaagcaagt agtcggagag atagaaatca ttcgtccctt cttgcatttt aagaaaaaag
     9241 actttccatc aatttttcac tttgaagata catcaaatca ggagaatcat tattttcgaa
     9301 atcgtattcg aaattcttac ttaccagaat tggaaaaaga aaatcctcga tttaggaatg
     9361 caatcttagg cattagcaat gaaattttag attatgattt ggcaatagct gaattatcta
     9421 acaatattaa tgtggaagat ttacagcagt tattttctta ttctgagtct acacaaagag
     9481 ttttacttca aacttatctg aatcgttttc cagatttgaa tcttacaaaa gctcagtttg
     9541 ctgaagttca gcagatttta aaatctaaaa gccagtatcg tcatccgatt aaaaatggct
     9601 atgaattgat aaaagagtac caacagtttc agatttgtaa aatcagtccg caggctgatg
     9661 aagaggaaga tgaacttgtg ttacactatc aaaatcaggt agcttatcaa ggatatttat
     9721 tttcctttgg acttccatta gaaggtgaat caattcaaca aatacctgtt tcacgtgaaa
     9781 catccataca cattcgtcat cgaaaaacag gagatgtttt gattcaaaat gggcatagaa
     9841 aaaaactcag acgtttattt attgatttga aaatccctat ggaaaagaga aactctgctc
     9901 ttattattga gcaatttggt gaaattgtct caattttggg aattgcgacc aataatttga
     9961 gtaaaaaaac gaaaaatgat ataatgaaca ctgtacttta tatagaaaaa atagataggt
    10021 aaaaaatgtt agaaaacgat attaaaaaag tcctcgtttc acacgatgaa attacagaag
    10081 cagctaaaaa actaggtgct caattaacta aagactatgc aggaaaaaat ccaatcttag
    10141 ttgggatttt aaaaggatct attcctttta tggctgaatt ggtcaaacat attgatacac
    10201 atattgaaat ggacttcatg atggtttcta gctaccatgg tggaacagca agtagtggtg
    10261 ttatcaatat taaacaagat gtgactcaag atatcaaagg aagacatgtt ctatttgtag
    10321 aagatatcat tgatacaggt caaactttga agaatttgcg agatatgttt aaagaaagag
    10381 aagcagcttc tgttaaaatt gcaaccttgt tggataaacc agaaggacgt gttgtagaaa
    10441 ttgaggcaga ctatacctgc tttactatcc caaatgagtt tgtagtaggt tatggtttag
    10501 actacaaaga aaattatcgt aatcttcctt atattggagt attgaaagag gaagtgtatt
    10561 caaattagaa agaataatct ttaatgaaaa aacaaaataa tggtttaatt aaaaatcctt
    10621 ttctatggtt attatttatc tttttccttg tgacaggatt ccagtatttc tattctggga
    10681 ataactcagg aggaagtcag caaatcaact atactgagtt ggtacaagaa attaccgatg
    10741 gtaatgtaaa agaattaact taccaaccaa atggtagtgt tatcgaagtt tctggtgtct
    10801 ataaaaatcc taaaacaagt aaagaaggaa caggtattca gtttttcacg ccatctgtta
    10861 ctaaggtaga gaaatttacc agcactattc ttcctgcaga tactaccgta tcagaattgc
    10921 aaaaacttgc tactgaccat aaagcagaag taactgttaa gcatgaaagt tcaagtggta
    10981 tatggattaa tctactcgta tccattgtgc catttggaat tctattcttc ttcctattct
    11041 ctatgatggg aaatatggga ggaggcaatg gccgtaatcc aatgagtttt ggacgtagta
    11101 aggctaaagc agcaaataaa gaagatatta aagtaagatt ttcagatgtt gctggagctg
    11161 aggaagaaaa acaagaacta gttgaagttg ttgagttctt aaaagatcca aaacgattca
    11221 caaaacttgg agcccgtatt ccagcaggtg ttcttttgga gggacctccg gggacaggta
    11281 agactttgct tgctaaggca gtcgctggag aagcaggtgt tccattcttt agtatctcag
    11341 gttctgactt tgtagaaatg tttgtcggag ttggagctag tcgtgttcgc tctctttttg
    11401 aggatgccaa aaaagcagca ccagctatca tctttatcga tgaaattgat gctgttggac
    11461 gtcaacgtgg agtcggtctc ggcggaggta atgacgaacg tgaacaaacc ttgaaccaac
    11521 ttttgattga gatggatggt tttgagggaa atgaagggat tatcgtcatc gctgcgacaa
    11581 accgttcaga tgtacttgat cctgcccttt tgcgtccagg acgttttgat agaaaagtat
    11641 tggttggccg tcctgatgtt aaaggtcgtg aagcaatctt gaaagttcac gctaagaaca
    11701 agcctttagc agaagatgtt gatttgaaat tagtggctca acaaactcca ggctttgttg
    11761 gtgctgattt agagaatgtc ttgaatgaag cagctttagt tgctgctcgt cgcaataaat
    11821 cgataattga tgcttcagat attgatgaag cagaagatag agttattgct ggaccttcta
    11881 agaaagataa gacagtttca caaaaagaac gagaattggt tgcttaccat gaggcaggac
    11941 ataccattgt tggtctagtc ttgtcgaatg ctcgcgttgt ccataaggtt acaattgtac
    12001 cacgcggccg tgcaggcgga tacatgattg cacttcctaa agaggatcaa atgcttctat
    12061 ctaaagaaga tatgaaagag caattggctg gcttaatggg tggacgtgta gctgaagaaa
    12121 ttatctttaa tgtccaaact acaggagctt caaacgactt tgaacaagcg acacaaatgg
    12181 cacgtgcaat ggttacagag tacggtatga gtgaaaaact tggcccagta caatatgaag
    12241 gaaaccatgc tatgcttggt gcacagagtc ctcaaaaatc aatttcagaa caaacagctt
    12301 atgaaattga tgaagaggtt cgttcattat taaatgaggc acgaaataaa gctgctgaaa
    12361 ttattcagtc aaatcgtgaa actcacaagt taattgcaga agcattattg aaatacgaaa
    12421 cattggatag tacacaaatt aaagctcttt acgaaacagg aaagatgcct gaagcagtag
    12481 aagaggaatc tcatgcacta tcctatgatg aagtaaagtc aaaaatgaat gacgaaaaat
    12541 aaccctgaga gaggctggag tctctctttt ttgtgcagtt taggagctaa agggaacaga
    12601 atggagaaaa tggaacaaat gtgttttcta atctgttaga ctgtatctag aaaggggaaa
    12661 attatgatta aagaattgta tgaagaagtc caagggactg tgtataagtg tagaaatgaa
    12721 tattaccttc atttatggga attgtcggat tgggaccaag aaggcatgct ctgcttacat
    12781 gaattgatta gtagagaaga aggactggca gacgatattc cacgtttaag gaaatatttc
    12841 aaaaccaagt tt
//
LOCUS       DAVMCN010000047        12226 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVMCN010000047 DAVMCN010000000
VERSION     DAVMCN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.048"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(51..1253)
                     /gene="rpsA"
                     /locus_tag="VYP85_001595"
     CDS             complement(51..1253)
                     /gene="rpsA"
                     /locus_tag="VYP85_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1882080.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1415..1486)
                     /locus_tag="VYP85_001596"
     tRNA            complement(1415..1486)
                     /locus_tag="VYP85_001596"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1452..1454),aa:Gln,seq:ttg)
     gene            complement(1496..1576)
                     /locus_tag="VYP85_001597"
     tRNA            complement(1496..1576)
                     /locus_tag="VYP85_001597"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1540..1542),aa:Tyr,seq:gta)
     gene            complement(1626..1856)
                     /locus_tag="VYP85_001598"
     CDS             complement(1626..1856)
                     /locus_tag="VYP85_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1882081.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEIFIENYNLAK"
     gene            complement(2024..2668)
                     /gene="pcp"
                     /locus_tag="VYP85_001599"
     CDS             complement(2024..2668)
                     /gene="pcp"
                     /locus_tag="VYP85_001599"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1882082.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2683..3606)
                     /locus_tag="VYP85_001600"
     CDS             complement(2683..3606)
                     /locus_tag="VYP85_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1882083.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3603..4292)
                     /locus_tag="VYP85_001601"
     CDS             complement(3603..4292)
                     /locus_tag="VYP85_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1882084.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4357..5061)
                     /locus_tag="VYP85_001602"
     CDS             complement(4357..5061)
                     /locus_tag="VYP85_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1882085.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5117..6139)
                     /locus_tag="VYP85_001603"
     CDS             complement(5117..6139)
                     /locus_tag="VYP85_001603"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1882086.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6271..8742)
                     /gene="parC"
                     /locus_tag="VYP85_001604"
     CDS             complement(6271..8742)
                     /gene="parC"
                     /locus_tag="VYP85_001604"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1882087.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9162..11105)
                     /gene="parE"
                     /locus_tag="VYP85_001605"
     CDS             complement(9162..11105)
                     /gene="parE"
                     /locus_tag="VYP85_001605"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1882088.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11241..11882
                     /gene="plsY"
                     /locus_tag="VYP85_001606"
     CDS             11241..11882
                     /gene="plsY"
                     /locus_tag="VYP85_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1882089.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(11925..>12226)
                     /locus_tag="VYP85_001607"
     CDS             complement(11925..>12226)
                     /locus_tag="VYP85_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1882090.1"
                     /translation="ILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESFF
                     GILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3514 a         2770 c         2159 g         3783 t
ORIGIN      
        1 gaaaaatccc ttgtttagta aacaaaggat tttgtgaatt ttcaatttga ttaaagttcg
       61 atatcaccaa acaaatcagc cattgaaaat cctgtttgtg tttctggaag ttcgaaatca
      121 cgcttttctt gacgtcttgg acgacgtgga cgagcagcac gtttttcttc tttttgtcct
      181 tcttcttggg ctggacgttc ttcaagagct ttaatagaaa gtgacacgcg ttctgcatct
      241 gcgttaactt caagaacttt aacttgaact tcttgaccaa ctttaagagc ttcttttgga
      301 ttttcaatcc gtttgtgtga aatttgtgat acgtgaacaa gtccatcgat acctggcaat
      361 acttcaacaa atgcaccgaa gtcagtcaaa cgtttaactg ttccttctac tacatcacct
      421 ttagccaatt tttgctcaac gccatcccat ggtcctggta ctgttgcttt aagtgaaagt
      481 gatacacgtc cttcttcttc gttaagatca aggattttca cttcaatttc ttcaccaaca
      541 gttacaactg attttggtga tacgttacgt tcatgtgaca attcagtcaa gtgaaccaat
      601 ccgtcaacac caccaaggtc gatgaaagcg ccgaagcttg tgatacgagc aactttacca
      661 gttacaacat caccaacagc caatttaccg aatacttcag cgcgagctgc tgcagtagct
      721 gcttcaacaa cttcacgacg tgaaaggatg aagcggtttt ctttagcgtt aacttctttg
      781 attttagtat caaattcttg acctacaaaa cgctcagcgt tacgtacgaa acgagtatcc
      841 aacattgaag ctgggataaa tccacgaaca ccttcaaatt ctactgaaag tccaccttta
      901 acggcacgcg ttcctttaac agtaacaact tcttcttcgc gaccaacaag tttgtcccat
      961 gctttgcgag cttcaaggcg ttttttagat acaaggtatg taactgtatc agtatcttta
     1021 ccaactactt gacgaagtac aagaacatcc aatacttctc ctactttaac aaagtcattg
     1081 atatctgcat cacgatcgtt tgtcaattcg cgaagagtca agacaccttc aacaccagtt
     1141 ccagagattg caacgttagc ttgagtcgca tcaactgtca atacttcagc actaacaaca
     1201 tcaccagtct caacttgact aacgctattt agcaaatctt caaattcgtt catctaaaaa
     1261 atcctccaac aatcaagttt ttcttaaact tgacatactt ataatttttt tcctaagcac
     1321 ccgcaaggac atgttcatat cattcacgtc tttcaattat aaaaataaaa taccctaaga
     1381 tattttgctt tctatcttga ttattaccta agaactgggg tagctggatt cgaaccaacg
     1441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccattaa tgaaatggag
     1501 agagagggat tcgaaccccc gaacccgaag gagcggattt acagtccgcc gcgtttagcc
     1561 tcttcgctat ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac
     1621 aagacttatt ttgctaaatt ataattttca ataaaaattt ccacagcttt ttccaatttt
     1681 ttataaaaac tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca
     1741 atttctccga taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca
     1801 acattaactt tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca
     1861 tacctctctt cactttttct attttacaag aaaatcctaa aactagcaag aaaaaactct
     1921 atatcaggct tctctgatat agagttttat gtaaacaacc tcaattgatt tagcatagtt
     1981 aatagttagt aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc
     2041 ctactaactg caaatcctta tctttgtagt ctacaatagc ttcaatagct acctctatgc
     2101 ctcttacaat atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca
     2161 tcatatatgg aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat
     2221 aaagagcttg gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg
     2281 ccggaagtcc ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat
     2341 aggccgatgc tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag
     2401 gtatgcgagc atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc
     2461 ctgcttgtcc aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa
     2521 cttctgacga cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa
     2581 tctcagatgg taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag
     2641 gattaaaacc tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta
     2701 cattaagaat atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac
     2761 gccattctga tctttcatat ccatcaatgc tgctggtaga gcgttaaaat tagcagccat
     2821 tggggtcaat aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg
     2881 attagctccc agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc
     2941 tgcaaaagca tttcccataa tcattgtgaa tagaaccatt ccaagaacat aagccaaaac
     3001 tcctataaag cgactatctg aaggaacaat accgctaatc agatgagaga taacatcacc
     3061 aacacctgct acagtaaaaa tagcccccaa agcccctaat aattgaggaa caatcccact
     3121 tgttgaaact tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt
     3181 ggtaatcaca agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct
     3241 aaattctgga atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat
     3301 aaaaatttta tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg
     3361 caaggttccg atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat
     3421 accaatactc atatttggca tataggaacc acctataaac gtaatagaca atagagtcca
     3481 aaatgcagat gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt
     3541 atggagaaat tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc
     3601 tgtcattttt gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa
     3661 ttgtaaatcc ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc
     3721 cctgcataat tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc
     3781 ccagcaccta caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgcagccgca
     3841 cgcgctttta ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca
     3901 gctgcttctc ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga
     3961 attgaaaaga aaccagctaa ctctcgaata aagaaataaa ctgtatagaa gtttccaact
     4021 gtcagacctt taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct
     4081 gacagcccca caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat
     4141 tcttttccca aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc
     4201 aaaccagcta agactactgt tgcaattgta tcaaatttta aaataaaacc cacaacaatg
     4261 attgctattc ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca
     4321 gtattttaaa aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc
     4381 tttttggtat ttgctattgg attccaattt ttctttttgc cattttttaa aaacctcgtt
     4441 atattctttt gttgtaacaa tatctttttg caatttcatt cctttaaaga tatatggttc
     4501 ccccttaata ccaacttgtg agtatggttt tgagaatggt actacgttac ttacaactgg
     4561 agaaccacca gatgaagctg ttggcatcaa taatgaacta tctgtcgacc aagcttgagc
     4621 tttggcatat ttttcatatc tcttctctag gtcagtggtc tcagaaacag catcttctaa
     4681 caatttctta tatttatcca aaccaggttt agctacaaca tccttatctt ttcctttcgt
     4741 aatgccaagg tgtttcatgg cagaaccaga ttttggatcc ataatattca agtaagacgc
     4801 tggatcttga tagcttggag cccatcctgt actattcaaa tcatagtctt tttgagaagg
     4861 agcaacattg ccgtatttat cattttccat caaaccatca ataacatttc caataacgtc
     4921 tgtcgtcgat gttcgagtcg ctatactgta gcccaatgat gctggatcta ctgcatagac
     4981 ataagaaaat gttgtcggtg catctgcttc tttatcagtt tttccacaag ccactaaaat
     5041 agctgacgtg ctcaggacca ctcctgctgt taagagccgc tttttctatt tcataaaaaa
     5101 tctcctttgg tttattttaa tctactttta caatccaacc ttctggcgct tcaatatcgc
     5161 caaactgaat acccgtcaat tcattatata atttacgcgt cacaggacct acttctgttt
     5221 cactatagaa tacatggaaa tcatcaccat gttgaatacc tccaattgga gaaataaccg
     5281 ctgctgtacc acaggcacct gcctctacaa aacggtcaag attatcaatt ggaacatcac
     5341 cctcaatagg agttaatccc aagcgatgtt ctgccaaata aagcaaggaa tacttggtaa
     5401 tagatggcaa gatagatgga ctcaatggtg ttacaaattc attatcagct gtaattccaa
     5461 agaagttagc tgatccgact tcttcaatct ttgtatgagt tgatgggtcc agatagataa
     5521 catctgagaa atgacgtgac ttggccattt ttcctggtaa gagacttgca gcatagtttc
     5581 caccaacctt agccgcacct gtaccatttg gtgctgcacg gtcgtactca tcctgaatca
     5641 agaagttggt tgggaccaaa ccacctttaa agtaatttcc aactggcata gcaaagatgg
     5701 tgaaaatgta ttcttctgcc ggttttaccc cgataatatc tccgacacca atcaaaagag
     5761 ggcgaagata taaggttcca cctattccgt atggtggtac gtattcttca ttcgcacgga
     5821 caactgcttt acaagcttct acaaacatgt ctgtcggaac ttgtggcatc aagagacggt
     5881 cacatgtacg ttgcaggcgt ttagcatttt catcaggacg gaacagttga acactgccat
     5941 ccttagtacg ataagctttc aaaccttcaa atgcttgttg tccatagtga agacttggag
     6001 aagactctga aatatgcaaa gttgcatcct ctgtaagctc tccttgatcc cattgtccat
     6061 ttttgaaatg agcaagatag cgataaggta atttcatata ggaaaaaccg aggttttccc
     6121 aatcaatcgt tactgtcata ttccactcct tattctaaaa acctatttct tatattctac
     6181 actatttttc taaaatagca agtatatttt gtaattttca gaaaatttct ccaataaaaa
     6241 ccagctctta gaactgattc ttcatttcac ttatttatct tcagtaacta cttcctgaag
     6301 ataagcgtca aaaacttctt catctgaaat cgtgtcagaa atgaagcttc cattgctagt
     6361 gcgttctgac aagttcaagt cttgcaatcg gctttcatag attgttcctt tattggattg
     6421 gacaagcaga gtttggtcgt tcacatccac ttccgtactg aagaaatcgc caacaaatcc
     6481 ttgctctgca actgctcctg ccaagaagac acgatgcggt ttgtttttca actcacgcaa
     6541 gacttgtaat cctcgtttgg cacggctggt tgctagaatt tcctcaatgg aaacacgttt
     6601 caagcttcca cgctgggtca agaggtagaa ggacgaagta ttacagataa agccagattg
     6661 gaggacatca tcttctttca aattcatagc cttgacacct gctgccttag caccgacaac
     6721 cggaacctct tcgatattga aacgcagggc ataaccattt tgactaacca agacaacatc
     6781 atctagttta atcggagcca ctgctacaat ctgatctgta tcgtctttga gcttagcata
     6841 cttgacagac ttagatctat aggtccgcca tggagtgaat tcttttcgct ctacccgttt
     6901 gatttgacca aggcgagtcg ctgcaaagta ggttgtcgca tcgtcaaact gatccagtac
     6961 ttccacataa aggattgctt cattcgtttc aaagtttgtg atggtttggc tcagatgctc
     7021 tccgatgtcc ttccaacgaa tatctgccaa ctcatggatt ggtctgtaga tgacatttcc
     7081 aagacttgtg aacatcaaga ggtgctgggt tgtcttggca gattgaacaa aaatcaaacg
     7141 gtcatcatca cgcttgccaa tttcttccaa ggtggaagcc gcaaaggaac gtggactggt
     7201 acgcttgatg taacctgcct tggtcacgct gacgtaggta tcttcctcag cgataagact
     7261 agctgtatca atctcaattg ctttcgcagt gtcttctaaa gaactcaaac gaggagttgc
     7321 aaatttcttc ttgacctcac gaagttcttt cttcatgaga ttgtacatag tcctttcatc
     7381 accgataata gccaccagca tagcaatctt ctcacgaagc tctgcttctt cttcctgcaa
     7441 gacaaccaca tcggtattgg tcaaacggta cagttgcaaa gttacgatag cctcagcctg
     7501 ttcttccgta aaatcatagc taactttgag gttttccttg gcgtccgcct tattctcaga
     7561 agcacggata agagcaatga cttcatccaa aatcgaaatc acacgaatca aaccttcgac
     7621 gatatggaga cgtttctcag ccttttcttt gtcaaagcgt gaacgcgcca aaatcacttc
     7681 tcgacggtga gcgatgtagc tagacaggat tggaacaatc ccaacctgac gaggtgtgaa
     7741 attgtcaatc gccaccatat taaagttgta gttgatttgt aggtcggtgt acttaaataa
     7801 gtagttgaga acaagctcag tattagcgtc tttcttaagt tcgatagcga tacgaagacc
     7861 atcacggtca gactcatcac gaacctcagc aatcccagct accttgttat taacacgaac
     7921 atcatcgatt ttcttgacta gattggcctt attgatttca taaggaatct cagtaataac
     7981 gatttgttcc ttaccacctt ttagcttttc aatttcagtc ttggaacgaa caaccacgcg
     8041 ccctttccca gtctcataag ctttcttgat ttcatcacga ccctgaataa tagcccctgt
     8101 agggaagtct ggtccaggca agaattccat gagtttatca atctttgcag ttgggtggtc
     8161 aatcatgtaa actgcagcat ctatgacctc agctaaatta tggggaggaa tgtctgtggc
     8221 ataaccagcc gaaatcccag tcgaaccatt gaccaagagg tttggaaagg ctgctggcaa
     8281 gaccgttggt tctttctccg tatcgtcaaa gttccatgca aaaggaactg tctttttctc
     8341 gatatcctga agaaggtagc ctgcaatttc agacaaacgt gcctcagtat aacgcatagc
     8401 cgcaggagga tctccgtcca tagaaccgtt attaccgtgc atttcaacta gaatctcacg
     8461 atttttccag ttctgtgaca tacgaaccat ggcgtcatag atagaagaat ccccgtgtgg
     8521 gtggaaattc cccatgatgt tcccgactga cttggccgac ttacggtagc tcttgtcaaa
     8581 agtattgcta tccttattca tagaataaag aatacggcgc tgaaccggct tcaacccatc
     8641 acgaatatct ggcaaagccc ggtcttgaat aatgtacttg gagtagcgac caaagcgctc
     8701 tcccatgatg tcctccaggg acatgttttg aatgttagac ataagataca aagcccataa
     8761 aataccaagt gaaaatagaa aattcttgaa gtaagcaaac tcacaagaga atttatcttt
     8821 ttcacacagt atctagggcg tgttcaactc ctttcaaaga atgtagagta ggtttttatg
     8881 cagtaaaaga tattttacgg gaattcgtcc cgtgttcagt tacgataagt aaccaaacta
     8941 tcctgtttgt atttttcaat atgaaaatat ggttttccaa aattagtctt agtttgtgtc
     9001 ttagccgctc ccttaaacgc ctctttgaga taagcactca tagcagattc ttcattaata
     9061 atcctgcaat tttttcaaac caagattttc aaactgcttt ttcacatagt cattcacatc
     9121 cgactctaat ttccagttta ctaacatatt attttctttc attaaaacac tgtcgcttct
     9181 tctagcgtaa acttgacatt atcttcaatc catttacggc gtggttctac cttatctccc
     9241 atgagaacat tgacgcggcg ttcggcgcgc gctaaatctt caattgtgac acggatgagg
     9301 gtacgtgttt ctgggttcat ggttgtttcc cagagctggt ccgcattcat ctcaccaagt
     9361 cctttgtatc gttggagggt agcgccttta ccgaactgtt tacggagttc ttctagttct
     9421 ccgtccgtcc aagcgtaggc cacttcttct ttcttgcctt tacctttgga catcttgtaa
     9481 agaggtggga gggcaatata gacatgacct gcctcgacta gcggacgcat gtaacggtag
     9541 aaaaatgtca agagcaaggt ctggatatgg gcaccgtcgg tatccgcatc ggtcatgata
     9601 atgatcttat catagttggc atcttcaata gagaagtctg ctccaacacc cgcaccaatg
     9661 gtataaatca tggtattgat ctcttcattt ttgaggatat ccgccatctt ggccttggct
     9721 gtattgacaa ccttaccacg aagaggtaga atagcctgga acttgcggtc acgaccttgt
     9781 ttggcagaac caccggcaga gtccccctca actagataga gttcattctt agcaggattc
     9841 ttagattggg ctggggtcaa tttcccagac aacaagccct tatctttctt gtttttcttc
     9901 ccatttcggc tctcatcacg cgccttacgt gctgcttcac gagcatcacg ggccttgata
     9961 gccttgcgga tgaggttaga agctaattcc ccattttcca taaggaaaaa ggtcaactta
    10021 tcagccacta ttccatccac aactgggcga gctagggggc ttcctagttt atccttggtc
    10081 tgtccttcaa actgcaagtg ttcttcagga actaagatag aaagaacggc cgctagtccc
    10141 tcacgatagt ctgaaccttc aaggttttta tctttttcct tgagaagacc tgttttacgt
    10201 gcatagtcat tcatgacctt ggtaatggca gacttgagtc ctgtctcgtg cgttccaccg
    10261 tccttggtgc gaacgttatt gacaaaggat agaatgttat ctgagaatcc gtcattgtac
    10321 tggagggcta cttccacttg aaaaccattg tcttcccctt caaagtaaag aactggcgtc
    10381 aagatttcct tatcttcgtt gagataagaa acaaaatctt gtactccatt ctcatagtgg
    10441 aactcaatcg cttcatctgt tcgcttgtcc gttaaagaca aggtcacatt tttcaagaga
    10501 aaggctgatt cattaaggcg ctctgaaatg gtattgtact tgaaatctgt cgtagaaaag
    10561 atagtcgcgt caggcataaa agtaactttg gtgcctgttt tagacttggg tgctgtaccg
    10621 attttcttca aagtcgtgac aggttttcca ccattttcaa aacgttgctt gtaaactgcg
    10681 ccatcacggg taatttcaac ttctaaccag ctagaaaggg cgttaacaac ggaagaaccc
    10741 actccgtgaa gtccacctga tgtcttatag ccaccttgac cgaatttccc tccggcatga
    10801 agaatggtaa agataacctc aacagttgga attcccatag cgtgcatacc tgtcggcatc
    10861 ccacgtccat ggtcttgaac cgttagacta ccgtctttat tgatagttac atcaatacga
    10921 tcaccaaacc cagacaaggc ttcatcgact gcattatcaa cgatttccca aactaggtga
    10981 tgaagaccag cgccatcggt cgatccaata tacatccctg gacgttttcg gaccgcatcc
    11041 aacccttcta gcacctgaat agcatcatca ttataattgt taatattgat ttcctttttt
    11101 gacacaagga acctcctatt cgttcatctt tactattcta caggttttcc aaggattttg
    11161 caaaattttt ctttctccga tgtgacaatt tcagcagaga ttctctgctt ttctttccca
    11221 attcatgata taataggagt atgattacaa tagttttatt aatcctagcc tatctgctgg
    11281 gttcgattcc atctggtctc tggattggac aagtattctt tcaaatcaat ctacgcgagc
    11341 atggttctgg taacactgga acgaccaaca ccttccgcat tttaggtaag aaagctggta
    11401 tggcaacctt tgtgattgac tttttcaaag gaaccctagc aacgctgctt ccgattattt
    11461 ttcatctaca aggcgtttct cctctcatct ttggactttt ggctgttatc ggccatacct
    11521 tccctatatt tgcaggattt aaaggtggta aggctgtcgc aaccagtgct ggagtgattt
    11581 tcggatttgc gcctatcttc tgtctctacc ttgcgattat cttctttgga gctctctatc
    11641 ttggcagtat gatttcactg tctagtgtca cagcatcgat cgcggctgtt atcggggttc
    11701 tgctctttcc actttttggt tttatcctga gtaactatga ctctctcttc atcgctatta
    11761 tcttagcact tgctagtttg attatcattc gtcataagga caatatagct cgtatcaaaa
    11821 ataaaactga aaatttggtc ccttggggat tgaacctaac ccatcaagat cctaaaaaat
    11881 aaaacgccag ttctgtactg accccaaaaa gttagacaat taatttatcc gaaggattta
    11941 gttctgtatt gcacagggct aagtcctttt agttttacct taattcgttt attgttgtag
    12001 taatcaatat agtctacaat ggcttgttcc aattgcttaa gcgactgaaa cgacttctca
    12061 taaccgtaaa acatttccga tttcagaatc ccaaagaagg actccatcat accattgtct
    12121 gggctgttac ccttacgtga catggatgct tgaattccct taccctcaag aaactgatga
    12181 taagaatcgt gttgatattg ccagccttgg tcactatgga gaatcg
//
LOCUS       DAVMCN010000048        11952 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVMCN010000048 DAVMCN010000000
VERSION     DAVMCN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.049"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            174..443
                     /gene="blpJ"
                     /locus_tag="VYP85_001608"
     CDS             174..443
                     /gene="blpJ"
                     /locus_tag="VYP85_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1882091.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            512..742
                     /gene="blpU"
                     /locus_tag="VYP85_001609"
     CDS             512..742
                     /gene="blpU"
                     /locus_tag="VYP85_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1882092.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            745..864
                     /locus_tag="VYP85_001610"
     CDS             745..864
                     /locus_tag="VYP85_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1882093.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1161..1322
                     /locus_tag="VYP85_001611"
     CDS             1161..1322
                     /locus_tag="VYP85_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882094.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIVYMIAVMIYF
                     SLIKKKEKK"
     gene            1332..1703
                     /locus_tag="VYP85_001612"
     CDS             1332..1703
                     /locus_tag="VYP85_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882095.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            2332..2715
                     /locus_tag="VYP85_001613"
     CDS             2332..2715
                     /locus_tag="VYP85_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1882096.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2767..3456
                     /locus_tag="VYP85_001614"
     CDS             2767..3456
                     /locus_tag="VYP85_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1882097.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRELLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3498..3731
                     /locus_tag="VYP85_001615"
     CDS             3498..3731
                     /locus_tag="VYP85_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882098.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3882..4493
                     /locus_tag="VYP85_001616"
     CDS             3882..4493
                     /locus_tag="VYP85_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1882099.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4655..5449
                     /locus_tag="VYP85_001617"
     CDS             4655..5449
                     /locus_tag="VYP85_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1882100.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5446..6081
                     /gene="trmB"
                     /locus_tag="VYP85_001618"
     CDS             5446..6081
                     /gene="trmB"
                     /locus_tag="VYP85_001618"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1882101.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6207..6686
                     /gene="rimP"
                     /locus_tag="VYP85_001619"
     CDS             6207..6686
                     /gene="rimP"
                     /locus_tag="VYP85_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1882102.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6730..7866
                     /gene="nusA"
                     /locus_tag="VYP85_001620"
     CDS             6730..7866
                     /gene="nusA"
                     /locus_tag="VYP85_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1882103.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7888..8181
                     /locus_tag="VYP85_001621"
     CDS             7888..8181
                     /locus_tag="VYP85_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1882104.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8174..8473
                     /locus_tag="VYP85_001622"
     CDS             8174..8473
                     /locus_tag="VYP85_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1882105.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIEDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8490..11255
                     /gene="infB"
                     /locus_tag="VYP85_001623"
     CDS             8490..11255
                     /gene="infB"
                     /locus_tag="VYP85_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1882106.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAEPVAPKTEKVAAKPQSRNFK
                     AEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQ
                     QGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKE
                     ALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRD
                     DYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFH
                     ELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYG
                     IEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRV
                     ATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDG
                     VMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVE
                     ISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGT
                     LNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEK
                     SARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSA
                     SLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVE
                     IRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKV
                     ARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAY
                     VMEEIKR"
     gene            11506..11856
                     /gene="rbfA"
                     /locus_tag="VYP85_001624"
     CDS             11506..11856
                     /gene="rbfA"
                     /locus_tag="VYP85_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1882107.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3651 a         2085 c         2694 g         3522 t
ORIGIN      
        1 agatactcaa gattattgaa atcttagact aaaaaatagg tactgctact tttaagaaga
       61 tagtagacgt atatactttt ttaagaaaat caaaaagata ctataaaaaa tctatttgtt
      121 tattgaattt aagactttgg taacaaattg aaaataaaaa ggaggtattc atcatgaata
      181 caaaaatgtt gtcacagtta gaggttatgg atactgaaat gcttgcgaaa gttgaagggg
      241 ggtatagctc cactgattgt caaaatgcac tgattacagg agtcactacg ggaattataa
      301 ctggtggaac tggagcaggt ttggccactt taggagtagc tggacttgct ggtgcatttg
      361 ttggagcaca cattggtgca attgggggtg gattaacatg cttaggaggt atggttggtg
      421 ataaattggg actaagttgg taagacttat agtaaaatta tgaggattct attctgattt
      481 attttagttt tttaaaaaag gagtatttgt catggataca aaaatgatgt cacaattttc
      541 tgttatggat actgaaatgc ttgcttgcgt tgaaggtggc ggatgcaatt ggggagattt
      601 tgccaaagca ggtgttggag gagcagcagc aagaggtctt caactaggca ttaaaacagg
      661 aacatggcaa ggtgcagcaa ctggtgctgc gggtggagct atacttggag gtgtagccta
      721 tgcagcaaca tgttggtggt aattatggat tttaaaagtt ttattattgg tttagtagtt
      781 ggtatatttg gtccttatat ggataattta attagaaaaa tattttcaaa atttcccaaa
      841 aaggatacag atagtacccc ctaaaaaata aatttttccc ctgtatttgc tagcttaatt
      901 tacaggggag tttctttaat attgtttcgc ctgtcaaaat gatatgtgat agcaggatga
      961 aaagtctaca aacaagttgg tatcaataca atataaagag gaaagtatgt ttttcatgct
     1021 tgctttttta atttttacaa ttcaagaggt tttgatgacc atttatgatt tgagtgatcc
     1081 aaggtcaaaa taagtgctat actagcagtg taaatgttct tgctcaacta agataaatcg
     1141 cacatttagg aggaaatctt atgaagaaaa aaatactgat tattttcgtt ctgtatctaa
     1201 tcatgtccat ctttctatat ccgcttaggg agagtgcttg gtatcagcta ttttatacca
     1261 tagtctatat gattgcggtt atgatctatt tttctttaat taaaaagaaa gaaaagaaat
     1321 gaaagatttt cttgattaaa aagaatcata ttctttgtga gattgttcct gggtcagttg
     1381 cctttgcttg tttctactta tctatttcta tttcgtcagt tttccaattt cttttagtgg
     1441 ttattaactt gacttctatt ttggttactg tttatcttac tagggaaatg agattaagag
     1501 agtttgaaga tgatgatttg gttagtccta gaaccaatca actcatgttt atcggcttga
     1561 caggctttat gtctattatt tgtttgtata gagggatcac agcaggagaa tcctaccaac
     1621 aaataattgc ctacattggc gctattctct gcttgaccat catgcttctg ctcatttggg
     1681 gattgaagta ttataaaaag tagaggctaa tgcagttttt gcaatttaag atgtcttgat
     1741 gacaattcaa gatttggatg aaaaactttg acaaatagtg ctatactgaa attgtcaaag
     1801 ttgcaacggg tgctgctaca ttatgttaaa aatcgctctt gattgataag ctggatttgt
     1861 taggaaagga gtaaataatt atggataaga aaaagatagt ttcgactata atatgtatag
     1921 tatttcttgt agtgtcagta gataattttt ttagagactt aaccccgtta ctgttcattt
     1981 taaatattat tggtctgtct tgcttttcag tgctaacata cactaacata aaagagatac
     2041 tcttaaatat aagtaaatga tgatttggtt agtcctagaa ccaatcaact tatgtttatc
     2101 ggcttggcag attttatgtt tgtcatttgt ttgtatagag gtatttcaga aacagaattc
     2161 tatcaacaac taatcgttta tataggtgta ttctctgctt gtttatcacg cttctgctca
     2221 tgtggggctt gaagtattat aaaaagtagc tttctatcct tttctgacag gatatttgag
     2281 tagaaggctc tattaaattg ttagtgaaat aaatgaatgg aggtatttaa tatgaaatac
     2341 agattatttt ttgttatttt cttgagtagt gtgttggata ttcttttagg gacattttta
     2401 caaatctcta tcgtatctat tgggtggctt gttctttaca gtggtttgtt tgaagcagga
     2461 gttttccttc ttgctaataa aggggtggcg gtaaaaatca aggaagtaga tattcgaaat
     2521 cgctttaaat ttatttttgg aaaaacctta tggtttcaaa ttcttttgct catctttttg
     2581 ataatcaaac tttatcttgg tttggatgcg aggttgattt tattctatgg acatattttc
     2641 attgtcttta atgccttaat gtatctatta tctagtagtc aggttagcct taaaaaaaac
     2701 aaactgtctt cttaatctta cagcagtaga gcctgacaag gtgaggtcat agtagggagg
     2761 atttctatga aaaagtatca acttctattc aaaataagtg cagtcttctc ttacttattt
     2821 ttcgtatttg gtctttctca gctgacgctt atcgtccaaa attattggca attttcttcc
     2881 cagattggta atttcgtctg gattcaaaat atcttgagtt tactttttat tggagtcatg
     2941 attgtggttc ttgttaagac aggccatggt tatctcttcc gcattccaag aaaaaaatgg
     3001 ctttggtatt cgattttgac agtattagtg gtagtgttcc agatctcttt taacgttcag
     3061 acagctaaac atgttcagtc aactgcggaa ggttgggctg tattgattgg ttatagtggg
     3121 actaactttg cagagctagg tatttatata gccctgttct ttctggttcc actgatggaa
     3181 gagttaatct atagagaatt actgcaacat gctttcttta agcattcgcg atttggtctt
     3241 gatttgcttc ttccttctat tttatttgct ctccctcatt tttcaagcct gcctagtctg
     3301 ttagatatct tcgtctttgc aacagttgga atcatctttg ctggtttgac ccgctatacc
     3361 aagagcattt atccatccta tgcggtgcat gtgatcaata atattgtagc gaccttcccg
     3421 tttttgctca cttttctaca tagggtcttg gggtaaaaaa acaaaaggct tgcttttcag
     3481 ccatagagga ggtcatcatg tataaacact tatttttcct agattccaaa actttagatc
     3541 ggttgacacc ctatattcta gtcttggctt ctgacaccat tgcttttaat gtttttgtgc
     3601 taacctttgt atctgcggtg gtttttaatt tcctaaattc catgctagct ttaatggcta
     3661 tattcatagg ggctggctat gtggtcggat tttggttact aatactcaat gaaaatcaaa
     3721 gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg
     3781 gtttgaattt gattttcgaa gagtataaaa tggtttgttt tggaaaggct agaactaaag
     3841 aatgacgtgt aggaagtctg tttgttgagg aggataattt tatggagttt tttgataaat
     3901 ttcatgcctt gtgttttgga tttttagtac taataattgt cattatagtt ccttatacga
     3961 ttaaccatgg ggattttttt caaaatgaat ctgcattgat tcttgtaagt cttcttgtaa
     4021 cctcgctgag tgttgcttat gctagaaagt ttgaaatgat ttcttttggg atgttaagca
     4081 agaaacaact tttgcttttc attgcaatct ttcttctaag tgtacttgag acgctggttt
     4141 atattcattt cttcgctgtt tcttctggct caggggtcca acacttggcg gaagtcagca
     4201 gaggaatttc cctgtctttg attttgacta cctcagtttt tggccccatc caggaggaac
     4261 tcattttcag aggacttctt caaggtgcgg tttttgacaa ttcttggtta gggcttgtgc
     4321 taacttcctc tctcttttct ttcatgcatg gaccttctaa tgtcccttcg tttatttttt
     4381 atctacttgg gggcttgttg ctgggccttg cttataaaaa gagccaaaac ttatgggttt
     4441 ctactctagt ccatatgctt tacaacagtt ggccactctt atattattta taaaaatcat
     4501 gaaaaggtaa gtaggagatt gtgcttacct ttttctttct ataatgataa cccaaaccac
     4561 tccagaggct tttctttgag aatcgggtta gagtggttga cgaataggcc aaaaactagt
     4621 agaatagtaa ggaaacttta tacggaggaa agaaatggat ttgggtgata atgagctaac
     4681 actgactccc atacctggga aaagtggcaa ggcttatatg ggtagctatc ctgatgggaa
     4741 gcgcatcttt gtaaaaatga acacctctcc aatcctacct ggtctagcta gagaacaaat
     4801 tgctccacaa ttattatgga gtcgtcgttt ggcagatggg cgtgatatgt gtgctcaaga
     4861 atggttgaca ggcaagatat tgacccccta tgatatgaat cgtaagcaaa tcgtcaatat
     4921 tttaacccgt cttcatcgct cacgtccgtt gatgacacaa ttgagtcgtt tgggctatgc
     4981 catggaaaca cctgtagatt tactacagtc ttggcaagaa acggctccag atgctttgcg
     5041 taaaaatcat tttatcagtg aagtgatggc tgatttacgt cagactattc caggatttag
     5101 agaggaccat gcgaccattg tccatggaga tgtacgacat agtaattgga ttgagacaga
     5161 tagtggcttg atttatttag tagattggga ttcggttcgc ttgaccgatc gcatgtttga
     5221 tgtggcccat atgctctgcc attatatttc agaacatcag tggaaggaat ggttgaccta
     5281 ctacggttac aagtacaatc aaacggtatt aagtaaattg tattggtatg gtcaattgtc
     5341 ttatttgagt cagatttcca agtattatat gaaccaagat ttagaaaatg tcaatcggga
     5401 gattcatggt ttgcgtcatt tccgagacaa gtatggaaag agaagatgag agttagaaat
     5461 cgtaaagggg caacagaatt actagaggca aatccccagt atgtggtcct caatcccttg
     5521 gaagccaagg caaaatggcg ggacttgttt ggcaatgata atcccattca tgtggaagtt
     5581 ggaagtggaa agggtgcctt tgtttcaggt atggccaagc aaaaccctga catcaactat
     5641 atcgggattg atattcaaaa gtctgttttg agctacgctt tggacaaggt gcttgaagtt
     5701 ggagtgccta acatcaagct cttgtgggta gatggttctg acttgactga ctactttgaa
     5761 gacggtgaga ttgatcgctt gtatctgaac ttttcagatc catggccgaa aaaacgccat
     5821 gaaaagcgtc gtttgaccta caagaccttt ttggatacct tcaaacgtat cttgcctgaa
     5881 aatggagaaa ttcatttcaa gacggataac cgtggcttgt ttgagtacag tttagtgagc
     5941 ttttctcaat atggcatgaa actcaatggt gtctggctag atttgcatgc cagtgatttt
     6001 gaaggcaatg tcatgacaga atacgagcaa aaattctcaa acaaggggca agttatctac
     6061 cgagttgagg cagaatttta agagatagcc taaaattagg ctgtacaagt gcttttgctt
     6121 tacataagtt ggcaaacgtg ctatactgat agtaagaata tgaaaagtga ggcggggaaa
     6181 tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc aacaatcgta gaattagtca
     6241 gagaagttgt agaacctgtc atagaagctc cttttgaact cgtggatatc gagtatggaa
     6301 agattggcag tgacatgatt ctcagtattt ttgtagataa acccgaagga attaccttga
     6361 acgacacggc agacttgaca gaaatgatca gtcctgtcct agacaccatc aagccagatc
     6421 ccttcccaga acaatatttc ctagaaatta ccagtccagg tttggaacgt cctttgaaaa
     6481 ccaaggatgc cgtcgctgga gcggttggaa aatacatcca tgtcgggctc taccaagcca
     6541 tcgataagca aaaggtcttt gaaggaacct tgttggcctt cgaagaggac gagttgacta
     6601 tggaatatat ggacaagacg cgtaagaaaa ccgtccaaat tccatacagt ttagtatcaa
     6661 aagcacgttt agcagttaaa ttatagaaaa agaaaggata gcttttgagg attcaaaagt
     6721 gaagaaaaca tgagtaaaga aatgctagag gccttccgca ttttggaaga agacaaggga
     6781 atcaaaaaag aagatatcat cgacgcagta gtagagtcgc ttcgttccgc ttatcgcaga
     6841 cgctatggtc agtcagacag cgtagctatt gacttcaacg aaaaaacagg tgactttaca
     6901 gtttatactg tccgtgaagt tgttgatgaa gtatttgata gccgtttgga aatcagcttg
     6961 aaagatgctc ttgccattaa ttcagcttat gaacttggag acaaaatcaa gtttgaagaa
     7021 gcaccagctg agtttggtcg tgtagcagcc caatctgcca aacaaaccat catggaaaaa
     7081 atgcgcaagc aaacacgtgc catcacttac aatacttaca aagaacatga gcaagaaatc
     7141 atgtctggta cagtagaacg ctttgacaac cgctttatct atgtcaacct tggtagcatc
     7201 gaagcccaat tgtcaaaaca agaccaaatt cctggagaag tttttgcttc tcatgatcgt
     7261 atcgaagttt atgtttacaa ggttgaagac aaccctcgtg gtgtgaacgt ctttgttagc
     7321 cgtagccatc cagaaatgat caaacgtttg atggagcaag aaattccaga agtttatgat
     7381 ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg accgtacgaa ggttgctgtt
     7441 cgtagccaca atccaaacgt ggatgctatc ggtacaatcg ttggacgtgg tggtgctaat
     7501 atcaagaaga ttactagcaa attccaccca gctcgttacg atgctaaaaa tgaccgcatg
     7561 gtaccaatcg aagaaaatat cgatgttatc gagtgggtag cagatccagc tgaatttatc
     7621 tacaatgcca tcgctcctgc tgaggttgac caagttatct ttgatgaaaa cgacagcaaa
     7681 cgtgccttgg tggttgttcc agataacaag ctttctcttg ccattggtcg tcgtggacaa
     7741 aacgtgcgct tggcggctca cttgactggt taccgtatcg atatcaagtc tgctagcgaa
     7801 tttgaagcca tggaagacgc tgcttcagta gagttggaag tagaaaacga tactgtagaa
     7861 gaataaaagc tgctagagga gggaaagatg aaaacaagaa aaatcccttt gcgcaagtct
     7921 gttgtgtcta acgaagtgat tgataagcgt gatttgctcc gcattgtcaa gaacaaggaa
     7981 ggacaagtct ttattgatcc tacgggcaag gccaatggcc gcggcgctta tatcaaacta
     8041 gacaatgcag aagccctaga ggcgaaaaag aagaaggtct ttaaccgcag ctttagcatg
     8101 gaagtggaag aaagctttta tgacgagttg atcgcttatg tggatcacaa agtgaaaaga
     8161 agagagttgg gacttgaata agcaaaagat aagtaatctc ttggggcttg ctcagcgagc
     8221 agggcgcatc atatcgggtg aagaattggt ggtcaaggcc attcaagacg gcaaggccaa
     8281 gttggtcttt ctagctcatg atgctggacc caatctgacc aagaagattg aagataaaag
     8341 tcattattat caagtagaaa ttgtaaccgt gttttcaaca ctggaattaa gcatagcagt
     8401 cgggaaatcg agaaaggttt tggctgtaac agatgctgga tttacaaaga aaatgaggtc
     8461 tcttatggaa tagaagagga ggacatgatt tgtctaagaa aagattgtac gaaatcgcaa
     8521 aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc aaaagagttg ggcttggatg
     8581 tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc aaaaattgct gccagcttta
     8641 agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc accaaaagta agtgcagaaa
     8701 agaaagccga aaaatctgag ccagctaaac cagctgagcc agtcgctccg aaaacagaaa
     8761 aagtagcggc taaaccgcaa agtcgtaatt tcaaggctga gcgtgaagca cgtgctaaag
     8821 agcaggcaga gcgacgcaag caaaataagg gcaataaccg tgaccaacaa caaaacggaa
     8881 accgtcagaa aaacgacggc cgtaatggtg gaaaacaagg tcaaagcaac cgcgacaatc
     8941 gtcgctttaa tgaccaagct aagaagcagc aaggtcagca aaaacgtaga aatgagcgcc
     9001 gtcagcaaga ggataaacgt tcaaatcaag cggctccacg tattgacttt aaagcccgtg
     9061 cagcagccct aaaagcagag caaaatgcag agtacgctcg ttcaagtgag gaacgcttca
     9121 agcagtatca ggctgctaaa gaagccttgg ctcaagctaa caaacgcaag gaaccagagg
     9181 aaatctttga agaagcggct aagttagctg aacaagcaca gcaagttcaa gcagtggttg
     9241 aagtcgtccc tgagaaaaaa gaacctgcag tggatacacg tcgtaaaaaa caagctcgac
     9301 cagacaaaaa tcgtgacgat tatgatcatg aagaagatgg tcctagaaaa caacaaaaga
     9361 atcgaagtag tcaaaatcaa gtgagaaatc aaaagaatag taactggaat aacaacaaaa
     9421 agaacaaaaa aggcaataac aagaacaacc gtaatcagac tccaaaacct gttacggagc
     9481 gtaaattcca tgaattgcca acagaatttg aatatacaga tggtatgacc gttgcggaaa
     9541 tcgcaaaacg tatcaaacgt gaaccagctg aaatcgttaa gaaacttttc atgatgggtg
     9601 tcatggccac acaaaaccaa tccttggatg gggaaacaat tgaactcctc atggtggatt
     9661 acggtatcga agccaaacaa aaggttgaag tggataatgc tgacatcgaa cgtttctttg
     9721 tcgaagatgg ttatctcaat gaagatgaat tggttgagcg tccaccagtt gttactatca
     9781 tgggacacgt tgaccacggt aaaacaaccc ttttggatac tcttcgtaac tcacgtgttg
     9841 cgacaggtga agcaggtggt attactcagc atatcggtgc ctaccaaatc gtggaaaatg
     9901 gtaagaagat taccttcctt gatacaccag gacacgcggc ctttacatca atgcgtgcgc
     9961 gtggtgcttc tgttaccgat attacgatct tggtcgtagc ggcagatgac ggggttatgc
    10021 ctcagactat tgaagccatc aaccactcaa aagcagctaa cgttccaatc atcgtagcca
    10081 ttaacaagat tgataaacca ggtgctaacc cagaacgcgt tatcggtgaa ttggcagagc
    10141 atggtgtgat gtcaaccgct tggggtggag attctgaatt tgttgaaatc tcagctaaat
    10201 tcaaccaaaa tatcgaagaa ttgttggaaa cagtccttct tgtagctgaa atccaagaac
    10261 tcaaggcaga cccaacagtg cgtgcaatcg gtacggttat cgaagcgcgc ttggataaag
    10321 gaaaaggtgc ggtcgcaacc cttcttgtac aacaaggtac cttgaatgtt caagacccaa
    10381 tcgttgtcgg aaataccttc ggtcgtgtcc gtgctatgac caacgacctt ggtcgtcgtg
    10441 ttaaagttgc tggaccatca acaccagtct ctatcacagg tttgaacgaa gcaccgatgg
    10501 cgggtgacca ctttgccgtt tacgaggatg aaaaatctgc gcgtgcagca ggtgaagagc
    10561 gtgccaaacg tgccctcatg aaacaacgtc aagctaccca acgtgttagc cttgaaaacc
    10621 tctttgatac ccttaaagct ggggaactca aatctgttaa tgttatcatc aaggctgatg
    10681 tacaaggttc tgttgaagcc ctttctgcct cacttcaaaa gattgacgtg gaaggtgtca
    10741 aagtgactat cgtccactca gcggtcggtg ctatcaacga atcagacgtg acccttgccg
    10801 aagcttcaaa tgcctttatc gttggtttca acgtacgccc tacaccacaa gctcgtcaac
    10861 aagcagaagc tgacgatgtg gaaatccgtc ttcacagcat tatctacaag gttatcgaag
    10921 agatggaaga agctatgaaa gggatgcttg atccagaatt tgaagaaaaa gttattggtg
    10981 aagcggttat ccgtgaaacc ttcaaggtgt ctaaagtggg aactatcggt ggatttatgg
    11041 ttatcaacgg taaggttgcc cgtgactcta aagtccgtgt tatccgtgat ggtgtcgtta
    11101 tctatgatgg tgaactcgca agcttgaaac actataaaga cgacgttaag gaagttacaa
    11161 acggccgtga aggtggattg atgatcgacg gctacaatga tattaagatg gatgatgtga
    11221 ttgaggcgta tgtcatggaa gaaatcaaga gataagattt tttgctcctt tcttaggtgg
    11281 tgagggacgc aagcaaaccg atggtttcat tgcttatttt tgagcctagg gtctcaaaaa
    11341 tcccctgtga tgggactgat aaatcagttc catcactttc accacggcga aagaagcaga
    11401 tgacttcaaa ttgaacttcg tttcaattta aactgaaaat caagaagttt aaaatagcta
    11461 ggtctgctgg cctagctttt ggttcaaagt agagaaagga atatcatggc aaatcatttc
    11521 cgtacggatc gtgtgggcat ggaaatcaag cgtgaagtca atgagatttt gcaaaagaaa
    11581 gtccgtgatc cacgtgtcca aggtgtgacc atcacagatg ttcagatgct gggtgacttg
    11641 tctgttgcca aggtttatta caccattttg agtaaccttg cttcggataa ccaaaaagcc
    11701 caaatcgggc ttgaaaaagc aactggtacc atcaaacgtg aacttggtcg caatttgaaa
    11761 ttgtacaaaa tcccagattt gaccttcgtc aaagacgagt ccatcgagta tggaaacaag
    11821 attgacgaga tgctacgcaa tctggataag aactaaagaa gaggggttgc ccctcttttt
    11881 tggtggagga aaataggttg aatttgaaat ggaaaaatat tcttttataa tagattgaaa
    11941 ctagaatagt ac
//
LOCUS       DAVMCN010000049        11875 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVMCN010000049 DAVMCN010000000
VERSION     DAVMCN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.050"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            249..902
                     /locus_tag="VYP85_001625"
     CDS             249..902
                     /locus_tag="VYP85_001625"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1882108.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            912..1376
                     /locus_tag="VYP85_001626"
     CDS             912..1376
                     /locus_tag="VYP85_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1882109.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPELDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1389..2657
                     /locus_tag="VYP85_001627"
     CDS             1389..2657
                     /locus_tag="VYP85_001627"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1882110.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2671..2931
                     /locus_tag="VYP85_001628"
     CDS             2671..2931
                     /locus_tag="VYP85_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882111.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2942..4303
                     /gene="pdrM"
                     /locus_tag="VYP85_001629"
     CDS             2942..4303
                     /gene="pdrM"
                     /locus_tag="VYP85_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1882112.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4457..5425
                     /locus_tag="VYP85_001630"
     CDS             4457..5425
                     /locus_tag="VYP85_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1882113.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5441..6433
                     /locus_tag="VYP85_001631"
     CDS             5441..6433
                     /locus_tag="VYP85_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1882114.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6651..7694
                     /locus_tag="VYP85_001632"
     CDS             6651..7694
                     /locus_tag="VYP85_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1882115.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGIQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7758..9443
                     /gene="lpdA"
                     /locus_tag="VYP85_001633"
     CDS             7758..9443
                     /gene="lpdA"
                     /locus_tag="VYP85_001633"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1882116.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9507..10496
                     /locus_tag="VYP85_001634"
     CDS             9507..10496
                     /locus_tag="VYP85_001634"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1882117.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10563..11633)
                     /gene="xerS"
                     /locus_tag="VYP85_001635"
     CDS             complement(10563..11633)
                     /gene="xerS"
                     /locus_tag="VYP85_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1882118.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3547 a         2213 c         2656 g         3459 t
ORIGIN      
        1 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
       61 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
      121 ttataaactg tattcacgta ttcaaatcgt atatagtcga tttattaaat ctttagataa
      181 actgtaaaaa gtggtttcca tagccacttt ttgctataat agaggcagta aaaatgaagg
      241 agtcggctat ggaacactcg tcttggcatg ctttgattaa ggcgcaatta cctgagggtt
      301 atttcgggaa aatcaatcag tttatggagc aggtctattc tcaggggatt atttatccac
      361 ccaaggaaaa ggtttttcag gctctcttga caacactgct tgaagaagtt aaggtggtaa
      421 ttctagggca agacccctat cacggaccag gtcaagcgca gggcttgagt ttttccgtac
      481 ctgactctat cccagctcca ccatccttgc aaaatatctt gaaagaattg tcagatgata
      541 tcggagttaa gaaatctcat gatttgacag cttgggctga gcaaggagtc ttgcttctta
      601 atgcttgttt gactgttcct gctggacagg ccaatggtca tgctggtcaa atctgggagc
      661 cttttactga tgctgtgatt caggtggtca atcatctaga tagaccagtc gtttttgtac
      721 tctggggagc ttatgcacgt aagaagaagg ccttagttac caatcctcat cacttgatta
      781 ttgaatcagc ccatccaagt cctttgtcgg tttatagagg attttggggt tccaagcctt
      841 tttccaaggc caatacattc ttaaaagaga caggacaaga gccaatcgat tggcttagat
      901 aaggagaaaa tatgcctcag ttagcgacga tttgttacat tgataatggg aaagaactgc
      961 tcatgctcca tcgtaataag aaacccaatg atgtccatga agggaaatgg attggtgtgg
     1021 gtggtaagct agagagagga gagacgcccc aggaatgcgc ggtacgtgaa atccttgaag
     1081 aaacagggct caaagccaag ccagttctaa aaggtgtcat cacttttcct gaatttacac
     1141 cagaattaga ctggtacacc tatgttttta aggtgacgga gtttgagggc gacttgattg
     1201 actgcaatga ggggatgcta gaatgggttc cctatgatga ggttttgagc aagccgactt
     1261 gggaaggtga ccacaccttt gttgagtggc ttttagagga taaacccttc ttttcagcca
     1321 agtttgttta tgatggggat aaattgttgg atacccaagt tgatttctat gaataaagga
     1381 gaaagcagat gctactaatc aaaaatggtc gtgtaatgga tcccaagtct ggtttggatc
     1441 aagtttgtga tgtcttagtt caagatggga aaattatcaa aattgcgcct gagatcacgg
     1501 aagaaggagc agaaacgatt gatgctactg gtcatgtggt tgctcctggt ttggtcgata
     1561 ttcatgtgca tttccgtgaa cctggtcaaa cacataaaga agacattcat actggtgccc
     1621 tagcagccgc tgcaggtggt tttactactg tcgtcatgat ggctaatacc agtccaacca
     1681 tttcagacgt ggagactttg caagcagttc tccagtcagc tgccaaagag aagattaatg
     1741 tcaagacagt tgcgaccatt actaaaaact ttaatggtaa aaacttgact gactttaagg
     1801 cacttttaga agctggtgcg gttggtttct ctgatgacgg tattccgctt gagagcagta
     1861 agattgtcaa ggaagccatg gaggaagcca aaaaactcaa tacctttatc agccttcatg
     1921 aggaagatcc aggtttgaac ggtgttcttg gctttaatga aaatattgct agagaacatt
     1981 tccatatctg tggtgctact ggggtggctg agtacgctat gatggcgcgt gatgtcatga
     2041 ttgcctatgc aactaaagcc catgttcaca tccagcattt gtctaaggaa gaaagtgtta
     2101 aagtagtgga gtttgctcag gggttaggtg cagaagtcac agcagaagta gcaccacagc
     2161 atttctctaa gacagaagca cttcttttaa cacaaggtag caatgctaag atgaatccac
     2221 cgcttcgttt ggaatcagac cgtcgtgccg ttatcgaagg tctcaaatca ggtgtcatca
     2281 cagttattgc gactgaccac gcgcctcatc atgtagatga aaaaaatgtt gaagatatta
     2341 ccaaagtgcc atctggtatg actggcttag aaacatccct gtctctcggc ttgacctatt
     2401 tggtagaagc tggtgagttg agcttgatgg aattacttga aaaaatgaca tacaacccag
     2461 ccaagcttta caactttaaa gcaggttact tggctgagaa tggtccagca gatatcacta
     2521 tttttgatgc caaggctgac cgccttgtgg actcccattt tgcttccaaa gcagctaatt
     2581 caccattcat cggtgaaacc ttaaaagggc aggttaaata taccatctgt aagggacaaa
     2641 tcgtctatca agcttgatag gagttagaat atgaattatt ttcgaaaacg tagggagaga
     2701 caagcgaaat ctaatagtgg aatttactgt cccgcagcta atcgttccaa aattcaatat
     2761 gaaactaaag aaaaagctga ccatgcggtt caatatgata acggaggttt agttagaagc
     2821 tattattgtc gtacatgtgc gtgttggcat actacttcaa aatctaataa acctccgcta
     2881 agtttgaaaa actatggtct gaaactcttt ggtttagata aatcagaata gaaagagaag
     2941 tatgtataag acaaagtgtt tacgagagaa gttagtatta tttttaaaaa ttttcttccc
     3001 aatcctgatc taccaatttg ccaattattc tgcctctttt gttgatactg caatgacagg
     3061 tcaatacaac actatggact tggctggtgt atctatggca accagtatct ggaatccttt
     3121 ctttacattt ctaacaggga ttgtgtcagc cttggtgcct atcattggtc accatcttgg
     3181 tcgaggcaaa aaggaagaag ttgcgtctga tttttaccaa tttatttatt tggccttggg
     3241 cctatctgtg gtcttgctgg ggatggtact tttcttggca ccaacaatct tgaatcatat
     3301 tgggttagaa gcagcagtag cggcagtagc ggttcgctat ctttggtttt tatctatcgg
     3361 gattatcccc ttgttgctct ttagcgtcat tcgttccttg ctggattcgc tgggcttgac
     3421 caaactgtcc atgtacctca tgcttttgtt actccctctc aatagcggat ttaactatct
     3481 cttgatttac ggtgcctttg gtgttccaga actgggaggg gctggtgctg gtttaggaac
     3541 atccttggcc tactgggtct tgcttgggat ttctgttctg gttttattta aacaggagaa
     3601 gctcaaagcc ttacaccttg agaaacgaat tccacttaat atggataaca ttaaggaagg
     3661 agttcgttta ggtctgccta ttgggggaac tgtcttcgcg gaagtggcta tcttttcagt
     3721 ggttggcttg attatggcta agttttcgtc cttgattata gctagtcacc agtcagctat
     3781 gaacttttca agtcttatgt acgcctttcc tatgagtatc tcatcggcta tggctattgt
     3841 cgtttcctat gaagtgggag ccaagcgatt tgatgatgcg aaaacctata ttggtctagg
     3901 aagatggact gctctcattt ttgcggcctt caccctaacc ttcctttaca tttttagggg
     3961 aaatgtggcc agtctttatg gtaacgaccc aaaatttatc gatttgacag cgcgtttttt
     4021 aacttatagt cttttcttcc agttagcaga tacctttgcg gcaccgcttc agggaatttt
     4081 gcgggggtat aaggatacag ttattccttt ttaccttggt ttgcttggtt attggggcgt
     4141 agcaatccct gtggctacgc tatttgattc cctaacagat tttggagctt attcttactg
     4201 gatcggcttg attattagtt tgattgtgag tggggcgctc taccgttggc gtttaactgt
     4261 gattatgaag agatttgaat ctttagcaaa atccaaacgc taaaaagttt gtgaaaaaat
     4321 atccttgaca agaaaatccc ttgttttcac ggggttttct tttttatttt gtgaaatttc
     4381 ttttagaaaa actttgacag tatttgccaa aaacggtaaa atagtaaggt aagaagaaag
     4441 ttagaaaggc aagaagatgt caactttaga taaaaatctt ttgctagaaa tgttccgtaa
     4501 gatggaagaa atccgtcgca tggacttaaa aattgcacaa ttagtaaaga aagggaaagt
     4561 gccaggaatg acgcactttt ctgttggtga agaggcagct aacgtggggg ctatgttagc
     4621 tctcaatcca gatgatctga ttacctcaaa ccaccgtgga cacgggcaag ctattgctaa
     4681 agggattgac ctcaacggaa tgatggctga aatccttggt aaatacactg gaacctgtaa
     4741 agggaaaggt ggatctatgc atatcgctga ccttgatgct gggaaccttg gtgccaatgg
     4801 tatcgtaggt ggtggtatgg ggatcgctgt cggtgcagcc ctcagtcagc aaatgcaaaa
     4861 taccggtaaa atcgttgttt gcttctttgg agatggtgcg accaatgaag gtgttttcca
     4921 cgaagcagtg aacatggctt ctatctggaa cctgccagtc attttctatt gcattaacaa
     4981 cggttacggt atctctgcgg atatcaagaa aatgaccaat atagaacata tccatcaacg
     5041 tagcgccgct tatggaattc ctggaatgtt catcgaagac ggtaacaatg tcatcgatgt
     5101 ctatgaagga tttcagaaag ctgtagacca tgttcgcagt ggcaatggtc cagtcttgat
     5161 tgaaagtgta acttatcgct ggctcggtca ctcatcatct gaccctggta aatatcgtac
     5221 gcgtgaagaa gtggaattgt ggaaacaaaa agatccaatc gaaaacctcc gcaattacct
     5281 tattgaaaat aacattgcaa gtgccgaaga attggaagaa atccaagcgc aagtaaagga
     5341 agcagtagaa gcttctgtta aatttgcaga ggaaagccca ttcccaccgc ttgaatcagc
     5401 ctttgaagat atttacgcag actaaggaga aagagataaa atggaaacaa aaacaatgtc
     5461 cttccgtgac accattatcc ttgctatgtc tgaggaaatg cgtcgcgatg aaaatgtgtt
     5521 cttgatggga gaagacgtcg gtgtcttcgg aggagacttc ggtacttctg ttggaatgct
     5581 tgaagaattt ggtccagaac gcgtccgtga ctgtccgatt tctgaagctg ccatctctgg
     5641 agcagcagca ggagcagcca tgacaggact tcgtccaatc gtcgatatga ccttcatgga
     5701 cttctctgtt attgccatgg acaatatcgt caaccaagct gctaaaacac gttacatgtt
     5761 tggtggtaaa ggtcaggttc caatgactgt tcgttgtgca gctggtaacg gagttggctc
     5821 tgccgcccag cactcacaat ctctagagtc ttggtttact cacattccag gacttaaggt
     5881 tgtggcacct ggaacacctg cggacatgaa aggcctgctt aagtcttcta tccgtgataa
     5941 aaacccagtt attatacttg agtacaagtc agaatttaac caaaaagggg aagtgccagt
     6001 tgatccagac tacacaattc cacttggggt tggtgaaatc aaacgccaag gaacggatgt
     6061 aacagttgtt acttatggaa aaatgcttcg ccgtgtggtt caagctgctg aagaattagc
     6121 agaagaagga atttcagttg aaattgttga cccacgtacc cttgttccgc ttgataagga
     6181 tatcatcata aactcagtga agaagactgg taaggttgtt ctggtcaacg atgcccacaa
     6241 aacaagtggc tatatcggtg aaatttcagc tattatttca gaatcagaag catttgacta
     6301 tctagatgca ccaatccgcc gttgtgcagg agaagatgtg ccgatgcctt atgcacaaaa
     6361 cctagaaaat gcaatgattc caacagttga aagtatcaaa gatgcaatcc gaaaaactta
     6421 taacaaagaa tagagttaca taagataagt tatgtaaata aaataaagct gacgagaaac
     6481 tttgtatctt ttaggtgcag agctcttcgt cattaatatc ttagattaga gcacgggcta
     6541 aaagctcgga aaaaagataa atctccttgg cttcatcgaa gccatcgtcg atttcctatt
     6601 tttcagtcgc ttttgacgcc ctttgtatca taaatagaat tggagaggtc atggctgatg
     6661 acaagctaag agcgactcct gcagctagaa agttagcgga tgatttaggg ataaacctct
     6721 acgacgtttc tggctcaggt gcaaacggtc gtgtccacaa agaagacgtg gaaacttata
     6781 aagacacaaa cgtggttcgc atttcgccac ttgcaaaacg aattgccctc gaacataaca
     6841 ttgcttggca ggaaatccaa ggaaccggtc atcgtggtaa aatcatgaag aaggatgttt
     6901 tggccctgct tcctgaaaat atcgaaaacg atagcatcaa atctcctgct cagattgaaa
     6961 aagtggaaga agttcctgat aacgtaacac catatggtga aatcgagcgt attccaatga
     7021 caccaatgcg taaggttatt gcccaacgca tggttgaatc ttacttgact gcgccaacct
     7081 tcaccctcaa ctatgaagtt gatatgactg aaatgttggc tcttcgtaag agggttcttg
     7141 agccaatcat ggaagcaact gggaagaaga ctactgtaac agaccttctt tcacttgcag
     7201 ttgttaagac tcttatgaaa catccataca tcaacgcttc attgacagaa gatggcaaga
     7261 ctattatcac tcacaactat gtcaatcttg ctatggcagt tgggatggat aatggattga
     7321 tgacacctgt tgtttacaat gctgagaaga tgagtctttc agaactggtt gtagccttta
     7381 aggatgttat tggccgtacc ttggatggta aattggctcc aagtgagtta caaaattcaa
     7441 cattcacaat cagtaatttg ggaatgtttg gtattcagtc ctttggtccg attattaacc
     7501 aacccaactc agctatcctt ggtgtcagtt cgacaatcga gaagccagtt gtcgtcaatg
     7561 gtgaaattgt gattcgccca atcatgagtt taggattaac cattgaccac cgtgtcgtag
     7621 atggtatggc tggtgctaag tttatgaagg acttgaaaga gttgattgaa accccaatct
     7681 caatgttgat ttaagagcaa gagtattcat ttttaagata tagataaagg aaggaagaca
     7741 tggccttaga aataattatg ccaaaagccg gcgtggatat gacagaagga caaatcgtcc
     7801 aatggaataa aaaagtcgga gaatttgtaa aagaaggaga aatccttttg gaaatcatga
     7861 ctgataaagt cagcatggaa ttggaagccg aagaagatgg gtacttgatt gccattctca
     7921 aaggagatgg tgaaactgtc cctgtaacgg aagttatcgg ttaccttggt gaagaaaggg
     7981 aaaacatccc aacagctgga gcagcatcgc cagaagctag ccctgtacct gtagcaagta
     8041 cctcaaacga tgatggtaag agcgatgatg cttttgatat cgttgtgatt ggtggaggtc
     8101 ctgctggtta tgttgcagcc attaaagctg cccaactcgg cggtaaggtt gcccttgttg
     8161 agaaatctga acttggtgga acctgcttaa accgtggatg tattccaacc aagacctacc
     8221 ttcataacgc tgaaattatt gaaaatatcg gtcatgctgc aaatcgtggt atcgtgattg
     8281 aaaatcctaa cttcactgtt gatatggaaa aacttttaga aactaaatct aaagttgtta
     8341 atactcttgt tggtggtgtt gcaggacttc ttcgtagcta cggagttact gttcataaag
     8401 gaattggtac aatcactaaa gacaagaacg tcttggtaaa tggctctgaa ttgcttgaaa
     8461 ccaagaaaat cattcttgct ggtggttcaa aagtcagcaa gatcaatgtc cctggtatgg
     8521 aatctccact tgtcatgact agtgatgaca ttcttgaaat gaacgaagtg ccagaaagcc
     8581 ttgttatcat cggtggtgga gttgtcggta tcgaactcgg tcaggccttc atgacatttg
     8641 gttcaaaagt gactgttatc gaaatgatgg accgtatagt tccagctatg gatgcggaag
     8701 tttctaagaa ccttcgcttg atccttgagc gtaaaggaat gaccatcttg actggtacta
     8761 aactgcaaga aatcattgag gaaaatggtc aacttcgtat caaggttgaa ggaaaagacg
     8821 atatcatcgc aagcaaagct cttctttcaa ttggtcgtat gccagacctt gaaggtattg
     8881 gagaggttga gtttgaattg gatcgtggtt gtatcaaggt caatgaatac atggaaactt
     8941 cagttccagg catttatgca ccaggtgaca tcaacggtac taagatgttg gctcacgcag
     9001 ctttccgcat gggtgaagtt tccgctgaaa atgcccttaa aggaaatcat gcagttgcca
     9061 aattgaattt gactcctgca gccatctaca ctctccctga agtagcagca gtaggtttga
     9121 cagaagaaca agcccgtgag aaatacgatg ttgccatcgg taagtttaac tttgctgcta
     9181 acggtcgtgc tattgcatct gacgcagctc aaggtttcgt aaaagttatc gctgataaga
     9241 aatacggaga aatccttggt gtacacatta ttggtcctgc agccgcagaa ttaataaacg
     9301 aagcatcaag catcatcgaa atggaaatca ctgttgagga aatgctgaag accatccacg
     9361 ggcacccaac ttactctgaa gtgatgtacg aagcgtttgc agatgttcta ggaatggcca
     9421 tccattcacc taagaaaaaa taaaacgaag atagattaga ctggaaggtt atttccagtc
     9481 tctatcatat aaagtaaagg gatatcatga aatacattat caatcattca aatgacactg
     9541 cttttaatat tgccttggaa gaatacgcct ttaaacacct tttggatgag gatcaaatct
     9601 tcctactttg gattaacaag ccatctatca ttgttggtcg tcaccagaac actatcgaag
     9661 aaatcaaccg tgattatgtt cgcgaaaatg gtattgaggt agttcgccgt attagtggtg
     9721 gtggagctgt ttaccacgat ttaaataacc tcaactacac gatcatctcc aaagaagatg
     9781 aaaataaggc atttgacttc aagagcttct caactccggt tatcaatacc ctggctcaac
     9841 ttggggttaa agctgagttc acaggtcgta atgaccttga gattgatggt aagaagttct
     9901 gtggcaatgc ccaagcctat atcaacggcc gtatcatgca ccacggttgc ttgctctttg
     9961 acgttgattt gtcagtcctc gcaaatgccc ttaaggtttc aaaagataaa tttgaatcaa
    10021 aaggtgtgaa atccgtccgt gcccgtgtaa ccaatattat caatgaatta ccaaaaaaaa
    10081 tcacagtcga aaaattccgt gatttactcc tggaatacat gaaaaaagag tacccagaga
    10141 tgactgaata cgtcttttca gaagaagaat tggccgaaat caatcacatc aaggatacta
    10201 agtttggaac ttgggactgg aactatggta aatcacctga atttaacgtc cgtcgtggaa
    10261 ccaaattcac tagtggtaag gttgaagtct ttgctaacgt tactgaatca aaaatccaag
    10321 acatcaagat ttatggtgac ttctttggta ttgaagacgt tgctgcagta gaagatgtcc
    10381 ttcgtggggt gaaatacgaa cgcgaagatg ttcttaaggc gctaaaaacc attgatatca
    10441 cacgctactt cgctggtatt agccgtgaag aaatcgctga agcggtagtt ggataaatca
    10501 aaaaaagaag ttggccaact tctttttttg atatttattt acataattta aaatacgtaa
    10561 aatcataaac tatctagagc attcttttgt tcatcattaa caatatgggt atagaggtca
    10621 gtgacttgtg tgctggcatg tcctagttgg tgactgacta aaacttgtga tttagtcgca
    10681 tcatagagcc tagttgctag cgtatggcgc agtttatggg gtgttacacg cactttaaaa
    10741 tcctctgagt atttagcaac cattttctca acgctagaag catcgatacg attaggaaca
    10801 cctctgtaga gagttaaaaa aagggctgta tctgtttttt ccgttttata gcgttgattc
    10861 cgaatggcca gataattctc taaataaggt ttagcaaaag cagcgacatt gactgagtca
    10921 cgtttgccac cttttcgagt aacatcaata accatcattt ttagattgag atctcttaga
    10981 tctagattaa cagcttcaga taagcgaaca ccagatgcca agagaagggc aataatggct
    11041 aaatctcgtt ctttattttt gttgaatgat gagagagctc gatttgaaag ctgttgtggg
    11101 tgctcttgat cgatataagt tagaaaacct tctgtttcat cacctagaaa gagtttttgc
    11161 ttgatatttt cagctctggc agcaagggtt tctttctttt tcttggttga aacttttttc
    11221 attacattac gatagaaata aggttccccc tgatcgtttt caacctcctc ggttagatac
    11281 ttgtaaagac tagaaagtgc tgataaggtt cgattgatag ttgtctgtga aacaccttgt
    11341 tttgttgtat tagcattcag caagggacgt tcacgtagat aaaggataaa ggattccatg
    11401 tctttcttag acatattttc caaaactgat aaaggaatat cggatatttt atcagcgttt
    11461 gaaataccag actccaaaac ccagctgaaa aatcggtcat attccttaag gtattcgtac
    11521 agggttgtaa aactgtaggg cacagccagc ttagattggt agtattccag aacataccag
    11581 ggcatgagtt gttttagttt gtcgattcgt tccagtaaaa tctcacgttt catgtatttt
    11641 ctccataagt aagtatacta gtagtatagc atagacttgt atatttttca agaaaattat
    11701 agtttttctg aaagatgtta taggagtttt tcaaagtgat aaaaagactt agacctacaa
    11761 acaaaacaga ataaggaaaa taataaaaat ctcacccact aaacttctgt taatactaca
    11821 taactgaaga gctatataag gagctatgag atacaaaaca cattgtataa tagat
//
LOCUS       DAVMCN010000050        11634 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVMCN010000050 DAVMCN010000000
VERSION     DAVMCN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.051"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(151..1782)
                     /locus_tag="VYP85_001636"
     CDS             complement(151..1782)
                     /locus_tag="VYP85_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1882119.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGFGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2075..7015
                     /locus_tag="VYP85_001637"
     CDS             2075..7015
                     /locus_tag="VYP85_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1882120.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANPELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDNLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7105..8301
                     /locus_tag="VYP85_001638"
     CDS             7105..8301
                     /locus_tag="VYP85_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1882121.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8437..8964
                     /locus_tag="VYP85_001639"
     CDS             8437..8964
                     /locus_tag="VYP85_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1882122.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9041..9397
                     /gene="glnR"
                     /locus_tag="VYP85_001640"
     CDS             9041..9397
                     /gene="glnR"
                     /locus_tag="VYP85_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1882123.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9434..10780
                     /gene="glnA"
                     /locus_tag="VYP85_001641"
     CDS             9434..10780
                     /gene="glnA"
                     /locus_tag="VYP85_001641"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1882124.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10876..10995)
                     /locus_tag="VYP85_001642"
     CDS             complement(10876..10995)
                     /locus_tag="VYP85_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1882125.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11484..11634
                     /locus_tag="VYP85_001643"
                     /pseudo
     CDS             11484..11634
                     /locus_tag="VYP85_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3722 a         2130 c         2522 g         3260 t
ORIGIN      
        1 gatttctaac aatgttttag aaatagaggt gtactattct agtttcaata tactatatat
       61 ctgcagaata ctctttcagt ttcattcagc ctagtcttgc ttaggaaaaa gtaaaaagcc
      121 atccaattat gatggatagc ttcttggttc ttagatttgt tctgcaaaaa ccttttcagc
      181 aaggttcata gcgtggtctg atacacgagt gtagtgtgag atgatgtcga taaagttgac
      241 cccagcttgt gttgaacatt cgcctttgtt gaggcgtttg atgtgggttt ttctgagaac
      301 acgttctatc ttattgattg cttcatgacg ttctacaaga ctgcgtgctt tttcaatatc
      361 attgttttcc acactatcca gagcatcttt gataaagtca ctagtttggc ggtaaacttc
      421 ctctaattct ttcaaggcgg catcagaaaa ttcaacattt ttccgttgaa gatagtcagt
      481 cagattgagt agagcctccg tgtggtctcc aatccgttcc aaatcacggg aggaatcaag
      541 gatattggta agcacttcac tttctttttg gctgagagct tcgcttgaaa gggcaatgag
      601 ataacgtgtt aattgctcat cgatggtgtt aattgcttct tcggttttat gccctttttc
      661 agcaactttt tcatccaaat caatgatgta cttataggaa aggtcaaagg ctttagcagc
      721 gtagtttcct aagtgcaaga gctctttctt agcatttcct agagcgatag atggggcctg
      781 tttgatgaaa tgttcatcaa gatataaggg ttcgtatttg acaacctcgt cctctccagg
      841 aataatcttg gttacaaagt aagccagagc tccgataaat ggaaattgga caatggtgtt
      901 ggtaatatta aaggttccgt gagcaaaggc gatggtcatt tccggtgcta gatttagcgt
      961 agcttcaaac caatgaatca ggacagtaaa aggaactaga aaaataacgc agacgactgt
     1021 tccgataacg ttgaaggcaa catgagctcc tgctacccgt ttagctgcaa tattagcccc
     1081 taaagaggca atgatggctg taatggttgt cccgatattg tcaccaaata gaactggcaa
     1141 agctccctgt aggtcaatta gattgccggc gtagaggttt tgtaaaatcc caatggtagc
     1201 cgaagaagct tgaattagca aggtcaagcc ggtaccgaca aagacaccca aaacaggatt
     1261 cttacttagc tcaatcatat agtccttaaa gacctgtaaa tccttgagtg gagccattgc
     1321 gccgctcatg agattgaggg caaaaaagat accaccgaaa ccaaagagga tgcgtccgat
     1381 attattgact gtccgatttt ttgtaaaaaa gagacagacg gcaccgataa agagcatagg
     1441 tagggcatag ttacctaatt taaaaccgat gagaaaggat gtgacagttg tcccaatatt
     1501 agcacccatg acaatcccga tagcctgacg taaggttaag agaccggcac tgaccaggcc
     1561 gactgtgata actgttacac cagaactaga ctgaattaga gcagtcatcc caataccaac
     1621 cagaactcca aagaaaggat tactagtata tttgtcaatg taaaaacgaa ggcgatctcc
     1681 agcagcttgt tgcaaaccgt ctcccatggt cttgatgcta tataagaata gccccagacc
     1741 acctaaaaag tgaaataaaa tttcctgcca attaatggac atttcttttt cctccgaaaa
     1801 ataatcgcgg aatatctcct attctatttt aaaggataaa agtaaatcta acaagtgtta
     1861 atgtcaagtt tgtaaaagaa aattataatt gataagtgta ttatttttaa gagtttttaa
     1921 ccttatttta gatttgtgca aacagttatt gttttttgtc taaaaatgtt ttaggataaa
     1981 aatgtgatta tcatggttct agagtttgat aaaaaactac agaatataaa gcgctttctt
     2041 gaaaacaaca aaatcaatct tttaggagga gaaaatgaag aatccatttt ttgaaagacg
     2101 ttgtcgttac agtattcgta agttatcagt aggagcctgc tcgctgatga ttggtgctgt
     2161 tttatttgct ggtccagcct tggctgaaga aactgcagtt cctgaaaata gcggagctaa
     2221 tccagagctt gtttcaggag agagtgagca ttcgaccaat gaagctgata agcagaatga
     2281 aggggaacat gctagagaaa acaagctaga aaaggcagaa ggagtagcga tagcatctga
     2341 aactgcagaa gcagctagcg cagctaaacc agaggaaaaa gcaagtgagg tggttgcaga
     2401 aacaccatct gcagaagcaa aacctaagtc tgacaaggaa acagaagcaa agcccgaagc
     2461 aactaaccaa ggggatgagt ctaaaccagc agcagaagct aataagactg aaaaagaagt
     2521 ccagccagat gtccctaaaa atacagaaaa aacattaaaa ccaaaggaaa tcaaatttaa
     2581 ttcttgggaa gaattgttaa aatgggaacc aggtgctcgt gaagatgatg ctattaaccg
     2641 cggatctgtt gtcctcgctt cacgtcggac aggtcattta gtcaatgaaa aagctagcaa
     2701 ggaagcaaaa gttcaagcct tatcaaacac caattctaaa gcaaaagacc atgcttctgt
     2761 tggtggagaa gagttcaagg cctatgcttt tgactattgg caatatctag attcaatggt
     2821 cttctgggaa ggtctcgtac caactcctga cgttattgat gcaggtcacc gtaacggggt
     2881 tcctgtatac ggtacactct tcttcaactg gtctaatagt attgcagatc aagaaagatt
     2941 tgctgaagct ttgaagcaag acgcagatgg tagcttccca attgcccgta aattggtaga
     3001 catggccaag tattatggct atgatggcta tttcatcaac caagaaacaa ctggagattt
     3061 ggttaaacct cttggagaaa agatgcgcca gtttatgctc tatagcaagg aatatgctgc
     3121 taaggtaaac catccaatca agtattcttg gtacgatgcc atgacctata actatggacg
     3181 ttatcatcaa gatggtttgg gagaatacaa ctaccaattc atgcaaccag aaggagataa
     3241 ggttccggca gataacttct ttgctaactt taactgggat aaggctaaaa atgattacac
     3301 tattgcaact gccaactgga ttggtcgtaa tccttatgat gtatttgcag gtttggaatt
     3361 gcaacagggt ggttcctaca agacaaaggt taagtggaat gacattttag acgaaaatgg
     3421 gaaattgcgc ctttctcttg gtttatttgc cccagatacc attacaagtt taggaaaaac
     3481 tggtgaagat tatcataaaa atgaagatat cttctttaca ggttatcaag gagaccctac
     3541 tggccaaaaa ccaggtgaca aagattggta tggtattgct aacctagttg cggaccgtac
     3601 gccagcggta ggtaatactt ttactacttc ttttaataca ggtcatggta aaaaatggtt
     3661 cgtagatggt aaggtttcta aggattctga gtggaattat cgttcagtat caggtgttct
     3721 tccaacatgg cgctggtggc agacttcaac aggggaaaaa cttcgtgcag aatatgattt
     3781 tacagatgcc tataatggcg gaaattccct taaattctct ggtgatgtag ccggtaagac
     3841 agatcaggat gtgagacttt attctactaa gttagaagta actgagaaga ccaaacttcg
     3901 tgttgcccac aagggaggaa aaggttctaa agtttatatg gcattctcta caactccaga
     3961 ctacaaattc gatgatgcag atgcatggaa agagctaacc ctttctgaca actggacaaa
     4021 tgaagaattt gctctcagct cactagcagg taaaaccatc tatgcagtca aactattttt
     4081 tgagcatgaa ggtgctgtaa aagattatca gttcaacctc ggacaattaa ctatctcgga
     4141 caatcaccaa gagccacaat cgccgacaag cttttctgta gtgaaacaat ctcttaaaaa
     4201 tgcccaagaa gcggaagcag ttgtgcaatt taaaggcaac aaggatgcag atttctatga
     4261 agtttatgaa aaagatggag acagctggaa attactaact ggctcatctt ctacaactat
     4321 ttatctacca aaagttagcc gctcagcaag tgctcagggt acaactcaag aactgaaggt
     4381 tgtagcagtc ggtaaaaatg gagttcgttc agaagctgca accacaacct ttgattgggg
     4441 tatgactgta aaagatacca gcctaccaaa accactagct gaaaatatcg ttccaggtgc
     4501 aacagttatt gatagtactt tccctaagac tgaaggtgga gaaggtattg aaggtatgtt
     4561 gaacggtacc attactagct tgtcagataa atggtcttca gctcagttga gtggtagtgt
     4621 ggatattcgt ttgaccaagc cacgtactgt tgttagatgg gtcatggatc atgcaggagc
     4681 tggtggtgag tctgttaacg atggcttgat gaacactaaa gactttgacc tttattataa
     4741 agatgcagat ggtgagtgga agctagctaa ggaagtccgt ggtaacaaag cacacgtgac
     4801 agatatcact cttgataaac caatcactgc tcaagactgg cgcttgaatg ttgtcacttc
     4861 tgacaatgga actccatgga aggctattcg tatctataac tggaaaatgt atgaaaagct
     4921 tgatactgag agtgtcaata ttccgatggc caaggctgca gcccgttctc taggcaataa
     4981 caaggtacaa gttggctttg cagatgtacc ggctggagca actattaccg tttatgataa
     5041 tccaaattct caaactccgc tcgcaacctt gaagagcgaa gttggaggag acctagcaag
     5101 tgcaccattg gatttgacaa atcaatctgg tcttctttat tatcgtaccc agttgccagg
     5161 caaggaaatt agtaatgtcc tagcagtttc cgttccaaaa gatgacagaa gaatcaagtc
     5221 agtcagccta gaaacaggac ctaagaaaac aagctacgcc gaaggggagg atttggacct
     5281 tagaggtggt gttcttcgag ttcagtatga aggaggaact gaggacgaac tcattcgcct
     5341 aactcacgca ggtgtatcag tatcaggttt tgatacgcat cataagggag aacagaatct
     5401 tactctccaa tatttgggac aaccagtaaa tgctaatttg tcagtgactg tcactggcca
     5461 agatgaagca agtccgaaaa ctattttggg aattgaagta agtcaggaac cgaaaaaaga
     5521 ttacctagtt ggtgataact tagacttgtc tgaaggacgc tttgcagtgg cttatagcaa
     5581 tgacaccatg gaagaacatt cctttactga tgagggagtt gaaatttctg gttacgatgc
     5641 tcaaaagact ggtcgtcaaa ccttgacgct tcgttaccaa ggtcatgaag tcaactttga
     5701 tgttttggta tctccaaaag cagcattgaa cgatgagtac ctcaaacaaa aattagcaga
     5761 agttgaagct gctaagaaca aggtggtcta taactttgct tcaccagaag taaaagaagc
     5821 cttcttgaaa gcaattgaag cggccgaaca agtgttgaaa gaccatgaaa ctagcaccca
     5881 agatcaagtc aatgaccgac ttaataaatt gacagaagct cataaagctc tgaatggtca
     5941 agagaaattt acggaagaaa agacagagct tgatcgctta acaggtgagg ctcaagaact
     6001 cttggctgcc aaaccaaacc atccttcagg ttctgcccta gctccgcttc ttgagaaaaa
     6061 caaggccttg gttgaaaaag tagatttgag tccagaagag cttgcaacag cgaaacagag
     6121 tctaaaagat ctggttgctt tattgaaaga agacaagtca gcagtctttt ctgatagtaa
     6181 aacaggtgtt gaagtacact tctcaaataa agagaagact gtcatcaagg gtttgaaagt
     6241 agagcgtgtt caagcaagtg ctgaagagaa gaaatacttt gctggagaag atgctcatgt
     6301 ctttgaaata gaaggtttgg atgaaaaagg tcaagatgtt gatctctctt atgcttctat
     6361 tgtgaaaatc ccaattgaaa aagataagaa agttaagaaa gtatttttct tacctgaagg
     6421 caaagaggca gtagaattgg cttttgaaca aacggatagt catgttatct ttacagcacc
     6481 tcactttact cattatgcct ttgtttatga atctgctgaa aaaccacaac ctgctaaacc
     6541 agcaccacaa aacaaagtcc ttccaaaacc tacttatcaa ccggcttctg atcaacaaaa
     6601 ggctcctaaa ttggaagttc aagaggaaaa ggttgccttt catcgtcaag agcatgaaaa
     6661 tgctgagatg ctagttgggg aacaacgagt cattatacag ggacgagatg gactgttaag
     6721 acatgtcttt gaagttgatg aaaacggtca gcgtcgtctt cgttcaacag aagtcatcca
     6781 agaagcgatt ccagaaattg ttgaaattgg aacaaaagta aaaacagtac cagcagtagt
     6841 agctacacag gaaaaaccag ctcaaaatac agcagttaaa tcagaagaag caagcaaaca
     6901 attgccaaat acaggaacag ctgatgctaa tgaagcccta atagcaggct tagccagcct
     6961 cggtcttgct agtttagcct tgaccttgag acggaaaaga gaagataaag attaaatatc
     7021 gaaaaatctt gtgaaatctt tccttatatt tccaaagtgt gatataatag tttcgaataa
     7081 aataaataaa ggagtttttg taacatggca aaacttactg ttaaagacgt tgacttgaaa
     7141 ggtaaaaaag tcctcgttcg tgttgacttc aacgtaccat tgaaagatgg cgtaatcact
     7201 aacgataacc gtatcacagc agctcttcca actattaagt acatcatcga acaaggtgga
     7261 cgtgcaattc ttttctctca ccttggacgt gtgaaagaag aagctgataa agctggtaaa
     7321 tcacttgctc ctgtagcagc agacttggca gcaaaacttg gtcaagatgt tgttttccca
     7381 ggtgtcactc gtggtgctga attggaagcg gcaatcaacg ctcttgaaga tggacaagtt
     7441 ctcttggttg aaaacactcg ttacgaagat gttgacggca agaaagaatc taaaaacgat
     7501 cctgaacttg gtaaatactg ggcatcactt ggagatggta tcttcgtaaa cgatgcattc
     7561 ggtacagctc accgtgcaca cgcatctaac gttggtatct cagcaaacgt tgaaaaagca
     7621 gttgctggtt tccttcttga aaacgaaatt gcctacatcc aagaagcagt tgaaactcca
     7681 gaacgtccat tcgtggctat ccttggtggt tcaaaagttt cagacaagat cggtgttatc
     7741 gaaaacttgc ttgaaaaagc tgataaagtc cttatcggtg gtgggatgac ttacacattc
     7801 tacaaagcac aaggtatcga aatcggtaac tcacttgtag aagaagacaa attggatgtt
     7861 gcgaaagctc ttcttgaaaa agcaaatggt aaattgatct tgccagttga ctcaaaagaa
     7921 gctaacgcat ttgctggtta cactgaagtg cgtgacactg aaggtgaagc agtttctgaa
     7981 ggcttccttg gtcttgacat cggtccaaaa tctatcgcca aatttgacga agctttgact
     8041 ggtgccaaaa cagttgtatg gaacggacct atgggtgtat ttgaaaaccc agatttccaa
     8101 gctggtacaa tcggtgtgat ggacgctatc gtgaaacaac caggagttaa atcaatcatc
     8161 ggtggtggtg actcagctgc cgcagcgatt aaccttggcc gtgcagacaa gttctcatgg
     8221 attagtacgg gtggtggagc atcaatggaa cttcttgaag gtaaggttct tccaggactt
     8281 gcagccttga cagaaaaata agattttata aacaaatcaa agaagagagg gatgaaagtt
     8341 cctcttttct tttgcttaaa ataaaaacgc ttcctctcaa ctattactca taaaaatcac
     8401 cgatttatga taaaatggaa atagaaagtt gagattatga gttattttaa aaaatataaa
     8461 ttcgataaat cccagttcaa acttggtatg cgaaccttta aaacaggtat tgctgttttt
     8521 ctagttctct tgatttttgg cttttttggc tggaaaggtc ttcaaattgg tgctttgaca
     8581 gccgttttta gcctgaggga gagttttgat aagagtgttc attttgggac ttcgcgtatt
     8641 ctaggaaata gtatcggtgg actctatgcc ttggtcttct tcttattaaa tacctttttc
     8701 cacgaagcct tttgggtgac cttggtagtt gttccaatct gcaccatgtt aaccattatg
     8761 acaaatgtag ccatgaataa caaagcaggg gttattggtg gtgtagcagc tatgttaatc
     8821 attaccctat caattccaag tggtgagaca atttcgtacg tgtttgtgcg tgtatcagaa
     8881 acgtttatgg gagtttttgt cgcaattatt gtaaattacg atattgatcg tattcgtctc
     8941 tttttagaga aaaaagaaaa ataatgttac attttataac attatcaatt gacgtttgtc
     9001 tttttttaga ctataataga cagaaagaag gaaattgtaa atgaaggaaa aagaatttcg
     9061 ccgaaatatg gctgtttttc ctatcggcag tgttatgaag ttgaccgatt tatcggcgcg
     9121 tcagattcgt tattatgaag atcaagagtt gatcaagccc gatcgaaacg aaggaaatcg
     9181 tcgcatgtat tccttgaatg acatggatcg tctgcttgaa atcaaagatt atatctctga
     9241 aggttataat atcgctgcca ttaagaaaaa atatgctgaa cgtgaagcga aatccaagaa
     9301 agcggttagt cagactgaag tacgtcgtgc acttcacaat gaactcctcc aacaggggcg
     9361 ttttgcttca gtacagtcac cttttggtcg cggttaggca accgcaagta gtcatagatt
     9421 aaggagaaaa cttatgccaa tcacagctgc agatattcgt cgtgaagtca aggaaaaaaa
     9481 tgttaccttt attcgtctta tgttctcaga tattttggga accatgaaaa acgtcgaaat
     9541 tcctgctaca gatgaacagt tagataaggt cttatcgaac aaggttatgt ttgatggatc
     9601 ttctattgaa ggttttgtac gtatcaatga gtcggatatg tacttgtacc cggacttgga
     9661 tacatggaca gtcttccctt ggggagatga aaatggaagt gttgcaggtc tgatctgtga
     9721 tgtctataca acagaaggtg aaccatttgc gggtgaccct cgtggtaatt tgaaacgagc
     9781 tcttcgtcac atggaagaag ttggattcaa atccttcaac cttggtccag agccagaatt
     9841 cttcctattt aagttggatg aaaatgggga cccaacactt gaagtgaatg acaagggtgg
     9901 ctactttgat ttggcaccta ctgaccttgc ggacaacaca cgtcgtgaga ttgtgaatgt
     9961 cttgaccaaa atgggatttg aagtagaagc gagtcaccac gaggttgcgg ttggacagca
    10021 tgagattgac tttaagtacg atgaagttct ccgtgcttgt gataagattc aaatctttaa
    10081 acttgttgtt aaaaccattg ctcgcaaaca cggactttac gcaacattta tggcgaagcc
    10141 aaaatttggt attgctggct caggtatgca ctgtaatatg tccttgtttg atgcagaagg
    10201 aaataacgcc ttctttgatc caaatgatcc aaaaggaatg cagttgtcag aaacagctta
    10261 ccatttccta ggcggtttga tcaagcatgc ttacaactat actgccatca tgaacccaac
    10321 agttaactca tacaaacgtt tggttccagg ttatgaagcg cctgtttaca ttgcttgggc
    10381 tggtcgtaac cgttcgccac ttgtgcgcgt acctgcttca cgtggtatgg gaactcgtct
    10441 tgagttgcgt tcagtggatc caatggcgaa cccttacgtt gctatggctg ttcttttgga
    10501 agttggtttg tatggtattg aaaataaaat cgaagcacca gctcctatcg aagaaaatat
    10561 ctacatcatg acagcagaag agcgcaagga agctggtatt acagaccttc catcaactct
    10621 tcacaacgct ttgaaagctt tgacagaaga tgaagtggtt aaagctgctc tcggagatca
    10681 catctacact agcttccttg aagccaaacg aatcgaatgg gcaagttatg caaccttcgt
    10741 ttcacaatgg gaaattgata attatttaga cctttactaa tactaatata gaagaaagat
    10801 tgcctgtggg taaacagtca cacagcagtc taagccatca aatacctata acccttaaaa
    10861 tagcgatttc ggtcgctatt tatttttcga aaaatcctct tgactctttt gcgaattaga
    10921 tttatcatca gacgtgtaga agaaaatcaa ggagtcacta tggaaaaatt caatttcaaa
    10981 aacaatatcg ggcaagaaaa caagttactt caaatcgaaa tctacaagtt tactaacttt
    11041 tacaagcttc aaaattacac atctgtaaat attttttcga aagatatatt tgaagccata
    11101 gtaaattgag actagaatag tacactacat ctgctaaaaa tttctagaaa ctaatttaac
    11161 tttcctaatc gatttgttta catcttattt caatctacta tattatctca ataaatgatg
    11221 atggcgactg ttttgtttgt gcttgtcgat ttttgaatcc ctgatcgagc ggaagaatat
    11281 ttctgccgag gttgccaagg ggaaaatact gaagatattg aattttatga taaacaatta
    11341 caggcagaaa aggtggaggt tttgaatatt cgattggaag taaaaaattg aattatctac
    11401 aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt tttacgcctt
    11461 tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga agtactcaag
    11521 aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggata aaatcaattt
    11581 attggaattt tgggcaaaat aagccagaga aatcctttag gtatatagat acgt
//
LOCUS       DAVMCN010000051        11493 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVMCN010000051 DAVMCN010000000
VERSION     DAVMCN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.052"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..826
                     /locus_tag="VYP85_001644"
     CDS             <1..826
                     /locus_tag="VYP85_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1882126.1"
                     /translation="ENNRKRSVKKSSLTKELKEKILHYHNQKFSPEMMVMAKGVNVGI
                     STIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQSIEQRSEAINLRLENGH
                     YEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVNQALKLILKQHKILSITA
                     DNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFI
                     EKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
     gene            798..1442
                     /locus_tag="VYP85_001645"
     CDS             798..1442
                     /locus_tag="VYP85_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1882127.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(1484..3472)
                     /locus_tag="VYP85_001646"
     CDS             complement(1484..3472)
                     /locus_tag="VYP85_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1882128.1"
                     /translation="MFRLTNKLAVLNLIKNRKLYYPFALAVLLAVTLTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDNGYKIKEKEVFRYTYFGVANQEGNKLTFFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(3474..4232)
                     /locus_tag="VYP85_001647"
     CDS             complement(3474..4232)
                     /locus_tag="VYP85_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882129.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4660..4851
                     /locus_tag="VYP85_001648"
     CDS             4660..4851
                     /locus_tag="VYP85_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882130.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(5205..5477)
                     /locus_tag="VYP85_001649"
     CDS             complement(5205..5477)
                     /locus_tag="VYP85_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1882131.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGRFW"
     gene            complement(5536..5985)
                     /locus_tag="VYP85_001650"
     CDS             complement(5536..5985)
                     /locus_tag="VYP85_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1882132.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(5972..8101)
                     /locus_tag="VYP85_001651"
     CDS             complement(5972..8101)
                     /locus_tag="VYP85_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1882133.1"
                     /translation="MDKKYEKISQALGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGKKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            8513..9418
                     /locus_tag="VYP85_001652"
     CDS             8513..9418
                     /locus_tag="VYP85_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1882134.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSIVVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSHLSPAKKVFQVFVQAIDEFFDTGRYLVFGCLFASVIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            9415..10230
                     /locus_tag="VYP85_001653"
     CDS             9415..10230
                     /locus_tag="VYP85_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1882135.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQVTNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(10359..11075)
                     /locus_tag="VYP85_001654"
     CDS             complement(10359..11075)
                     /locus_tag="VYP85_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1882136.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEEFICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(11079..11390)
                     /locus_tag="VYP85_001655"
     CDS             complement(11079..11390)
                     /locus_tag="VYP85_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882137.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKECEELRQIITTIFEQKMNKHSI
                     K"
BASE COUNT         3422 a         2398 c         2181 g         3492 t
ORIGIN      
        1 tgaaaacaat cgcaagcgct cggtcaagaa atcaagcttg accaaggaac taaaggaaaa
       61 gattctccac tatcataacc aaaaattttc gcctgaaatg atggttatgg ctaaaggggt
      121 taacgtggga atttcaacca tttactattg gattcatcat ggaaaattgg ggttaagcaa
      181 gcaggatttg ccttacccta gaaaaggaaa agcgcttaag aaacaggcta gcaccaactt
      241 taaacctgct ggtcaatcta tcgaacagcg gtctgaagct atcaatcttc gcttggagaa
      301 tgggcattat gagattgata cggttctact tacgagagcg aaaaactact gcttgcttgt
      361 cttgacggat cgaaagagta gacatcagat catccgattg attccaaata aaagtgctga
      421 ggtggtcaat caggctctaa aactcatctt aaaacaacac aagattcttt ccatcacggc
      481 agataatgga acggaattca atcgcttgtt tgatgtattt tctgaggagc acatctatta
      541 tgcgcacccc tatgcctctt gggaaagggg aactaatgag aatcacaaca ggctcattcg
      601 tagatggtta cctaagggaa ccaagaaaat gactcccaaa gaagtcgcat tcatcgaaaa
      661 gtggattaac aactatccta aaaaatgctt ggactacaag tcacccagag aagacttctg
      721 gatggctaac ttgaacttga aatttagcgt cagaaacaaa tcacgaaatc gattcaaatt
      781 ttgcaggtcg tttaaatatc ctgcgcgcag gtgttcttgg tgctaacgat ggaattattt
      841 ccattgctgg tgtggttatc ggggttgcca gtgccacgac caatatctgg attatctttt
      901 tatcaggatt tgcggctatc ttagctggtg ccttttcaat ggctggtgga gaatatgtat
      961 ccgtttcaac tccaaaagat accgaggaag ctgccgtttc gcgagaaaaa ctcttgttag
     1021 accaagatag ggaactagcc aaaaaatccc tctatgctgc ttatatccaa aatggagaat
     1081 gcaaaacttc tgcccaactc ttgaccaata agatctttct taaaaatcca ctcaaggctc
     1141 tggtagagga aaaatatggg attgagtatg aagaatttac caatccttgg cacgctgcca
     1201 tttctagctt cgttgccttt ttccttagaa gtttgcctcc aatgctgtca gtgaccatat
     1261 tcccaagtga atatcgcatc cctgctactg tccttattgt cggtgtggcc cttcttctca
     1321 ctggttacac tagtgccaga cttggaaagg atccgactag aacagctatg attcggaacc
     1381 ttgctattgg tctcttgacc atgggagtta ccttcctgct cgaacaactt ttcagcattt
     1441 agaatacaag aaatacctcg attttgaagt cgaggtatct tttttacatt tgcacaatct
     1501 tgcgataact tcttgaagta atcatgaaaa tcagcacata ggcgatgagg aagatagcgc
     1561 agatagacaa ggtcacaatc aacatcatag tcgtatccag tacaccaatc acttttaaaa
     1621 tcaggctaag catatggtag gcaaaggcga gatgtatgaa ggcaaagagc aaaggaagga
     1681 agaaaacagt taaaacctgt ttgttgatgg tttgcttgat ttgcttttgg tccaaaccga
     1741 ctttctgcaa gataataaag cgttcacggt cttcgtagcc ttcagaaatt tgtttgtagt
     1801 agatgaccag aacagttccg accataaaga taatggatag gaaaataccg ataaagaaga
     1861 caccaccaaa gagggcactc atctgagaac tagcatctgc tagattgcta ccataaacat
     1921 agctaccttc tgtgtctaat tgagcattaa attgattgag gtagttttca tactcctcag
     1981 cgaccttgag ttgttcttct tcgctggcat ctacattcat accaccgtaa aactgattat
     2041 agatagccga atctgggaat tgatccaaaa aggcttgtaa atcaggaaca acaaggtaat
     2101 tgtaatcagt agtcaagata ttaaacttat ttggaacatg gttgacaatg aaatctttat
     2161 taaattcttc tttgacagaa aattgatgat catttagagt tagagctttc tgtcctttca
     2221 gtccgtcatt tttggcaaag agaccgacct catttcctga tagagacagt ttttgaccag
     2281 tcatattttc ataatctttt tggtcaaata ccatgaaaac tgttgtgggt tggacacgat
     2341 tttgtccttt ttcaaaaaag gttaacttat ttccttcttg gttcgcaaca ccaaagtaag
     2401 tgtaacgaaa cacttctttt tctttaatct tataaccatt gtcacttgca aactggctca
     2461 agagtttgtc caaatcttct ttttcaacat tttgtcctga aaccccaaaa tcatgaggat
     2521 ttagaacttt tttaaaggat tctgcggaat tgaaaatgct tgtcgctgct gacatggtta
     2581 ccaaaaccat tgttgacaaa atagcgatag ttgctagtcc aactgcattt ttcttcatac
     2641 ggaaaatcaa gttagaaaca gatatgaggt tatttggttg gtaatagtat ttcttatttt
     2701 tctttaagat ttggaggaaa acggtaatcc ctgcattaaa caagagataa gtcccaaaga
     2761 taaccagtaa aacagctatg aagaaggttg ttaaggctgt aagaggatct tttaccgtaa
     2821 gggcaagata atagccaatt cctaaactta tggaaccaag aatggtttgg agaggaagga
     2881 agcgaccttt tttctctcca ctagctttct cacgagagag ctggagggca ttcatacggg
     2941 cgattcgaag ggcattcagg aacatgaggc ctaggaaaat caaaccgaag acaacaagca
     3001 ctgtaatgac aactttcgtc tggaaggtag caaccagctc aaccttcaat ttcattagtt
     3061 tgagcaggaa agcgaaaatt aacttgtcaa acaaggctcc aataccgata cccgctccaa
     3121 cagttagaat cccaaatacc actaactcct taaaggtcat actgataaga tgacgcttct
     3181 ccaagcccaa catgccataa attcctagtt ccttggaacg gttcttcatg acaaaactat
     3241 tggcatagag aacgataatg gctgacgcaa gggtgacgac aaacatacca aatccaagtg
     3301 tagcctgaat ggttgttcct ccacggattt ccgcaatctt aggattgaag gttagagagt
     3361 aaaagagata ggtgagagtg actgccaaga gaacagccag cgcaaaagga tagtagagtt
     3421 tgcggttttt aatcaagttc aataccgcta acttattggt taatcgaaac atactaattc
     3481 acctcgcttg ccatgacagt caaggtatca gagatttctt ggaacatctg acgttctgtc
     3541 ttctctccac ggtagatttg attgtaaaga atgccgtctt tgataaagag tacacgttta
     3601 gctctgctag ctgctgctgt tgagtgggtt accatgagaa tggtttggcc gcgctcattg
     3661 atttcatcaa agacatcaag taaggctgca gatgacttgg agtcaagagc tcctgtcggt
     3721 tcgtccgcaa ggagaatttc aggttcagtg atgatggcgc gtgctactgc tacacgctgt
     3781 ttctggccac cagaaatctc gtaagggtac ttctcttgta attggtttat tcccagattc
     3841 tcagctgtca ccaccaattt cttcatcatc tctgtaatag gtcttcttga caagacaagc
     3901 ggaagcaaga tattgtcctt tacagataga gtatctagca agttaaagtc ttggaagaca
     3961 aagcccaact tttcacgacg gaagctagag gcctgtgaat ttttaatggt tgcggtgtca
     4021 gttccattca agtaaacctg accacgactt ggtttatcca gcatagctag aatattgaga
     4081 agagttgatt taccagaacc agactcaccc atgatggcaa cgtagtcacc cttttcgacg
     4141 gtaaagtgaa tatccttgag ggcttctact tggttgccct gaaaacgtgt tttataaatt
     4201 ttttgaacgt gttttacatc taaaagtgtc atgagaatct cctttcttaa tatcccatca
     4261 aatgaaatgt agcttgcatc atagtgcatc ccagctgaac gcgctcaatt tctttgtgac
     4321 ttggttttct agttttctta tgtaagattt gtttcatgat gttactcctt tgttctttat
     4381 gagtctagtt tacatcaaaa aaagaccgct tgccataacc taaccttaca aaagagactt
     4441 taatcttaca tttttgtaag attgggtgaa atataagcaa aattacttag aaaatgattt
     4501 gatttcctat ttttaaagtt gtaaaatata agtgtgaaaa ggcttacttt gaaaaggagg
     4561 aagcgggaac taacatttta gtaaggttac ctagataaca taccattcaa tttaacactt
     4621 gcaagtcgtt caacctataa ggaaagaagg tgcgctttaa tgaaacacaa agaacatata
     4681 ctcatcggac ttctctatct gctctctcca ttcatcggtc agctcttagt tgaacacaca
     4741 cactttatcg gtacagaatt taccggcact gcttatgtta tttgctggtt atcagttgtt
     4801 atcagcatcc accatttttc caaaaatgta ttgtctcagc agcaaaaata gattaaaaaa
     4861 ctgagtttaa attactgctt ttataataaa atgaaataag aacaggacaa atcgatcagg
     4921 atagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagttccaat
     4981 ccactatagt ttgtggatga agctggcgaa atattattaa tactattcaa aaatcaaagt
     5041 gcaaactatg tcaacttcac attgccgact aaattacagc ctgtggctgg cttcctagtt
     5101 tgcactttga tttttattga gtataaaagt aaaaaagctt taaatcaagc agtttagact
     5161 attgatttaa agctttttgc ttattccaaa tcttctgtag aacctcacca aaacctgcct
     5221 tcattgtcgt caatggcttg ggcttctttg cgtttacgtg ggcctgttcc gtacatttct
     5281 gcttcgattt cttccttggt aggcatgata gaagctagga tgatatagat aatcacgcca
     5341 agtccaaagt ttgcaactgt aaaaatggca aacaagaaac gaactagggt aacatcaaaa
     5401 ttccacttgt ctgacagacc tgccagaact cctgaaatca tgcgattgcg tctcatttta
     5461 taaaatttac tgttcatgat atttcctctt tctgctaggt tagacatagt atatcacggg
     5521 gaggctcggc tttcatcagt cctcaggctg atttatcaga agcaatttac ctcgacaaag
     5581 tccacagcga tagcgtttgg tatcaatcct acgcttgcgc tgataccttt gctggcagga
     5641 ttgacaacga taaagcttga gtggtttaga gttactattg ggcaaggatg gtacaaaccg
     5701 taatccatcc actgctttca aaagttcctt aaaatcccga tccttgtgtt gatagccctt
     5761 cccttggaaa taaaggtgat aatgacagag ttcatgtcgg acaattttcc taaaaacgtc
     5821 caaccccagt tcctgataaa ccttgggatt aaaatccaaa tgcccatctt tggggaaaaa
     5881 tcgcccacct gtcgaacgta gacgcctatt ccactggaca tgatggataa aaggtctgcc
     5941 gaagtcttct agtgaaacct gcttgacgta atcagtcagt ttcatttgga gctaggagag
     6001 acagattaac tttttcacgt tcagtatcaa ttttcttaac ccaaacgctc accaaatctc
     6061 caactgccac cacttgacta gggtgtttga taaacttgcg actcatatgg gaaatatgga
     6121 tgagaccgtc ctcatgaatt ccgatatcaa caaaagcacc gaaatcaaca acgttacgca
     6181 ccactccttc tagctttttt ccaaccacta agtccttgat atctaggaca tcttgacgga
     6241 gaactggagc atcaaaggaa tcacggaaat ctcgacctgg tttgagaaga tctgcaatga
     6301 tatctttaag agtttctgga ccaaggtcta actcttgcgc catttccttg actgaaagcg
     6361 acttgagttt gctttgggcc tcttcattca gatccttaat gtccaagcat ttgaagagtt
     6421 ccttaacggc agcgtaattt tctggatgaa ctcctgtatt atcaaggata ttgctacttt
     6481 cagggatacg gaggaaacca gcagcctgtt caaaagcctt ggcccccaaa cgaggaactt
     6541 tcttgatttg ggagcgtgaa gtgatttttc cctcttcctc acggtatttg acgatatttt
     6601 cagaaatggt tttattgagt ccagctacgt gtgaaagaag agctgggcta gctgtattga
     6661 cattgacacc aacttggtta accactgtat cgacaacaaa gtccagactc tcagagagtt
     6721 tcttctgact gacatcgtgt tggtattgac cgacaccaat tgacttagga tcgattttga
     6781 ccaattccgc aagaggatct tgcaaacgac gggcgataga aatggcagag cgtttttcaa
     6841 cggtcaagtc tggaaactcc tgacgagcaa gttcgctggc agaatagaca gaagcaccac
     6901 tttcattaac gataacatag ctgacttcag ggaaatcttt cagaacttcc gctacaaaag
     6961 cttcactttc acgactggcc gttccatttc caatggcaat aatctctaca ccgtattgac
     7021 caattaaatc tgctaaatct ttcttggctt cttcgatttg acgagctgat gctggtttaa
     7081 caggataaat aacctgagtt gtcagcattt ttcctgttgc atccacgaca gctagcttgg
     7141 cacctgtacg aaaggctggg tcaaacccaa gaaccacgcg ccctttcagt ggagcaacca
     7201 agaggagatt gcgcagattg tcagaaaaaa gttggatagc tccctcttca gctttctcag
     7261 ttaattctgt ccgaatacga cgctcaatag caggcaagac ctttttctta acggattgct
     7321 gaacaacttc atcaatataa gcatttttca ccttgaaacg agtagcaaag aaggcaagaa
     7381 tacggtccgt cgcatgttca aaaccgatct tcaagacacc aagtttctcc ccacgattga
     7441 gagccaaggt acgatagcct tgcatagttc caactgtctc tgaaaaatca taataaatct
     7501 gaaaaacctg cttttcatca agactttcat ccttggcttg agaagtgagt ttagagtgtc
     7561 tcagcacttc ctgataagtc atagaacgca aggtcacatc ttccgataag gcttcgacca
     7621 aaatatcaac tgcaccggtc aaggcttcct tgccagtcgc aaatccttca cagacgaact
     7681 tttcagcttc tttctctaag tcaactatat tctgcaaaat caagcgagca agaggaaaga
     7741 gtccagcttc acgggcaatg gttgccttgg tacgacgctt ttccttataa ggaagataga
     7801 gttcttcaac gtctgctaat ttttcggcaa ctaagatagc ttcttccaat tccttggtca
     7861 acttaccttg ttcttgaatc ttagctaaga cagcttcctt acggtcattg agatttgtca
     7921 gacttttatc caaatcaata atagccttaa tcgccacctc atccagacta ccagtcatgt
     7981 ccttgcgata acgcgcgata aagggaatag tcgccccttc agctgtcaaa cttagaacgg
     8041 tatcaatttg ctttaacgtc actcccaaag cctgagagat tttttcatat tttttatcca
     8101 taaatctatt ataccacaag ctggaaggct ttctccaatc cttttcatac tcaataaaaa
     8161 tcaaaaagca aactaggaag ctagccgtag gctgctcaaa atactgtttt gaggttgtgg
     8221 atagaactga cgaagtcagt aaccgtacta cggtaaggcg aagctgacgt ggtttgaaga
     8281 gattttcgaa gagtatcaac tatcgaaaac aaattaaaaa actccctttt ccgcaaaata
     8341 atagtataat agaggtagaa tttagaatcg aggtacacct atggctgtca aatttacaaa
     8401 acgagacgac ttggacaaga tgtttgaaga gtttgctaaa ctccctgatt tgaaacaagt
     8461 cactttccct gatgacaaag agaaaaaagc caaagcagaa aagaaaaact agatgactgc
     8521 ttttcaacaa ctcccatcta gtgtacttca aactggagcc atttttctct ccattatcat
     8581 tgaagccctt cccttcgttc tgataggaag tattgtctca gggctgattg aagtttatat
     8641 cacacctgac aaggtttatc attttctccc tcgaaatcgt tgggggagaa tcttttttgg
     8701 gacctttgtc ggtatacttt tcccttcctg tgaatgtgga atcgtcccca tcatcaatcg
     8761 ttttctggaa aaaaaggttc caagttacac ggccgttcct tttcttgtga cagcacctgt
     8821 tatcaatccc attgttcttt ttgcgaccta ttctgccttt ggcaactcct tccatgtcgc
     8881 cctattacga gctctgggtt ccatcgttgt ggctgtaata ctaggaattt ttctaggatt
     8941 tttctggcaa gaaccgattc aaaaagaaaa tcgtctagcc tgtcatgagc atgatttttc
     9001 tcacttaagt cctgcaaaaa aagtttttca ggtctttgtg caagccattg atgagttttt
     9061 tgatacggga cgttatttgg tatttggctg tctctttgcc tctgttatac aggtttatgt
     9121 tccgactcgg attctgacct ctatcagtgc gactcctctt tttgccatcc tgctcttgat
     9181 gattttggcc tttcttcttt cgctctgtag tgaggcggat gcctttatcg gggcttctct
     9241 actctcgagt ttcggtttgg ctccagttct ggcttttctc gtcattggcc caatgctgga
     9301 tatcaaaaat attcttatga tgaaaaatta cttgaaagca cgatttatta gtcacttcat
     9361 tacgattgtg actctggtcg ttttagccta ttctctcttg attggagtca tcctatgatt
     9421 cgatttttag ttttagctgg ctattttgaa ctgactattt acctccatct gtcgggcaaa
     9481 ctaaaccagt acatcaacat gcactattcc tatctggcct atatctccat ggtgctttct
     9541 tttatcttgg ctatcgttca attgtatatc tggatgaagc aagtcaaaac ccacagtcat
     9601 ctgaacagcc gattagccaa gatgacgagt atttctcttc tggctattcc acttgtcatc
     9661 ggcttaactt tcccaactgt tagcttggat tctcagactg tttctgctaa aggttatcat
     9721 ttccccctat cggaaggaac ggatctagcc attcagacaa gcgaagggac gacaagccaa
     9781 tatttgaaac cagataccag ttcttatttt tcaaaatcag cctatgaaaa ggaaatgcga
     9841 acggcggcgg ataaatactt atcccaagat agtattcagg tcactaatga aaactatatg
     9901 gaagtcatgg aggctatcta cgactatcca gatgagtttg agggcaagac aatccagttt
     9961 acaggctttg tctataacga ccccagtcat gccaatagtc aatttctgtt ccgattcggc
    10021 attatccact gtatcgcaga ttctggtgtc tatggattgc tgaccaaggg caatacccgg
    10081 cagtatgaaa acaacacttg gataacagcc aaaggaaaac tggtcaatca ctaccataaa
    10141 gaactcaaac aaaaccttcc aaccttggaa atcgacagct ttaccaaagt cgataaacca
    10201 gaaaatccct atgtatatag agctttttaa gaaaatcaag ataaaaacga acaagttctc
    10261 ttctgaataa cagaaaaaga gcctgttcgt tttttgttat atgaaaatta gtgacttgta
    10321 gattttcatc ttataccatt tccagcaata caagtagctc atagaaaata agcgagccac
    10381 tcattcatta gactagcgat ttctttaggt gcttgagtat aaagctcatg gccaaagttt
    10441 tctaaaaaaa tagtatcaaa atagtctggc aattctttta gggcttcctc tctccatgta
    10501 gcttcattag gatagcgagg actaataaac aaggtatctc ccacttctct cttaaaagct
    10561 tgtatttttc tccgtaggcg gagtatcgct tctatatttt cataatttat agccaactca
    10621 tatctattat actcaacatt ccagtgatag gactgtctta cagctttctc catattttct
    10681 gaccaatgct ttgcttcaga tttttcttta gaagtaagaa catctaagtc caaaacaatt
    10741 tgagatttga tataattttt agtttcctct aactctgtat ccaaaggtaa aatcttatct
    10801 aaatctagat agccaccatc caaaagaatc agtttcttta cttcttcaaa ttccgatgcg
    10861 agataacgag ctaaatctcc tccaagagaa tgacctatca gacagataaa ttcttcctct
    10921 acaatctcat ttttaaacca tgatttcaat tctgtttcat ctcgaagatg cttttcatat
    10981 ggatttagaa aatagacctg cgaatctagt tcttgaagaa aatccttgct atgataggca
    11041 ttgcttccca aaccgccaat aaaatatttt ttcattctct acttaatact atgcttattc
    11101 atcttttgtt caaagatagt tgtgataatc tgacgcaatt cttcgcattc tttttctgga
    11161 atctcaccac ttgtttgagc tacagcgtag agttcagggt gttcaattga aatgcgttta
    11221 atcgtacgtg ttgtagcatg ttttctgaca aaaaacggga ttcgcttaat caagtcttgt
    11281 ggtactagcg ccagaatctt ctcagtagtt tctttgtcac taatattaga cattgtaagc
    11341 cttttcttaa tcatttcctg ttctttttct gtaaaatctt ttaattccat tcgattagtc
    11401 ctcctatttt ctctaagtta aattatgtac taatacagat gaaattacaa agaataaact
    11461 ttaagaaatc ttctcactga taagatttta gca
//
LOCUS       DAVMCN010000052        11177 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVMCN010000052 DAVMCN010000000
VERSION     DAVMCN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.053"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            85..470
                     /locus_tag="VYP85_001656"
                     /pseudo
     CDS             85..470
                     /locus_tag="VYP85_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1005..1697
                     /locus_tag="VYP85_001657"
     CDS             1005..1697
                     /locus_tag="VYP85_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1882138.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1750..4161
                     /locus_tag="VYP85_001658"
     CDS             1750..4161
                     /locus_tag="VYP85_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1882139.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQVAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4411..5112
                     /locus_tag="VYP85_001659"
     CDS             4411..5112
                     /locus_tag="VYP85_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882140.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPAQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5114..7822
                     /locus_tag="VYP85_001660"
     CDS             5114..7822
                     /locus_tag="VYP85_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1882141.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMETTANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7918..8409)
                     /gene="tpx"
                     /locus_tag="VYP85_001661"
     CDS             complement(7918..8409)
                     /gene="tpx"
                     /locus_tag="VYP85_001661"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1882142.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8532..9461)
                     /gene="psaA"
                     /locus_tag="VYP85_001662"
     CDS             complement(8532..9461)
                     /gene="psaA"
                     /locus_tag="VYP85_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1882143.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9493..10341)
                     /locus_tag="VYP85_001663"
     CDS             complement(9493..10341)
                     /locus_tag="VYP85_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1882144.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10338..11060)
                     /locus_tag="VYP85_001664"
     CDS             complement(10338..11060)
                     /locus_tag="VYP85_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1882145.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3290 a         2070 c         2538 g         3279 t
ORIGIN      
        1 tattttataa tatcagaaca tacttttttt aaaagcaaat atgatacaat tttatttgaa
       61 aaaaataaaa aaggagattt tattataaaa ttaaaaagac ttgctttaat tagtggtatc
      121 gtcggtcttg tgggaggaat tttacttctt attggtcctt ttgtcttgtt gggaatagcg
      181 gtaaacacag ctgctacaac tcttaatgga ggagctactg caggggcttt ttcaggtgta
      241 gccttactct tgaatgcctt gaagattgca aatcttgttc ttggtatcat tgctattgtt
      301 tactataaag gagataagcg tgtaggtgca gctccgtctg tactaatgat tgtttctggt
      361 ggagttagtc tcattctatt ccgttcttag gatgggttgg ggggattttt gctattatcg
      421 gaggatctct attcctttca acattgaaga aattcaaatc agaagaataa aaggtatttt
      481 agcatgaaaa gaacaaaaaa gtttatcggt ataggagtag ctctattatc tctttctctt
      541 ctagttgcat gtggaacata aagttcaaag aatacttcaa caagtaatga tgagaagaca
      601 gtagcaacat ccaatagttc aaaagaaaca atcactttcg atacaccggt tgtaacagac
      661 gatgcgattg aatcaatacg cacttatgca gattatatag atctttataa aaatattttt
      721 gatgattatt ttactaaagc tgaggaaggt ttcaaaggca tagctatgga aaataatgac
      781 tcgtttacta aactaaaaga gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta
      841 aataatgaag atagaataga aacaaccaaa aacaatgtga ttgccaaaca ttgtcaaaca
      901 gtcctttcct ttttggtttt gactagcttt tttgtgaaaa attgtgtaaa atagaataga
      961 taaacgaggg gaaacctcgg aaaatttaaa ggagaatcca tctaatggta aaattggttt
     1021 ttgctcgcca cggtgagtct gaatggaaca aagctaacct tttcactggt tgggctgatg
     1081 ttgatttgtc tgaaaaaggt acacaacaag cgattgacgc tggtaaattg atcaaagaag
     1141 ctggtatcga atttgaccaa gcttacactt cagtattgaa acgtgctatc aaaacaacta
     1201 acttggctct tgaagcttct gaccaattat gggttccagt tgaaaaatca tggcgcttga
     1261 acgaacgtca ctacggtggt ttgactggta aaaacaaagc tgaagctgct gaacaatttg
     1321 gtgatgagca agttcacatc tggcgtcgtt catacgatgt attgcctcca aatatggacc
     1381 gtgatgatga gcactcagct cacacagacc gtcgttatgc ttcacttgac gactcagtaa
     1441 tcccagatgc tgaaaacttg aaagtgactt tggaacgtgc tcttccattc tgggaagata
     1501 aaatcgctcc agctcttaaa gatggtaaaa acgtattcgt aggagctcac ggtaactcaa
     1561 tccgtgccct tgtaaaacac atcaaaggtt tgtcagatga tgagatcatg gacgtggaaa
     1621 tccctaactt cccaccattg gtattcgaat tcgacgaaaa attgaacgtt gtttctgaat
     1681 actaccttgg aaaataaaaa attgtaagcc taggattgat ttctaggctt tttatgttag
     1741 tatggaagta tgataaggaa taaaaaacaa gattatgtac tggcctacaa acaaccagct
     1801 tcaaccactt acatgggttg ggaagaagaa gctttaccga taggtaatgg ttctttagga
     1861 gcaaaagtat ttggccgtat aggggctgaa cggattcaat ttaatgaaaa aagtctctgg
     1921 tctggaggtc cacttcctga tagttcagat tatcagggtg gaaatcttca ggatcagtat
     1981 gtttttttag ctgagattcg gcaggctttg gagaagagag attacaatct ggctaaggaa
     2041 ctggctgagc agcacctaat tgggccaaaa acgagtcaat atgggaccta tctgtctttt
     2101 ggggatattc acattgagtt cagccagcaa ggtacgactt tgtctcaggt gacggactat
     2161 cagagacagc tgaatattag taaggcactt gtgacgactt cttatgtcta taagggaacg
     2221 cgatttgaac gtgaagcttt tgcgagtttt ccagatgatc tcttggttca gcgttttact
     2281 aaggaagggg cggaaactct agattttact atagaactat ccttgacctg tgatttggct
     2341 tctgatgaaa agtatgagca ggaaaaatct gattacaagg agtgtaagtt ggatattact
     2401 gattctcata tcttgatgaa gggaagagtt aaggataatg atctgcggtt tgctagttat
     2461 ctagcttggg aaacggatgg agatattaga gtttggtcag atagggttca gatatcagga
     2521 gccagttatg ccaatctctt cttggccgct aagacggatt ttgcccaaaa tcctgctagc
     2581 aattatcgca agaaactaga tttagagcaa caggtgatag acttggtgga cacagctaaa
     2641 gaaaagggct atacccaatt gaaatcaagg catatcgagg actaccaagc cttattccag
     2701 cgtgttcaat tggatttgga agctgatgtt gacgcatcca ctacagatga tttgttaaaa
     2761 aattataagc cacaagaagg gcaggctttg gaggagctgt tcttccagta tggacggtat
     2821 ttattgatta gttcgtccag agactgccca gatgctctac cagctaacct acagggagtc
     2881 tggaatgcgg tcgacaatcc tccttggaat tcggactatc acttaaatgt caatctgcag
     2941 atgaattatt ggccagccta tgttaccaat ctcctagagg cggtctttcc ggtcatcaac
     3001 tatgtagatg atttgcgtgt ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc
     3061 tctcagaaag gtgaggaaaa tggttggttg gttcatactc aagcgactcc ctttggttgg
     3121 acggcacctg gttgggatta ctattggggt tggtcaccag ctgccaatgc gtggatgatg
     3181 caaaccgttt atgaagccta ttcattttat agggaccaag actatctcag ggagaaaatt
     3241 tatcccatgt tgagggaaac ggttcgtttt tggaatgcct ttttacataa ggatcagcag
     3301 gcgcagcgtt gggtgtcttc tccgtcttat tctccagaac atgggccgat ttcgattggc
     3361 aatacctatg accaatctct gatttggcag ttatttcatg attttattca ggttgctcag
     3421 gaattgggac tggatgagga cttgttgact gaggttaagg agaagtctga tttactaaat
     3481 cctttgcaaa tcactcaatc tggtcgaatc agggagtggt atgaggagga agagcagtat
     3541 tttcaaaatg agaaagtgga ggcccagcat cggcacgctt cccatctagt gggactctat
     3601 cctggcaatc tctttagcta caagggacaa gagtatattg aagcggcacg tgctagcctc
     3661 aatgatcgtg gagatggcgg cacaggctgg tccaaggcta ataagatcaa tctctgggcg
     3721 cgtttgggag atggcaatcg agcccataaa ttattggcag agcagttaaa aacatccacc
     3781 ttgccaaatc tttggtgtag ccatcctcct tttcagatag atggtaattt tggtgctact
     3841 agtggcatgg cagaaatgtt actccagtct catgcagctt atctggtacc tctagctgcc
     3901 ctacctgatg cttggtcaac aggttctgtt tcaggcttaa tggcacgtgg acattttgaa
     3961 gtgagcatga gctgggaaga taaaaaactc ttacagttga ccattttatc aaggagtgga
     4021 ggagatttgc gagtttctta tccagatatt gagaagagtg tgattaaaat gaatcaagaa
     4081 aaaataaaag cgaaatgcat ggggaaagat tgtatttcgg tggcaacagc agaaggtgat
     4141 cttgttcaat tttattttta agaagatgtt ataaggcagt aatttgaaac ttccttttaa
     4201 taaggattta agaatatagg cagtttccaa ctagttgaaa aagcgttata atgataatag
     4261 gaagtaatac tcaatgaaaa tcaaagagca caaactagga agctagccgc aggttgctca
     4321 aaacagtgtt ttgaggttgt agatggaagc tgacgtggtt tgaagagaga ttttcgagga
     4381 gtataatttg tttgatagag ggtgggtctg atggcttata ttgagatgaa acactgttac
     4441 aagcgttatc aggttgggga cacggagatt gtggccaatc gtgatgtgaa ttttgagatt
     4501 gaaaaggggg agctggttat tatccttggt gcttcaggtg caggcaagtc aacagttctt
     4561 aaccttcttg ggggaatgga taccaatgat gaaggggaaa tctggattga tggtgttaat
     4621 attgcggatt atagttccca ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt
     4681 tttcagtttt ataatctagt ttctaatctg acagctaagg aaaatgtgga actggcttct
     4741 gaaattgtga cagatgcctt gaatcctgct caggttttga cagatgtagg tctggctcat
     4801 cgtctcaata actttccagc ccagctttct ggaggggagc aacagcgagt ctccattgca
     4861 cgcgcggtag ccaaaaatcc taaaattctt ctttgtgatg aaccgactgg agccttggat
     4921 tatcagacgg gcaagcaggt tttgaaaatt ctccaagata tgtctcgtca aaagggagcg
     4981 acggtgatca tcgtgactca taatggagct ttggcgccca ttgctgatcg cgtgattcat
     5041 atgcacgatg ccagtgtcaa ggatgtggtg ctcaaccagc atcctcagga tattgacagt
     5101 ttggagtact agcatgatca agcgaaaaac ttattggaag gacttaattc agtccttcac
     5161 aggctccaag gggcgttttt tatccatctt gatcctgatg atgttgggat ctctagcctt
     5221 agtaggcctc aaagtaacca gtcccaacat ggagacgaca gctaatgctt atttaacaac
     5281 tgctcaaacc ttggatttgg cagtcatgtc taactatggc ttggatcaag cagaccaaga
     5341 agaactaaaa cagacggagg gcgcagaggt cgagtttggc tatttgacag atgtgactat
     5401 ggataatggg caggatgcca ttcggctgta ctccaaacca gagcgaattt caacctttca
     5461 gctaagaaag ggacgacttc ctcagtcaga caaggaaatc gctttggcca ctcatttgca
     5521 aggccaatac agcgtgggac aggagattag ttttaaagaa aaagaagagg gtcattcctc
     5581 tttaaaagac catacttata ccattactgg ttttgtggat tcggctgaaa tcctctccca
     5641 gcgagatatg ggctacgcag gaagtggaag tgggactctg acagcctatg gggtgatttt
     5701 acctagtcaa tttgatcaga aagtctacaa tatagctcgt ttgaaatatc aagatttagc
     5761 aggtttaaat gccttttcat cagcttatga agaaaaatcc aagcaacatc aggaagagct
     5821 tgaacaaatt ttatcagata atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca
     5881 agagtctcta gacaaggggc aagagaccct tgacaaggct cagactaatt tgcaggaagg
     5941 caagcgtcgt ttagcagctg ctcaagctcg tatacaggct caagaaagtc aactagcctt
     6001 gtttcctcaa gttcagagag agcaggctag tgctcaactt acccaagcca agcaggaatt
     6061 gggcaaggaa gaggccaaac taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa
     6121 attagaaaaa catcagcaag tcttggacga tttggcggag ccaaggtatc aggtctataa
     6181 tcgtcagacc atgccaggtg gtcagggcta tcttatgtat agcaatgctt catccagtat
     6241 tcgagcagtg ggcaatatct ttcctgtggt actttatgcc gtagcagcca tggtgacctt
     6301 tacgaccatg actcgctttg tagacgaaga gcgaactcat gcagggattt ttaaggcctt
     6361 gggttatcgt agtaaggata ttatcgccaa gtttctcctt tatggactag tagctgggac
     6421 tgtcggaacg gctctaggta gtatacttgg tcattatttg ctagccaatg taatttcaag
     6481 tgtcattaca aaaggcatgg tggtgggaga aactcagatt cagttctatt ggacctatag
     6541 cttactagct cttgtcttga gcttgttggc gagtgtgtta ccagcctatc tggtggcttg
     6601 gagggaactt catgacgaag cagcccagct tctacttcct aaacctcctg tcaaaggagc
     6661 taaaatctta ttggagcgta tcggttttat ctggcgtcgt ctcagtttta ctcataaggt
     6721 aacagctcgc aacatctttc gttataagca gagaatgttg atgacaatct ttggtgtggc
     6781 aggttctgta gctctgctct ttgcaggttt gggaatccaa tcttctgtag caggagttcc
     6841 gtctaaacag tttcaacaaa tccaacagta tcagatgctt gtctctgaaa atcctagtgc
     6901 gaccaatcag gacaaggtag agctagcaga agtgttgaaa gggcaggaga tactagccta
     6961 ccagaaaatc tattctaaag cgctagacaa ggatttcaaa ggcaaggctg gtcttcaaaa
     7021 cattactctt atgatgatag agaaggaaga tttgactccc tttatccatc ttcaacatca
     7081 tcagcaggag ctgacattaa aagatggcat cgttattaca gctaaactcg cccagctggc
     7141 aggtgtcaag gttgggcaga ctttagaaat tgaaggtaag gaactaaagg tcgctgctat
     7201 tactgagaac tacgttggtc actttattta tatgagtcag gctagctatg agcaacttta
     7261 cggacagcta ccccaagcca acacttatct ggtctcatta agggatacca gtgcaactag
     7321 tatcgaaagt caggcgggct tgcttatgaa tcaatctgcg gtgtccagcg ttgtccaaaa
     7381 tgcttcagcc attcgactct tcgactctat cgctagctca ctcaatcaga ccatgaccat
     7441 cttggtcatc gtatcggttc tattagctat tgtcatcctt tacaatctga ccaatatcaa
     7501 cgtagctgag agaatccgtg aactctccac tatcaaggtt ctcggttttc ataataatga
     7561 agtcaccctc tacatttacc gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg
     7621 tctggtagct ggtttctatt tacaccaatt tttgattcaa atgatttcgc ctgcgactat
     7681 tctcttttat ccgcaggtag gctgggaagt ctatgtaatc ccagtggcaa cagtaagcat
     7741 cattttgacc ttgcttggtt tcttcgtcaa ttattatctg agaaaggttg atatgttaga
     7801 agccctgaaa tctgtagagt aaggtagtta tttttagctg attgaacttc tatttactaa
     7861 tattcaaaaa tcctccgttt caaagagcag ggagctcttt gtgacagagg attttttcta
     7921 tagggcttta gcagctgcaa ttgcggcttc gaagtttggc tcagaattga tattatccac
     7981 gtattcaacg tagcgaatcg tattgtcagt atcgaggaca aagactgcgc gtgctaatag
     8041 gtgccattcg ttgatcaaga gggcataatc gcgcccgaaa gaatggtcaa agtagtctga
     8101 aagcataatg gcattgtcaa ggccttcagc accgcaccaa cgtttttgag caaaaggtag
     8161 gtccattgaa acagtcaata cgaccgtgtt gtccagtcca gccaattctt cattaaaacg
     8221 acgtgtttga gttgagcaga tacctgtatc gatagaagga acgacactca agactttttt
     8281 cttgccatca aaatcagcca gagatttttt agaaagatct gttgtagtaa gagaaaaatc
     8341 aagcgccttg tcgccgactt gtagttgttt acctgtaaag ctcacaggat ttccgagaaa
     8401 agttaccata ggatactcca atcttttttc ttccattgta tctaaaacag tcagaatttt
     8461 ccaatgattt gaccggaaat gtgtgcatag aaaaaacgcc agctcacatg agaatgacgt
     8521 ttttcagagg cttattttgc caatccttca gcaatcttgt caaggttgta tttcatcatg
     8581 ctgtagtagc tgtcgccttc tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg
     8641 tagattggga tgtttgtgtc ttgagaaaca gttttcattg gacggtcatc cacacttgat
     8701 tctacaaaga gtgatggaac ttttgtttgg cgaagttttt caaccaaggt cttgatttgt
     8761 tcaggagttc cttcttcttc agtattgatt tcccagatgt aggcacttgg gacaccatag
     8821 gctttagaga agtatttgaa tgctccttcg ctggttacaa tgagtttctt ttcagcaggg
     8881 atcttattaa atttatcctt actttcttta tcaagtttgt ctaacttatc agtatattct
     8941 ttgagatttt tttcatagaa ttctttattg ttagggtctt tggcgctcaa ttgtttggcg
     9001 atatttttag caaaaataat accgttttca aggttaagcc aagcgtgtgg gtcttctttt
     9061 cctttttcat tttgaccttc aaggtagata acatcaacgc cgtcgctgac tgcgaagtag
     9121 tctttgtttt cagttttctt ggcattttct accaattttg taaaccaagc attgccacct
     9181 gtttcaaggt tgataccgtt atagaaaatc aaatcagcct cagaagtttt cttaacgtct
     9241 tcaggaagtg gttcgtattc gtgtgggtct tgcccaatcg gaacgatact atgaaggtca
     9301 attttgtcac cagcaatatt tttagtaata tcagcgatga ttgagtttgt agcaacaact
     9361 tttagttttt gaccagaagt tgtatctttt tttccgctag cacatgctac aagaatgatt
     9421 gcagaaagaa agagaacgag taatgtacct aattttttca ttagatcctc caatttatta
     9481 gggctttgcc ccttatttta acaaatgttt atttttcagt ttcaaatatc gttgtttggg
     9541 agcgataaag aagctaatga gaaagaaact agcagctgta agcacgatac tagaacctgc
     9601 cgcaacatta aaactatagc caataaagag tcccaaaact gaagcagtag ctccgaaggt
     9661 tgaggaaagg aaaatcatac ttttcagact attagcatac agataagcag ttgcagctgg
     9721 ggtaatcagc atggctacaa tcaggatagt tccgacactt tgcatggctg tcacagacac
     9781 gagagtcagg agtaccatga gaaggtagtg atagaaattg acaggcattc ccatggcttt
     9841 agccaagagt tcatcaaagg aagttatcaa gagttgcttg aagaaaatcc agattaacaa
     9901 gaggatggct gcccccacac ccatagtaat aaacatatcc gtatcttgga cggccaggat
     9961 attaccaaaa aggatatgga aaaggtcagt tgaactttta gcgacaccaa tcaagatgat
    10021 accgagggct aagaaagaag aaaaggtaat gccgatggcg gtatcgcttt tgataatcga
    10081 gtttcctttg atgtaggtaa tgatgatggc agctagcaat ccaaagacaa tggctccgat
    10141 aaagaagtca aggcccaaga tgaaggagag ggctacacct ggtaagacag catgtgaaat
    10201 ggcatctccc atgagtgaca tcccgcgtag aataatgaaa catcccacag ctccagctac
    10261 aatcccgacg acaatagctg ttatcaaggc attttgtagg aaatggaatt tttgcaatcc
    10321 atcgataaat tctgcaatca taggtcacct ccattgaaaa agagttgatt accgtaagct
    10381 tcttttagat tggtttcggt aaaagtttct tttgttggac caaaggcaat cacttctcga
    10441 ttgacaagta agacttgatc gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg
    10501 agaaccgtct tcccagcttt tttcaaatct ctcagcgtat tcatgatgat ttcctcactg
    10561 acagagtcaa tcccagcaaa gggttcatcc aagaggatat agtcggcttc ctgcaccaaa
    10621 catctggcaa tcaagacccg ctggaattga cctccagaca gttgactaat ttgacgttca
    10681 gcgtagtcag ctaggccgac gatttcaagg gcctcttgca ctttcttcca atgtttagcc
    10741 tttaaacttc gaaagagagg aatagaggga aatagtccta acgagacgca ttccttgacc
    10801 ttgatgggaa agttgtagtc gatattgatt ttttgttcga cataggcaat tcggtgtaag
    10861 gattttttaa cttccttgtc atcgagaaat gcctgacctt gatgtgggat aattcccaac
    10921 atacctttta atagtgttga tttcccagcg ccgtttggac caatgatgcc ggtaattgtt
    10981 ggtccatgga gcactagtga aatatcctta agtgccaacg tttctttgta ggagacactg
    11041 aggttttcga tacgtatcat aaacttgtat tcctcctgtc tcttaatata cattaaaaaa
    11101 aaaattaagt caagttaatt tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa
    11161 agataacttt caggata
//
LOCUS       DAVMCN010000053        11014 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVMCN010000053 DAVMCN010000000
VERSION     DAVMCN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.054"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..596
                     /locus_tag="VYP85_001665"
     CDS             <1..596
                     /locus_tag="VYP85_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1882146.1"
                     /translation="YKDQEYKRNGYYTIDLFSPIYSALSGEKGTPGDLMGRRIAFELL
                     AAKGYKEGMVPYISNQYEKDAKAAGSKIKSYGKEVGLVTDKLVLEKVFNNRYSSWVEF
                     KKAMYNERIAKFNNLISVSFNNPNVSWGRTNRITITSIANLQNMINTAVNEDAEDFRA
                     QLYPDTNSRVLKLKKAIYKAYLDQTNDFRRSIFENKK"
     gene            640..5877
                     /locus_tag="VYP85_001666"
     CDS             640..5877
                     /locus_tag="VYP85_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1882147.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVSEDGERQIVT
                     SYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPVLTLTKVTEDAMNRSANLNY
                     ELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDWFKDYKIATTMIYDRG
                     QGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMY
                     LKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKP
                     HPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEG
                     KHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVT
                     GNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYV
                     DANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLS
                     HHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKE
                     HHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDL
                     AYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMV
                     HYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASV
                     QLISPGVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADH
                     QLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSV
                     DLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDW
                     FIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYN
                     TMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRV
                     PTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNP
                     NNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTP
                     SSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHV
                     EADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSS
                     INDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKH
                     NAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKY
                     WYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVF
                     KALLKNTDGFFNPLFKKDI"
     gene            6045..7391
                     /locus_tag="VYP85_001667"
     CDS             6045..7391
                     /locus_tag="VYP85_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1882148.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSCLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKERFFGDKMDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            7806..8657
                     /gene="ylqF"
                     /locus_tag="VYP85_001668"
     CDS             7806..8657
                     /gene="ylqF"
                     /locus_tag="VYP85_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1882149.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8644..9423
                     /locus_tag="VYP85_001669"
     CDS             8644..9423
                     /locus_tag="VYP85_001669"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1882150.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            9439..10989
                     /locus_tag="VYP85_001670"
     CDS             9439..10989
                     /locus_tag="VYP85_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1882151.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLRLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3641 a         1940 c         2262 g         3171 t
ORIGIN      
        1 ggtacaaaga ccaagaatat aagagaaatg gttattatac aattgattta ttttcaccga
       61 tttattcagc tcttagtgga gagaaaggga ctcctggtga tttaatggga cgtcgtatag
      121 cattcgaatt attagctgca aaaggatata aagagggcat ggtaccttat atctcaaatc
      181 aatatgaaaa agatgcaaaa gctgcgggaa gtaagattaa atcttatggt aaagaagtag
      241 gtttagttac agataaatta gtacttgaaa aggtatttaa taatcgttac tcatcttggg
      301 tagaatttaa aaaagcaatg tataatgagc gaatagctaa atttaataat ctaataagtg
      361 ttagctttaa taatccaaat gtaagttggg gaagaactaa tagaataaca ataactagca
      421 tagccaacct tcaaaatatg ataaatacgg ctgtcaatga agatgctgaa gattttagag
      481 cacaattata ccctgataca aatagtagag ttcttaaact gaaaaaagca atatataaag
      541 cctatcttga ccaaacaaat gattttagaa gatcaatttt tgagaataaa aaatagtgtt
      601 tactattagg aaataaaaag tgaatgtgga ggattagaat tgtcattatt aaaaaaagat
      661 aaattttcca ttaggaaaat aaagggtatt gttggttcga tattcttggg gagtttttta
      721 tttgcactgt cagttgttgg tgtatcgact tatcattact tagattatag tactttgaca
      781 caaactgaac gtgatcaact caaacaaggt agacctgatg aatcaaaaga gtcatatgct
      841 ttggtttatg aaaaagacgc attaccaaac acaggaagtt ctcaatctat tatgactgta
      901 ttgggtttgt tagctatcgg gagtcttatt gtgattatca caaaagataa aaagaggaaa
      961 aaaatagcta catttttgat tgtaggggcg acaggtttag ttacactatc aactgcttca
     1021 gcacttaatt tgaatgctaa catccatgag tctggacgtg atggtgtgtt gcaaatttct
     1081 ggttacagat atgttggtta cttggagctt gatgatagaa ctgtttcgtc ggtttctcca
     1141 gcatcaactg tttctccagt tgagcaaccc aaagttgtga ccgacaaagg cgaaccagaa
     1201 gttcagccag cgttaccaga agcagttgta actgaaaaag gggaaccaga agtacaacca
     1261 gccttacccg aagcagttgt aactgaaaaa ggggaaccag aagttcatga gaagcctgac
     1321 tatacgcaac caataggtgc aaaccttgtt gagcctgaag ttcatgagaa actagcatac
     1381 actgaacctg taggtacaac aggagtagat gaaaatggaa acttgattga gccacctgtt
     1441 aacgatattc cagagtatac tgaaccaata tctacagttt cagaagttgc atcagaaaga
     1501 gaagagttgc cttctttaca taccgatatt cgtacagaga ctattcctaa aaccactata
     1561 gaagaatctg atcctagcaa atttataggc gataattctg ttaaacaagt tagtgaggat
     1621 ggcgaacgtc aaattgttac tagctatgaa gagttacatg gcaaaaaaat cagcgagtca
     1681 gttgaaacag taacaatttt gaaagaaatg aagcctgaaa ttattgtaaa aggtacaaaa
     1741 gaaaaaacgg ctcctgtttt aaccttgacc aaagtaacag aagatgctat gaatcgttct
     1801 gccaacttaa attatgagct tgataataaa gataatgctg aaatatcaag tattgtagct
     1861 gaaattaaag atggtgatac agtagttaaa agggttgatt tatctaaaga aaaattaact
     1921 gacgctgtac aaaatttgga ttggtttaaa gattataaga ttgcaacaac aatgatttat
     1981 gatcgtggtc aaggttctga aacgtctaaa ctggatgaaa gacctctgcg tttggagttg
     2041 aaaaaggtcg aaattaaaaa tatcgcatct actaatttag tgaaggtaaa tgatgatggt
     2101 actgaaacac ctagtgattt tatgaatgaa aaaccttcag aagaagatgt taaaaaaatg
     2161 tacttaaaaa tcactagtcg cgataataag gtaactcgtt taactgtaga ctctattgaa
     2221 gaagtgactg aagaaggtca aaaactttac aaaataactg ctgaagcaca agatttgatt
     2281 caacacacag acccaacgaa ggttcgtaat aagtatgttt attatataga aaaaccccat
     2341 cctaaagaag ataatgtcta ctataacttt aaagatttag tagatgctat gaatactgat
     2401 aaaaatggta catttaaact tggtgcagat ttgaatgcca ctggtgttcc aacacctaag
     2461 aaatggtatg ttgacggcga ctttagaggt acattgaaga gtgtagaggg gaaacattat
     2521 actatccaca acacggagcg tccgttattc cagaatatta ttggtggtac agtaaccaaa
     2581 gtaaatctgg gaaatgtaaa tatcaatatg ccatgggcag accgcatcgc accgattgct
     2641 gacactatta aaggtggcgc taaaattgaa gatgtcaaag tgactggtaa cgtattaggt
     2701 agaaactggg tatctggatt tattgataag attgacaacc aaggtacact cagaaatgta
     2761 gcctttatcg gaaatgtgac atctgtaggt gatggtggtc aattcttgac cggtatcgtt
     2821 ggtgagaact ggaaaggact agtcgaacgt gcgtatgttg acgcaaatct tattggcaag
     2881 aaagccaagg ctgctggtat tgcttattgg acacaaaaca gtggtgacaa tcataaagtt
     2941 ggtgtcgaag gtgcagtcaa gaaaggaatt gtgaagggta ccattcaggt agaaagtcct
     3001 gttgaagtcg gcggtgctgt tggacgtttg agtcatcatg gttatatcgg ggaagtcgta
     3061 tctatgatga aagttaagaa gggtgaaatt ttttatggtt ctagtgatat gaatgatgac
     3121 ccatattggg tggcgaataa tgtacgagga aattatgtcg ttaatggtgt gagtgaaggt
     3181 acgatatctt atgctcgtgc taaagaacac catcgtatca aaccaatttc acagtcagaa
     3241 gcagatacta aaattatgat gttaggtatt acagcacaag attttgctat caacgaacct
     3301 gtggtcaatc gcttaaaccg tttaaccaga aaagaagatg aatataagtc aacccaagac
     3361 tataaagtag atcgagatct ggcttatcgt aatattgaga aacttcaacc attttataac
     3421 aaagaatgga ttgtcaacca aggtaacaaa cttgcagaag attcaaactt agctaagaaa
     3481 gaagtccttt ctgttacggg tatgaaggat ggacagtttg taactgactt atcagatatt
     3541 gataagatta tggttcacta tgctgatggt actaaagaag aaatggacgt cactaagaat
     3601 gctgattcta aagtgaaaca agttcgtgaa tataccatcg ctggacaaaa cgttgtttat
     3661 acaccaaata tggttgagaa agaccgtaac caattgattc aagatatcaa agataagttg
     3721 gcgtcagttc aattgatttc tcctggagta cgtgctttga tggatgcacg taagaaacca
     3781 gaagaaaata ctgatgaacg taagaatggt tatattaaag acctttactt agaagaaagc
     3841 tttgctgaaa cgaaagctaa tcttgataaa ttggttaaat ccttagttga aaatgcagat
     3901 catcaattaa atagtgacga aacggctatg aaagcacttg ttaagaaggt ggatgaaaat
     3961 aaagctaaaa tcatgatggc tctgacttat ctcaatcgtt actatgatat caagtatggg
     4021 gatatgacta tcaagaactt gatgatgttt aaacctgatt tctatggtaa atcagttgac
     4081 cttcttgatt tcttgattcg aattggatca agtgagagaa atatcaaagg tgacagaact
     4141 ttggatgctt atcgtgatat gattggtgga actattggta agtctgaatt acatggattc
     4201 ttagattaca atatgcgtct cttcactaac gatactgatt taaatgattg gttcatccat
     4261 gcagctaaga atgtatatgt atcagaacct caaacaacga acccagattt tgttaataaa
     4321 cgacatcgtg catttgatgg tttgaacaac ggtgttcata atcgtatgat tctacctcta
     4381 ttaactctta agaatgcaca tatgttcttg atttcaactt acaatacaat ggcttatagt
     4441 tcttttgaga aatatggtaa gtatacagaa gaagctagaa atgaattcaa aaaagaaatt
     4501 gataaggttg cacatgctca acaaacatac ttagacttct ggtcacgttt agcattgcca
     4561 agcgtacgtg accaattact caagagtgag aatagggtac caactcctgt gtgggataac
     4621 caaaactata gtggtattaa aggaataaac cgtatgggtt atgatgagaa gaaagtacca
     4681 attgcgccaa ttcgtgagtt atatggtcca acttggaaat tccataatac caactggaat
     4741 atgggagcta tggcatctat tttcccaaat cctaataaca atgaccaagt ttatttcatg
     4801 ggaacaaata tgattagtcc gtttggtatt tcagccttta ctcatgaaac tacacacgtt
     4861 aatgatagaa tgctttactt cggtggtcat agacaccgtc aaggtacaga cgtcgaagcc
     4921 tatgctcaag gtatgctaca aactccgtca agtattggtc accaaggtga atatggtgct
     4981 ttgggtttga acatggctta tcatcgtgaa aatgatggtg accaatggta taactatgac
     5041 cctgataagc ttcaaactcg tgaagatatc gatcgatata tgaaaaacta taatgaagca
     5101 ctgatgatgc tagatcatgt agaagcagac gccgtacttc cacaattgaa tggtgataat
     5161 agcaagtggt tcaagaaaat tgatagagaa atgcgcagaa atcttgggga tggtttgaat
     5221 aacttagtag caccgcacca atgggacaac gttcgtgact taaatcaaga agagagttct
     5281 aagaaattat caagtattaa cgatttgatt gataataatt tcatgaccaa acacggaaat
     5341 ccaggtaacg gacgttatag accagaggat tttagaccaa actcagctta cgtaaatgtc
     5401 aatatgatgg caggaattta cggtgggaat acgagtcaag gtgctcctgg ttcattatcg
     5461 ttcaaacata atgccttccg tatgtggggt tattatggat atgacaaagg tttcactagt
     5521 tatgtatcta gcaaatatca aggtgaagct gataaacaaa accagggtag attaggtgat
     5581 gatttcatta tcaaaaaagt ttcaaacaac caattctcaa atcttgaaga ttggaagaaa
     5641 tattggtatc atgatgtgaa atccagagct gaaaaaggat tcacagagat tacaattgat
     5701 ggacaaacca ttcacaacta taatgaactg aaagacttat tcgacaaagc tgtcacagaa
     5761 gacctcaaga aagctggaaa ctactcaaat actgagaatt tgaaatccaa agtcttcaaa
     5821 gctcttctta aaaacacaga cggtttcttt aatccattgt tcaaaaaaga catttaaacc
     5881 ccaattattc accccaaatc taaaaaccat ccagaatcct tgccttagct tagatcctgg
     5941 atggtttctt tttcacccaa tgggtgtttt ttactagaca aaaaagagtt tcccctttat
     6001 ggtataagtg tagaaaaaaa aacacaaaaa gaaaggaaac tcacatgaac agtttaccaa
     6061 atcatcactt ccaaaacaag tctttttacc aactatcttt cgatggaggt catttaaccc
     6121 agtatggtgg tcttatcttt tttcaggaac ttttttccca gttgaaacta aaagagcgga
     6181 tttctaagta tttagtaacg aatgaccaac gccgctactg tcgttattcg gattcagata
     6241 tccttgtcca gttcctcttt caactgttaa caggctatgg aacggactat gcttgtaaag
     6301 aattgtcagc tgatgcctac tttccaaaat tgttggaagg agggcagctt gcttcacagc
     6361 caaccttatc ccgttttctt tccagaactg acgaggaaac agtccatagt ttgcgatgcc
     6421 tcaaccttga attggtcgaa ttctttttac agtttcacca gctaaaccaa ctcattgtag
     6481 atatcgattc tacccatttc acaacttatg gcaagcaaga aggtgttgct tataacgccc
     6541 actatcgtgc tcatggctat catcctcttt acgctttcga ggggaagaca ggttattgtt
     6601 tcaatgccca gcttcgtcct ggtaatcgtt attgttctga agaggcagac agctttatca
     6661 cacctgtttt agaacggttt aatcaacttc tctttcgaat ggatagtggc tttgcgaccc
     6721 caaaattata cgatttaatt gaaaaaacag ggcaatacta cctcataaaa ctcaagaaaa
     6781 atactgttct gagctgtctt ggagaccttt ccctcccttg cccacaggat gaggacttaa
     6841 ccatcttgcc ccactccgcc tactcagaaa ctctctatca agcaggatct tggtcgcaca
     6901 agcgtcgtgt ctgccagttc tctgaacgaa aagaaggaaa cttgttctac gatgttattt
     6961 ctctcgttac aaatatgacg agtggaacaa gccaagacca gtttcagctt tatcgtggac
     7021 gtggtcaagc cgagaatttc atcaaggaga tgaaggagag attttttggc gataaaatgg
     7081 atagttcaac cttaatcaaa aacgaagttc gtatgatgat gagctgtatc gcctacaatc
     7141 tctatctttt tctcaaacat ctagctggag gtgacttcca aactttaaca atcaaacgct
     7201 tccgccatct ttttcttcac gtggtaggaa aatgtgttcg aacaggacgc aagcagctcc
     7261 tcaaattgtc tagtctctat gcctattccg aattgttttc agcactttat tctaggatta
     7321 gaaaagtcaa cctgaatctt cctgttcctt atgaaccacc tagaagaaaa gcgtcgttaa
     7381 tgatgcatta aagaacagtc gagatgaaaa aatcgtgtga cgtaccaagg gaggagtctg
     7441 cccttttgag gaaatctagc gaggaaaaac gatactggaa cagcagaaag taaaactgac
     7501 ctcatgagga catgaggtca ggggttttgt aagttacatc tagttgagag aggtatgaat
     7561 gatttgggtt aaatgtttaa aacataaaga ggacagtttt ttgctccctc tgaaaagtca
     7621 tcatttgatg gcttttttct atatagggta aaaggctatc atcggacaaa ataaagaagg
     7681 catgatataa tataaagtag atttttatgt cataaaacaa gaactgtttg gacatcattc
     7741 atttttagat tgagatctct tagttctaga ttaacagctt cagagctacg aaaggaaaaa
     7801 actcaatggc tactattcaa tggtttcctg gtcacatgtc taaagctcgt cgacaggtgc
     7861 aggagaattt aaaatttgtt gattttgtga cgattttagt agatgcacgc ttgcctctat
     7921 ctagtcaaaa tcctatgttg accaagattg ttggtgataa accaaaactc ttgattttaa
     7981 acaaggccga cttggctgat ccagcaatga ccaaggaatg gcgtcagtat tttgaatcac
     8041 aaggaatcca gacgctagct atcaactcca aagagcaagt gactgtaaaa gttgtaacag
     8101 atgcggccaa gaagctcatg gctgataaga ttgctcgcca gaaagaacgt gggattcaga
     8161 ttgaaacctt gcgtaccatg attatcggga ttccaaacgc tggtaaatca actctgatga
     8221 accgtttggc tggtaaaaag attgctgttg ttggaaacaa gccaggggtc acaaaaggtc
     8281 aacaatggct taaaaccaat aaagacctgg aaatcttgga tacaccgggg attctctggc
     8341 ctaagtttga ggatgaaact gttgcactta agttggcatt gactggagct atcaaagacc
     8401 agttgcttcc tatggatgag gttaccattt ttggtatcaa ttatttcaaa gaacattatc
     8461 cagaaaagct ggctgaacgc ttcaaacaaa tgaaaattga agaagaaccg tctgtgatta
     8521 ttatggatat gacccgcgcc ctcggtttcc gtgatgacta tgaccgtttt tacagtctct
     8581 tcgtgaagga agtccgtgat ggcaaactcg gtaactatac cttagataca ttggaagacc
     8641 tcgatggcaa cgattaaaga aatcaaagaa ctccttgtga cagtcaagga gttagaaagc
     8701 cctatttttt tagagcttga aaaggataat cgctcaggag ttcaaaagga aatcagcaag
     8761 cgtaaaagag ccatccaagc tgaattagat gaaaatttgc gcttggaatc catgctttct
     8821 tatgaaaaag aactttataa gcaaggattg accttaattg caggtattga tgaggttggt
     8881 cgtggtcctc ttgctggtcc tgtagtcgct gcggccgtta ttttacctaa aaattgtaag
     8941 attaaaggtc tcaacgacag caagaaaatt cctaaaaaga aacatctgga gattttccaa
     9001 gccgttcaag accaagcctt gtcgattgga attggtatca tagataatca ggtcatcgac
     9061 caagtcaaca tctatgaagc aaccaaacta gccatgcaag aagcaatctc ccagctcagc
     9121 cctcaaccag agcacctttt gattgatgcc atgaaactgg acttgcccat ttcacaaacc
     9181 tccattatca aaggagatgc caactccctc tctatcgcag cagcatctat agtagccaag
     9241 gtaacacgtg atgaattgat gaaagaatac gatcagcagt tccctggcta tgatttcgct
     9301 actaatgcag gatatggcac agctaaacat ctggaaggcc tcacaaaact aggagttacc
     9361 ccaattcacc gaaccagctt tgaacccgtt aaatcactgg ttttaggtaa aaaagaaagt
     9421 taattgaaag gaaataccat ggaggaacag tcggaaatag tccgttctaa gaaagaattc
     9481 gcctttgcat ccagcactat actatcccaa gttggtcgag gaatcattgt cggcctcatc
     9541 gttggaatta tcgtcggatc ctttcgtttc ttaattgaaa agggcttcca catgatacaa
     9601 ggagtttatc aagatcaagg gtacttagtg cgcaatcttt ttgtactggt tttgttttat
     9661 atactcatct gttggctcag tgccaaacta acacggtcag aaaaagatat taaaggctca
     9721 ggaattcctc aagtcgaagc cgaactgaaa ggcctcatgt ccctcaactg gtggggcatt
     9781 ctttggaaaa aatatgtgct aggtattctc gctattgcca gtggactcat gctgggtcga
     9841 gagggaccca gtattcaact tggagcagtt ggtggtaaag gaattgccaa gtggctcaaa
     9901 tccagtccag tagaggaacg ttccttgatt gccagtggag ctgcagcagg tttagccgca
     9961 gcctttaatg ctcctattgc agcacttctc tttgttgtag aagaagtcta tcaccatttt
    10021 tcgcgctttt tctgggtctc aactctagca gccagcatcg tagcaaactt tgtgtctcta
    10081 ctcatgttcg gtttgacacc agtattggat atgccagata acattcctcc catgacccta
    10141 gatcagtatt ggatatatct cgtcatggga attttccttg gattttcagg ctttctctat
    10201 gagaaagctg tattaaacgt tggaagagtt tatgacttga ttggtcaaaa aatccatttg
    10261 gatagagctt attatcccat cttggctttt atccttatca taccagtcgg aatcttctta
    10321 cctcaaatca ttggtggcgg aaatcagctt gtcctttctt taactgaaca aaattttagt
    10381 ttccaagttt tattagctta ctttttgatc cgctttattt ggagtatgat tagctatgga
    10441 agtggactgc caggaggaat tttcctcccc attttagctc ttggttcttt gcttggtgcc
    10501 ttaattggtg ttatctgtgt caatcttaga cttgtcagtc aagagcaatt ccctatattt
    10561 gtcattctag gaatgagtgg ctattttgga gccatatcaa aagctccctt aaccgctatg
    10621 atcctcgtaa ctgagatggt aggagatatt cgcaacctca tgccacttgg tcttgtcact
    10681 cttgtttctt atattatcat ggatttgctc aaaggtacgc cagtctatga agccatgctg
    10741 gaaaaaatgc ttccagaaga agtatctagc gaaggagaag ttacacttat cgaaatacca
    10801 gtttctgata aaattgctgg gaaacaagtt catgaactca acttaccaca caacgtcctc
    10861 atcacaactc aagtccataa tggcaagagc caaacagtta acggctcaac cagaatgtat
    10921 ctgggtgata tgattcacct ggttattcca aaaagtgaaa ttggaaaagt caaagatttg
    10981 ttgttgtagt acaatcattt acataattta tatt
//
LOCUS       DAVMCN010000054        10782 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVMCN010000054 DAVMCN010000000
VERSION     DAVMCN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.055"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            50..214
                     /locus_tag="VYP85_001671"
     CDS             50..214
                     /locus_tag="VYP85_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1882152.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            298..864
                     /gene="amaP"
                     /locus_tag="VYP85_001672"
     CDS             298..864
                     /gene="amaP"
                     /locus_tag="VYP85_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1882153.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            876..1046
                     /locus_tag="VYP85_001673"
     CDS             876..1046
                     /locus_tag="VYP85_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1882154.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1085..1693
                     /locus_tag="VYP85_001674"
     CDS             1085..1693
                     /locus_tag="VYP85_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1882155.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1724..1927
                     /locus_tag="VYP85_001675"
     CDS             1724..1927
                     /locus_tag="VYP85_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1882156.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2037..2309)
                     /locus_tag="VYP85_001676"
                     /pseudo
     CDS             complement(2037..2309)
                     /locus_tag="VYP85_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2513..2800
                     /locus_tag="VYP85_001677"
     CDS             2513..2800
                     /locus_tag="VYP85_001677"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1882157.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3078..3848)
                     /locus_tag="VYP85_001678"
     CDS             complement(3078..3848)
                     /locus_tag="VYP85_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1882158.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3863..4711)
                     /locus_tag="VYP85_001679"
     CDS             complement(3863..4711)
                     /locus_tag="VYP85_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV1882159.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4708..6183)
                     /locus_tag="VYP85_001680"
     CDS             complement(4708..6183)
                     /locus_tag="VYP85_001680"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1882160.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHTLGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6507..7862)
                     /locus_tag="VYP85_001681"
     CDS             complement(6507..7862)
                     /locus_tag="VYP85_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1882161.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNYLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7872..8189)
                     /locus_tag="VYP85_001682"
     CDS             complement(7872..8189)
                     /locus_tag="VYP85_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1882162.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8206..8523)
                     /locus_tag="VYP85_001683"
     CDS             complement(8206..8523)
                     /locus_tag="VYP85_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1882163.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8538..9434)
                     /locus_tag="VYP85_001684"
     CDS             complement(8538..9434)
                     /locus_tag="VYP85_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1882164.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9437..10699)
                     /locus_tag="VYP85_001685"
     CDS             complement(9437..10699)
                     /locus_tag="VYP85_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1882165.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3708 a         2182 c         1661 g         3231 t
ORIGIN      
        1 gaggtcttat tggtctcttg gcaggtaaaa tcactaaaaa agtagttcta tgggaatcat
       61 cgcaaatgta ttcgctggtt tagtcggggc atatgcagga caatctcttt taggtagttg
      121 gggtccatca atcgctggaa tggctttgct cccatctatt gtaggtgcag cgattgtgat
      181 tactgtagtg tcattcttta caggtagaaa gtaaactttt cgccagtaaa gttagcaaac
      241 tatttttaaa tcaatgacgg gaaaaatagt ttaaatgtta aatcgaaagg attgtatatg
      301 tcaaaagcaa agaaaatatg tttcattatt ttctgtattt taatcttgac aattttcctt
      361 cctgttttga tagattatca tcaagttagt gatctaggta ttcatctact tagctggaga
      421 cagaactccg tagttgaatt ctatcttgct agatatgtct tttgggggac agtggttcta
      481 tcaactttag ttttattatc cattttagtt gtgatgtttt atcctaaacg ttacttggaa
      541 atccaacttg aaactaaaaa cgatacatta aaattaaaga attcggcaat cgaaggtttt
      601 gttagaagtt tggtgagtga tcatagattg atcaagaacc caactgttca tgtaaattta
      661 cgaaaaaata aatgtttcgt tcatgtagaa ggtaaaattc ttccttcaga caacatcgct
      721 gacagatgcc aaataattca aaatgaaata actaatggat tgaagcagtt ttttggtatt
      781 gagcgtcaag taaaacttga agttgcagta aaaaattacc aaccaaaacc tcaaaacaaa
      841 aagactgtta gtcgtgtgaa gtaaggaagt aaaaaatgga atggcttaaa caatatcgat
      901 atccaattat cgctggtctc ataggcgtat ttctggcttg tttgattgtc tcctttggct
      961 tcttcaaaac aatatttgta ttgattttag gagcactggg agttgcagct ggattatata
     1021 tcgaaaaaaa ctatatagat aaataaaaaa ataaaaatta ctaatttaat taaaggagtt
     1081 tcatatgtca aacgaaaaaa acacaaatac taacgtagaa aagaaagatg ctactgttgt
     1141 agctcacgaa atcaaagggg aacttactta cgaagataaa gttatccaaa aaatcattgg
     1201 tctttcacta gaaaacgttt caggtctttt gggaatcgat ggtggtttct tctcaaatct
     1261 taaagaaaaa atcgttaaca gcgatgacgt aacaagtggt gttaacgtag aagttggtaa
     1321 aacacaagtt gcagttgact taaacgttat tgttgagtac caaaaaaatg ttccagcttt
     1381 atattcagaa atcagagaaa tcgtatcttc agaagttgct aaaatgactg acttggaaat
     1441 tgttgaaatc aacgtaaacg ttgtcgacat caaaactaaa gaacagcatg aagcagactc
     1501 agtaagcctt caagatcgcg tatctgacgt tgctgaatca acaggagaat tcacttcaga
     1561 acaattcgaa aaagctaaat ctggtcttgg atctggtttc tcaactgttc aagaaaaagt
     1621 tagcgaaggt gtagaagctg ttaaaggggc agcaaatggt gtagtatctc acgaaaacac
     1681 tcgtgtaaac taagataaaa taaatataac aggagaaatt atcatgtcag tagaagaaaa
     1741 attaaatcaa gctaaaggtt ctattaaaga aggtgttgga aaagccatcg gtgatgaaaa
     1801 aatggaaaaa gaaggagcgg ctgaaaaagt tgtttctaaa gttaaagaag ttgccgaaga
     1861 cgctaaagac gctgtagaag gtgctgtaga aggtgttaaa aacatgttga gtggcgacga
     1921 taaataaggt taaaagttac tttatctttt tggtaacatt agtcaaaaga gtctgagtcg
     1981 agatgattct cagaaaacaa aaagctagag attcccaatt gcggaactct agctttttaa
     2041 ttttgcctct ttctcttatt atatttcagc aggttgttgg ccatgagtat gaatcccatg
     2101 tcaattctca cttgacgctt acctctcaga tgacatctct tataacccaa acaaaccttt
     2161 atctgcccaa agacagattt catatcaatc ttacgtttag cgaaaatttg tctacccttg
     2221 gaagataaaa gtgcctgata ttctttagtt tttaaacact ggtaacgttc attcatatac
     2281 agtctctttt gaggggctga ttcaggttca taatcgcagt caacattgat ttcaaggctg
     2341 tttgctttct atctcccctt tttcatgata tattttcgta caggtgcttc aatagtttct
     2401 atagtaaaat gaaccaaaaa tagtacacgt tgcggtataa tgttcttatg gcatattcat
     2461 tagattttcg taaaaagttc tctcctattt gtgagcgaac aggtatagtc aattgattgt
     2521 cagtttgaag accaagagtc gtaaggcaaa ggatatggca gaatccatcc aagggtggct
     2581 ggcacaattt ctagtgaacc tctttaaatc tattacgttt gactgtggaa aagagttttc
     2641 aaaatggaaa gatatttcca atcatcacga tagtgagagc ttttttgcga atctaggatg
     2701 tccaagacag cggtgtctca acgaacattc aaatagactt ttaaggtgtc atgacttgcc
     2761 aaagcagaca gatttcaacg aagtcagtca agaattttag gctgggtaaa aactcaattt
     2821 caggagaaaa tgaaataaat attcccacaa taaaatgcat agtatcaaag tttttccaac
     2881 acctgatatt atgcattttt taattttaaa gactttttcc cagcctcaag aaatcacatc
     2941 ccacctaaat cctttggata ccaaatacct catcaggtat tttctgagtt ggtaagactg
     3001 tctagcttaa tttgacaaat ggagggcgtt aaatccagtt tttacaggaa gtctatttaa
     3061 atattttcac actgacctta caaaatatga aataaattat ataaagtcat tcccatgaca
     3121 aagaataaca tccctttaaa acagtatctt acccaatttt caggtaagac ttttgataca
     3181 accgtcccca atacccctcc gcatatagaa gcaagaaaaa taactggaac aggtgctaaa
     3241 tgatactgat ttaaacctgt aaccacaaca attgtagcca aatgagacaa ctgggaaaag
     3301 aaaataattg caagagaata catcgttgct tcttttatcg aaatagaaaa aaacaccatc
     3361 aataaagata cattgagcgg accaccacca atccctaaaa aactagaaat caagcccaat
     3421 agaagaccac aaatcatata gaatcctatc ttatcaaatt gataagtttt tttaaaatct
     3481 gttaaaacaa atgatacaag tagcatcaca aatagtaaaa tcatttgaac aatggatact
     3541 agccgtactg ataattgaga taacaaaact tgaaaaataa gatgacctag aaaccctcct
     3601 aaaacagaag aaaaggatac cgtaaaaatc aatctccatt ttatctcttt actttgtgaa
     3661 aatcttttgg ttgttgaaat aatcgccatt ataaaaacag agaaactaga ataaaaagca
     3721 atatcactga ccgaatggta tccaaaacta tccataagtg gcttaattat aattccacca
     3781 cccatgcctg atatagaacc caatccacta gctattataa tgattagaaa ataaataatc
     3841 tcaaccactt tttaagtcca tcctattctt tcaaacatct aaaacctaga tggctactag
     3901 tggaagtaga aatacatcca tttctagcag ctactcggta tcgattacaa taagaacaat
     3961 gacataaaaa ggaacctcct ctgatagcat actcctcatc ttgtatccca tattttggta
     4021 actcatagtc atcttcatta aaactagcta ataaggtata tctcggattg cgacaccatt
     4081 cccaaacatt cccaatcatt tgatatagac caaaatcatt aggtaaaaat tcatagacag
     4141 gagccgttcc tataaatcca tctaaggcag tattttcata aggaaatctt ccttgccaag
     4201 tattggcatg ataatatcca ccttctaaaa gagtatctcc ccaaggatat tcagattgtc
     4261 ttcctcctct agcagcatat tcccactgtg cttcagtcgg taaagacatt ccgctccaat
     4321 tacagaaagc caatgcatct tctaaagcaa catgaactac tggatggtct tctaaaccca
     4381 ctagattact gttctcaccg tagggatgtt tccagcaagc gttcgaaact tgtaaccacc
     4441 acggagcccc agcaggatga ggatatccct ccctttctgc ctccggaacg aacaatataa
     4501 aaacaaaaga ccactcttgt cgctcagcta gtgttttata gcctgtttct ttcacaaatt
     4561 gagcaaattc ttgattcgta actggagtat ccgcaatgga aaaatccttt acactaacag
     4621 cgacttgagg accttcaaaa tcatctaaaa agccctcttc agaatttgtt cccatcataa
     4681 atgtcccacc cttgattttt ttcattttca tgattgacta tcccccgttt tcgttagagt
     4741 tggcgttatt ttagaaagtt caacaggaac taactcttca tccacaacaa aaccttcttc
     4801 tctatatcta agaaagtcta ctaatttttt cttcatctga cgaacaatag gttgatattt
     4861 ttcacttgga tacaaatcat tcatttcatg cggatctttt ttcatatcaa ataactgata
     4921 atgatttaaa acaggaaacc agataaattt ccactggtct gtcaaaatat attgactaga
     4981 atcttttcct aaagtatgtt caccatgaaa ttctgttcgc cacccctcgt actgtccaaa
     5041 taataaattc ttaacactcc gtccatctag ttcatctgta gtagttcctc ctgccaaatc
     5101 cacgagtgaa ggaaaaatat cttgaatttt cactaattgc ttgattgttc ccctattacc
     5161 agctatcaat ccagccggat cgtaaataaa cgaaggaatg tggatacttc cctgataagg
     5221 atatcccttt ctaaacagat aatgttcacc aagctgatct ccatgatccg aaacaaacca
     5281 gataatcgta tctttatcat gacgaaattc ttttagggca gtcaaaaagc gactaatttg
     5341 atggtctata tgagtaatca atccaaaata agcagcaacc attcttcttt gatcatcttc
     5401 ctttaatttc cctcttaaag cataaataga cggaatttgc ttttctaata cttcccaatt
     5461 cccgatatgc aaatcgagaa attgaggcaa gcgttccata tacatatcaa aatagtattt
     5521 tgggggattt aatggagcat gtggtttttc aaaagacatt ttgagaaaaa aaggaaccgt
     5581 tggatctctt ctttgtaaaa atgaaatgga ctcactcaca acccagtttg ttggatgtaa
     5641 cttctcatct ttatcccaag gtctagcttc ccaagaatta caatccattc cgtcatcaat
     5701 caaatcaaca tcataaccaa ctttaccctt taaaaaggct agatagtcac tagcataatc
     5761 aaattgactt ccataagcct tatcatactt tctatcaaca tgtagatacc catcgtgaag
     5821 taagacatga tcaaacccaa gtctctgtct ggaaggaaaa acatgcatct taccaataca
     5881 ctctgtttga taacccatat ctttaaagac ttttggaaga gtattagtaa aattccaagg
     5941 cacctcatct tgataaccaa ctcgtccact tttatcttgg tctaagccag tcaataaagc
     6001 tgccctagca ggaacgcaag aaggaactgg agaataggca ttttcaaaat tataacctac
     6061 actagccatc atatctaatg ttggagtgct aactagctta tccttactat tcaaggataa
     6121 ggcgtctgct ctcatttgat ctacaacaat caaaataata tttggctgtt ttgtctgaac
     6181 cataaaatct cctttctaat atggcaaaag aggcacaaga agatatctac ctttactgca
     6241 cccctttcta tatcaatctc tctatataaa acaataacat tcttgttatg ttttatagaa
     6301 aaatgaacta aaatatgact aaatcgatta ggaaattcaa atcattttct agtactattt
     6361 tagaagttac agtgtactat tccaacttca ataaactata aacctttgtc taataacaat
     6421 tttagtggag ataagaaatc ctacacctaa ctcaatctta cacgtaatct atttctattt
     6481 tatcacaaaa aacgcaagta agaccattaa ctcaattcag ttttatctgc cattttcaca
     6541 aatgggaaat aagtcaagac actaataatc aaacaaacaa ctgataagat gatggcacgc
     6601 caatcaaatg ctgtagagaa gaaaccatat aaaattggag gcattaccca agtaacattt
     6661 tgtgtaacag gtgaaacaag accccagctt gttgcccagt aagctaccgt tgccatgaaa
     6721 accgggctaa gtacaaatgg tataaatagc aaaggattca agacaactgg taaaccataa
     6781 tttaccggct caccaatatt aaacagaact ggtgctagac caagtttagc aacttttcga
     6841 taatgactgt ttcttgaaaa aattaaaata gcaagtacca atcctaatcc tccaaaccag
     6901 acaaacgccc caaaagaccc acttgtccat atataaggaa tcggttcacc tttttggaaa
     6961 gcatccagat tcgctaacat agcaactcca aacagccctt ccatgatggg agccaataca
     7021 tttcctccat ggagaccaaa aaaccagaat aacttattta aaaagatcat cagaataact
     7081 gcaaagaaac tttgagacaa acctagtaat ggcgtttgta acaccttgta aacccaatca
     7141 atcaataagt aattgctaag taaatggaaa acataagtca agatggctac tatatacatc
     7201 gccataaatc ctggaatgat agaagtgaac ggcttagcaa tcgcaggggg aactgaatct
     7261 ggtaacttga ttacccagtt ctttttcatt actttacaga aaataataga ggctaaaaat
     7321 ccaatcatca tggctgtaaa gtagcctctg gcattaatat ggtttcctgg aatcacattc
     7381 ccaatagtta ccatcagatt tttaccatca aatgctagat tatcaattcc ttgtaagatt
     7441 tgatctaatt tcacatctcc tacatttgcc aaagggaaac tctttgtaac tgtacttcca
     7501 atcgaaatga caaacgaagc aagcgatacc aaaccagcag aaactgtatc aaccttataa
     7561 atcttagcga tattcactcc caagcaatag atgaacaata aggaaacaat tggtatactt
     7621 cccttgaata ccaaattatt gatgtcaaca agccactgaa aggttttcgt aatactttct
     7681 aggtgaaatt gttgtggtaa atccactaga aaagcattta ataacaaagc aatggaacct
     7741 gtcataataa caggcatagt ccccacaaat gaatcacgta aagcaactaa aaacttctga
     7801 ttcccaactt tcattgcaat tggagaaagt ttttcttgca ttttatccaa cattgtattc
     7861 atagcaaatt cctaattttt ttcaaatcgt tcgtatactt ctaccacttc tttcgccaag
     7921 tcaacaaagg tcagactcgt cattaaatga tcttgcgcgt gtaccatcaa gaggctaatt
     7981 gatgtttctt ccccctgtgc ctctcttgtc aacatttctg tttgagcctt atgcgcctgt
     8041 aataaggcag cattcgcatc agctaatctt cgattggctt tagagaaatc cccttttttt
     8101 gctgcctgaa tagcctccat agcattactt ttggcttccc caccatacat aattagcccc
     8161 attacagatt ctaaattact ttcatccata acattctcct caatcttagt ctaataaact
     8221 ttcagctaaa tctaagactt tagaaccatt catcattcca taatctgtca tcggaataac
     8281 cgccacagga atctgtctat cttttagttt ttcttgaaag tcccctagta aatagcgaac
     8341 ttgaggacct aaaagcaaca catttacttc ttttgttgct acaatttctt ctgcttcagg
     8401 agctggaact gcaaaaattt ctgcatccaa ccccttatct tctgctgcct tttgcatctt
     8461 tgtcactagc agacttgtac tcatacctgc tgcacatgct aacataattg ttactttagc
     8521 catagcttac tcctttatca cctatttact gacctagcca agcgagatac tgtatgtctc
     8581 actcctctaa ttgccttgct caatgcataa atattatcga ctgttgccag tcccccatat
     8641 cctgcgtcac ctatatgttg aatatcaact ccacaaattt tatttctaag tgcaatttcc
     8701 ttaatagtat ctgtatcaga tgtttcttgg ctagtaccaa tagcactcaa tacaagacca
     8761 cccttactat gaacgagatc aacgacttca cgcaactctt ggtcatgaaa ggctggaacg
     8821 gttccaactg ctggaacaag tatcacatcc gcacctgctt ccaacaattg ctctgcgaca
     8881 gaaagctctg ccacaggctc attcactcct gccccgtgca tcttacctgc aataatcaaa
     8941 ccagaaaagt tttccttagc agtttgaaca gccttaatga tttctcgatt gctaactcct
     9001 gttccaggat ttccagtcaa acagacaaag tcaaaaccta actcctctat tcgcttcaat
     9061 gtttcaacac tagcaacacg acctgcaaca atttcctgtg tttcctctag catctttgca
     9121 gatgggtcaa tcggttccaa atttacacca attgggcaag caacgagctg gtgtaagcga
     9181 tgaataacat catcacctga actatccaaa gcataaattt taggctcaaa aacatcaaca
     9241 caattcaata aaatcatatc agctccaaaa gctctagcaa tttcagaatt agttatatcc
     9301 ccaacaaatg tctcacgagt gactacattt tcagatagaa caactctacc ttcacttgct
     9361 aaaatacttt gttttaattc ttcagcattc atctgtaata tctcagatgg atttgcacta
     9421 attaaacgtt tcattctcaa tcctccaata acttaaaccg tttttcaata gctattacaa
     9481 atggtaaata aagtaagaca tccaaaacaa tcaatacaat ttgtaataat gaaccagaaa
     9541 tacttcctgt agcaagtaaa ccacttataa caggtggcat agtccaacct ggatctgtat
     9601 aagttagcgg aaccaagcct gatgccattg ctccccacgc tactagtaag ttaaacattg
     9661 gagctaagat aaatggaact agtaacaaaa tgttcaaaac aataggaaca ccaaacattg
     9721 ctggttcatt tatattaaat aatccaggta taacagttat aggtgccaaa gtttttagtt
     9781 gtttactagc tttcttctta tgtgctaaat atcctaacgc aagaactaaa cctatggttg
     9841 caccaccgcc acctatgaat acaaaattat ccataaatac gctagtaaaa atatttggaa
     9901 gagtttctcc agtttgataa gctactttat ttgcatctag attagctaac cataacggtt
     9961 tcataactgc attaacaaca tttcctccgt gtaatcctac aaaccaaaaa ctactattaa
    10021 ggaaaattaa gataagaaga ccaataacat tatttcctaa aagtccaagt ggacctccca
    10081 aagctacttg agcaatttca tgaagattag gtaaacttaa tttatctaaa gttgcataaa
    10141 caatcaacca accaacaata gtcactgcac caggaataat ggcactaaag cttttagata
    10201 ctgctggtgg aacaccatcc ggcattttta tctgtatatt atgatttata aaccattggt
    10261 agatatagcc attaatcaat cctaaaatca tagcaacaaa taaacctttt gatgccatga
    10321 aagcggtagg cattcctgct ccagcctctc ctctaatgaa aggcgtaact gtaataaaag
    10381 atgataatga cacaatacca gcaggaatac catcaacttt gtattgtcta gccataaagt
    10441 aagcgatacc aaaactagct acaagaccaa gtaatccaaa actactatca acacccttcc
    10501 ataaatagtc agcaacacca atatcaccca gatatttttc ccatcctgga ataggaaaac
    10561 ttgcaataac cattagtaat gaacctatca acaataaagg tatagttaga gtaataccgt
    10621 ctcgaataga aaccaacgct ttattattac ccaatctagc cgctactgga agtaactttt
    10681 cttgtaataa tttttccata accttttcct cttaaatata ttttattatc aaaagttatc
    10741 aattatcttt attttttgac gtcaagttgt tatttgatta tc
//
LOCUS       DAVMCN010000055        10752 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVMCN010000055 DAVMCN010000000
VERSION     DAVMCN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.056"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            189..686
                     /locus_tag="VYP85_001686"
     CDS             189..686
                     /locus_tag="VYP85_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1882166.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            686..2341
                     /gene="dnaX"
                     /locus_tag="VYP85_001687"
     CDS             686..2341
                     /gene="dnaX"
                     /locus_tag="VYP85_001687"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1882167.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYTPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQIEKEVEESLIPEGFEFLADKVKVEED"
     gene            2369..2563
                     /locus_tag="VYP85_001688"
     CDS             2369..2563
                     /locus_tag="VYP85_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1882168.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2713..3483
                     /gene="sufC"
                     /locus_tag="VYP85_001689"
     CDS             2713..3483
                     /gene="sufC"
                     /locus_tag="VYP85_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1882169.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3511..4773
                     /gene="sufD"
                     /locus_tag="VYP85_001690"
     CDS             3511..4773
                     /gene="sufD"
                     /locus_tag="VYP85_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1882170.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLLGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4784..6010
                     /locus_tag="VYP85_001691"
     CDS             4784..6010
                     /locus_tag="VYP85_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1882171.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINACSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5997..6437
                     /locus_tag="VYP85_001692"
     CDS             5997..6437
                     /locus_tag="VYP85_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1882172.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6487..7899
                     /gene="sufB"
                     /locus_tag="VYP85_001693"
     CDS             6487..7899
                     /gene="sufB"
                     /locus_tag="VYP85_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1882173.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKDGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8098..9339)
                     /locus_tag="VYP85_001694"
     CDS             complement(8098..9339)
                     /locus_tag="VYP85_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1882174.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9442..10551
                     /locus_tag="VYP85_001695"
     CDS             9442..10551
                     /locus_tag="VYP85_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1882175.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3181 a         1970 c         2335 g         3266 t
ORIGIN      
        1 tctttctaat gagttgtttg atcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaaatag gctccataat atccataggg gatttaccca ctacaaatat tatagagccc
      121 aaaatccttt gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata
      181 atagttctat gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt
      241 ccttcctatt ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctca
      301 taaaatcacg ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat
      361 tggttttagg tcccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg
      421 tttgtggtga ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc
      481 tcaactatat ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga
      541 atggtcagtt acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta
      601 tggatcgaga ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact
      661 ttacgatgtt tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca
      721 aaacttctcc cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga
      781 gcaagagaaa ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag
      841 tgttgctaaa atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg
      901 caataactgc tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat
      961 ggatgcagct tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta
     1021 tacgcctagc cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac
     1081 aggggctttt aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat
     1141 tttggccact actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt
     1201 tgagtttaaa tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa
     1261 agaaaatatc agttctgaac cagaggctgt ggaaatcatt gccagacggg cggaaggtgg
     1321 aatgcgggac gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct
     1381 gacgactgct atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta
     1441 tgtggcggcc ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt
     1501 tgacaatggt aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt
     1561 gttaattgtt caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt
     1621 ggcacttcct caaaaaaatc tgtttgaaat gattcgctta gcaacagtga gtttagcaga
     1681 tattaagtct agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga
     1741 aatcaagccc gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca
     1801 ggaagttgcc cgtctcaaac aagagctttc taatgtaggt gcggttccta aacaagttgc
     1861 accagctcct agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt
     1921 gcaatctatc ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg
     1981 tttgcagaat gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct
     2041 agttggttct caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa
     2101 cttcaatgct ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct
     2161 cagtcaggcg gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga
     2221 agttcgcgca gccttttcag ccaaagccaa atcttctcaa attgaaaaag aagtagaaga
     2281 aagcctgatt ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta
     2341 aagaaagatt tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct
     2401 gtttacagct gctgagacct attttttcaa tgaagcctgg atgactggtc gctatattat
     2461 ggcagccttt tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggcaa
     2521 aatcgttgat gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca
     2581 aaatcaaagc cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt
     2641 gctctatttc tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag
     2701 aaaggaacta tcatgtcagt attagagatc aaagatcttc acgttgagat tgaaggaaaa
     2761 gaaattttaa aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga
     2821 ccaaatggta caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa
     2881 gtaactaaag gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag
     2941 cgtgcgcgta tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc
     3001 aatgctgagt ttcttcgtgc cgctatgaat gcgggtaaag aagatgatga gaagatttca
     3061 gttcgtgagt ttattactaa gctagatgaa aaaatggaat tgctcaacat gaaagaagaa
     3121 atggcagagc gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt
     3181 cttcaacttt tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt
     3241 gatattgacg ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt
     3301 ggtgctatga tcatcactca ctaccaacgt cttttgaact atatcacacc tgatgtggta
     3361 cacgtgatga tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg
     3421 gaacgtgaag gatacgcaaa actagctgaa gaacttggct acgactacaa ggaagaattg
     3481 taattccctc gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca
     3541 gaaatgcacg ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt
     3601 gagactttgg aattaccagt tattgagcgt gtcaaattcc accgttggaa tctgggtgat
     3661 ggaacgatta cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat
     3721 cacttgaagt tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta
     3781 gctgaacagg gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg
     3841 atcgaagaat tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac
     3901 acagcttact ttaacagtgg tgctgtactc tatattccag ataacgtaga aattacagag
     3961 ccaattgaag gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt
     4021 atgattatcg ctggtaaaaa ttctaagatt agttatctgg agcgtttaga gtcacgcggt
     4081 gaaggaagtg acaaagcaac tgccaatatc acagtggaag tgattgcacg ttctggtgcg
     4141 caagtcaagt ttgctgctat cgaccgtcta ggtgaaaacg tcactgccta cattagccgt
     4201 cgtggtaaat taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga
     4261 aatgtcgttg ctgattttga tagtgacttg cttggaaatg gtagccatgc ggacctcaag
     4321 gtagtagcac tttcaagtgg tcgtcaggtg caagggattg atactcgcgt gactaactat
     4381 ggttgcaact ctatcggaaa tatcctacaa catggggtta tccttgaaaa agcaactttg
     4441 actttcaatg gtatcggcca catcatcaag ggtgctaagg gagcagatgc ccaacaagag
     4501 agccgtgttc tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt
     4561 gatgaaaatg atgtcactgc aggacacgca gcgtctatcg gacaagttga tccagaagac
     4621 atgtattacc tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt
     4681 ggtttccttg gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt
     4741 gcaactatcg aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc
     4801 gattcgcaag gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct
     4861 ggacaatgct gcgacgacac aaaaaccact agtagttctg aaagctatta acagctacta
     4921 tgaacaggac aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc
     4981 ttcttatgaa gctgctcgtg aaaccattcg taagtttatt aatgcatgct ctacaaagga
     5041 agttctcttt accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga
     5101 aattctcact gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat
     5161 tccatggcag gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga
     5221 cggtgccttg gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc
     5281 cctagctcat gcctccaatg ttcttggtgt ggtcaatccg attaaggaaa tcactcaatt
     5341 agcccaccaa gttggggcaa tcatggtagt ggatggtgct caatctacac ctcatatgaa
     5401 gattgatgtc caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg
     5461 tccgactggt atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt
     5521 agaatttggc ggcgagatga ttgattttgt ctacgagcaa tccgctagtt ggaaggaatt
     5581 gccttggaaa tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc
     5641 agttgattat ctggaaaaga ttggtatgga tgccgttgaa gctcatgaac aggaattgat
     5701 tgcgtacgtc tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga
     5761 tttggctcaa cgttcgggtg ttattgcctt taacctaggt gatctccatc ctcacgatct
     5821 tgcgacggct ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc
     5881 cttgcttcag tatttggaag tcccagcatc agctcgtgca agtttttata tctataatac
     5941 caaggcagat tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg
     6001 cactttctaa actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac
     6061 atcaccaagg gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtgggg
     6121 atgtcatcaa cctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc
     6181 taaattcagg atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag
     6241 gaaaaaccaa acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc
     6301 aaaaagatga gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat
     6361 tccctcaaag aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa
     6421 atcaagaaaa acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag
     6481 gatattatgg ctgaagaaag agtagaacca aaaccaattg accttggtga atataaattt
     6541 ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa cgaaggtgtt
     6601 attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt ccgtttgaag
     6661 tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt gtcagagatt
     6721 gactttgatg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg ttcttgggat
     6781 gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga agctgaacgt
     6841 gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca caacatgaag
     6901 gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact caaggaatac
     6961 ccagacttat ttaaacaata ctttgcgaag ttggtaccgc cgacagataa caagttggca
     7021 gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa aggtgtcaag
     7081 gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg tcagttcgaa
     7141 cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg atgtacagca
     7201 ccaacatatt caagcaatag cttgcacgct gccattgtag aaatttttgc tttggacgga
     7261 gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa cttggtaaca
     7321 aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa cttgggtgcc
     7381 aaaacgacta tgaaatatcc atctgtttat cttgatggag aaggagcgcg tggtaccatg
     7441 ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa gatgattcac
     7501 aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaaga tggaggaaag
     7561 gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt ttcccatatt
     7621 gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc atttaatgaa
     7681 attcacaact cgcaagtggc tttggaacac gaagccaaag tatctaagat ttcagaagag
     7741 caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga aatgattgtc
     7801 atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt tgagctgaac
     7861 cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt atactcttcg
     7921 aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact gacttcgtca
     7981 gtttcatcta caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgt
     8041 tctttgattt tgaagatgaa cttgtatcaa aaaatcgcgg tttaaaatcg cgatttttta
     8101 taatttctcg ttaacaaagc ggacaaactg attccaccaa acttttaaga agaaggcttt
     8161 ttcaattttc ttgtctgcta ccatttcgaa actagggcgc tctgtggtga tgtaaccttg
     8221 accaatcaag tccttgtctt cataagtcaa atggccaacc actgttccag cttcaagtgg
     8281 tgctgggatt gctttggaat caggtgtgaa ttgaacagat tgggaagatt gattcccaac
     8341 acgttctatt agatagatat cctctggagc cactgcagtt actgtatctt cttttccatc
     8401 ttgtacaggg gttttgctat cttgataggc atcgccttgt tgaacgattt tgcgaagtgt
     8461 aaatgtagaa gaaatataat ccattaggga agatgtagct gtaaatcgag cgtaaggatt
     8521 attgtcttga tgatctgcat ttaaaacaac tgtgatgact ctcatgcctt tttcgacagt
     8581 agtaccaaca aaagactctc cagccttatc tgttgttcct gtttttagcc catcaaaacc
     8641 accacggtaa gcaggcatac cttctaacat gtagttggtt gaagtgattg tcatcccagc
     8701 aaaagtagaa gaaggttttt tggtgatttc taagacttgt gggtattttt tgatgaggtt
     8761 gcgagcaacg atagcgacat cataagcact aagcttattt tcctcatctt ttttagaacc
     8821 tgggtaaatg ttatccccta gagtttcatt gttaagacct gtcgtattga caacagtggc
     8881 atcctgaatt ccccattcca agagttttgc ccgcatcata tcgacgaaat ctttttctga
     8941 gccagcaatt ttctcagcta gggcaatagc ggcgctgttg gcactagata ccagagttgc
     9001 ttcaagcaac tcttcgacag tataattacg ggcctccata ggaatattac tggcttcaga
     9061 atttgtcgtc aattgataag gataatcaga aatatctaca ggagtggaga gggtaatact
     9121 tccgttttcc aaagcttcat agaccagata aacagtaatc aattttgtta tggaagcaat
     9181 ttcgacaggt tgcgttgcat ccttctcata gagaatttta ccagtatttg cctcaacagc
     9241 aatcgcatgt ttagcggcaa tggtaaaatc ttgagcaaca gcagtagaag caccccctaa
     9301 aagagagaca gttaacaaag ttaaaaatat ttttttcata gtagtcttat tctatcataa
     9361 agaaaaaaaa tattcttgct ttaataattc atctgttaag ctttttgaaa atatggtaaa
     9421 ataaagtgag ggaggtaact catgtttcgt agaaataaat tatttttttg gaccacagaa
     9481 attttactct taaccatcat cttttaccta tggagacaga tgggatcttt gattaaccct
     9541 tttgttagcg tgcttaatac aattatgatt ccatttttat tagggggctt tctttattat
     9601 ttgacaaacc ctattgttac tttcttaaat aaagtctgta aactcaatcg tttgcttggt
     9661 attttaatta ccttgtgtac tttggtctgg ggaatggtca taggtgttgt ctatctctta
     9721 cctattttga ttaatcagtt atctagtttg attatatcta gtcaaactat ttatagtcga
     9781 gtacaagact taatcataga cttatctaat tatcctgcgc tccagaattt ggatgtagaa
     9841 gctacaattc agcagttaaa cttatcctat gttgatattc ttcaaaatat cctaaatagc
     9901 gtatcaaata gtgtggggag cgtcttgtca gctcttatca gtactgtttt gattttgatt
     9961 atgactccag tttttttggt ttatttctta ttagatggac ataaattctt gcccatgctt
    10021 gaaagaacga ttctaaagag ggatcgcttg catattgcag gcttattaaa gaatttaaat
    10081 gcgacgattg ctcgctatat tagtggagtt tcgattgacg caatcattat aggttgtttg
    10141 gcttatattg gctatagtat tattggttta aaatatgctt tagtttttgc cattttttct
    10201 ggtgtagcca atttaattcc ttatgtgggg ccaagtattg gtttgattcc tatgatcatc
    10261 gcaaatatat tcactgatcc ccatagactg ctgattgcag tgatttatat gcttgttgtt
    10321 cagcaggtag atggcaatat cttatatcct cgaattgtag gaagtgttat gaaggttcat
    10381 ccaatcacga ttttagtttt acttttgttg tcaagcaata tctatggtgt agttggaatg
    10441 attgtcgcag tgccaaccta ttctatcttg aaagaaattt ctaagttctt atcccgtttg
    10501 tatgaaaatc ataaaataat gaaagaacga gaaagagaat tagctaagta aaagtcagga
    10561 gaaccctgat ttttctttac tggaagtggc ctttagatta gaagactgaa aataagttaa
    10621 agtcttaaac taattttcac agctaagaat agtagaagtt aatctgataa aaatcgaaaa
    10681 aaccagtgga attccgtgtc agggtaagtt ccactggttt tcatagtcta ttaaagttcg
    10741 aatgaaacct at
//
LOCUS       DAVMCN010000056        10721 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVMCN010000056 DAVMCN010000000
VERSION     DAVMCN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.057"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..200
                     /locus_tag="VYP85_001696"
     CDS             <1..200
                     /locus_tag="VYP85_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEV1882176.1"
                     /translation="PDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNN
                     KRIKVKLKGLSPVQYRTKSFG"
     gene            complement(316..1119)
                     /locus_tag="VYP85_001697"
     CDS             complement(316..1119)
                     /locus_tag="VYP85_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1882177.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQARGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNARTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1402..2157)
                     /locus_tag="VYP85_001698"
     CDS             complement(1402..2157)
                     /locus_tag="VYP85_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1882178.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2227..4878)
                     /locus_tag="VYP85_001699"
     CDS             complement(2227..4878)
                     /locus_tag="VYP85_001699"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1882179.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(4871..5449)
                     /locus_tag="VYP85_001700"
     CDS             complement(4871..5449)
                     /locus_tag="VYP85_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1882180.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5449..6009)
                     /locus_tag="VYP85_001701"
     CDS             complement(5449..6009)
                     /locus_tag="VYP85_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882181.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5996..6313)
                     /locus_tag="VYP85_001702"
     CDS             complement(5996..6313)
                     /locus_tag="VYP85_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882182.1"
                     /translation="MERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFA
                     KILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKD
                     GKN"
     gene            complement(6857..7252)
                     /locus_tag="VYP85_001703"
     CDS             complement(6857..7252)
                     /locus_tag="VYP85_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1882183.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7348..7602)
                     /locus_tag="VYP85_001704"
     CDS             complement(7348..7602)
                     /locus_tag="VYP85_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1882184.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(7612..8946)
                     /locus_tag="VYP85_001705"
     CDS             complement(7612..8946)
                     /locus_tag="VYP85_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1882185.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIADESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8946..9179)
                     /locus_tag="VYP85_001706"
     CDS             complement(8946..9179)
                     /locus_tag="VYP85_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1882186.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            9210..9284
                     /locus_tag="VYP85_001707"
                     /pseudo
     CDS             9210..9284
                     /locus_tag="VYP85_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9641..9823)
                     /locus_tag="VYP85_001708"
     CDS             complement(9641..9823)
                     /locus_tag="VYP85_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882187.1"
                     /translation="MNPIKAFAKIYGNYFLTMQGVKVMKTIKKDDNVVVGLGKLFIAD
                     KLMDAARWLIKPEERE"
     gene            complement(9825..10604)
                     /locus_tag="VYP85_001709"
     CDS             complement(9825..10604)
                     /locus_tag="VYP85_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882188.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMVITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT         3120 a         2384 c         1986 g         3231 t
ORIGIN      
        1 gcccagacaa tggtatgatg gagtccttct ttgggattct gaaatcggaa atgttttacg
       61 gttatgagaa gtcgtttcag tcgcttaagc aattggaaca agccattgta gactatattg
      121 attattacaa caataagaga attaaggtaa aactaaaagg acttagccct gtgcaataca
      181 gaactaaatc cttcggataa attaattgtc taacttttgg ggggcagtac attttaacac
      241 ttgatactat gcgttttatt gtgggaatgt ttacttcatt ttttcctaaa attcaatgtt
      301 tactcagtat ttggattatg aaaaatcgag gtctaaatct agatacattt tttctgaaga
      361 caaatcattt tgaccaccga gcaagagatt ttcaaaaaaa gctgttaaaa actcaggacg
      421 tcgctgtaaa atctttgcat tatctaatac caaggcatca cgaaaatact tggaatgttg
      481 ctgaaatggt atattatcaa tatcaaaacc aaactcacga agatactgaa tcaaaaagac
      541 cgttactgtc cgagcgtttc cttcgcgaaa tggatgaatc tgccagattc ctgaaataaa
      601 atgctggatt tttttaacca tatccgcctg ggttagtgtc gcatatgcaa cttgtttttc
      661 ctgattaaaa tcataatcca atgtcatttg aatcatggag taatcagagt acacaacact
      721 ttcaccattc aaaacaggtt cattctttgt gatattagtc tgacgaaatt gacctaccgg
      781 aatcgagggt tcaaatatat cttgaaacaa ctccttatga atagcaagta aggtcgcagg
      841 actgaagcta aagcctcttc gagacaatag ttctacaatg cgtagagaaa ccaagtctgc
      901 ctcctccgta cttgcatcaa tagtatggtg ataagccgtt gcatcctcat aaacctgctc
      961 ataagtcagt tcaccccgag cctgtttctc agccaaagat tccatataag ctgatggcac
     1021 tagattgtca actttctgca gaccaaaacc tatccgccat aaatcacgct tagcttcata
     1081 agacaagttt ggattgtcaa tgttgtaagt tggttgcata gaaatatcct ttcaattgtt
     1141 tttcttcatt accagtaaat cacgaaattg gttggaaact ggcttaaact ataaaaagtc
     1201 ctcacaatag gttctatgat atatatatat atatatactt catgtaaata ataaaagagt
     1261 tataatcagc actactgata aattcaatac cgatttcgcc atcttaaaac ttagtcaaac
     1321 gaataccgtt gatttccagt tcattaagtc gttgacctat caagacttct cgttccttca
     1381 actggaaaag ttaaggggga actaatacaa atcctctacg cttctatatt caatgatttc
     1441 atttttgata atattctttt taaactcaaa atgttttaaa ggattatcga ttaacactaa
     1501 ctttggaata tcatctagat ttgtgaccaa ggataaaata aaatccgatt gaaactcctt
     1561 gactttttca aattcttttg cagttaaacg cacacgcccc ttagattttc ggataccttt
     1621 tacttcggca aggtaagaat actcttggac atctacctga aagtcatatc catcaccata
     1681 aagacgggca tcggttaact gtccaccttg gaatttttct tctttatcaa aatgaaggat
     1741 aaaataattc tcagcctcca ttcccgtttc ctgtagacgt ttgaatttag ttcgaactat
     1801 tggtttttca acgatggtta tgcctgtttt cttcccttca ctggcaagta acattttaac
     1861 tatttcagca taactatgaa catcttcatt tccaaacatc atatcaatta aatctttacg
     1921 aaaacgataa acttcagctt tctgccacca accttttcga ttattgtcaa aataaggatc
     1981 aaataaatcc attctatttt ttacaactcc agttgtttca gcaattccca gagaaaccac
     2041 atagcgataa aactccgact tgctagagca ttgaaattct tttataaaaa gcttgtcaaa
     2101 cttggcaaga ccgtagccaa ttaaatttaa caattcataa tgagggtgtt tggacatcac
     2161 tttctccatc aatagatatt gatttcatta taccaaaaaa cacggctcat caccgtgttt
     2221 ctgtgtttat ttcaccaact tcttcatctc atcaatacgt gctacggtca catcatactt
     2281 ggcttggtag tcggcttgtt tgtctttttc tttttggaca acttctggtt tagcgttggc
     2341 gacgaagcgt tcgttagaga gtttcttacc aaccatgtcc agttcttttt gccatttagc
     2401 gagttctttg tcgagacgag ctagttcttc ttcaacattg aggagatcgg ccagtggcaa
     2461 gaagatttcg gctcctgtaa taacgcttga catagccagt tcaggtgcag ggatggttga
     2521 tgcgatttcc aagtgttctg gatttgtaaa gcgtttgata tagttgacat tgctgttaaa
     2581 gaaggcttcc aagtcgctat cgcttgtctt aacaaggatg gtgataggct tgcttggtgc
     2641 tacatttact tccgcacgcg cattccgaac agcacgaatc aagtctttga gactttccac
     2701 accagtgtga gccgcaaggt cttcaaaggc tagattaaca gttgggtatg cagctgtcac
     2761 gatagaacct tctgagattt gtccaaagat ttcctctgtc acgaatggca tgattgggtg
     2821 aaggagacga aggatcttgt ccaaagtgta tagtagaaca gaacgtgtga tgactttctc
     2881 ttcttcgtta tcgctataaa ggacttcctt ggtcaactca acataccagt tggcaaattc
     2941 ttcccaaatg aagttgtaaa ggatatgacc agccacacca aactcgaact tatcaaagtt
     3001 ttcagtaact tttgcaatgg tttcgttgag attgtggaga atccagcggt ccgtcacatt
     3061 accagcctca cctgttgcaa cttttgtgac attgtcatgc gccacatcca gcgtcaaacc
     3121 tccattgttc atgaggatat agcgagaaat gttccaaatc ttgttaataa agttccatga
     3181 agcatccatt ttctcataag agaaacgcac gtcttgtcct ggcgcagaac cgtttgaaag
     3241 gaaccatcga agggcatcgg caccgtattt ctcgataaca tccattgggt caatcccgtt
     3301 accgagagac ttagacatct tgcgtccttg ctcgtcacga atgagaccgt ggataaggac
     3361 gttttggaat ggttgacggc ctgtgaattc caatgactgg aagatcatac gagacaccca
     3421 gaagaagatg atgtcgtaac ctgttaccaa ggttgaagtt gggaaataac gtttaaagtc
     3481 ttctgagtcg acttcaggcc agcccatggt tgaaaatggc cagagggcag aactgaacca
     3541 agtatccaag acgtcttcgt cctgagtcca tccgtcacct tctggagctt cttcgccgac
     3601 atacatttca ccatcagcat tgtaccaggc agggatttgg tgaccccacc aaagctgacg
     3661 agagataacc cagtcgtgga cattttccat ccattgaagg aaggtatcgt tgaaacgagg
     3721 tgggtagaat tcgaccttgt cctctgtgtc ttggttggca atggcgttct tagccaattg
     3781 gtccatcttg acgaaccatt gagtagacaa gcgtggctca actacgacac ctgtccgttc
     3841 tgagtgaccg actgaatgga cacgtttttc gattttgaca agggcaccga tttcttccaa
     3901 cttagcaacg actgccttac gagcttcaaa acgatccatg cctgaaaatt caaaggcaag
     3961 ctcattcata gttccgtcgt cgttcatgac gttgacttgt ggcaagttat gacgttggcc
     4021 aaccaagaag tcatttggat cgtgggcagg tgtgattttc acgacaccag taccaaactc
     4081 aggatctgcg tgctcatctc caacgattgg gatgagttta ttagcgattg gaaggatgac
     4141 gtttttacca atcaagtcct tgtagcgcgg gtcttctgga ttaatcgcaa ccgcaacgtc
     4201 cccaaacata gtctcaggac gagttgtagc aacttcaagg gcgcgtgaac catcttccag
     4261 catgtaattc atgtggtaga aggcaccttc tacatccttg tgaatcacct caatatcaga
     4321 aagggctgtg cgagctgctg ggtcccagtt gatgataaac tcaccacgat agatccagcc
     4381 tttcttgtaa aggtccacaa agaccttacg aacagctttt gacaaacctt cgtcaagagt
     4441 gaaacgctca cgagaatagt ctacagaaag ccccatcttg ccccattgtt ccttgatggt
     4501 agtggcatat tcgtctttcc attcccagac cttcgtcaag aaagactcac gacctaggtc
     4561 ataacgcgta ataccctcac cacgtaagcg ctcctcaacc ttagcctgag tcgcaatacc
     4621 agcgtggtcc atacctggaa gccaaagggt atcaaagccc tgcatgcgtt tttgacggat
     4681 gatgatatcc tgcaaagtcg tatcccaagc gtgaccaagg tgaagtttcc cagttacgtt
     4741 tggtggtgga atcacgattg aataaggctt agccttttga tcgcctgaag gcttgaaaac
     4801 atccgcatca agccattttt ggtaacgacc agcctcaacc tcggctggat tgtatttaga
     4861 tgaaagttct ttagacatgt gtgtgtcctt tctctatttt gtttatttta ttttgaattt
     4921 gcttagcagc ttcttctgca gacaaattcg tattatttat tttaaagtag tggtgcaact
     4981 cattcggttg atattgggaa tttaattgaa gtgtttcagc ggtctctaaa atttctcttt
     5041 cagatacctc aatatgtcgt tttaagggtt tgtactttaa tcgattctcc gttcgatttc
     5101 gacgtatgca ctcttcaaga cttgtttcca actcaacaaa aagaatctct tgatgataat
     5161 catccaacaa attctgaatt tgctttaaat acatcagctg atactgattt gaaaaatcaa
     5221 ttacatctgt taaaattact gatcgctgat ttcttgcact tgctccaagg aatgaaaaag
     5281 tgattccacg aacaaattcc cacatttcct ctgtatagtc ctgatagatt tctagtgcaa
     5341 aatcaatggc ttgatggtta taaaataggg tagcatccgt cagtcgagat aattcttgac
     5401 caatggtcat ttttcctgat gctggagcac caatgatgaa aagatgcatc aaatcacctc
     5461 ccactcactc ttcagcaagg catatctcaa atcatcacag cagttgcctt gagcatcttt
     5521 acggtctctt atgcgagctt cgagggtaaa gccaagcttt tccgcgactc gttgactttg
     5581 aaggttatat ccaaagcaag ttagttcaat cttgtgaaga cccaaatctt taaaggctaa
     5641 gtcaatcaag gcacgcgcag cttctggcac ataacctcgc ccccaatagt ctgagtgtaa
     5701 ggtatagccg atttccatca catcatcttc atggcgatgg ttgaaataga tagagccaac
     5761 gatcttatcc gttcctttga cgacaatccc gtagcctgct gggagatttt ccttttgatt
     5821 acgctccgga agaatgtgct ccagataata aatctcatct tccaaggtct tgactggagg
     5881 aaaacctgct ggataggcga cctctggcaa actagcatag tcaaagatat cctcagcatc
     5941 cgccacagta cggactcgta aaacgagacg ttctgtttcg attttatctg gcagctcagt
     6001 tcttgccatc cttcttcctc gcttttttga tgaaactgcc cttcatatct acacgcttgt
     6061 ccagatagcg ataaacgcgc tgatatccat ctcccatgaa ataggttggg gcaaacagtt
     6121 gatttttaaa atgtcccttt tcatccagga gttctggggc aacaagtcgc tcaagaatct
     6181 tggcaaagat gtggcaaata ccgtcttcct caacaatcct atctacccga caatctaaaa
     6241 caagtggaca ggcgtctaaa ataggaatct gagttcgttc agaaatttca taatgcactc
     6301 ccaaacgttc caatttctcc tgatgactga taaaaccagc ctactccatc gcaagcatag
     6361 aagtttcatc agaaatattc acagtaaatt tttgatactg tttgatctgc tctgcggcat
     6421 tctctctcgc aacgactcca atcacaaccc aatctcctag actataagag gaactacagg
     6481 tcgtgatgtt atagccaaaa ttctaatctt gatatcctaa aataaaaaca ggaaaaccat
     6541 aatatagttt attagtttta aatgattgtt ttataacaac ctcctttgac taagacacaa
     6601 aagaaaagcc ctgccatcta catgacaggg acgaatgtgt ttatccgcgg taccacccaa
     6661 tttcgggcca agcccgcatc tttagtcttt aaaataaaaa gacagaaata tttcattttt
     6721 tcagtcatta gcaaccagtt ttgacacatt tgtggacttc tcagcgccgc cactttctgt
     6781 aaaatgtggg attcaaaaca cctctaatgg ctctattgta gcaagttttt ctcggaaatg
     6841 caaggctcaa gaaaaattac ttgaacttga tgccattttc tttcaatttc ttgatggtag
     6901 ctgggccgat tcctttcaag gcaaggagtt ctttttcagt ccagtttttg aaatctgaag
     6961 cagacttgat tccttcatca tagaaagttt tggcacgatc aagtggaagt ccacccaagt
     7021 ttgctgcaaa atcttctaca gaattagcta ctttttgagc ttgctctttg gtagcttcta
     7081 ctgcttgttc aactttttta gaaacagcct taccagctgc gcttgctgac tgttctgcac
     7141 gcttcacgac tttttttgtc tcatctacaa ccttagtcac agtacttgaa aaggcacctg
     7201 cgcgacggag gccatttcgt aattgttttt tacgattgag tttctttgac atgataaaat
     7261 cctttcaata aaaaatccct gctctgacaa ggatttaaca taaacattct atcaagattt
     7321 tagtgaaaaa tcaagaatct ttctcgttta ataatttcgc tcaccaaaca agccttctgg
     7381 caaatcatgg aatcccttgc ctgctttgaa gttttcaaac ttaccaagca agaactgata
     7441 agcatccaag cgactctcgt agcgaatcat ggcatctttg gcacgctcgt cctggtcttc
     7501 ttcgtaaact ttttgacttt ccttgtgcgc catgtcgtta atcatgattt gggtattgac
     7561 ccaagcttca aattccttca taaattcttg ttcgtaactc attttttctc cttattctaa
     7621 tccacgaaaa tagtccgtat caatctcacg gtagggctgg atatcctgaa catactccaa
     7681 cactccttgg aattctccgt cttcatcgtg tactgcagca taggtgatgt ggacaaactt
     7741 acctcgcgac tcagacttga accacatttc atacttgtcc ttggtcccct cacgaagccc
     7801 cttcatgata gttttgacct tgtccaaata cttaggcgga tgacagagtt cgacattgcg
     7861 cccgacttgg gacggcgtcc gtttgaaaat catctcatca gctggcgtat tgtcattgta
     7921 atactggaaa atatcttctt tattgacaaa ggtaatctcc atagggagat gattgaggat
     7981 gagattggcc tgctcgactg aaagatagcc attaccaaaa gcctgttgac tatggcggtc
     8041 cagcacagct tccttttcct taggggtaaa ggtaatggta aaatggcctt ctggcgtatc
     8101 tatgacttgt tgaacttgac cttctgccgt atctagctgt acaggctcct ctgcaatctt
     8161 ttcctcaata aagctctgtc gttctggcac ccatttctct gacggacgga tgatggcata
     8221 gccataggca tcgctctcat ccgcaatctg aagccagtca tcctgagtaa aagactcaag
     8281 gagaatcatg aggaggatgg actcttcctt gaaaatcata ctttcaaact ctgtcgcaaa
     8341 agcttcaaaa gcttccttta cactgctaat tgacacttct ggtagtgact tggctgtcgt
     8401 tagagctgtt tgaaagagtt ccctaatctg atcatccact ccccacataa ctttgggagg
     8461 tgaatcgtgt ccatagcgct ccatgatagg aaagaagagt tcttccttac gttggtaatg
     8521 gatgtcaaat tgccccacaa gtcccatctg acgcaccaag cccttgcgca tctccgcaag
     8581 catttcctcg tcttccatag actcataggt atctaacaat ctacgaatgc gaatcaaagc
     8641 tgcacggagg gccaaatttt cttccttaaa gacacgaact gggtgcccag ggtgttcggt
     8701 atctaaaact tcgacacctt tgatagcatt tttaaaaaga ttggcatgga catcacagag
     8761 ttccataaca tcttcaaaag tgacgcccga atccgagttc atcagctcgt gctccataag
     8821 ggaaatctca atggctgaga cacccgcaaa ggtcgcatca aaacgctcct gaaccgactc
     8881 aggagaggcg ccattatgca attctaataa aatatcccgt aggacatgaa tccgttcatc
     8941 tgccattagt ctaatccaat cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg
     9001 tccataggag ttcctgctag cttagaacct tgtttaagtg atactttacg accaactgta
     9061 ttgcgcatca agggattggc aaggggttta aaacccagct ccactagaat ttccaagact
     9121 tctggatgct tgtccaccac ttctgcaaca ggaattgaca catcgatgat attgtccatg
     9181 acgacctcca ttatatgttc taatactcaa tgaaaatcaa agagcaaact agaaagctag
     9241 ccgcaggttg ctcaaaacag tgttttgagg ttgtagatag aactgacgaa gtcagctcaa
     9301 aacaccgttt tgaggttgtg gatagaactg acgaagtcag taacatatat actgcaaggt
     9361 gaagctgacg tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt
     9421 ataccatatg gaaagagatt aaaaaactag cagtagagtt cctgctagtt ctctgcgatt
     9481 ttgattacca tctaaataag tttaaagagc caatccaata ttttaaataa tagcttgtaa
     9541 aacagcaatt gaactgcaaa agagataatc atccaaaaga atttcacaat cccaataatc
     9601 ggtttaataa aaagaatggc aagaattgcc aaaaaaaatt tcattctctc tcctctggct
     9661 tgatgagcca tcgagccgca tccattaact tgtctgcaat aaaaagtttc cctagaccga
     9721 caacgacatt gtcatctttc tttatcgttt tcattacttt tacaccttgc atggtcaaaa
     9781 agtaattacc ataaatttta gcaaaagctt tgataggatt catctcactc accctcgatt
     9841 atttcagcct cttttcggat tgtttcaaca tcttcttgat attgaacttc actatagttg
     9901 actagtttag acaattcttt ctgcaagctt tcacccatcg gtttcatagt tgcaaaggtt
     9961 aaaccacctg aaatgatacc acccaagata ggaatgaatt tccccattcc tttggccagc
    10021 cctcccttgg taagattcac accaaatatt tttaagactt ttttcaaaat aggataccaa
    10081 agcgtctttg ttaaagcttt attaggcact gttttcatta cctgtttggc aattgttata
    10141 ccaccagcac gtagcaaggc agcggttcca ttcaccccca acattacgcc tagataaagc
    10201 aagagggtat tttgagcatc ttcactcaac tcctcgcgtg aagcccaaag atcctcataa
    10261 ccataaatat aacctaattc ttgagccaat ttcagagaga aaccataaaa ttgagccaca
    10321 tcagctggaa tggtaattac catagcaagc cctccaggta atcctgccaa aacagaagtc
    10381 ccactcgcta ataaaacatt atccctaata caggcattag ccactcgatc taagatttct
    10441 tgagataaga gagacgttgg accttgttcc aataaggtag gaatgtcctg tggacccaat
    10501 tctttggaaa acttatccac taaaaatttc gaacgatcaa ccttaacaac tggtagtttt
    10561 accacttgtt gtaatacttg catagctaag tcttgttcag ccatatacaa actccttatt
    10621 tcttttttac accttatcat attatatttc ctacaaaaaa agcattttct aattagataa
    10681 cattaaaaaa tacagaaccc cttttttata ttaaaatgaa a
//
LOCUS       DAVMCN010000057        10704 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVMCN010000057 DAVMCN010000000
VERSION     DAVMCN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.058"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(66..1490)
                     /locus_tag="VYP85_001710"
     CDS             complement(66..1490)
                     /locus_tag="VYP85_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1882189.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2035..4314)
                     /gene="pulA"
                     /locus_tag="VYP85_001711"
     CDS             complement(2035..4314)
                     /gene="pulA"
                     /locus_tag="VYP85_001711"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1882190.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4426..6384)
                     /gene="ligA"
                     /locus_tag="VYP85_001712"
     CDS             complement(4426..6384)
                     /gene="ligA"
                     /locus_tag="VYP85_001712"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1882191.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6477..7655)
                     /locus_tag="VYP85_001713"
     CDS             complement(6477..7655)
                     /locus_tag="VYP85_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1882192.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7735..8598)
                     /locus_tag="VYP85_001714"
     CDS             complement(7735..8598)
                     /locus_tag="VYP85_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1882193.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8601..10502)
                     /locus_tag="VYP85_001715"
     CDS             complement(8601..10502)
                     /locus_tag="VYP85_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1882194.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSHRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3212 a         2355 c         1915 g         3222 t
ORIGIN      
        1 ctataattat tattatttta tagcaaaaaa ataaaaccag gaaaacaatt tcctgatttt
       61 acacgttatt tcacatcaaa aacaatggat ttgacatttg tcatcgcttc aatgctatat
      121 ttaattcctt gcactccagc tccagaacct ttgacaccaa ggaatgggaa attatctgga
      181 ccacgctggg ttttattatt aatgtggact gtacctactt caagtttttc agcaatttca
      241 aaggcttttt tgaaatcatt tgtaaagact gatgattgaa ggccgaattc agattcgttg
      301 gcaaaggcaa tagcttcctc tacactagcc acacgaatga ttggtaaaac aggaccaaat
      361 ggctcttccc atgccacttt catatctttt gtaacttggt caaaaagcac tggccagagg
      421 agattgccct cacgtttgat tggtgtaaga gcctgagcct ctttttcttg tgcatcctca
      481 atcaagcccc aaatgaagtc ggctgaagca ttgtcaataa caggtgtaat atcagcattg
      541 tcaaatggat caccaactgt taatttagaa acttcttcct gaagcaaagt agctaattta
      601 tctgctacac tttcgagaac aatgacacgt ttaatggccg tgcaacgttg tcctgagtag
      661 ctaaaggctc ccgcaacaat ttgcttggca gcatgttcca aatctgcatc ttctagtaca
      721 agagctgcat ctttcccacc aagttccaac atgataggac gcataccagc taaacgacca
      781 atacgttctc caataggggt tgaacctgta aagttgatga agttgacttc tttgtgctca
      841 atgatataat ccccaatttc tgaaccacga cctgtaatgg tgttgaaaac acctgccgga
      901 atccctgctt cttcaaatgc tttagccaac aagagtccag aaatggaacc ttgtgttggt
      961 ggcttaaaca tgaccacatt ccctgcaatc aaggcaggtg caattttaga agcagataaa
     1021 ttaactggat aattaaaggg agcaatcgct agcacgatac caactggttc acgacggaca
     1081 acagccagtt tgtttttact tgctgcctca aaaccaccac cttccattgc ttgtccagtg
     1141 atacggagac cttcctcagc agcataacga atcaagtctg ctgtacgcac tacttctcca
     1201 attgctgctt taatcccttt tgctacttct ttggcaagga tagtaccaat tttttcctta
     1261 tcgcgttcta aaatagctgc tgttttatgc aaataagccg cacgttcaat tgctgataaa
     1321 gctcgccatg ctggcagggc tgcacgcgca gcttgcatag cctcatcagc ttcagtctga
     1381 gtcatggctg gaactgtacc caattcttct tgattgattg gtgaataaat cgtaatttct
     1441 tgttcagatg atttccattt tccatttact aaattctgat atcttgtcaa attcttgtcc
     1501 tcctgaaaat gattaagata tattttacca aattttcaga aaatcacaac cctttttgca
     1561 aaatttttga gattattttc acaagcttga tttttcaaag tatactcaat aaaaataaaa
     1621 aaaatccact acatcaaggc gagactaatg tggtttgaag aaattttcga agagcgtgaa
     1681 tgagtatcat ctatagtaaa ataaaaaaac tgaacaattt ggttggggac agtcaaacca
     1741 atttctcaca atgttttaga aacaagggtg tgctattcca atttcaggct actataactg
     1801 tcatagattg ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga ccccctatca
     1861 agtgttcaaa aactttgata ggaggtcttg ttttgtgaaa atatttatca aattttctat
     1921 acaagtgagc tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta
     1981 ccaatactca taactgggaa tttgtctgtg taaaaatagc gagatagatg gtatttataa
     2041 aacactcaag acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt
     2101 ggttaccaac atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt
     2161 cacaactacc aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc
     2221 aatcgcagaa tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc
     2281 accagttttt gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc
     2341 attaatcaag ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc
     2401 acgctctcta tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg
     2461 accaaattct tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt
     2521 ggcagtttcg accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa
     2581 taaatcgtga agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg
     2641 tgtataggtt cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc
     2701 agcaccactg acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc
     2761 gcgctgattg tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc
     2821 cttatcataa ggggtaagac ctgttcccat atcccatcct tctccataga ggataatgtt
     2881 ggagtcgatt tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc
     2941 catcaagtca aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc
     3001 aatcatatac ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc
     3061 attctggaag gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa
     3121 tggtgcatca acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc
     3181 cgcatcgtga taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc
     3241 tggattagtt gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt
     3301 gtaggttaca tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg
     3361 aacataattg tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt
     3421 aactgttcca gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga
     3481 tgtaggtgat ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt
     3541 ttccaagcgc caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc
     3601 tacatggctc agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc
     3661 acgtgtcagt gtttggtgat gagggaattg gacttgatac tgataagtct tacctaccaa
     3721 atcttcttca acatccaaac tccagacacc gattgtattg tccttatgat tataagagta
     3781 gctattgcct cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc
     3841 ataaacgaca acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt
     3901 gtcctctaca cggcaaccca attctccttg gtaaccccaa tgatgatcaa aactagcact
     3961 gttaatggcc ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc
     4021 aggattttca gagtaataaa tcctatcatc gccttccaaa atccagacct ctgtcaatag
     4081 gggatagtga ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa
     4141 attcaagctt tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata
     4201 atcttctttg taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt
     4261 gtcatattct ccattcttac gatggtaatg aatgcgcata gggtagttat acatttttta
     4321 tttttccttt ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt
     4381 aacagacata gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag
     4441 ccatgcctca tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc
     4501 gtctgcacct accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc
     4561 cagactttcg agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa
     4621 taccacggtc aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag
     4681 attgacccca gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata
     4741 agtctgaaga cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga
     4801 atctgcctga tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt
     4861 gcttccgaca tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga
     4921 tgcttggata gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag
     4981 gaaatcctct tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa
     5041 aagcttctca acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa
     5101 gtgaatcaag ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac
     5161 ttcatcttca aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag
     5221 tttttcttca gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc
     5281 agccttatat acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac
     5341 attgtgcagg gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc
     5401 agttggagtt acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc
     5461 tttttcttca gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc
     5521 aagttcttct tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg
     5581 cagattttcc cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc
     5641 agccaagatt cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt
     5701 ttcttggcta tcacgagttg aagggctggc ttcttgatag agaaacgttg caagattacg
     5761 cttggcaact actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt
     5821 agcaaattca ggctctccat tttcttggcg cacttggtta acttggtcaa aggaagcgcg
     5881 tggcatgtaa cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat
     5941 gtccttaaca cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt
     6001 taccccagca accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt
     6061 cagctcacaa atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc
     6121 tagctcctca cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt
     6181 ttcaaaacca tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg
     6241 ctctggataa gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc
     6301 tgaaaccgag ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac
     6361 taactcattc attcttttat tcataagacc attttaccat aaaacaaacc ctcctcacaa
     6421 acgagaagga cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat
     6481 atcaattttt caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca
     6541 ccacttccaa ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct
     6601 tttgcaatag gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga
     6661 aattcgctct caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata
     6721 aacaattcac aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc
     6781 ataaaaactc cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta
     6841 attttactag ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt
     6901 gcataggctc cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct
     6961 gcaaaaaaga aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc
     7021 cagatatagt gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt
     7081 ttctcttgaa cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa
     7141 aaagtcagcg agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag
     7201 gaaagaacag gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag
     7261 atcacaatct catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa
     7321 aaggcaaaag caatagcctg cacaatgtta gcaacaatca aagcgccaat catccagcta
     7381 tcattcctta tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt
     7441 aaaatcttac gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata
     7501 gatgtgacga gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata
     7561 gaagccaacc agacactatt tccataatca tagagcatat ttcccatttt attgatagcc
     7621 ccacggctaa tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa
     7681 actattgtat caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact
     7741 tttgacaaat ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac
     7801 atcaaaaata tgtatggcct cttgcatctg cttacagcct tctttacact gtcctttttg
     7861 atataaggca aaacctttta aataatggaa aacattacgc tcataaagct taataccttt
     7921 gtcaataatc ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc
     7981 taaacaatgc tggtaacaat tgagggccaa aatcaaaact aatctcttat ggcgactaat
     8041 ctcttggtaa aattcctccc tctccataac ttctctacca atccgagtga catagtctac
     8101 atcgtagaaa ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt
     8161 tttgaagaga taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc
     8221 tctttgacaa atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt
     8281 cgaactctta gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt
     8341 tgaatagtaa agtgggataa tctgtgccat catagacaca tgttcatgat tgtgaaaatt
     8401 ccttgcctta tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa
     8461 acgggagact gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca
     8521 ggattcgcct gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac
     8581 ttttccaaga tgttccatct ttacacctga tctgataatt cttcccactc aagcatagct
     8641 tcttcctgac gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca
     8701 tcgtttgttt ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt
     8761 tcagcttcta gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc
     8821 tgggcctgat agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc
     8881 tcagtctgac tcatttctgc tgttgctttc ttctcaacat agtagtcgta atctccaagg
     8941 tagagagttg aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag
     9001 taacgatcat gactgacaaa aagcaaggta ccatcaaagt caatcaaagc attttccaac
     9061 acttccttgc tatcaatatc caagtggttg gtcggctcgt caaggatcag gaagttgttg
     9121 ttttccatag acaatttagc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg
     9181 actgattttt taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca
     9241 acttctggtg tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc
     9301 agcttgcttt gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttca
     9361 cctttgataa aaggaatctg gtccacaata gacttgataa aggttgactt gccgatacca
     9421 tttggaccaa cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac
     9481 aagacttccc cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac
     9541 gttttttcag actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa
     9601 cgctccattt tttctagttg tttacggtga gattgagcac gtttagtcgt tgaagcacga
     9661 actagattgc gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag
     9721 ttttttgcct cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc
     9781 acatagcgat ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag
     9841 aaataacggt cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct
     9901 agccaggcga tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg
     9961 ggcttttcaa ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca
    10021 gcaattttca tctgccacat agactcgtca aacttgaatc cattcaaaat cgctcgaata
    10081 tcagcttcat aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct
    10141 gacatcagtt tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc
    10201 agttgtctct ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta
    10261 ttttcagact caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta
    10321 ttgatttctc cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta
    10381 cctgcaccat ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata
    10441 ttatcgaaaa gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc
    10501 ataagagtag tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac
    10561 aacttttata acataaaata aactaaatta tgtatatttt atattagatt cttcactatc
    10621 ttgttggatt ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt
    10681 taattctttt cattatttac gtac
//
LOCUS       DAVMCN010000058        10701 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVMCN010000058 DAVMCN010000000
VERSION     DAVMCN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10701
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.059"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            233..1111
                     /gene="truB"
                     /locus_tag="VYP85_001716"
     CDS             233..1111
                     /gene="truB"
                     /locus_tag="VYP85_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1882195.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            1352..1654
                     /locus_tag="VYP85_001717"
     CDS             1352..1654
                     /locus_tag="VYP85_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1882196.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            1762..2400
                     /gene="udk"
                     /locus_tag="VYP85_001718"
     CDS             1762..2400
                     /gene="udk"
                     /locus_tag="VYP85_001718"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1882197.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            2528..3868
                     /locus_tag="VYP85_001719"
     CDS             2528..3868
                     /locus_tag="VYP85_001719"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1882198.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEDLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVENLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            3846..4058
                     /locus_tag="VYP85_001720"
     CDS             3846..4058
                     /locus_tag="VYP85_001720"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1882199.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            4055..4930
                     /locus_tag="VYP85_001721"
     CDS             4055..4930
                     /locus_tag="VYP85_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1882200.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLQSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            4923..5738
                     /locus_tag="VYP85_001722"
     CDS             4923..5738
                     /locus_tag="VYP85_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1882201.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            5731..6162
                     /locus_tag="VYP85_001723"
     CDS             5731..6162
                     /locus_tag="VYP85_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1882202.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            6169..7836
                     /gene="recN"
                     /locus_tag="VYP85_001724"
     CDS             6169..7836
                     /gene="recN"
                     /locus_tag="VYP85_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1882203.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLESIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            7838..8566
                     /locus_tag="VYP85_001725"
     CDS             7838..8566
                     /locus_tag="VYP85_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1882204.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            8645..10468
                     /gene="lepA"
                     /locus_tag="VYP85_001726"
     CDS             8645..10468
                     /gene="lepA"
                     /locus_tag="VYP85_001726"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1882205.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(10549..>10701)
                     /locus_tag="VYP85_001727"
     CDS             complement(10549..>10701)
                     /locus_tag="VYP85_001727"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882206.1"
                     /translation="KHGFEVVDETDEVSSKHGFEVVDETDEVSNHTYGKATLTWFEEI
                     FEEYKN"
BASE COUNT         3162 a         1942 c         2601 g         2996 t
ORIGIN      
        1 ttagatggca tcaaaagtat actcccatta ttatctttag atgacagacg aaatgtatta
       61 caacatattc aaaaacagaa caattgtcct cctccagaga ttgaggaatt acaaagaatt
      121 atagttaatt aaattttgta aaaaagagaa taaaaggtag acgacgcctc agtaaaaatt
      181 ggcccggaaa aaagcgaagt tcgaagcact gaagggggag tagaaagcaa aaatgaacgg
      241 tattatcaac ttaaaaaaag aagcaggaat gacctcgcat gatgcggttt ttaaactgcg
      301 taagattttg ggaaccaaga aaattggtca tggtggaacc ttggatccgg atgtggtggg
      361 tgttttgccg attgcggttg gcaaggcgac acgcatggtc gagtttatgc aggacgaggg
      421 taagatctat gagggggaaa ttactctggg ttattccacg acgactgagg atgctagtgg
      481 ggaagtgatc gcagaaaccc ctgttttgtc tcccttggat gaaaagcttg ttgatgaagc
      541 gattgctagc ttgactgggc ctattaccca gattccccct atgtattcgg cagttaaggt
      601 taatggtcgc aagctctatg agtatgcgcg tgctggtcag gaagtggagc gtccagaacg
      661 tcaggtgacc atttatcaat ttgagcgaac aagtccgatt tcttatgatg gccaacttgc
      721 tcgattcact tttcgtgtaa aatgcagtaa agggacttac atccgtactt tgtcagttga
      781 tttgggtgaa aagcttggtt atgcggctca tatgtcccat ttgactcgta ctagtgctgc
      841 tggcttacaa ttagaagacg ctcttgcctt ggaggaaatt gctgaaaaag tagaggctgg
      901 gcaattagat tttctccatc ctttagagat tgggacaggt gaccttgtca aagttttcct
      961 aactccagaa gaggctacag aagttcgctt tggtcgtttt attgagctag accaaacgga
     1021 caaagaactg gctgcctttg aagatgataa attgttagcc attctagaaa aacggggcaa
     1081 tctctataag ccaaggaagg tttttagcta gatcgtttag gaataaaaat cgggtgatag
     1141 ataacaattg cttgataaaa ccccatacta atagtagaat ggttttggga attataatat
     1201 tccaattgtt gcgagttgta ggtactcaaa taatctatat agaaatttag aggtgtgaaa
     1261 tgaagcaatt taaaattctt tcagataaat atttagagtc cattacaggt tctggtggga
     1321 acttaggccc aggatttggt gtgataattc catgatgcga aatgagtttc gagaaagggt
     1381 ggagcaactt cttcaacaaa aagaaataaa tgaaaatagt gagttgagtc acctgtttcg
     1441 tcttgctata caaaatttag acagaaatga aaaataccaa tcggtcatgg ccaatttgag
     1501 tcaagggttg tcactttacc tcatgacgca tcattaccag gcacctaagt ctgtcattga
     1561 ttttggttta tggattgcca aagctcctag ccaggaaaga gggagactgg ctttcttgca
     1621 gatgcttgct caaaccctac agggctttcg ttaaaactgt cgaacatcag agggaagact
     1681 ctggtgtttt ttgctgatga gactataaat tttgtaaaaa atgtgataga atagacgacg
     1741 gataaaataa cggaggatag catgcaaaat agaccaatca ttattggagt gacaggtggt
     1801 tctggtggtg gtaaaaccag tgtttcaaga gccattttat cgcattttcc tgatgaaaag
     1861 atttccatga ttgagcatga ttcatactac aaggatcagt ctcatttgac ctttgaagag
     1921 cgtgtcaaaa ccaactatga ccatcctttt gcctttgata cagacttgat gatcgagcag
     1981 attaaggaat tgttggcagg gcgtccggtg gacatcccga cctacgacta tacagagcat
     2041 acacggagta gcaagaccta tcgtcaggag cctcaagatg tctttatcgt tgagggcatt
     2101 ttggtcttgg aggacaagcg tctgcgcgat ttgatggata tcaagatttt tgtggatacg
     2161 gatgacgatg tgcgcattat tcgtcgtatc aagcgtgata tggaggaacg tggccgtagc
     2221 cttgatagcg ttatcaacca gtacttaggt gtggtcaaac caatgtacca ccagtttatc
     2281 gagtcaacta agcgttatgc tgatatcgtc attcctgaag gggttagcaa taccgtggct
     2341 atcgacctgt tgacgaccaa gattgcaaag attttggaag aagctcgaaa cagcaaataa
     2401 tcacatgtgg aggccttgcc tcctttttct atttttccct cataatggta cataaatgga
     2461 gatttttagg catatttttg gtataataat acccatgaaa gagcaagtaa atgaatagta
     2521 ggtggagatg gaaaagtatt tatcggtaac aactttgacc aagtatctga aaatgaaatt
     2581 cgataaagac ccatacttgg aacgggtcta tttaactggt caagtttcca actttcgtaa
     2641 acgacctact caccaatatt tctccctaaa ggatgaccat gcagttattc aagcgaccat
     2701 ctggtctggg atttatcaga aattagggtt tgacctggaa gaaggaatga agatcaatgt
     2761 gattgggcgt gtacaggtct atgaaccaag tggtagctac tccatcatca ttgaaaaagc
     2821 tgagcctgat ggggttgggg cgcttgcgat tcagtttgaa caacttaaga aaaaattgac
     2881 agaagaagac ctgtttcaag aacgcttcaa gcaagctctg ccccaatttt ctaagagaat
     2941 tggtgtagta accagccgta gtggagccgt tattcgagat attatcacga ccgtcagcag
     3001 gcgattccca ggtgttgaca tccttcttta tccgaccaag gttcaaggtg aaggggctgc
     3061 ggaggaaatt gctagaaata ttgcgcgtgc taatcaacgg gacgatttgg atttgctcat
     3121 tattggtcgt ggaggtggtt ctattgagga tctctgggcc tttaacgaag aaattgtggt
     3181 acgagctatt tttgaatctc gtttaccagt tatctctagt gtggggcatg agacggatgt
     3241 gaccttggca gattttgtgg cagatcgacg cgctgcaacg ccaacagcgg cggctgaact
     3301 ggcaacacct gtgaccaagt tggatgtatt agctcatttg caaaatcagg aaaaacggat
     3361 ggcaacggca gtccgaaatg ttctatctaa gaaacaagag gctttgaaaa aatgcagtca
     3421 gtctgttatc tttagacaac ctgagcgctt gtatgacggt tatttgcaac gcttggacca
     3481 actgcaactg cgtttgaaac aaagtttgcg aactcggatt tctgataaca aacaattagt
     3541 tcaagcaaga actcatcaat tagtacaatt atcacctgtt accaaaatcc aacgctatca
     3601 agaccgttta ggacagttgg acaagctctt aggtagccaa atggcgttag tttatgacgc
     3661 caaggttgct gaggccaagc gactttcgga agctttgctc atgttggata ctagccgaat
     3721 cgtggcgcgt ggttatgcta ttgtcaaaaa agaagagtcc gttgtagatt cggttgagaa
     3781 tttgaagaaa aaagaccaag taacgctttt gatgcgagat ggtcaagtag aattagaggt
     3841 taaagatgtc aaaacaaaag aaatttgagg aaaatctagc agaactggaa accattgtcc
     3901 aaagtttgga aaatggtgaa attgctctgg aagatgcgat tactgccttt caaaagggca
     3961 tggtcttgtc aaaagagctc caagctacgc tggataaggc tgaaaagacc ttggtaaagg
     4021 tcatgcaaga agacggaaca gaaagtgatt ttgaatgaaa aagcaagaaa aattagctct
     4081 tgtcgagtcg gctttggaag atttttatgg agaccagcag tttgcctcta gtttacggga
     4141 gtctgttctc tattctattc atgctggtgg caagcgtatt cggccttttc tcttgttaga
     4201 agttctggaa gccttgcagg ttaccatcaa acctgctcac gcgcaggtag ctactgcctt
     4261 ggagatgatt catacaggga gcttgattca cgatgacctt cctgctatgg atgatgacga
     4321 ttatcgaaga gggcggttaa ccaatcacaa gaaattcggt gaagctatgg ccattttggc
     4381 tggagatgcc ttattcttag actcatatgc cttgattgcg caggcagatt tgcaaagtca
     4441 gatcaaggtg gacttgattg ccaacttatc ccttgcttca ggtagtctgg gtatggtggc
     4501 agggcaagtt ttggatatgg agggcgaaca ccagcacttg tctctggaag aacttcagac
     4561 tattcatgcc aataagactg ggaagttact agcctatccc ttccaagcgg cagctattat
     4621 agctgaattg tcacctgaaa tgcaggtgaa gctgaaaact gtgggtgaat tgattggact
     4681 tgcttttcaa gtcagagatg atgtactgga tgtgacagct agttttgagg aaatcggcaa
     4741 gacacctcaa aaggatctgc aggcagaaaa atcaacctat cctgccttgt tgggcttgga
     4801 agagtccatt gccttttgta accaaaccct ggatcaagct aatgaaaaat tggaagaaat
     4861 tgcccagcag cttccctttg aaacagaatc gattgtaagt gtagtagaaa gtttgagaat
     4921 caatggctaa ggaaagagtg gatgtactag cttataaaca ggggttgttt gaaacgagag
     4981 agcaggccaa gcgaggtgtg atggctggcc tagtcgtagc agtccttaat ggagaacggt
     5041 ttgacaagcc aggagagaaa attccagatg ataccgaatt aaaactcaag ggggagaaac
     5101 tcaagtatgt cagccgtggt ggtttgaaac tggaaaaggc cttgcaggtc tttgatttgt
     5161 cggtggatgg cgcgactacg attgatatcg gggcctctac tggaggtttt accgatgtca
     5221 tgctacagaa tagtgccaag ttggtctttg cagtcgatgt tggtaccaat cagttggctt
     5281 ggaaattacg ccaagaccca cgagttgtca gcatggagca gttcaatttt cgctatgctg
     5341 aaaagactga tttcgagcag gagccgagct ttgccagtat tgatgtgagt ttcatttccc
     5401 ttagtctgat tttgccagcc ttgcaccgtg tcttggctga tcaaggtcag gtggtagcac
     5461 ttgtcaaacc tcagtttgag gcaggacgtg agcagattgg gaaaaatgga attattcgag
     5521 atgctaagat tcatcagaat gtccttgaat ctgtaacagc tatggcagta gaggcaggtt
     5581 tttcagtcct tggcttggac ttttctccca tccaaggtgg acatggaaat attgaatttt
     5641 tagcgtattt gaaaaaagaa aagtcagcaa gcaatcagat tcttgctgag attaaagaag
     5701 cagtagagag ggcgcatagt caatttaaaa atgaataaaa aagaaagact tgaaaaaatt
     5761 agaagattgg tgacagatta tcaaatcggc acgcaagaag aaattgtaga acatttgaaa
     5821 gaagcaggta tcactgccac tcaggcgacg gtatcccgag atatcaaaga gttaggtatt
     5881 gtcaaaattc ctttgagaga caacacctat gtctacgaat tgccaaaatc aatcgtaaaa
     5941 agtctgcaac tggctgaaga caatatcgaa tcggctgaat tgatggataa gatgatcaat
     6001 ctccaagtta ttccaggaaa tacggctttt gtaaaagctc agttaatcga gacttttgca
     6061 gacaagattt ttagctgttt gactgatgat agctcgattt tagtcattgc cagaagtgga
     6121 agtctagcag aggaaatctt tgaacaagta aaaaattggt aggtctatat gttacttgaa
     6181 atttcgataa aaaactttgc cattattgag gctatttccc tcaattttga aaaggggatg
     6241 actgtcctga ctggtgaaac gggtgcaggg aagtcgatta tcattgatgc catgaatatg
     6301 atgttgggag ctcgtgcgac gacagatgtt attcgtcatg gtgcaccaaa ggcagagatt
     6361 gaggggcttt tctcagttga gaatagtcgt cttttacagg aaatttttga tgagcaaggt
     6421 ttagaattag gtgatgaaat tatcatccgt cgggaaatct tgcaaaatgg tcgtagtatc
     6481 agccgtgtaa atggtcagat ggttaatctg tctgttttgc gagctattgg gcaacatctt
     6541 gtagatattc atggtcagca tgaccatgag gagttaatgc gtccccaact gcatatccag
     6601 atgttggatg aatttggtga tgccgctttt tgggacttga aagaaaccta tcaaacgagt
     6661 tttgatgcct atcggaaaat gcgcaagcag gttctggaag tcaagaaaaa ccaacaggaa
     6721 cacaaggcac gtatcgaaat gttggaattt caaatggcag agattgaggc agcaaacttg
     6781 caggctggag aagacttggc tctcaatcaa gagcgagata aactcctcaa ccacaaaaat
     6841 attgcggata cactgaccaa tgcctacagt atgttggaca atgaagattt ttcaagtctg
     6901 gccaatgttc gttcagctat gaatgacatg gaaagtgtcg aagagtatga tcctgaatac
     6961 cgtgaaattt caagctctct gtctgagacc tactatgttt tagaagacat tagcaaacgt
     7021 ttggaatcta tcattgagga ccttgatttt gatggcaatc gcctcatgca ggttgagaat
     7081 cgtttggacc tccttcatac tattactcgt aagtatggtg ggactgttga tgatgttttg
     7141 ctttattttg ccaagattac ggaagaatac aatctcttga caggcaataa tctttcgtct
     7201 gaggacatgg aagcagagct taagaagttg gaagtcaatc ttgtcaattt ggcaggtcaa
     7261 cttgcttctg ctcgtcataa tttggctcag caactcgaag ctgagattaa acaagaactg
     7321 caagatcttt atatggaaaa agcccagttt caggttcgtt ttagtaaggg aaaattcagt
     7381 cgtgagggaa atgaaatggt tgagttttat atttcaacca accctggaga agactttaaa
     7441 cccttggtta aggttgcttc tggaggggaa ttatctcgtc tcatgttagc cattaagtct
     7501 gccttttcac gtaaagaagg caagactagc attgtctttg atgaagtgga tacgggagtt
     7561 tcaggtcgtg ttgctcaagc tattgctcag aaaattcata aaattggtca gcatggtcag
     7621 gttttggcta tctcccattt gccacaagta attgcgattg cagattatca attctttatt
     7681 gagaagatta gtaatgacca ttcaacggtt tcgactgttc gtctcttgac ggtcgaagag
     7741 cgagtggagg aagttgccaa gatgttggca ggtgatgatg tgacagaagc agccctgacg
     7801 caagccagag aattgttgag aaacagggag aaataagatg acagattatt atgtaattgg
     7861 agatgttcac ggaaaagctg ggatgctgga agaccttctt aaaacctggg atggtcagac
     7921 ccagttgctc tttctaggtg atttgattga cagaggtgag gatagtcacc gtgttcttga
     7981 aatggtcaag gacttggtgg acaatcaagg ggctatctgt ttgtctggaa accacgagta
     8041 tatgtttttg acttggctag atgacccaga agaaagttat gaccattatc gtcgcaatgg
     8101 tggagataca accattaact ctatcctagg tcgtcccttg gatgcaccag ttgatggagt
     8161 agaagatgcc aagcgggttg ccgctgaagc ggcagacttg gtcgaattca ttcgtcaaat
     8221 gccatttgta gtagagacag acaagtatat ctttgttcac gcaggtattg atttgacctt
     8281 ggatgactgg catgaaacaa cagattataa aaaagtatgg cttagaaaac cattccacgg
     8341 agctgaaaat catactggaa aaaccattgt cttcggtcat acaccggtct atggtttgtt
     8401 acagcaagaa cgcggtacat ctgagctttg gactacagaa gatggcaaga ttggaatgga
     8461 tggaggagct gtttatggtg gtgtccttca cgggattgtc tttacagacc aaggaatgac
     8521 agaacaccac tttatcgaaa atgacggctt tgtcgctgaa gattagtact cttagcaggg
     8581 tatggtcttg tcaaaatatc aaaaacaatt tataataaat agataccctg aaaggaagag
     8641 aatcatgaac ttagaagaat tgaaaaaacg acaggagaag atccgtaact tctctattat
     8701 cgcccatatt gaccacggaa aatcaactct agcagaccgc attttggaaa aaacagagac
     8761 ggtttcaagt cgtgaaatgc aggcccagct tttggatagc atggagctag agcgggaacg
     8821 tggaattact attaagttga atgccatcga gttgaattac actgcaaaag atggggaaac
     8881 ttatattttc cacttgattg acacaccagg gcacgttgac tttacctatg aagtttcacg
     8941 ttcgctagct gcctgtgagg gtgctatttt ggtggtcgat gcggctcaag gaattgaggc
     9001 tcaaactctt gccaacgttt atctggcttt ggataatgat ttggaaatca tgcctatcat
     9061 taataaaatt gacctgccgg ctgcagatcc ggagcgcgtg cgtacagaga ttgaagatgt
     9121 gattggtttg gatgccagtg aagcagtttt ggcttctgcc aaggctggta ttgggattga
     9181 agaaatcctc gagcaaattg tagaaaaagt accagcacca acgggtgatg tgacggcgcc
     9241 acttaaggcc ttgattttcg actctgttta cgatgcttac cgtggggtta tcctccaagt
     9301 acgtgtcatg gacggagtgg tcaaacctgg tgataagatt cagctcatga gcaatagtaa
     9361 gacctttgat gtgaccgaag tcggtatttt tacaccaaaa gcggttggtc gtgatttcct
     9421 tgcgactggt gatgttggtt acattgcggc gtctatcaag acggttcagg atactcgtgt
     9481 gggtgatacc gttaccttgg caaccaatcc tgcggcagaa ccattacatg gttataagca
     9541 gatgaatcct atggtctttg cgggtctcta cccaatcgaa tcaaacaagt acaatgacct
     9601 gcgtgaagcg cttgaaaaat tgcaactgaa tgatgctagt cttcagtttg aaccagaaac
     9661 atctcaggca cttggatttg gttttcgttg tggatttctt ggacttctcc atatggatgt
     9721 gatccaggaa cgtttagagc gtgagttcaa tattgacctc atcatgacag ctccgtctgt
     9781 tatttacaaa gttaatttga ccgacggtga gtctatggat gtgtctaacc catctgagtt
     9841 tccagaccca actaagattg cgaccattga agagccttat gtcaaggcgc aaatcatggt
     9901 accacaggag ttcgtcggag cagtaatgga gctagctcag cgtaagcgtg gggactttgt
     9961 gactatggac tatattgatg ataaccgtgt caatgttatc tatcaaattc ctcttgctga
    10021 aattgtcttt gacttctttg ataaacttaa gtcttcgaca cgtggttatg caagctttga
    10081 ctacgaattg tcagaatatc gcccatctaa gctggtgaaa atggatatcc ttctcaatgg
    10141 agataaggtg gatgccctca gctttatcgt tcacaaggac tttgcctacg aacgtgggaa
    10201 actcatcgtt gataaactca agaaaatcat ccctcgccaa caatttgaag ttccaatcca
    10261 agcggctatt ggacacaaga ttgtcgctcg tactgatatc aaggcccttc gtaagaacgt
    10321 acttgctaaa tgttatggtg gtgacgtttc tcgtaagcgt aaactccttg aaaaacaaaa
    10381 agctggtaag aaacgcatga aatccatcgg atcagttgaa gttccgcaag aagccttcct
    10441 cagcgtcttg agtatggatg aagaataagt tatcagaaat gcctttcctt gttcacagga
    10501 aatttatata agaatcaata gtaaagcagg cttagatggt ctgctttttt agtttttata
    10561 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtatgtat ggttactgac
    10621 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag ctgacttcgt cagtttcatc
    10681 tacaacctca aaaccatgtt t
//
LOCUS       DAVMCN010000059        10610 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVMCN010000059 DAVMCN010000000
VERSION     DAVMCN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.060"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..558
                     /locus_tag="VYP85_001728"
                     /pseudo
     CDS             1..558
                     /locus_tag="VYP85_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            458..904
                     /locus_tag="VYP85_001729"
     CDS             458..904
                     /locus_tag="VYP85_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1882207.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKKPIPKHLPPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1042..2346)
                     /gene="eno"
                     /locus_tag="VYP85_001730"
     CDS             complement(1042..2346)
                     /gene="eno"
                     /locus_tag="VYP85_001730"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1882208.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2510..2956
                     /locus_tag="VYP85_001731"
     CDS             2510..2956
                     /locus_tag="VYP85_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1882209.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2953..4068)
                     /locus_tag="VYP85_001732"
     CDS             complement(2953..4068)
                     /locus_tag="VYP85_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1882210.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4077..4406)
                     /locus_tag="VYP85_001733"
     CDS             complement(4077..4406)
                     /locus_tag="VYP85_001733"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV1882211.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4351..4722)
                     /locus_tag="VYP85_001734"
     CDS             complement(4351..4722)
                     /locus_tag="VYP85_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1882212.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4781..6214)
                     /gene="glgA"
                     /locus_tag="VYP85_001735"
     CDS             complement(4781..6214)
                     /gene="glgA"
                     /locus_tag="VYP85_001735"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1882213.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6211..7350)
                     /gene="glgD"
                     /locus_tag="VYP85_001736"
     CDS             complement(6211..7350)
                     /gene="glgD"
                     /locus_tag="VYP85_001736"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1882214.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7340..8482)
                     /locus_tag="VYP85_001737"
     CDS             complement(7340..8482)
                     /locus_tag="VYP85_001737"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1882215.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8472..10400)
                     /gene="glgB"
                     /locus_tag="VYP85_001738"
     CDS             complement(8472..10400)
                     /gene="glgB"
                     /locus_tag="VYP85_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1882216.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3233 a         2324 c         1881 g         3172 t
ORIGIN      
        1 ctatgggcta cactcgaaaa aaagaaccac acctactatg aacaagagcc agaaaaagta
       61 gccttatttc ttaagaattt taatagttta aagcacctag cacctgttta gattgatgaa
      121 acaggattcg atacttattt ttatcgagaa tatggtcgct cattaaaagg tcagttaata
      181 agaggtaaag tatctggaag aagatatcag aggatttctt tggttgcagg tctaacaaat
      241 ggtgagttaa tcgttccaat gacttacgaa gagacgatga cgagcgactt ttttgaagct
      301 tggtttcaga agtttctctt accaacatta accacaccat cggttattat tatggataat
      361 gcaagattcc atagaatggg taagttagaa cttttatgcg aggagtttgg tcataaactt
      421 ttacctcttc ctccctactc gcctgagtac aatcctattg agaaaacatg ggctcatatc
      481 aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct tttacgaggc tcttttgtcc
      541 tgctcttgtt tcaattgact atataaattg tctaagcgaa acaaccgata agaattggca
      601 caaaagcgac cgtatttttg ttaccaatat aggaaaacca gttcatagtt ctatcttgag
      661 caagtctctc cagcgagcaa acgaacgcct taaaaaacca attcccaaac atctgccccc
      721 tcacatcttc agacacacca ctattagcat cttatcagaa aataaaattc ctttaaaaac
      781 aatcacggac agggttggtc attccgactc tgaagtcact acttccatct acacccaggt
      841 cacaaagaat atgaaagatg aagcaatcaa tgtactggat aaagttatga aaaagatttt
      901 ttaaaaagtt ttgtcccttt tttgtcctct aaatacaaaa atagcccttc ggataaaatc
      961 cgaggggcta gaaacgttgt taaatcaacg gccgaacttt tgaatttcat ggttcgggat
     1021 aaaatagttc actgaactat tttatttttt aaggttgtag aatgatttca atccacgata
     1081 ttcagctact tcaccaagtt ggtcttcgat acgaagcaat tggttgtatt tagcgatgcg
     1141 gtctgtacgt gaaagtgaac cagtcttgat ttgtcctgcg ttagttgcaa ctgcaatatc
     1201 agcgattgtt gaatcttcag tttcacctga acggtgtgat acaacagcag tgtaaccagc
     1261 ttctttagcc atttcgatag cttcaaaagt ttcagtaaga gtaccgattt ggttaacttt
     1321 gataaggatt gagttagcag caccttcttg gataccacgt gcaaggtagt cagtgtttgt
     1381 tacgaagaag tcatcaccaa caagttgtac tttcttacca agacgttcag taagagcttt
     1441 ccaaccatcc cagtcgtttt catccatacc atcttcaata gtgatgattg ggtatttgtt
     1501 aaccaattct tcaaggtagt cgatttgttc tgcagatgta cgaacagcag caccttcacc
     1561 ttcaaattta gtgtagtcgt aaactttacg ttctttatcg tagaattctg atgaagcaca
     1621 gtcaaatccg ataaatacgt ctttacctgg tacatatcca gcagcttcaa tcgcagcaag
     1681 gatagtttca acaccatctt cagttccttc gaaacgagga gcgaatccac cttcgtcacc
     1741 tacggcagtt tccaaaccac gtgatttaag gattttctta agagcgtgga agatttcagc
     1801 accgtaacga agggcttctt taaatgttgg cgcaccaact ggcaagatca tgaactcttg
     1861 gaaagcgatt ggagcgtcag agtgagaacc accgttgatg atgttcatca ttggagttgg
     1921 aagaacttta gtgttgaatc caccaagata gctgtaaagt gggatttcaa ggtagtcagc
     1981 agcagcacga gctacagcga tagacacacc gaggattgca ttcgcaccca atttaccttt
     2041 gttaggagta ccgtcaagtg cgatcatagc acggtcaata gcttgttgat cacgtacatc
     2101 gtagccaatg atagcttcag caatgatgtt gtttacgttg tcaacagctt tttgtgtacc
     2161 aagaccaccg taacgagatt tgtcaccgtc gcgaagttca actgcttcgt gttcaccagt
     2221 agaagctcct gatggaacca taccacgtcc gaaagcacct gattcagtgt aaacttctac
     2281 ttcaagtgtt gggttaccgc gtgagtctag gacttcgcga gcgtaaacat cagtaataat
     2341 tgacattttt tactctcctt atgagttaaa ttttttacac ctctataata ccttaaaacc
     2401 cctccttttt caagaaaaaa cgttatcttt gtgcaacttt tccttaactt tataaagtaa
     2461 tcgctttctt ttgtctgttt tattctaact tttatgatat actgttttca tgacagattt
     2521 atcaaaacaa ttacttgaaa aagctcatgg tgggttaaaa ataaatccgg atgagcaaag
     2581 acgctatctt ggtacttttg aggaaagagt tcttggatat gtagatattg acacagcaaa
     2641 tagccctcag ttagaaaaag gctttttatt tattttagaa aaccttcagg aaaaagcaga
     2701 gccactattt gtgaagattt caccaactat cgaatttgat aagcaagttt tctacttaaa
     2761 agaagcaaaa gaaactgata gtcaagccac catagtatct gaagagcata ttacttctcc
     2821 ttttggcctg gttattcata gcaatgcacc agttcaagta gaagaaaaag accttcgact
     2881 tgcttttcca aaactttggg aagttaaaaa ggaagaacca gccaaaacat ccttatggaa
     2941 gaaatggttt agctaaatct tgcacatatt taataagtgc ccaatattgg cagccgtgcg
     3001 ctccagatag agactggcat ttttcaaact atcttctaaa ggttcacttt tctccaaaat
     3061 agaaaagaca gcttggatat tttcaaatgg taggggaggt aaatcttcag caagactacc
     3121 gcaaatagca ataacaggaa ctccaacagg ggttcttttt gcaacaccta taggcgcttt
     3181 cccagcaaag ctttgactgt caagtcttcc ttctccaaca acaaccaagt cagcatctga
     3241 aactttctta tcaaagttga ttaagtccaa gcaggtatca attccagaca cgatacttgc
     3301 ctgagcaaag gcacacaaac caccagcaag gcctccacct gctcctgctc ctttaatttc
     3361 taatgttgca ggtgagaatt tttcataaaa atcttggatc gcctgatcta cgactgcaaa
     3421 catagtcgga tgtagacctt tttgattgcc aaaagtgtaa gtcgcacctt gataaccaca
     3481 taagggactc acgacatctg ctaaaatatg aatttgaaca ccttcaggaa ttttatagcg
     3541 attttctgtt gaaacagaag ctaagtttaa taaggattga ccggaagcag gcaagacatt
     3601 tccatcccta tcataaaatt gataacctaa accagcagca atccccagtc ctccatcatt
     3661 actggccgtg ccaccaacac cgatataaat atctttaatc cctttagaaa tgagatggag
     3721 aatcaactct ccaataccac aagtttggat ttgaagtgga tttcgtttct ctagcggaat
     3781 ttttccaaga ccaaccaagt cagctacttc aaatagtgcc agttcccctt tttgaaaata
     3841 gcgcatggct tctttttgtc caaaagggtc tgtcacttgg atccattttt cttttaggtc
     3901 aagagaatgt cggatagcat ctacagtacc ttctccccca tcaccaacag ggcagaggag
     3961 acattctaca tctgctatcg attgttggaa gcctcttttt attgcttcag ctacctgttg
     4021 agctgtcaag ctttccttaa acgaatccgg tgcaattaca atcttcatat tttccctcat
     4081 tctaaacagt caatcaaagg aagaacttct aaaaaatccc tcttgtcaac atgatgtggt
     4141 atttcttttt tgagcacttc tttggcacaa aaggcgattc ctaactccgc cgacttcaac
     4201 attaatagat tattgacccc atcaccgatt gccaccgttc tttctttaga aagttttagt
     4261 ttctttctcc atttttccag agtttctttt ttgacctggg gacttataat ttgtccaact
     4321 aattttcctg ttaaaagacc ttctttgact tcaagctggt tggcagtgaa ataggcaata
     4381 ccaagggatt ttgctaatct ctccaactat tggtgtaaat ccaccagaca ccagaccaac
     4441 taggatgcca ttcttttgga gaatagagat gaactctggg acatttagcg atagatgaat
     4501 tgagttgaag acgttatcaa agaccaaaat aggaagacct tccaacaagg acactctttt
     4561 tcttaaactg ctttcaaaga ccaactctcc tcgcattgct cgacttgtaa tctgcgaaat
     4621 ttccgcctca tgacctgcct ctctccctaa aagatcaatc acttcttcta ggattaaggt
     4681 tccatctaca tccaaaacac acaagccttt tacttgagac atcagttctc ctctctaaac
     4741 agcctaaaaa tcgtatgaag tcatcatacg attttatcta ttaattaact aaactatggt
     4801 acaagtcaag gtatgacttg caggctgtat cccatgagaa gtcactctcc atagcttgtt
     4861 tttgtaggtt tctccaaatg tctggatggt ttctatacaa gtccaatgct gtttggaaag
     4921 tccaatttaa ccaataagga gatagattgt caaagctaaa gccagtaccg cttccttcga
     4981 ttggattgaa agcgcgaact gtatctcgca agcctccaac ttcatggacc aatggcaagg
     5041 ttccataacg catagccatc atttgagaca agccacacgg ttcaaaacga cttggcatga
     5101 ggaagaggtc acaagcagcg tagatttcct gagcaagttt gacatcaaaa gtgatatttg
     5161 ttgatagctt gtctgggtaa atctgagcaa accatgagaa agctccttca aaggctggat
     5221 cgccagttcc caaaagaaca atctgaacat cttcttgcaa gatatggtga agactttcga
     5281 ccaccacatc aaaacctttt tgacgtgtca aacgagaaac aattcccacc agtggaacgt
     5341 ctgctctaac aggcaagcca actctttctt gcaattttgc cttatttttg gctttcccag
     5401 acaaatcttc ctgattgaaa tgatagtcta aaagagcatc cgtctgagga ttataaagat
     5461 cagcatcaat cccattcacg ataccagata ctttaccaga ctccatttta agaatctgat
     5521 ccaaattaca tccaaactga ctagtcataa tttcatgagc atagctaggt gaaacggttg
     5581 aaacacggtt cgcatagaga atacctgcct tcatccagtt cagacagttg ttccatcgaa
     5641 gggtgccatc agcgtaacgt tcaaggccaa ctccaaacaa atcacccaac attccttctg
     5701 aaaattgtcc ttggaattct aaattatgaa tggttaaaac tgtttcaatg tcctcatagg
     5761 cttgaatcca acggtatttt tccttcaaca agaaaggaat catagctgta tggtagtcat
     5821 gaacatggag aagatcagga ataaagtcaa tcctttccat agcctcaatg gcagccagtt
     5881 ggaaaaaggc aaagcgttct ccgtcatcaa aatcaccgta aacatgacca cggaagaaat
     5941 aatattgatt gtcaataaag tagaaggtta caccatttaa tactgttttc ttaattccac
     6001 aatactgtct gcgccaacca acgctcacct caaaatgaag cacatcttca atctgatttc
     6061 caaatttagc ctctaccata tcatagtagg gtaaaatcac tgcaacttcg tgcccagctt
     6121 ttaccagtga ttttggaaga gcgccaatga cgtctcccaa accacctgtt tttgaaaaag
     6181 gtgcaccctc tgctgctaca aataaaattt tcatgaatga atatcctctg ttactttagc
     6241 acctttctta accacaactg gatgttctgc agttcctcga atcacaacac caggctcaac
     6301 ttcaacccct ttgtccaaga tagcatattc gacctgagcc ccttttccaa taacaacacg
     6361 agggaagagc aggctatctt taaccaagct atccttatgg acatgaatat tacgtgatag
     6421 aacagaatta gctacttgac cttcaataat actaccagag gcaaactgag aagtgcttac
     6481 cttagatgta ttagcatagt aagttggctc ttcgtttttg acctttgtat aaatcttttg
     6541 gtttggtgag aaaagagaat agaatttttg tgattcaagc atatcgatat tcgcttgata
     6601 ataagattta acagagtgaa tattggctag atagcccgtg tactcgtagg cgaaagctcc
     6661 ctcttttaca gccaaatccc gtaaaacata gcgcaatttc tttggatgtt cttttttagc
     6721 ttcttcttcc aagtgttcaa tcaaccaagg tgtatcaacg acaaagatat ctgtagacat
     6781 attgaacatt tcagctgttg acttgctatc aaagagttta tgagaaagaa catggtctgt
     6841 ttcatctaca tccaagattg catttacttc tgaaatatct ttcttagcta gttttttata
     6901 aactacagtg ataggctctt ttgttgtact atgtaggtgg aaaacttggt tcaaatcaat
     6961 gttaataaga acatcgcagt tgagggcaac cgtttggttt gagccagaac gtttcaaata
     7021 agtaagaagc tgttggtagt attcttttcc aactgtacta ctttctacac gggtattgta
     7081 aattcctaga tagtaatgac taagaagggt tgataagccc cactcgcgtc ctgaacgaat
     7141 atggtcaaat actgagctga tattatcctg ctggaaaata ccaaagacac tacgaacacc
     7201 tgcattagca aggcttgaaa gtgggaagtc aatcaaacga tatttcccac caaatggcaa
     7261 acttgctact ggacggtggt ccgtcaatgt cgacatattg tgaaaaccaa ctgtatttcc
     7321 taaaatggca gaatatttat caatcttcat ctgttgctac ccccactact tcattatatc
     7381 ctacaacttg tacttcatct gttccatcaa tttcgacacc gtcagaaata atcgcacctt
     7441 caccaataat ggcacgttta atcttagctc cttgaccaat gatagctcca ctcatgataa
     7501 ctgaatcaag gacttccgct ccttcgcgaa cttgcgcgcc tgttgaaagg atagaatgtt
     7561 taacagctcc atcaacgaaa catccgtcta caactaatga gtcttccaca tgagcatttg
     7621 ccccgaggaa gtttggtggt gaaatcaagt ttcttgagta aatcttccat tgacggttac
     7681 gactatccaa ggcattttct ggagaaatat actccatgtt cgcttcccaa agtgactcaa
     7741 tagtaccaac atctttccaa taaccactaa attcgtaagc ataaacactt tcacctgact
     7801 caaggtaatt tggaatgaca tttttaccaa agtctgacat gccaaccttg ctcttttcag
     7861 cagcgactaa catattacga aggcgttgcc aatcaaaaat gtagattccc atagaagctt
     7921 ttgtagattt aggttgagct ggtttttctt caaattcaac aatacgattg ttagcatctg
     7981 tgttcatgat accaaaacgg cttgcttctt taagagggac gtctaaaact gctactgtca
     8041 agctggcatt attatcctta tgagactgga gcatatcatc atagtccatt ttgtagatgt
     8101 ggtccccaga caaaatcaag acatactcag gattgacact gtcgatatag tcgatatttt
     8161 ggtaaatagc gtgactagtt ccctcaaacc aacgatttcc ttcacttgca gaataaggtt
     8221 gaagaataga gacgcctgaa ttaataccgt ctagtcccca gcttgaacca ttcccaatat
     8281 ggttgttgag agcaagtggt tgatactgtg taacgacccc aacattatga atccctgagt
     8341 tggcacagtt tgatagggca aagtcaatga tacggtagcg cccaccaaat tgcacagctg
     8401 gttttgcgat gctttgagtg agtttaccga gacgagttcc ttgcccacca gcaagaatca
     8461 aagctaacat tttatttttc attttctact cctttttggt ttttatttgt gacggtttta
     8521 gtagatttca agcgacgttt gattttccat acacttgctc ccatagccgg tagagtaaag
     8581 gttaaggtct gctcataatc tttccatagg ccttcttgcg tttgaacagt ttgattatgt
     8641 tctttccaaa cgcctcccca ctcttccaac tcagtattcc atacttcttc gtaaattcct
     8701 gcaacgggta gtccgattgt aaaatctttc cgctcaacag gtaccatgtt aaagatacag
     8761 actaacattt ctcccttttt acccttacga ataaaggaaa gaacactctg gtctcgatta
     8821 tccgcatcaa tgatttcaat accatcatag ctggtatcga tttcccacag acagcgatga
     8881 tctttgtaaa actggtttag ctgagaagtg aaatacttca tcttagcatt cattgggtct
     8941 tctaggttag accattccaa ctgttcttca gatttccatt ctaggaattg accgtattcg
     9001 ctacccatga agagcaattt cttaccaggg tgacaaattt ggtacgtata gagattgcgc
     9061 aagcctgcga attgattgta acgatctccc cacatcttat gcatcatact cttcttgcca
     9121 tgaaccactt catcgtgcga gaatggcaag agataattct ccttgaaaac atacataaag
     9181 ctgaaagtca ccaggttaaa gtcatattta cgataaatcg gatcttcttc gtagaaacgg
     9241 aggatatcat tcatccagcc catgttccat ttgtagtcaa atcctagacc accaatctct
     9301 ttcattcccg taatcttggt cgcagacgaa ctttcttctg caatcatcat cacatctgga
     9361 tattctaact taataacttc attcaagcgt tgaagaaaat aataaccttc atagttaaga
     9421 tttccgccat ctttattagg tgtccatgga gcattatcat agtccaaata gagcatgttg
     9481 ctaacagcat ccacacgaat accatccaaa tgatagacat caatccaatg cttaatgcaa
     9541 gaaattaaga aggactggac ttcatttttt ccaaggtcaa aattaagggc accccaacca
     9601 tggttatgag ccttattatg gtcttggtat tcaaaagtcg gtgtcccatc ataataggct
     9661 aaggcatcat cgttgatggt aaagtgacct ggtacccagt ccacaataac cccaatatta
     9721 tgggtatgac actcctcgac aaaatcttga aactcctctg gtctgccata agcatgctct
     9781 aaagcgaagt aacccataag ctgatacccc caactcaagc ccaaaggatg ggacatcaag
     9841 ggcataaact caatatgagt atagttcatt tcaacgagat aaggaatgag ttcatccttg
     9901 agctgggcaa aactataagg actgccatca ggatttctct tccaagagcc agcatgaacc
     9961 tcgtaaatat tgacaggacg ttcaacaaag ccccaacgtt ttcttcgtgc cagccaaagt
    10021 ccatccctcc atttcttatc aggaagctct gttacgattg cccctgttcc tggacgagcc
    10081 tcatacctga cagcaaaagg gtcaatcttc atcagttgat gaccattttg acgtgtgaca
    10141 tgatatttgt aaatatgccc ttcttgagcc atattggtaa agacttccca gaccccaaag
    10201 tcatttctta ccattggaat ctgattttca atccagttgg taaaatcacc aaccaagtga
    10261 acagcctgag cattaggtgc ccaaacacgg aaggtatagc catgctctcc atttagttct
    10321 tccctatgtg ctcctagata atgttggaga taaaaatttt cacccgtcat aaaggttttt
    10381 aatgcttctc tattatccat atactcccct tctcctgtaa gcgttttcta tgtttttatt
    10441 atactacctt tttagagaag attcaagtaa attactatac ttctttaatt attttgaaaa
    10501 tctacaacaa gttcacttac tcgttcaatt gtaaatcaat attttttcaa aaaattgcga
    10561 aaacgccttt ctttttctac tatagtgaaa tgaaataaaa catgcgcaaa
//
LOCUS       DAVMCN010000060        10587 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVMCN010000060 DAVMCN010000000
VERSION     DAVMCN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.061"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            2..616
                     /locus_tag="VYP85_001739"
     CDS             2..616
                     /locus_tag="VYP85_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882217.1"
                     /translation="MKLKKTCVFQNLNFSCKQGEIIGITGANGSGKSVLFKLIAGLYS
                     PSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLASIRGVVGNQEIN
                     DTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMNALDKSSVENMR
                     TLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(696..1561)
                     /locus_tag="VYP85_001740"
                     /pseudo
     CDS             complement(696..1561)
                     /locus_tag="VYP85_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(1573..2335)
                     /locus_tag="VYP85_001741"
                     /pseudo
     CDS             complement(1573..2335)
                     /locus_tag="VYP85_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(2336..2623)
                     /locus_tag="VYP85_001742"
     CDS             complement(2336..2623)
                     /locus_tag="VYP85_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1882218.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(2633..3013)
                     /locus_tag="VYP85_001743"
     CDS             complement(2633..3013)
                     /locus_tag="VYP85_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1882219.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(2973..3653)
                     /locus_tag="VYP85_001744"
     CDS             complement(2973..3653)
                     /locus_tag="VYP85_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1882220.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATTYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVELPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            3869..4015
                     /locus_tag="VYP85_001745"
     CDS             3869..4015
                     /locus_tag="VYP85_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1882221.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVISKAAFGYIASGAEDTF
                     TSFQ"
     gene            4143..5633
                     /gene="lysS"
                     /locus_tag="VYP85_001746"
     CDS             4143..5633
                     /gene="lysS"
                     /locus_tag="VYP85_001746"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1882222.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            6258..7394
                     /gene="lctO"
                     /locus_tag="VYP85_001747"
     CDS             6258..7394
                     /gene="lctO"
                     /locus_tag="VYP85_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1882223.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      7646..7734
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7949..8617
                     /locus_tag="VYP85_001748"
     CDS             7949..8617
                     /locus_tag="VYP85_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1882224.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(8767..8853)
                     /locus_tag="VYP85_001749"
                     /pseudo
     CDS             complement(8767..8853)
                     /locus_tag="VYP85_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8944..9726
                     /gene="thiM"
                     /locus_tag="VYP85_001750"
     CDS             8944..9726
                     /gene="thiM"
                     /locus_tag="VYP85_001750"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1882225.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            9728..10357
                     /locus_tag="VYP85_001751"
     CDS             9728..10357
                     /locus_tag="VYP85_001751"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1882226.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
BASE COUNT         3314 a         1855 c         2286 g         3132 t
ORIGIN      
        1 gttgaaatta aaaaaaacat gtgtttttca aaaccttaat tttagttgta aacaggggga
       61 aattatagga attactggtg cgaatggctc aggtaaaagt gtattgttta aattaatagc
      121 tggtttatat agtccgtctt atggagaagt gttaatcaat ggggaaaata ttgttcctga
      181 gagaaaaatt ccagctaatt tgggagcttt gattgaagaa cctggtttta taaattatta
      241 tagtggcttt aagaatttac aatatttggc aagcatacga ggagtagttg gtaatcagga
      301 aatcaatgat acactgaaaa tagttggtct atatgagcaa aaagaccaga aagttaaaac
      361 ttattcgcta ggtatgagga aaaagctagg gattgctcaa gcaattatgg agaatccctc
      421 tattctttta ctagatgaac ctatgaatgc cttggataaa tcaagtgtag aaaatatgag
      481 aacattgttt agaaagctct ctagtgaaaa agggacaaca attttgattg ctagtcatag
      541 tgaagaggat attcgtatct tatgtgataa agtatatgca atagaagata aagtatgtac
      601 actgtgttca gattgaacat cttagataga ctcaggatgt tataggtaaa atcttaaaaa
      661 gggattggag cttaaaatcc agtccctttt aagagttaat ggccaccttc aacaaccagg
      721 tcatctgctt tagcagcgtc accgtaggtt gggtgaagtg ttttttcata ggccttgtgg
      781 aagaagtttt ccttgcctaa tttttcaata tctttattga tgaagtctag caattcttgg
      841 ttgccttttt gaactgctgc cgcaatggta tcgggatcac cgagggaagt aattcctact
      901 tcaaatcctt tattttcaag tgcccaagct agaacttccg tattgtcagt tgaaaaggca
      961 tctccacgtc cgtcaagaag agcttggtaa gagtcactgt attggtcgta tttttggagt
     1021 ttgatttctg gatgattctt ttcaaaataa gtctcagcag tcgttccttt tgtgacaatt
     1081 aaggttttac cttcaagttg tttgacgtct gtaatgagac cagtcttagg tgatacgaca
     1141 cccagagaaa ctttcatata tggaagggca aaatcaactt gtttcttacg ttcgtcagtt
     1201 actgtaaagt tagcaagagt aatatctacc ttgtttgaaa tcaagtattc cgcacggttg
     1261 gcagcatcga ctgaaatgta tttaaccttg acaccaaggt cttgagctag ttggttccct
     1321 agttcaatat cgtagcgtag ccttggtaag aaccatcatt gtcaacgtag ccaaacggtt
     1381 ttttatctcc aaacacggcg attcgcagtt caccgctttt tttgatttca tcgatagtgc
     1441 gagctttggc agttgttttt ccagaggatg aaccagcgtt tccacctgag ctacaagcag
     1501 tgataaagat aagggcaaag gcaagtgcta aaacagttaa gagtggtttg aatagtttca
     1561 taagaatctc ctttatagat atgagccgaa ttggctaaag tcaaagacgt ttaaaaattc
     1621 ctgggctcgt ttggtttgcg gattggtaaa gaaggcttga gctgttcctt cttcagcgat
     1681 tttcccttgg tcgaggaaga taatccggtc agtaatggct tgggcaaact gcatttcgtg
     1741 ggttactaaa atcatggtac ggccttcttg ggccaaatca ttgataagtt ccagcacctc
     1801 acgcaccatt tctggatcca gcgaagcagt cacctcgtca aaaaggatga tttctggatg
     1861 cattaggagg gcacgggcaa ttgcaacacg ttgcttctgt ccaccagata attgacgggc
     1921 aaagcaaagc tatgttgttt atccagcaaa tcgacacgat ctagtaattg caaagcttct
     1981 tccgttactt ctttcttgtc ccttccttga gttttgatag ggcctaggat gaggttttgt
     2041 aagacatcca gatggggaaa gagttcataa ctttgaaaga ccatgccaat cttttggcga
     2101 actaggtgaa aatctttttt attttcaacg atagactgac catccagaaa aatatctcca
     2161 ccttgaatac tttctaagcc gttgaggcaa cgaaggaggg tacttttccc acaaccagat
     2221 ggccccagga tgacaacaac ttcccttttt tgatttctag agaaagtcct tggaggatgg
     2281 gattgtctcc gaaggatttt tttagttcct tgatttctaa gatagtttca gacatttagt
     2341 ttctccaatg tttttctaag tgagtggata gtttggaaat agggtagcaa actgcgaaat
     2401 ataagactag aatggttcca taaatccaaa atgaagcagt tgggatggtc aggcgattgc
     2461 tatcgatgat ttgttgtcca actttggtca cttccacaac cccaatcaaa acaactaatg
     2521 aagtggtttt aatcatccga gtgacaagat tgatagcctg cggtagcagt cttcttaaga
     2581 cttgtgggat gatgatgtgg tagtaaagtt gaacattagt caagtcgagt gcctatccac
     2641 tttcaaactg atgtttaggg agagaagtga tagctccacg taccaagtct cccatttcag
     2701 ctgttcccca gagggtaaaa atgataatag ctgaagtctc acctgagata ttgatattaa
     2761 agtttcgagc caagccaaag taaacgatga agagtagcac cagctggggc atgatacgga
     2821 taaattccag atacaatcgt gttaaaaatc gtatgattct agaatgggag gtcatgatga
     2881 ttcccatgac tgttccgaac atcatggata agaggacaga caggatggat atcccaatcg
     2941 taacgcccaa cccctgtaag attctcagga gattatttcc ttgaaagagt acttggattc
     3001 ccgaatcctg catggcgggt cctcctttct atccagctaa agaccagtga gatgggtagc
     3061 agcatgatca gataagcaac taccaacata gctagcgcaa tgtctgtctc atagtagaga
     3121 ccaatcaaat ccttggcgac gtacatgagg tcggccaaag ccactgctga gaaaacagag
     3181 gtttccttga taaggaaaat gacattggca ctaaaggagg ggagttccac cgctgttgct
     3241 tgcggaagaa ccacatagcg aaagacctgt agaggtgtca gaccaatagc gaggccaatc
     3301 tcctgctggg tttgactgat ggcttccagc ccacttcgga aagattctgc catataggag
     3361 cctcctaaaa agacaagccc aagcgttgca cagacttctg aagataggac aatcccgatt
     3421 cggggaagac cgaagtagag aaagaagagt tgaatcaaaa ggggcgtatt acgtgacaat
     3481 tcaatgtagg ttgtcgctac ttgcgccaaa acagggattc gataatgtcg gatgatacta
     3541 acgattaaac cgagcagaaa ggatcccaaa attccccaaa ctgcaatatg caaggtcaga
     3601 aagaatgcct tttgatatag tggtagatat tgttcaacaa tggaccaatc caaaaataga
     3661 acctcccatc tagaaataat acagttattg tagcacttaa aatcttcttt ggataatatc
     3721 tattttttat tgccgttata aggatttttt accatagaca taaaatttct gaaatttcca
     3781 aacaaaatat ttgaaaagtt ttgaaaaaag agttaagata tttttataat atacaaagta
     3841 aacgcttact tatcaaggag ggcattttat gtcatacaaa acaagtaatg cagaaggtca
     3901 tgtagatttc atcaatacct atgatttgga gccaatggcg caacaagtta tttctaaagc
     3961 agcatttggc tatatcgcta gtggggcgga agatactttc acttcttttc agtgatttta
     4021 gcgtcaggtt ctttttagtt tttaaagatt atccgtgaat ttcttgctta tttatgataa
     4081 aatgggggta tcgcaaaaaa tgactcatcg tattcaattt tgagtaaaac taggaggatc
     4141 ccatgtctac agaacatatg gaagaactaa atgaccagca gatcgttcgc cgtgaaaaaa
     4201 tggctgcgct ccgcgaacaa ggaatcgatc ctttcggaaa acgttttgaa cgtactgcaa
     4261 attcacaaga attaaaagat aaatatgcca acctcgataa agaacaatta cacgataaaa
     4321 acgaaacagc tactatcgca ggacgcttgg taaccaaacg tggtaaagga aaagttggtt
     4381 ttgcccacct tcaagaccgc gaaggccaga ttcagatcta cgttcgtaag gatgctgtcg
     4441 gtgaagaaaa ctacgaaatc ttcaaaaaag cagatcttgg tgacttcctt ggtgtcgaag
     4501 gtgaagtgat gcgcacggat atgggagaac tctctatcaa ggcaacccac atcacacact
     4561 tgtctaaggc tcttcgtcct cttcctgaga aattccatgg tttgacagac gttgaaacaa
     4621 tttaccgtaa acgttacctt gacttgattt ctaaccgtga aagctttgaa cgctttgtca
     4681 ctcgttcaaa aatcatctct gaaatccgtc gttaccttga ccaaaaagga ttccttgaag
     4741 tggaaacacc tgttcttcat aatgaagccg gtggtgctgc tgcccgtcca tttatcaccc
     4801 accacaatgc ccaaaacatt gacatggtgc ttcgtatcgc gactgagctt cacttgaaac
     4861 gccttattgt gggtggtatg gaacgtgtct atgaaattgg ccgtatcttc cgtaacgaag
     4921 gaatggacgc tactcataac cctgagttca cttctatcga agtttaccaa gcttatgcag
     4981 acttccaaga catcatggac ttgacggaag gcattatcca acatgctgct aaatcagtca
     5041 aaggtgatgg cccagtcaac taccaaggta ctgaaatcaa gattaacgaa ccatttaagc
     5101 gtgttcatat ggtggatgct atcagagaaa ttactggtgt cgatttctgg caagacatga
     5161 ctttggaaga agctaaagct atcgctgctg agaagaaagt tccagttgag aaacactaca
     5221 ctgaggttgg tcacatcatc aatgccttct ttgaagagtt tgttgaagaa actttaatcc
     5281 aaccaacctt tgtctatgga catccagtag ctgtatctcc actcgctaag aaaaatcctg
     5341 aagaccaacg ctttactgac cgtttcgagc tctttatcat gactaaggag tacggtaatg
     5401 cctttactga gctcaacgac ccaatcgacc aacttagccg ttttgaagcc caagctaaag
     5461 ccaaagaact tggtgatgat gaagcgacag gaatcgacta tgactacatt gaagctcttg
     5521 aatacggtat gccaccaaca ggtggtttgg gaatcggtat cgaccgtctc tgcatgctcc
     5581 tcactgatac aacaactatc cgtgatgtat tgctcttccc aacaatgaaa taaattttta
     5641 tcctctggct cttaccagag gattttttga ttcaaaaaga gactgaattt aaggagaaaa
     5701 tgaagtgtag tatattgaag ttgaaatagt acactttgat ttctaagaca ttgttagaaa
     5761 ttggtttaaa ttccctaatc aatttgtgca tgttttattt cattttacga tagtacgctg
     5821 aaactgttca aaaagtacta gaaattgact tggattcccc aattgatttg ttcagattca
     5881 ctataaataa aaaattaata agtgggatag gaagttagcg tcaactagga tagtatcttg
     5941 cttaaacagt atatatggga ctgatataag tccataggtc ctattagagg atgttctggt
     6001 gtcttattca cttgtttttt tatagtatta gtagatagaa tcagcaaata aaaaagtagt
     6061 tcaaatgcct ggaagcaaaa aatctcaacg attcacttaa tatagactaa ggtttagagt
     6121 ttaaggaaag tagggctagt atattgtatg aaaaaataag atggttttta agcaaaactc
     6181 ttgaaaatga ttgaaaaaag agttattata gttgtatagt aaaaagcaaa cgcttactta
     6241 atcaaggagg gcattttatg tcatacaaaa caagcaatgc agaaggtcat gtagacttca
     6301 tcaataccta tgatttggag ccaatggcgc aacaagttat tcctaaagca gcatttggct
     6361 atatcgctag tggggcggaa gatactttca ctttaagaga gaatatccgc gcctttaacc
     6421 acaaactcat cgttcctcat acactttgcg atgttgaaaa tccaagtaca gagattgaat
     6481 ttgcaggtga aaaactatct tcaccaatca ttatggcgcc tgttgcggcc cataaattag
     6541 cgaatgaaca gggggaagtg gcgactgcgc gtggtgtgca tgagtttggt tctctttata
     6601 caaccagttc ttactctact gttgaccttc cagagatttc tgaagccctt caagggacac
     6661 ctcattggtt tcaattttac tttagtaagg atgacggtat caaccgccac atcatggacc
     6721 gtgtgaaggc tgaaggttat aaagcgattg tcttgacggc agatgctact gtagggggga
     6781 atcgtgaagt ggataagcgt aatggttttg tcttcccagt tggcatgccg attgttgaag
     6841 aatacctgcc agaaggtgct ggtaaatcaa tggactttgt ttacaaatca gctaaacaac
     6901 gcttgtctcc acgcgatgta gaatttatcg ctgaatactc tggtcttcct gtgtatgtca
     6961 agggaccaca atgccgtgag gacgttgaac gttcgcttgc tgcaggagct tctggtatct
     7021 gggtaaccaa ccacggtggt cgtcaaatcg acggtggacc agctgccttt gactcgcttc
     7081 aagaagtggc agaagcagtt gatagacgtg tgccgattgt ctttgactct ggtgttcgtc
     7141 gtggtcaaca cgtctttaaa gccttggctt caggagcaga cttggtagct attggtcgcc
     7201 ctgttattta tggcttggct ctcggtggta gtgtcggtgt gcgtcaagtc tttgaacact
     7261 tgaatgcgga attgaagaca gttatgcaat tgtctggagc tcagaccatt gaagatgtca
     7321 aacactttaa gctccgtcac aatccataca acccaacctt cccagttgac cctcgtgact
     7381 taaaattgta ttgataaaac agattgcctc cactgaatgt ggaggttttt cttcgtgtat
     7441 tggaagaata aattgctatc gaaaactata gtaaaatgaa ataagaatag gacaaatcaa
     7501 tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt
     7561 tcaatctact atataaagat atttttcggt caaatatctt gctagggctt tcattttttg
     7621 ctatactggt tcagtaatta aataatagag acatttgggg tgctttaagc tgagatgata
     7681 cccattgaac ctgatacagt taagactggc gaagggaaat gtgaaacgtt ttttcgtatg
     7741 gcgaaatgaa cgatctaatc ttgtaagtca actctaattc ttgattgtaa ttggagtttt
     7801 ttgtttatat aaactggata ggcttgttta gttagctctc tgcaaatgct ctcgatgtgc
     7861 tttaaaagga tcaagtggaa ttacgatttt gcttgatatt tcttggtgtt ttattaatta
     7921 ctaacaagta aagagaggag aagtaaatat ggaaacacaa gactatgcat ttcagccagg
     7981 tttgactgtt ggagaattat taaaaagcag tcagaaggat tggcaggctg caatcaatca
     8041 tcgttttgtt aaggaacttt ttgcggggac aattgagaat aaggtcttaa aggactatct
     8101 gattcaagat tatcacttct ttgatgcctt cttatccatg ctgggtgcct gcgtagctca
     8161 cgcagataaa cttgaatcca agcttcgttt tgccaagcaa ctaggctttc ttgaagcaga
     8221 tgaagatggt tatttccaaa aggcttttaa agagttaaaa gtagcagaga atgactatct
     8281 agaagtgact ttgcaccctg taacaaaagc ctttcaggat ctaatgtatt cggcagtggc
     8341 ttcatcagac tatgcccatc ttttggttat gctggtcatt gcagaaggtc tctatttaga
     8401 ctggggttct aaagatttgg ctctacctga agtctatatt cattcggaat ggatcaatct
     8461 ccacagaggt cctttctttg cagagtgggt tcaatttctg gttgacgaac tcaatcgtgt
     8521 cggtaaaaat cgagaagatt tgacagaact tcagcaacgc tggaatcaag cagtcgcttt
     8581 agaattagct ttttttgata ttggttacga tgtctagaga aggctcatga tatttacaaa
     8641 tttgatgagg taatactctt cgaaaatctc ttcaaaccac gtcagtttca ccttgccgta
     8701 ggtatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagctgac
     8761 ttcgtcagtc ttatctacag gctcaaagca gtgttttgag caacctgcgg ttagcctcct
     8821 agtttgctct ttgattttca ttgagtataa atcattcaac gtaaatgaaa aaaatttctt
     8881 aacgaaagat agagataaat cgaaatcagt agatcgtata aagtgtaaag gaaggatttc
     8941 aatatgacaa gtttaaaatt attaaaagaa aaagcaccat tggtcatttg tatcaccaat
     9001 gatgtagtaa aaaatttcac agcaaatgga ttagtagcac tgagcgtctc accagccatg
     9061 agtgagtttc cagcagattt agaggatttg ttaaagtatg ctggtggttt attaataaac
     9121 ataggaacat tgacagatga aaattggaaa ttataccaag ctgctctgaa aattgcggag
     9181 aaatataatg tcccagcagt tttagatcct gtagcctgtg gagcaggaga atatagaaaa
     9241 aaagtagcag atgatctaat caacaattat aaactagcag cgattagagg aaatgctggc
     9301 gagattgcct ctttagtagg aatagatgtg gcatctaaag gagtagatag tgcgggcgta
     9361 gataatattg acgaaattgc tctagcagca aatgagaagt tcaatattcc aatagtagta
     9421 acaggtgaag tggatgccat tgctgttaat ggagaagtgg taacgattca taatggtagt
     9481 gctatgatgc cgaaagtcat tgggacagga tgcttattag gagctgtagt agcaagcttt
     9541 atcggactag aaaaaggtca agaattgaaa tcattagaaa cagcaatgtt ggtttacaat
     9601 atcgctggag aaatggcaga aaaacgtcca aatggacatc ttcctgggac atttaaagtt
     9661 gaatttataa atgccttata cgagattaca gatgaagatg taaaggaatt caaaagagtg
     9721 aagtaagatg tttcataaag aattactaaa actatatttt atttgtggaa cgactacttg
     9781 ccaaggaaaa aatctatata cagtcgttga ggaagcctta aaaggtggta taaccttatt
     9841 tcaatttcga gaaaaaggtg agggtgcttt agaaggctta gaaaaacttg agctagctat
     9901 ccaaattaaa gaactttgta aaaaatacaa tgttccattt atcgttaatg acgatataga
     9961 tttagcaatg gaaattgacg ctgatggcgt acatgtaggt caagatgata ttggtgttga
    10021 tgaaattaga aaattgatgc cagataaaat aattggtctt tctataaaaa acgaggaaga
    10081 atttcaacaa tcaaaagttg aatatgtaga ttatgttggt gttgggcctg tatttgatac
    10141 ccagtcaaag gatgatgctg gtggtgctat aggttatgaa ggtgttaaat tgatgagaaa
    10201 actgttgcca caaatgccct tagttgcaat tggtgggata cagacgaaac atattaaaga
    10261 cattataaag accaatatgg atggcgtttc aatcatttcg gcaatatcgt atgcaaaaaa
    10321 tatagaaaaa actgttcggg aaatgagtga acaatagata tctatccttg gattctaagt
    10381 aagtaggatt ttcctttttt aaaaagctat gtctagattc agcttgaatg gctaattcat
    10441 caaacaggtc atttgttttt tgcaaaagaa agatctgctg tctttgtgag tgcaaggctg
    10501 tatttccagt tcaatttctt gaactagtat aaaatgtgtg ttataataat cacataatta
    10561 aataataaag gcatttgggg tgcttta
//
LOCUS       DAVMCN010000061        10190 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVMCN010000061 DAVMCN010000000
VERSION     DAVMCN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.062"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="VYP85_001752"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="VYP85_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1882227.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYVQANLDSSQD"
     gene            1317..2021
                     /locus_tag="VYP85_001753"
     CDS             1317..2021
                     /locus_tag="VYP85_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1882228.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="VYP85_001754"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="VYP85_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1882229.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRIRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="VYP85_001755"
     CDS             3365..4174
                     /locus_tag="VYP85_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1882230.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /locus_tag="VYP85_001756"
     CDS             4265..4507
                     /locus_tag="VYP85_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1882231.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="VYP85_001757"
     CDS             4509..4763
                     /locus_tag="VYP85_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1882232.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5583
                     /locus_tag="VYP85_001758"
     CDS             4810..5583
                     /locus_tag="VYP85_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV1882233.1"
                     /translation="MKKKWFFVDYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5831..6817)
                     /locus_tag="VYP85_001759"
     CDS             complement(5831..6817)
                     /locus_tag="VYP85_001759"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1882234.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7011..9479
                     /gene="gyrA"
                     /locus_tag="VYP85_001760"
     CDS             7011..9479
                     /gene="gyrA"
                     /locus_tag="VYP85_001760"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1882235.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9479..>10190
                     /gene="srtA"
                     /locus_tag="VYP85_001761"
     CDS             9479..>10190
                     /gene="srtA"
                     /locus_tag="VYP85_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1882236.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILT"
BASE COUNT         3151 a         1724 c         2283 g         3032 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgt ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggtcccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg tacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tgggcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg aattcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgaaaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcatctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggaaaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgcttcctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtggat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg caagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaactt ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgac aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagaaatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaagacccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tattgtacaa attgtagatg atgaattagt cgttgctact ctagaagttg
     4741 gtcatcggag agatatttat taaattaaag ctgagtaata acagtataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggtttttt gtagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgat tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttggctattc tccctttaaa tgctattttt acagtgtttc gattagggcg tatctttcgt
     5101 ttagctaaac taacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaattag aaagaaaaat tagtagattc ttacggacaa atggcctgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg atatggggat
     5341 attgttcctg cttccatttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgttaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actccaagat gaattatcta gtcagagaat attactagag
     5521 aaacaatcta aaaagataga agaactacat aaaatgatac aagatttgat tgaaaaaaca
     5581 taataaaaat aaagatgaga caaagtttga gctgaggaga aatcaagtaa gttttgacac
     5641 aatagaacgc atattatcag gtataaaaac ttgatactat gcgttttata gagaaataaa
     5701 ataaaatctg aacaaatcaa ttaggaattt aaagcatttt ataacaacgt tttagagtaa
     5761 cggggtacta tttcatataa tacaggaaaa aacaactccc tgatgattca aggagttgtc
     5821 tatagttaaa ttagttttta gaagcttctt ggaattctgg atttttccat gcttcgtcaa
     5881 taatagcttg caattcttta gcagatgctt gcattttttg agtttctgca tcgttcaatg
     5941 gaatgtttac tggacgaacg ataccatgtg caccaacaac agctggttga ccgataaaga
     6001 cattctcaac tccgtattga ccttcttgga atactgaaag tggaagtact gcgttttcat
     6061 cgtcaaggat tgctttagtg atacgagcaa gggctactgc gataccgtag tatgttgcac
     6121 cttttttgtt gatgattgtg taggctgcat cacgaacacc ttcgaacaat tcaatcaatt
     6181 cagcttcttg aacattttga gtatctttaa ggaattcttc aaggtttaca ccagcgatgt
     6241 tagcgtgcga ccaaacagcg aactcagagt caccgtgttc acccatgatg taggcgtgaa
     6301 ctgaacgagc atctacgtcc aatttttcag caagtgcttg acggaaacga gctgagtcaa
     6361 gtgaagtacc tgaaccgata acgcgttctt tagggaaacc agagaatttc caagttgagt
     6421 aagtcaaaac gtcaactggg ttagcagcaa caaggaagat acctttgaaa cctgattcaa
     6481 caacttgagt tacgattgat ttgttgatag caaggttttt acctacaagg tcaagacgag
     6541 tttcacctgg tttttgaggt gcacctgcag tgatcacaac aaggtcagcg tctgcacagt
     6601 cagagtattg agctgcatag atttttttag gtgaagtgaa ggcaagggcg tgactaaggt
     6661 caagcgcatc accaacagct ttttcatgca attgtggaat ttcgataatt ccaagctctt
     6721 gtgcaattcc ttggttaaca agtgcaaaag cgtaagatga acctacagca ccatcaccga
     6781 caaggataac ttttttgtgt tgtttagttg aagtcattgt tttaaacatc tccttaattt
     6841 tattagggga ttttccctag acaacttcat tctatcactt ttaaaaaact ttgtcacgaa
     6901 tatgccttat agttctcgat gtaaacgttt tagtggttta gaggctgaaa tagatgggaa
     6961 tttatggtat aatgttgtta cttactaatt gtgaaatgag gcatttatta atgcaggata
     7021 aaaatttagt gaatgtcaat ctgacaaagg agatgaaggc aagttttatc gactacgcca
     7081 tgagtgttat cgtagcgcga gctcttcctg atgttcgaga tggcttaaaa cctgttcacc
     7141 gtcgcattct ctacggaatg aatgaattgg gtgtgacccc agacaaaccc cataaaaaat
     7201 ctgctcgtat tacaggggat gtcatgggta aatatcaccc acacggggat tcctctattt
     7261 atgaagccat ggtccgtatg gctcaatggt ggagctaccg ttacatgctt gtagatggtc
     7321 atgggaattt tggttccatg gatggagata gtgctgccgc tcaacgttat accgaggcac
     7381 gtatgagcaa gattgctctg gaaatgcttc gtgatatcaa caaaaataca gttgatttcg
     7441 ttgataacta tgatgccaat gaacgggaac ccttggtctt gccagcgcgt tttccaaacc
     7501 ttttggttaa tggagcaact ggtatcgcgg ttgggatggc aaccaatatt ccacctcata
     7561 atctgggtga aaccattgat gcagtgaagt tggtcatgga taatcctgaa gtgactacca
     7621 aggacttgat ggaagtcttg cctggaccag attttccaac tggtgctctt gtcatgggga
     7681 aatcaggtat ccataaggct tatgaaacag gtaaaggttc gattgtccta cgttctcgta
     7741 cagagattga aacgactaag actggtcgtg agcgtatcgt tgtaacagaa tttccttaca
     7801 tggtcaataa aaccaaggtg catgagcata ttgttcgctt ggttcaggaa aaacgcattg
     7861 agggtatcac agcagtacgt gatgagtcaa accgtgaagg tgttcgattt gttattgaag
     7921 tcaagcgcga cgcctcagcc aatgttattc tcaataacct cttcaaaatg acccaaatgc
     7981 aaaccaattt tggtttcaat atgctcgcta tccaaaatgg tataccgaaa attttgtctc
     8041 ttcgtcagat tttggatgct tatatcgagc accaaaaaga agtggttgtt cgtcgtacac
     8101 gttttgataa ggaaaaagcg gaagcgcgcg ctcatatctt agaaggtctc ttgattgcgc
     8161 tagaccatat cgacgaagtg attcgtatca tccgtgctag tgaaacggat gcggaagctc
     8221 aagctgagtt gatgagcaag tttaagcttt ctgaacgtca aagtcaagct atccttgata
     8281 tgcgtcttcg tcgtttgaca ggtttggaac gcgataagat tcaatctgag tatgatgacc
     8341 tcttggctct gattgcggat ttagcagata ttcttgctaa gcctgaacgt gtttctcaaa
     8401 ttatcaaaga cgaattggat gaagttaaac gtaaattttc tgataaacgc cgtacagagt
     8461 tgatggttgg acagatcttg agtctcgagg atgaggactt gattgaagaa tcggatgtct
     8521 tgattaccct ttctaacaga ggctacatta agcgtttgga tcaggacgag ttcactgctc
     8581 aaaaacgtgg gggtcgtggt gtccaaggaa cgggagtgaa agatgatgac tttgttcgtg
     8641 agttagtgtc aactagcacc catgatcatc tgctcttctt cacaaacaag ggacgtgtct
     8701 atcgtcttaa aggttatgaa attcctgagt atggtcggac tgccaaaggg ctaccagtag
     8761 tcaatctctt gaaattggat gaagatgaaa gtattcagac ggttatcaat gttgagtctg
     8821 atcgcagtga tgatgcttat ctcttcttta caacccgtca cggtattgtg aagagaacta
     8881 gtgttaagga gtttgccaat attcgtcaaa atggtctcaa agcgctgaat ttaaaggatg
     8941 aagatgagtt aatcaatgtc ttgttgacag aaggagatat ggatattatc attggtacca
     9001 agtttggtta tgcagttcgc tttaatcaat cagccgttcg tggtatgagc cgtatcgcca
     9061 ctggtgtgaa aggtgttaac cttcgtgaag gagacacagt tgttggtgcc agcttgatta
     9121 ctgatcaaga tgaggttctt attatcacag aaaaaggata tggtaagcgt acagtcgcta
     9181 ctgaataccc aacaaaaggt cgtggtggta agggaatgca gacagctaaa attaccgaaa
     9241 aaaatggctt gctggccggt cttatgactg ttcaaggtga tgaggatttg atgattatca
     9301 ctgatacagg tgtcatgatt cgaaccaatc ttgccaatat ttcacaaaca ggacgtgcaa
     9361 ctatgggagt taaagtaatg cgcctggatc aagatgctca gatagtgact ttcacaacgg
     9421 ttgcggtggc agaaaaagaa gaagttggga cagaaaacga aacagaaggt gaagcataat
     9481 gtctcaaaaa aataataaaa agaaaaacaa gcgaaaaaat ctgctgacaa atatcctagc
     9541 aggatttctg atattactgt cactggcttt gatttttaat actcaaattc gaaatatttt
     9601 catagtctgg aataccaata agtatcaagt tagccaggta tcaaaagaaa aattagaaga
     9661 aaatcaggat acagaaggca attttgactt tgattctgtc aaagctatct cttcggaagc
     9721 tgttctaact tctcaatggg atgctcaaaa attaccagtt attgggggaa ttgcaattcc
     9781 tgaattggaa atgaatttgc cgatttttaa aggacttgat aatgttaatc tcttctacgg
     9841 agctggtaca atgaaacgcg agcaagtaat gggagaagga aattatagtc tagctagtca
     9901 ccatatcttt ggtgttgata atgctaataa aatgttattt tctcctttag ataatgctaa
     9961 aaatggcatg aagatttatc taaccgataa aaataaagtt tatacttatg aaatacgtga
    10021 agtcaaacgt gtgacaccgg atcgtgttga tgaagttgat gatagagatg gggtcaatga
    10081 aatcacatta gtaacctgtg aagaccttgc tgctacagaa cgtattattg tcaaaggtga
    10141 tttgaaagaa acaaaagatt attcacaaac atctgatgaa atcctaacag
//
LOCUS       DAVMCN010000062         9724 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVMCN010000062 DAVMCN010000000
VERSION     DAVMCN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.063"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..144
                     /locus_tag="VYP85_001762"
     CDS             <1..144
                     /locus_tag="VYP85_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1882237.1"
                     /translation="IINNSSSSQTNILAQLMDFFTGNGYLEDLSKISEPEKLYAYIAE
                     ATA"
     gene            182..484
                     /locus_tag="VYP85_001763"
     CDS             182..484
                     /locus_tag="VYP85_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1882238.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIILPAKQNMV"
     gene            492..1295
                     /locus_tag="VYP85_001764"
                     /pseudo
     CDS             492..1295
                     /locus_tag="VYP85_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1332..1808
                     /locus_tag="VYP85_001765"
     CDS             1332..1808
                     /locus_tag="VYP85_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1882239.1"
                     /translation="MPYFIGGHPGFNCPLLDDGVYEDYYLESEKEETCSVPRPFPETG
                     MLDFQDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFP
                     NLIIWSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            1965..2390
                     /gene="lacA"
                     /locus_tag="VYP85_001766"
     CDS             1965..2390
                     /gene="lacA"
                     /locus_tag="VYP85_001766"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1882240.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2421..2936
                     /gene="lacB"
                     /locus_tag="VYP85_001767"
     CDS             2421..2936
                     /gene="lacB"
                     /locus_tag="VYP85_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1882241.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHHESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2947..3876
                     /locus_tag="VYP85_001768"
     CDS             2947..3876
                     /locus_tag="VYP85_001768"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1882242.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQDPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            3878..4858
                     /gene="lacD"
                     /locus_tag="VYP85_001769"
     CDS             3878..4858
                     /gene="lacD"
                     /locus_tag="VYP85_001769"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1882243.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5092..5928
                     /locus_tag="VYP85_001770"
     CDS             5092..5928
                     /locus_tag="VYP85_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1882244.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5964..6281
                     /locus_tag="VYP85_001771"
     CDS             5964..6281
                     /locus_tag="VYP85_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1882245.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6281..7972
                     /locus_tag="VYP85_001772"
     CDS             6281..7972
                     /locus_tag="VYP85_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1882246.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARYFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8187..9593
                     /gene="lacG"
                     /locus_tag="VYP85_001773"
     CDS             8187..9593
                     /gene="lacG"
                     /locus_tag="VYP85_001773"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1882247.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHKNPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9636..>9724
                     /locus_tag="VYP85_001774"
     CDS             9636..>9724
                     /locus_tag="VYP85_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 domain-containing protein"
                     /protein_id="HEV1882248.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTS"
BASE COUNT         3076 a         1753 c         2021 g         2874 t
ORIGIN      
        1 atcatcaata attcaagttc aagtcaaaca aatattctgg ctcagttgat ggactttttc
       61 acaggaaatg gttatcttga agacctatca aaaatttctg aaccagaaaa actttatgct
      121 tacattgctg aagcaaccgc ttaatcttgt ctattaaaaa ataaaatcgg aggaaatcca
      181 aatgattaaa attcttgctg cctgcggtgc aggtgttaac tcaagtcacc aaattaaaag
      241 tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt cactgtgatg cagtcatggt
      301 gaaagatgta aacgaagacc ttatgaaagg ttacgatatc tttacaccaa tcgctgcaac
      361 agaccttggt tttgaaccag gtatcccagt tatcgaagct ggtccaatct tattctgtat
      421 cccagcaatg agcgttccag tatttgacaa tattatactt cctgcgaaac aaaatatggt
      481 atagtagttc tatgaatgat gaagcaagta aacaactaac tgatgcacga tttaagcgtc
      541 ttgttggtgt tcagcgtacc acttttgaag agatgttagc tgtattaaaa acagcttatc
      601 aacttaaaca cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac cttcttatgg
      661 ccactcttca atagtgcgag aatatcgaac ttatgaacaa attgcggctg attttggtat
      721 tcacgaaagc aactttatcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg
      781 tgttacggtt tcaagaactc ctctcagctc tgaggacacg gtaatgattg atgcgacgga
      841 agtacaaatc aatcgaccta aaaaaagaat tagcgaatga ttctggtaaa aagaaatgcc
      901 acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatca
      961 ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag ttgcagaaat atcggacaag
     1021 ctggtaaaat cttggctgac agtggttatc aaggactcat gaagatatat cctcaagtac
     1081 aaactccacg taaatccagc aaactcaagt cgctaatagc tgaagataaa gcctataacc
     1141 atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta aaaacgttta
     1201 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     1261 gtgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aataaagaaa
     1321 ctagcaaggt catgccttac tttattggtg gacatccagg atttaattgt cctctacttg
     1381 atgatggagt ctatgaagat tattatctag agtctgagaa agaagagact tgctctgttc
     1441 cacgtccttt cccagaaaca ggtatgttgg atttccaaga tagaagtcca tggctagagg
     1501 gacaaaaaga aatagatctt agttatgatc ttttcagcac agatgcagtg actttggatg
     1561 aattgcaatc tcgaacaatt gcccttcgtt ctcttaaaca tgataaggga ttgaaagtgc
     1621 attttgcaga atttccaaac ctcatcatct ggtcaacttt gaacaaggga cctttcatta
     1681 cctttgaacc atggtctggc ttgtcaacat tccttgaaga aggagatcat ttagaagata
     1741 agaagaatgt ttgtctctta gaagccaatc aggttgaaga attagggttt gagatagaag
     1801 ttttataaaa aagtaaaaaa taaataacaa aaacaaacac aaactattga cttcttcaaa
     1861 caatagtagt atattatgtt tgtgaggact aattgactgt tttttaaaga cagccaatac
     1921 actgctggaa tccagcatag aaaaaataaa aaggagtata caatatgtct attgttatcg
     1981 gtgcagatgc tgcaggtttg agattgaaag aagttgtgaa agacttctta gaaaaagaaa
     2041 acttccacct tgtggatgtt acagctgaag gtcaagactt tgttgatgtg actctcgctg
     2101 ttgctgcaga agtaaacaaa gaagaacaaa accttggtat cgtgattgat gcttatggag
     2161 ctggtccatt tatggttgca actaagatca aaggaatggt tgctgcagaa gtatctgacg
     2221 aacgttcagc ttatatgact cgtggccaca acaactcacg tatgatcact atgggggcac
     2281 aacttgttgg tgatgaattg gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg
     2341 acggtggacg tcatcaaatc cgggttgaca tgttgaacaa aatgggctaa ttagattaca
     2401 gtaagaaagg taagttaaaa atgagaattg caattggatg tgaccacatc gtaactgatg
     2461 aaaaaatggc ggtttcagaa tttttgaaat caaaaggata tgaagtcatt gactttggta
     2521 cctatgacca tacacggact cactacccaa tctttggtaa aaaagtaggg gaagcagtaa
     2581 ctagtggtca agctgatctc ggggtatgta tctgtggtac tggtgttggt atcaacaacg
     2641 ctgtaaataa agttccaggt gttcgttctg ccttggttcg tgatatgaca acagcccttt
     2701 atgctaaaga acaattgaac gccaacgtta tcggttttgg tggtaagatt actggtgaat
     2761 tgcttatgtg tgatatcatc gaagctttca ttcatgctga atacaaacca tctgaagaaa
     2821 acaaaaaatt gattgcgaaa attgaacacc atgaaagtca caatgctcaa caaacagacg
     2881 caaacttctt cactgaattc cttgaaaaat gggatcgcgg agaataccac gactaagagg
     2941 taacctatga ttttaacagt tacaatgaac ccatccattg atatttccta tcccttggat
     3001 gagttgaaga ttgatactgt caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag
     3061 ggactcaatg ttacccgagt actttcagaa tttggtgatt ctgttcttgc tactggttta
     3121 gtgggtggca aacttggtga gtttttggtt gaacatatcg ataatcaagt aaagaaagat
     3181 ttcttctcaa ttcagggaga aactcgtaac tgtatcgcta ttctccacgg agacaaccaa
     3241 acagaagttc ttgaaaaagg tcctgaagta ttggaacagg aaggtcaaga gtttttggaa
     3301 catttcaaaa aactcttgga atcagttgaa gtagtggcca tctcaggtag tctgccagct
     3361 ggccttccag ttgattacta tgcgagcttg gtagaacttg ctaatcaagc tggcaagcct
     3421 gtagtcttgg actgctcagg tgcagcactt caggctgttc ttgaatcacc ccataaacca
     3481 acagtcatca aaccaaataa tgaagaattg tctcagcttc ttggaagaga agtttctgag
     3541 gatttggatg aattaaaaga agtacttcaa gaccctttgt ttgcagggat tgaatggatt
     3601 atcgtttcac ttggtgccaa cggtactttt gccaaacatg gtgacacttt ctacaaggta
     3661 gatattccta gaattcaggt ggtaaatcct gttggatctg gagactctac tgtggcagga
     3721 atttcttcag gacttcttca caaagaatcg gatgcagaat tactcatcaa ggcaaatgtc
     3781 cttggtatgc tcaatgctca agaaaaaatg actggtcatg tcaacatggc caactatcaa
     3841 gttctatatg atcaattaat agtaaaagag gtataaaatg gctttaacag aacaaaaacg
     3901 tgtacgctta gaaaaacttt ctgatgaaaa tggtatcatc tcagctcttg catttgacca
     3961 acgtggtgct ttgaaacgcc tcatggctca acaccaaaca gaagaaccaa ctgtggccca
     4021 aatggaagaa cttaaagtct tggtagcaga tgaattgact aaatacgctt catctatgct
     4081 tcttgaccct gagtatggac ttccagcaac taaagctctt gatgaaaaag ctggtcttct
     4141 ccttgcttat gaaaaaacag gttatgacac aacaagcaca aaacgcttgc cagactgctt
     4201 ggatgtctgg tctgcaaaac gtattaaaga agaaggtgca gatgcagtta aattcttgct
     4261 ttactatgat gtagatagct cagacgaact caatcaagaa aaacaagcct acatcgaacg
     4321 catcggttct gagtgtgtgg ctgaagatat cccattcttc cttgaaatcc ttgcttacga
     4381 tgaaaaaatt gcggatgcag gttctgtaga atacgcgaaa gtaaaaccac acaaagttat
     4441 cggcgctatg aaagtctttt cagacccacg ctttaacatt gatgtcttga aagttgaagt
     4501 tcctgttaac attaaatatg ttgaaggctt cgctgaaggt gaagtagttt atacacgtga
     4561 agaagcagca gccttcttca aagcgcaaga tgaagcaacg aacttgccat acatctactt
     4621 gagtgctggt gtatcagcta aactcttcca agatactctt gtatttgctc atgaatcagg
     4681 tgcaaacttt aacggagttc tttgtggccg tgctacatgg gcaggatcag ttgaagctta
     4741 catcaaagat ggtgaagcag cagctcgcga atggcttcgc acaactggat ttgaaaacat
     4801 tgatgagctc aataaagttc ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga
     4861 aagtcctcct agtttaggaa catgaatcta aaaaaattta aaaaaagttg tatgtaaagg
     4921 tttacaaaat aacttacttg tgctatactt aaatcacaag ttaatacaag gtgagtgtta
     4981 ctaagtaata ttaggcatga tcacaggtga attagaaatc agctgatttt ctagttcatt
     5041 tgtggtcatt ttttgtactt atataccttt aagatataaa aggaggttga catgtatcga
     5101 attctaaatc caatgaatca caatgtctcg cttgtcagaa atgataaggg agaagaggtg
     5161 attgtaattg gtaagggaat tgcattcgga aagaagaagg gggatttgat tgctgaaaat
     5221 caggttgaga aaatctttcg gatgaagacc gaagagtcca gagaaaactt tatggctctt
     5281 ctcaaagatg ttccgcttga ttttatcaca gtgacctatg aaatcattga taagctatca
     5341 aagaaatatc attatccgat tcaagagtat ctctatgtaa ccttgacaga tcatatttac
     5401 tgttcttatc aagctctaac tcaaggaagg tacaaggata gtaatctgcc agatatttcc
     5461 gctaagtatc ctgtcgcttt tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag
     5521 ctagcagatc attttcctga ggacgaaatt attcggattg cttatcattt cattaatgct
     5581 gaaggtgaaa atgaagtgga acttgtggag tcgattgata agaggaaaga aattctcagg
     5641 aatgttgaag aagttttaac ggactatgca attcaacgaa ctaaaaagaa taaccatttc
     5701 tatgatcgct ttatgatcca tttgaattat ttcttggatt atttagacag atctagagat
     5761 gataaccaat cacttctgga tatggaagat catattaaac aatcctatcc aaaagccttc
     5821 gagattggtt ccaagatcta tgatgtgatt acgcaacata cgggtcttga tttgtataaa
     5881 agtgaacgag tttatctagt tctacatatc caacgtttat tgtcataaaa atttatttaa
     5941 aactatataa ggagaattct atcatgaata gagaagaagt aacattgtta ggttttgaaa
     6001 tcgtagccta tgctggcgat gctcgttcaa aactattgga agccttgaag gctgctgaag
     6061 ctggtgattt tgaaaaagcg gacgctctgg tagaggaagc tggtagctgt attgcagagg
     6121 ctcaccacgc gcaaacaagt ctattgacta aggaagcttc tggtgaggac ttagcgtata
     6181 gtgtgaccat gatgcatggc caagaccact tgatgacaac tatcttgtta aaggatttga
     6241 tgcaccattt gatcgaactc tataagagag gagttaaata atgaacaaac taattgcatt
     6301 tatcgagaaa ggaaagcctt tctttgagaa actatctcgt aatatctatc ttcgtgctat
     6361 tcgtgatggt ttcattgcag gtatgcctgt tattctcttc tcaagtatct ttatcttgat
     6421 tgcctttgta ccaaactcat ggggctttaa atggtctgat gaagttgtag cctttctgat
     6481 gaaaccttat agctattcta tgggtattct ggctctcttg gtagctggta caacagctaa
     6541 gtcattgacc gactcagtaa accgtagcat ggagaaaacc aatcaaatca actatatgtc
     6601 aacgctgtta gcagcgattg ttggtttgtt gatgttggca gctgatccta tcgaaagtgg
     6661 tctagctact ggattcttgg ggacaaaagg tttgctttca gccttccttg ctgcctttgt
     6721 tactgtagcc atctataagg tttgtgttaa gaacaacgtc actattcgta tgcctgacga
     6781 agttccacca aatatctcac aagtctttaa agatgtgatt ccattcactc tatctgttgt
     6841 ttctctttat gctcttgact tattagcacg ttattttgtt ggttctagtg tggcagaatc
     6901 aatcggtaaa ttcttcgcac cactcttctc agcagcagac ggataccttg gtattaccat
     6961 tatctttggt gcctttgcct tcttctggtt tgttgggatt catggtccat ctatcgttga
     7021 accagctatc gcagctatta cctatgccaa tgccgaagtt aacttgaacc ttctccaaca
     7081 agggatgcat gcagacaaga ttcttacttc tggtacacaa atgtttatcg ttaccatggg
     7141 tggtacaggt gcgacattgg tcgttccatt tatgttcatg tggttgacaa aatcgaaacg
     7201 taaccgtgca atcggacgtg cttcagtagt tcctaccttc ttcggtgtaa atgaaccaat
     7261 cttgtttggt gcacctcttg ttttgaatcc aatcttcttc attccattta tctttgctcc
     7321 aattgcaaac gtatggattt tcaaattctt tattgaaact cttggaatga actcattcac
     7381 tgctaatcta ccatggacaa ctccagctcc actaggtcta gttcttggaa ctaacttcca
     7441 agtgctatca ttcattcttg ctgcccttct aattgtggtt gacgtagtta tttattaccc
     7501 attccttaaa gtctatgatg aacaaattct tgaagaagaa cgttcaggta agtctaatga
     7561 tgaattgaaa gaaaaagttg ctgcaaactt caacactgca aaagcggatg ctattcttga
     7621 aaaagcgggt gtcgatgcag cacaaaatac catcactgaa gaaacaaatg tcctcgttct
     7681 ctgtgctggt ggaggtacaa gtggactcct tgcaaatgct ttgaataagg cagcagcaga
     7741 atacaatgtc cctgtgaaag cagcagcagg cggctatggt gctcaccgtg aaatgttacc
     7801 agagtttaat ctagttatcc ttgcccctca agttgcttca aactttgaag atatgaaggc
     7861 agaaacagat aagctcggta ttaaacttgc taagacagaa ggcgctcaat acatcaaatt
     7921 aactcgtgat ggaaaaggtg ccctagcatt cgtacaagag caattcgatt aaggctagga
     7981 actgtgaaac agtctcccat cgttacggaa atcgctatgg cgaatttcct aatcgcctta
     8041 ttaattcgtc ggtaaaaaga tatcgttttt acctcctcat gtcacaattc agtgacttgg
     8101 tacaagaagt gagatggaga agcatggctc actgactcct ctcctctcac ttttacttta
     8161 tttaaatcaa gaaataggtg aaaaaaatga caaaaacact tccaaaagac tttattttcg
     8221 gtggcgcaac agctgcttat caagcagaag gtgctacaca tactgatgga aaaggaccag
     8281 ttgcttggga taaatatctt gaggataact actggtacac tgccgaacca gctagtgatt
     8341 tttacaatcg atatccagtt gacctcaagc tagcagaaga gtatggtgtc aatggtattc
     8401 gaatttctat tgcttggtca cgtattttcc cgactggtta cggccaagta aatgctaaag
     8461 gtgttgagtt ttatcataat ttatttgcag agtgtcacaa acgtcatgtt gagccttttg
     8521 taactcttca tcactttgac acgccagaag ctctccactc aaatggagac ttcttaaacc
     8581 gtgaaaatat cgaacatttt gtagactacg ctgctttctg ttttgaagaa tttccagaag
     8641 taaactattg gacaaccttt aatgaaattg gaccaatcgg tgatggtcaa tatttggttg
     8701 ggaaattccc tccaggtatc cagtacgacc ttgccaaagt ctttcaatca caccacaata
     8761 tgatggtgtc tcatgcacgc gcggtaaaat tgtacaaaga gaaaggctat aaaggggaaa
     8821 ttggtgttgt tcacgccctg cctactaaat atcctctaga tcataaaaat ccagcagatg
     8881 ttcgtgcagc tgagttggaa gatattattc acaacaaatt tattttggat gcaacctatc
     8941 tgggtcacta ctctgaaaag actctggcag gggtagaggc tatcttggct gccaatggtg
     9001 gtagcttgga tcttcgtgaa gaagatttta cagcattaga agctgcaaaa gacttgaatg
     9061 atttcctagg aatcaactac tatatgagtg actggatgga agcctttgat ggagaaactg
     9121 aaattatcca taatggtaaa ggtgaaaaag gaagctctaa ataccaaatc aaaggtattg
     9181 gtcgtcgtgt agctcctgac tatgtaccac gcacggattg ggattggatt atctaccctc
     9241 aaggtttgta tgaccaaatc atgcgcgtga agaaagatta tcctaactat aagaaaatct
     9301 acatcactga aaatggtctt ggatataaag atgagttcgt tgataacact gtttacgatg
     9361 atggacgtat tgattacgtg aagcaacact tggaggtttt atctgatgcg attgcagatg
     9421 gagctaatgt aaaaggttac ttcatttggt cattaatgga tgtcttctca tggtcaaacg
     9481 gttatgagaa acgttatggt ctcttctacg tagattttga aactcaagaa cgttatccta
     9541 agaaatcagc tcactggtac aagaaagtag cggaaactca gattatagac tagtagaatt
     9601 agtcattaga tatagaattt tagtgagtcc aaaagatgtt caaagatttt atccaatcta
     9661 tttatgaaaa agtttatatt ataaatttcg aaaaatgctc tcaaataccg tgtttgacga
     9721 gtga
//
LOCUS       DAVMCN010000063         9715 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVMCN010000063 DAVMCN010000000
VERSION     DAVMCN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.064"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            223..318
                     /locus_tag="VYP85_001775"
                     /pseudo
     CDS             223..318
                     /locus_tag="VYP85_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(571..1191)
                     /locus_tag="VYP85_001776"
     CDS             complement(571..1191)
                     /locus_tag="VYP85_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1882249.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(1191..1673)
                     /locus_tag="VYP85_001777"
     CDS             complement(1191..1673)
                     /locus_tag="VYP85_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1882250.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1673..2515)
                     /locus_tag="VYP85_001778"
     CDS             complement(1673..2515)
                     /locus_tag="VYP85_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1882251.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSH
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2610..3410)
                     /locus_tag="VYP85_001779"
     CDS             complement(2610..3410)
                     /locus_tag="VYP85_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1882252.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3554..4933
                     /gene="glmU"
                     /locus_tag="VYP85_001780"
     CDS             3554..4933
                     /gene="glmU"
                     /locus_tag="VYP85_001780"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1882253.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4943..5488
                     /locus_tag="VYP85_001781"
     CDS             4943..5488
                     /locus_tag="VYP85_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1882254.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5500..5814
                     /locus_tag="VYP85_001782"
     CDS             5500..5814
                     /locus_tag="VYP85_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1882255.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5831..6523
                     /locus_tag="VYP85_001783"
     CDS             5831..6523
                     /locus_tag="VYP85_001783"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1882256.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6600..7091
                     /gene="rocS"
                     /locus_tag="VYP85_001784"
     CDS             6600..7091
                     /gene="rocS"
                     /locus_tag="VYP85_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1882257.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7189..7779
                     /locus_tag="VYP85_001785"
     CDS             7189..7779
                     /locus_tag="VYP85_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1882258.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7788..9551
                     /locus_tag="VYP85_001786"
     CDS             7788..9551
                     /locus_tag="VYP85_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1882259.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3003 a         1680 c         2071 g         2961 t
ORIGIN      
        1 ttaacacctg ataatatgcg ttttttgatt ttaaagactt tttgaccagt ctcatttttt
       61 taacttgata ctcagtgcaa agcaaagatt aaactaggaa gctagctgta ggctgctcaa
      121 agaacagctt tgaggttgta gataaaactt gtgaggtcac caacatatat aatgtgaagc
      181 tgacgtggtt tgaatagatt ttagaagagt atgagtctgg aagttttaat ggataatgca
      241 agattccata gaatgggtaa gctagagttc ttatgtgaag agtttgggca taaactttta
      301 ccttttcctc cctactcatc ttagtataga aaagtgaatc tgaaatagta cataactgct
      361 tctaaaacat tcttataaat tgatttaaat tctcaaatca tattattcag ttcttatttc
      421 attttgttct acaatcctgt tgagaagaca cgtgttcata tcaaaaaggt attggcaagt
      481 tgcaatacct ttttacgagg ctctgttgtc ttatttttgt ttcaactgac tatatctcct
      541 atggttctag ttcagaaggc taggctataa ttatgattga taagaagtat cattccaagt
      601 attgggagtg aatgtttcaa aatcatgggt ttctataatg gtcaggctgg catttgctag
      661 accgccatct ttacgaagaa gtggttcttt atagcctagg agagtacgaa gactggcagt
      721 aagattggcg ccgtgtccga caattagaat acgttcagct ggactatctt ttaatgattt
      781 gataaattgg atggtccgtt gagttgtact atagagggat tcggctccga acattcgagt
      841 gtcaaattga gcaagatttg aacgaaaagc ctggatttgt tgcgggtaaa tagcttccaa
      901 ggttgcaatt ttcaaacctt ctaacttccc aagttgccat tcacggagat taggaacgat
      961 ttctaaagaa cagggggtat agagttgact ttggataatc tcagcagatt tgaccgctcg
     1021 aggtaaatca cttgaataaa tctgatcaaa aggaatttcc ttgagatact gaccaagtcg
     1081 ttttagggtt tcaatggatt caggaagaag aggagaatca ccactagcac cttgaaaacg
     1141 accttcttgg ttccagaggg tacgaccgtg gcggacaaag tagagtttca ttacttgatg
     1201 tcctccaaaa tatctacaaa gtctgccttt acaaagctag ccaagtcttg tggcgcgacg
     1261 ataatgctgt gtccgacttc gcctgcagag acaatcattt gatccaaatc tagagcaatt
     1321 ttatcgataa aaatgggata attgtgtttc tgacgaattc cgacaggatt attggctcca
     1381 tgaatgtaac cagttgtttt ttctaagtcc ttttgtggaa tcatgctcac ttttttattg
     1441 ccagaaattt tagctagttt cttttcagac aagtgctgag tgatagggac aattccgata
     1501 atcggtccgg tcttgtctcc caaaagcgcc aaggttttga aaatctgatc tcgttcataa
     1561 ccttgaggaa gctctccttc tagggcattg atttgaatcc cctgatgagg gatagctgct
     1621 ttagatagga tttgttccac caatgttttt ttgattttaa ctttttttgc cattatttat
     1681 atttatcctc caattgactc atccaaatac caagccagat tcccagcgca aagaagaagg
     1741 cgatgatgac ataaccgaca agtgaaagtc ctgtgtattg gatactttca gcgtttcctg
     1801 catttggaat taagatcaaa agggtacttg ataggacgat accgatgatg aaatgataga
     1861 cgtgtgagtg gtagttgttt aaggcataat ccatcaattt tgaaaaaacg atgagagttg
     1921 cacctgcacc aattccaatc ggaaagaagg ttcccaagag atcaaaagtt ttaaaaccag
     1981 tcaacatagg agcatagagt cccaaaatca aaagtaagtt cgatgggctg aggccaggaa
     2041 ccaagacgcc aagggccaat agtgcgcctg ctaggacgaa gttaagaaag ctggcgctta
     2101 aggttccaac gacaaaattt aaggcataga gtcctaatcc agaaatgata aaggttgtcc
     2161 ataaccaagc taaatcaatc ttgtctcggt cagattctcg agttgattct ttgaggaggc
     2221 taggaactgt accgataata gctcccgcaa agctccataa tacaaaaacc tgataatttt
     2281 caagcaggta ttcaatcggg taggaaaata agccgattcc cagaagcata ccgatggcaa
     2341 ctggaataaa gtacaaaaca ttttctttaa agtctttaaa gggatgggcc agaaagccaa
     2401 tcattcgttc atagattcct aagattgctg ctagaacccc tccggaaatt cccggtagga
     2461 taaatccaag agcaattaca atccctttaa taacgcgtgc taaccatgag agcatatatt
     2521 tcctccaact atttctattt caaaaaatcc ttactatatt gtatcacaat cagacacaaa
     2581 aagaaaaagc aaatgataaa caaatgcttt taaggtttta aaaaaagttt tcgaaaggtt
     2641 tcttctttat tttttaaggg agagataacg ttgatatcta aatcgtggtc aaagccagca
     2701 atttttcctt tagatgtgta ttggtgaata tcataatcta aatcagtttt aggactgctc
     2761 tccaaaaatc ctgagtctga gccgtaggac ggaatccaaa cagaggtaaa cttgcctgta
     2821 tcaatactgt gttcttccat gaagtagaca ccaacgtaga tgccgatgtt tttagcacct
     2881 agtgatgcta gttttgctcg aaagttttcg acaccttcgt tcatattaga catggttttg
     2941 tcttccacgt caagccaata gtaactaggg ctgtaaggag aggcagcatt gtagaaaact
     3001 tcggcagcct tttccatttc ttggacactt tttccagcta cataagcgta gacagcaact
     3061 gggacattcc gcttttgaag ttcagtgata tgactcttat aggccttgtc tattccattg
     3121 ataaatgaag catcattttc ttttgttgtt tgagcaccac tgtgaacacg aacaatagca
     3181 cctgaaatat tttgtgagag ggcatcgtag ttgatttcct caggacgctg ccagccagag
     3241 aggtcaataa tcggtttgtc taagtgtttc aaagcctgtg cttcaatctg tgctatattg
     3301 gattttgttt taaacgattg gctgtcatta agtgggcgat tgatgattaa aatgaacatc
     3361 ataatcccaa aaaaactaaa taaaataagt ggatgaattt gttttctcat atcttataat
     3421 tctaccctaa aaatcaaaaa aaatcaaaaa aatgggttaa ggaagagact ttagagcatt
     3481 ttttcattca agagtgcgga atgatttgaa atatggtata ataaaaggga atttctacag
     3541 aaaagagaag attatgtcaa attttgccat tattttagca gcgggtaaag ggactcgcat
     3601 gaaatctgat ttgccaaaag ttttgcacaa ggttgcgggt atttctatgt tggaacatgt
     3661 tttccgtagt gtgggagcta tccaacctga aaagacagta acagttgtag gacacaaggc
     3721 agaattggtt gaggaggtct tggctgaaca gacagaattt gtgactcaat ctgaacagtt
     3781 gggaactggt catgcagtta tgatgacaga gcctatctta gaaggtttgt caggacacac
     3841 cttggtcatt gcaggagata ctcctttaat cactggtgaa agcttgaaaa acttgattga
     3901 tttccatatc aatcataaaa atgtggccac tatcttgact gctgaaacgg ataatccttt
     3961 tggctatgga cgaattgttc gtaatgacaa tgctgaggtt cttcgtattg ttgagcagaa
     4021 ggatgctaca gattttgaaa agcaaatcaa ggaaatcaac actggaacat acgtctttga
     4081 caacgagcgt ttgtttgagg ctttgaaaaa tatcaatacc aataacgctc aaggcgaata
     4141 ctatattaca gacgtcattg gtattttccg tgaaactggt gaaaaagttg gcgcttatac
     4201 tttgaaagat tttgatgaaa gtcttggggt aaatgaccgt gtggcgcttg cgacagctga
     4261 gtcagttatg cgtcgtcgca tcaatcataa acacatggtc aacggtgtta gctttgtcaa
     4321 tccagaagca acttatatcg atattgatgt tgagattgct ccggaagttc aaatcgaagc
     4381 caatgttatc ttgaaagggc aaacgaaaat tggtgctgag actgttttga caaacggtac
     4441 ttatgtagtg gacagcacta tcggagcagg agcggtcatt accaattcta tgattgagga
     4501 aagtagtgtt gcagacggtg tgacagtcgg tccttatgct cacattcgtc caaattcaag
     4561 tctgggtgcc caagttcata ttggtaactt tgttgaggtg aaaggatctt caatcggtga
     4621 gaataccaag gctggtcatt tgacttatat cggaaactgt gaagtgggaa gcaacgttaa
     4681 tttcggtgct ggaactatta cagtcaacta tgacggcaaa aacaaataca agacagtcat
     4741 tggaaacaat gtctttgttg gttcaaattc aaccattatt gcaccagtag aacttggtga
     4801 caattccctc gttggtgctg gttcaactat tactaaagac gtgccagcag atgctattgc
     4861 tattggtcgc ggtcgtcaga tcaataaaga cgaatatgca acacgtcttc ctcatcatcc
     4921 taagaaccag taggagccta tcatggagtt tgaagaaaaa acgcttagca gaaaagaaat
     4981 ctatcaagga ccaatattta aactggtcca agatcaggtt gaattaccag aaggcaaggg
     5041 aactgcccaa cgggatttga tttttcacaa tggggctgtc tgtgttttag cagtaacgga
     5101 tgaacaaaaa cttatcttgg tcaagcagta ccgcaaagct atcgaggcag tctcttacga
     5161 aattccagcc ggaaaattgg aggtaggaga aaacacagcc cctgtcgcag ctgcccttcg
     5221 tgaattagag gaagaaacag cctatacagg gaaattagaa ctcttgtacg atttttattc
     5281 agctattggc ttttgtaatg agaagttaaa actatattta gcaagcgatt tgacaaaagt
     5341 ggaaaatccg cgtccgcagg atgaggatga aaccttggaa gtccttgaag tgagcttaga
     5401 agaagcgaaa gaattaatcc aatcaggtca tatctgtgat gccaagacaa ttatggctgt
     5461 tcagtattgg gagttgcaga aaaaatagag gaggtcagta tgggtaaatc tttattaacg
     5521 gatgaaatga ttgaaagagc taatagaggc gaaaaaattt caggtcctcc tttgctagat
     5581 gataatgagg aaactaagat tttaccaacc tcttcttccc gttttggtta tgccaatcct
     5641 aaggatcatg gttttagcca ggaaaccttg aagattcagg tcgaaccatc tattcataaa
     5701 agccgtcgta ttgaaaatac caagagaaat gtcttcaatt ctaagttgaa taaaatctta
     5761 ttcgcggtca tctttctctt gattttgctt gttttagcaa tgaaactttt gtaatagaaa
     5821 aggaattgaa atgaaaatag gaattattgc tgctatgcca gaagaactgg cttatctggt
     5881 ccagcattta gacaatgccc aggagcaagt tgttttgggg aatacctatc atacaggaac
     5941 cattgcttct catgaagtcg ttcttgtaga aagtggaatt ggtaaggtca tgtctgctat
     6001 gagtgtggcg attttggctg atcatttcca ggtggatgcc cttattaata cgggttcagc
     6061 tggggcagta gcagaaggta tcgctgttgg ggatgtcgtg attgctgaca aattagccta
     6121 tcatgacgtg gatgtcacag cttttggcta tgcttatgga caaatggcgc aacaaccgct
     6181 ttatttcgaa tcagacaaaa cctttgttgc tcaaatccaa gagagtttat ctcaattgga
     6241 ccaaaactgg catcttggtt tgattgctac aggagatagt tttgttgcag gaaatgacaa
     6301 gatagaagcg attaagtccc atttcccaga agttttagcc gtggagatgg agggggcagc
     6361 tattgctcaa gcagcgcatg ccctcaatct cccagtctta gtcatcagag ctatgagtga
     6421 caatgccaac catgaagcaa acatcttttt tgatgagttt attatcgaag ctggacgtcg
     6481 ctctgcccaa gtcttgttga cctttttgaa ggctttagat taagtggaaa tttgacagtt
     6541 tttctagctt atgataagat ttaagtaaag aaaagctaga aaacgtttca gaggatatta
     6601 tgagtattga aatgaccgtc agtgagattg cagaggtctt aggattatct cgccaagcaa
     6661 tcaataaccg tgtcaaagaa ttaccagaag aagacacaga taaaaatgac aaaggggtaa
     6721 cagttgttac cagaagtggc ttgattaagc tagaagaaat ctataaaaaa acgatttttg
     6781 aagatgaacc tgtcagtgaa gatgtcaaac aacgtgaact gatggagatt ctagtggatg
     6841 agaagaatgc agaaattctt cgtctttatg aacaattaaa agccaaggat cgtcagttat
     6901 cagaaaaaga cgagcagatg cgtatcaaag accgtcagat tgctgagaaa gacaaacaat
     6961 tagatcagca acaacaattg acccttcaag ccatgaagga tcaagaaaat cttaagctag
     7021 agctggacca agcaaaagaa gaagtccaat ccactaaaaa aggctttttt gctcgtttat
     7081 ttggaggata atcaaggagc tgtttaggtt aaatgctaac ctgatggctt cttttgtttg
     7141 tgaatagtat agttgattag aacagagaca gtagaggaga ggtacagaat ggaacgatta
     7201 gaagattaca ttgcttttga tttagaattt aatcagcatg aaggacaaac acacttgatt
     7261 caagtatcgg cagtgcgttt tagagatggt cgggaaatcg atgcctatga ttcctatgtt
     7321 cataccagcg tccctctaaa aagctttatc aatggtttga ccgggattac agctgagacc
     7381 ttaaaagatg ctcctccagt tgagaaagtc ttagaagaat tccaagagtt tgtgggttct
     7441 ttgctgatga taggctacaa tgctgctaaa agtgatttac ctattttagc agagcatggt
     7501 ttagactata gccaacagta caaggtggat ttgtatgatg aagcttttga acgtcggagt
     7561 tcagatttac atggtattgc caatctcaaa ttgcaaactg ttgcctcatt tcttggattt
     7621 caaggtcagt ctcataatag tttagaggat gctcggatga cggcgcgtgt ttacgaatcc
     7681 ttcttagagt cggatcaagc tagggaattg ttagagacag aaagtagctt atcaaacaat
     7741 ccttttggtg gcttggactt gtctcaatta tttgactagg agtgcctatg aaacctgaaa
     7801 aacctaaaaa attgggtctt aaacagattt acctcaatct tgataaaatc ctctttctat
     7861 ttttcttgat ttttatgata gtggagtatt tgtgggtacc attcaattca tggttggcta
     7921 gcttcttatt agatcagaca ggttatcttt ttatttccta taacaatgtc ttagccatcc
     7981 ttactcattc tccattgatt agtctagctt ttttagcctt gattgtaatt aactttctgg
     8041 ttgcttattt tcaaatagga ctcctcttta ttggtgctcg tcatctcctc tataatgaaa
     8101 agcgaaggct aattgagtat atccgcaagg ttttccatga aagttttgaa tttatgaaaa
     8161 agctaactgg cgctaaagcc ttgtttatct ttttctatat agctatgctg tttcctttta
     8221 tacggaaaat gctgaagatt tattatctta ataaaatcgt cattccagag tttatccaag
     8281 cttatttaga agataaatat tggatgtggt ggctgagcat cctacttcta tctcttatct
     8341 ttctctatgt ctctgtcaga ttgatgtttg cccttccgaa gattgtatat gatcagctga
     8401 ctgttcgaga agcagtgatg tttagcttgg agaaaaccaa gaagagagtt actttttatg
     8461 cttggaattt attttacatc ttgctcaaag cacatttatt attttatctt cctttgattc
     8521 ctttattatt ggctcaaact ttggtagatg atatcactca gagagagtct ctgattcttg
     8581 gtattttgaa ttttgttgtg attaaaaatc tctattatat ggctctgact tattttttgg
     8641 ttaaatttgt ttcatttttg acaggaaagg agctggatat gcttcctagg agagaaaaag
     8701 atcacatcgt gcgatggggt gtcatgactt gtgccagtct tttctttgcc ttagaaggtt
     8761 atatttatct ggaggctccc atggttcatc tacctcaact tatttctcac cgaggggttt
     8821 ccaatgcaaa tgggattcaa aatacagtag agtccttgga aactacagca caactcaaac
     8881 cagacttggt ggagacggac gtgcaggaaa caaaagatgg gcagtttgtc atgatgcatg
     8941 atgctaactt gaaaaatcta gcaggtatca ataaaagtcc tcaagactta aacttggagg
     9001 agcttaaagg gattgatatt tttgaaaatg gctaccagac taaaatttca agctttgaag
     9061 attatctcag tcgagccaac gaacttggtc aaaaattact aattgaaatt aaaaccagta
     9121 aaaaagatag tccagacatg atggaccgct ttttagcccg ttatgctgca aagctcaaga
     9181 tttatggaca tcaaatccag tctttagact accatgttgt cgaaaaagta agacagtatg
     9241 atgccgaact gccagtttat ttcatcatgc cctacaattc tgtctttcct aaaacaagag
     9301 cgacaggata tactatggag tactcaacct tggatgaata ttttgtaagc aaactatgga
     9361 caacggatca gaaactttat gtctggactg tcaatgattc agaagctatc agcaaatctc
     9421 ttcacttagg agtagatgga gtgattacag atgatttgga aaaagttcag cgggaaatag
     9481 aagtagccca agaagatcca gaatatacgg atttgctctt gaaaaaagca ttggaattct
     9541 ttgaatttta gtaataaaaa agaggaacgg ttgttcctcc catgataggt aagtattctt
     9601 gtgaatgctt gcttttttgt ggttgcaatc cgtttacgag aattgtttgt attgttcttg
     9661 tttcaattta ctttatagtg ctttgaagtt ggaatgctac actataactt ctaaa
//
LOCUS       DAVMCN010000064         9625 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVMCN010000064 DAVMCN010000000
VERSION     DAVMCN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.065"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VYP85_001787"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VYP85_001787"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1882260.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VYP85_001788"
     CDS             1085..2809
                     /locus_tag="VYP85_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882261.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            2811..4562
                     /locus_tag="VYP85_001789"
     CDS             2811..4562
                     /locus_tag="VYP85_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882262.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLFMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            4954..6213
                     /locus_tag="VYP85_001790"
     CDS             4954..6213
                     /locus_tag="VYP85_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1882263.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6289..6424
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6463..6963
                     /locus_tag="VYP85_001791"
     CDS             6463..6963
                     /locus_tag="VYP85_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1882264.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            7039..7407
                     /gene="rplL"
                     /locus_tag="VYP85_001792"
     CDS             7039..7407
                     /gene="rplL"
                     /locus_tag="VYP85_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1882265.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7608..7781
                     /locus_tag="VYP85_001793"
     CDS             7608..7781
                     /locus_tag="VYP85_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882266.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            7778..8026
                     /locus_tag="VYP85_001794"
                     /pseudo
     CDS             7778..8026
                     /locus_tag="VYP85_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            8016..8363
                     /locus_tag="VYP85_001795"
                     /pseudo
     CDS             8016..8363
                     /locus_tag="VYP85_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8356..8736
                     /locus_tag="VYP85_001796"
     CDS             8356..8736
                     /locus_tag="VYP85_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1882267.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIGLPFVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            8749..8982
                     /locus_tag="VYP85_001797"
     CDS             8749..8982
                     /locus_tag="VYP85_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1882268.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            8985..9572
                     /locus_tag="VYP85_001798"
     CDS             8985..9572
                     /locus_tag="VYP85_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1882269.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT         2854 a         1820 c         2063 g         2888 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gcccaaggac agcagagacc gtctgacaac ttctagtttg gtcactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcttg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tttctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttctggt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tgctcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgttg atcaattccc tcaaccagtc
     1981 ctatatctca gtcaagcgaa tcgaggaagt ctttgttgag gctccagagg atatccattc
     2041 agagttagaa caaaagcaag ctaccagaga taaggtttta caagtccaag aattgacctt
     2101 tacctatcct gatgcggccc agccttctct gagatacatt tcctttgata tgactcaagg
     2161 acaaattcta ggtatcatcg ggggaactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taaaggaacc attcgttcca acttgactct aggtttcaat caagaagtat ctgaccagga
     2401 actctggcag gccttggaga ttgcgcaagc taaggatttt gtcagtgaaa aggaaggact
     2461 cttggatgct ctagttgagg caggggggcg aaatttctca ggtggacaaa aacaaagatt
     2521 gtctatcgcc cgagcagtct tgcgccaagc tccgtttctc atcctagatg atgcaacctc
     2581 ggcactggat accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 cacgagctta attttgatct ctcaacgaac ctcaacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 ccaagtctat tgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag ccgtagattt agcaagccat cctttcctcc
     2881 ttttcctagc ctttctagga actattgctc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgggagcga atcatccata
     3121 agctccatcg tttaccgatt gcctttgtag ataggcaagg tagtggagag atggttagtc
     3181 gtgtaaccac ggacatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggtcagta ttctagccat gctccaaatt catctcttca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agaaatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagtcag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcagcctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggagtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga cgaccagtga ccaagttaag ggagctattt
     3841 cctttaaaca tgtctctttt ggctaccatc ctgaaaaaat tttgattaag gacttgtcta
     3901 tcgatattcc agctggtagt aaggtagcca tcgttggtcc gacaggtgct ggaaaatcaa
     3961 ctcttatcaa tctccttatg cgtttttatc ccattagctc gggagatatc ttgctggatg
     4021 ggcaatccat ttatgattat acacgagtat cattgagaca gcagtttggt atggtgcttc
     4081 aagaaacctg gctcacacaa gggaccattc atgataatat tgcctttggc aatcctgaag
     4141 ccagtcgaga gcaagtaatt gctgctgcca aagcagctaa tgcagacttt ttcatccaac
     4201 agttgccaca gggatacgat accaagttgg aaaatgctgg agaatctctc tctgtcggcc
     4261 aagctcagct cttgaccata gcccgagtct ttctggctat tccaaagatt cttatcttag
     4321 acgaggcaac ttcttccatt gatacacgga cagaagtgct ggtacaggat gcctttgcaa
     4381 aactcatgaa gggccgcaca agcttcatca ttgctcaccg tttgtcaacc attcaggatg
     4441 cggatttaat tcttgtctta gtagatggtg atattgttga atatggtaac catcaagaac
     4501 tcatggatag aaagggtaag tattaccaaa tgcaaaaagc tgcggctttt agttctgaat
     4561 aagccattct cttttgaaag tttatggacg aaaaaagttg ccttcgagtg acttttttgt
     4621 tacaatagct agaaaaattg ttcactgtaa tactcaatga aaatcaaaga gcaaactagg
     4681 aagctagccg taggttgctc aaagcacagc tttgaggttg tagataagac tgacgaagtc
     4741 agttcaaaac actgttttga ggttgcagat agaactgacg aagtcagctc aaaacactgt
     4801 tttgaggttg cagatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat
     4861 agaactgacg aagtcagtaa ccacacctac ggcaaagtga atctgaagtg gtttgaagag
     4921 agtacaactt gtcttttaga aaaggagcct ataatgaaag tctttcagca tgtaaatatc
     4981 gtgacttgtg atcaagattt ccatgtttat cttgatggaa tcttagcagt caaggattct
     5041 caaatcgtct atgtcggtca agataagcca gcgtttttag agcaagctga gcagattata
     5101 gactatcagg gagcttggat tatgcctggt ttggtcaatt gtcacaccca ttctgcaatg
     5161 acaggtctga gagggatccg agatgacagc aatctccatg aatggctcaa tgactatatt
     5221 tggccagcag aatctgagtt tactcccgac atgactacca atgcggtcaa agaagccctg
     5281 acagagatgc tccagtcagg aacaacaacc tttaacgata tgtataatcc caatggtgtg
     5341 gatatccagc aaatttatca ggtggtgaaa acttccaaga tgcgttgtta tttttctccg
     5401 actctctttt cttcagagac agaaacaact gctgagacta taagtagaac tcgatccatc
     5461 atagacgaaa tcttaaaata taaaaatcca aatttcaagg ttatggtagc acctcattct
     5521 ccgtatagct gcagtagaga cttgctggaa gcgagtttgg aaatggcaaa agagctaaat
     5581 attccgctcc atgtccatgt ggcggagacc aaggaggagt caggaattat cctcaaacga
     5641 tacggcaaac gcccccttgc ttttcttgaa gaactgggtt atttagatca tccgtccgta
     5701 tttgctcacg gggtcgaatt aaacgagaga gaaattgaac gcttggcatc ttctcaagtg
     5761 gctatcgccc acaatcctat cagtaacctc aaactggcat caggaattgc tccaattatc
     5821 cagctccaaa aagcgggagt agcagtcgga attgcgactg actcggttgc ttccaataac
     5881 aatctagata tgtttgagga aggaaggact gcagctcttc ttcagaagat gaaaagtggg
     5941 gatgccagcc agtttccaat cgaaacagct ctcaaggtac tgacaatcga aggggctaag
     6001 gtccttggaa tggaaaatca gataggaagt ctggaagtcg gcaagcaagc agattttctg
     6061 gtcattcaac cacaagggaa aattcatctc caacctcagg aaaatatgct gtctcacctg
     6121 gtttatgcag ttaaatctag tgatgtagat gatgtttata tcgccggaga acaggttgtt
     6181 aagcaaggtc aagtcctgac agtagaactt taaaagaaaa attacgaaaa attttaaaaa
     6241 aagtttgcaa aaatcttgca ttcttttttt gactatgcta tacttatata cggtttaaaa
     6301 aaactgccta agacagtagg ggagctcgac tcataaatat cctaccgagg acaaaacgta
     6361 tcatgtaaaa agaagcgtat tgtactttcg tgtctaggtt tgggcgcgtt tttctttttg
     6421 aaaaattccc caagcaaaat aattacggag gtgaacacac taatgagtga agcaattatt
     6481 gctaaaaaag cggaactagt tgacgtagta gctgaaaaaa tgaaagctgc tgcatctatc
     6541 gtcgttgtag acgctcgtgg tttgacagtt gagcaagata cagttcttcg tcgtgagctt
     6601 cgtggaagcg aagttgagta taaagttatt aaaaactcaa tcttgcgtcg tgcagctgaa
     6661 aaagctggtc ttgaagatct tgcatctgta tttgttggac catctgcagt agcattttct
     6721 aatgaagatg ttatcgcacc agcgaaaatc ttgaacgact tttctaaaaa cgctgaagca
     6781 cttgaaatta aaggtggtgc aatcgaaggc gctgtcgcat ctaaagaaga gattcttgca
     6841 cttgcaactc ttccaaaccg cgaaggactt ctttctatgc tcctttctgt acttcaagcg
     6901 ccagtgcgca acgttgctct tgcagtcaaa gcggttgcag aaagcaaaga agacgcggct
     6961 taatcttaag ctacacagcg tagcctagct acgaaaaaaa ctattataaa atttaaaact
     7021 tatttggagg aaataacaat ggcattgaac attgaaaaca ttattgctga aattaaagaa
     7081 gcttcaatcc ttgaattgaa cgaccttgta aaagctatcg aagaagaatt tggtgtaact
     7141 gcagctgctc ctgtagctgt tgctgcagct gatgctgctg atgctggtgc tgctaaagat
     7201 tcattcgacg ttgaattgac atctgcaggc gacaaaaaag ttggcgttat caaagttgta
     7261 cgtgaaatca ctggtcttgg tcttaaagaa gctaaagaac ttgttgacgg tgcaccagca
     7321 cttgttaaag aaggcgttgc aactgcagaa gctgaagaaa tcaaagctaa attggaagaa
     7381 gctggagctt cagttactct taaataagag gcatatacca attagaattc ggaatactat
     7441 agtatcagcc ttttagaatc gtgaacacat tttagaaact gataaattaa tttagtttcc
     7501 taccaaaaac cctaccaaaa attctttggc agggtttttc tttttaataa aattattttg
     7561 gagaacagtt gaatattgtt ctcctttttt tattttcagg agggaaaatg acaaaagaat
     7621 tacaatcatc acgctatatt gtcatttcat ttttagtacg tgaaatggga attgatattg
     7681 ttgaagccat ctctcttatg gctgaattag aaaaaagtgg cttggttcga ttggaatcaa
     7741 gtggagattt aatactcaaa gaacttggag gagcgctatg aaacgaatta ccgcaaatca
     7801 ataccaaact tcagaacggt attacaaatt acctaaaatt ctttttgagg atgagaaata
     7861 tatggatatg aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt
     7921 gtctttgagc aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc
     7981 aaatttgatg gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag
     8041 taacattttt agatgattac cataaaaaac acaactaccc actattttac gagccctatt
     8101 ttcaaaacgt tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg
     8161 tagatgatca tcaaaatctt gtttttgttt tatatggaca aggctatcga gccgagggaa
     8221 aagagggaat acttacaacc caagtaactg taaaagctta tgatgaagac aagcaaccga
     8281 ttaacttcgc aaatttatta gattccttaa tcgtctcaga gtatcaaatg gaaccgaatc
     8341 tttgggaggt ctcccatgat tgatctctat ctaagtaaaa atagccaaag aaatcaactt
     8401 cttttagact tcttccaaaa ctatggcatc gaggtatctt gtcattcagt ttctgaaatg
     8461 acaaaggata aattaattga gatgatgagc tattcttcag attgttttga gtttttatct
     8521 cccaatttat tacgatttaa gaaccgtgac aatctaagat taacggattt cgttgagata
     8581 attttaaaaa atcctgaact aaccatcgga cttccttttg tggtttcaaa taagcgggtt
     8641 tatccaagtc tgaatttgga agaggctaga gctctattgc caagagatac gaaacaattg
     8701 atttacatgg cacaaacaca ttatttatct aactaaagga gaagtaatat ggctgaacga
     8761 ttttgggaga acttgtccat tattttggct gaaagaaata tcagctggat tgagttaacc
     8821 agaaaaatgt ttgcgggaga gtttcactat ccaagtgaat tgaatcgttt atatcaaaag
     8881 attcgccact acaagatgga acaacgaatg cctcaaagtc catgggtaga aaggattgtg
     8941 cagatattag atttagatta tgaagattta tttcggaggt aactatgaaa agaataattc
     9001 cagtttatat attccaacaa gtaaatgtcc tattggtatc tctatactta ttgaaatttc
     9061 tttgtatcgg tgagttaact atactacagg ttctctatgg tgcgtctctt ttttcttttt
     9121 tatggatgta tggtcaacga aaacaagtgg tcaaggtcaa tatgaaaact aggatgaaat
     9181 gccttggtat tggactagct agtctactga ttataagtct atgttttagc ctgattcatg
     9241 ctcaaggaag cacgaatcaa acaaatttaa ttggccttca acatcaagtt ccttggtttt
     9301 catttttatt gttcttaatc aatgcgagta tggttgaaga atttctgtat cgtgaaattt
     9361 tatggaactt ggttagaaaa ttagatattc gagttgcttt gacaagtgtt ttatttgcct
     9421 tagtacatca tccaggaacc attctagctt ggtgtctgta cgtttcactt ggaatgtttt
     9481 taggtatggt gcgctataaa tctgacttat ggggaagtat ggggttacat ttggtgtgga
     9541 actttttagt ttatagtttg ctgctttttt aaaataggtg acctgattta tctcataaat
     9601 ctgtagtttt tatgggattc tcttt
//
LOCUS       DAVMCN010000065         9480 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVMCN010000065 DAVMCN010000000
VERSION     DAVMCN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.066"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            129..1622
                     /locus_tag="VYP85_001799"
     CDS             129..1622
                     /locus_tag="VYP85_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1882270.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2528
                     /locus_tag="VYP85_001800"
     CDS             1635..2528
                     /locus_tag="VYP85_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1882271.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNELVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNHNLLVR"
     gene            2602..5952
                     /locus_tag="VYP85_001801"
     CDS             2602..5952
                     /locus_tag="VYP85_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1882272.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYCATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISDQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            6223..6468
                     /locus_tag="VYP85_001802"
     CDS             6223..6468
                     /locus_tag="VYP85_001802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882273.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKATLTRIEEIFEEYKSS"
     gene            complement(6562..7032)
                     /locus_tag="VYP85_001803"
     CDS             complement(6562..7032)
                     /locus_tag="VYP85_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1882274.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(7049..9322)
                     /locus_tag="VYP85_001804"
     CDS             complement(7049..9322)
                     /locus_tag="VYP85_001804"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1882275.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         3044 a         1525 c         1997 g         2914 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt
     1681 acgcttttaa atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc
     1741 gagatgtaga aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc
     1801 ttattaaaaa tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg
     1861 agggggattt agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg
     1921 tagatgaagg ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga
     1981 ccccttttgt tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat
     2041 tgcctaataa actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt
     2101 atgattttcg taaaattcaa tcagaaaaat ttaacgagct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     2221 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     2281 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     2341 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     2401 caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     2461 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcac aatttgcttg
     2521 tgagatagct ataaaagtgt ggagaaatag cttgaaattt agtataatat agctaaacta
     2581 tttgtttaaa gtgagaaaaa aatgggaaat tttagctttc ttttaaaaaa tgacgaatat
     2641 gaatcttttt caaaaccttg cattgaagct gaaaatatga ttgctacatc aactgtggct
     2701 actgccttta tggcgcgtcg tgctttggag caggctgtcc attggatata tagtcacgat
     2761 tcatatttag aagctcccta ttgtgctact ctatcttctt tagtatggga tgatgatttt
     2821 agggatatcg tagattctga actccacaag cagatagttc tgttgattcg gtggggaaac
     2881 catgctgctc atggtggtga aattaaggaa cgagaagcga ttttagcttt acatcatttg
     2941 tatcagtttg ttaattttat cgattattgt tacagcaatg aatttgtgga gcgttatttt
     3001 gatgagaagt gtttaccact ttcagcaaac atcaaatacc gagaaactcc acaatctatg
     3061 ataaagttac aagacagttt accagaactg cctgattttc atgaacagat ggctgctcag
     3121 tccgtagaag ttcaagagac ttatactgaa aaacgtgaga ctgcagcgca acggcaagat
     3181 gtgcctttcc atattgaaca attatctgag gcagagacaa gaaagctctt tattgatatc
     3241 gatctccgtt tagcaggatg gatatttgaa gaaaactgtc gtgttgagat agccgttgat
     3301 ggtctcaagc acggttcagg aattggttac tgtgactatg tactttatgg taaaaatggg
     3361 aaaattttag cgattgtgga ggctaaaaaa gcctctgtca atccagaagt aggggaagta
     3421 caggtcaaag aatatgctga agctttggag aaacatatcg gctatcagcc aatttgcttt
     3481 attacaaatg ggttgaagca ctatatactt gatggtccga accgccgcca gattgcaggc
     3541 ttttactctc aagaagaatt gcaattagtg atggatagac gtcatcttca aaaaccgctt
     3601 gaggatattt ctagtaaaat tagggacgat atttccgggc gtcactacca aaaacatgcc
     3661 attgcaagcg tttgtgaagc tttctctaat catcgtagac aggcactttt ggttatggca
     3721 actggggcgg ggaaaactcg tacagcagtt tctctagttg atatcttatc acgtcataac
     3781 tgggtaaaaa acgttctctt cttagccgat agaacttcct tggttaagca agcctatgat
     3841 tcgtttagaa aattactccc agatctttcc gtttgtaact tcttagaaga taaagaagga
     3901 gctcaatcaa gtcgtatggt cttttcaact tatccgacca tgattggagc gattagtgat
     3961 caagaagaag taaatcaacg cccttttact gttgggcatt ttgaccttat cataattgac
     4021 gaatctcacc gttctattta tcagaaatac aagtccattt ttgattattt tgatgcaagg
     4081 attgtaggct taacagctac tccgcgtcaa gatttagata aaaacaccta tggattcttt
     4141 aatttggaga atggggttcc aacatatgca tatgatttgg aagaggctgt taaagacgga
     4201 tatttagtag cctatcattc tatcgaaacc aaactgaaac tacctacgga tggtctacat
     4261 tatgatgatt tgtccgaaga agaaaaggaa cattttgata gcaaatttga agacgatagc
     4321 tgtgaaaaag atattgatgg gagtgtgttt aattccttta ttttcaataa aagtacagta
     4381 gaaattgttt taaatgaact catgacaaga ggaattcaga cagcctcggg tgatgaaatt
     4441 ggtaaaacta ttatttttgc taaaaatcat gaccatgcgg aatatatcag aggtattttt
     4501 aacaaccgct atcctgaaaa agggagcgac tatgctcagg tgattgatta tagtattaag
     4561 cattatcaga ccttgattga tgattttaaa attaaggaga agtatcctca aattgcgatt
     4621 tctgtcgata tgttagatac aggtattgat gtaccagagg ttgttaattt agtcttcttc
     4681 aagaaagtac gctctaaaac taagttttgg cagatgattg gtcgaggaac ccgtctatgt
     4741 aaagatttat ttggacctga gcaggataag gaaaacttct tggtatttga ttatggggac
     4801 aattttgatt attttcgtgc agatccaaga gatggagagg gtcgtcacat tgtttcgttg
     4861 actcagcgtt tatttaatat caaagtggac ttgattcgag aacttcaggg acttcaatac
     4921 caagaagatc agtttgcgag agcataccgt cagcagcttg tctcggaact tcaaggtcgt
     4981 atagagagct taaatgagtt ggacttcagg gttcgtatgg ttttagatac agtttatagc
     5041 tataggaaat tggaaagttg gcagaatcta actgctgtta caagtgaaac cattcaaaaa
     5101 aatctctctc cgcttttatt tgatgaagat aaagaagatg agatggccag gagatttgat
     5161 ttgtggttgc ttcatattca gttggggcaa ctgacagcta aatcttccac tgttcatatt
     5221 tcccaagtga tgaagacggc tagagctctt tctgctattg gcaatatccc gcaggttttt
     5281 gagcaggctg aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg
     5341 tctgatttgg aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca
     5401 gaccgtaaac cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc
     5461 acagcatttt tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg
     5521 aaaactcatc tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct
     5581 gatgatatgc ttgcacttga aaaattgctc tgggaaaaat taggtagtaa agcagactac
     5641 caaagtcatt atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat
     5701 agagagtctg ccaatcgtat tttttctaaa tttttgtcgg atgagaatct taatgccagg
     5761 cagatttcat ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg
     5821 aaagtgttaa cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac
     5881 caactaccag tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga
     5941 gaagcggctt aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt
     6001 agaaatttat gctatatatg agaagtttta ttaggaagaa tgtcatcgtt ttcctataat
     6061 acagtatcag ttgttaagtg gttgataaat ttcaaagtag atacttgtac cacgatgttt
     6121 gttgatcgag ttattaacaa aagagctact ttgattttaa agaaatagaa aacaaaaagc
     6181 tgagcaagaa ttcaattgca ggagaaaatg aaataatact caatgaaaat caaagagcaa
     6241 actaggaaac tagctgcagg ctgctcaaaa cactgttttg aggttgtaga taagactgac
     6301 gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa
     6361 catggttttg aggttgtaga tgaaactgac gaagtcagta accataccta cggcaaggcg
     6421 acgttgacgc ggattgaaga gattttcgaa gagtataaat cttcctagga tagagcaaaa
     6481 cgcatagtat caagggtttt ctgatgttaa agactttcta ccaggttttt taaaagcata
     6541 attgttagtt gtagtcattt attattcttc aaagaaaaat ggtggggcga attttttcag
     6601 ttcttcaaag cacttttgag cagtatctgc atcttcacag atgataagac agacatcatt
     6661 accacaaagg gtagcgatag cgtcagggaa gctcaaagta tcaatgatag aaccaaagga
     6721 ttgagccagt ccaggaaggg tttttagtag gacttggtgt tgaactgggc gcatccagac
     6781 aagggcgtct tccatgtaga gttcgagacg tttttcccat tttgagatgg aaccattgtt
     6841 aagaacataa taagcgctat cttcttcgcg gacttttgat aggttcatat ttttgatgtc
     6901 gcgtgagagg gttgcctggg ttacttgaat gtcgttctca gcaagaaggg cttgcaactc
     6961 agcctgtgta tgaatcttgt tttttgtgat aagagcgcgt ataagttggt ggcggtgttc
     7021 tgatttattc ataataatgt aactcctttt agcaaggtaa ggtaagcatg gactgagcga
     7081 ggtcgacagt caagtggtag tctgtattgt cacggatggt gatttcaaag tcagtagtat
     7141 agaggactaa acggagagtg tctccttctt ttagcttgta aatagttggc tgcagttcaa
     7201 attgaacgtc catccattca tctgcagtaa tatcctctac taacagtaaa tcatttctat
     7261 tttgtaaatt aaggtaacct tttgtcacga ctcgttgtgc ctctggtcta aatggcaatt
     7321 cacagagatt ttccaacatg tgatagcgac cgttatcaat ggttctagca cttaaaatag
     7381 ctggataagg ttgtaggtat ttcttttgcc caaattctag cagttgggca gataagagcc
     7441 ccttgtttgt actggatttg atacgaagat tgagctgagc gcgaccgttt aggtggagat
     7501 ctttagtcac aggaaggtta atagtaatct gattggcttt cccttgatag agctctgtat
     7561 tgaaggtttg gtatgtctta ccatagcgct caaaatcctt atctgggtac tggttttgaa
     7621 tagcttgctc ttcttgacca agtgagaagg tttcacagtt ttcttgccca ccgaagttat
     7681 caagtgataa ccaagtctgt ggagctgtat tgtcctgcca gataacagta ggaagttgaa
     7741 agtctgtttc ctgtcctagt aatttcttgg tcaataaggc atttatggac tcacggaagt
     7801 caattgattg ccaattgttc atgtaaacat gagcaccatt atggaaaaag agatgcttgt
     7861 gtatatgagt aggaagagca tggaacatct ggtaaacatg aagtggtttg acattccaat
     7921 cctgagaacc atgagtaaag acaacctctg cctttacttt atgggcattg agcagataat
     7981 tgcggtcatg ccaaaactga ttgtagtccc cagtttttcg gtctagctga gctttcactt
     8041 tttctaagtc agcttggtga gcttcattgc cacggatata gtcgccagct aagagattac
     8101 gagaataggt taactcagca agggagtcaa agtcctcacc tggataacca cctgggctag
     8161 tcaccagacc gttttcacgg tagtagttgt accatgatga aattcctgcc tcggcaatga
     8221 taacttctaa accatcgact cctgtagtcg caagaccatt ggacatggta cctagatagg
     8281 aaagtcctgt tgtagcaact tttccgtttg accaatcagc cttgacttga cgctggcgcg
     8341 tgtgatcagt aaaggcacgg caacggccgt taagccaatc gatgacattt ttataagcct
     8401 cgatttgctg gtagtctcca ttagtcatga aacctgtcga gtctttggta ccaacacctg
     8461 agacatagag attggcaaag cctctcggaa ggaagtagtc gtttagtgta tagctagagt
     8521 tgatgtgagt tagcttttcc tcagcctctg ctataagctc agctttacct tggggttgga
     8581 cgagatttag ttgaggtttc tctagctcaa tcttgtgagg aagcttaacc tcaagctcgc
     8641 cctccatctt gtagagagcc ttgtcactag ccttgtcatt ggttccctga tgataagggc
     8701 tggctgtcat gatggcaggg atttttccat caaaacgagg gcgaataatg ctaaccttta
     8761 ctaggtctga tagccctttt tggtcagtat cgacacgaga ctcaacgtaa acgacttcac
     8821 gaatgacatc ctggttagaa aaagtagcca aactcttgcc gttaaagtag tggtagtcat
     8881 tatcctccgg aataagacca tcactaacaa gttggtcgat aagagtattt ccttttttgg
     8941 tgcgagtatt gagtaactga tagagatttt caatcaagtc accatatata atgggaaatc
     9001 cagtttcttt acgaaaaacg tcactatctt cgaagtcaac caaataagaa aagcctaaaa
     9061 gttgaaaagc aacagtataa aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg
     9121 tcagcaggtc tgttttttta tcagctgcta ggatagaaag tgggtagttg gtgtcttgat
     9181 aagtgaaaaa gaaacgacgt aaaaaggttt caagtgagtc tttgtgattg gctgtatttt
     9241 gtaaatcaaa gccacatttt tttagttcag ataagacatt ttcttttgga aaattgatat
     9301 aactatattg attaaaacgc atagaacctc catatagaat gacagttaag gttattatat
     9361 caaaaaaaaa gcagaaaggg aattgttaac ttcaaaagga aataatccaa taaaaatgaa
     9421 taaagtacta aattcaatat agagaacaga gtaacaataa gaataaatag atagggtata
//
LOCUS       DAVMCN010000066         9408 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVMCN010000066 DAVMCN010000000
VERSION     DAVMCN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.067"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..1078
                     /locus_tag="VYP85_001805"
                     /pseudo
     CDS             1..1078
                     /locus_tag="VYP85_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1205..1408)
                     /locus_tag="VYP85_001806"
     CDS             complement(1205..1408)
                     /locus_tag="VYP85_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882276.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1401..2483)
                     /locus_tag="VYP85_001807"
     CDS             complement(1401..2483)
                     /locus_tag="VYP85_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1882277.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSAEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2609..3391)
                     /locus_tag="VYP85_001808"
     CDS             complement(2609..3391)
                     /locus_tag="VYP85_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1882278.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3391..4734)
                     /locus_tag="VYP85_001809"
     CDS             complement(3391..4734)
                     /locus_tag="VYP85_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1882279.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4833..6149)
                     /locus_tag="VYP85_001810"
     CDS             complement(4833..6149)
                     /locus_tag="VYP85_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1882280.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6342..7568
                     /locus_tag="VYP85_001811"
     CDS             6342..7568
                     /locus_tag="VYP85_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1882281.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7767..9341
                     /locus_tag="VYP85_001812"
     CDS             7767..9341
                     /locus_tag="VYP85_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1882282.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2779 a         1814 c         2069 g         2746 t
ORIGIN      
        1 tacggtctcc caagtcgtac gatacttctt aactggctag cacaatacag aaaaaaacgg
       61 gtatactatt gttgagaaaa caagagggag agtacctaaa atgggacgta agccacaaaa
      121 gagacctgaa gagaggacag aattagaacg tcttcaagca gaaaatgagt acctgagagc
      181 ggagaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaaa aagagaaaga
      241 agaaagacag aaattgttca agaattaatg actgagtttt cgttagatct tcttctaaaa
      301 gccattaaac tagctcgttc gacctactac tatcacttga aacagctaga taaaccagat
      361 aaggaccaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa gggaaattat
      421 gcttatcgtc ggatttattt agaactaaga aatcgtggtt atctggtaaa ttataaaaga
      481 gttcaaggct tgatgaaagt actcaattta caagctaaaa tgcgacagaa acgaaaatgg
      541 caagaaggca gagaatctca ttcaaggcca atttgaaggc tctaaaacaa tggaaaagtg
      601 ctacacagat gtgacagaat ttgccattcc agcaagtact caaaagcttt acttatcacc
      661 agttttagat ggctttaata gcgaaattat cgcctataat ctttcaactt cacccaactt
      721 agaacaagta caaacaatgt tggaacaggc attcacagag aagcactacg agaatacgat
      781 tctccatagt gaccaaggct ggcaatatca acacgattct tatcatcggt tcctagagag
      841 taagggaatt caagcatcta tgtcacgcaa gggaaacagc caagacaacg gtatgatgga
      901 gtccttcttt gggattctga aatcggaaat gttttatggc tatgagaaaa catttaaatc
      961 acttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca acaaacgaat
     1021 taaggtaaaa ctaaaaggac ttagtcctgt gcagtacaga actaaatcct tcggataaat
     1081 taattgtcta actgtttggg ggcagtacat tcaacacctg atactatgcg ttttattgtg
     1141 ggaagatttt cctcattttc tagtgaaatt gaactttttc taacatcttt tgatagatga
     1201 cttcttaatc aattatcatt tccattgttg tttcttgggg tttcatccct tgtctttgat
     1261 aaaagcggag agcaccctcg ttatcattcc agacacttag ggttagatta ttgcagccaa
     1321 tttctttagc ataatagcag aaaaatgaca ataaaatagc ccctagatat tttgaaagga
     1381 aagcataggg gctatatagt ttaatcaaaa taaagcaaat ctttgctggt gcttgtaaag
     1441 aggtcgaagc catccttggt aacaacaccg cagtcttcaa tacgaacacc gactttacca
     1501 gggatataga tacctggttc agcagagaag cacatgcctt cttcgatgac catgtcgttt
     1561 ccttccatga tagatgggaa ttcatggaca tccataccga taccatgccc gagacggtgg
     1621 ttgaagtact caccataacc agctttttcg atgacctcac gggcagcgcg gtccacttca
     1681 tgagcagtca cacctggctt gataaagtca agagcagctt gttgggcttc aagagtcaag
     1741 ttgtaaatat ctttcttgaa ttggtctggt ttgccgacag cgactgtacg agtcatatct
     1801 gacgcatagc cattgaccag aacacccagg tcaaagagga gaagagcatc attttcaacc
     1861 ttattagctg ctggaatgcc gtgtggattc gcagcattat caccagtcaa gaccatggta
     1921 tcaaagctca tttcataacc ttcacgtttc atggcaaagt cgatttgtgc gatgatatct
     1981 gtctcagtct tatcaagaga aatattgtca aaaccaacat gaacagcctt gtcagcataa
     2041 agacctgcaa ccatcatttt ttgcacttca tcagctgatt tgatgaggcg catgcgttgg
     2101 atacgaggag tgaggttgtc aaactcagca gtctcaaaaa ctgttttcaa accatggtat
     2161 ttggtcaaga tgagattgtc aaactcaaca gcgacacgtt tgaagtcaag ttgtggaaga
     2221 gcatgtttga ttttttgcca tggattttca gaatcgacat agcccactac tgggaaggaa
     2281 acggtgctac ttgcacgttc tacttcaaga gctgggacaa agaggagagg ttcctgatcc
     2341 gctaggacaa agaggaacat ttggcgttca tggggatcac tgtaaaaacc agtgaggtaa
     2401 ttgattgtga cggggtcaga tacgacagcg acgtctagtt tttctgattc aagatatgtt
     2461 aggatttgtt gtaatttaga catatgctac cttctttcta cccctctatt ttggcaaaaa
     2521 atgagagaaa atgcaaggga gaagggtaaa agaaaagaca aaaaactccg acaagataac
     2581 ggagttcttt gatatcattt tcctttgttt aagaaaagtc agccttgctt ttgacgtcac
     2641 tgtactcttc agcgatttct tggctgagga tatcctcata ggcagggagt tggatgtcct
     2701 gaccatattt cttcttgagg gcagtagtaa ctaggcgata agccagattg gcattacgag
     2761 agaggatagg cccgtggaag taggaaccaa agacattctt ataatgaacc ccttcaccga
     2821 ccttttcttc gttgtttcca tttccataga caacctgtcc cagcggtttt tggtcatcag
     2881 agaggaaggt acggccttgg tgattttcaa atccatagta ggtttcatcg aaatcttcat
     2941 tgtgaatctt gatgtcaccg ataaaacggt tattggtctg gttgagcgtg tagtgtccca
     3001 tgacccctag cccttcgata cgttttcctg aagcttcaac ataatattga cccaatagtt
     3061 ggaaaccacc gcagatagcc agaactacac cgtcgttttg gatgtagttg tcaatgctct
     3121 cttttttagc aggtaggtcg tctgcaatga tactttgttc aaagtcttga ccaccaccga
     3181 aaaaggcgat gtcgtagtga ttttcatcaa agtcatcatg gagagaaacg atgtcaacgg
     3241 tcacatgggc tcccagtttt tcagccacat acttgagcat gaggatgttt ccattgtccc
     3301 cgtaggtatt catgagattt ccgtagaggt gggcaatgtt gagctgatag gggtaattgc
     3361 catcttttga ggaaagtgaa gtataaacca ttagttcatc tcctttctaa caatctgacg
     3421 actagccagc agttcacgaa attccagcat ggcagtataa gttgccagaa tataggcatg
     3481 cttgcagtct tgattctcaa tggtcttgag aacttgctcc agattactcg tttcagtgat
     3541 tttctcagct ggatagccag tcactcggag gcgacgagcg atttcagaat gacgaacacc
     3601 gccagcgttg atttcaggaa tgtccatgtc agtgatttgc tcaaagtctg catcccagat
     3661 ccagctagtg tcaattccat ctgcatagtt ggcattaagg aggacagata ggctaaatgg
     3721 ataaggtgct agtttgatca tttcgatagc ttgggttgca ccgactggat ttttaatcaa
     3781 gacaagggta cattccttgt caccgatatg aaaggtttct tggcgtccaa agacagcacg
     3841 gctcttgtca aatccctgtt tgatgagttg cgaatcggca cctaggaaac gggcgatggc
     3901 cacagcagct agggcgttat atatattata gagcccgccg atttggatac cgtattcttg
     3961 gccgtctatg acaaagcgag agcgattgtt ggtcaactca accaattttg tcaaacgata
     4021 gtcgagatca ggacgtttac atccacaacc ttcacagata taggcaccca agtttgcata
     4081 ggtattatgc tcatatttga ggatgccttg gcagtcagga cagagaatcc cttcggtatt
     4141 gtagtgagcc agttgggctg gtcctttttc caagtcaaaa ccaaaatact ctatagggtt
     4201 tggaatagtt ggcttgtaga aaagtggact gtctccgtta aggagaacag tagcagttgg
     4261 aactttccga atggcatcca atatcatgtt ataggtagta tagatttcac cgaaacggtc
     4321 catctggtca cggaagatat tagtaatgac aaaaagacta ggctggatat agtcacagat
     4381 acgagataga ctggcttcgt caatttcgag gacggcaata ttttttccag ttttagaaga
     4441 tttggctgtt aggaaggttg ttgcaatccc tgtaatcatg ttggcaccgc ttgggttggt
     4501 tagaacttga ccataaacct cttttaaaat gccgacagtg agggcagttg tcagggtttt
     4561 tccatttgtt ccagtgacaa cgacaatctc gtagttctta gctaggtttt gtaaaatatc
     4621 tttatcaaat tgaagggcga ctttacctgg gagcgtactt ccacgtccaa gacggcttaa
     4681 aacgaagtgg gaagaacgcc cagcaagaag gcccaaagta gtttttaagt tcatgtttct
     4741 attatatcac aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca
     4801 aagagggctg tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc
     4861 tcagccaagg ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg
     4921 tccatagcaa cagtaatgat gttgatgatt tcttgagaac cttctgagaa gatgcttgca
     4981 ccaagaattt cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca
     5041 tttacgtgac cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc
     5101 aaatcagctg cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata
     5161 gtatttggca cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg
     5221 taaacaacac ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct
     5281 ccaactgcaa agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca
     5341 cgttcagtta gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt
     5401 ccagttgcgt agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact
     5461 tggtcaccgt cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct
     5521 tcttccatgt attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta
     5581 tccaaggcat ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca
     5641 agaccgatat ttccgccacc aaggactcca agtttttcag gtaatttgtc caagctttgg
     5701 atacctgttg agtcaaagat gtttttgctt gtagcaagtc caggaattgg caagacgttt
     5761 gaaacagcac cagtgttgat gacgattgtt tcagcagtca gttctttctt ttcatcacca
     5821 gcttggattt cgatgacttt atttgaaagg aagtgagctt ccgcatcaaa gatatctacg
     5881 cctgtaccag caacagtcgc atagttttta ccgttgaggc gaccagtgat cgtgttttta
     5941 gtagcaatca cttcttcaaa agacaagtcc ttttcagcag caactagcaa ggttttagtt
     6001 gggatacaac caatgttgat acaagttcca ccgtacatag ccttgctgcg ttcaacgagg
     6061 gcaacttttt tgccagctga agccaattta cctgctagtg ttttaccagc tttaccaaat
     6121 ccaataacaa ttaaatcgta tgttaacatt tatcttcctc ctattcgaat ttcattctag
     6181 cacaagaaaa aaacttttgc acaattctgc tacggaaaag acagaaaaag ataaaaacgc
     6241 tttccagaca aaaaactagt aattttttga caagcttgat aaactaaaat cctatctatt
     6301 tttatataag aaagaataaa tgttcgaaaa taggaggttt tatgaaatcg aatcgttata
     6361 ttattgcctt tgctggggtc attttacact taatgctggg ttcgacttat gcttggagtg
     6421 tttatcgtaa ccctattatt gaaaaaacgg gatgggatca ggcttctgtt gccttcgcct
     6481 ttagtctagc aatcttttgt ttgggcttat cggctgcatt tatggggcgt ttggtagaaa
     6541 aatttggtcc gaaagtcatg gggagtctat ctgcttttct atacgcaggt ggaaatatct
     6601 taacaggatt tgcaatagac cgtcaggaac tgtggttgtt gtatctagct tatggcattt
     6661 taggtgggct tggtttggga gcaggctata ttacccctgt gtcaacgatt ataaaatggt
     6721 ttcctgataa acgtggtctc gcaacaggtt tagcgattat ggggtttggt tttgcttctt
     6781 tattgactag tcccatagcg caacacctca tcgcaggggt agggattgta gaaacttttt
     6841 atattttagg agcaagttac tttattatca tgctcctagc ttcacaattc attaagcgtc
     6901 caaatgagca agagcttgca attttatctt cttcagggaa agaaaaaaca gcctctttga
     6961 cgcaaggaat ggctgcaaat caggctctaa aaagcaatcg gttttatatg ctttggatta
     7021 ttttctttat caacatagct tgtggtttag gcttaatttc agcggcatcg ccaatggcac
     7081 aggagatggc tggcttgtct acaagtcatg cagcagtaat ggtgggtgtt ttggggattt
     7141 tcaatggatt tggtcgcttg ctctgggcga gtttgtctga ctatatcggt cgccctctaa
     7201 cctttagtat attactgctt gtcaatcttt tcttttctct ctcactttgg ctctttacag
     7261 attccgtttt atttgtagtt gctatgtcta ttttgatgac ttgctatgga gctggttttt
     7321 ctttgattcc agcttatctc agtgatattt ttggaaccaa ggaattggcc gctctgcatg
     7381 gttatatttt aacagcttgg gcaatggctg gtttagcggg acctatttta ttagcagaga
     7441 cttataaaat ggctcattcg tacacacaaa ccttgttcgt ttttctcatt ttatacagta
     7501 tcgccttggc tttgtcttat tatctaggtc gttcaatcaa aaaagaaagt caaaaaccgc
     7561 ttacatgatt ttctgtagaa atggggctat cttttgctct ggtcttgtgt tatactagat
     7621 aggttgcaaa gaaaacagta cttttctttt gtggaaaaga agcaacacga ttttatatct
     7681 agttatatga aaatacgtca taaaaagaaa agtataaact aagccctata gggtggcttc
     7741 gcaccacctt tagaaagaag aataacgtga aatttaatga attaaacttg tctgctgatt
     7801 tgctagcaga aattgaaaaa gctggttttg tagaagctag tcctatccaa gaacaaacta
     7861 ttcctttggc ccttgaaggc aaggatgtta ttggtcaagc tcagactggt acaggaaaaa
     7921 ctgcagcctt tggcttgcct acccttgaaa aaatccgtac agaagaagcg actatccaag
     7981 ctttggtcat cgctccaact cgtgaactag ctgtccaaag tcaagaagaa ctcttccgct
     8041 ttggtcgtag taagggagtc aaagtccgtt cagtatatgg cggatcaagc attgaaaaac
     8101 aaattaaggc tcttaaatct ggtgcccata tcgtggtggg aactccaggt cgcctcttgg
     8161 acttgattaa acgcaaggcc ttgaaattac aagacattga aacccttatc cttgacgaag
     8221 cggatgaaat gcttaacatg ggcttccttg aagacatcga agccattatt tcccgtgtac
     8281 ctgagaaccg tcaaactttg cttttctcag caactatgcc agatgccatc aaacgtatcg
     8341 gtgttcagtt tatgaaagcc cctgaacatg tcaagattgc ggctaaggaa ttgacaacag
     8401 aattggttga ccagtactat atccgtgtta aggaacaaga aaaatttgac accatgactc
     8461 gtctcatgga tgtggcacaa ccagaactcg ctattgtatt tggtcgcacc aaacgccgtg
     8521 tggatgaatt gactcgtggt ttgaaaattc gtggcttccg tgcagaagga attcatggcg
     8581 acctagacca aaataaacgt cttcgtgtcc ttcgtgactt taaaaatggc aatcttgatg
     8641 ttttggttgc gacagacgtt gcagcgcgtg gtttggatat ttcaggtgtg acccatgtct
     8701 acaactacga tattccacaa gatcctgaga gttatgttca ccgtatcggt cgtacaggtc
     8761 gtgctggtaa gtcaggtcaa tctattactt ttgttgctcc aaacgaaatg ggttaccttc
     8821 aaatcattga aaacttgact aagaaacgca tgaaaggtct caaacctgca agtgtagaag
     8881 aatccttcca atcaaaaaaa caggtagctc tcaagaaaat cgaacgtgat tttgcagatg
     8941 aaaccattcg tgccaacttt gagaaatttg gtaaggatgc tcgcaaattg gctgctgagt
     9001 ttactccaga agaattggca atgtatatct tgagtctgac agtccaagac ccagatagcc
     9061 ttccagaagt ggagattgca cgtgaaaaac cactaccgtt taaaccatca ggtaatggtt
     9121 tcggtggtaa agctaaggga ggtcgtggag gccgtcgtgg ggacgaccgt cgagagcgtg
     9181 atcgccgtgg caatggtcgc cgtgatgagt tcaaaaaagg aagtcgtggc aacgatcgtt
     9241 ttgataagga aaaacgttac cgtaaggata ataaaaaacc acgcaatact ttaagcgaaa
     9301 agcaaacagg ctttgttatt cgtaacaagg gcgataaata agaaaaagcg gttcaaaatg
     9361 aatcgctttt ttatataagg agaccgaatg tgaaaagaca aataaaat
//
LOCUS       DAVMCN010000067         9032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVMCN010000067 DAVMCN010000000
VERSION     DAVMCN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.068"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            146..3247
                     /locus_tag="VYP85_001813"
     CDS             146..3247
                     /locus_tag="VYP85_001813"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1882283.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3330..4337
                     /gene="pfkA"
                     /locus_tag="VYP85_001814"
     CDS             3330..4337
                     /gene="pfkA"
                     /locus_tag="VYP85_001814"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1882284.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADSKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4396..5901
                     /gene="pyk"
                     /locus_tag="VYP85_001815"
     CDS             4396..5901
                     /gene="pyk"
                     /locus_tag="VYP85_001815"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1882285.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6592..6817)
                     /locus_tag="VYP85_001816"
                     /pseudo
     CDS             complement(6592..6817)
                     /locus_tag="VYP85_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(6975..7229)
                     /locus_tag="VYP85_001817"
     CDS             complement(6975..7229)
                     /locus_tag="VYP85_001817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1882286.1"
                     /translation="MGTKIGISKNTIGNYEKRVRSTKKNTIFDLVKVFSSLIDALFSP
                     VQKDSPSDIQSIYDQRAPSRQGKVLTYAERQLYDQKNEVS"
     gene            7665..8537
                     /locus_tag="VYP85_001818"
     CDS             7665..8537
                     /locus_tag="VYP85_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1882287.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPTDDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8670..9027)
                     /locus_tag="VYP85_001819"
                     /pseudo
     CDS             complement(8670..9027)
                     /locus_tag="VYP85_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         2771 a         1575 c         1937 g         2749 t
ORIGIN      
        1 acaatatagt ataaatataa aaatgatgac aaaaatacaa atggatagaa aataaattag
       61 taagctgatg aaatttttct caagagaagc catttatagg tgaaaatggt ataatatagt
      121 gagaaggata gaggagaagt gtaaattgat cgcacaacta gatacaaaaa cagtctatag
      181 ttttatggaa agcgtcattt cgatcgaaaa gtatgtgaga gcagctaaag aatacggcta
      241 cactcatttg gctatgatgg atattgacaa tctttatggc gctttcgact ttctagagat
      301 tacaaaaaaa tacggcattc atcctttgct agggcttgaa atgacagtgt ttgtagatga
      361 tcaggaagtg aatttgcgct ttttagctct atctagtgtg ggctatcagc agttgatgaa
      421 gctttcgaca gccaagatgc agggggagaa aacttggtca gtcctgtccc agtacctgga
      481 ggatatcgcg gtcattgtgc cttattttga tagagttgag tcgttagaac taggctgtga
      541 ttactatata ggggtttatc cagaaacact agcaagcgaa tttcatcatc ctatcttacc
      601 tctttatcgg gtcaacgctt ttgaaagcag ggatagagaa gttcttcaag ttttaacagc
      661 gattaaagaa aatctaccgc tcagagaagt tcccttgcgt tcgagacaag atgtctttat
      721 atcagcaagt tctttagaga aactattcca agagcgtttt ccgcaagctt tggacaattt
      781 agaaaagctt atttcaggca tttcttacga cttggatact agtctgaaac tgcctcgttt
      841 taatccagct agaccagcag tagaggagtt gagagagcgt gctgaactgg ggcttgttca
      901 gaaggggttg actagtaaag aatatcaaga tagactagac caagaattgt ctgttattca
      961 tgatatgggc tttgatgatt atttcttggt tgtttgggat ttgttgcgtt ttggacgatc
     1021 gaatggctat tatatgggaa tgggaagggg ttctgcagta ggcagtttgg tttcttatgc
     1081 cttagacatc acggggattg acccagtaga gaaaaatctg atttttgaac gctttcttaa
     1141 tcgtgaacgc tataccatgc ctgatattga tattgatatc ccagatattt atcgtccaga
     1201 ttttatcaga tatgttggta ataaatatgg tagtaaacat gcggcacaaa tcgttacttt
     1261 ttcaaccttt ggagccaagc aagctcttcg agatgtcttg aaacgctttg gtgtgccaga
     1321 gtatgaatta tctgcaatta ctaagaaaat cagttttcgt gacaatctta agtcggccta
     1381 tgagggcaat ctccagtttc gtcagcaaat caatagtaag ttagaatacc aaaaagcttt
     1441 tgagattgct tgcaagatag agggctatcc aaggcaaacc tctgtccatg cggctggtgt
     1501 tgtaattagt gaccaagatt taaccaacta cattcctcta aagtatggtg atgaaattcc
     1561 actgactcag tatgatgctc atggagttga ggctagcgga cttttgaaga tggactttct
     1621 gggactacga aatttgacct ttgtccagaa gatgcaagag ttgcttgctg aaacagaagg
     1681 tattcatctg aaaattgaag aaatcgattt agaagacaaa gaaacgttag ctttatttgc
     1741 ctctggtaat acaaaaggta tctttcaatt tgagcaacca ggtgccattc gtctgcttaa
     1801 gcgtgtgcaa ccagtctgtt ttgaagatgt cgtcgcgact acttctctaa atcgaccggg
     1861 tgctagtgac tatatcaata attttgtggc aagaaagcat gggcaggaag aagtgactgt
     1921 tctggatcca gtactggagg atattttggc tccaacctac ggcataatgc tctatcagga
     1981 gcaggttatg caggttgccc agcgatttgc tggatttagt cttgggaagg ccgatatttt
     2041 gcgtcgagct atgggtaaaa aggatgcttc tgctatgcat gagatgaggg cttcctttat
     2101 tcaaggctcc atagaagcag gccatactgc ggaaaaagca gagcaggttt ttgatgttct
     2161 ggagaagttt gcaggctatg gttttaacag gtcacacgcc tacgcctact cagccttggc
     2221 cttccagttg gcttatttta aaacacatta tccagccata ttttatcaga ttatgttgaa
     2281 ttctgctaac agtgattatg taacagatgc cttagaagca ggttttgaag tagccccatt
     2341 gtccatcaac acgattccct atcacgataa aattgccaac aaggccatct atctaggttt
     2401 gaaatccatt aaaggagtca gtaatgattt agctctctgg attattgaac atagacctta
     2461 ttctaacatt gaagatttta tagctaaatt acctgagaat tatctgaaac ttcctctgct
     2521 agaacctttg gtaaaagttg gtcttttcga ttcatttgaa aaaaatcgtc aaaaagtatt
     2581 taataactta gctaatctat ttgaatttgt gaaagagttg ggaagtttgt ttggagatgc
     2641 tatttatagt tggcaggaat cggaagattg gacggaacaa gaaaaatttt atatggaaca
     2701 agagctttta gggataggtg tcagcaaaca tccactacaa gctattgcaa gtaaggctat
     2761 ttacccgatt accccaatcg gaaatttgtc agaaaatagc tatgctatta ttttggttga
     2821 agttcagaaa ataaaagtga ttcgtaccaa aaagggtgaa aatatggcct tcttacaggc
     2881 agatgatagt aagaaaaaat tggatgtcac tctcttttca gacttatatc gtcaggttgg
     2941 acaggaaata aaagagggag ccttctacta tgtaaaagga aaaatacaat cacgtgatgg
     3001 ccgtctgcaa atgattgcac aagaaataag agaagcagtt gctgaacgct tttggataca
     3061 ggtgaaaaat catgaatcgg atcaagaaat ttcacgtatt ttagaacaat ttaaaggccc
     3121 aatcccagtc atcatccggt atgaagagga acagaaaacc atcgtttctc cccatcattt
     3181 tgtagctaaa tccaatgaat tagaggagaa attgaatgaa atcgttatga aaacgattta
     3241 tcgctaaaaa tacggaaaat agaagaattt taaaatcaaa tgtgatataa tcaagaagaa
     3301 tgttaaaaga aaaaggagca taaaccaata tgaaacgtat tgctgttttg actagtggcg
     3361 gagacgcacc tggtatgaac gctgctatcc gtgcagttgt tcgtcaagca atttcagaag
     3421 gaatggaagt gtttggtatc tatgacggat atgctggtat ggttgccggt gaaattcatc
     3481 ccctagatgc agcttcagta ggagacatca tttctcgtgg tggtactttt cttcactcag
     3541 ctcgttatcc agagttcgct caacttgaag ggcaacttaa agggattgag caattgaaaa
     3601 aacacggaat tgaaggtgta gttgttatcg gtggtgacgg atcttaccac ggcgctatgc
     3661 gtttgactga acatggcttc ccagctattg gtcttccagg tacaatcgat aacgatatcg
     3721 ttggtactga ctttacaatc ggttttgaca cagcggttac tactgccatg gacgctattg
     3781 ataagattcg tgatacatca tcaagtcacc gtcgtacttt tgtaatcgaa gttatgggac
     3841 gtaacgctgg tgatatcgct ctttgggctg gtattgcaac tggtgctgat gaaatcatca
     3901 tccctgaagc agactccaag atggaagata tcgtagcaag catcaaagct ggttatgaat
     3961 gtggtaaaaa acacaatatc atcgtcttag ctgaaggtgt gatgtcagcg gctgaatttg
     4021 gtcaaaaact taaagaagct ggagatacaa gcgaccttcg tgtaacagaa cttggacata
     4081 ttcaacgtgg tggttctcca actgcgcgtg accgtgtttt ggcgtcacgt atgggtgcac
     4141 atgctgttaa acttcttaaa gaaggtatcg gtggtgttgc ggttggtatt cgtaacgaaa
     4201 aaatggttga aaatccaatt cttggtactg cagaagaagg ggcattgttt agccttactg
     4261 cagaaggtaa gattgtggtt aacaacccac acaaagccga tattgagcta tctagcttga
     4321 ataagagctt gtcataattt acaatttagt taataagacc aaaaaggtca tatatataaa
     4381 ggagtcacaa aaatcatgaa caaacgtgta aaaatcgttg caactttggg tcctgcggta
     4441 gaaatccgtg gtggtaaaaa attcggtgag gacggatact ggggtgaaaa acttgatgtt
     4501 gaagcttcag ctaaaaacat tgctaaattg attgaagctg gtgctaacac attccgattc
     4561 aacttctcac acggcgacca ccaagaacaa ggtgagcgta tggcaactgt taaacttgcg
     4621 gaaaaaattg caggtaaaaa agttggtttc cttcttgata caaaaggacc tgaaatccgt
     4681 acagaattgt tcgaaggtga agctaaagaa tattcataca aaactggtga aaaaattcgt
     4741 gttgcaacta aacaaggaat caaatcaact cgtgaagtga ttgcgttgaa cgttgctggt
     4801 gctcttgata tctatgatga tgttgaagtt ggtcgtcaag ttttggttga cgatggtaaa
     4861 cttggtcttc gtgtggttgc taaagatgat gaaactcgtg aatttgaagt tgaagttgaa
     4921 aacgatggta tcatcgctaa acaaaaaggt gtgaacatcc ctaacactaa aattcctttc
     4981 ccagctcttg ctgaacgcga taacgacgat atccgtttcg gtcttgaaca aggtatcaac
     5041 ttcatcgcaa tttcattcgt acgtactgca aaagatgtga acgaagttcg tgcaatctgt
     5101 gaagaaactg gaaacggaca tgttcaattg ttcgctaaaa tcgaaaacca acaaggtatc
     5161 gataacttag acgaaatcat cgaagcagct gatggtatta tgattgctcg tggtgatatg
     5221 ggtatcgaag taccgttcga aatggttcca gtttatcaaa aaatgattat caagaaagtc
     5281 aatgctgcag gtaaagttgt tatcactgca acaaacatgc ttgaaacaat gactgaaaaa
     5341 ccacgtgcaa ctcgttcaga agtatcagac gtattcaacg ctgttatcga cggaactgac
     5401 gctacaatgc tgtcaggcga gtctgcaaac ggtaaatacc cactcgagtc agtaactaca
     5461 atggctacaa tcgacaagaa cgctcaagct cttcttaatg aatacggacg tcttgattca
     5521 gattcatttg agcgtaactc taagacagaa gtaatggctt ctgctgttaa agatgctact
     5581 agctcaatgg atatcaaatt ggttgtaact cttactaaga caggtcatac tgcacgtttg
     5641 atttctaaat accgtccaaa tgctgacatc ttagcattga catttgacga attgacagaa
     5701 cgtggcttga tgttgaactg gggtgttatc ccaatgttga cagatgctcc atcttcaact
     5761 gacgatatgt tcgaaatcgc tgaacgtaaa gcggtagaag caggtctcgt tgagtcaggc
     5821 gatgatatcg ttatcgttgc tggtgtgcca gtaggagaag ctgttcgcac aaacacaatg
     5881 cgtatccgca cagtacgtta agaaaaatat aaaaacctat catatccagc tttctagtct
     5941 gtatgatggg ctcttttttt gtccaggggg gcaaaaaggg ggcaaaactt tcataatgga
     6001 ttgatactct tcgaaaatca aattcaaacc acgtcagcgt cgccttaccg tactcaagta
     6061 cagcttgcgg ctagcttcct agtttgctct ttgattttca ttgagtatga aataagatat
     6121 gcacaaattg attaggaaat tcaaatgaat ttctacaaat gttttagcaa tcgtaatgta
     6181 cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta aaacctccaa
     6241 agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg ttttagcgtt
     6301 tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa ggagtgtgtg
     6361 cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag tatttgcctt
     6421 ttgcaaagtg atgttaaatg cctttctcta aatttacata tcactattgt ttaacaaaat
     6481 ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt tttcaaagtt
     6541 tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt tttaattctc
     6601 cctatatagc ctgacaactt tcccgatggt acgaatatgg ttgctttcgt ctaggtggat
     6661 gtcggggtat ttgggattga gtttttttaa ggtagccttg gcggagtttc ttgacatagt
     6721 tagcgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg gtattcttga
     6781 taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgatg acataagcga
     6841 ttgggtcgta gtcgtctggg ataatggaaa ctccatatct aaatcgttgt cctgcatcga
     6901 gcggctacct gcagagataa actatctaac acgagagtaa gtagtctgtc tgtagtcgtc
     6961 cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct ctcggcatag
     7021 gtcagaactt taccttgtct ggatggtgcc cgttggtcgt agatagattg gatatcgcta
     7081 ggagaatcct tttgaactgg agaaaagagg gcatcaatca agctactgaa tactttaact
     7141 aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt tccaatggtg
     7201 tttttactta taccaatctt agtacccaat tcttattgag ttcaaccatt actagtctat
     7261 attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa catttctagg
     7321 aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctac tatatttttc
     7381 gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct atttttgtaa
     7441 gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc gtaaaaaatt
     7501 tgttgacaga gcacgaaacg cctactataa ttaaatcaag cttaaggaaa taacaaaaaa
     7561 acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat atctgtaaag
     7621 caatagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag aaatcaagaa
     7681 aattagccac attaggaatc tgttcagctt tgtttttagg cttggctgct tgtcaacaac
     7741 aacatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa gttccatgga
     7801 aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa tctctcttat
     7861 cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat gactataata
     7921 ctattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac accgaatacg
     7981 atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt gggaccaact
     8041 gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag cttgaaaaga
     8101 atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc tttgattcac
     8161 aagataagga agagtttgat attctatttt cgagagttcc aactgaggca actacagatg
     8221 tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc aatgaaaaag
     8281 ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg tttgtaggcc
     8341 acgttggggt cttagtacct actgatgacg gtttcttatt tgtagagaaa ttgactttcg
     8401 aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag tatttaggca
     8461 ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg gataatgata
     8521 agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt ttatttctat
     8581 ttttgatgag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc aaaaatgaaa
     8641 catttattgg ctatatccaa agatacgata ttgatgggaa tggctatcaa tcattaccgt
     8701 gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacta ctttgaacaa gagttacttc
     8761 aacccattgg atccgacgga gtaagttgct ttcgtggata ccaaaaacag ccgcaatttc
     8821 ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt cttctaggct
     8881 taatttaggt tttcgtcccc cttttgtgtg tttaagttga taagcagttt ttaatacagc
     8941 taatatctct tcaaaagtgg tgcgctgaac accaacaaga catttaaatc gtgcatcagt
     9001 tagttgttta cttgcttcat cattcataga ac
//
LOCUS       DAVMCN010000068         8915 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVMCN010000068 DAVMCN010000000
VERSION     DAVMCN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8915
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.069"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            72..6503
                     /locus_tag="VYP85_001820"
     CDS             72..6503
                     /locus_tag="VYP85_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1882288.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQDPDLFAFNNQGVHAESTSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVS
                     REHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEG
                     KSLFNIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAY
                     DDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEI
                     KATKYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKET
                     KSEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQ
                     SVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6795..7141)
                     /locus_tag="VYP85_001821"
                     /pseudo
     CDS             complement(6795..7141)
                     /locus_tag="VYP85_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7298..7584)
                     /locus_tag="VYP85_001822"
                     /pseudo
     CDS             complement(7298..7584)
                     /locus_tag="VYP85_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7612..7839
                     /locus_tag="VYP85_001823"
     CDS             7612..7839
                     /locus_tag="VYP85_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1882289.1"
                     /translation="MRERLLTQLLLHADETSYRVLESDSQLTYYWTFLSGKVENQAIT
                     LYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            7915..8467
                     /locus_tag="VYP85_001824"
                     /pseudo
     CDS             7915..8467
                     /locus_tag="VYP85_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3319 a         1326 c         1749 g         2521 t
ORIGIN      
        1 tttataacaa aggctagcaa agttaaagtt tattatctat tggaagttaa ataaatatgt
       61 aaggaattaa aatgaaaaaa agtacagtat tgtcattaac cacagctgca gttattttag
      121 cagcctatgc ccctaatgag gtagtcttag cagacacatc tagctctgaa gatgctttaa
      181 acatctctga taaagaaaaa gtagtattag ataaggaaac agaaaataaa gagaaacatg
      241 aagatattca taatgctata gaaacttcac aggattttaa agagaagaaa acagcagtca
      301 ttgagggaaa agaagttgtt agtaaaaatc ctgtgacaga caataacact agcaatgaag
      361 aagcaagaat caaagaagat tccaatcaat cccaaggaga tcatacggac tcatttgtga
      421 ataaaaacac agaaaatccc aaaaaagaag ataaagttgt ctatattgct gaatttaaag
      481 ataaagaatc tggagaaaaa gcaatcaagc aactatccag tcttaagaat acaaaagttt
      541 tatatactta tgatagaatt tttaacggta gtgccataga aacaactcca gataacttgg
      601 acaaaattaa acaaatagaa ggtatttcat cggttgaaag ggcacaaaaa gtccaaccca
      661 tgatgaatca tgccagaaag gaaattggag ttgaggaagc tattgattac ctaaagtcta
      721 tcaatgctcc gtttgggaaa aattttgatg gtagaggtat ggtcatttca aatatcgata
      781 ctggaacaga ttatagacat aaggctatga gaatcgatga tgatgccaaa gcctcaatga
      841 gatttaaaaa agaagactta aaaggaactg ataaaaatta ttggttgagt gataaaatcc
      901 ctcatgcgtt caattattat aatggtggca aaatcactgt agaaaaatat gatgatggaa
      961 gagattattt tgacccacat gggatgcata ttgcagggat tcttgctgga aatgatactg
     1021 aacaagatat caaaaacttt aacggcatag atggaattgc acctaatgca caaattttct
     1081 cttacaaaat gtattctgac gcaggatctg ggtttgcggg tgatgaaaca atgtttcatg
     1141 ctattgaaga ttctatcaaa cacaacgttg atgttgtttc ggtatcatct ggttttacag
     1201 gaacaggtct tgtaggtgag aaatattggc aagctattcg ggcattaaga aaagcaggca
     1261 ttccaatggt tgtcgctacg ggtaactatg cgacttctgc ttcaagttct tcatgggatt
     1321 tagtagcaaa taatcatctg aaaatgaccg acactggaaa tgtaacacga actgcagcac
     1381 atgaagatgc gatagcggtc gcttctgcta aaaatcaaac agttgagttt gataaggtta
     1441 acattggagg acaaagtttt aaatacagaa atataggggc ctttttcgat aagaataaaa
     1501 tcacaacaaa tgaagatgga acaaaagctc ctagtaaatt aaaatttgta tatataggca
     1561 aggggcaaga ccaagatttg ataggtttgg atcttagggg caaaattgca gtaatggata
     1621 gaatttatac aaaggattta aaaaatgctt ttaaaaaagc tatggataag ggtgcacgcg
     1681 ccattatggt tgtaaatact gtaaattact acaatagaga taattggaca gagcttccag
     1741 ctatgggata tgaagcggat gaaggtacta aaagtcaagt gttttcaatt tcaggagatg
     1801 atggtgtaaa gctatggaac atgattaatc ctgataaaaa aactgaagtc aaaagaaata
     1861 ataaagaaga ttttaaagat aaattggagc aatactatcc aattgatatg gaaagtttta
     1921 attccaacaa accgaatgta ggtgacgaaa aagagattga ctttaagttt gcacctgaca
     1981 cagacaaaga actctataaa gaagatatca tcgttccagc aggatccaca tcttgggggc
     2041 caagaataga tttactttta aaacccgatg tttcagcacc tggtaaaaat attaaatcca
     2101 cgcttaatgt tattaatggc aaatcaactt atggctatat gtccggaact agtatggcga
     2161 ctccaatcgt agcagcttct actgttttga ttcgaccaaa attgaaggaa atgcttgaaa
     2221 aacccgtatt aaaaaatctt aaaggtgatg ataaaataga ccttacaagt cttacaaaaa
     2281 tagccctaca aaatactgca agacctatga tggatgcaac ttcttggaaa gaaaaaagtc
     2341 aatactttgc atcacctaga cagcaggggg cggggctaat taatgtggcc aacgctttga
     2401 gaaatgaagt tgtagcgact ttcaaaaaca cggattctaa aggtttggta aattcatatg
     2461 gttccatttc tcttaaagaa ataaaaggtg ataaaaaata ctttacaatt aagcttcaca
     2521 atacatccaa caggccttta acctttaaag tttcagcatc agcggtaact acagattctc
     2581 taactgacag actaaaactg gatgaaacat ataaagatga aaaatctcca gatggtaagc
     2641 aaattgttcc agaaattcat ccagaaaaag tcaaaggggc aaatattaca tttgagcatg
     2701 acactttcac tataggggca aattctagct ttgatttaaa tgcggttata aatgttgggg
     2761 aggctaaaaa taaaaataaa tttgtagaat catttattca ttttgagtca gtagaagaaa
     2821 tggaagcatt aagctccaat ggcaagaaaa ccgacttcca accatcttta tcaatgcccc
     2881 taatgggatt tgctgggaat tggaaccacg aaccaatcct tgataaatgg gcttgggaag
     2941 aaggatcaaa atcaaaaaca atggaaggtt atgatgatga cggtaaacca aaaattccag
     3001 gaaccttaaa taaggggatt ggtggagaac atggtataga taaatttaat ccagcaggag
     3061 ttatccaaaa tagaaaagat aaaaatacaa catctctaga tcaagatcca gacttatttg
     3121 cctttaacaa ccaaggtgtt catgcagaat ccactagtgg ttctaagatt gctaacattt
     3181 atcctttaga ttcaaatgga aatcctcaag atgctcaact agaaagagga ctaactccat
     3241 ctccacttgt tctaagaagt gcagaagaag gactaatttc aattgtaaac accaacaaag
     3301 aaggagaaaa ccaaaaagac cttaaagttg tatcaagaga gcacttcata agaggaattc
     3361 taaattctaa gggaaatgac gctaagggta tcaaatcatc caaactaaaa gtttggggtg
     3421 acttgaaatg ggatggactc atctataacc caagaggtag agaagaaaat gccccagaaa
     3481 gtaaggataa ccaagatcca gctactaaga tacgaggaca atttgaaccg attgcggaag
     3541 gtcaatattt ctataaattt aaatatagat taactaaaga ttacccatgg caggtttcct
     3601 atattcctgt aaaaattgat aacacagccc ctaagattgt ttcggttgat ttttcaaatc
     3661 ctgaaaaaat taagctaatc acaaaggata cttatcacaa ggtaaaagat caatacaaga
     3721 atgaaacttt atttgctaga gatcaaaaag aacatcctga aaaatttgat gagattgcaa
     3781 atgaggtgtg gtatgcagga gctgctcttg ttaatgaaga tggagaggtt gagaaaaatc
     3841 ttgaagtaac ttatgcaggt gagggtcaag gaagaaatag gaagcttgat aaagatggga
     3901 atactatcta tgaaattagc ggagcaggag atctaagagg aaaaatcatc gaagtaatcg
     3961 ccctagatgg agcaagcaac tttaccaaaa tccataggat taaatttgct aatcaagctg
     4021 atgaaaaagg gatgatttcc tattatctag tagatcctga tcaggattca tctaaatacc
     4081 aaaagcttgg cgaaattcct gaatctaaat ttaagaattt aaaaaatgtt aaagatgata
     4141 gcctaaacaa agagacagct gaggtggaaa ataacctttt agtagataat cagtctatcg
     4201 aaggaaaatc tctctttaat attcataaaa ctatttcaac aattagagac tttgaaaata
     4261 aagacctaaa gaaactcatt aaaaagaaat ataagcaaga agacgacttt gtaaatggtg
     4321 gaacaagaac agtagagcgt gattataaat acgatgataa aggaaatata atagcctacg
     4381 atgatgggac tgatctagaa tatgaaactg agaaacttga cgaaatcaaa tcaaaaattt
     4441 atggtgttct aagtccgtct aaagatggac actttgaaat tcttggaaag ataagcaatg
     4501 tttctaaaaa tgccaaggta tattatggga ataactataa atctatagaa atcaaagcga
     4561 ccaagtatga tttccactca aaaacgatga catttgatct atacgctaat attaatgata
     4621 ttgtggatgg attagctttt gcaggagata tgagattatt tgttaaagat aatgatcaga
     4681 aaaaagctga aattaaaatt agaatgcctg aaaaaattaa ggaaactaaa tcagaatatc
     4741 cctatgtatc aagttatggg aatgtcatag aattagggga aggagatctt tcaaaaaaca
     4801 aaccagacaa tttaactaaa atggaatctg gtaaaatcta ttctgattca gaaaaacaac
     4861 aatatctgtt aaaggataat atcattctaa gaaaaggcta tgcactaaaa gtgactacct
     4921 ataatcctgg aaaaacggat atgttagaag gaaatggagt ctatagcaag gaagatatag
     4981 caaaaataca aaaggccaat cctaatctaa gagccctttc agaaacaaca atttatgctg
     5041 atagtagaaa tgttgaagat ggaagaagta cccaatctgt attaatgtcg gctttggacg
     5101 gctttaacat tataaggtat caagtgttta catttaaaat gaacgataaa ggggaagcta
     5161 tcgataaaga cggaaatctt gtgacagatt cttctaaact tgtattattt ggtaaggatg
     5221 ataaagaata cactggagag gataagtcca atgtagaagc tataaaagaa gatggctcca
     5281 tgttatttat tgataccaaa ccagtaaacc tttcaatgga taagaactac tttaatccat
     5341 ctaaatctaa taaaatttat gtacgaaatc cagaatttta tttaagaggt aagatttctg
     5401 ataagggtgg ttttaactgg gaattgagag ttaatgaatc ggttgtagat aattatttaa
     5461 tctacggaga tttacacatt gataacacta gagattttaa tattaagttg aatgttaaag
     5521 acggtgacat catggactgg ggaatgaaag actataaagc aaacggattt ccagataagg
     5581 taacagatat ggatggaaat gtttatcttc aaactggcta tagcgatttg aatgctaaag
     5641 cagttggagt ccactatcag tttttatatg ataatgttaa acccgaagta aacattgatc
     5701 ctaagggaaa tactagtatc gaatatgctg atggaaaatc tgtagtcttt aacatcaatg
     5761 ataaaagaaa taatggattc gatggtgaga ttcaagaaca acatatttat gtaaatggaa
     5821 aagaatatac atcatttgat gatattaaac aaataacaga caagacacta aacattaaga
     5881 ttgttgtaaa agattttgca agaaatacaa ccgtaaaaga attcatttta aataaagata
     5941 cgggagaggt aagtgaatta aaacctcata gggtaactgt gaccattcaa aatggaaaag
     6001 aaatgagttc aacgatagtg tcggaagaag attttatttt acctgtctat aagggtgaat
     6061 tagaaaaagg ataccaattt gatggttggg aaatttctgg tttcgaaggt aaaaaagacg
     6121 ctggctatgt tattaatcta tcaaaagata cctttataaa acctgtattc aagaaaatag
     6181 aggagaaaaa ggaggaagaa aataaaccta cttttgatgt atcgaaaaag aaagataacc
     6241 cacaagtaaa ccatagtcaa ttaaatgaaa gtcacagaaa agaggattta caaagagaag
     6301 atcattcaca aaaatctgat tcaactaagg atgttacagc tacagttctt gataaaaaca
     6361 atatcagtag taaatcaact actaacaatc ctaataagtt gccaaaaact ggaacagcaa
     6421 gcggagccca gacactatta gctgccggaa taatgtttat agtaggaatt tttcttggat
     6481 tgaagaaaaa aaatcaagat taagataaaa gctatagaaa aaaatggttt atgtactgag
     6541 attagatagt gaggtgatga catagttttg tgaaaacagc catttataac tcaattattt
     6601 agtttacttc actattgata ctatttggag ttattaatgg acttagttta gataactaat
     6661 gaattgattg aaagggttag tattgacaat attggtcata ttgattagaa aatagagtct
     6721 atcaaaattt aaaggctaat agaggtgatg agacaatttc ggctctttgt caactgtagt
     6781 gggttgaaga aaagctaagc tcgagaaagg acaaattttg tcctttcttt tttgatattc
     6841 agagcgatga aaatccgttt tttgaagttt tcaaagtttc gaaaaccaaa ggcattgcgc
     6901 ttgataagtt tgatgagatt attggtcgtt tccagtttgg cattagaata gtgtagttga
     6961 agggcattga caatcttctc tttatctttg aggaaggttt tagaggatga acctgattca
     7021 gattgtcctc aatgagtccg aaaaatttgt caggctcctt attctgaaag tgaaaaagca
     7081 agagttgata gagattatag tggtgtttca agtcttctga atagctcaaa agtttatcta
     7141 tagtagattg aaactagaat agtacacatc tgcttctaaa acattgttag aaatcgattt
     7201 gactgtcctg atcgatttgt cctggtctta tttcatttca ttataaattc atcagaaagt
     7261 cgtgatttct attgaaatga ggactttctt tttacactca tctgctttca aaaagcattc
     7321 tagtccatct ccgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat
     7381 cttccaaagt tcgaaaggct ttattcttaa atccacgttt acgaatctct ttccacactt
     7441 gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaaacca atattagtcg
     7501 gaatctttaa ggtacttgat ttatgccata tagcattgtc cataagagta aaagataatc
     7561 atctggataa gcttatgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag
     7621 agactattga ctcagctctt acttcatgca gatgaaacct cttatcgggt cttagaaagt
     7681 gatagtcagc tgacctacta ttggactttt ttgtcaggga aagttgagaa tcaagcaatc
     7741 acgctgtacc accatgatca gcgtcggagt ggtttagtag tacaagaatt cctaggagat
     7801 tattctggct atgtgcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag
     7861 ttctgcctat gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac
     7921 tgcgagccgc tagaagctta tcgtcaactg gcagaagctg aacttgttgg atgttgggcg
     7981 catgtgagaa ggaaattttt tgaagcgacc cccaagcaag cagataaatc atccttagga
     8041 gctaaaggtt tagcctattg tgaccagtta tttgccttgg aaagagactg ggaggctttg
     8101 ccagctgatg aacgactaca gaaacgtcaa gaagagctcc aacccctaat ggaagatttc
     8161 tttgcttggt gccggcgtca gtcagtttta gcaggttcaa aactaggaag ggcaattgaa
     8221 tacagcctca agtataaaga aacctttaag actattttga aagacggaca tctggtcctt
     8281 tccaataatc tagctgaacg cgccattaaa tcattggtta tgggacggag taaaagagtc
     8341 cagtggactc ttttagccta agctaaattt taaaaagcga gggtggttat tttctcaaag
     8401 ttttgaagga gctaaagcaa gagctattat tatgagtttg ttggaaacag ctaaacgtca
     8461 tcaattatag tgcgttgaat ctataacagt acgcatcgac tgctaaaata tttctataaa
     8521 tcaattttcc tttcctaatc gatttgtgca tatcttattt caatccatta taaatagcga
     8581 gaaatatcta tcctatcttc tagaatgtct tctaaacgtg gaaactctcg taaacaaaga
     8641 ggttttagag gcttatttac tatggactaa agttgtacaa gaaaagtgca aataagaaat
     8701 ctccagatta ggaactatcc gtgagttcac taatctggag atttttcaat agacttcgtt
     8761 attggacggt tacgatatga tcactgactt cgtcagttct atctacaacc taaaaacagt
     8821 gttttgaaca acctgcggct agcttcctag tttgctcttt gattttcatt gaatattaga
     8881 acagcaaaaa tgcttgaagt atttgtttgt gtttt
//
LOCUS       DAVMCN010000069         8879 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVMCN010000069 DAVMCN010000000
VERSION     DAVMCN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.070"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            129..284
                     /locus_tag="VYP85_001825"
                     /pseudo
     CDS             129..284
                     /locus_tag="VYP85_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            484..3759
                     /gene="rexB"
                     /locus_tag="VYP85_001826"
     CDS             484..3759
                     /gene="rexB"
                     /locus_tag="VYP85_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1882290.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3756..7406
                     /gene="addA"
                     /locus_tag="VYP85_001827"
     CDS             3756..7406
                     /gene="addA"
                     /locus_tag="VYP85_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1882291.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVECILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7576..8754
                     /locus_tag="VYP85_001828"
     CDS             7576..8754
                     /locus_tag="VYP85_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882292.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLMFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KNQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLGRLVI
                     "
BASE COUNT         2759 a         1845 c         1882 g         2393 t
ORIGIN      
        1 actatattag attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta
       61 gaaatatttt agcatccacg atgtactatt atagtttcaa tttactatag ttcaatcatt
      121 ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat
      181 tagagtccga tgttgatggc gataaatcag acaatctacc cgtcgacatt aagatactgg
      241 gacaacacat tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagtcttgtt
      301 accgaggctt ttttattatg tgattttcag tagccagact tattctatct aatacaagta
      361 aagctaagta tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt
      421 aacagattta cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct
      481 gagatgaaat tactttatac tgatattcga acttctttga cagaaattct aacaagagag
      541 gcagaagagc tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct
      601 tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc aggcttcttt ttctattacc
      661 gtcacgcgct ttgctcaaat ggctcgttat ctggtcctga atgatttacc agttaaaact
      721 actcttgatg atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc
      781 aaggacttgc gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt
      841 gagctttacc atgagatgac caaatctcag atgagttttt tggacttgga gaatttaaca
      901 gatgaggata agaggacgga tttactcttg atttttgaga aagtaacagc ctatcttaat
      961 caaggtcagt tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac
     1021 aaggtaagta gtgattttaa tcaaatcacc ttggtcattg acggctttac tcgtttttct
     1081 gctgaggaag agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg
     1141 gcttatgcta gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc
     1201 agcgtaaaat ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct
     1261 caaactcatg agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat
     1321 gacttttcag aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg
     1381 tcttgtttga cgcaaaagga ggagttggag ctagtagccc gtagcattcg tcagaaatta
     1441 catgagaact cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct
     1501 taccagttat ctctcaaaac catttttgac cagtatcaga ttccttttta tcttggtaga
     1561 agcgaagcca tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa
     1621 cgttaccgtt ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac
     1681 ctcagtcagt ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc
     1741 ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt
     1801 ttgaatgtcc tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa
     1861 caaaaggctg aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc
     1921 aagcagttac aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa
     1981 gtttggaagg ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag
     2041 gttagtctgg aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt
     2101 accattccag caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg
     2161 actgctgact ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa
     2221 aacaccagtc ttctgacaga tgaagaaagg caaaatctaa accaagcgac cgaagaaggc
     2281 gttcaattac tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc
     2341 ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt
     2401 gaaagtaagg aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag
     2461 aagaggatga atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg
     2521 tctagtctgg ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact
     2581 tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag atctgcaagg tctggaaaat
     2641 ccagctatcc caaccagtcc aagcagcaag accttagcca aggacacctt gcaagctctc
     2701 tatcctgcca aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat
     2761 gaatacagtt atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct
     2821 gatgcccgta gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt acagttgcct
     2881 aatgaagatt cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc
     2941 gaatttgaag ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt
     3001 gatgttgcac ggacgactgg acatattctc cgacacaatc cagccatcga aaccatcaaa
     3061 gaagaagcaa attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt
     3121 gtctttgtac gaggcaaggt ggaccggatt gaccgtttga aagctaatgg agcgatagga
     3181 gtagtagact acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc
     3241 aattctcagt taccaaccta tcttgctgcc ctaaaaagag aaggggagca gaactttttc
     3301 ggcgccatgt acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg
     3361 gcaggagcag tggtagaagc cagcaaatct atgaaatacc aagggctctt cttggaaaaa
     3421 gaaagcagtt atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag
     3481 gaatttcagc tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt
     3541 ttagcaggcc ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac
     3601 gtccagcaac atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt
     3661 ttcctagaaa agttggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa
     3721 gcttggtttg aaaaaataag agaggagtta aatcgatgaa gcttattccc tttttaagtg
     3781 aggaggagat tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa
     3841 ctgccgaaca aatcgaagct atctacactt ctggtcagaa tatcctggtc tcagcatcgg
     3901 ctggttctgg aaagaccttt gtcatggtag agtgcattct ggaccaattg gcgcgtggtg
     3961 tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag
     4021 aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac
     4081 aacacttggg tcgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt
     4141 tcacacaaaa attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta
     4201 ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg
     4261 aagcgcatta ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg
     4321 ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta taaaatctat gacttcctcc
     4381 aatccaccag taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag
     4441 ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt
     4501 tggaaagctt tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct
     4561 atttagaaaa tgttcagtta attctggatg aaattggctc cctaaatcag gagttcgata
     4621 gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc
     4681 gagctctgac taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg
     4741 aagagagaaa gacccagttt actaaactag gacaattatc agaccagata gcgattctcg
     4801 actatcaaga acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca
     4861 tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg
     4921 ctgatatcag ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt
     4981 atcaggagcg cttccatgaa gtcatggtcg atgagtatca ggatatcaac catattcaag
     5041 aacggatgct ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc
     5101 aatccatcta tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct
     5161 atgcgcaaaa tcctcaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt
     5221 cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg
     5281 aaatcaacta tgataacatg caccagcttg tttttgccaa taccaaactg actcccaatc
     5341 cagacaacaa ggccgaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga
     5401 gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag atccttaaac
     5461 ttcatcagga aaaaggtgtt gcctttaagg aaattgccct tctgacctct agtcgtaatc
     5521 gtaatgacca aattctactt gccctgtctg agtacgggat tcctgtcaaa actgacggag
     5581 agcaaaacaa ttatctccaa tccctagaag tgcaagtcat gctagacacc cttcgtgtca
     5641 ttcacaatcc cctgcaagac tacgccttgg ttgcccttat gaagtctcca atgtttggtt
     5701 ttgatgagga tgagctagca cgtttgtccc ttcagaaagc agaggataaa gcccacgaaa
     5761 atctctatga gaaactagtc aatgcacaaa aaaaggcaag tagtcaaaaa ggcttgattc
     5821 acacagctct agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt
     5881 atgccaaacc ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt
     5941 atgactatgt tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag
     6001 cactgcgtgc tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta
     6061 tgattgacca agtcttagaa gcccagcacg atttggcaag cgtggccgtc gcaccgccaa
     6121 aagatgcagt agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct
     6181 ttatcctcaa tatggatcaa gatttcaaca aacaagactc tatgtcagaa gtcattctca
     6241 gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag
     6301 accactatcc taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag
     6361 aggaattaca gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc
     6421 gggctgagaa aaagctctat cttgtcggca agggttctcg tgaaaagctg gaatccaagg
     6481 aatacccagc agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt
     6541 tccaagattg gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt
     6601 atcgttttat tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga
     6661 gtcctctcca agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc
     6721 tggaaatgct gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc
     6781 ctagtgttca aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag
     6841 gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag
     6901 atttttcaac caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca
     6961 tgcagagaat tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac
     7021 aagttcaaac tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct
     7081 ttgacacagc actcggtcag gaaatttttg ctaataccga ccatctctat cgcgagcaac
     7141 ctttctccat gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc
     7201 ttgatggcta tctgctttac gaaaacaaaa ttgttttgtt cgactacaag acagaccgct
     7261 atgatgaacc aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg
     7321 ctttatcacg agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag
     7381 acgaggttca agttgtaaaa gtataactta tactcttcga aaatctcttc aaaccacgtc
     7441 agcttcgcct tgctgtatat atggttactg acttcgtcag ttctatccac aacctcaaaa
     7501 cagtgttttg agctgactgc ggctagcttt ctagtttgct ctttgatttt tattgagtat
     7561 tagaaaggag acctcatgac acttccagtt agaaaatccc tgcacgatgc agttttacag
     7621 gcttcgaaag cggatacttg ggaacaagct accaaggaat ggaatgaagt ttccttgatg
     7681 tttaacggta tcggccgtag caattgtgtc tgtggaaatg ccatcaaata cgcttatgaa
     7741 ctctttaacg gtgtcacagg ccaacgcctc tttccaattg gtagcgactg tgttcgtcat
     7801 tttcatcgat tgtcccttga ccagcaattg gaagaggaag aaaaactgct cagaaaggtt
     7861 gaaaatctaa ccagaaaagc tcagaaaaag gaaaaaatca aggtcaataa aagtgacttt
     7921 gacgagcgac ttctaaaatg gctctgggaa aaaggtgttt tcaaacccaa tcgtggcaat
     7981 caatttgcgc ctgagagaga ctaccagctt ttcctagaag tctttcaggg aggaagttgg
     8041 accaaggcgg aaccaaagaa aaaggctcgg atggaagaag tccttgaaaa gtgtatcaaa
     8101 ccatttttac ttgggaaatc ggatgaccaa ctctaccttg tcaagctagg caaggagaaa
     8161 attgactacg aacaagaact ccgtatccag gcagagaaag aacgcaagaa gagggataaa
     8221 atcgccaagc aatatgcaga taatctggtt ctagccatgg gacccgcaga gcgtgcttat
     8281 caagattact ttggctttac agagaccctg actcaagaag aacgcaagtg ggaaaaaatt
     8341 ctttttggta aaaatagagc agaacgggct atcaaggcca aacaatacca aaaagagctg
     8401 gaaaaaaacc aacgaattgc cagtcaggat ccaattgaaa gaaaacagaa gcagacttgg
     8461 ctcctcaatt cctattttcg agagcttcct gaagaaaaag ctcgattttc taggctctta
     8521 ttagaatatc gaaaaagtgg tgaagtaccc ttttcaactg aatacctgtc agatcatctc
     8581 atcgactttt tctataaaat gaaagccttt gaatttgaaa tcgcaccaga acaagtccga
     8641 gattttctaa aaaaaagcct gcaggaagac catcgctcat cagcacaagg aagctggata
     8701 gaaggaattc tcctcaactg cctcaaacca tttttaggac gattagtgat atgagtaaca
     8761 cctaccgtgt aaatttcatg gtaggtgtta ttgtacccca aaataatata aaacaaagta
     8821 tgaaagcgca tctcaatttt aagacttttt tgtaaattaa gagtataatt aaggtatac
//
LOCUS       DAVMCN010000070         8811 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVMCN010000070 DAVMCN010000000
VERSION     DAVMCN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8811
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.071"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            181..1968
                     /locus_tag="VYP85_001829"
     CDS             181..1968
                     /locus_tag="VYP85_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1882293.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEYIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            1965..2441
                     /locus_tag="VYP85_001830"
     CDS             1965..2441
                     /locus_tag="VYP85_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1882294.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            2469..3374
                     /locus_tag="VYP85_001831"
     CDS             2469..3374
                     /locus_tag="VYP85_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1882295.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            3361..4176
                     /locus_tag="VYP85_001832"
     CDS             3361..4176
                     /locus_tag="VYP85_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1882296.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            4183..4587
                     /locus_tag="VYP85_001833"
     CDS             4183..4587
                     /locus_tag="VYP85_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1882297.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            4886..6052
                     /locus_tag="VYP85_001834"
     CDS             4886..6052
                     /locus_tag="VYP85_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1882298.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            6168..7205
                     /locus_tag="VYP85_001835"
     CDS             6168..7205
                     /locus_tag="VYP85_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1882299.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            7322..8535
                     /locus_tag="VYP85_001836"
                     /pseudo
     CDS             7322..8535
                     /locus_tag="VYP85_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
BASE COUNT         2491 a         1659 c         2000 g         2661 t
ORIGIN      
        1 tccgaattta aagagcgttt gaaatgggtc taaaaatgtt tgaaactaat tgaatgtgtg
       61 tataatagta aaaatgcagt aaatatcccg acaatttcta ttgacaattc aaacagattg
      121 gtttataatt aatataacaa caaatgaaag cgcaaacttt cgcggtcgga aggtagtttt
      181 atgacacgat ttgagatacg agatgatttc tatctcgatg gaaaatcatt taagatttta
      241 tctggtgcca ttcattattt tagggttcct ccagaggatt ggtatcattc gctctataac
      301 ttgaaggctc ttggttttaa tacggtagag acttatgttg cttggaattt acacgagcct
      361 cgtgaaggtg agtttcattt tgaaggtgat ctggatttag agaaatttct ccaaatagcg
      421 caggatttgg gtctctacgc aattgtgcgt ccgtctccat ttatctgtgc ggaatgggaa
      481 ttcggtggct taccagcttg gctcttgacc aagaacatgc gaattcgctc atccgaccca
      541 gcatatatcg aggcagttgg tcgctactat gatcagttat tgccaagact ggtgcctcgt
      601 ttgttggaca atggtggcaa tattctcatg atgcaggttg aaaatgagta tggttcttac
      661 ggagaagata aggcttacct gagagcgatt cgacagctaa tggaagagtg tggcgtaacc
      721 tgtcccctct ttacatcaga tggtccatgg cgagctactc tgaaagctgg aaccttaatt
      781 gaagaggacc tctttgtaac aggaaacttt ggttctaagg caccttacaa cttttcgcag
      841 atgcaggaat tctttgatga acatggtaag aaatggccac tcatgtgtat ggagttctgg
      901 gatggttggt tcaatcgctg gaaagaaccg attatcacac gggatcctaa ggaattggca
      961 gatgcagttc gagaggtttt ggaacaaggc tctatcaatc tttacatgtt ccacggtggt
     1021 acaaactttg gtttcatgaa tggttgctca gctcgaggaa ctttggacct gccacaagtt
     1081 acgtcttatg attacgatgc ccttctggat gaagaaggaa atccaactgc taaatatctt
     1141 gcagtcaaga agatgatggc aacacatttt tcagagtatc cgcagttgga accactctac
     1201 aaagagagta tggagttgga tgctattcca ctagttgaaa aagtttcttt gtttgaaacc
     1261 ttagatagct tgtcaagtcc tgtagaaagt ctctatcctc aaaagatgga ggagctggga
     1321 caaagttatg gctacctact ttatcgaaca gaaacaaact gggatgcaga agaagaaaga
     1381 cttcgtatca ttgatggtcg agatagggcc cagctgtatg tcgatggtca gtgggttaaa
     1441 actcaatatc agacagagat tggggaatat attttttatc aaggtaaaaa gaaagggcta
     1501 tctaggttag atatcttgat agaaaatatg gggcgtgtca actatgggca taagttctta
     1561 gcggatacgc aacgtaaggg aattcggaca ggggtctgta aggatctgca tttcttacta
     1621 aactggaaac actatccact cccactagac aatcctgaga aaattgattt ttcaaaagga
     1681 tggactcaag gacaaccagc cttttacgct tatgacttta cagtcgaaga gccaaaagat
     1741 acttacctag acttgtctga gtttggtaag ggggttgcct ttgtcaatgg gcagaatcta
     1801 ggacgttttt ggaacgttgg cccaactctc tcactttata tccctcatag ctatctcaag
     1861 gaaggtgcca accgcatcat tatctttgaa acagaaggtc aatataaaga agagattcat
     1921 ttaactcgta aacctacact aaaacatata aagggggaaa acttatgaca attgtaggat
     1981 gccgtattga tggacgtttg atccacggac aagtagccaa tctttgggct ggaaaactaa
     2041 atgtttcacg cattatggtt gtagacgacg aagttgtcaa caacgatatt gaaaagagtg
     2101 gtttgaaact tgcgacacca ccaggtgtga aattgagtat tttgccagtt gagaaagctg
     2161 cagccaatat tcttgctggc aaatacgata gccaacgtct ctttatcgtg gctcgtaaac
     2221 cagaccgctt ccttggtttg gtagaagcag gtgtaccact tgaaaccctt aatgttggga
     2281 atatgtctca aacaccagaa actcgttcta ttacacgttc tatcaacgta gtagacaagg
     2341 atgtggaaga cttccacaaa ctggcagaaa aaggtgttaa acttactgct cagatggttc
     2401 caaatgatcc aatttcagac tttttgagct tattaaaata ggaaaaaaat ttttaggagg
     2461 tcattgttat gatacaatgg tggcaaattt tacttctcac tttgtactca gcttatcaaa
     2521 tctgtgatga gttgacgatc gtttcatctg caggttcccc tgtatttgct ggtttcatta
     2581 ctggtttaat catgggagat gtgactactg gtttacttat cggtggtaac ttgcaactgt
     2641 tcgttcttgg ggttggtacc ttcggtggtg cttctcgtat cgacgcaact tctggtgcgg
     2701 ttcttgcgac agccttctct gtttcacaag gaattgatgc accgcttgcc attactacaa
     2761 tcgctgtacc agtagcagct ctcttgactt acttcgacgt tcttggtcgt atgactacta
     2821 ccttcttcgc tcaccgtgtg gatgctgcaa tcgaacgctt tgactataaa ggtattgaac
     2881 gcaactactt gcttggtgcg attccgtggg ctctatctcg tgcccttcca gtcttctttg
     2941 cccttgcttt tggtggtgcc tttgtacaat cagtagtaga cttcgttgaa gcctacaaat
     3001 gggttgcaga tggcttgaca cttgcaggac gtatgcttcc aggtcttgga tttgcaatct
     3061 tgcttcgtta ccttccagtt aaacgtaacc ttcactacct tgctatggga tttggtttga
     3121 cagctatgtt gactgttctt tactcatatg taacaggtct tggtggcgct gttgctggta
     3181 tcgtaggtac tcttcctgct gaagttgctg aaaaaattgg tttcgtgaac aacttcaaag
     3241 gtttgtctat gattggtatt tctatcgtag gtattttcct tgcagtgctt cacttcaaaa
     3301 atagccaaaa agtagctgta gcagcacctt ctacaccatc agaaagtggg gaaatcgaag
     3361 atgacgaatt ctaattacaa acttacaaaa gaagatttta atcaaatcaa caaacgtagc
     3421 ttgtttactt tccaattagg ttggaactac gaacgtatgc aagcttctgg ttacctttac
     3481 atgatcttgc ctcagttgcg taaaatgtat ggtgatggaa ctcctgaatt gaaagaaatg
     3541 atgaaagttc atactcaatt cttcaatact tcaccattct tccataccat tatcgctggt
     3601 tttgaccttg ccatggaaga aaaagatggt gtaggttcaa aagacgccgt taacggtatc
     3661 aagacaggtt tgatgggacc attcgctcct cttggggata caatctttgg ttcacttgta
     3721 cctgctatca tggggtcagt cgcagcaact atggctatcg ctggccaacc ttgggggatc
     3781 ttcctttgga ttgcagttgc agtagcgtat gacatcttcc gttggaaaca gttggaattt
     3841 gcttacaaag aaggggttaa ccttatcaac aacatgcaaa gtaccttgac agctttgatt
     3901 gacgctgcat ctgtacttgg tgtcttcatg atgggtgctc ttgtagcaac agtgattaac
     3961 tttgaaattt cttacaagtt gccaatcggt gaaaagatga ttgatttcca agacatcttg
     4021 aaccaaatct tcccacgttt gcttccagca atctttactg cctttatctt ctggttgctt
     4081 ggtaagaaag gtatgaactc tactaaagct atcggtatta ttatcgtact tgctttggct
     4141 ctttctgccc ttggtcactt tgcacttgga atgtaattcc ttatgactaa atcattaatt
     4201 ttggtgagcc atggtcgctt ctgtgaggag cttagaggta gcacagaaat gattatgggc
     4261 ccacaagaca acatttacac agtagctctt cttccagaag atggcccaga agaatttact
     4321 gctaaatttg aagctgttat tgaaggattg gatgatttcc tagtctttgc ggatcttctc
     4381 ggtgggacac cttgtaatgt ggtgagtcgc ttgatcatgg aaggtcgtga tattgacctt
     4441 tacgcaggga tgaatcttcc aatggtgatt gaatttatca atgcgagcct tacaggcgca
     4501 gatgcggact acaagagccg tgctgcagaa agcattgtga aagttaatga cctgttagcg
     4561 ggcttcgatg atgacgaaga tgaataatac tcttcgaaaa tctcttcaaa ctacgtcaac
     4621 gtcgccttgc cgtaggtata tgttactgac ttcgtcagtc ttatccggca acctcaaaac
     4681 ggtgttttga gctgacttcg tcagtcttat ccggcaacct caaagcagtg ctttgagcag
     4741 cctgcggcta gtttcctaca gattttagtt ggaactcgat tcaattcatg tgacaacgtg
     4801 aaaatcgtta gagcatttta tatagaatat acatgggaat gtagcttact cccattccca
     4861 tatttaatag aaaaagagga actcaatgct acattataca aaagaagact tgctcgaatt
     4921 gggtgcagaa atcactacgc gtgaaatcta ccaacagcct gatgtatgga gagaagcttt
     4981 tgaattttat caagcaaaac gtgaagaaat tgcagccttc ctacaagaaa tcgctgataa
     5041 acatgactat attaaggtta tcttgacagg tgctgggact tctgcttatg tgggagatac
     5101 cttgctacct tattttaagg aagtctatga cgaacgcaaa tggaatttca atgctattgc
     5161 gacaacagat atcgttgcca atccagcaac ctatttgaaa aaagatgtgg caactgtcct
     5221 tgtgtctttt gctcgtagtg ggaattcgcc tgaaagtttg gcgactgttg atttggccaa
     5281 atccttggtg gatgagcttt atcaagtgac gattacttgt gcagcagatg gtaaattggc
     5341 tcttcaagct cacggtgatg atcgtaatct cttgctcttg caaccagctg tctctaatga
     5401 tgctggattt gccatgactt ctagctttac gtctatgatg ttgacaactc tcttggtctt
     5461 tgatcctaca gaatttgctg ttaagtctga acgttttgaa gttgtatcta gtcttgcccg
     5521 taaagtttta gacaaggcag aagatgtcaa agagctcgtt gatttagact ttaaccgtgt
     5581 catctatcta ggcgctggtc ctttctttgg acttgctcat gaagctcagc tcaagatttt
     5641 ggaattaact gctggtcaag ttgcgaccat gtatgaaagc ccagttggct tccgtcacgg
     5701 tccaaaatct cttatcaacg acaatacagt tgttttggtc tttggtacaa cgacagacta
     5761 cactcgtaag tacgacttgg acttggttcg tgaagttgct ggtgaccaga ttgctcgtcg
     5821 tgttgtgctt ttgagtgatc aagcttttgg tcttgaaaat gtcaaagaag tggcccttgg
     5881 ttgtggcggt gtcttgaatg atatttaccg tgtcttccct tacatcgttt atgcccaact
     5941 ctttgcttta ttgacttcac tcaaggtaga aaataaacca gatacaccgt ctcctacagg
     6001 tacagtaaac cgtgtagtac aaggtgtcat aattcacgaa tatcaaaagt aagacagtgt
     6061 ttatgaattc ttgacaagag gatttgtaaa ttatcagata aaccatagat tgtcagtacg
     6121 ctttctatgg tttgtttgct tgagagaaat agtaaaagga gaacagaatg aaagcataca
     6181 cagagcgtgt atttggaaat gttgagggtg aggatgtctt ggcctatcga tttgagacag
     6241 acggtggcta ccaacttgag gttatgactt atggtgcgac tatcttgcgc tatgtcgcac
     6301 ctgacaaggc tggaaatttt gccaatgtta tcttgggatt tgatgacttt gatagttatg
     6361 taggcaatag tcccaagcat ggagcaagtg taggtcctgt agcgggtcgt attgcaggtg
     6421 cgacctttga gctcaatggt aagacctatg accttgaggt taataatgct agcaactgta
     6481 atcacagtgg ttcaactggt tgggattcca gcttgtttga agttgaagaa gtaagcgatc
     6541 atggcttgac tctctacaca gagcgtacag atgggacagg agggttccct ggaaatctca
     6601 agatttggat cagttatcac ttggaagaaa ctggtgccta tgaaatcagc tacaaggtaa
     6661 cgaccgatca ggatacgctg gtcaatccaa ccaaccacag ctatttcaac ttgtctggtg
     6721 atttcacgca gacgattgac cgtcatgtct tccaactaaa cacagagggc atttactcaa
     6781 tcgctcctga cggtgttcct gccaaaactc cagaagccaa ccgtgatgtg gtcaaacacg
     6841 tctacaatgg taccttgttg aaggatatct ttgcagaaga agatgagcaa atccagctgg
     6901 catcaggttt ggatcatcca tttgcccttc ctgcaggcca tgacaatgct ggattccttt
     6961 atgaccaaaa ttcaggtcgc ttcctgcttt tcaagacaga agctccttgc tttgtggtct
     7021 acacagcaaa ctttgtggat gaaagtgtca tcataggagg tcagccaatg ctacagcaca
     7081 atgggattgc tcttgaagcg caagctttac cagatgccat tcacagtgac cttaaaggcc
     7141 aagtcattct taaagctggt caaaccttca ccagtaagac acgttatgaa cttgttgtga
     7201 agtaaaagag tcattgcgcc tacttttggg agctaggaat aggtacgcag agacaaatag
     7261 taggaaaata tgatataact aagcgttgaa agctatctgt taatataata ttcaaactac
     7321 aataaggagt aagaaagaaa cgaagaaaat tgtatttgct agtgccttgg ctttgacctt
     7381 ggctggagca gttttgacaa atgatgtttt tgcgaacgac agacttgtgg caacacaaac
     7441 tactgatggt aaaaatgaaa atgtattgac ctcagaggtg ctaaaacctt ctagtggcaa
     7501 tgttttggtt ggaatcaaag gagaatttgt ggctcctcat caacaatcta ttttggatgc
     7561 catcaatgct atctgtaaag aagcggctga cgaaggtttg gtagataagt atgtccctat
     7621 caaatggtca actgacctag aaaaggcagc ttttgccaga gctacagaag catctataac
     7681 catggatcat acccgtcttt ctagcaaaga tctttggagt gcctttccaa cttctaatag
     7741 tataatggga gaaaatttgg catggaatca tgacggtttt ctaaaagcta ttgaacaatg
     7801 gcgtgctgaa aaagcagatt atgtggagaa aaaaatagtg gttcagacaa cgggaaatct
     7861 ggtcactatg agtcgctaat taaccctaaa tttacacaca tggggatggc agcttttaaa
     7921 aatcctaaca atcaatacaa agctattaca attgctcaaa ctctaggtga tgatgcttct
     7981 tcagaggaat tggctggtag atatggttct gctgttcagt gtacagaagt gactgcctca
     8041 aacctttcaa cagttaaaac taaagctacg gttgtagaaa aaccactgaa agattttaga
     8101 gcgtctacgt ctgatcagtc tggttgggtg gaatctaatg gtaaatggta tttctatgag
     8161 tctggtgatg tgaagacagg ttgggtgaaa acagatggta aatggtacta tttgaatgac
     8221 ttaggtgtca tgcagactgg atttgtaaaa ttttctggta gctggtatta cttgagcaat
     8281 tcaggtgcta tgtttacagg ctggggaaca gatggtagca gatggttcta ctttgacggc
     8341 tcaggagcta tgaagacagg ctggtacaag gaaaatggca cttggtatta ccttgacgaa
     8401 gcaggtatca tgaagacagg ttggtttaaa gtcggaccac actggtacta tgcctacggt
     8461 tcaggagctt tggctgtgag cacaacaaca ccagatggtt accgtgtaaa tggtaatggt
     8521 gaatgggtaa actaggctca ggccataggt aaagcattca tcttacttag caaaaagaat
     8581 gaacgataag aaagaggttg atggcgaaca ttggcctctt ttgatttata aagattggat
     8641 tcttgtcgcc tcaatttcag acttttctat tgtaagctaa tattttatag cccattaaaa
     8701 gcataagcgg taatctaatt taaaaaatgc tgtaattagt ctgaagtcca cacttacttg
     8761 ttgagatgtt atctctgttt tttatcgtta taatttactg tattttttat a
//
LOCUS       DAVMCN010000071         8635 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVMCN010000071 DAVMCN010000000
VERSION     DAVMCN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.072"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..991
                     /locus_tag="VYP85_001837"
     CDS             <1..991
                     /locus_tag="VYP85_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1882300.1"
                     /translation="NGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQKVIE
                     ELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNAIVEY
                     FGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSGVVYV
                     SNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDLKVIY
                     GLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISIIGFDN
                     IPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1596..1673
                     /locus_tag="VYP85_001838"
                     /pseudo
     CDS             1596..1673
                     /locus_tag="VYP85_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            1885..2040
                     /locus_tag="VYP85_001839"
     CDS             1885..2040
                     /locus_tag="VYP85_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882301.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            2175..3536
                     /gene="trpE"
                     /locus_tag="VYP85_001840"
     CDS             2175..3536
                     /gene="trpE"
                     /locus_tag="VYP85_001840"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1882302.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKIILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDAFYSERSQEALEKSLNQV
                     LEELRIPVPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSDYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3533..4099
                     /locus_tag="VYP85_001841"
     CDS             3533..4099
                     /locus_tag="VYP85_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1882303.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            4110..5114
                     /gene="trpD"
                     /locus_tag="VYP85_001842"
     CDS             4110..5114
                     /gene="trpD"
                     /locus_tag="VYP85_001842"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1882304.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNLGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLEMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5111..5878
                     /gene="trpC"
                     /locus_tag="VYP85_001843"
     CDS             5111..5878
                     /gene="trpC"
                     /locus_tag="VYP85_001843"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1882305.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            5865..6464
                     /locus_tag="VYP85_001844"
     CDS             5865..6464
                     /locus_tag="VYP85_001844"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1882306.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKDGISGTK"
     gene            6442..7665
                     /gene="trpB"
                     /locus_tag="VYP85_001845"
     CDS             6442..7665
                     /gene="trpB"
                     /locus_tag="VYP85_001845"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1882307.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7658..8434
                     /locus_tag="VYP85_001846"
     CDS             7658..8434
                     /locus_tag="VYP85_001846"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1882308.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIKTEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8406..8507)
                     /locus_tag="VYP85_001847"
                     /pseudo
     CDS             complement(8406..8507)
                     /locus_tag="VYP85_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
BASE COUNT         2563 a         1601 c         2071 g         2400 t
ORIGIN      
        1 aaatgggaaa aaggtaacta tttatgatat tgcacgttta tcaggttttt ctccaaaaac
       61 agtttcacga gttattaatg gtggagtaaa tgttaaagaa gaaacttatc aagcgattca
      121 aaaagttata gaggaattgt cgtatattcc aaatgcgtat gcaaaaaatt taactaaaaa
      181 agaagctata aatatattga tttctgtaaa aaaaatcgac tcttttcctt taatttggtt
      241 tcatacgctg ttagataaag tgttacggac gtgtaaagaa tttggtgtta atgctatagt
      301 tgagtacttt ggagaggagg atacaattag taattcaatt atatcaagca caggtagcct
      361 agtagatggt gttattgttt tttatgaaag tgtagatgat atcagaattc agtatttaaa
      421 gaagaaccat atgccttttc ttgttttcgg tgaatctcaa acgtctggag tagtctatgt
      481 atctaataat aattttcaag ctacttatga tatgatgaaa gctgtaactg aagaaaaatt
      541 taaaaatatg tggttgctta tgggaggaga atctcatgtt aataaggatc gtgaaagagg
      601 tgtgcgttct tttctgaatg ataaaaatta ctttatggat ttaaaagtca tttatggctt
      661 atctacaatt gattcagttt attcttatgc aatgcagcac ttgactaccc aaaattatcc
      721 ggacattatt tttgtttcag gagatgaaaa ggttcagggc ttgattcgtg cgtgctatga
      781 gaaaggaatt cttattccag atgatatttc tattattgga tttgataata ttcctatttc
      841 tcagtattat actccagctt tgtctacaat tgctcccaat tatgttaaat tggctaaaga
      901 aatgatagaa ggtgttttag caattattaa aggggaaagt gtcacatctg ttgaagtttc
      961 tcctaaattt gttaggagac agagtttcta gtattgttta attcttgaaa atcctagtgg
     1021 aaaagatgga gtgttctaaa ataagttctg tttagcctcc attcagtttc tattgagttg
     1081 gatccaattt ctaacaagtg ggacatgttc atgttcgatc taaggaagat atggtcacat
     1141 tcgaatgata tcaaaaaaat cgtaaaaaag tcttgacaaa gaaaaaacaa agtattaaaa
     1201 taagttcaac aaatcagaaa agtaactatt tttgatcttc agggagcctg tggtgattgt
     1261 gaataggtgg ttggaagtag tgaaagtggg ctgattttga aaatgaattt gaaacaatga
     1321 aaattcggtg cgcacacctt acagtgcagc ttgttgttaa acaaggcaga gatgtaaagg
     1381 gatagtccct ttataattga ggtggcaccg cgttaccaac gccctcacac ggaagtatat
     1441 tctgtgtgtg ggcttttttc tatccgtcgt ttggtttatc ttttattagg gccttaagtc
     1501 gctttgatga acttgagttc tatctacagc tccttgccta ctactaaaag caaacaaaaa
     1561 ggctggacta atacgaaaaa agctagtaat actcaatgaa aatcaaagag caaactagga
     1621 aactagccgc aggctgctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca
     1681 gctcaaaaca ctgttttgag gttgcagata gaactgacga agtcagtaac catacctacg
     1741 gaaaggcgac gttgacgcgg tttgaagaga ttttcgaaga gtataaaggt gtaccgagat
     1801 gaacatctct tcatcaatgt ctctggtcgt ggaggcaagg acctagctgc gattgcagac
     1861 tacctagaag ctaaaaaata atagatggaa aaattacagt tctttctctc acagagagct
     1921 tgtggttgct ggaaacaagc agagaaagct gtaaagttgg gttcatctga aacgagagaa
     1981 gaaaacatca ttctcaaggg agtgcccttt atcgcacagc ctgttacagg agatatctga
     2041 gacaggaatg agagatagga gaaatcctat aattgaggtg gcaccgcgaa tttcgtcctc
     2101 acgcaagtta ttttgcgtgg ggatttttca tacagtcgct acgaactaga attagaactg
     2161 aaagggaaat tacaatggaa cgaatcattc atggagatgt cttatcacca atcttggctt
     2221 atatgcgctt aaaggggcaa cacaagatta tcttagagag tattccgaga gacaaggaaa
     2281 cagctcgttt ttctatccta gcctataatc ctgtttttga gattaagttt gaaaatggag
     2341 ttctttatca aaatggtcaa gtgattgatc gggatccctt ggatttcctt tatgaagtga
     2401 ttcataagag tcagcaccat tcagagctac cttttggtgg tggagccatt ggttttgtgg
     2461 gttacgatat gatttcgctt tatgaagaaa ttggtcaaat ccctgaggat acaattggga
     2521 cgccagacat gcatttcttt gtctatgaga gctatatagt ctttgaccac aagaaggaga
     2581 agatacatgt catagaggat gcattttata gtgagcgcag tcaagaggcc ttggaaaaat
     2641 ccttgaacca agtgcttgag gaattacgca ttcctgttcc aaatgaattt gaagacttgg
     2701 atctatctcc gttagacttc aaaccgcata tcgctccaca taagtttgag ggaatggtag
     2761 aaacagctcg tgacttgatt cgtaacggag atatgttcca atgtgtactc agccagcgtt
     2821 tctcagcaga agttactgga aatccatttg acttctacag aaatctccgc gtgactaatc
     2881 cttctgatta cctttatttc tatgattttg gggattatca aatcatcgga gctagtccag
     2941 aaagtttggt ttctgtcaaa aatggcatcg tgacaaccaa tccgattgca gggacgcgac
     3001 caagaggggc tacggatgaa gaagacaaga ccttggcgac tgacctcctc tctgatgaga
     3061 aggaaacagc agaacatcga atgttggtag acttggggcg taacgatatt ggccgcatct
     3121 ctgaaacggc cagtgtccaa gttactaagt atatgaaggt ggagctcttc cgctacgtca
     3181 tgcatttgac cagtgtggtc aaggggcgtt tgcttgcaga actcactgct atggatgcct
     3241 tgaaagcaac gcttcctgct ggaaccgttt ctggagcacc aaaaattcga gcgatgagac
     3301 gcatctatga actggaaacg gaaaaacggg gcgtatatgc aggagcaatc ggctacttgt
     3361 ctgcgacggg tgatatggat ttggccattg ccatccgaac catgattctc aaaaatcaaa
     3421 gagcctatgt gcaggctggg gcagggattg tctacgactc tatcgcccaa aacgaatacc
     3481 aagaaaccat taacaaagca aaatctatga ctagaattgg agaactaaga ccatgatttt
     3541 attgattgac aactatgatt cttttaccta taacttggcc caatacattg ggaattttgc
     3601 agaagttcag gttttgagaa atgatgattc caagctgtat gaagaagctg aaaaagcaga
     3661 tggtctggtc ttttctcctg gtcctggttg gccagttgat gctggaaaga tggaagacat
     3721 gattcgtgat tttgcaggca agaagccgat tctagggatt tgtttgggcc accaagccat
     3781 tgcagaagtc tttggtggta agctaggttt ggctccaaaa gtcatgcatg ggaaacagag
     3841 caatatcaac tttgaagcgc catctgtttt gtatcaaggt attgaggatg gccgtgcggt
     3901 catgcgttat cacagtattt tgattgagga aatgccagaa gactttgaag tgacagctcg
     3961 ttcgactgat gaccaagcca tcatggggat tcaacataaa aacctaccga tttatggctt
     4021 ccagtaccat ccagagagca ttggaacgcc agacggcttg tcttctattc ggaattttat
     4081 cgaggaggtt gtaaagtgag gaaactagga tgaaagagat tattgaaaaa ctagcaaaat
     4141 ttgaaaattt atcaggtgtg gaaatgacgg atgtcattga gcgtatcgta actgggcgtg
     4201 taactgaagc gcagattgct tctctcctct tagctcttaa gatgaagggg gaaacacctg
     4261 aagaacgcac agccattgcc caagtcatga gaggacatgc ccagcatatt ccaactgaga
     4321 ttcatgatgc catggataac tgtggtacag gtggggacaa gtctttcagt tttaatattt
     4381 ccacaactgc agcctttgtc ttggctggtg gcggtattca catggccaag catggtaacc
     4441 gctcgatttc ttctaaatct ggttccgcag atgtcctcga agccttggga atcaatcttg
     4501 atctcaaacc agctgaacta ggtaaggtct ttgataaaac tggaatcgtc tttctcttcg
     4561 ctaaaaatat gcacccagct atgaaataca tcatgccagc tcgtttggaa ttgggaattc
     4621 caacgattat gaacttgact ggtccactga ttcatccaat ggctttagaa acacagcttc
     4681 ttggaattag tcgtccagaa ctcctagaaa gtacagctca ggttttgaaa aatctgggtc
     4741 gcaaacgtgc catcgtggtt gctggaccag aagggttgga tgaagctggc ttgaacggaa
     4801 caaccaagat tgcacttctt gaaaatggcg aaatcagctt gtcaagcttt actccagagg
     4861 atttggaaat ggaaggctat gctatggaag atattcgtgg tgggaatgct caggaaaatg
     4921 cagaaatttt gcttagcgtt ctgaaaaacg aagcaagtcc attcttggaa acgacagtct
     4981 tgaatgctgg tcttggtttc tatgctaatg gtaagattga tagcatcaag gaaggagttg
     5041 ccttggcccg tcaagtgatt gctagaggca aggcccttga aaaactcaga ctgttacagg
     5101 agtaccaaaa atgagtcagg aatttttagc acgaatctta gagcagaagg cgcgtgaggt
     5161 ggagcagatg aagctggagc aaatccagcc tctgcgccag acctatcgct tggcagaatt
     5221 tttgaagaat catcaggacc gcttgcaggt aatcgctgag gtcaagaaag ctagccctag
     5281 tttgggagat atcaatctcg atgtggatat tgtgcaacag gcccagactt atgaagaaaa
     5341 cggagcagtg atgatttcgg tgttgacaga tgaggttttc tttaaagggc atttggatta
     5401 tctacgggaa atttccagtc aggtagagat tccgacgctc aacaaagact ttatcataga
     5461 tgaaaagcaa atcatccgcg ctcgcaatgc aggtgcgaca gttatcttgc ttattgtggc
     5521 agccttgtcc gaagaacgcc tcaaggaact gtatgactac gcgacagagc ttggtctgga
     5581 agtcttagtg gagactcaca atctagctga actagaggta gcccacagac ttggtgctga
     5641 gattatcggg gtcaacaacc gcaacttgac tacctttgag gtcgacttgc agaccagtgt
     5701 agatttagcc ccttactttg aggaaggtcg ctattacatt tctgaatctg ccattttcac
     5761 agggcaggat gcggaacgac tagccccata ctttaacgga attttggtag ggacagctct
     5821 tatgcaggca gaaaatgtgg cccagagaat caaggagttg cagattgaca aaggttaaaa
     5881 tttgtggact atcgaccaaa gaagcggtgg aaacagccgt ttcagcagga gccgactata
     5941 tcggttttgt ctttgcacct agtaaaagac aggtgacttt agaagaggca gctgagttgg
     6001 caaagcttat tcctgcagat gtgaaaaagg ttggagtatt tgtttcacca agtcgggtag
     6061 aactgctgga agcgattgac aaagttggct tggacttggt tcaagttcac ggtcaggtgg
     6121 cagatgattt atttgagaat ttgccttgtg ccagtattca ggctgtgcag gtagatggaa
     6181 atgggcatgt ccccaattct caggcagatt atctactctt tgatgcccct gtggcaggaa
     6241 gtggccagtc ctttgattgg ggtcaactgg atacgactgg actagcacag cccttcttta
     6301 tcgcaggtgg ccttaatgaa gataatgtag taaaagcaat tcaacatttt actccctatg
     6361 cagtagatgt atcgagtgga gtggagacag atggacaaaa agatcatgaa aagattagaa
     6421 gatttataga gagggtaaag gatggcatat caggaaccaa ataaagatgg attttacgga
     6481 aaattcggcg gacgttttgt cccagaaaca ttgatgacag cagttttgga gttggagaag
     6541 gcctaccgtg aaagtcaggc agacccaagt ttccaagagg aattaaacca acttttgcgc
     6601 cagtatgtgg gacgtgaaac tcccctttac tacgcaaaaa atttgaccca gcatatcggc
     6661 ggagccaaga tttatctcaa acgggaagac cttaaccata caggagccca caagattaac
     6721 aatgccttag gacaagtttg gcttgccaaa cgcatgggta aaaagaaaat tatcgcagaa
     6781 acgggtgctg gtcagcacgg tgtggcaact gcaactgctg cggccctctt taacatggaa
     6841 tgtaccatct acatgggtga ggaagatgtc aaacgccaag ccctcaatgt cttccgtatg
     6901 gagcttttgg gagctaaggt cgaggccgtg acagatggtt cgcgcgtgct caaggatgcg
     6961 gtcaatgcag cccttcgttc atgggtggct aatatcgacg atacccacta tatccttggt
     7021 tctgccttgg ggcctcatcc atttccagaa atcgttcgtg acttccaaag tgtcatcggt
     7081 cgagaggcta aacaacagta ccgtgacttg acaggtcgag atctgccaga tgccctagta
     7141 gcctgtgttg gtggtggatc taatgctatt gggctcttcc atccctttgt agaagatgag
     7201 tcagtagcca tgtatggagc tgaagcggct gggcttggtg tggatacaga gcaccacgct
     7261 gctaccttga ccaagggtcg tccgggtgtt cttcacggtt ctctcatgga tgtgctccaa
     7321 gatgcccatg gtcaaattct tgaagccttc tctatctcag caggtttgga ctatcctggt
     7381 atcggtccag agcattctca ctaccacgat atcaaacgtg ccagctatgt ccctgtgaca
     7441 gacgaagaag ctttggaagg atttcaactc ttgtctcgtg tggaagggat tatcccagcc
     7501 ttggaatcta gccatgctat cgcttttgcg gtgaaattgg ccaaagaact tggaccagaa
     7561 aagtctatga ttgtatgcct atcaggtcgt ggggacaagg atgtggttca agtcaaagac
     7621 cgcttggaag cagatgcagc aaagaaggga gaagctcatg cctaagacac taacagaaaa
     7681 attaaatgct ataaaagcag ctggaaaagg aatttttgtt ccctatatca tggctggaga
     7741 ccacgagaaa ggtttggatg gactaggaga aacaatccac tttttagaag atttgggtgt
     7801 ctctgcaatt gaagtgggta ttcccttttc agaccctgtt gcagatggac ctgttatcga
     7861 agaagctggc ttgcgcagtt tagcccacgg gacctctacc caggctttag ttgaaacctt
     7921 gaaaaccatt aaaacagaga ttccactggt catcatgacc tacttcaacc ccctctttca
     7981 gtacggtgtg gagaactttg tcaaagatct ggctgataca gctgtgaagg gcttgattat
     8041 cccagacttg cctcatgaac atgccaactt tgtagaacca tttttggcag atacagatat
     8101 caccttgatt cctttagtaa gcttgaccac aggaattgag cgccagaaag agttgattga
     8161 aggggcggag ggattcgtct atgccgttgc catcaatgga gtgacaggga aatcaggcaa
     8221 ttaccgtgca gatttggaca agcacttggc gcaacttcat caagtggccg acatcccagt
     8281 cttgacaggt tttggtgtat ctagtcaagc cgatctggaa cgcttcaatg cggtgtcaga
     8341 tggtgttatc gtcggttcga aaatagtaaa agctctccac caaggagagc cgattcagga
     8401 ctttatcaaa caagcagtag cttaccaaaa ataatcaaac aagtagcaag taagaggaaa
     8461 ggaacgaaag gaagtctttc ctttttcttt tgcaggagaa aggctagttt tatagtaaat
     8521 tgaatctgga atattacact acggttccta aaatattttt agaaagtgat ttgaatttcc
     8581 caataaattt gttcagtttt taattgattt tactatagaa gatataattt tctaa
//
LOCUS       DAVMCN010000072         8170 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVMCN010000072 DAVMCN010000000
VERSION     DAVMCN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.073"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            9..1436
                     /gene="galT"
                     /locus_tag="VYP85_001848"
     CDS             9..1436
                     /gene="galT"
                     /locus_tag="VYP85_001848"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1882309.1"
                     /translation="MYNEIDKIYVKNRVLALIGEEGIDRISDENDLKQIKDYLVEIAL
                     KNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISPQEAVEEFYKLSKDSDY
                     IKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKLVKATNYPKCLLCMENE
                     GYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIFLNSQHVPMAITSKTFE
                     QLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPMEKAKFESEFCFKDFED
                     VNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEVDIIAMTEDVPHHTVTP
                     IARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKENIGLIEVMGLAILPPRL
                     KPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVNSVVQHEAGQVFARVLE
                     DAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1449..2459
                     /gene="galE"
                     /locus_tag="VYP85_001849"
     CDS             1449..2459
                     /gene="galE"
                     /locus_tag="VYP85_001849"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1882310.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2639..3298
                     /locus_tag="VYP85_001850"
     CDS             2639..3298
                     /locus_tag="VYP85_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1882311.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3323..4390
                     /locus_tag="VYP85_001851"
     CDS             3323..4390
                     /locus_tag="VYP85_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1882312.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4494..5504
                     /locus_tag="VYP85_001852"
     CDS             4494..5504
                     /locus_tag="VYP85_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882313.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDEIVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5516..7207
                     /locus_tag="VYP85_001853"
     CDS             5516..7207
                     /locus_tag="VYP85_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1882314.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7210..7920
                     /locus_tag="VYP85_001854"
     CDS             7210..7920
                     /locus_tag="VYP85_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1882315.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2743 a         1137 c         1608 g         2682 t
ORIGIN      
        1 aatacggaat gtataatgaa attgacaaaa tatatgtgaa aaatagagta ctagcgttaa
       61 taggtgagga gggaattgat cgcatttccg atgaaaatga cctgaaacaa ataaaagatt
      121 acttagtgga aatcgcctta aaaaacggta aaattaaaga tttaatcgag gaaaaggaat
      181 gtttaggagc agagttaatg aatttcatag ttcctttacc tagtcgatta aatgatattt
      241 tttggagttc atatgatata tctcctcaag aagcagttga agagttttat aagttaagta
      301 aagatagtga ttatattaaa acttctgcta ttgctaagaa tattgagttt cgagcatcaa
      361 ctaaatacgg agagctagag attacgataa atttgtcaaa acccgaaaaa gatccaaaaa
      421 caattgctgc tgaaaaatta gtaaaagcaa ctaattatcc caaatgttta ctatgtatgg
      481 aaaatgaagg atatcagggg cgaataaatt atccagcacg ttcgaatcat agaattattc
      541 ggttgaaact tggtgacgaa gtatggggat tccagtattc tccctactca tactttaatg
      601 agcatgcgat atttttgaat agtcaacatg taccaatggc tattacctct aaaacatttg
      661 aacaattatt ggagattgtt gatattttgc caggatattt tgctggttca aattctgatc
      721 ttcctatctc aggaggctcc attcttagtc ataaccacta ccagggaggg aaacatattt
      781 tcccaatgga aaaagcaaaa tttgagagtg aattttgttt taaagacttt gaggatgtta
      841 atgctggtat tgtaaaatgg ccaatgtcag taattaggtt acaaagtgaa aataaaaatc
      901 gcttgttaga tttagctact aaaattctaa ataagtggag agaatattca gatttagaag
      961 tagacatcat tgctatgact gaagatgtcc cacaccatac ggtgactcct attgctcgta
     1021 aagtggacgg gagatacgaa ttagatattg ttctaagaga taatcatact actgaacaat
     1081 acccagatgg tgttttccat cctcatcaag atgtacaaca tattaaaaag gaaaatatcg
     1141 ggttaatcga agtgatggga cttgcgatat taccacctcg tttgaaacca gagttagaag
     1201 aagttggaaa atatctttta ggagaggata atgcaattgc ggattatcat ttagaatggg
     1261 ccgaccaatt gaaagaaaaa tatcctcgca ttaataaaga agaggttaat agcgtagttc
     1321 aacacgaagc aggacaagtg tttgcgagag ttctggaaga tgcaggagtt tataagaata
     1381 caccgtctgg gcatgaagcg tttatgagat ttgttaagtc ggttggaatt aattaggagg
     1441 aaacccagat ggcaatattg gtaacaggcg gagctggtta tattggtagc cataccgtag
     1501 tagaattact aaatttagga aaggaagtta tcattgtcga caacctttcg aactctagca
     1561 aattggtgct agaccgtatt gaagcaatta caggaatacg tcccgtgttt tacgaattag
     1621 atgtttgtga taaacaagca ttgagaaagg tatttgaaca agaatcgatt gatgctgcaa
     1681 ttcattttgc aggttataaa gctgtcggag aatccgtgca aaagcctgtg atgtactaca
     1741 aaaataatat tatgagtaca ttggcacttg ttgaagtgat gtcagaattt aatgttaaaa
     1801 agattgtctt ttcttcaagt gcgactgtat atggaattaa caatcagtca cctctaattg
     1861 agacgatgca aacaagtgcg acaaatcctt atgggtatac gaaagtgatg cttgagcaaa
     1921 ttttaaaaga tgttcatgtg gcagattcag aatggagtat tgcgttgctt cgttatttca
     1981 atccaattgg tgctcatgag tctggtttga ttggggaaga tccctcagga attcctaaca
     2041 acttgatgcc ttatattgca caagtagcgg taggtaagct atcagagcta agtgtgttcg
     2101 gaaatgatta tgatacgctt gatggtactg gtgtgcgtga ttatatccat gtagtagatt
     2161 tagcaatagg acatataaaa gctttagaaa aagtatctga aaaaacagat gtttatatct
     2221 ataacctagg ctcgggagaa ggcactagtg tattacaact tgtaaataca tttgaaagtg
     2281 ttaataagat ccctattcct tataaaatag ttccaagacg ttcaggagac gttgcaactt
     2341 gttatgcaaa tgcagacaaa gcatataagg aattaaattg gaggacaaca aaatcgattg
     2401 aagacatgtg tagagataca tggaattggc aatcaaaaaa tcccaatggc tataattgat
     2461 gatactgtct atatgagtgc tgtattttga aaaaattact taacctttta atgaaatgca
     2521 tatttaatga aagataaatt taaaaaaatg tttgcaagtg cttgacaaag gaaacggttt
     2581 cattgtataa tgtaaacatg atgacaccga tgtcaaatat aaaaaagaag gtctttatat
     2641 gaaaaactta acaaaaatta agttcaaaga gaatggggaa tttaatcatt tccctgggaa
     2701 tacagttgta gcaaatcttt atactaaaca agatttgatg gaagttgttg atattattca
     2761 atcacgttat agagaattac catttatcga taagtttact ttaactccaa ggaattctat
     2821 tcacatgact gtaattgaat tgttgtgcca tgaaaatcgt gaaacggagt tttggagcag
     2881 taatcttcct ctagatacac ctttacagga aatacatgat tactttgcta aacaacttga
     2941 aatttttcca ttgttggatg aagaaattca tatgcgtata actgaaatgg gaaaacaaaa
     3001 catactagtt gaacctgcag atgaagcttc tgcaaagaga ttagaagaaa ttcgtactta
     3061 tgtctcagaa aaagcaggtg tttgtttccc taatcatgat agatatcaat tccatatttc
     3121 aattgggtat cttcggattc ctctaaccga agaggaggaa gaagagttta ctaaagtcag
     3181 agcagaatta actgaaattt tattagagaa gattccaact attactgtaa accgtattga
     3241 ctatactgta tttgaagata tgagacaatt tgttccatat cacgaaaaat ttaaataaaa
     3301 taataaaaaa ggagaactta tcatgaaaaa aatgaaagtt tggtctactg tacttgcaac
     3361 gggagttgct cttactacac ttgctgcttg ctctggaggt tcaaattcta cgactgcttc
     3421 ttcatctgaa gaaaaagctg ataaaagtca agaattagtt atctattcga actcagtctc
     3481 aaatggtcgt ggtgattggt taactgctaa agcaaaagaa gctggtttta atataaaaat
     3541 ggttgatatc gctggcgctc aattagcaga ccgtgttatt gctgagaaga ataatgcagt
     3601 tgcagatatg gtatttggaa ttggtgctgt tgactcaaat aaaattagag atcaaaaatt
     3661 actagtacag tacaagccta aatggttaga taaaattgat caatctttat cagataaaga
     3721 taattattat aatcctgtga ttgttcaacc attagtttta attggggcgc ctgatgcaaa
     3781 agaaatgcct aaagattgga ctgaattagg tagtaagtat aaaggtaaat attcaattta
     3841 tggtcttcaa ggtggtacag gacgggcaat tctagcaagt atcttagttc gttaccttga
     3901 tgaaaaagga gatttaggcg tatcagaaaa aggatgggaa gttgcaaaag aatactttgc
     3961 aaatgcctat actcttcaaa aaggtgaaag ctcagttgtt aaagcgttag ataaagaaag
     4021 cccaattcaa tacggtatga tctggggttc tggagcgtta attggacaaa aagaacaaaa
     4081 tgttgaattc aaagttatga ctcctgagat tggtgtacca tttgtaactg aacaaactat
     4141 ggttttaagc actagtaaaa aacaagcgtt agctaaagaa tttattgatt ggtttggtca
     4201 atcagaaatt caagtagaat atagtaaaaa atttggatct attcctgcaa ataaagatgc
     4261 cctaaaagag ttacctgaag atacgaaaaa atttgttgat caagtgaaac cacaaaatat
     4321 tgactgggaa gctgttggaa agcatttgga tgaatgggta gaaaaagctg aattagaata
     4381 cgtaaaataa gaaataagag ttatttttta tgtccaagtc tctctattat ttctaaattt
     4441 aaggaagaaa taaagagagg cttttggttt tagtaataga gggagttagt gagatgatta
     4501 aatttgataa tattcaaatt aaatatggtg attttgttgc aattgataat ctgaatttag
     4561 atatacatga aggggaattc tttacatttc ttgggccttc aggatgtggt aaatcaacta
     4621 ctttgagagc attggtaggt tttttagatc catcatcagg aagtattgaa gttaatggaa
     4681 cagatgtcac tcatttggaa cctgaaaagc gtggaattgg tattgtattt caatcttatg
     4741 cgctatttcc aactatgact gtttttgata atattgcatt tggtttaaaa gttaagaagg
     4801 tagctccaga tgttattaaa gctaaagtat cagcagtggc agcaaaaatt aagatctctg
     4861 atcaacagtt acagcgtaat gtatcagaat tatctggggg tcaacaacaa agggtagcat
     4921 tggctcgtgc tctggttctt gaacctaaaa ttctttgtct agatgaacca ttgtcaaacc
     4981 ttgacgcaaa attacgtgta gatttgagaa aagagttgaa aagacttcaa aaagagttag
     5041 gtattactac tttatatgtt actcatgatc aagaggaagc cttgacttta tctgatagaa
     5101 ttgcagtctt taacaatgga tacatcgaac aggtcggtac accagtagag atttatcata
     5161 attctcaaac tgaatttgta tgtgatttta ttggagatat taatgttttg accgatgaaa
     5221 tagtccacga agtattattg aaaaatacaa gcgttttctt agaggataaa aaaggataca
     5281 ttcgattaga gaaagttcga ttcaatcgtg aaactgaaca agattttatt ctaaaaggga
     5341 caattattga tgttgagttt tctggagtta caattcacta tacaataaaa gtttctgaaa
     5401 gtcagattct taatgtaaca agtattgata gtcaggctgc tattagatct gtcggagaaa
     5461 gtgtggaatt atttatcaca ccatcagacg ttctgcaatt ttaaggaggt gcagtatgcg
     5521 tcataaatta aatttaaaag attggcttat tcgtttaggg ttaatctggt tcttagtaac
     5581 atttattatt tatccaaact ttgatctagt agtgaatgta tttgtaaaag gaggagaatt
     5641 ttcccttgat gctgtacatc gtgttctaaa atctcagagg gcacttcaga gtattatgaa
     5701 cagttttaag ttagcatttt cactcattat tacagttaat gtcgtaggta ttctttgtgt
     5761 tctatttaca gagtactttg atattaaagg tgctaaaatt ttaaaattag gttatatgac
     5821 ctctttaatt tatggaggag tggttttagc gactggatat aaatttgtct atggtcctta
     5881 tggattgatt acaaaatttt tacaaaatgt tatcccttct ttagactcta actggtttat
     5941 tgggtatggt gcagtcttat tcattatgac attttcagga actgctaatc atacattgtt
     6001 tttaacaaat acaattcgaa gcgttgacta tcacactatt gaggctgctc gaaatatggg
     6061 agcaaaacca tttactgttt tccgaaaagt agtgttacca accttaattc caactctatt
     6121 tgcacttact attatggttt ttcttagtgg tttatctgca gtagcagcac ccatgattgt
     6181 tggtggtaaa gaatttcaaa ctataaatcc aatgattatt acatttgcag ggatggggaa
     6241 ttctcgtgat ttagctgccc tacttgcaat tattttaggt attgcaacta caattttgct
     6301 tactatcatg aataagatag aaaaaggtgg aaattatatt tctatctcta agactaaagc
     6361 gcctcttaaa aaacaaaaaa ttgcgtctaa gccttggaat atcattgctc acattgtagc
     6421 atatggattg ttcacagttt tcatgcttcc actaattttt atagtattat actcatttac
     6481 agatccagtt gcaattcaaa caggtaactt aacattatca aactttactt tagaaaatta
     6541 tcgcttattc tttagtaata gtgcggcatt ctctccattc ttggtcagct ttatttattc
     6601 tattattgct gcgacaacag caacaattct cgcagttgta tttgctcgtg ttgtcagaaa
     6661 acataaatct cgttttgatt tcttatttga atatggtgct ctacttcctt ggttactacc
     6721 aagtacactt ttagcagtaa gtttattatt tacttttaat cagccacaat ttcttgtctt
     6781 gaatcagatt ttggtaggta gtttggtaat tctacttatt gcatatatag ttgtaaaaat
     6841 cccattttct tatagaatgg tacgtgctat tttatttagt gttgatgatg agatggaaga
     6901 tgcagcaaga agtatgggtg cttcaccttt ttatactatg atgaaggtta tcattccatt
     6961 tattttaccg gttgttctct ctgttattgc tttaaacttt aactctttat taactgactt
     7021 cgacttatct gtattccttt accatcccct agctcaacca ttaggtatta cgattcgatc
     7081 tgcaggtgat gaaacagcaa catctaatgc acaagctctg gtatttgttt atacaattgt
     7141 tctgatgatt atttctggaa cggtattata cttcacacaa agaccggggc gtaaagtaag
     7201 gaaataatca tgacagccac tagtcttggg ttatcaaata ttgaaatagt tgtcaggatt
     7261 gttttatcag tagtcattgg tagtataatt ggtttagaga gagggagcaa atcccagcct
     7321 gcaggcatcc gaacttatag tattgtttgt ctagctgcat gtttgattat gatgacgaat
     7381 gaatacgtat cttataaatt tgggacagga gatcctacac gattaggagc tcaagttata
     7441 tcaggtgtgg gttttctagg cgctggaacg attcttatta cagataaaaa gaaaattaca
     7501 ggtctgacaa ctgcagcagg catttgggct tcggcaggaa ttggattagc tattggagta
     7561 ggtttttatg agggagctct tttagtagcc atttctgttt ggggtgtgat atccatgttc
     7621 caaccactaa aaaaatatct gcaaaatcgt tctaaaatga ttgaattgta tatagtggtt
     7681 aaatctacag aagcctataa tcgtgtattg gtttattgtg cagaaaatgg tatcagaatg
     7741 accgattcaa gaacagcgtt tggagatgtt aattctgaca gaattgaata ctttgatgtt
     7801 ccggacaaaa aaatagcgtc atttattact ctggaattat caggtagatt tgaacatctt
     7861 cgactgatgg aagaaattgc taatattgta ggtgttattt atgtcgaaga aattagctga
     7921 aatttagtaa acaaagggac agatgttttt gtccttttgc tttttagatg ttttaatcat
     7981 ctaatttttg agtagatttt tgctcagagg tttttatgaa agattataaa atcaattttg
     8041 atttaggtaa aatagaatat tttgataata attgtttgat acaagtatac aaatttattt
     8101 ctttttatga tatttgtgaa atggtgtttg cctttcattt acctcctgat gagttgataa
     8161 caaatgttat
//
LOCUS       DAVMCN010000073         8024 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVMCN010000073 DAVMCN010000000
VERSION     DAVMCN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8024
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.074"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..262
                     /locus_tag="VYP85_001855"
     CDS             <1..262
                     /locus_tag="VYP85_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1882316.1"
                     /translation="KKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDIAFYDSKDY
                     QIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            264..2486
                     /locus_tag="VYP85_001856"
     CDS             264..2486
                     /locus_tag="VYP85_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1882317.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            2526..3635
                     /locus_tag="VYP85_001857"
     CDS             2526..3635
                     /locus_tag="VYP85_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1882318.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            3792..4682
                     /locus_tag="VYP85_001858"
     CDS             3792..4682
                     /locus_tag="VYP85_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1882319.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            4707..5030
                     /locus_tag="VYP85_001859"
     CDS             4707..5030
                     /locus_tag="VYP85_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882320.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            5020..7011
                     /locus_tag="VYP85_001860"
     CDS             5020..7011
                     /locus_tag="VYP85_001860"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV1882321.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            7027..7503
                     /locus_tag="VYP85_001861"
     CDS             7027..7503
                     /locus_tag="VYP85_001861"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV1882322.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            7537..>8024
                     /locus_tag="VYP85_001862"
     CDS             7537..>8024
                     /locus_tag="VYP85_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882323.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIG"
BASE COUNT         2776 a         1127 c         1605 g         2516 t
ORIGIN      
        1 taagaaatat ttagatattc atattgttgt tgaaaatact gaaaaaatgg cagtaacttc
       61 cccagttcgt gcccagtcac gtgtaccttt tagcgaagag aaggatattg ctttttacga
      121 tagcaaagac tatcaaattg ttgaattgct tccagggaat atgttggtga cttttgaaga
      181 agatcttcac caaccaaaga ttcattgcaa tgatgaaact gttaaaaaac ttgttatcaa
      241 agttttaaac gaggaaaaat aaaatgaaaa aaaatattaa acaatatgta accttaggta
      301 ctgtagtggt attatcagca tttgttgcta actcagttgc agctcaggag actgaaactt
      361 ctgaagtatc aacaccaaag ttggtgcaac ctgttgcacc aacgactccg atttcggaag
      421 tacaacctac atcggataac tcttcggaag ttactgtaca acctcgaaca gttgaaacta
      481 ctgttaagga tccatcttct acagcggaag aaactcctgt cttagaaaaa aataatgtta
      541 ctttaacagg gggcggagaa aatgttacta aagagttaaa ggataaattt actagcggtg
      601 actttactgt agtgattaag tacaatcagt caagtgagaa aggcttacaa gctctgtttg
      661 gaatatctaa ttccaaaccc ggtcaacaaa atagttatgt agatgtgttc cttagagaca
      721 atggtgagtt ggggatggaa gcgcgtgata cttcttccaa taaaaataac ctagtatcca
      781 gacctgcttc agtttggggt aagtacaaac aagaggctgt gactaacact gttgcagtag
      841 tagcagattc agtcaaaaaa acatattctt tatacgcaaa tggtacaaaa gtagtagaaa
      901 agaaagtgga taatttccta aacatcaagg atattaaagg tattgattac tatatgcttg
      961 ggggagtgaa acgtgcagga aaaacggcgt ttggttttaa cggaacacta gaaaatatca
     1021 aattctttaa tagtgcattg gatgaagaaa ctgttaaaaa gatgacaaca aacgctgtta
     1081 ctggacattt aatttatacg gctaatgata caacaggttc taactatttc cgtattccag
     1141 ttctgtatac ttttagcaat ggtcgggtat tttcaagcat tgacgctcgt tacggtggaa
     1201 ctcatgattt cttgaataaa attaatattg ctacaagtta tagtgatgat aatggtaaga
     1261 catggactaa accaaaatta acattggcat tcgatgattt tgcgccagta ccattagaat
     1321 ggcctcgtga agttggtgga cgtgacttac aaatcagcgg tggtgcaacc tatattgact
     1381 ctgttattgt tgaaaaaaag aacaaacaag tactcatgtt tgctgatgtg atgcctgctg
     1441 gagtaagttt tagagaagca actagaaaag attcaggtta taaacaaatt gatggtaatt
     1501 attaccttaa attaaggaaa caaggtgata ctgattacaa ttatactatt cgtgagaatg
     1561 gtactgtata cgacgatcgt accaacagac caactgaatt ttcagtagat aaaaatttcg
     1621 gtattaaaca aaatggtaat tatttgacgg tagagcaata ttcggtttca tttgaaaata
     1681 ataaaaagac tgaatatcgt aatgggacta aagtccatat gaatatcttc tacaaagatg
     1741 cattgtttaa agtagtgcca acgaactata ttgcatatat ttctagcaat gatcatggcg
     1801 aatcttggtc tgcaccaact ttattacctc ctataatggg acttaatcgg aatgcgccat
     1861 atttaggtcc tggacgtgga atcattgaaa gctcaactgg acgtattctt attccgtctt
     1921 acactggtaa agagtctgcg ttcatttata gtgacgataa tggagcatct tggaaagtta
     1981 aagtagtgcc acttccttct agttggtcag cagaagcaca atttgtagaa ttgagtccag
     2041 gagtaattca agcatatatg cgtacaaata atggtaaaat tgcatattta acaagtaaag
     2101 acgcaggtac tacttggagt gcaccggaat atttgaaatt tgtttcaaat ccaagttatg
     2161 gaacacaatt atcaatcatc aattatagcc aattgattga tggtaaaaag gctgtcattt
     2221 taagtactcc aaactccaca aatggtcgta aacacggaca aatttggatt ggtctaatta
     2281 atgatgataa tacaattgat tggcgttatc atcacgacgt tgattatagt aactatggat
     2341 actcatattc aacattgaca gagttaccaa atcatgaaat tggattgatg tttgaaaaat
     2401 ttgattcatg gtctcgtaat gaacttcata tgaaaaatgt tgtaccatat ataacattta
     2461 agattgaaga tctgaaaaag aattaaagct gaaatttgaa aatatataaa aagaggataa
     2521 aaattatggt aaattacggt attgttggag ctggatattt tggagctgat ttagctcgct
     2581 caatgaacaa aattgaagat gcaaaagtgg ttgcggtatt tgacccaaat catggagaag
     2641 aagttgctca agagttggga tcagatgttt gtgcaagttt agatgaactt gtagcacgtg
     2701 aagatattga ttgtgtgatc gtagcttcac ctagctacct tcaccgtgaa ccagttgtga
     2761 aagctgctca acatggcaaa cacgtatttt gtgaaaagcc aattgcattg tcttatgaag
     2821 attgtaaagc catggttgac gcatgtaaag aaaataatgt catctttatg gctggtcaca
     2881 tcatgaactt ctttaacggt gtacaccatg ctaaagaatt gattactcaa ggtaaaatcg
     2941 gtaaagttct ttattgccat gccgctcgta caggttggga agaacaacaa ccaactgtat
     3001 catggaagaa acttcgttct caatctggag gacatttgta ccaccatatt catgaattag
     3061 attgcattca gttcatcatg ggaggacttc ctgaaaaagc gacaatggta ggaggcaatg
     3121 tatatcataa aggtgaaaac tttggtgatg aagatgatat gctcattgta aacctagaat
     3181 actctgatga tcgttatgct gttttggaat atggtaatgc tttccgttgg ggtgaacact
     3241 acgtcttgat tcaaggaact gaaggagcta tcaaacttga cttgttcaat actggaggta
     3301 ctcttcgtgt taaaggtgaa ggagaatcac acttcttagt acatgaaact caagaggaag
     3361 atgatgaccg tacagctatc tataccggtc gtggtatgga tggagcaatt gcgtacggta
     3421 aaccaggagt acgttgccca ttatggttac aaacatgtat tgataaagaa atggaatatc
     3481 tacatgacat cattaaaggt ggagaaatta cagaagaata tgaaaaactt ctcaatggtg
     3541 tagctgcttt agaatcaatc gctaccgctg atgcatgtac tttatcagtt aaagaagatc
     3601 gaaaagtaag tctttcagaa atcacaaatg cttaactatt gtaaaacaga atagtaaatt
     3661 cttgtcatta tataatttct aaagttctgt gatacaactc attgaataaa gaaatagaga
     3721 tgggactggg ataatgccca gtcccatttt ttatcaaaaa gtaatgagat caaaaatgtg
     3781 ggagtgatga aatgaagatt atagggatcg atattggcgg aacaacaatt aaggcagatt
     3841 tatacgatga ttttggaacg agtttaaatc agttcaaaga gatagaaaca attattgact
     3901 atgatttggg aacgaaccag atattaaatc aggtctgtga tttaattggt gagtatgttt
     3961 taaattattc aattgatggt gttgggattt ccactgctgg agttgttaat gctaatacag
     4021 gagaaatcat ctatgcaggc tatacaatac cagggtatat cggagtaaac tttacttccg
     4081 aaatagaaaa acgttttggg ttgtctactt ttgttgaaaa tgatgttaat tgtgctgcat
     4141 taggtgaatt gtggaaggga caagccaaag ataagaaaaa tgtagtaatg gttactattg
     4201 gaacaggtat aggaggcagt attattgtca acggacaaat tgttaacgga tttaactata
     4261 ctgctggtga agtaggttat attcctgtag gtaattcgga ttggcaaagt aaagcctcaa
     4321 caaccgcatt gattcattta tatcaaaaaa agagcttgaa aactaatcaa actggacgta
     4381 ctttcttcac tgatttaaga tctggagata aagttgctga agaaactttt gaaatttttg
     4441 tagaaaatct aacaaaaggt ttattaacga tttcttatct acttaatcca gaaattctca
     4501 tattaggagg tgggattctg gatagtaagg atattttgtt acctgaaatt caaagttctt
     4561 tagctaaaaa tgcaatggat aataggtttt tacctaaaaa tcttgtggca gctacattag
     4621 gaaatgaagc tggtcgtata ggagctgtaa aaaatttctt agatagaatt tctaataaat
     4681 agtatgtaag ataaggaggt gtcacaatga ctaactctgt attttcgaca atgcaagata
     4741 ttgagaatgt tgcaaccgat attataaaat catatgataa tgagatttat acttataaag
     4801 ctgtttccca agaagaattg gaaaaactag aaaaaagtta tgatgaaaaa agtcacgaag
     4861 aattagtttc aatagaaagc aatttagaaa tgaaacaaca gaaccttatt gatgaggtta
     4921 ataaaacaat caaggaaaat gatgcaaata ttcagtatat ttcatcaagt aggagaggag
     4981 aatttgtaga aaaaattatt ggtagggtgg tagaaaaata tggccattag tcagatgaaa
     5041 agaatctctc tactattttc taaaagtagt cttgatgatg ttttaaaaac tattcaagaa
     5101 ctagagtcag tgcagttccg tgatttaaag gttcaggata actggtcaga agctctagaa
     5161 aaagatgaag ttgtatttcc aactattcaa atttttcata cttctaattc caatcatggg
     5221 gttattgagg gaaatgatgc cttgacttat ttgatgaatc aacaacaaca tttagaagca
     5281 actgtagaga aattacaaga atacctaccg aaagaaaaca cgtttaaatt attgcagcaa
     5341 cctccgataa ctacctctta tgaagaatta gagaaatttg gtaaagctaa tgttgctgag
     5401 ggtgttctta aaaaagtgaa tcatcaaatt aacagagttc atgaattaga aagacacatt
     5461 caaagtaata atgaggaaat agagcgatta ataaagtggg aaaaattaga aattgttcct
     5521 gcgaatttag aacaattttc tttctgtaaa ggaaaagtcg gaacaattcc aaggactgaa
     5581 gataatcgct tatacaatag tcttttagaa aacaatattg aagttcaaga aatattttct
     5641 aatgatagag agtacggtgt tgttgttttc tatcagtcta gttactctat agattttgat
     5701 gaatacttat ttgaaccatt tgattattct agaaaggaat taccgaagca gcgagtagta
     5761 gatttagatc aagaaaacat gcagttaata actgaaaaag agaatattat cgcatcgttg
     5821 caagattcaa agaaatattt gatagattta caatggcaaa tagactatat tttatctatc
     5881 tatgctcgtc aaatctctaa gaataacttt ttgtgcactc cgcatctagt tgcattagaa
     5941 ggatggatag aagaaactcg tattttatat tttataaaag ttatggatga gcattttgga
     6001 cattctattt atatttatga atcggaaaca ttgacggata atcaagatga aatacctatc
     6061 aaattaacga atcattcttt aattgaacca tttgaattat tgacagaaat gtatgctctg
     6121 cccaaatatt atgagaaaga tcctacacct gtattagcac cattttactt tacatttttt
     6181 ggaatgatgg ttgctgattt aggctatggt ttactattgt ttttaggaac aatgttagca
     6241 ttaaaaattt ttcatctacc ttcagcaact aagagatttt taaaattctt taatatatta
     6301 ggggtagccg ttgcaatttg gggtggaatc tatggctcat tttttggata tgagttgcca
     6361 tttcatctga tatctacaac ctctgatgtc atgactatat tagtagtgtc agttgtgttt
     6421 gggtttatta cagtatttgc aggtttgtta gcttcaggac tacaaaaagt aagaatgaag
     6481 aaatatgcag aagcatataa ttcaggattt gcgtggtgtg ttattctgct tggcttgtta
     6541 tttattgctg ttggaatgtt gatgcctgat atgagaccgt tatttgtatt agggaaatgg
     6601 gtatctattt ttaatgctgt ggggattttg attgtttcta ttattcaaac caaaagcttg
     6661 tcaggtattg gagcaggatt gtttaatcta tataacattt catcttatat aggtgattta
     6721 gttagtttca ctcgattgat ggcattagga ttatctggag caagtatagc atcagctttc
     6781 aatttaattg ttggtttgtt tccgggaata ttggctaaac tgacaattgg attagtatta
     6841 ttcattcttt tacatgcgat caatattttt ctatcgttac tatcaggata tgttcatgga
     6901 gcacgtctga tatttgttga attttttggt aagttttatg agggtggagg aaaaccattt
     6961 caacctttga aggcttctga gaaatatatt aaggttatta caaagaatta atggaggata
     7021 tatataatgg aacatttagc aacttatttt tcaacctatg gaggagcttt cttcgctgca
     7081 ttgggaattg tattggcggt tggattaagc ggtatggggt ctgcttatgg agttggtaag
     7141 gctgggcaat ctgccgcagc tttactgaaa gaacagcctg aaaagtttgc ctcagctttg
     7201 atattgcaac tattgcccgg aacacaagga ttatatggtt ttgttattgg aattttgatt
     7261 tggttgcaat taactccaga acttcctttg gaaaaaggcg ttgcttattt ctttgtagct
     7321 cttccaattg ctattgtagg atacttttca gctaagcatc aaggaaatgt agcagtagcg
     7381 ggaatgcaaa tcttggctaa aagaccaaaa gaattcatga agggagcaat tttagctgcc
     7441 atggtagaaa cctatgcaat tcttgctttt gtcgtatcat tcattttgac ccttcgtgta
     7501 taagaaataa atttgcaatt caaaggaggt gtctaaatga gcaatttaga aaacttacga
     7561 gagtctgtta ttgaacaagc tcatgaaaaa gggcgtatga aattattgga ttccaaaaag
     7621 aagattgatg atgaatttga aatgcaaaag tcgctcatta taaagaaaaa agaagctgaa
     7681 catgaacgaa agttaaaaga attgcaacag aaatatcaaa taatttttca acaattaaaa
     7741 aataaggaac gccaatcaac gttagtatca aaacagaaaa tattaaaaga actttttcaa
     7801 tctgctttac tagaaatgga atcttggagt gcagataaag aaatggagtt catctatcga
     7861 attctggaac gatattcaca acaagaggtc atagtaacct ttggggaacg gactttagct
     7921 aaattcaatt tggaacaatt agagaaattg aaattctctt ttccaaatta tttatttagt
     7981 gaacaaccta tctcaaatga atcaggctta cttatttcaa tagg
//
LOCUS       DAVMCN010000074         7386 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVMCN010000074 DAVMCN010000000
VERSION     DAVMCN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.075"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..154)
                     /locus_tag="VYP85_001863"
     CDS             complement(<1..154)
                     /locus_tag="VYP85_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1882324.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKC"
     gene            complement(226..603)
                     /locus_tag="VYP85_001864"
     CDS             complement(226..603)
                     /locus_tag="VYP85_001864"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1882325.1"
                     /translation="MRRKFFEAPPKQADKSSLGAKGLAYCDQLFSLERDWEALPADER
                     LQKRQEELQPLIEDFFAWCRRQSVLSGSKLGRAIEYSLKYEETFKTILKDGHLVLSNN
                     LAERAIKSLVMGRSKRVHWTLLA"
     gene            complement(752..1342)
                     /locus_tag="VYP85_001865"
                     /pseudo
     CDS             complement(752..1342)
                     /locus_tag="VYP85_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1266..1460)
                     /locus_tag="VYP85_001866"
     CDS             complement(1266..1460)
                     /locus_tag="VYP85_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1882326.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1657..1980)
                     /gene="tnpB"
                     /locus_tag="VYP85_001867"
     CDS             complement(1657..1980)
                     /gene="tnpB"
                     /locus_tag="VYP85_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1882327.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1961..2146)
                     /locus_tag="VYP85_001868"
     CDS             complement(1961..2146)
                     /locus_tag="VYP85_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882328.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2450..4012)
                     /gene="guaA"
                     /locus_tag="VYP85_001869"
     CDS             complement(2450..4012)
                     /gene="guaA"
                     /locus_tag="VYP85_001869"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1882329.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4154..4852
                     /locus_tag="VYP85_001870"
     CDS             4154..4852
                     /locus_tag="VYP85_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1882330.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4895..5791)
                     /locus_tag="VYP85_001871"
     CDS             complement(4895..5791)
                     /locus_tag="VYP85_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1882331.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5800..6735)
                     /locus_tag="VYP85_001872"
     CDS             complement(5800..6735)
                     /locus_tag="VYP85_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1882332.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6732..>7386)
                     /locus_tag="VYP85_001873"
     CDS             complement(6732..>7386)
                     /locus_tag="VYP85_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="proteinase"
                     /protein_id="HEV1882333.1"
                     /translation="YIETLGMKALLEESAFLSLGDQTGLEKLVLEEAPSMRTRKVEGR
                     KKLARLIVKVENPLEIEGILSKTDSIHRLYKGQNGYAFEIFSPEDDLILIHAEDDIAS
                     LVEVGEKPEFQTDLASISLSKFEISMELHLPTDIESFLESSEIGASLDFIPAQGQDLT
                     VDNTVTWDLSMLKFLVNELDIASLRQKFESTEYFIPKSEKFFLCKDRNNVELWFEEV"
BASE COUNT         2241 a         1602 c         1373 g         2170 t
ORIGIN      
        1 tgcacttttc ttgtacaact ttagtccacg gtaaataggc ctctaaaacc tctttgttta
       61 cgagagtttc ctcgtttgga agacattcta gaagatagga tagatatttc tcactattta
      121 gttgatgacg tttagctgtt tccaataagc tcataataat agctcttgct ttagctcctt
      181 caaaaacttt gagaaaacaa ccaccctcgc ttttttaaac tgagcttagg ctaaaagagt
      241 ccagtggact cttttactcc gtcccataac caatgattta atggcgcgtt cagctagatt
      301 attggaaagg accagatgtc cgtcttttaa aatggtctta aaggtttctt catacttgag
      361 gctgtattca attgcccttc ctagttttga acccgataaa actgactgac gacggcacca
      421 agcaaagaag tcttctatta ggggttggag ctcttcttga cgtttctgta gtcgttcatc
      481 agctggcaaa gcctcccagt ctctttccaa ggaaaataac tgatcacaat aggctaatcc
      541 tttagctcct aaagatgatt tatccgcttg cttggggggc gcttcaaaaa acttccttct
      601 cacatgtgcc caacatccaa caagttcagc ttctgccagt tgactgacga taagcttcta
      661 gcggttcgca gtttaccaag cttagcgtcg ccttgctcct aaaccttgga ctgctatcgc
      721 ataggcagaa ctagaggact aaagtcctaa gttactgccg caacatgtca caatgcacat
      781 agccagaata atctcctagg aattcttgta ctactaaacc actccgacgc tgatcatggt
      841 ggtacagcgt gattgcttga ttttcagctt tcccagacaa aaaggtccaa tagtaggtca
      901 gctgactatc actctctagc accctataag aagtttcatc tgcatgaagt aagggcttga
      961 gtcaatagtc tcgttataaa ggggctttag gaataggagc tttcacgatt ttatcactcg
     1021 gatttttatc actgcatgct tggcatttgt aagcgtgttg gatatgatct atgcgtttta
     1081 attgcgcagg aataaagacc aattcttgtc cttgaagact ccctccaatc tcttttagat
     1141 ctccctgaca atcagggcaa atcctctctt ctacttgatg atgaacttct tctgaatcaa
     1201 attgggcaag aagagcttgg cgtttccctt tagatttctt acgtttgtag gtaatttctt
     1261 ctgtttcaac tgggaacatc tccatcttcc tcagatggag actcttcctc aaaaaggttg
     1321 agttgtccag aggggcaaac acttttctca gaggattttc catagagctt ttgagtcaga
     1381 taagccactt gttcacgcag aagggcaagt tcattggtga gactatcaat tgtagcactc
     1441 tgttgttgaa tgattttcaa tcttcttcca tgagcttccc tctctgtttt ctaactttat
     1501 tatactaaaa agaaagtcct catttcaata gaaatcacga ctttctgatg gatttatagt
     1561 aaaatgaaat aagaacagga caaatcgatc aggacaatca aatcgatttc taacaatgtt
     1621 ttagaagcag aggtgtacta ttctagtttc aatctactat atttttggag tgatagaaaa
     1681 gcccttcata agccaatcta cttgttcagg tgcgagagct ttgacatcct tttctgtact
     1741 tagccaagtc agttttccgt tctcaaagcg tttatataat atccaaaatc cttgaccatc
     1801 ccagtaaagg actttaaagc ggtctttacg tccaccacaa aagagaaaga cttgatcgga
     1861 gaaaggatcc aattcaaagt gggttttaac cagataagcc agtgaatcga ttccttgtct
     1921 catatccgtt ttcccacata cgagatagac ctgccctagg ctagatagat gaattgtcat
     1981 agagcaacac cttatccaaa agctgttcta tcatttcgag attgagagat tgaaaaaaac
     2041 ttacttcaag cttgccaata cgaattttaa gcagaatatc atttctcttt ttagaatcaa
     2101 aaggacgaga ttgtggaatc tctacaggaa caataggttg tggcattaaa atatcctcca
     2161 atagttttac tttactaata gtatacagga ggagctccat gaatgataga taccttgtta
     2221 tgacgcgctt actatattag aaagttggct ctctaattaa attaattctc attatatata
     2281 tcaaaagacc gcagtttgaa aactacggtc taattttttg tccaaatgta aaccacttgg
     2341 aactattatt caatttattc tttttagcaa atgttcccgt tttaatccca gttacagttt
     2401 ttaatcctct gtaaccgttg attttacaaa gcttttaatt tttttgcgat tattcccact
     2461 caactgttgc aggtggttta cttgtaatat cgtagacgat acggttaaca tgatccactt
     2521 catttacgat acgtactgag attttttgaa gtacttccca tggaattttg gcaaaatcag
     2581 cagtcatacc atcgatagaa gtgatagcac ggattgcaat cgtgtagtca tacgtacgac
     2641 cgtcacccat aacaccgact gaacgaacgc ctgtgttaac agtgaagtat tgccaaatat
     2701 cgcggtcaag tccagcttta gcgatttctt cacgaagaat agcgtctgat tcacgaacgg
     2761 tttcaagttt ctcttcagtg atttcaccca tgacacggat agcaagtcct ggtcctggga
     2821 atggttggcg ccatacgata tggtctggca taccaagctc tgtaccaaga gcacgaactt
     2881 catccttgta aagagtattg agtggttcaa tcaattcaaa ctgcatatct tctggaagac
     2941 cacccacgtt gtggtgtgac ttgatagttt gagctgtatc cgtaccagac tcgataacat
     3001 ctgtatataa agtaccttga gcaaggaatt tcacatcttt gagcttgctt gcttcgtcat
     3061 cgaatacata gacaaactcg ttaccgatga ttttacgttt ttgttcagga tcagaaacgc
     3121 cagcaagttt gtcaaggaaa cgtttagcag cgtctgcttt gacgatattc aaaccaaact
     3181 taccaccgag catgtccata acttgatcag cttcgccttt acgaagaaga ccgtggtcta
     3241 cgaagataca gatcaattga tcgccaatcg ctttttggag aagaacccca acgacagatg
     3301 agtcaacacc acctgataga ccaagaagga cacgtttatc accgacggtt tcacgaattt
     3361 ttttgatctg catgtcaatg aaattatcca ttgaccagtc acctttagcc ttacaaatgt
     3421 taagggcaaa gttacgaagg atatcatttc cgtatacaga atgacgaact tctgggtgga
     3481 attggatacc gtaaatgtgt ttatctgggt tttcgatggc tgcgtatggg cagtcagctg
     3541 atgtacctgt acgaacaaag tcagcaggaa tctcagtaac cgcatcacca tggctcatca
     3601 aaacagtctg ttcatcaggt gttgattcaa aaagcgctga tggtgtgtga gttagggttg
     3661 attgaccgta ttcacgattt ccagcatcac ctgcaggaac aacttttcct ccaagtttat
     3721 gggtcaataa ctgcatacca taacagattc ccaaaattgg aattccgagt tcgaagattt
     3781 ctgggtcaat atcaaatgaa ccatcttcat atacagaatt tggaccacct gatagaataa
     3841 ttcctacagg attgacttca cgaacttcag cagctgaaat tttatggctt tttagttctg
     3901 aaaaaacacc aatctcacgg atacggcgtg aaatcagctg gttgtactgg ctaccatagt
     3961 ccaatacgat gattttttct acatcttgca aatcagttga aatgttgctc atctttttcc
     4021 tttctcaaaa gaaatatctt ttcccaatat tctatcacaa ataagggcga attaccaact
     4081 aaacaaggcg aagtttgact ttttctagtt tattggggta caatagagaa aagatagaaa
     4141 tgaagtgaaa aatatgctac ctgcttatat gaaaatccat gatcagataa aaaaggatat
     4201 tgacgagtac cgttgggcta ttggtgagag gcttcccagt gaaagagatc tagctgagca
     4261 gtttgcggtc agtcgcatga ccctccgcca agccgtatct ctattagtcg aagaaggcgt
     4321 cttagagcgc cgtgtaggaa gcggcacctt tgtttccagt actcgagtac aagaaaagat
     4381 gcgagggaca accagtttta ctgaaattgt caaatcccaa ggtaaagttc cctctagcca
     4441 gctcatttcc tacaaaaaaa ccattcccaa tgagcaagaa gttgccaagc taggaatttt
     4501 tccaacggac aatattatcc gaatggagcg ggtccgctat gccgaccaag ttcccctagt
     4561 ttatgaagtt gcttctattc ctgaaaaatt cattaaggac tttaaaaaag aagaaatcac
     4621 cagtcatttc ttccaaacct tgcaaaaaca tggctatcgt atcggcaaat ctcaacagac
     4681 catctatgct cgccttgcta aagaaaagat tgcccactat ttggaagttg aaaaaggaca
     4741 tgctattctt ggattgaccc aggtttccta cctagaagat ggtactgctt ttgaatacgt
     4801 aaaaagtcaa tatgtaggcg aacgctttga attttatctt gaaaataatt agattaccac
     4861 gcaaaaactc tctgtcacga acaaagagtc ttttttattt ttctaagaat aaatctttca
     4921 aagaaatcaa agttacagca aacaatatca ttgccatacc aataaaatca atgggataaa
     4981 attgttcatt cattattaag aaggcaaaga aaaccgccga tattggctca attgaagcca
     5041 acaagcttga cttgaccggt cctatcagac tggctccttt aaggaaagct gtataggcaa
     5101 agacagtccc gataaggata atgcctgcaa acgcaaggag aaaatcaaga ctagtcggga
     5161 tatcggcctg tagaacccct gtaaaaggaa gggcgaccaa acctgctatg accatcccca
     5221 caccaatgac caagctgctc ccccactttt taatcaaggc tatgggtaaa atgatataca
     5281 gagcataagt caaggcagaa aagagacccc agaacaggcc agcaggtgtc atggataact
     5341 ggtccaactg cccatgtgtt gcgatcagga aggttcctcc gatggcgaat atgatggaaa
     5401 ctatctctcc cagtgtcggt gccaccctat ccttgataca gctataaatt aaaattccga
     5461 caggacaaac atactgaagc accgtcgctg ttcccgcatt ggtctcctga atagcagaca
     5521 gataggcgaa ttggttgaga aaaagaccaa tcagagcaaa aataagaaga gacagcaaac
     5581 tctttctatc ctttaaaaag accagtattt tatcctttgc agtagcataa gccaagagca
     5641 tgagaattcc accagcgatt aaaagacgca agttggtcaa gaccagagcc gaaattccgt
     5701 gtgccattag gtattggcca ctcgttcctg acaaccccca agcaatacca gccacaactg
     5761 ttagtaaagt cccttttaaa ctatttgaca tgtctctcct tactcttctt tgcgaatcaa
     5821 gttcatcact tgattgcggt ctaatatcca ttgagctctc tcgtcctttt cataggtacg
     5881 attcgatagg aaaatagtgg cttcttgctt ctgacgattc cacatgataa aggtacctgt
     5941 atagcccgta tggtctagcc aatctccttc caaattccat gctaaagaac gttccttgtc
     6001 atccaaagga gaaaaatttt gatttaagtc tcttgcaaaa tcatctgcta aatagtgttc
     6061 taaaaagatt tgtaaatcct ttatagtcga aaataaacca gcactcccag catgtctacc
     6121 caggagacga gccttgggat catgcactat gcctgcctct acacctctaa ctgttggaac
     6181 agcaagctca actggcccaa acttggtttc cgtcattccc caaggtttcc agacttgatc
     6241 ctttaaaatc acatccaaat cttgattaaa aattctttcc aaaataaagc ccaacagcaa
     6301 aaaatggaca tccgaataaa gaaaggctgg ctgacttcgt ctgttgagat gaaacatcgc
     6361 ttcctttaat tcaggggctg ttaaaagatc acgattagga ataaaaggat caaggtctgt
     6421 tgcatgagtc aagagctggc gaatagtgat gtctggataa tcactctcag gtaaaaaatc
     6481 tattaccagt ctatcaatat ctaattgacc tatttcccac aagaaggtac aaactgtgcc
     6541 aaccccaaca accttgctga cactagctag gtcataaact agtcctgcct cagtctgcaa
     6601 gccatgctct gggtcactct ggcctaaata gaactctgtc cattgattgt ccttaaaata
     6661 cgcaaaagag gctccgggat aaattcctgc ctcgatttgt tcttctattt ttttaataat
     6721 cttggtccac ttcatacttc ttcaaaccac aattcaacat tatttctatc tttacaaagg
     6781 aagaattttt cagacttagg aataaaatat tcagtagact caaacttctg gcgaagactt
     6841 gctatgtcta attcattgac caagaacttg agcatagata agtcccaggt aaccgtattg
     6901 tccacagtca aatcctgccc ctgagctgga ataaaatcaa gggatgcccc aatttcagat
     6961 gattccaaga aactttcgat atcagttggg agatgtaatt ccatagaaat ctcaaattta
     7021 cttaaagaaa ttgatgccaa atctgtttga aattcaggct tttctcctac ttctactaga
     7081 cttgctatgt catcttccgc atgaatcaaa atcaaatcat cttctggtga gaaaatttca
     7141 aaagcgtagc cattttgacc tttatataat cgatgaatcg aatctgtttt agataagatt
     7201 ccttcaattt ctaagggatt ttccaccttg acaatcaatc tagctagttt ttttcttccc
     7261 tctaccttac gagtacgcat actgggagct tcttctaaaa ccagcttttc aagacccgtt
     7321 tggtcaccta gtgacagaaa ggccgattct tctaacaagg ccttcattcc aagggtttca
     7381 atataa
//
LOCUS       DAVMCN010000075         7350 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVMCN010000075 DAVMCN010000000
VERSION     DAVMCN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7350
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.076"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..327
                     /locus_tag="VYP85_001874"
     CDS             <1..327
                     /locus_tag="VYP85_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1882334.1"
                     /translation="LTNGELIAPMTYEETMTSDFFEAWFQKFFLPTLNTPSVIIMDNV
                     RFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALL
                     SCSCFN"
     gene            388..1350
                     /locus_tag="VYP85_001875"
     CDS             388..1350
                     /locus_tag="VYP85_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1882335.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1527..2534
                     /gene="gap"
                     /locus_tag="VYP85_001876"
     CDS             1527..2534
                     /gene="gap"
                     /locus_tag="VYP85_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1882336.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2602..3438)
                     /locus_tag="VYP85_001877"
     CDS             complement(2602..3438)
                     /locus_tag="VYP85_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1882337.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3564..5759
                     /locus_tag="VYP85_001878"
     CDS             3564..5759
                     /locus_tag="VYP85_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1882338.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTSGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5812..5964
                     /gene="rpmG"
                     /locus_tag="VYP85_001879"
     CDS             5812..5964
                     /gene="rpmG"
                     /locus_tag="VYP85_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1882339.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5974..6150
                     /gene="secE"
                     /locus_tag="VYP85_001880"
     CDS             5974..6150
                     /gene="secE"
                     /locus_tag="VYP85_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1882340.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6205..6741
                     /gene="nusG"
                     /locus_tag="VYP85_001881"
     CDS             6205..6741
                     /gene="nusG"
                     /locus_tag="VYP85_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1882341.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6863..7342
                     /locus_tag="VYP85_001882"
     CDS             6863..7342
                     /locus_tag="VYP85_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1882342.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT         2312 a         1260 c         1600 g         2178 t
ORIGIN      
        1 ctaaccaatg gtgagttaat cgctccaatg acttacgaag agacgatgac gagcgacttt
       61 tttgaagctt ggtttcagaa gtttttctta ccaacattaa acacaccatc ggttattatt
      121 atggataatg taagattcca tagaatgggg aagctagaac ttttatgcga agagtttggg
      181 cataaacttt tacctcttcc tccctactcg cctgagtaca atcctattga gaaaacatgg
      241 gctcatatca aaaagcacct caaaaaggta ttaccaagtt gcaatacctt ttacgaggct
      301 cttttgtctt gttcttgttt caattgacta tatatcacgg atacagttgg gaaagaagct
      361 attaattatt tggagagtcc ttttgggatg aacatgtcaa atattactat agatgggcaa
      421 gaaatggatc tgagtcaaac gatgccttct tatgctcaag tagtgagtct ttatgatgat
      481 acaagtatct ctgttagtaa taatgagacg gacaaagtgt tggctggatc cctctatact
      541 gatacaaatg aacagggatt aacgattcca agcagtttac taaaaaattg gaatgaacag
      601 acaggaaaaa atttgacagc taatgatctt attggcaaat cagtctcagc cagcattgta
      661 gaaagtgctg ccgaaactag taagattgct caatttcaaa cgaagattgt acgtgtaatc
      721 aatgatgaag atgacatgga ggacagcaac agtttcatgc tgtctcatca aatggaaacg
      781 attttgaaag aggctggatt tacgaaagct gtatcttatt ttatcttgga actcaaagat
      841 ccatcacaga caaaagtagt aacagaagaa ttacagaaaa ataagaagta tactgtgctt
      901 tctcaacaga gagttcttga tattgtgatt acctttattc gtgttattca gggattattg
      961 attgtgcttt catcacaagc tattgtggta gcagcggtta tgattggtat cattatttac
     1021 atcaatatca tgcaacgttc caaggaaata ggtgtcatga aagcagttgg ttatcagaat
     1081 cgtgatgtca aaggaatttt tatttacgag gctatctgga ttgtaggcat cgccttgctg
     1141 ctggcatttt tggttgcaca aggggtggga agtttggcga atgcgattgt aagtcacttt
     1201 tacccatcca tcactaaggt ttttgaatta aatcttttat ctgttttagg aactctagtt
     1261 ttcgctctat tacttggtta tgtctcagcc tacttcccgg cgcgtaagat tagtaaaatg
     1321 gatcctgtag aatcgttacg ctatgaatag taagggattc cttgatttac agtcttaaaa
     1381 agaaactaac atagaaaaac aatggccata cttgcaattc aactcaaata gttgtataat
     1441 aggtttgttg aaaggtgatt tgtagtgatt caagttactc ttttcacaat aaaaatttca
     1501 tgattttcat aaggaggaaa tcactaatgg tagttaaagt tggtattaac ggtttcggac
     1561 gtatcggtcg tcttgctttc cgtcgtatcc aaaacgtaga aggtgttgaa gttacacgca
     1621 tcaacgacct tacagatcca gttatgcttg cacacttgtt gaaatacgac acaactcaag
     1681 gtcgtttcga cggtactgtt gaagttaaag aaggtggatt tgaagttaac ggtaaattca
     1741 tcaaagtttc tgctgaacgt gatccagaac aaatcgactg ggctactgac ggtgtagaaa
     1801 tcgttcttga agctactggt ttctttgcta agaaagaagc agctgaaaaa caccttaaag
     1861 gtggagctaa aaaagttgtt atcactgctc ctggtggaaa cgacgttaaa acagttgtat
     1921 tcaacactaa ccacaacgtt cttgacggta ctgaaacagt tatctcaggt gcttcatgta
     1981 ctacaaactg cttggctcca atggctaaag ctcttcaaga caactttggt gttgttgaag
     2041 gattgatgac tactatccac gcttacactg gtgaccaaat gatccttgac ggaccacacc
     2101 gtggtggtga ccttcgccgt gctcgcgctg gtgctgcaaa catcgttcct aactcaactg
     2161 gtgctgcaaa agctatcggt cttgtaattc cagaattgaa tggtaaactt gacggatctg
     2221 cacaacgcgt tccaactcca actggatcag ttactgaatt ggtagcagtt cttgaaaaga
     2281 acgttactgt tgatgaagtg aacgcagcta tgaaagcagc ttcaaacgaa tcatacggtt
     2341 acacagaaga tccaatcgta tcttcagata tcgtaggtat gtcttacggt tcattgtttg
     2401 acgcaactca aactaaagtt cttgacgttg acggtaaaca attggttaaa gttgtatcat
     2461 ggtacgacaa cgaaatgtca tacactgcac aacttgttcg tactcttgaa tacttcgcaa
     2521 aaattgctaa ataattcttg agttgataga aagcaaggct ttgtggtctt gcttttttat
     2581 atggaaaaat ggatgacacg atcatccatt cttttttaat tctttttcaa atgtatttga
     2641 aagggtagtg aaagttagct tctctaaagt aagtgggtgg gtaaaggaaa gtcggaaggc
     2701 atgaagcata agccggcttg tctttgattt actattatag agagggtctc ccaggatagg
     2761 aagattatga tgcgaaaggt gcacacgaat ctgatgggtt cgccctgtct ttagcttgca
     2821 atgagccaag gaagtcttgt ttgagaattg ctttaatctg cttacatgcg tttcagcata
     2881 ttgcccattt tttgcatcaa ctattctttt tctacgatca tggcgatcac gtccaatttt
     2941 gtctctgaaa acaagttctt ttctgttgat atttccatca actagagccc aatattctct
     3001 agaaatctct tttttctcca ataagcgatt gagaatgggc aggataaaag gatttttggc
     3061 aaagagaact aagccactgg tttccatgtc cagacgatga acgacatagc aggtttggcc
     3121 aacataggta ctgacatggt taagaagggc aatttcgttt ggttgattac catgcgtttt
     3181 catcccctct ggtttgttta caataatcaa gtgttgatct tgataaactt cctgcactaa
     3241 gtctgggttg ccccaaggga tcgtcttttg gggataatct tcctcgtcaa aagtcaactg
     3301 gcaaacatct ccaggattta cgatttcgtt ccagtggact tcttcttgat ttatcaaaat
     3361 atgtttcttg attctcaaaa aatgacggat ttttctaggg atgaggagtt gttcctcaag
     3421 taattgcttt accgtcattt gaggtagaga ggcgggtaat gtaaatgtga attgcataca
     3481 gatattgtaa caaaaaaagc cctatttgga taggaaatag ctaaattctt gtcttcctat
     3541 gatgaagatg ataaaataaa cgcatgaaat tagataaatt atttgagaaa tttctttctc
     3601 tttttaaaaa agaaacaagt gaactagagg actctgattc tactatctta cgtcgctctc
     3661 gtagtgatcg aaaaaaatta gcccaagtag gtccgattcg aaaattctgg cgtcgttatc
     3721 atctaacaaa gattatcctt atactaggtt tgagtgcagg cttgctagtt ggaatctatt
     3781 tgtttgctgt agccaagtcg accaatgtca atgatttgca aaatgccttg aaaactcgga
     3841 ctcttatttt tgaccgtgaa gaaaaagagg ctggtgcctt gtctggtcaa aagggaacct
     3901 atgttgagct gactgacatc agtaaaaact tgcagaatgc tgttattgcg acagaagacc
     3961 gttctttcta taaaaatgac gggattaact atggccgttt cttcttggct attgtcactg
     4021 ctggacgttc aggtggtggc tctaccatta cccaacagct ggctaaaaac gcctatttat
     4081 cgcaggatca aactgttgag agaaaagcga aagaattttt ccttgcctta gaattaagca
     4141 aaaaatatag taaggagcaa attctaacca tgtaccttaa caacgcttat tttggaaatg
     4201 gtgtgtgggg tgtagaagat gcgagtaaga aatactttgg agtttctgca tcagaagtga
     4261 gtctggatca agctgcgact ctggcaggga tgctcaaggg gccggaactg tataatccct
     4321 tgaattctgt agaagattct actaatcggc gcgatactgt cttgcagaat atggttgcag
     4381 caggatatat tgataaaaac caagaaaccg aagctgctga agttgatatg acttcgcaat
     4441 tgcacgataa gtatgaagga aaaatctcag attaccgtta cccctcttat tttgatgcgg
     4501 tggttaatga agctgtttcc aagtataatc taacagagga agagattgtc aataatggct
     4561 accgcattta cacagagctg gaccaaaact accaagcaaa tatgcagatt gtttatgaaa
     4621 acacatcgct atttccgagg gcagaggatg gaacgtttgc tcaatcagga agtgtagctc
     4681 tcgaaccgaa aacaggggga gttcgtggag ttgtcggtca agttgctgac aatgataaaa
     4741 ctggattccg gaatttcaac tatgcaaccc aatcaaagcg tagtcctggt tctacaatta
     4801 agcctttagt tgtttataca ccagcagttg aagcaggctg ggctttgaat aagcagttgg
     4861 ataaccatac catgcagtat gatagctata aggttgataa ctatgcaggg atcaaaacaa
     4921 gtcgagaagt tcctatgtat caagccttgg cagaatcgct taatctacct gctgttgcca
     4981 ctgttaatga tttgggtgtt gacaaggctt ttgaggcagg cgaaaaattc ggactcaaca
     5041 tggaaaaggt cgaccgtgtt cttggtgtcg ccttgggaag cggtgttgaa accaaccctc
     5101 ttcaaatggc tcaagcatat gctgcctttg caaatgaagg tttaatgcct gaagctcatt
     5161 ttattagtag aattgaaaat gctagtggac aagttattgc gagtcataaa aattcacaaa
     5221 aacgggtgat tgataagtct gtagctgaca agatgaccag tatgatgttg gggactttca
     5281 ccaacggtac cggtattagt tcatcgcctg cagactatat tatggcaggg aaaactggaa
     5341 caactgaagc agtttttaat ccggagtaca caagtgacca gtgggtaatt ggttatactc
     5401 cggatgtagt gattagccac tggcttggct ttccgaccac tgatgaaaac cactatctag
     5461 ctggctctac ttcaaacggt gcagctcatg tctttagaaa cattgccaat accattttac
     5521 cttatacgtc aggaagtacc tttacggttg aaaatgctta taagcaaaat ggaattgcac
     5581 cagccaatac aaaaagacaa gtacaaacca atgataatag ccagacagat gataatttgt
     5641 ctgatattcg agggcgtgcg caaagtctag tagatgaggc tagccgggct atctcagatg
     5701 cgaagattaa ggaaaaggct caaacaatat gggattcgat agtcaatcta tttcgctaag
     5761 atgcttgtca aagcctagct ttcttgttat aatggataag atggaggcgt tatggcacta
     5821 aaaaaagcaa gcctagcttg tgcggtttgt ggttcgagaa actattcaat caagatcagc
     5881 ggaaacccca agcctacacg actagaagta aataaatttt gtaagcattg tggcaagtac
     5941 actacacata gagaaacgag ataggagaga gcgatgcgtt ttattggaga tatttttaga
     6001 cttcttaaag acacaacgtg gccaactcgc aaggaaagct ggagagattt tcgttctatc
     6061 atggaataca cagctttctt tgtagtaatt atttacattt ttgaccagtt gattgtttca
     6121 ggtttgattc gatttattaa cattttttag aagattagtg gagttaatta cactagaaat
     6181 cttctattta tgaaaggaaa tatcatggat agttttgata aaggatggtt tgttttacaa
     6241 acttattctg gttatgaaaa taaggtgaaa gaaaatctat tacaacgtgc acaaacctac
     6301 aatatgttgg ataatattct acgcgttgaa attccaacac aaacagtgca agttgaaaaa
     6361 aatggaaaga gaaaagaagt agaagaaaat cgctttccag gttatgttct tgtagaaatg
     6421 gtcatgacag atgaagcttg gtttgttgtt cgaaacacac caaatgttac aggatttgtc
     6481 ggatcacacg ggaacagatc aaaaccaact ccattattgg aacaagaaat tcgtgacatt
     6541 ttggtatcta tgggacaaac tgttcaagaa tttgatttcg atgttgagat tggtcaaact
     6601 gtacgtatta ttgatggtgc ttttgcagac tacactggta agattacaga aattgataat
     6661 aacaaagtga aaatgattat ctctatgttt ggtaatgaca cagttgcaga agtaaaccta
     6721 aaccaaatcg cagaattata accctgagag aggctggagc ctctcttttt tgtgcagttt
     6781 aggagctaaa gggaacagaa tggagaaaat ggaacaaatg tgttttctaa tctgttagac
     6841 tgtatctaga aaggggaaaa ttatgattaa agaattgtat gaagaagtcc aagggactgt
     6901 gtataagtgt agaaatgaat attaccttca tttatgggaa ttgtcggatt gggaccaaga
     6961 aggcatgctc tgcttacatg aattgattag tagagaagaa ggactggtag acgatattcc
     7021 acgtttaagg aaatatttca aaaccaagtt tcgaaatcga attttagact atatccgtaa
     7081 gcaggaaagt cagaagcgta gatacgataa agaaccctat gaagaagtgg gtgagatcag
     7141 tcatcgtata agtgaggggg gtctctggct agatgattat tatctctttc atgaaacact
     7201 aagagattat agaaacaaac aaagtaaaga gaaacaagaa gaactagaac gcgtcttaag
     7261 caatgaacga tttcgagggc gtcaaagagt attaagagac ttacgcattg tgtttaagga
     7321 gtttactatc cgtacccact aggaagtcat
//
LOCUS       DAVMCN010000076         6158 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVMCN010000076 DAVMCN010000000
VERSION     DAVMCN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.077"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..998)
                     /gene="phtB"
                     /locus_tag="VYP85_001883"
     CDS             complement(<1..998)
                     /gene="phtB"
                     /locus_tag="VYP85_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1882343.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKR"
     gene            complement(1156..3606)
                     /gene="phtA"
                     /locus_tag="VYP85_001884"
     CDS             complement(1156..3606)
                     /gene="phtA"
                     /locus_tag="VYP85_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1882344.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3859..5592)
                     /gene="ptsP"
                     /locus_tag="VYP85_001885"
     CDS             complement(3859..5592)
                     /gene="ptsP"
                     /locus_tag="VYP85_001885"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1882345.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(5598..5861)
                     /locus_tag="VYP85_001886"
     CDS             complement(5598..5861)
                     /locus_tag="VYP85_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1882346.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT         1645 a         1290 c         1152 g         2071 t
ORIGIN      
        1 attcgttttt ccaattcaga catttgttca taagggataa agtggtaatg gttaccatga
       61 gggacagcta cacctctggc ggttcgactt gtgatttgcg ctgggtcgaa aataaggcca
      121 tcagattcca catggcgttc tgataagggt ttagcataca attcacgtaa aaggcttgaa
      181 atgttttccc cttgattttg atgataagtt ggagtgacag tcagattgtg gttctctgac
      241 aatcttggtt gagctggatt tgcattataa ctagaacttg aagaaggacg agatccctgc
      301 ttcccattcc aataggcttg ggcagcagct aactcgctag ctgataactc attcttagga
      361 atgtaatggt aatggtcgcc gtgaggaacg atataagcat cacccgtgtc ctcaatgata
      421 tcagatgcat tgaagatata cccatcatcc gttgtataac gtccttgggc tctggctgca
      481 gcaacagcat tatctgctct tgagttatga ttatgactgc gttcctgctt ctgacgttta
      541 atctcttctt ttgtccgaat attatccgca tgagctgcat ccttaaggta aacatagtat
      601 ttaccgttta ccttaatgac ataaccaccc ttgatttcat tgacaatgtc tgaatccttc
      661 aactgataat tcggatcttt catgaggagc tcttcactga tgatggcatc ataaggaacc
      721 ttgccattat agtaatgata atggtctcca tgagaggtca cataaccttg atccgtaatc
      781 ttgataacaa tttgttcggc gttgatcccc tccctcttac tgacttcatc tggtgtcaag
      841 ttttctgcct tttgaccagc ctgatcacca tctatataag caactcgatt agactctttc
      901 ttatcctgac cagcttggta acgtccaagc tcataggaac aaacacttag ggcaaggact
      961 gccactgaac ctgctagata ttttttattg attttcattc tttcctcttt tcttaagtat
     1021 atttgattca ctataaagta ataaaccggt taattaacta gttaatagtt tactcttttt
     1081 aatattgctt gtcaagaatt ttacatatat acataataaa aatgaaagcc tctttatcga
     1141 gactttcatt tttcattagt ttattttttc cttacttaca gatgaaggat tacttccttt
     1201 taacaacgca agtaattttt ctgcttctgc catgatacta ttgttatcca taatttgaag
     1261 agtcaaatta tttcgtaaac cagctagagt ttctgttgca ttggctttca gactagaatc
     1321 cgttactttc gcaagcaaaa cttctgcttc tttgagttgg gcttctactt tttcagtctc
     1381 tacttgaggg acttctggct cagcaggtgt ttcctctact ggctcttcat ccgctttgaa
     1441 gttcttattt ggatcttcac tgtggtcttt cttgcctaac acatgctcac tggcattgcc
     1501 ccatccatca ttagaatgtg gacgttcgtc agggtgttct acgtagtact taatcgtcgc
     1561 aaacaaatct tccaaggtat agccatttgg agctttgtat gtgtgatcat caaaccaagc
     1621 aaatttaatg ttatggtaat gatccttatg aggaataatc aaattaccgt ttttaacctc
     1681 aactgtatgc tcaaccatat atggaagtcg aacgagtgga attcgttttt cccctttcac
     1741 acgattgtaa atagctgctg cactatctcc agttggattt gctttaacat ctgcgtctgg
     1801 agatggaggt aggatacctt tttctttagt ataggcttga gctgcaactt tttccttatc
     1861 agaaaggctg tcttttccaa tccagtgact atggcccata tgaggcgtta catatgcatc
     1921 tccttcatca ctgattatat catgttcatc aaaaatataa ccatctgacg ttgtatactt
     1981 atcagctaat tgagcaatac gaacttcgtc ttcagtatac tcaatttgag aatttggctt
     2041 gccaagtcgc tctggatggg taattggtgc taggaatgcc aataaatcat ctaccaattt
     2101 ttctttatta gtcgattcat cattcaagcg ttctaataat ttgtctaagg cttggaaatc
     2161 agaattacga cccttatttt caaacaaggc tttatgagcc tcagttaaca gattatatgc
     2221 tttatcataa aattcttggt cacgaggagc aacattttct tttttagcag ttaaagtgtg
     2281 tgaaacactc tcttgttttg ataacttgct ttcaagattt ttaacagttt cagatggtaa
     2341 atctttcgca aagacataac gagagatgcc cttttcttcg aatacatatc cttccccaac
     2401 ttttcgtacc agctgactaa ccaaagaaga atttgagtct attttaagat ttggtgcagg
     2461 ttgcgggcct ggactaggtt ccggagtcgg ttgtggactt ggttgttctg gccttgaatc
     2521 tggtacccaa tggtttgaac gataacgaag gggaataata cgagcgattc gttcttccaa
     2581 ttcagacatt tgagagtaag ggatgaagtg gtaatgatct ccgtgtggca ctgcaacacc
     2641 tctagctgtt cgacttgtga tttgcgctgg gtcgaaaaca aggccatcag attctacatg
     2701 tcgttgactc aaaggcagtt tgtagagctg tttcaagaga ctatcaatgt cattactttg
     2761 acttgtttga ctgttagtgt tgctgttgtt gcttgtgtta gtatttgtag ttcctggatt
     2821 gcttacagaa ggtacccagt ttgttcttga agtgttatcg ctattttgtc ggcgataggt
     2881 tcttgaattt gacagatttc cccgaccaga taggaaggct tctgcagcag ccaactcgct
     2941 agctgataac tcattcttag gaatgtaatg gtaatgatct ccatgaggaa cgatataagc
     3001 atcaccagta tcctctatga tatcagaagc attaaagata taaccatcat ctgtagtata
     3061 gcgtccttgc gaacgtgcca aggcaacagc accatcgttt cttggagtcc caccttcacg
     3121 atgttgacta tgttcttgtt tttgtcgatt gatttcctct tttgtacgga cgttatccgc
     3181 gtgggcagca tccttaaggt aaacatagta ttttccatct accttgataa catatccacc
     3241 cttgacctca ttaacaatat cctcatcttt tagcttatag ttcggatctt tcatgagtaa
     3301 ttcttcactg aaaatcgcat cataaggaac cttaccattg taataatgat agtggtcgcc
     3361 atgtgaagtg acatagcctt ggtctgttat cttgatgacg atttgctcag cattgattcc
     3421 ttcacgcttg ctaacctcat caggagtcaa attctccgtt ttttgcgtcg cttgttttcc
     3481 atctatatag gaaacacgat tattttcctt aaccgttcta gcttgataca gtcccaactc
     3541 gtaagaacaa acacttaaaa tcaaagctgc cgcagaacca acaaggtatt tcttattaat
     3601 tttcatcgaa actctctttc tatttgatat ttctagttgc aattcatttc taaattgcag
     3661 aaactcctct ctattactta actggttaat agtttactcc taaatctcca acttgtcaag
     3721 aattttatga accatttaag tattttttgt tctgactact actttttcaa gaaaatcttt
     3781 ctataagaaa gattttcttg aaaattcttt ttaaaatatc aaaaaaatcc ctgtaactga
     3841 gttgcaggga cttttcgatt aatcaaaatt aacgtattct ttttgaagtt caagaacttc
     3901 ttccattgtt gagcattctg taagggcacg gtttgcgtac tcttccatct tagctgtgtc
     3961 gagtttcttc atcaagctgc gtgtacgaag tacagatgtt gctgacatag agaactcatc
     4021 caagcccatt ccgacaagaa gtggaacagc ttgttggtca ccagccatct caccacacat
     4081 accagcccat ttaccttcag cgtgagctgc tttgatcaca ttgttaatca agcgtaggat
     4141 tgatgggttg tatggttggt aaaggtatga aacttgttcg ttcatacggt ctgctgccat
     4201 tgtatattgg atcaagtcgt ttgtaccaat tgagaagaag tcaacttctt tagcaaattg
     4261 gtctgcaagc atagccgctg caggaatctc gatcatgata ccaacttgga tgttatccgc
     4321 aactgcaaca ccttcagcaa gaaggtttgc tttttcttca tcaaagactg ctttcgctgc
     4381 acggaattct ttcaagagcg caaccattgg gaacatgata cgcaattgac cgtgaacaga
     4441 cgcacgaaga agagcacgga tttgtgtgcg gaacatagca tctccagtct cagagataga
     4501 gatacgaaga gcacggaatc caaggaatgg gttcatttcg tgaggcatat cgaagtaagg
     4561 aagttcctta tctccaccga tatccattgt acgaacgaca acaggtttac cgttcattcc
     4621 ttcaagaaca gccttgtatg cttcatactg ctcatcttca gttgggaagt cttgagaatc
     4681 catgtacaag aactctgtac ggtaaagtcc aacagcttct gcaccgttgt tgttaacacc
     4741 ttcaacgtct tttggagtac cgatattagc agccaactcg aagtgtttac cgtcagcagt
     4801 cactgtttga gcatctttca agagcgccca ttcagctttt tgtttcgcat aagcttcacc
     4861 agctgcttta aattctgccg cttgttcatc agttgggttg ataataacct caccagtgat
     4921 cccgttaaca gcaaggatgt caccgtcttt aacgatttca gtgatgttgt ttgtacctaa
     4981 tacagctgca atttcaagtg tacgtgccat gatagctgag tggcttgtac gtccaccgat
     5041 gttggttaca aaagctttta caaagttttt gtccaattga gctgtatcag atggtgtcaa
     5101 gtcatgtgca atcacaatca cttcttcatt gatagaagct gggtttggca attttttacc
     5161 aagaaggttt gccaatacac gttttgtcac atcgcggata tccgctgcgc gttcttgcat
     5221 gtatgggttg tcttccatgc cttcaaagat agtgataaac atatctgtaa cttctttcag
     5281 acctgcttct gcattcactt tcttcgcacg gatagtttcc ttgatttggc tgatcatttc
     5341 tgggtcagca agaaccatta agtgagcatc aaaaacttga gctgcttctt caccgagcgt
     5401 acctactgct ttctcgcgaa taacagaaag ctcgtcttgt gatgcctgta gagcggcatc
     5461 aaggcgagct tcttctgcgt ttgtatcttc gactgtaata gtctcaaatg acaaatccgg
     5521 ctgaacgagt agatatgctt ttgcaactgc aacaccgtca gatgctgcga ttcctttaag
     5581 catttctgtc atttccctta tgccaatcct tctttttcca ttgtttctga gattgcagcg
     5641 atagcgtcat ctgcatctgc accttcagct gagatagtta cgtcagcacc ttggccaaca
     5701 ccaagactca taacacccat aattgattta aggttaactg atttaccttt gtactcaaga
     5761 gtgatatctg aagcaaattt gctagcagtt tgtaccaaca atgttgctgg acgtgcgtga
     5821 atacctgttt ctgccactac gtggaaatct ttagaagcca tagtttgact ctccttttgt
     5881 tctttctttt tttgagttat atgtgataac ccttacaatt tagtattata ccatcttcta
     5941 ggattttttt caagcatttt ctggattttc cttcaatttc ctttcagata acttgctgaa
     6001 aatcttctat cctagataac aaaacacagg atatagtttc tttaaaaaca atttatagga
     6061 taatcattgc tatttcacaa tacaaacact atatattgtg tttatatata aaaacaacaa
     6121 aagaacacca ctatatttag ttcaaatcat tgacaaaa
//
LOCUS       DAVMCN010000077         6153 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVMCN010000077 DAVMCN010000000
VERSION     DAVMCN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.078"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            219..1988
                     /locus_tag="VYP85_001887"
     CDS             219..1988
                     /locus_tag="VYP85_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1882347.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MIMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            2012..3967
                     /locus_tag="VYP85_001888"
     CDS             2012..3967
                     /locus_tag="VYP85_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1882348.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTIN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            3969..4406
                     /locus_tag="VYP85_001889"
     CDS             3969..4406
                     /locus_tag="VYP85_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1882349.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYESGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLAGAQSKEEVLRLFDAVE"
     gene            4468..5604
                     /locus_tag="VYP85_001890"
     CDS             4468..5604
                     /locus_tag="VYP85_001890"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1882350.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFKNPFIADEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1890 a         1034 c         1251 g         1978 t
ORIGIN      
        1 ttaatttcat aataaaaaca ccccaaaagt tagatttttt ctgtctaact tttggggtgt
       61 agttcatgta cacctgatat gatgcgtttt ataattttta agcctttttg cccagcctcg
      121 tcaaaagtaa tgttttgaca caaaatctgt gacaaaactt tagttttaaa ggtttttaac
      181 tttgtatata ctagttttaa gaaaaggagg atgatctaat ggaagaaaaa gtatcattga
      241 aagtcagggt tcaaaaacta gggacatcgc tttcaaatat ggttatgccc aatattggag
      301 catttattgc ttggggagta ttgactgccc tctttatcgc tgatggctat ctgccaaatg
      361 aacagttagc tactgttgtt ggtcctatgt taacgtattt attgccaatc ctgattggtt
      421 acacaggtgg atatatgatc catggccaac gtggtgccgt tgtaggagct attgctactg
      481 ttggtgcaat cacaggttct agtgttccta tgtttatcgg agctatgata atgggcccac
      541 tgggaggatg gactatcaag aaatttgatg agaagttcca ggaaaaaatt cgtcccggat
      601 ttgaaatgtt agttaataac ttctcagctg gtctcgttgg ttttgcatta ttgcttttgg
      661 ctttctacgc aatcggtcca gtcgtatcga ctcttactgg agctgttggg aatggtgttg
      721 aggctattgt caatgctcgc ctccttccta tggctaatat tatcatcgaa ccggctaaag
      781 tccttttcct caataatgcc ctcaatcatg gcatttttac tcctctggga gtagaacagg
      841 tagctcaagc tggtaagtca attctcttcc tattggaagc taatcctgga ccaggcctgg
      901 gaattctatt agcttatgct gtattcggta aaggttctgc taaatcttct tcttgggggg
      961 caatggttat tcatttcttc ggagggattc atgaaattta ctttccttat gttatgatga
     1021 agcctactct atttttagct gctatggcag gaggtatctc tggaactttt acttttcaac
     1081 tcttagacgc tggtcttaaa tctccagctt caccaggttc tattattgcg attatggcta
     1141 cggcgccaaa aggtgtttgg cctcatctaa atgttctttt aggtgtttta gtggcagcag
     1201 ttgtttcttt ccttgtagca gcccttattc ttcatgcaga caagtcaact gaggattcgc
     1261 tcgaagctgc tcaggcggct acccaagcag ctaaggctca gtctaaaggt cagttagtat
     1321 caacttctgt tgatgcagtt gtttcgacag actcagtgga aaaaatcatt ttcgcctgcg
     1381 atgctggtat gggaagctct gctatgggag ctagtattct tcgagataag gttaaaaaag
     1441 caggtctaga gattccagta tctaatcagg caatctcaaa tttgcttgat acaccaaaaa
     1501 cattaattgt tactcaggaa gaactgacac caagagctaa agacaagagt ccaagtgcta
     1561 ttcatgtttc tgttgataat ttcttagcgt cccctcgtta tgatgaaatt gtagcttcat
     1621 taacaggagc ttttccaata gcagaaattg aaggagatat accaacttca gcaccagtag
     1681 atagtcagga aattgacctt aaccatattg atgctgtagt agttgcttat ggtaaagcac
     1741 agggaactgc aactatgggc tgtgaaacga ttcgggctat ctttagaaac aagaatattc
     1801 gtattccagt ttctactgcc aaaatttcag aattaggtga atttaattct aaaaacataa
     1861 tgattgtaac aactatttct ttacaggcag aagtgcagca agcagcaccg aattctcaat
     1921 ttcttattgt ggatagttta gtaacaacac cagaatatga caaaatggct gctagaatgt
     1981 acaaatagaa ctagaggttt ctaaattacg aatgctatta accaaacgag aagaacaatt
     2041 attgaaggct ttcctacatg tagggaagct ttcaatgcaa gatatgactg aaatcttaca
     2101 ggtttcatct agaacaattt atcgaacttt atcagatttg acagatagca tggagcaata
     2161 tggaatcgaa ataacgaagc atgggaaata ctatattttg actggagagt tggatgattt
     2221 gccgacagaa cttgaagtgt tagttgagta tagtccccaa gaaagacaag agttgattac
     2281 ctatcgcctt ctgactgaga gtggttttgt caccaatgaa gcattgcaag agtgcacgaa
     2341 agtcagtaat gtaactatta ttcaggatat ttcagatatt gataagcgtc ttttagactt
     2401 tgatctgaaa attgaacgac aaaaaggtta tcggatttct ggtgattcag ttggtaagag
     2461 aagatttttg gctattttac tgacaaactg tatctcagta gcagattttt caaccggtaa
     2521 ttttgggagc tttgatattt tagaagcaga tagaactagg ctggccagtc agattgttaa
     2581 taagcaactg tcaggttttc cagatatgga tgctaggatg aagatgtttt ttgcgatctt
     2641 gttatctctt ataggtcagg agcaaaacat tgaaaattca cctaatacta gtaagcaggc
     2701 tttggaaatt tctcaaaaaa tttttcaaac ttactctaag cagactgcac aattttatag
     2761 tattcaggaa attatctatt ttgcgagcat cttggatgaa ttaatcatta aacgtcagga
     2821 caatccgctc tttacggaga aatttgatgg tgaatttttc tacaatattt caaatctgat
     2881 tgatacggtt tccatgtata ccaagattga cttttttaag gacaaggttt tattcaattt
     2941 tcttttccat catattcggc tcagtttagg agtccctatc ctttttcagg gtgaaaattt
     3001 gccagaatct gtccagattt tagttgaaag gaataaattt ctttatacag tcatcagtct
     3061 tttagtgaat gatatttttc cgaaatatct tcatacagag tatgagtatg gcatgattgc
     3121 cctacatttt atctctagct taggccgtag tccagagatt tatccagtcc gtgttttgct
     3181 tttaacggat gaacgtcggg tcactagaga tttattagtc agtaaaatta agagtgttgc
     3241 tccttttgta gagttgatag atattcagtc tctagtagat taccacagta ttgatctcag
     3301 tcagtatgat tatattttat ctaccaagcc gctgactaat caggaaatcg atgtaatttc
     3361 tagttttcca accgtcaaag aattgcttga attacaggaa cgacttcagt atgtacaggc
     3421 acatcgtaca attgtcgcgc gtgatgctat cgctccagag aaaagttatg acttgcaaga
     3481 ttatttaata tctagtagtc agcttttgag tcaattcgag ttggttcaat tggagaataa
     3541 tcaatcattt gagcacacgg tagaacaaat catccaatat cagaagaatg tgagtgacag
     3601 agattaccta acaagaaaat tgttatctca cttccagaat agtcctatgg ctattcctaa
     3661 tactggtctg gtgcttttac atagtcagtc tagcaaagta acaataaata gttttactat
     3721 gtttgaactc aaactaccta tctccgcatt gtcaatgaaa cgagaggaag aagaggtcaa
     3781 aaggtgtctg ctaatgctaa tgtctaaaga agctagcgag gaagcgagag atttaatgac
     3841 agctatcagt cagtcgatta ttgaaaatca tctttataca gagatttaca agacgggaaa
     3901 tcaatccatt atttatcaga tgctaaatac tatttttaac gaaaaaatta agaaattgga
     3961 gaactaatat gaaacttgaa aaacatttga ttaagcttaa taaacaattt tctaacaagg
     4021 aggaagctat ttgttattgt gggcaagttc tttatgagag tggatatgtt aatgaagact
     4081 atattgaagc catgattgag cgagataaag agctatctgt ttacatgggt aactttatcg
     4141 ccataccgca tggaacagat gcagcaaaaa atgatgtcct caagtctggt attacagtcg
     4201 ttcaagtccc tagaggggtt gattttggga atgtatctaa ccctcaagtg gcaacggttc
     4261 tttttggtat tgctggtatt ggtaatgaac acttagaaat tattcagaaa atttctatct
     4321 tctgtgcaga tgtagataat gttcttaaac tagcaggtgc tcagtcaaaa gaggaagtat
     4381 tgcgcttatt tgatgctgtt gaataattga atttcgtcat ttgtcatcta gtatatatgt
     4441 ccctcaaata ggaaaaggag aaattgaatg aaacattctg ttcattttgg tgccggtaat
     4501 atcggtcgtg gttttatagg tgaaattcta tttaaaaatg gtttccatat tgattttgtg
     4561 gatgtcaata atcagataat tcatgctcta aatgaaaagg gcaagtatga aattgaaatt
     4621 gcacagaaag gacagtctcg tatagaagta actaatgtgg ctggcattaa tagcaaagaa
     4681 catcctgagc aagtcattga agcgattcaa aagacggata ttattactac tgcaatcgga
     4741 cctaatatac tcccttttat cgccgaactt ctagccaaag gaatcgaagc tcgccgagtt
     4801 gcaggaaata cacaggcatt ggatgttatg gcctgtgaaa atatgattgg cgggtctcaa
     4861 tttctttatc aagaagtcaa gaaatattta agtccggaag gtttgacatt tgctgataac
     4921 tacataggtt ttccaaatgc tgcagtagac aggattgttc cagcacaaag tcacgaagat
     4981 tccctttttg ttgtggtcga gccctttaat gaatgggtcg tggaaaccaa gcgtcttaaa
     5041 aatccagatt tacgtctaaa agatgtgcat tatgaagaag atttagaacc ctttattgag
     5101 cgaaaacttt tttcagtcaa ttctggacat gcaacttcag cttacattgg tgcgcattat
     5161 ggtgccaaga caattttgga agctcttcaa aatcctaata tcaaatctcg gattgaatct
     5221 gtattagctg aaattcggag tctcttgatt gccaaatgga actttgataa aaaagaattg
     5281 gagaattatc acaaagtcat tatagaacgg tttaaaaacc ctttcatagc ggacgaggtt
     5341 agtcgcgtag ctcgcactcc aatccgaaaa ttaggctata atgaacgatt catccggccg
     5401 atacgtgaat tgaaagaact cagtttgtca tataaaaacc tacttaaaac agttggctat
     5461 gcctttgact atcgcgatgt aaatgatgaa gaaagtattc gattaggtga attgttggct
     5521 aaacaatcag tcaaagatgt tgttatacaa gttacaggtt tagacgacca agaattgatt
     5581 gagcaaattg tagagtatat ttaatctttt tcgaaaatct cttcaaatca ggttagcatc
     5641 gctttgtctt aggcatatgt tactgacttc gtcagttcta tctacaacct caaagcagtg
     5701 ctttgagctg actccgtcag tcttatctgc aacctcaaaa cactgtttga gttatctgcg
     5761 gtaatctttc tagcttgtct ttgatttttg ttgttattta taaggtaaaa gaagctggac
     5821 aaaaagtctt caaaatcgga aaaaggcagc ctatcgggtg ttcaaaaatc ttgataggat
     5881 gtcctttatt atggaaagcc ttattggatt ttctcctcag attgagtttt tgatcagctt
     5941 tatgagatag gttttgctag agatgtagcc catcatgtta tttttatgga cagtgggaaa
     6001 attgttgaaa aaaataatgc ccatcaattc tttagtcgtc caagagaaga acgaaccaag
     6061 caattttgga acgaattctt tcgaatgcga tctatatagt aaaatgaaac aagaacagga
     6121 caaatcgatc gggacagtca aatcgatttc taa
//
LOCUS       DAVMCN010000078         6147 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVMCN010000078 DAVMCN010000000
VERSION     DAVMCN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.079"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            170..370
                     /locus_tag="VYP85_001891"
     CDS             170..370
                     /locus_tag="VYP85_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882351.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="VYP85_001892"
     CDS             395..811
                     /locus_tag="VYP85_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882352.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="VYP85_001893"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="VYP85_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1882353.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILWDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLTLASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="VYP85_001894"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="VYP85_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1882354.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2691..4082
                     /locus_tag="VYP85_001895"
     CDS             2691..4082
                     /locus_tag="VYP85_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1882355.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4225..5142
                     /gene="adcAII"
                     /locus_tag="VYP85_001896"
     CDS             4225..5142
                     /gene="adcAII"
                     /locus_tag="VYP85_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1882356.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5150..>6147
                     /gene="phtD"
                     /locus_tag="VYP85_001897"
     CDS             5150..>6147
                     /gene="phtD"
                     /locus_tag="VYP85_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1882357.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEK"
BASE COUNT         1878 a         1119 c         1300 g         1850 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagc ctatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacgctt gaaagctttg gcaacagtat ctgatccaaa
      301 aatcgatgca acccaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagaataa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaattg atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacctaaa
      841 agacattttc gttcacaaaa gcagtgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttatgggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatgtcatg
     1321 ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggtgcttggc aaggagcgat ttatactctc
     1561 atttacactc tgggcatggc ccttcctttc ttggtcttga cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaatttc tgttggaaaa gatgctccag actttacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa cttagctttt
     2401 agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaagt gcacgacaaa
     2521 tagccctaaa acagagtcgt cttagagtaa cttccagttt tgggagagag atggaagtta
     2581 ttttgagaag ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat
     2641 ctcctatatt tatggtaaaa tagaattatc agtttatttt ggagtcaaag atgaatatat
     2701 ttagaacaaa gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg
     2761 atttgatttt gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta
     2821 ctgcagctgc aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt
     2881 gtgtgggatt atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag
     2941 gtgcctatag ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt
     3001 taaccatgat ggagttcatg acagccatat caggcgtagc ttcgggttgg gcagcttatt
     3061 ttaaaggctt gctctctcaa tatgggatag cccttcctca ggctttaaat ggtaccttta
     3121 atcctcaagc agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt
     3181 cgcttgtttt actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga
     3241 aattttccgc tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt
     3301 ggagcaattt tgctccttac ggctttggac aaatctatgg agctagtact ggtattatgg
     3361 ctggtgcgtc cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag
     3421 atgaagtcaa gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg
     3481 taaccattct ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt
     3541 taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca
     3601 actatgtgtc attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg
     3661 ccctatcgcg tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg
     3721 aactgacgaa gactagcaag gtaccaaaga atgctactat cttgacaggt ctagcttcag
     3781 cagtagcagc aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct
     3841 tagcctactt gatcatgctg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc
     3901 ccaaagctgg ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca
     3961 tttgtttatc cttcatgtta cagtataata tgaatacctg gattgctttc ctagttgcgt
     4021 tgttagtagg aagtattatt tacttcactt atggctataa gcattctacc atagaagaat
     4081 aaagtgaaag tctattgagt tgttgacact cagcagattt ttatatgtga aagaaatttc
     4141 aaattttttc taaaaatatc ttgacagatt aaattttcag gagtagaata tttactagtt
     4201 aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt
     4261 gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg aaaggggatg
     4321 aaaattgtga ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg
     4381 aatgatgttc ggatgattca gtcaagtagt ggtattcact cctttgaacc ttcggcaaat
     4441 gatatcgcag ccatctatga tgcagatgtc tttgtttacc attctcatac actcgaatct
     4501 tgggcaggaa gtctggatcc aaatctaaaa aaatccaaag tgaaggtctt agaggcttct
     4561 gagggaatga ccttggaacg tgtccctgga ctagaggatg tggaagcagg ggatggagtt
     4621 gatgaaaaaa cgctctatga ccctcacaca tggctagatc ctgaaaaagc tggagaagaa
     4681 gcccaaatta tcgctgataa actttcagag gtggatagtg agcataaaga gacttatcaa
     4741 aaaaatgcgc aagcctttat caaaaaagct caggaattga ctaagaaatt ccaaccaaaa
     4801 tttgaaaaag cgactcagaa aacatttgta acacaacata cagccttttc ttatctagcg
     4861 aagagatttg ggcttaatca acttggtatt gcaggtatct ctcctgaaca agaaccaagt
     4921 ccacgacaac taacagaaat tcaggaattt gttaagacct ataaggttaa aacgattttt
     4981 acagaaagta acgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt
     5041 cttaaaactc tgaatccttt agagtcagac ccacaaaatg acaagaccta tttagaaaat
     5101 cttgaagaaa atatgagtat tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa
     5161 taaaaaatat ctagcaggtt cagtggcagt ccttgcccta agtgtttgtt cctatgaact
     5221 tggacgttac caagctggtc aggataagaa agagtctaat cgagtttctt atatagatgg
     5281 tgatcaggct ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagagaggg
     5341 gatcaacgcc gaacaaattg ttatcaagat tacggatcaa ggttatgtga cctctcatgg
     5401 agaccattat cattactata atggcaaggt tccttatgat gccatcatca gtgaagaact
     5461 tctcatgaaa gatccgaatt atcagttgaa ggattcagac attgtcaatg aaatcaaggg
     5521 tggctatgtg attaaggtag acggaaaata ctatgtttac cttaaagatg cggcccatgc
     5581 ggacaatatt cggacaaaag aagagattaa acgtcagaag caggaacgca gtcataatca
     5641 caactcaaga gcagataatg ctgttgctgc agccagagcc caaggacgtt atacaacgga
     5701 tgatgggtat atcttcaatg catctgatat cattgaagat acgggcgatg cctatatcgt
     5761 tcctcacggc gaccattacc attacattcc taagaatgag ttatcagcta gcgagttagc
     5821 tgctgcccaa gcctattgga atgggaagca gggatctcgt ccttcttcaa gttctagtta
     5881 taatgcaaat acagctcaac caagattgtc agagaaccac aatctgactg tcactccaac
     5941 ttatcatcaa aatcaagggg aaaacatttc aagcctttta cgtgaattgt atgctaaacc
     6001 cttatcagaa cgccatgtgg aatctgatgg ccttgttttc gacccagcgc aaatcacaag
     6061 tcgaaccgcc aatggtgttg ctgtaccgca cggagaccat tatcacttta ttccttattc
     6121 acaactgtca cctttggaag aaaaatt
//
LOCUS       DAVMCN010000079         5835 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVMCN010000079 DAVMCN010000000
VERSION     DAVMCN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.080"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            77..1600
                     /locus_tag="VYP85_001898"
     CDS             77..1600
                     /locus_tag="VYP85_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016648332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882358.1"
                     /translation="MFSHILGFRLETNLRKRGIDGLEKASFRFFDLNPSGQIRKIIDD
                     NAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGIILLALTIIGGLILGAMMGE
                     QEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFKSFYKAIKDYSKYAYDYSLS
                     CKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLELIMILFLSGVLFVSFMRMM
                     WYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNYNIEFENVSFAYNDKAVIEN
                     LSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSIKIGGIAISEYSDEALIKAI
                     SFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGCDLILDKFPERENTIIGSKG
                     VYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEFELQKAFKNLMKDKTVIMIA
                     HRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSLQEMFNSANEWRVSNERVL"
     gene            1584..3305
                     /locus_tag="VYP85_001899"
     CDS             1584..3305
                     /locus_tag="VYP85_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882359.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3316..3900
                     /locus_tag="VYP85_001900"
     CDS             3316..3900
                     /locus_tag="VYP85_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1882360.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            3900..4595
                     /locus_tag="VYP85_001901"
     CDS             3900..4595
                     /locus_tag="VYP85_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1882361.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            4583..>5835
                     /locus_tag="VYP85_001902"
     CDS             4583..>5835
                     /locus_tag="VYP85_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882362.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKVEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNM"
BASE COUNT         2107 a          758 c         1110 g         1860 t
ORIGIN      
        1 atccggtgca gagagtatag cattaaaatc tgttattaca ctaacaagtg gagcgatatt
       61 ttattttgtc tcaggaatgt tttcacatat cttgggattt aggcttgaaa caaatttaag
      121 aaaaagggga atcgatggtc tggaaaaagc aagttttagg ttctttgact taaatccatc
      181 tggtcaaata agaaagatca tagatgataa tgcagcacaa actcatcagg tggtagcaca
      241 catgattccc gatagttctc aggcaataat cacacccgta cttgtacttg cacttggctt
      301 tatagtaagt ataagggttg gcataatttt gcttgctctt actataattg gtggcttaat
      361 tttaggggca atgatgggcg agcaagaatt tatgaagata taccaagaat ccctatctaa
      421 actaagtgct gaaactgttg agtacgtgag aggaatgcaa gttgtaaaaa tatttaaagc
      481 aaatgtagag tcttttaaaa gcttttataa ggcgataaaa gattactcaa agtatgctta
      541 tgattattcc ctatcttgta aaaggcctta tgttttgtat caatggttat tttttggact
      601 gattgcaatt ttaattattc ctatagttta ttttatgact agcttagcta gcgcaaaggt
      661 gattttactt gagcttatca tgattttatt tttatcagga gttctctttg tttcattcat
      721 gagaatgatg tggtactcca tgtatatttc tcaaggaaat tatgcagtag atactttaga
      781 ggcgctttac gaagatatgc aaaaagacaa attagtgcat ggtaatgtca ataattttaa
      841 aaactataat atagaatttg agaatgttag ctttgcttat aatgataaag ctgtcattga
      901 aaatttatcc tttaatttag aagaaggaaa gtcctacgca cttgtcggtt catctggatc
      961 aggcaaatca acagtagcaa aacttatatc aggtttttac aatgttaata aaggaagcat
     1021 aaagataggc gggatagcaa taagtgaata ttctgacgaa gccttaatta aagccatttc
     1081 ctttgttttt caagattcaa aattattcaa gaagagcatt tatgataatg tagctttagc
     1141 taataaagat gcgacgaaag atgacgttat gagagcctta aaattagcag gatgcgattt
     1201 aatattagac aaattcccag aaagagaaaa tacaatcata ggctcaaaag gtgtttattt
     1261 atccggtgga gaaaaacaaa gaattgcaat tgctagagca attttaaagg attccaaaat
     1321 tattattatg gatgaagcat cagcatctat tgacccagat aacgagtttg aattgcaaaa
     1381 agcttttaaa aatcttatga aggataaaac agttatcatg attgcacaca ggctatctac
     1441 aattaaagac cttgatgaaa ttattgtcat ggatagtgga aaaattatag aaagagggtc
     1501 tgacaaagaa ttaatgtcaa aagatacaag gtataagagc ctgcaagaga tgtttaacag
     1561 tgcgaatgaa tggagggttt caaatgaaag agttttataa aaaaagattt gctcttacag
     1621 atggaggagc aagaaattta agtaaagcaa cactggcttc atttttcgtt tattgtataa
     1681 acatgcttcc tgccatatta cttatgattt ttgctcagga agttttggaa aatatgggca
     1741 aaagcaatgg cttttatata gtattctcag ttttgacttt gatagcaatg tatattttgc
     1801 tttctatcga atacgataaa ttatataaca caacctatca agaaagtgca gatttaagaa
     1861 taaggacagc ggagaattta tcaaaattac ctctatctta cttttctaaa catgacattt
     1921 ccgacatttc acaaacaatc atggctgata ttgaaggcat agagcatgca atgagccact
     1981 caataccaaa ggtgggcggc atggtactgt ttttcccatt aatatctgta atgatgctag
     2041 cgggcaatgt caagatgggt ttagctgtaa ttattccatc tattttaagc tttatattta
     2101 tacctttatc taaaaaatat caggttaatg gacagaatag atattatgat gtcttaagaa
     2161 aaaactcaga aagctttcaa gaaaatatcg aaatgcaaat ggagattaaa gcatataatt
     2221 tatcgaagga tattaaagat gacttatata aaaaaatgga agatagtgag agagtacact
     2281 taaaggcgga agtaactaca attttaactt tgtctatatc ttcaatattt agctttatat
     2341 ctcttgctgt tgtgatattt gtcggcgtaa atctaattat taataaagag ataaattctc
     2401 tctaccttat aggatattta ctagctgcta tgaagataaa agactcttta gatgcatcta
     2461 aagagggctt gatggaaata ttttatttat cgcccaaaat agaaagatta aaagaaattc
     2521 aaaatcaaga tctacaagaa ggcgatgact atagcttaaa aaaatttgat attgatctaa
     2581 aagatgttga gtttgcctac aataaagacg caaaagtttt aaatggtgta agttttaaag
     2641 ctaagcaggg agaggtcact gctttggtag gtgcaagtgg ctgcggtaaa acaactatct
     2701 tgaaacttat atcaagactt tatgattatg acaagggaca aatcttaatc gatggcaaag
     2761 atataaaaga aatatcaaca gaatctcttt ttgataaggt ctctatagtt ttccaagatg
     2821 tggttctctt taatcaaagc gttatggaaa atattagaat cggaaagcaa gatgcaagtg
     2881 acgaagaggt taaaagagca gcaaaacttg caaattgcac agattttata gaaaaaatgg
     2941 ataaaggttt cgatacagtt attggtgaga acggagctga gctatcagga ggagaaagac
     3001 aaagattatc aatagccaga gccttcttaa aagatgcgcc gatattgatc ttagatgaga
     3061 taacagcaag ccttgatgtt aacaacgaga aaaagattca agagtcttta aataatttag
     3121 ttaaagataa aactgttgta atcatttcac atagaatgaa atccatagaa aatgcagaca
     3181 agatagtagt tcttcaaaac ggaagagtag aaagcgaagg taagcatgaa gagcttttac
     3241 aaaaatcaaa aatttacaaa aatttaatag aaaagacaaa aatggcagaa gaatttattt
     3301 attaggagga ctacaatgga taataaaaaa ttaaaagtaa aagatttagt aagcatcggt
     3361 gtttttggcg taatttattt tgccttcatg tttggagttg gtatgatggg cttgattcca
     3421 atattgttct taatataccc gacagtatta gccatagttg caggaactgt tgttatgtta
     3481 tttatggcta aggttcaaaa gccatgggca ctatttatat ttggtatgat atcaccactt
     3541 gtgatgtttg cagctggtca tacctacgta gttgtggttt tatcacttat agtaatgata
     3601 atagcagaat taattagaaa gattggtaat tataattcat ttaaatacaa tatgctttct
     3661 tatgcaatct tcagcacatg gatatgtagc tctttaatgc aaatgctttt agcaaaagaa
     3721 aaatatatgg agtggtcttt gatgacgatg ggaaaagatt atgttgatgt attagaaaag
     3781 ttaataactt atcctcacat ggctttagta gccttaggtg ctttcttagg aggaattctt
     3841 ggagcatata taggcaaggc tctattgaaa aaacactttg aaaaagcagg cattgtataa
     3901 tgcctacttt ttcttcaaat gctcccttta atcccaatcc gatctctaag atattagtcg
     3961 tatttatcac aggcttaact gttatgcata gcataaacat ccgttttgag ctggcaattg
     4021 tttgtcttat tggtattttg ctttatttga atggatacaa aaaaacactt ttcaaatgga
     4081 ttatattgtg tgggatactt tactccttgc ctaattttat ggtgttatct gaattaaacc
     4141 ctatagttaa gatgtttttg agtataccta ttgttattag aatgtttatt ttaccattta
     4201 tggcagcaag ctttatgata aagacctcgg atgtaggcgc aataatttca tcgatggata
     4261 agcttaagat ttcaaagaat gtatccatac ctattgcggt tatgtttaga ttcttcccat
     4321 cttttaagga ggagaagaaa aacatcaaaa tggctatgag agtaagaggg ataaatttta
     4381 aaaacccagt caaatatctt gaatatgttt ctgtgccact actcattata tcatctaata
     4441 tatcagatga cattgcaaaa gcggcagaaa caaaggcaat agaaaatcca attgccaaga
     4501 ccagatacat tcgcgtaaag atacagctaa ttgattttgt ttatgtttta gcggttgttg
     4561 gacttattgt gggaggctta atatggttga aataaaaaat ttaagtcttg attatggtga
     4621 agagcatata ttagatgata tatcactatc catagccgag ggagagtgcg tgctatttac
     4681 aggaaaaagt ggaaatggta agtcatcttt aataaattca atcaatggac tagctgtaag
     4741 gtatgataac gcaaagacaa aggtcgaaat aattattgat ggtaagaata taaaaaattt
     4801 ggaactttat caaatctcaa tgcttgtttc aactgttttt caaaatccta agacatattt
     4861 ttttaatgtc aatacgacat tagaattatt attttatttg gaaaatatcg gtcttgcaag
     4921 agaagagatg gacaggcgtt tgaaggatat gcttgagata ttcccgataa aaaatctttt
     4981 gaacagaaat atatttaatc tatccggcgg tgaaaaacaa attctttgca ttgcagcttc
     5041 ttatatagca ggtacaaaga ttatagttat ggatgagcct tcatcgaatt tagatattaa
     5101 aagcataagt gttttggcaa agatgctaaa gatattaaaa gagaaaggca taagcataat
     5161 tgttgcagag catagaattt attatttgat ggacatagtt gaccgtgtat ttttaataga
     5221 taaaggaaag cttaaaaaaa cttatactag aagtgaattt ttaaagctag ataaaaatga
     5281 attaaatgct ttaagtttaa gagataaaga attaagtaaa ttaaaagttc cttatttaaa
     5341 agaaggtgga gagtatcaga taaaaaatct tagctacaaa tttactgatg atgagtgttt
     5401 aagcttaaaa gatatttcgt tcaagcttgg gaaaatttat ggcataatag gatccaacgg
     5461 acgaggaaaa tcaacgcttt taagatgttt aataggtctt gagaaaaaat caaaagaaga
     5521 aatttatttt aagggagaga agctatctaa aaaagaaaga ctcaaaaact cttcacttgt
     5581 tatgcaagat gtaaatcatc aattattcac agatgaagta ttcaacgagc ttagattagg
     5641 agtaaagaat tttgatgaag aaaaggcgaa aatcatttta aaagatttag gcctggacga
     5701 atttattgaa aggcatccga tgagtttatc aggagggcaa aagcaaaggc ttgcaatagc
     5761 atctgttatg tgcaagaatt ctccatttgt cttttttgac gaaccttcaa gtggtatgga
     5821 ttattccaat atgat
//
LOCUS       DAVMCN010000080         5606 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVMCN010000080 DAVMCN010000000
VERSION     DAVMCN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.081"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..186
                     /locus_tag="VYP85_001903"
     CDS             <1..186
                     /locus_tag="VYP85_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882363.1"
                     /translation="KYSVDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNK
                     DNEYREMMKNKKMDQER"
     gene            260..433
                     /locus_tag="VYP85_001904"
     CDS             260..433
                     /locus_tag="VYP85_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882364.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            619..1146
                     /locus_tag="VYP85_001905"
     CDS             619..1146
                     /locus_tag="VYP85_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV1882365.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1273..2001
                     /locus_tag="VYP85_001906"
     CDS             1273..2001
                     /locus_tag="VYP85_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1882366.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            2685..2846
                     /locus_tag="VYP85_001907"
     CDS             2685..2846
                     /locus_tag="VYP85_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882367.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            2938..4617
                     /locus_tag="VYP85_001908"
     CDS             2938..4617
                     /locus_tag="VYP85_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1882368.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSRIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            4885..5451
                     /locus_tag="VYP85_001909"
     CDS             4885..5451
                     /locus_tag="VYP85_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882369.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         2384 a          719 c         1091 g         1412 t
ORIGIN      
        1 aaatattcag tagattttgt aaacaaagaa cttggtatag atttatccat agaaatagat
       61 aagctaataa aacagggaga aaaaccaagt gtaatagcac agattaaaaa gttccaagac
      121 caagtcaata aagataatga atacagagaa atgatgaaaa acaagaaaat ggatcaagaa
      181 agataagacc tggtaaaaat atcttatcca agctataata tgaccaaaca actaaagtca
      241 gatctaggag gtaatagaga tgaataaaag gcaagagcta atagatgaac tcataaaagc
      301 aaatgaagat ggaacataca aaacctataa aagcacagaa gaaataaaag caatgaacaa
      361 tgaagaaata cagattatat attctaacat gaaaaactat ctatcagaca aaagaacaca
      421 cataaactat taaaggtgga aaggtagtgt aagctatttt taaaagtata aaaggtacaa
      481 agacctaaga aatatataaa aacatcaaaa taaagtattc caccaccaag aacaataaaa
      541 taaaaacaag caaagggaag tatagaaaaa ttaaaaccta tacttccctt ttttaattca
      601 aacaaaggag agaaaagcat gataaacgaa gaaataagca aggaagcagg tcaagcagca
      661 caaaccataa tatcatacac aataaaggca acaaaagaat caatcaattt agaaaaagaa
      721 ataagaaaaa agatgaatga aactttagaa aaagcaaatg gaaacttaaa aagtcttatg
      781 ggcgatgaaa tgaaaataaa agacctctac aagaaaggac aactagaaaa tataagcata
      841 gatcaaatcg acctcaaaga cttaaaaaaa gaactaaaca aacttggagt aagtttctca
      901 gtaatgaaaa acaaagaaag caaaaactat gaaatattct tccaagccaa agacataaaa
      961 gtaatggaat atgcctttaa gcaagtcata gccaaggaaa ataaaaaaga aaaagaaagt
     1021 atcctaaaac aaataaagaa atacaaagac ctatccaaaa acaaagataa gacaaaagaa
     1081 aaaggaaaaa ggaaagtaaa agaaaaagta aaaccaaaca aaaaagatat gaccagagaa
     1141 atctaaaggg agtaacgaaa agttacaccc ttaaataacc ataataacaa gacttccgaa
     1201 aaacagaagt ccagaattcc gaaaatcgga aatcaagaat ttcgattatc gaaaatcaag
     1261 aaaggagcag atatggcaac aaacaaaaga tactattgga taaaattaaa agaagaattt
     1321 ttcacagaca aaaggataaa aaggttaagg agaatatctg gaggagatac ctatacgata
     1381 atctacctaa aacttctact actaagccta aaagatgagg gcaaactcta ttatgacgga
     1441 gtagaaagtg attttataaa agagttagca ctaaccatag atgaaacaga cgatgatgta
     1501 atggtaacag taaattattt aatcaatcaa ggcttattag aagttgtaac agaaaatgat
     1561 gaatactacc taactgaaat accaaactta atcggatcag aaacagcctg ggcagagaaa
     1621 aaaagaagat acagacaaaa taaacagagg acattgtcct taatgagtcc aacccatgtc
     1681 cgacaagaga tagagataga gaaagatata gagatagata aagagagaga gggagagata
     1741 gataaaaagt ccacccccat tttttatgga gaattcaaaa atgtaaggtt aagcaaagaa
     1801 gaatataaaa atctaaaaga aaaattaaac tcacacacag atataatgat aaataaacta
     1861 tccagataca tggaaagcag tggtaagacc tatcaaaacc actatgtgac aatcttaaaa
     1921 tggtatgaag aagataaaga caaactaaga cagaaaggtt taaataaaaa aatgaattat
     1981 gatgtaggag aatctttata gataaaaaga ggtggaaagg cactattaaa gactttaagt
     2041 ttaaaaaggt atcaaagtat gccagagata aaaaaatata aatatgacac tttaaaggcg
     2101 attagaaaat taaagaaatg ctagaagact tttagatgac agttaccaag agggtctaat
     2161 tttcactgct acttatgcag taggaattgg acctttttat ataagcaaat tctatttcaa
     2221 aattggttac caagaaagac ttcttttcac tgttaagtat aagagggtaa tttatagaat
     2281 tttgttacat caagataaat attttctgat ggtcaaattt taaaaagatt aataactctc
     2341 gataaatttt gaaccttaac aattgaatag accaagacaa gacgttaatt atttttggag
     2401 cgtaataacc tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa agttctgcta
     2461 agcaaaaaga aagtgagcga taagtaagag tttgaatata gggagggata ccctatccgc
     2521 tatgaagaaa atgaggataa tgatacttct aaggttgaag caggctcatc cggaatagag
     2581 gcggaggtga gattcctatg ttgctaatcc aaagcacttg tcaatgtcaa aaaacttaat
     2641 taaacaaata attattagat ataaaacttt agaggaggta tatattggac aatgactgga
     2701 atggattggc tgatttaata gcaaatctga ttgcaaaata tgctggtgct ttagatttag
     2761 ataatctacc cgatccaacg ccagcaaaaa atcaagagat gaaaaatagt tttgacatgg
     2821 caaaaacaca aattgagacg gactaataaa agtgttataa tatacttgaa atgatagtcc
     2881 aaacttaaat taaaaaaatt atatatgata tagaaaaatt atattgaggt taatactatg
     2941 tcaaaagaaa aaataaaagt atacctctat acacgagtat ctacgtcaat acagatagag
     3001 gggtattcgt tagaggcaca aaaatcacga atgaaagctt ttgctattta caatgattat
     3061 gaaattgttg gagaatatga agatgccggg aagtctggca agtctattga aggtagaata
     3121 cagttcaatc gaatgatgga agatataaaa tctggaaaag atggagtatc ttttgttctt
     3181 gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg ttctttctac acttcagata
     3241 atgcaggatt atggagttaa tcttatctgc gttgaagatg gcattgattc atctaaagat
     3301 gctgggaaac taatgatttc tgttttatca gctgtggctg aaatagaaag agaaaacatc
     3361 cgtattcaaa caatggaagg tcgcattcaa aaagcaaggg aaggaaaatg gaatggtggc
     3421 tttgctccgt atggatataa acttgaagac ggcaagctgt ttataaatga ggaagaggca
     3481 gttgcaataa gaacgatttt cgaccagtat gtaaatacta cgataggagc caatgggata
     3541 tctaaatact tagagaatca tggaattaga aaaatcccaa gacagaatgg taagaatcct
     3601 ttgtttgatg caggtcttat aagaaagata ttaaagaatc ctgtatataa tgggaaaata
     3661 gcatttggaa gaagaacttt agaaaaagtt catggtacaa gaaatgaata taagcaggtt
     3721 gaacaagatg aatatctaat atctgaaggg atacatgaag ctatagtttc cgatgaagtt
     3781 tggcaagctg ctcaggttaa gctaaaatct caagcaaaga aatatgagca tgtgaataaa
     3841 ggaaaagata cacgcacaca cttgctttct agaattgtaa aatgcccgat atgtggagtg
     3901 ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg gcacaaagta taaagatttt
     3961 tattactatg gttataaaca taggcagatg ataagaggtc ataagtgtac attcagtaag
     4021 caaattagag aagaattgtt agatgatgct gttgcagagg tgattgtcaa gatagtaagt
     4081 aatccgaaat ttgcttctat gatgcaagaa aaaatcaaca tgaaggtgga tacctctgaa
     4141 atagaaaaag aaatagataa ttaccaaaag gaattgagaa agagtcattc tacaaagttt
     4201 aagctaattg aggaaataga taatttagat gttgaagata agcattataa gagaaggaaa
     4261 caggatttag atgatagact atatcgtatg tatgacaaaa tagatgaatt agaatcatca
     4321 ctaattgatg cgaaagcaaa gaaacagact attgaagctg aaaagcttac aggagataac
     4381 atatataagg ttctgatcta ttttgataag ctctataaag tcatgaatga tgtagagcgt
     4441 aggcagttaa tttcagcttt gatttctgaa attcaagttt atgaagaaaa acaatctaac
     4501 ggacaatggc taaaatccat tacttttaag ctaccaatta tagaagaaaa tctcaacata
     4561 ggtttggata atgatgaaca agttgaatgt gtaagtttat tagagaaacg tagttaatcc
     4621 tcaaaaggtt ccccaaacct tttgagtccc actgacgcat cacgctgagg cggtatcact
     4681 gcttgtacga gttgaagcat cagcgaagta aaagtagatg ttcagccaat gcgacgaggt
     4741 gagaccgaag gtcgataagg tgtgttctgg gtataggact cgtaaagtaa gtaggaaata
     4801 tgatgagatg atacagagag cctgaattgg tcaggtgacg tgcttattta cattagcctg
     4861 ataatgaaaa tggagagatt atcgatggtt atattggaat tgtaccaaaa tgattattct
     4921 aaagatttag tagcatttga ttccatagaa gatgggaaag cctttgtagc tcaaatcccg
     4981 ggatacactc tggaaacaga agatggtttt gaagtggagt attttaatcc taaaaacata
     5041 ccggattata tggaaattat ttttaacgga aatattgttc ctttatctaa atttatgttc
     5101 gatcctgagg aaaatgtaaa cattatttgg aaagagattt caaatttatc cctcaaaaat
     5161 gatagagtga tcgaaggata ttcaaaaatt gatgcatatg tcgttaacaa ccatgaagtt
     5221 aaagcctatg tcgaaacaag agaaacgaac tatcgtaaag caaaagactt cttagaaagc
     5281 cgcggatatg aaatcgacag aagctttttc ggaagtgaag acggtgaagc gattctttac
     5341 agaaaaaaag ggatcgaagt ttggcatttc ttgtgtcact tagacccaat gtttgtagag
     5401 attgaagatg tagaaggata tgttaaagaa gaagttggag agattcaata gtcaaccaaa
     5461 gttccttgtg agtatatacc tttgctagta aaagagtcaa aacgttataa cgaagggggg
     5521 aagaaaaccc ttgagtgtaa gtctttttct tgtttagagg gaaagtatta gagtagccgc
     5581 tcataattta tactagattt gataac
//
LOCUS       DAVMCN010000081         5293 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVMCN010000081 DAVMCN010000000
VERSION     DAVMCN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.082"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            963..2222
                     /locus_tag="VYP85_001910"
     CDS             963..2222
                     /locus_tag="VYP85_001910"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1882370.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2238..2789
                     /locus_tag="VYP85_001911"
     CDS             2238..2789
                     /locus_tag="VYP85_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882371.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2782..4059
                     /locus_tag="VYP85_001912"
     CDS             2782..4059
                     /locus_tag="VYP85_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1882372.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4075..4935
                     /locus_tag="VYP85_001913"
     CDS             4075..4935
                     /locus_tag="VYP85_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1882373.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAIMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         1600 a          858 c         1202 g         1633 t
ORIGIN      
        1 tgtactattc tagtttcaat caactatatt gttataaatt gatttgaatt tcaaaattaa
       61 attgtttgat tcttatttca atttgttata gtatatctga tgtcaaagtt ctcggcgagt
      121 caaatagcga ttcccaagcc tgactatcgt gaggtagcag attaaaatgg tctggggata
      181 gaccgtttta agtctgacgc tggaaataag aattgtcaga agaagggata gcgaaatcgt
      241 ggctctacga acaggaacgt gataataagg cgtatatagc ggataagggg gtctcaaact
      301 ctaaagtcca aaaaggtagt cgtaacctat atgcgtaaat cacgagagta attgaattcg
      361 tactaagatt ttctattttc actgtaacct tttaacgtcc ttatatcttg tatacacgag
      421 gaaagatgta cgacttatcc cgtgaggtct atcactataa agagaaaacg acagatagaa
      481 gtgatcctga gtcacggtta tctgtctgat aggacggtat gtataaaacg cttctgtgaa
      541 ctgagagaag ggggagaagt tcttgctaaa atttagttga acagccgtat tccgatactt
      601 agataagaga tctagtctta gctcctactc agttttaggg gataaaaaag gggcaatagc
      661 gattcgagaa agattatact cttcgaaaat ctcttcaaat cacgtcaata tcgccttgtc
      721 gtatgtgtag gatactgact acgtcagttc catctacaac ctcaaaacag tgttttgagc
      781 aacctgcggc tagtttccta gtttgatctt tgattttcat tgagtattag taattcagtt
      841 actaactcgt caactctgat ttatccaata aaattgaaaa ggatggaaaa aaggataaat
      901 ttatgatata ctttattttg aagaccttat tagaaatctt gaaagagtat tgaaaactta
      961 gaatgagaaa aattgttatc aatggtggat taccactgca aggtgaaatc actattagtg
     1021 gtgctaaaaa tagtgtcgtt gccttaattc cagctattat cttggctgat gatgtggtga
     1081 ctttggattg cgttccagat atttcggatg tagccagtct tgtcgaaatc atggaattga
     1141 tgggagctac tgttaagcgt tatgacgatg tattggagat tgacccaaga ggtgttcaaa
     1201 atattccaat gccttatggt aaaattaaca gtcttcgtgc atcttactat ttttatggga
     1261 gcctcttagg ccgttttggt gaagcgacag ttggtctacc gggaggatgt gatcttggtc
     1321 ctcgtccgat tgacttacac cttaaggcgt ttgaagctat gggtgccact gctagctacg
     1381 agggagataa catgaagtta tctgctaaag atacaggact tcatggtgca agtatttaca
     1441 tggatacggt tagtgtggga gcaacgatta atacgatgat tgctgcggtt aaagcaaatg
     1501 gtcgtactat tattgaaaat gcagcccgtg aacctgagat tattgatgta gctactctct
     1561 tgaataatat gggtgcccat atccgtgggg caggaactaa tatcatcatt attgatggtg
     1621 ttgaaagatt acatgggaca cgtcatcagg tgattccaga ccgcattgaa gctggaacat
     1681 atatatcttt agctgctgca gttggtaaag gaattcgtat aaataatgtt ctttacgaac
     1741 acctggaagg gtttattgct aagttggaag aaatgggagt gagaatgact gtatctgaag
     1801 acagcatttt tgtcgaggaa cagtctaatt tgaaagcaat caatattaag acagctcctt
     1861 acccaggctt tgcaactgat ttgcaacaac cgcttacccc tcttttacta agagcgaatg
     1921 gtcgtggtac aattgtcgat acgatttacg aaaaacgtgt aaatcatgtt tttgaactag
     1981 caaagatgga tgcggatatt tcgacaacaa atggtcatat tttgtacacg ggtggacgtg
     2041 atttacgtgg ggccagtgtt aaagcgaccg acttaagagc tggggctgca ctagtcattg
     2101 ctgggcttat ggctgaaggt aaaactgaaa ttaccaatat cgagtttatc ttacgtggtt
     2161 attctgatat tatcgaaaaa ttacgtaatt taggagcgga tattagactt gttgaggatt
     2221 aaaccgtaga ggtgtttatg aatatttgga ccaaattagc aatgttttct ttttttgaaa
     2281 cggatcgctt gtatttgcgt cctttctttt ttagtgatag tcaggacttc cgcgagatag
     2341 cttcaaatcc agaaaatctt caatttattt tcccaacgca ggcaagtctg gaagaaagtc
     2401 aatatgcact ggccaattac tttatgaagt cccctttggg agtgtgggca atttgtgacc
     2461 agaaaaatca acaaatgatt ggttctatta aatttgagaa gttagatgaa atcaaaaaag
     2521 aagctgagct tggctatttt ttgagaaaag atgcttggtc gcaaggattt atgacagagg
     2581 ttgttagaaa aatttgtcag ctttcttttg aggaatttgg cttaaaacaa ttatttatca
     2641 ttacccacct tgaaaataaa gctagccaaa gagttgctct taagtctgga tttagtttgt
     2701 tccgtcagtt taagggaagt gatcgttaca caagaaaaat gcgggattat cttgaatttc
     2761 ggtatgtaaa aggagagttc aatgagtaag catcaggaaa ttctaagcta tttggaggaa
     2821 ttaccagtag gtaaaagggt cagtgttcgt agcatttcga atcatctagg agttagtgat
     2881 ggaacagcct atcgggctat taaagaagct gaaaaccgtg gaattgtgga gacccgtcct
     2941 agaagtggaa caattcgtgt taaatcccag aaagttgcta tagagagatt aacgtttgct
     3001 gaaattgcag aagtgacttc ttctgaggtt ctggctgggc aagaaggttt agagagagag
     3061 tttagtaagt tttcaattgg tgccatgact gaacaaaata tcttgtctta ccttcatgat
     3121 ggggggctct tgattgtcgg agaccgaacc cgtattcagt tgctagcctt ggaaaatgaa
     3181 aatgcagttc tggttacagg gggatttcag gttcatgatg atgtgcttaa actggccaat
     3241 caaaaaggga ttcctgttct aagaagtaag catgatacct ttaccgtcgc gaccatgatc
     3301 aataaagcct tgtcaaatgt ccaaatcaag actgatattc tgacagttga gaaactttat
     3361 cgccctagtc atgagtatgg ttttctaaga gagacagata cagttaaaga ttatttggac
     3421 ttggttcgta agaatcgtag cagccgtttc cctgttatca atcaacatca ggtcgttgtt
     3481 ggtgttgtaa ccatgagaga cgctggtgat aaatcaccaa gcacgacaat tgataaggtt
     3541 atgtctcgta gtctattttt ggttggatta tcgacaaata ttgccaatgt gagtcaacgg
     3601 atgatcgcag aagactttga aatggtacca gttgttcgaa gcaatcaaac tttgcttggc
     3661 gttgtgacgc gacgagatgt catggagaag atgagccgtt cccaagtttc ggctctacca
     3721 actttttctg agcagattgg acaaaagctc tcttatcacc atgatgaagt agtcattaca
     3781 gtggaaccct ttatgctaga aaaaaatgga gttttggcta atggtgtatt ggcagaaatt
     3841 ctgacccaca tgacccaaga tttagttgtt aatagtggtc gcaatctcat tatcgagcag
     3901 atgctgatct actttttgca ggctgttcag atagatgata tattgcgcat tcaggcacgg
     3961 attattcatc atacgagacg gtcagctata attgattacg atatttatca tggtcaccag
     4021 attgtttcaa aagcaaatgt gactgttaaa attaattaga aactaggaga aaagatgata
     4081 acattaaaat cagctcgtga aatcgaagct atggacaagg ctggtgattt tctagcaagt
     4141 attcatatag gcttacgtga tttgattaag ccaggcgtag atatgtggga agttgaagaa
     4201 tatgtccgcc gtcgttgtaa agaagaaaat ttccttccac ttcagattgg ggttgacggt
     4261 gccataatgg actatcctta tgctacctgt tgctctctta acgatgaagt ggctcacgct
     4321 ttccctcgtc attatatctt gaaagatggt gatttgctca aagttgatat ggttttggga
     4381 ggtcccattg ctaaatctga cctaaatgtc tcaaaattaa acttcaacaa tgttgaacaa
     4441 atgaaaaaat acactcagag ctattctggt ggtttagcag actcatgttg ggcttatgct
     4501 gttggtacac cgtccgaaga agtcaaaaac ttgatggatg taaccaaaga agctatgtac
     4561 aagggtattg agcaagctgt tgttggaaat cgtatcggtg atatcggtgc ggctattcaa
     4621 gaatacgctg aaagtcgtgg ttacggtgta gtgcgtgatt tggttggtca tggtgttggc
     4681 ccaactatgc acgaagaacc aatggttcct aactatggta ttgcaggtcg tggactccgt
     4741 cttcgtgaag gaatggtctt aaccattgaa ccaatgatca atacaggcga ttgggaaatt
     4801 gatacagata tgaaaactgg ttgggcgcat aagaccattg acggtggatt gtcatgtcag
     4861 tatgaacacc aatttgtcat tacgaaagat ggacctgtta tcttgactag ccaaggtgaa
     4921 gaaggaactt attaataaaa agtgaaaaga ctactggaag tttattttga taaaaaatcc
     4981 agtagatctt ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt
     5041 tttctgcttt taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag
     5101 gattcagggc tctcctccta tatactatta gtaaagtaaa actaagagag gatattttag
     5161 tgtcgcagtc tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga
     5221 gaaatggaat tctgtttaac gttcgtattg ccaatcttaa atttaccttt tttagattag
     5281 acttcctgcg aaa
//
LOCUS       DAVMCN010000082         5115 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVMCN010000082 DAVMCN010000000
VERSION     DAVMCN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.083"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            212..1757
                     /locus_tag="VYP85_001914"
     rRNA            212..1757
                     /locus_tag="VYP85_001914"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1809..1881
                     /locus_tag="VYP85_001915"
     tRNA            1809..1881
                     /locus_tag="VYP85_001915"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1842..1844,aa:Ala,seq:tgc)
     gene            2006..4907
                     /locus_tag="VYP85_001916"
     rRNA            2006..4907
                     /locus_tag="VYP85_001916"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4984..5099
                     /gene="rrf"
                     /locus_tag="VYP85_001917"
     rRNA            4984..5099
                     /gene="rrf"
                     /locus_tag="VYP85_001917"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1447 a         1037 c         1499 g         1132 t
ORIGIN      
        1 aaaaagctta aaaatcttca aaaaagtgtt gacaagcgaa agcggctgtg atatactaat
       61 atagttgtcg cttgagagaa gcaagtgaca aagacctttg aaaactgaac aagacgaacc
      121 aatgtgcagg gcgctacaac ataagttgta gtactgaaca atgaaaaaac aataaatctg
      181 tcagtgacag aaatgagtaa gaactcaaac ttttaatgag agtttgatcc tggctcagga
      241 cgaacgctgg cggcgtgcct aatacatgca agtagaacgc tgaaggagga gcttgcttct
      301 ctggatgagt tgcgaacggg tgagtaacgc gtaggtaacc tgcctggtag cgggggataa
      361 ctattggaaa cgatagctaa taccgcataa gagtggatgt tgcatgacat ttgcttaaaa
      421 ggtgcacttg catcactacc agatggacct gcgttgtatt agctagttgg tggggtaacg
      481 gctcaccaag gcgacgatac atagccgacc tgagagggtg atcggccaca ctgggactga
      541 gacacggccc agactcctac gggaggcagc agtagggaat cttcggcaat ggacggaagt
      601 ctgaccgagc aacgccgcgt gagtgaagaa ggttttcgga tcgtaaagct ctgttgtaag
      661 agaagaacga gtgtgagagt ggaaagttca cactgtgacg gtatcttacc agaaagggac
      721 ggctaactac gtgccagcag ccgcggtaat acgtaggtcc cgagcgttgt ccggatttat
      781 tgggcgtaaa gcgagcgcag gcggttagat aagtctgaag ttaaaggctg tggcttaacc
      841 atagtaggct ttggaaactg tttaacttga gtgcaagagg ggagagtgga attccatgtg
      901 tagcggtgaa atgcgtagat atatggagga acaccggtgg cgaaagcggc tctctggctt
      961 gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag gattagatac cctggtagtc
     1021 cacgctgtaa acgatgagtg ctaggtgtta gaccctttcc ggggtttagt gccgtagcta
     1081 acgcattaag cactccgcct ggggagtacg accgcaaggt tgaaactcaa aggaattgac
     1141 gggggcccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga agaaccttac
     1201 caggtcttga catccctctg accgctctag agatagagtt ttccttcggg acagaggtga
     1261 caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag tcccgcaacg
     1321 agcgcaaccc ctattgttag ttgccatcat ttagttgggc actctagcga gactgccggt
     1381 aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg acctgggcta
     1441 cacacgtgct acaatggctg gtacaacgag tcgcaagccg gtgacggcaa gctaatctct
     1501 taaagccagt ctcagttcgg attgtaggct gcaactcgcc tacatgaagt cggaatcgct
     1561 agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg ggccttgtac acaccgcccg
     1621 tcacaccacg agagtttgta acacccgaag tcggtgaggt aaccgtaagg agccagccgc
     1681 ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg tagccgtatc ggaaggtgcg
     1741 gctggatcac ctcctttcta aggataagga actgcgcatt ggtcttgttt agtcttgaga
     1801 ggtcttgtgg ggccttagct cagctgggag agcgcctgct ttgcacgcag gaggtcagcg
     1861 gttcgatccc gctaggctcc attggtgaga gatcaccaag taatgcacat tgaaaattga
     1921 atatctatat caaatagtaa caagaaaata aaccgaaaac gctgtagtat taataagagt
     1981 ttatgactga aaggtcagaa aataaggtta agttaataag ggcgcacggt ggatgccttg
     2041 gcactaggag ccgacgaagg acgtgacaaa cgacgatatg ccttgggtag ctgtaagtaa
     2101 gcgatgatcc agggatttcc gaatggggga acccaacagg taatacctgt tacccacatc
     2161 tgttaaggat gtgaggagga agacgcagtg aactgaaaca tctaagtagc tgcaggaaga
     2221 gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg gcagaagggc aaaccgaaga
     2281 gtttactctt cggggttgta ggactgcaat gtggactcaa agattataga agaatgattt
     2341 gggaagatca gccaaagaga gtaatagcct cgtatttaaa atagtctttg tacctagcag
     2401 tatcctgagt acggcgggac acgtgaaatc ccgtcggaat ctgggaggac catctcccaa
     2461 ccctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2521 ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt tcgagcccgt
     2581 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttat gatgcgaggt
     2641 taagttgaag agacggagcc gtagggaaac cgagtctgaa tagggcgcct tagtatcatg
     2701 acgtagaccc gaaaccatgt gacctaccca tgagcaggtt gaaggtgcgg taagacgcac
     2761 tggaggaccg aaccagggca cgttgaaaag tgcttggatg acttgtgggt agcggagaaa
     2821 ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc tagcgtcgac
     2881 attagagatt cttggaggta gagcactgtt tgggtgaggg gtccatcccg gattaccaat
     2941 ctcagataaa ctccgaatgc caatgaatta tggtcggcag tcagactgcg agtgctaaga
     3001 tccgtagtcg aaagggaaac agcccagacc accagctaag gtcccaaaat aattgttaag
     3061 tggaaaagga tgtggggttg cacagacaac taggatgtta gcttagaagc agctattcat
     3121 tcaaagagtg cgtaatagct cactagtcga gtgaccctgc gccgaaaatg taccggggct
     3181 aaaacaattt accgaagctg tggatacctt tataggtatg gtaggagagc gttctatgtg
     3241 tgatgaaggt ataccgtgag gagtgctgga acgcatagaa gtgagaatgc cggtatgagt
     3301 agcgaaagac aggtgagaat cctgtccacc gtaagactaa ggtttccagg ggaaggctcg
     3361 tccgccctgg gttagtcggg acctaaggag agaccgaaag gtgtatccga tggacaacag
     3421 gttgatattc ctgtactaga gtatgtagtg atggagggac gcagtaggct aactaaagca
     3481 gacgattgga agagtctgtc taagcagtga ggtgtgaatt gagtcaaatg cttaattcta
     3541 taacattgag ctgtgatggg gagcgaagtt tagtagcgaa gttagtgacg tcacactgcc
     3601 aagaaaagct tctagcgttt aaacatactc tacccgtacc gcaaaccgac acaggtagtc
     3661 gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa ggaactcggc aaaatgaccc
     3721 cgtaacttcg ggagaagggg tgctgacttt aagtcagccg cagtgaatag gcccaagcaa
     3781 ctgtttatca aaaacacagc tctctgctaa atcgtaagat gatgtatagg gggtgacgcc
     3841 tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag cgaaggtatg aattgaagcc
     3901 ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct tgtcgggtaa
     3961 gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt ctcaacgaga gactcggtga
     4021 aattttagta cctgtgaaga tgcaggttac ccgcgacagg acggaaagac cccatggagc
     4081 tttactgcag tttgatattg agtgtctgta ccacatgtac aggataggta ggagtctaag
     4141 agatcgggac gccagtttcg aaggagacgc tgttgggata ctacccttgt gttatggcca
     4201 ctctaaccca gataggtgat ccctatcgga gacagtgtct gacgggcagt ttgactgggg
     4261 cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc cctcagaatg gttggaaatc
     4321 attcgcagag tgtaaaggta taagggagct tgactgcgag agctacaact cgagcaggga
     4381 cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag ggccatcgct caacggataa
     4441 aagctaccct ggggataaca ggcttatctc ccccaagagt tcacatcgac ggggaggttt
     4501 ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt cggtcccaag ggttgggctg
     4561 ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt cgtgagacag ttcggtccct
     4621 atccgtcgcg ggcgtaggaa atttgagagg atctgctcct agtacgagag gaccagagtg
     4681 gacttaccgc tggtgtacca gttgtcttgc caaaggcatc gctgggtagc tatgtaggga
     4741 agggataaac gctgaaagca tctaagtgtg aaacccacct caagatgaga tttcccatga
     4801 ttatatatca gtaagagccc tgagagatga tcaggtagat aggttagaag tggaagtgtg
     4861 gcgacacatg tagcggacta atactaatag ctcgaggact tatccaaagt aactgagaat
     4921 atgaaagcga acggttttct taaattgaat agatattcaa ttttgagtag gtattactca
     4981 gagttaagtg acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag
     5041 ccctagaacg ccggaagtag ttgggggttg ccccctgtga gatagggaag tcgcttagct
     5101 ctagggagtt tagct
//
LOCUS       DAVMCN010000083         5060 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVMCN010000083 DAVMCN010000000
VERSION     DAVMCN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.084"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..708
                     /locus_tag="VYP85_001918"
     CDS             <1..708
                     /locus_tag="VYP85_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV1882374.1"
                     /translation="LKSKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVR
                     EVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNELDEVLSQVIVEMIDFYNIITVK
                     RGLSQNKSHGDILQLLSDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKM
                     QDATISSSELEFLCDLLLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNLRMIISALQN
                     TIPFESIKERIRPHYGS"
     gene            698..1018
                     /locus_tag="VYP85_001919"
     CDS             698..1018
                     /locus_tag="VYP85_001919"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV1882375.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            1081..2856
                     /locus_tag="VYP85_001920"
     CDS             1081..2856
                     /locus_tag="VYP85_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV1882376.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            2857..4242
                     /locus_tag="VYP85_001921"
     CDS             2857..4242
                     /locus_tag="VYP85_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV1882377.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            4265..4876
                     /locus_tag="VYP85_001922"
     CDS             4265..4876
                     /locus_tag="VYP85_001922"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV1882378.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         1666 a          721 c         1051 g         1622 t
ORIGIN      
        1 ttaaaatcta aggcggcaat taagaaagat ttttctaaat tattaattcc aatagggatt
       61 tttgatatag aaagtttaaa acatttagtt tcttccttac attcagatac acttcctgat
      121 tttatggttc gtgaagtaga atcaatttgg aatgagtatg aaacttttaa taatattcgt
      181 gtacttgatg tcggagctga tctagcatat tttaaacatc tgaaactttt atctaatgag
      241 ttagatgagg tactgtctca ggttattgtc gaaatgattg acttttataa tattattact
      301 gtaaaacgtg gtttatctca aaataagagt catggggata ttttacaatt actttcagat
      361 gaaggaagta tttctgctaa agaatttata tacattgtag aaaatcaaga aatatttgtg
      421 tggttcaata aaataaatcc aagcttagat tcaatctttt caacttatga attgaagatg
      481 caggacgcaa caatttcatc ttctgagtta gaatttttat gtgatttact attgtataaa
      541 actttagatc aaggaaggta caatgtagag gggccgttag ttcttgctag atatttattg
      601 ggatgtgagt ttgaagtaaa gaatctcaga atgatcatat cagctcttca aaatacaatt
      661 ccctttgaat caataaaaga aaggatacgc ccacattatg gaagctaata agtataaaat
      721 tggcataatt ggtagccgtg atattatttt accatttagc atgattgggt ttgatatatt
      781 tcctgcctac caagaacaag aagctataaa tacactaaga aaattagctc aatctgatta
      841 tggtgtcatt tatatcactg aagacattgc ttcaatgata ttagatacaa ttcgccatta
      901 tgattcccaa gttgtgcctg ctattatttt attaccgact cataaacaag gtttaaattt
      961 aggattaaaa cgtatagagg ataatgtaga gaaagcagta ggacacaata ttttataata
     1021 atgtacaaaa ttgtctgtaa tattattcta taatttttgg acttagtaag gagaataact
     1081 ttgactcaag ggaagattat aaaagtatcg ggacctctag ttattgcatc aggtatgcag
     1141 gaggctaata ttcaagatat ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt
     1201 gaaatgagaa gagatcaggc atctatccaa gtctatgaag aaacatctgg tcttggtccg
     1261 ggagaacctg ttgttacaac tggagaacct ctctcggttg aattagggcc tggattgatt
     1321 tctcaaatgt ttgatggcat acaacgccca ttagatcgat ttaaattggc tactcataat
     1381 gattttctag ttcgtggggt agaagttcca agtttggata gagatattaa gtggcatttt
     1441 gattccacta tatcaattgg tcaaaaagtg agtacgggtg atattcttgg aactgtcaag
     1501 gaaaccgaag tagttaatca taaaattatg gttccttatg gaatatctgg cgaagtcgtt
     1561 tctattgcct ctggcgattt tacaattgat gaagttgtat atgaaataaa aaaattggac
     1621 ggtagtttct ataaaggaac acttatgcaa aaatggcctg tccgcaaggc gcgtcctgtt
     1681 tctaaacgtt taatcccaga agaaccatta atcacaggtc aacgagttat tgatacattc
     1741 tttccagtaa ccaaaggggg agcagcagct gttcctggac cgtttggagc aggaaagaca
     1801 gttgtacaac accaagtagc taaatttgcc aatgttgata ttgttattta tgtcggttgt
     1861 ggagaacgtg gaaatgaaat gacggatgta ctgaatgagt ttcctgagtt gattgaccct
     1921 aataccggac aatcaattat gcaacggaca gttctgattg ctaatacttc aaatatgcct
     1981 gttgctgctc gtgaggcttc aatttataca ggaattacca tggctgagta ttttcgtgat
     2041 atgggctact ctgtcgccat tatggctgat tcaacttcac gttgggcaga agcgctacgt
     2101 gaaatgtcag gacgtctaga agaaatgcct ggtgatgagg gttatcctgc ttatctggga
     2161 agtcgtatcg ctgaatatta tgaaagagca ggacgttctc aggttctagg gcttccagaa
     2221 cgtgaaggaa cgattactgc tattggagct gtatcgccac ctggtggaga tatttcagaa
     2281 ccagttactc aaaacacttt acggattgtg aaagtttttt gggggcttga tgctccgttg
     2341 gcacagcgac gtcattttcc tgcaattaac tggcttacat cttattcact atataaagac
     2401 agtgtgggca cttatataga tggtaaagag aagacagatt ggaatagtaa aataactcgt
     2461 gcgatgaact acttacaacg ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt
     2521 gattctctgt ctgataatga acgactaacg atggaaattg ctaaacaaat tcgagaagat
     2581 tatttgcaac agaacgcttt tgattcggta gatacattca cttcgtttgc aaaacaagaa
     2641 gcaatgctaa gtaatattct cacttttgct gatcaggcaa atcatgcttt agagttgggt
     2701 tcttacttta cagagattat ggaaggtacc gtggcagttc gagaccgtat ggcgagaagt
     2761 aaatatgttt cagaagatag attagatgaa atcaaaatta tatcaaatga gattacacat
     2821 caaattcatt tgatattaga aacaggaggt ctataaatga gtgttataaa agaatacaga
     2881 actgctagtg aagttgttgg gcctcttatg attgttgaac aagtaaataa tgtgtcttac
     2941 aatgagttag ttgaaattca acttcataat ggagaaattc gtcgtggaca agttttagag
     3001 atccacgaag ataaagcaat ggttcagctt tttgaaggat ctagtggaat aaatttagaa
     3061 aagtctaaaa ttcgttttgc tggtcatgca ttagaattgg ctgtatctga ggatatggtt
     3121 ggtcgtattt ttaatgggat gggaaaacca attgatggtg gaccagattt aattccagag
     3181 aaatatttag atattgatgg tcaagctatt aatcctgtat ctagagatta tccagatgaa
     3241 tttattcaga cagggatctc ctctattgat catttgaata ctcttgtacg tggtcaaaaa
     3301 ttaccagtat tttcaggttc gggcttacct cataatgaat tagctgctca gatagcaaga
     3361 caagcgactg ttttaaattc tgatgaaaat tttgcggttg tatttgcagc aatgggtatt
     3421 acttttgaag aagctgagtt ttttatggaa gaactcagaa aaacaggagc gatcgatcgt
     3481 tcggttttat ttatgaactt ggcaaatgat cctgcaattg agcgtattgc aactccccgc
     3541 attgctttaa ctgcggcaga gtatctagct tttgaaaaag atatgcacgt tctagttatc
     3601 atgacggata tgactaacta ttgtgaagcg ttacgtgaag tctcggcagc tcgccgtgaa
     3661 gttccaggga gacgaggcta tccgggatat ttatatacaa atttatcaac tctatacgaa
     3721 agggctggtc gcttagttgg taaaaaaggt tcggtgacac agattcctat tttaacaatg
     3781 ccagaagatg acataacaca tccaattcct gatttaactg gatacattac tgaagggcaa
     3841 attattttgt cgcatgagtt gtataatcaa ggttatcgtc caccaatcaa tgttttacct
     3901 tctctctctc gattaaaaga taagggatct ggagaaggta aaactcgtgg agatcatgct
     3961 ccaactatga atcaactgtt tgcagcctat gcccaaggga aaaaggttga agagttagca
     4021 gtagtattag gagaatcggc tttatctgat gtagataaat tgtatgtgag gtttacaaag
     4081 cgttttgaag aagagtacat aaaccaagga ttttataaaa atcgaaatat agaagatacg
     4141 ttgaatcttg ggtgggaatt actatcaatt cttcctagaa cagagttaaa acgtatcaaa
     4201 gatgatttgc ttgataaata cttacctttg gtagaagttt aatccggaaa tggagtgatt
     4261 atctatggta cgtttgaatg taaaaccaac tcgtatggaa ttgaataact taaaggaacg
     4321 tttgacaaca gctgaacgtg gacataagtt attaaaggat aaaagagatg aattgatgag
     4381 gcgatttatt tctttgattc gtgagaataa tcaacttcgg aaagaagtgg aaagttatct
     4441 aattgataat ctaaaatcct ttgcagttgc taaatcatta aagaattctc aaatggtgga
     4501 ggaattattt tcaattccat cgaaagaaat tgaattattt gttgagaaag aaaatatcat
     4561 gagtgtaaca gttcctagaa tgcatatgaa tattacttct caaaatgaga acagtgaata
     4621 cagctattta tcttctaata gtgaaatgga tgatgtattt gctacaatga atagtttaat
     4681 ttataaatta ctaagactgg cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat
     4741 agaaaaaaca cgtagacgtg taaatggttt agaatactcg attattccaa acttgtcgga
     4801 aactattcat tatatagaat tgaaactaga ggaggcagaa agagccaatt tagttcgtat
     4861 tatgaaagtg aagtagatcc tttatttaga ttattaatta gatgaacaaa tatcagcttg
     4921 gataaggctt taagcctttc taagcttttt ttattgacag tatcaggata tctttttcaa
     4981 aattttggtt tgttagataa tgaaaatgtt tctactaatc tagatttagg attagtaaat
     5041 cgtaaatgta attatataga
//
LOCUS       DAVMCN010000084         4914 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVMCN010000084 DAVMCN010000000
VERSION     DAVMCN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.085"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..787
                     /locus_tag="VYP85_001923"
     CDS             <1..787
                     /locus_tag="VYP85_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HEV1882379.1"
                     /translation="KDFSQFLKSYNFKEVSHKEIEQRKIFSMWIQGYESAPKLVQKTI
                     DSQRKYAEKYGYKFVFLDENNIREYVTLPSEIVEKYENGTIDFIKYSDVVRGTLLSKY
                     GGVWLDSTIYVDSSRELNYLKKDFYTIRAKTHERVPKYIANGRWSAFCLSGEKQNIVF
                     DFLEKFHVAYFMKYDIVLDYFLIDYIIELGYRTNDLIRNYIDKVEENNQELFFLADNF
                     SNQYDEKEWAGVLSTTALFKCSYKCPINEATGTYFDRLMKGEL"
     gene            807..1778
                     /locus_tag="VYP85_001924"
     CDS             807..1778
                     /locus_tag="VYP85_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1882380.1"
                     /translation="MISVIVPVYNVADYLRFALDSLLEQTYKDFEVILVNDGSTDNSG
                     EICDEYGKLYDNIHVFHKKNGGLSDARNFGLEKSRGEFITFLDSDDYFEPYALELLIT
                     IQKKYDVDIVSTKGGITYSHDIYSKKLMAEDYLTVKILTNKEFLAAVYYNDEMTVSAW
                     GKLYKRDLFKTIFPKGKIYEDLYVVAERLLNIKTVAHTDLPIYHYYQRQGSIVNSTFS
                     DRQYDFFDAIDHNEAIIKKFYCGDKELLAALNAKRVIGSFILSNSAFYNSKNDITKII
                     RIIKPYYWEVIKNKKIPMKRKVQCVLFLLSPNYYYKIKDKMLQRGRI"
     gene            1779..3002
                     /locus_tag="VYP85_001925"
     CDS             1779..3002
                     /locus_tag="VYP85_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1882381.1"
                     /translation="MHVRLDGLLDYIFLFSVIITCNTMYSTSQGFDGLGKWATLLLVV
                     SVFLKLLISRISMKAINVIVSRSLIFILIILLIVILNGFKISETSFVYYFVLFPIFMM
                     ILQMYYDVNEIANLIRKFVRIIFLLAIGSLLFWLIGSVFHIISPTVYVLNYWNGGGIV
                     EGYYNLHFEAQKIEILGAILIRNTGIFAEAPMWSLVLSLALIFQTLHIKKWNFTTWTL
                     IITIMTTTSTTGVYIIGLIFLYVLFSKTSGVKRYVSSLFILAIICCFSILWDNKSGTG
                     SATIRFDDYKAGFLAWQKSPIWGLGISDGLRTIEQHMDRTVRYNLGYSNSFFVVLAQG
                     GIMLASYYFYPVIKIILNKFSSNDLKFSALLIIFLMITTIFIETYMFLFVISLYYSLD
                     FGDDRDCHEKQYITN"
     gene            3033..4448
                     /locus_tag="VYP85_001926"
     CDS             3033..4448
                     /locus_tag="VYP85_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003009066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEV1882382.1"
                     /translation="MKILKNYAYNLSYQLLVIILPIITTPYVTRVFSSDDLGTYGYFS
                     SIVTYFTLLATLGVANYGTKEISAHRKEIGKNFWGIYSLQFGATWLSILLYLALCFLF
                     TSMQNPVAYILGLSLVSKGLDISWLFQGLEDFRKITVRNITVKLVGAISIFLFVKSAN
                     DLYLYVFLLTIFELLGQLSMWLPARQFIGKSYFDWKYAKKHLKPVILLFLPQIAISLY
                     VTLDRTMLGVLASTKDVGIYDQALKLVNILLTLVTSLGSVMLPRVSSLLSSGDYKAVN
                     KMHEMSFLIYNLVIFPIIAGMLIVNDDFVRFFLGQNFQDARYAIAIMTFRMFFIGWTN
                     IMGIQILIPHNKNKEFMVSTTVPAILSVGLNLLLLPQFGYIGAAIVSVLTEAFVWGIQ
                     LFYTRFYLKEVPIIGSMTKTALASAVMYGLLLGSKTSIHFSPTINVLIFSVLGGIIYL
                     FAILSLKVVDVKELKQIIRKN"
     gene            4450..>4914
                     /locus_tag="VYP85_001927"
     CDS             4450..>4914
                     /locus_tag="VYP85_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEV1882383.1"
                     /translation="MSKFRNINLDLLKVLACVGVVLLHTTMGGFKETGAWNFLTYLYY
                     LGTYSIPLFFMVNGYLLLGKREITYSYILQKIKWLLITVSSWTFIVWLFKRDFTENLI
                     KKIIGSLIQKGYFFQFWFFGALILIYLCLPILRQFLNSKRSYLYSLSLLMTIG"
BASE COUNT         1543 a          634 c          957 g         1780 t
ORIGIN      
        1 aaaagatttt agccaatttt taaaatccta taactttaaa gaggtatcgc acaaggagat
       61 agaacaaaga aaaatcttct ctatgtggat acaaggatac gaaagtgctc ctaagttggt
      121 tcagaagacg attgatagcc aaaggaaata tgcagaaaaa tacggatata aatttgtttt
      181 tttggatgaa aacaatatcc gtgaatatgt gacacttcca tcagagatag tagaaaaata
      241 tgagaatgga actatagatt ttataaaata ttcggatgtt gtaaggggaa cattgctttc
      301 aaaatatgga ggagtgtggt tagattcgac tatttatgtt gattcttcac gagaactgaa
      361 ttatttaaaa aaagattttt atactattcg agcaaagaca catgagagag tgcccaaata
      421 tatcgcaaat ggtaggtggt ctgcattttg tttgtcaggg gaaaagcaaa acatagtatt
      481 tgatttttta gagaaatttc atgtagcata ttttatgaaa tacgatatag tgctagatta
      541 ttttttaatt gactatatta tagaattagg ttataggaca aatgacttga ttagaaacta
      601 tattgataaa gtcgaagaaa ataatcagga gttgttcttt ttggcagaca atttttctaa
      661 ccagtatgat gaaaaagagt gggcaggagt tttatcaaca actgcattgt ttaagtgtag
      721 ttataagtgt ccgataaatg aagcgacagg aacctatttt gatagattga tgaagggtga
      781 actgtagcat aaagagaggg aatggtatga tttcagttat tgttccagta tacaatgtcg
      841 cggattatct gcgctttgcg ttggatagtc ttttggaaca gacgtataaa gattttgagg
      901 ttattctagt aaatgatgga tccactgata attctgggga aatatgtgat gaatatggga
      961 aactgtatga taatattcat gttttccata agaagaatgg cggactttcg gatgctagaa
     1021 attttggttt ggagaagagt cgaggagagt ttataacttt tcttgattca gatgattatt
     1081 ttgaaccgta tgcattagaa ttgttaatta ctattcaaaa aaaatatgat gtagatatcg
     1141 tatcaactaa agggggaata acctattctc atgatattta tagcaaaaaa ctgatggctg
     1201 aggactacct aactgtaaaa atattgacaa ataaagaatt tttggcagct gtatattata
     1261 acgatgaaat gacggtatct gcttggggaa aattgtataa aagagattta tttaaaacga
     1321 tttttccaaa aggaaagatc tacgaggatt tgtatgttgt tgcagagcgt ttgttgaata
     1381 ttaaaacagt tgctcatacc gatttgccta tatatcatta ttatcagaga cagggaagta
     1441 ttgttaattc aacattttcg gatagacagt atgatttttt tgatgcgatt gatcataatg
     1501 aagccataat aaaaaaattc tattgtggag ataaggaatt gttagcagcc ttaaatgcta
     1561 aaagagtaat tggctccttt attttgagta atagcgcatt ttataatagt aaaaacgata
     1621 ttactaaaat aataagaata attaaaccgt attattggga agtaataaaa aataaaaaaa
     1681 ttccaatgaa aaggaaagtt caatgtgttt tgtttctgct ttccccaaat tactactata
     1741 aaataaaaga taagatgtta cagagaggca ggatatagat gcatgttaga ttagatggtt
     1801 tgctggacta tatatttcta tttagtgtga ttattacttg taatactatg tattcaacta
     1861 gtcaaggatt tgatggacta gggaaatggg cgactctgtt acttgtggta tcagtttttc
     1921 tgaaattgct tatctctaga atatctatga aggcaatcaa tgtgattgtg tcgcgttctt
     1981 taatatttat attaattatt ctactcatag taatattaaa tggttttaag atttctgaga
     2041 caagtttcgt ctattatttt gtattatttc cgatttttat gatgattttg cagatgtact
     2101 atgatgttaa tgaaatcgca aatctgatac ggaaatttgt tcgtataata tttcttttag
     2161 caattggctc tctcctattt tggcttattg gtagtgtatt tcatattata tccccaacgg
     2221 tttatgtgtt gaattattgg aatggtgggg gaatagtaga agggtactat aatcttcatt
     2281 ttgaagcaca aaaaatagag attttggggg cgatactgat aagaaatacg gggatttttg
     2341 ctgaagcacc tatgtggagt ttggtattga gccttgcatt gatatttcaa acgcttcata
     2401 taaaaaaatg gaatttcaca acttggactc ttattattac aattatgaca actacgtcaa
     2461 caacaggggt ttatataata ggtttgattt tcctatatgt tttattttca aaaacaagtg
     2521 gtgtgaagag atatgtttct agtttattta ttttagcgat tatatgttgt ttttcaatat
     2581 tatgggataa taaatctgga actggttcag caactatacg ctttgatgat tataaggctg
     2641 gttttttggc atggcagaaa agtcctattt ggggattagg tatttcagac ggtcttagaa
     2701 ccattgaaca acatatggat agaactgtta gatataatct tgggtatagc aatagctttt
     2761 ttgttgtttt agctcaagga gggataatgt tggcttcgta ttacttttat ccagtaatta
     2821 aaattatttt gaataaattt agttcgaatg atttgaagtt ttctgcgcta ttaataattt
     2881 tccttatgat aactactata tttatagaga cctatatgtt tttatttgtc atttctttat
     2941 actattctct tgattttggg gacgatagag attgtcatga gaaacagtac attactaatt
     3001 aataataaag gtgtgaacag aaataagaag aaatgaaaat actaaaaaac tatgcctaca
     3061 atctttctta tcaattgttg gtgatcatac tccctatcat tacgactccc tatgtaacga
     3121 gggtttttag ttctgacgat ttaggaacgt atggctactt tagctccatt gttacctatt
     3181 ttaccttgct tgcaactctt ggtgttgcca actacggtac caaagagatt tcagcacatc
     3241 gtaaggaaat tgggaagaat ttctggggaa tttattctct ccagtttggt gcaacttggc
     3301 tatccatttt gctttatctt gccctttgtt tcttatttac ttcaatgcaa aatccggtag
     3361 cttatatatt gggattaagt ttagtgtcaa aaggtttgga tatttcttgg ttatttcaag
     3421 gtttggagga ttttagaaag attacagttc ggaacatcac tgttaagtta gttggtgcaa
     3481 tctctatttt cctatttgta aaatcagcta atgacttata cttatatgta tttcttctta
     3541 ccattttcga attgttaggg caattaagca tgtggttacc cgcaagacaa tttattggta
     3601 aatcatattt tgattggaaa tacgctaaga agcatttgaa accagttatc ttgttattct
     3661 tgccacagat tgccatctcg ctttatgtga ctttggaccg tacgatgctg ggggtgttgg
     3721 cttcgacaaa ggatgttgga atttatgatc aagctttgaa gcttgttaat attttactga
     3781 ctttggttac ctcactgggg agtgttatgt tgccacgagt atctagcctt ttatcgtctg
     3841 gggattacaa agccgttaat aagatgcacg agatgtcttt tttaatctat aacttggtga
     3901 ttttcccaat catagcagga atgttgattg tcaacgatga ttttgttcgt ttcttccttg
     3961 ggcaaaattt tcaagatgct cgctatgcga ttgctattat gaccttccgt atgttcttta
     4021 ttggttggac caatataatg ggaattcaaa tcttgattcc gcacaataaa aataaggaat
     4081 ttatggtttc aacgacagtt cccgctattc tgagtgtggg attgaatttg ttgcttcttc
     4141 cccaatttgg ttatataggt gctgcgattg tttcagtttt gactgaggcg tttgtatggg
     4201 ggattcagtt attctataca cgtttttatt taaaagaagt tcctattatc ggttcaatga
     4261 caaaaactgc acttgcatct gctgttatgt atggtctctt gctaggttca aaaacatcta
     4321 tacatttttc gccaaccata aatgttttaa tattttcggt gctaggcgga attatctatc
     4381 tttttgcaat tctatctctg aaagtggtag atgtgaaaga attaaaacaa ataatcagga
     4441 aaaattagaa tgagcaaatt tcgaaatatt aacttagatt tactaaaagt gcttgcatgt
     4501 gttggagtcg ttctacttca tacaactatg ggtgggttta aagagacagg tgcatggaat
     4561 tttttgacat atttatatta cttaggaacc tattctatcc ctctattttt tatggtcaat
     4621 ggttatttat tgttggggaa gagagaaatt acctattcct acatattgca aaaaataaaa
     4681 tggctcctaa taacagtgtc gtcatggact tttatcgttt ggctgtttaa aagagacttt
     4741 acagagaact taattaaaaa aattataggt tctttgatac aaaaggggta tttcttccag
     4801 ttttggtttt tcggtgcact catacttatc tatttatgtt tgccaatttt gagacaattt
     4861 ctaaattcaa aaagaagcta tttatacagt ttatctttat tgatgactat tggt
//
LOCUS       DAVMCN010000085         4890 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVMCN010000085 DAVMCN010000000
VERSION     DAVMCN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.086"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            22..240
                     /gene="nrdH"
                     /locus_tag="VYP85_001928"
     CDS             22..240
                     /gene="nrdH"
                     /locus_tag="VYP85_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1882384.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            321..2480
                     /gene="nrdE"
                     /locus_tag="VYP85_001929"
     CDS             321..2480
                     /gene="nrdE"
                     /locus_tag="VYP85_001929"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1882385.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            2668..3630
                     /gene="nrdF"
                     /locus_tag="VYP85_001930"
     CDS             2668..3630
                     /gene="nrdF"
                     /locus_tag="VYP85_001930"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1882386.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            3812..4573
                     /locus_tag="VYP85_001931"
     CDS             3812..4573
                     /locus_tag="VYP85_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1882387.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(4772..>4890)
                     /locus_tag="VYP85_001932"
     CDS             complement(4772..>4890)
                     /locus_tag="VYP85_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1882388.1"
                     /translation="CHSDDELEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
BASE COUNT         1579 a          975 c          895 g         1441 t
ORIGIN      
        1 attttgaaga ggagttacac aatggtaacc gtttattcta aaaacaattg tgtccaatgt
       61 aaaatgacca agcgtttctt ggacagtaat aatgtctctt atcgtgaaat caatcttgat
      121 gagcaacctg agtacgtcga tcaagttaaa gagctcggtt ttagcgcagc tcctgttatc
      181 caaacaccaa ctgaagtctt ttcaggtttc caaccaggaa aactgaaaca attagcataa
      241 tcttagtaca tcatccagaa gaaactgctt ttagggctaa cttagaagcc tttcttttgt
      301 aattagataa gggaaatttt atgggattaa aacatcttga agacgtgact tacttccgtc
      361 ttaataacga aattaaccgt cctgttaatg gacaaatcat gcttcataaa gataaggaag
      421 ccttggatgc tttctttaaa gaaaatgtag ttccaaacac tatggttttt gattcaatca
      481 aagacaaaat caattacctc attgaacaca actacatcga aacagccttt atcaagaaat
      541 accgtccaga gttcttggaa gaattggctc aatttatcaa agaccaaaac ttccaattca
      601 agtcattcat ggcagcttat aaattttaca atcaatatgc cttaaagact aatgacggtg
      661 aatactatct tgaaaatatg gaagaccgtg tcttcttcaa cgccctttat ttcgctgatg
      721 ggaatgaagc tgttgcaatc gatattgcca atgaaatcat ccaccaacgc taccaacctg
      781 ctactccttc cttcttgaat gctggacgtg ctcgtcgtgg ggagttggta tcttgtttcc
      841 taatccaagt gacggatgat atgaactcta tcggacgttc tatcaactca gctcttcaac
      901 tttcacgtat tggtggtggt gtgggaatta ccctcagcaa ccttcgtgaa gctggtgcac
      961 ctatcaaagg ctatgaagga gctgcttcag gtgtcgttcc tgttatgaag ctttttgaag
     1021 acagcttctc ttactccaac caattggggc aacgtcaagg tgctggtgtt gtctacctca
     1081 acgtctttca cccagatatc atcgctttcc tttcaactaa gaaagaaaac gctgatgaaa
     1141 aagtacgtgt caagactcta tcacttggtg ttgtagtacc tgataaattc tacgaattgg
     1201 ctcgtaaaaa tgaagaaatg tacctcttca gcccttactc tgtagaaaaa gaatacggtg
     1261 tgccattcaa ttacatcgac attactgaaa aatacgatga attggtcgca aatccaaata
     1321 ttcgcaagac aaaaatcaag gcgcgggatt tggaaactga aatctctaaa ttgcaacaag
     1381 agtctggcta tccttatgta gtcaacatcg atacggctaa ccgtgcaaat cctgttgatg
     1441 gaaagattat catgagtaac ttgtgttctg agattcttca agttcaagaa ccaagcttga
     1501 tcaacgatgc tcaagaattc cttcaaatgg gaacagatgt ttcatgtaat ctgggttcaa
     1561 ccaacgtggt taacatgatg acttcacctg attttggtcg ttctatccgt gctatggttc
     1621 gtgcccttac tttcgttaca gatagttcac atatcgtagc tgtaccaacg attgaccatg
     1681 gaaatagcca agcccacacc tttggtctcg gtgccatggg actgcacagc taccttgccc
     1741 aacaactcat tgaatatggt tcacctgagt ctgttgaatt tacaagcatc tactttatgc
     1801 ttatgaacta ctggaccttg gtagagtcaa acaatattgc gcgtgaacgt ggtattacct
     1861 tccacaactt tgaaaaatca gactatgcta acggaagtta ctttgacaag tatgtaactg
     1921 gtgaatttgt tccaacatca gaccgtgtta aagaactctt caaaaatgtt tttatccctg
     1981 gtgttgctga ttgggctgaa cttcgcgaca aggttcaaga agatggtctt taccaccaaa
     2041 atcgccttgc tgtagcgcca aatggttcta tcagctatat caacgacgtt tctgcttcta
     2101 tccacccgat tacgcaacgt atcgaagaac gccaagagaa gaaaattggt aaaatctact
     2161 accctgctgc tggcttgtct acagaaacca ttccttacta cacttctgcc tacgatatgg
     2221 atatgcgtaa agtcatcgat gtttacgctg ctgcgactga acacgtggat caaggacttt
     2281 cactcaccct cttcatgcgc agtgacattc caaaaggcct ttacgaatgg aagagggaaa
     2341 ataaacaaac gacacgtgac ttgtctatcc ttcgtaacta tgcctttaac aagggaatca
     2401 agtctatcta ctacgtccgt acctttacag atgacggtgg agaagtcggc gccaaccaat
     2461 gtgaaagctg tgtgatttag tttctagcat agaaacatta tttttcccta agcagcactg
     2521 ataaaatcaa atctactatg tcataacata atttatgtaa cattttaaaa gtcggacttc
     2581 cgactttttg tgcgatactc ctatagaatt atggtaaagt agaaataatt gtgagttcgc
     2641 aatactaaac acagaaagag attttaaatg gaaacttact acaaagccat taactggaat
     2701 gccatcgaag atgtcatcga caaatcaact tgggaaaaac tgacggagca attttggctc
     2761 gatacacgta ttcccttatc aaacgacttg gatgactgga gaaagctatc taacaaagag
     2821 aaagacttgg tcggaaaagt ttttggtggt ttaacccttc ttgacactat gcaatctgaa
     2881 actggggttc aagcccttcg cgcagacatc cgtacaccac atgaggaagc tgttttcaat
     2941 aacatccaat ttatggaatc tgtccacgct aaatcttact catcaatctt ttctaccttg
     3001 aatactaagg ctgagattga agaaattttc gaatggacca ataccaatcc ttacctacaa
     3061 aagaaggctg agattgtcaa cgaaatctac ctaaacggca gcccacttga aaagaaagtt
     3121 gccagcgtct tcctcgaaac cttcctcttc tactctggtt tcttcactcc cctctactat
     3181 ctcggtaaca acaaactagc caacgttgca gaaatcatta aattgattat tcgtgacgag
     3241 tctgttcacg gaacctacat tggttacaaa ttccaacttg gtttcaatga attgcctgaa
     3301 gaagagcaag aaaaactcaa agaatggatg tacgacctac tctatactct ttatgaaaat
     3361 gaagaaggct acacagagag tctttatgac ggtgttggtt ggactgaaga ggttaaaacc
     3421 ttccttcgct acaatgccaa taaagctctc atgaacatgg gacaagatcc acttttccca
     3481 gattcagctg aagatgtcaa cccaatcgtt atgaacggta tttcaacagg aacttccaac
     3541 catgacttct tctctcaagt cggaaatggt taccttcttg gcgaagttga agccatgcaa
     3601 gacgatgact ataactacgg tttagactaa ttctccatca ctctcaatca tcaaaaagta
     3661 aactagaaac atcaaagtta taacccaaca aaaatatcga aagttttgaa aacaaacttc
     3721 gatatttttg tttttgtttc attttgttgt ttttgtattt gaatgatgag tttgtttatg
     3781 gtaagatagt agtaggaaac gaggtgataa tatgctcaaa caagaaaaat tagccaaaat
     3841 tttagagata gtaaatagta aaggaaccat aacggttaaa cagattatgg acgaaatagc
     3901 cgtttcagat atgactgcaa ggcgctattt acaggaatta gctgataaag atttgctgat
     3961 tcgtgtgcat ggtggagctg aaaaacttcg aaccaactcc cttttgacta atgagcgatc
     4021 aaatattgaa aaacaagccc tccaaacggc agaaaaacaa gaaatagccc attttgcagg
     4081 cagtctagta gaagaaagag aaactatttt cattggacca ggaacaacat tagagttttt
     4141 tgcgcgtgag ttgcctattg acaatatccg cgtcgtaacc aacagtctac ctgtttttct
     4201 gattttaagc gaacgaaaat taacagattt gattttaata ggtggaaatt atcgcgatat
     4261 tacaggtgct tttgttggca cattgaccct acaaaatctc tctaatctcc aattttctaa
     4321 agctttcgtt agctgtaatg gtattcaaaa cggagctcta gctactttta gcgaggaaga
     4381 gggagaggct caacgcatcg ctttaaataa ttctaataaa aaatatttac tcgcagatca
     4441 tagtaagttc aataagtttg atttttatac tttttataat atatcaaatc ttgatactat
     4501 tgtttcagat tctaaactaa gtgattcaat cctttttaag ctatctaaac acattaaagt
     4561 catcaagcct taataaactg aaagagcctg ggtaacaact caatttcaga agaaaaaaag
     4621 taaatcttcc cacaataaaa agcatagtat caggtgtttc aacacctgat actatgcttt
     4681 tttctatgat tttcattgag tataagcaac gtgattagat aagagtttta cagagtacta
     4741 aatataagat ttaacttttt tgagaaattg gttacgattg ttgaaacggc ataaaatctg
     4801 aatcaaagga gatagtatcc cattcttcag gattgataaa atttaaaaat agatttttaa
     4861 attcttccag ctcatcatct gaatgacaaa
//
LOCUS       DAVMCN010000086         4735 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVMCN010000086 DAVMCN010000000
VERSION     DAVMCN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.087"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(360..1088)
                     /locus_tag="VYP85_001933"
     CDS             complement(360..1088)
                     /locus_tag="VYP85_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1882389.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1246..2655
                     /locus_tag="VYP85_001934"
     CDS             1246..2655
                     /locus_tag="VYP85_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1882390.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDFEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2673..3968
                     /locus_tag="VYP85_001935"
     CDS             2673..3968
                     /locus_tag="VYP85_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1882391.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3973..4281
                     /locus_tag="VYP85_001936"
     CDS             3973..4281
                     /locus_tag="VYP85_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1882392.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4278..4586
                     /locus_tag="VYP85_001937"
     CDS             4278..4586
                     /locus_tag="VYP85_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1882393.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1595 a          808 c          876 g         1456 t
ORIGIN      
        1 tgggagattg aaattcattt ctagcaattt gttagaagtc acagtctact attctaacct
       61 cagtatacta tatgtgttac aagaaaagac tcaaaaactt ctcgtcagtg taagaatatt
      121 tgaaacacta tttaaaacta aataactata agaagtagat caggtgaaca atttcagtac
      181 ctactctata agctatacga agatattttt caacatgatg gataaaacga tcactctttt
      241 aaagccatct tatttagaaa agagaaacca tttaagcata gatgggacct tcttgccctg
      301 ttttaaattt ttcttaaact agagtctgta aaagattggc ttcattttca cattttctcc
      361 taggaggaat gtcgtaatgc aaaagaatta aattcaaata aatcatagcg atgacgacta
      421 atcgagtact caaacggagt tccgttatcc aaataagcca cttgttctac ttcaaatacc
      481 ggttccgttg gaaggagctg caagtaatgt tgctcatttt ctgaactaga agaagctcgt
      541 aagatttttg tagcactggc aatatgcaat cctaactttc cttcaatgta attgtaaatc
      601 gatttttgta aaatatcttc agtaatacct ggaataacat cggtactcat ataagtttgt
      661 tccagaacat aaggtttacc gtcaataata cgcaggcggt aaatattata aactggactc
      721 tgcaaagcga cctgtagttt ttctgctaaa aattcatttg caaattctaa tttgaagtga
      781 ataatcctcg agtcaattgt agaatgagca tcttcagata tttttgtcag tccccggata
      841 tctctttctg gaacgattaa ttttcttttt gagctgccac gagagagaac aaaggttccc
      901 tgcccacgtt ttctaaaaat taagccctca gaaactaaca agtctaaagc ttttttgatc
      961 gtcattcgac tacaggcaaa ctgtttagct aatgtcattt catcaggtaa ttgttcgttc
     1021 atggtatatt tattacaaag aatcttttca cgaatctcat tgtaaataaa taaatatttt
     1081 gtactcattt aatctggttc tctctataat attctaatag tagtataaca aagttcaaga
     1141 aatgaggcaa acacaagata tgtatcaaca atttttaaaa atgtctagac aaattttgaa
     1201 attatgctat actttatgta tagaataata gaaaggaggt tgagcatgaa aaaaaagtta
     1261 gtatttccta atctgttttg gtggggagca gcttctagcg gacctcagac agaaggtcaa
     1321 tatggaaaag tacatgaaaa tgtgatggac tactggttca aaacgcatcc agaagatttt
     1381 ttcgataatg tcggacctct tgtagccagt aacttttttc atacttacac cgaagatttc
     1441 cacttgatga aggaaattgg agttaattct ttccgcactt ccatccaatg gagtcgactc
     1501 atcaagaatt tagagacagg tgagcctgat ccaaaaggta ttgctttcta caatgccatc
     1561 attgaagaag ctaaaaagaa ccagatggat cttgtgatga atttacatca ttttgattta
     1621 ccagtggaac ttcttcaaaa atacggtggt tgggaaagca aacatgtagt ggagttattc
     1681 gtgaagtttg ccaagactgc tttcacatgc tttggagata aggttcatta ctggacaact
     1741 ttcaatgagc caatggtcat tccagaagca ggatacttat atgctttcca ttatccaaat
     1801 ctaaaaggaa agggaaaaga ggccgtacaa gtcatctata atctaaacct tgctagtgca
     1861 aaagtgattc aactatatcg ctcattagaa cttgatggaa agattgggat tattttaaac
     1921 ttgacacctg cttatccaag aagtaattct ccagaagact tcgaagcaag tcgatttaca
     1981 gatgacttct ttaacaaagt cttcttgaat ccagctgtta aaggaacttt cccagaaaga
     2041 ttggtaaaac agctagagag agatggcgtg ttatggagtc ataccgaaaa agagcttcaa
     2101 ctgatgaaat caaatacggt tgattttctt ggagtaaact actaccatcc aaaacgtgtt
     2161 caagcacaag caaatcctga ggaatatcag acgccctgga tgccagacca atacttcaaa
     2221 gagtatgaat ggctggagcg tcgcatgaat ccatatcgtg gttgggaaat ttttccgaaa
     2281 gccatttatg atattgctat gattgtgaag gaagaatatg gtaatatccc atggtttatc
     2341 agtgaaaacg gaatgggtgt tgaaaacgaa gcacggttta tcgatgaaaa tggagttatc
     2401 gatgacgtgt atcgtattga attttatgaa gaacatttaa gatggctaca taaagccatt
     2461 gaagagggaa gtcactgttt tggataccac gcttggaccg catttgattg ctggtcttgg
     2521 aataatgcat ataagaatcg ttacggattt atctccgttg atttagaaac gcaaaagaga
     2581 accatcaaga gctcaggaag atggtatcgc aaagtaagtg acaataacgg ttttgaagta
     2641 gaaattgagg agtaaagaga ggagatattc atatgaaaaa ctcaaaattt atagaccaat
     2701 ttgccacctt tgctggtaaa ctagggaacc aaattcattt aaaaacccta agagatgcat
     2761 tcgtaacagt aatgccatta tatattttgg caggtttaat cgttcttttg aacaacacgg
     2821 tatttaagtg gattttccaa ggggatacat taacaagatt ccaatattgg ggaataacaa
     2881 ttgcaaacgg tactttaagt atttcaggta tgattattgc tgtaatggtt ggttatttct
     2941 tagctaaaaa cagagatttc gaaaacccgt tagcagcatc aatgctatca ttagtttctt
     3001 taattgtgat gatgccaaat acagtttctg tagttcctga cggagcaaaa gatgctgtaa
     3061 acatttcagg tgttctttca ttcaacaaca caggtacagg cgcaatgttc gccggggtta
     3121 tcgtagcgat tattgcaaca gaattattca ttgaattatc aaatgttaaa gctttacaaa
     3181 tgaaccttgg tgaaaatatt ccaccagctg ttagtagatc atttagcgta ttacttccag
     3241 tcatgaccgt catctcctta tttggggttg tttcagcatt attgttcaat ataactggaa
     3301 tgaacttaat ctcaatcatt acaatcttta ttcaagaacc aattcgtcat attggtacaa
     3361 gcttaatcgg ggtcattatt atttactctt taggaaatat gttatggcta tttggtattc
     3421 accaagcagt tatttacagt gccatcctag aaccattact attaattaac attactgaaa
     3481 acatcactgc agcaaataat ggacaagcca ttccacacat catcaaccta tcacaaatac
     3541 aaacattcgc tttaatgggt ggtagtggat ctacattatg tttattaata gcaacattct
     3601 tagtgagtcg caatgctgtc tctaaaaacg tggctaaatt atcttttgga cctggtatct
     3661 tcaatatcaa tgaaccagta ttattcggtt acccaatcgt ttataacatt tcattagcta
     3721 ttccatttat cacagttcca gtccttggta ttttaatcag ctacttagca acagttacag
     3781 gattcatgag tcctgcattt atacaagttc cttggactac accagtattc ttaaatgcat
     3841 ggttagcaac agcaggggac gtgagagcag ttctagttca attcatcatc tttgcacttg
     3901 gagttcttct atacattcca tttatcaaag ttaatgacaa agttgttgaa caagaaatgg
     3961 aaggttaaga ttatgaaaca aattttatta gtatgtaatg cgggaatgtc gacaagtatg
     4021 cttgttaaaa aaatgcaaca aagtgcgact gaacgtggga ttgaaatctc tatccaagca
     4081 aaatcaatga cagaagctaa aaagaatatc catgaagcag atgtcattct aattgggcca
     4141 caaattcgtt atgagttact tgctgtgaaa gaaattgcag gaaatatccc tgtagatacc
     4201 attgatatgc gggattacgg aatgatgaat ggagcaaaag ttctggaaca agcacttgca
     4261 tggataggag aaataagatg acagaagaaa tggaatatat ctgttttcag ctcattgcca
     4321 atagtggagc agccaaatca tcctttattg aagccatcca actagctaag gcaggaaatt
     4381 taaaagaagc gaaaattaaa gttgaagaag cggaagactc cttagtagaa gcgcacaaga
     4441 ttcactctaa tctcatacaa aaagaagcta ctggagaaaa aataggattc tccttgctat
     4501 ttatgcatgc agaagaccaa atggcttcaa cagagattat tcagttgcta tctaaagaat
     4561 tcatcgatct ctatcaaaat aaataggaac actgtcattc ccatctgtct ttattaatga
     4621 cgactacatt gtaggaacct ccaaaagttg gacaaaatga ttgaaaggat tggatcctgc
     4681 attacacaag atccaatcct tttcttttac tctagttttt ataatatgtt gaatc
//
LOCUS       DAVMCN010000087         4703 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVMCN010000087 DAVMCN010000000
VERSION     DAVMCN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4703
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.088"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            152..1330
                     /locus_tag="VYP85_001938"
     CDS             152..1330
                     /locus_tag="VYP85_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1882394.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1558..2004)
                     /locus_tag="VYP85_001939"
     CDS             complement(1558..2004)
                     /locus_tag="VYP85_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882395.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDNISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            2074..2733
                     /locus_tag="VYP85_001940"
     CDS             2074..2733
                     /locus_tag="VYP85_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1882396.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2785..3936)
                     /locus_tag="VYP85_001941"
     CDS             complement(2785..3936)
                     /locus_tag="VYP85_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1882397.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3951..4682)
                     /locus_tag="VYP85_001942"
     CDS             complement(3951..4682)
                     /locus_tag="VYP85_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882398.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
BASE COUNT         1460 a          923 c          695 g         1625 t
ORIGIN      
        1 tttgtgtaaa catttgatta ttttttatta tcaatatata ataaaaagag accagtaagt
       61 aatgaaaagc ttaaaaagat taacatctac atttatccat agcaaaaaat cataggattt
      121 taagaatctg acaactagga agaaaactaa tatgacctta tctaagaaac aattacaact
      181 aagagctaaa atactggaaa cagtttacac attaggtccc atttcacgaa ttgaaatcgc
      241 tactaaaaca ggaataacac ctgcaacaac tagcagtatc acaaatgatc tgattaaaga
      301 aaatattctc ttagaacttg gtgaagacga acacgataca agcgtaggga gaaaaaaaat
      361 cctgctagac attcaagcta aacgatttta ctacattggt tgtgaactat ctgaaaaaca
      421 tttcactttt gctttaggag ataatctagg aaatatctta aaggaagaga aagaaattgt
      481 tactaaacag ttaatccaag aaaagggaaa tcaactcatt aaccagacac taaagcaatt
      541 cttaaataac tgctctgatt atgaaataga agcaattgga atcgcgctac ctggtcgcta
      601 tttagatgat tataaaataa caacaaacaa tcctttatgg caacatatcg acttagaaat
      661 gattcaatcc cactttgata agcctttgtt tttctctaac aatgttaact gtatggctat
      721 aggtaaacgc ctatttagtc gccaacagaa tgaccctaat tttgcttatt ttcattttgc
      781 tagaggtatg cactgttctt atatctacga cggaaacatt tatggaaaag gaaatctaat
      841 gattggagaa atagggcata cagttgtttc atctgaggga gaagaatgta gctgcgggcg
      901 caagggatgc ttacaaactt ttgctggaga atcttggtta atcaaaaaat caaaaattct
      961 atatcatcaa tctccctatt ctctacttcc tagtttagtc aaaaatgccg atgatattga
     1021 tatccaagtt attttaaccg cttatcaatt aggtgacact ggaataatca cacttatcca
     1081 tcaagcctta ctctatctta gtcaaaccat tttaaatatc agtatgatga ttgactctca
     1141 aaaaatctac ctacatagtc ctttactaac aaatcaacac atcatccaaa aactatatag
     1201 tgaaatgaac tacaaaccca aactgctcta taatcgccta cctgaagtca ttattgaacc
     1261 ttacaatgat tttacagccg cacactcagc tattgcactt tgtttgtatc atacaattct
     1321 acattcttaa ttttctatta catttaataa ataggctaaa aagagggagt atatcataaa
     1381 aagcgaataa acctgttttc tgaaaatcag aattctgttt tgttcgcttt ctttatattt
     1441 ggaattatac tcctatctcc catttttcat aatgtatagt aaaatgaaat aataacagga
     1501 cgaatcgatc gggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
     1561 ttctagtttc aatccactat attttcgtac aggtgcttca accatttgaa cgatttcaaa
     1621 tccttctttt tggtaaagat tctgagctct ttgatttgcc tcgaagacat ttagagaaat
     1681 attatctata tcttcatttt caaaggccaa actaacaaat ttccttaaag cctggctacc
     1741 taagccttgc ccctgtttct gggggttgat aaaaaatctc ccgatatgaa gattgctgtc
     1801 ttctagcctg attttctgga taaggcccac aaactcttgt tcatcaaaga ttgaaaatac
     1861 ttcttccaag gcttgaaggg tcagtagaaa aggaatcctt ggtcccatcc attgttcttg
     1921 aaaggatttg cctagggagt tggaccattg gcatacaaat tgagcgtttt ctatactcac
     1981 cttttcttca aaacgaattg tcatcttttc ctcaccatct tatctatgtt tctccattat
     2041 actatttctc ccatttttta cgaatagata agtatgattg atttttattt ttttctcgtc
     2101 gggagcattc tcgcttcctt tcttggtttg gtcattgacc gttttccaga gcaatccatt
     2161 atcagttcag ccagtcactg cgattcctgt cagactcgct tgcgtccctt agatttgatt
     2221 ccgattctct cacaggtctt caatcgcttt cgctgtcgct actgcaaagt tcgctatcct
     2281 gtctggtatg ccctctttga actaggctta ggactcctct ttctgcttta ctcttgggaa
     2341 ttgctttcct tggggcaagt cgtcctaatc accgctggtt tgaccttggg tatatacgac
     2401 tttcaccatc aggaatatcc cttactggtc tggatgactt tccacctaat cctaatagct
     2461 tcctctggct ggaatctggt catggtctcc ttcctcatac ttggaatttt ggctcatttt
     2521 attgatatcc gcatgggtgc aggggatttc ctctttttag cttcttgtgc tctcgtcttt
     2581 agcgtaacgg agttactgat cttgattcag ttcgcttctg cgacgggtat cctggccttt
     2641 ctcctgcaaa agaaaaagga aagacttcct ttcgtgcctt tcctcttact tgctacttgt
     2701 ttgattattt ttggtaagct actacttgtt tgataaattc caatttctgc catatgtact
     2761 ccatgaaatt atttcacagt taaattataa attatttctt ttgtacaaag ggatgatgtt
     2821 atcaaatcga tctgttcttc tatcttcttg atactgatca aaaaatttca tttcgactga
     2881 aaatatttcg cttataaact gtaaacgaat actttgttta gacattatag tcgctagact
     2941 gactagatga ttactcaaaa cgacgtccag aatactcttt actttgcttg gttttttaac
     3001 aaaaatttga tcatccaaag gttcaatcat tttgtaacct ttttgcgcaa tttgacgata
     3061 aaagtaagaa tgttgctttg gagtcaataa tcctaactta aaagctcgat actctaaagc
     3121 ctgtatcgaa acattcaaat ccgacttcaa taaaatataa ctatcaggat tgctgacacg
     3181 cttgccaacc ctctcttcaa atttgactaa aaactcttct tttggcaata aaaaacatga
     3241 tgcaaaataa tttgcttctt gctccaaacg atcgccatct tcattcatat ctttatattt
     3301 atgtaaaaga atatgtccta gctcatgagc taaatcaaaa tttcgacgta cagatgattt
     3361 attcgttccc aacacaatat aaggtcttcc caattttgac catgcgctat aagcatcagc
     3421 ttggccatta attaatcgtt ccacgatata gatgcctgaa cgttctaatt tataaagcaa
     3481 atcatgatta tcttttgaaa tacctaattt ttccctggca taaagagcca attcctcaat
     3541 ggattctccc ttatgataag attcactcac tacattactt aggtcatgaa ttgtaatatt
     3601 aggtataatt acaaaacttt caaaataatc aatcaaacta tctaccttat gtaaatacat
     3661 agtttgaata tctattgttt tccgggttgc taggtctgca tttctaaagg caattacaga
     3721 agaatcaaat cgaatgctct cttcttcctg ttcaaaataa gttaaatcaa catgaaattg
     3781 gttggccaaa tgcattttgg ttgataattt aggtttcgtt tcgttggact caaactgcca
     3841 aatggcttgt tccgttaaat taattctctg agctaattct gctctactta aaccatttaa
     3901 cagccgtaat tctttcaata cccgaccatt aaacatttac atactcctta ctacttttga
     3961 ccttcttgtt tttctattct tggaataatt tcaaaatctt ctgtttccga taattctgaa
     4021 aaattaggaa tatcttgata tttagcttct tcgaaatggt acgaacttga ttgaatatac
     4081 tcagacaaat cttgaatcaa gtgtaactga ccagttcgtg catcaggcat aacaacatct
     4141 acagatataa tattgttttc tgagtccgcc tcataagtta aaatcataaa tttttcgata
     4201 ttcgaatttt tagtagcttg ttcaatttct tgaatcattt catcagaaac taactccatc
     4261 tgaattggaa aggaatgact atcttcatca tttttgtagg aagaatgttg attaagataa
     4321 agtgtattca tctgagcata ttcaaataag tagccactct tatttttttg taccaaagga
     4381 aattggttcg taagtcgctt cttacccttt ataattaaca atactttccc atatttttct
     4441 gtgtttgttt caaattctaa atatccccaa gtctgtcctg ctaattgtaa tttatactca
     4501 aacaaatctg ctgatgcaaa tgcagtatca atatgattag gtcgcgtcca tgcataacca
     4561 ttcgacacta tcattgtctc tcttttttct agacgttcat ctacataatc tttttgccct
     4621 ttcatcaaag tatctacaat tttttgtgcc tcaagcgaat caaagagatc ctgattcaac
     4681 ataattcttc ctcctccaaa tac
//
LOCUS       DAVMCN010000088         4662 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVMCN010000088 DAVMCN010000000
VERSION     DAVMCN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.089"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            128..316
                     /locus_tag="VYP85_001943"
     CDS             128..316
                     /locus_tag="VYP85_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1882399.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            378..1136
                     /locus_tag="VYP85_001944"
     CDS             378..1136
                     /locus_tag="VYP85_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1882400.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            1194..2048
                     /locus_tag="VYP85_001945"
     CDS             1194..2048
                     /locus_tag="VYP85_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1882401.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            2160..3044
                     /locus_tag="VYP85_001946"
     CDS             2160..3044
                     /locus_tag="VYP85_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1882402.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            3207..4334
                     /locus_tag="VYP85_001947"
     CDS             3207..4334
                     /locus_tag="VYP85_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV1882403.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLFEIIKNIKNLVINLN"
     gene            4283..4651
                     /locus_tag="VYP85_001948"
                     /pseudo
     CDS             4283..4651
                     /locus_tag="VYP85_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
BASE COUNT         1556 a          691 c          969 g         1446 t
ORIGIN      
        1 aattttttaa taccaaagat ttaaagttac tgtgttaaaa atcctctcca cttttaaact
       61 aatgtattat aaaagccagt tgacacaagt gttacaccta tgatagaatt aacttgaggt
      121 gatgaaaatg gcaaccgata aaaatagaat aatgattagc ttggatgata aaaatctaga
      181 gaaacttgaa aatttagtag aagatgctag agatagaagg ggaatgcgac taacaaagtc
      241 ccaggttatt gaattactcc taaataccgt tgattatttc gatgatatta tgggggctat
      301 ttactcaaaa aaataagagc aaaattgcta ttatttttta caaattggtg taacactagt
      361 gatataggag tgatgaaatg gttgtttata ttagacaaag taaattacca agtgaggttt
      421 caattaataa atacaatgct caagtaggtg cctacttaca aggagaagaa gttattttat
      481 atcaatcttt ttctgaaata aaagagttaa caagtgaaga tatagttgta gattatataa
      541 tggagactag agcattacta aaaatgatgg gcttaaacgt tccggttcat gactatccta
      601 ttgagcttaa agagttttat ggtcgaaaga tttatgctgg tattttagga gagattgtga
      661 atatacctga taattgggga aaatttatta agcctaaagc tggttcaaaa gtctttactg
      721 gaagagttgt taatggaacc catgatttaa taggtattgg tctacctttc gactatccta
      781 tatggattag tgaggttgta gaattcatag ctgaatggcg ttgttttgtg ttagatggtc
      841 gcgtattaga tgttcgaccc tatacaggtg attatcatgc acaatttgat gcaagtgtaa
      901 ttgatgaagc gatatcatgt tggaaagatg cgccaatagc ttatggacta gatatcggtg
      961 ttactcgcga tggcagaaca cttgttgttg aagtaaatga tggttatgca ttgggaaatt
     1021 atggcctatc tcctttaaaa tcaatcaatt ttcatagagc taggtggaaa gaaatggtaa
     1081 aaccctattt tgaaaaaaat gaaattttta aaatccaaca ggatgttatt ttctaaaata
     1141 aatatggtag ataaccaata taaaaagcat caaaatgaac aaggaggaat ctgatgcttg
     1201 gagcaattat tggagatatt gtcggttctg tttacgaatg gaacaatatc aaaacaaagg
     1261 actttccttt atttcggaag gactgctttt ttacagatga cacggttatg acctgtgctg
     1321 ttgcagaagc aattatgaat ggtggacaaa aagacgactt cattgacgcg atgaagaaat
     1381 atggcagaat gtatccgaat gctgattacg gtgctcggtt taatgcatgg ctaaacagcg
     1441 ataaccgtga gccttataat agctttggga atggatcagc tatgcgtatt tctccatgtg
     1501 cttggatcat ggactgtggt ttttatgcga aaactggtat atggccatca tctagaggac
     1561 ttacgagtct ttctgcagag gtaactcata atcatccaga aggtgtcaaa ggcgctatgg
     1621 ctacagctga tgctatcttt ctatgtcgtt tttactttgg tggttattgt agagagtacg
     1681 agcaatcaat taacgacaat cctacagagt gtaaaagacg aattaaggat tatatagaaa
     1741 aagaatacga ttacaatcta tctcaaactt tagatgaaat ccgtcctaac tatcgtttta
     1801 acgaaacatg tcaggaaact gtccctcaag ccattatcgc ctttcttgaa agtagagact
     1861 tcgaagatgc gataagaaat gccatctcac ttggtggcga cagtgatact ctcgcagcaa
     1921 tcacttgtag catagcagag gcagcttacg gtattcctga ttggatcaag gataaggcct
     1981 attcttactt ggatgaaccc ttaaaggatg tagttaggcg atgggaaaat agaataaaag
     2041 cgtattaatc tccagtacgt cagatttctc ttttctgtat tttcattgta taataggatt
     2101 acatttactt gcatacgacg aaatgtaaac atttctgttt aaaattaagg ataaaatcaa
     2161 tgaaaaaagc aatggtaatt atcaacccta cttctggtgg cgagaaggct ttggattaca
     2221 aagaaaagct ggagaataaa gcaaaagaat actttgaata tgttgaaacc aaaattaccg
     2281 aaaaagcgct ggatgcaaca cattttgctg aagaagcttc tcgtgagcag tatgatgcag
     2341 tggttgtgtt tggtggagat ggaactgtca atgaagtcat ttcaggtatt gatgagagag
     2401 actacattcc taagttaggg attatcccag gcggtacggg taacctcatt acaaaacttt
     2461 tggaaatcaa tcaagacatc gatggcgcaa ttgacgaact ggattttgat ttaaccaata
     2521 agattgatat cggtaaagca aatgacaact attttggtta tatctttagt atcggttctc
     2581 tgcctgaggc gattcacaat gttgaaatag aggacaaaac aaaattcggt attttaacct
     2641 atgctgtaaa taccatgaag tctgtcatga cagatcaggt ctttaacatt aaggttgaga
     2701 cagaaaatgg aaattatgtt ggtgaagcta gccatgtttt ggtccttttg acaaattact
     2761 tcgctgataa gaaaatcttt gaagaaaaca aggacggcta tgccaacatt ttgattctga
     2821 aagatgcctc tatattctcc aaattatccg tcattcctga tttattaaaa ggggatgttg
     2881 tcgcaaatga taatatcgag tatatcaaag cgcgtaatat taaaatctct tcagatagtg
     2941 aattggagtc agatgttgac ggagataaat cagataacct acctgtagaa atcaaagtcc
     3001 tagctcagcg agtagaagta ttttcaaaac cgaaagagga ttagtatata gagaaagcct
     3061 tttttaaggc tttttgtata ctttaaaaga tagttccttt aacaacggac attccttgca
     3121 aatagtttac aaaaatagta tactggattt attgagtttg aaaacgtttg cgtaaaattt
     3181 gaatgaatac tttaggagac aaattgatgg aattgagtgc tatttaccat aggcctgagt
     3241 cggagtatgc ctatctttat aaggataaga aactccatat tcgaattcga actaagaaag
     3301 gggacattga aagcatcaac ttgcactatg gggacccttt tatctttatg gaggagtttt
     3361 atcaggatac aaaagaaatg gtcaagataa cttctggtac cttatttgac cattggcagg
     3421 ttgaagtgtc agttgacttt gcacgtatcc agtatctctt tgagctcaga gatacagaag
     3481 gtcaaaatat tttgtatggc gataaagggt gtgtggaaaa ttctctagaa aatcttcatg
     3541 caattgggaa tggatttaag ttgccttatc ttcatgagat tgatgcctgc aaggttcctg
     3601 actgggtttc aaatacggta tggtatcaga tatttcctga aagatttgcc aatggcaatg
     3661 ctctattaaa cccagaaggg actttagact gggattcatc tgtcacacct aagagcgatg
     3721 atttctttgg tggtgattta caggggatta ttgatcatat ggattacttg caagacttgg
     3781 gtattactgg actatatctt tgtcccatct ttgaatctac aagcaatcac aagtacaata
     3841 cgacagatta ctttgaaatt gaccgtcatt ttggagacaa ggagaccttt cgggaactgg
     3901 tggatcaagc gcatcatcgt ggcatgaaag tcatgctgga tgcggtattt aatcatattg
     3961 gttcgcaatc tcttcaatgg aaaaatgtcg tcaaaaatgg tgaacagtct gcttataagg
     4021 attggttcca tattcaacaa ttcccagtga caactgaaaa gctagttaat aagagagact
     4081 taccctatca tgtttttggt ttcgaggact atatgcctaa gctaaataca gccaatccag
     4141 aggtcaagaa ttatctttta aaggttgcga cttattggat tgaagagttt aatatcgatg
     4201 cttggcgttt ggatgtggct aatgagattg accatcagtt ctggaaggat tttcgtaagg
     4261 cagttttagc taaaaatcct gatcttttcg agattataaa aaatataaag aatctagtca
     4321 taaatttgaa ttgaaacaac gtctttattt tttgcttcag caatctaaat cgtttgatga
     4381 ttttttagag aaagcaaagc agttgcatgt tcagattgat tttagtcaaa agcatagccg
     4441 ttttttgatg acagatagaa cgatgataaa accaattcga gggcgccaac tcagcaaacg
     4501 agatctatat gatgaagaat tttttagaac gcattttgct aagcaagaga ttgaaagtcg
     4561 tttagaattt ttgttaaacc gtgtcaattc tttagaagat ttaataacaa aagcaaaaga
     4621 attgaatcta accattgact taaaacaaaa aatgtaactt tt
//
LOCUS       DAVMCN010000089         4651 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVMCN010000089 DAVMCN010000000
VERSION     DAVMCN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.090"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(208..279)
                     /locus_tag="VYP85_001949"
     tRNA            complement(208..279)
                     /locus_tag="VYP85_001949"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(244..246),aa:Arg,seq:cct)
     gene            complement(321..668)
                     /gene="rplS"
                     /locus_tag="VYP85_001950"
     CDS             complement(321..668)
                     /gene="rplS"
                     /locus_tag="VYP85_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1882404.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(787..1116)
                     /gene="crcB"
                     /locus_tag="VYP85_001951"
     CDS             complement(787..1116)
                     /gene="crcB"
                     /locus_tag="VYP85_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1882405.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1110..1484)
                     /gene="crcB"
                     /locus_tag="VYP85_001952"
     CDS             complement(1110..1484)
                     /gene="crcB"
                     /locus_tag="VYP85_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1882406.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(1481..1747)
                     /locus_tag="VYP85_001953"
     CDS             complement(1481..1747)
                     /locus_tag="VYP85_001953"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1882407.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(1863..2306)
                     /locus_tag="VYP85_001954"
     CDS             complement(1863..2306)
                     /locus_tag="VYP85_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1882408.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2410..3345
                     /locus_tag="VYP85_001955"
     CDS             2410..3345
                     /locus_tag="VYP85_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1882409.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3399..3683
                     /locus_tag="VYP85_001956"
     CDS             3399..3683
                     /locus_tag="VYP85_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1882410.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3740..3958)
                     /locus_tag="VYP85_001957"
     CDS             complement(3740..3958)
                     /locus_tag="VYP85_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882411.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(3955..4526)
                     /locus_tag="VYP85_001958"
                     /pseudo
     CDS             complement(3955..4526)
                     /locus_tag="VYP85_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1447 a         1011 c          823 g         1370 t
ORIGIN      
        1 tatagtcctt taaataattt agaacttgac gattttgaat aaattgacta tacaaacatt
       61 tatatactcg atatagtctc aattttatct gatgattgcc caaatttttc aataataaaa
      121 cgcataatat tatggagaca atcccctata ttatgcgttc ttttaatatc aaagactttt
      181 tgacaaactt cttcgatatc taattactgc cccctgcagg aatcgaacct gcaactactc
      241 cttaggaggg agttgttata tccattgaac taagggagct agataaaaac tctgctgaaa
      301 agcagagttt tttagtcgaa ttaacgacgg atttctttga tacgagctgc cttaccttga
      361 agagcacgca agtagtacaa tttcgcacga cgtactttac cgtaacgaac aacttcgatt
      421 ttttcaacac gtggagtgtg gattgggaag atacgctcaa cacctacacc gttagagatt
      481 ttacgaactg tgtagttttc tgagattcca gcacctttac gtgcgataac aacaccttca
      541 aaaatctgga tacgttcacg gttaccttcg acaactttcg catgtacacg aacagtgtca
      601 ccaggacgga atgatgggat atctgtacga agttgacctt cagtcaagct ttggattaat
      661 ggattcattt tattctccta tctttgtcaa tcttgaggaa tcttcctcag cggataaact
      721 gtatttttgt gcgtccatta cacacaagat atagtttacc aaatttctaa aaaaaagtaa
      781 agaaatttat agcaaaattc ctaaaaaaat cgcaaccaaa ccacctatgt aagtcaaagt
      841 caggtaagaa taaaagacct tcttatcact tagcagtctt tgaagttcgt cattcaaggt
      901 cgaaaaagtt gttaaaccgc cacaaaatcc tgttgctaga atagcatata cttccttaga
      961 ctctacatga ttgtagaata ctccaattaa aaaacaacct aaaagattag ctatgagcgt
     1021 tccgagtggc aatttagaag cttgattata gcgagaaaag aaataccgta cgagtgctcc
     1081 caagccacag gcgattgcaa gatagacgat taccatttct tcctccccaa atagtaagct
     1141 aaaagcaggc ctccaccgat actcaaaagc aaatacagta tcaaactaag ataacgccct
     1201 gtatcaagca gcttcacagt atcaagcatt aggctggaaa aagttgttaa acctccgcaa
     1261 aaacccgtcc ccagtgctaa aatcaagccc ttactagtcc ccttatagac cagatagccc
     1321 ttgacaagat aaatcaagca gaaaattccc agatagttga caaagagagt gccccaaggg
     1381 aaatctggac tggctggtaa ccaagtggaa actaggtagc ggacaagtcc gcccaacata
     1441 gcagctagaa aaatccctag cggataaaat tgttcttttt tcatttgata ttttgatcct
     1501 gataatcacg cgaacgtttg agtatgtccg aaaaagtcgc gacaatagtc tcctgatagc
     1561 gcttgtcctc tacacgactt ctaacctttt caaaaataac tgcttctctc ttagtatcta
     1621 aaatcggttt ccctgaagcc ttcttataag cgacaactcc ttcaactaag tgcattcgtt
     1681 cttctaacag tttgacaatt tggtcgtcga tttgatcgat ttcttgacga ataatatcta
     1741 aatccataca gtctcctcct ttatttgaat tattgtatca aaaagccatc aattaggcta
     1801 gtaaaatccc aactctcgat aagaaaaatg cactgattga ttacatcagc gcacttttat
     1861 gcttatccta ctttagcagc caattcttct gcgaattgtt ccaagcgttc aatatcttct
     1921 tcctcggcag aaagatcaac tttaacacac tctgaacctt tttctgctcc tgttgacaca
     1981 aagacacggt caaagtcatc aacagcctta caaaattcat cgtagaaggt atctcctgag
     2041 ccgaccactc cgtagatttt gccattcaag ttgagatctg ctaggtcttc gtagaagtcc
     2101 atcatctcat ctggcaattc accatcacca taagtatagg tcgcaacgat agcgatgtct
     2161 gcttccaaga agtctgaagc gtcaacagtt gtacattcat caacatcaac atccaagccc
     2221 aagtcacgta atttgtctgc tacaatatct gcaatttctt cggtattacc ggtcatactg
     2281 gcaaatacaa tttttgctaa tgccatatcg tcctcctcaa tttatctttc tccattatat
     2341 cacatctttt tcattttaaa aataaaaatt cttgtgctac aatgaaatga gaaagaattg
     2401 aggttattta tggagatttg ccaacaaatt ttagaaaaaa ttaaagaata cgacaccatt
     2461 atcattcatc gtcatatgaa accagaccct gatgccttgg gaagtcaggt gggattgaaa
     2521 gccttgctag aacatcattt cccagaaaaa accatcaaag ccgtcggttt tgatgaacca
     2581 actcttactt ggatggctga gatggatctt gttgaagata gagcctacca aggcgcactt
     2641 gtcatcgtct gtgatacagc taatactgct cgtatcgatg ataagcgcta tagtcaaggt
     2701 gattttctca ttaagattga ccaccatcca aatgatgatg tatacggtga cctgtcttgg
     2761 gtcgatacta gttcaagtag cgctagcgag atgattaccc tatttgccca aacaacccaa
     2821 ctagccttgg cagatcgcga tgctgagttg ctctttgcag gaattgtcgg tgatacaggt
     2881 cgcttcctct acccttctac cactgcacgg actcttcgcc tggctgctta tttgagagaa
     2941 cataactttg actttgcggc tctcactcgc aaaatggaca ctatgagcta caaaattgct
     3001 aaactgcaag gctacatcta cgaccatctg gaagtggatg aaaatggtgc tgctcgcgtt
     3061 atcctgagtc agaaaatctt gaaacaatac aatataaccg atgctgaaac tgcggccatt
     3121 gtaggtgcac ctggacgcat tgacagagtg agtctctggg gaatttttgt cgaacaggct
     3181 gatggccact accgagttcg cttacgcagt aaagtccatc ctatcaatga aattgccaag
     3241 gagcatgatg gtggaggcca ccctctagca agtggtgcta attcctatag cctagaagaa
     3301 aacgaaatca tctaccaaaa gttaaaaaac ttgcttaaaa actgataaaa tacttgccaa
     3361 acttttcaga atctgataga ctagtatagt aacaatctat ggctcgcaaa gagaccatgg
     3421 cagaaaggaa atattgcaaa atgaaaaaag atatccatcc agaatatcgc ccagttgtct
     3481 tcatggacac aactactggt taccaattcc ttagcggttc aacaaaacgc tctaacgaaa
     3541 cagttgagtt cgaaggcgaa acttacccat tgatccgtgt ggaaatttca tcagactcac
     3601 acccattcta cactggacgt caaaagttca ctcaagcaga tggacgcgtg gatcgtttca
     3661 acaaaaaata cggtctcaaa taatgataag agaacagttt tggctgttct tttttgtttc
     3721 ttgaaatcaa ctgctgtttt catgttccag actcatctgt aggttcgatt tccatgctac
     3781 taggcaggaa ggaaatagct gtttcaacac gtccataatg agctatacta ttgtcacgaa
     3841 ccacactttc attgatggtc caagtggaat tcattttctt aaaagcttct cggacttttt
     3901 ccaaatcttt ggaggcaatg gcctgctcta aggtttcaaa acgaggactt atactcatct
     3961 gctttcaaaa agcattctag tccatctccg attaccgatg gactttatca cctccttctc
     4021 cagtccttgt atgacatctt gaagttgatt catgacatct tccaaagttc gaaaggcttt
     4081 attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatgggtt catctctggt
     4141 gtgtatggag gaataaaggt aaaatcaata ttagtcggaa tatttaaggt acttgattta
     4201 tgccatatag cattgtccat aacgagtaaa aggataagct tgtgaaagct cttctaaaaa
     4261 ggcgttcatc cacactcctt tttataaacc tgaaataagg catcaattgt aacaaattct
     4321 cctgcctctg tagccttcaa atgacgggca agaaaggctt tctcttcctc aactgtcata
     4381 tatgcatggt tacgaccacc acgtgtttct tgaaggagag agtcgagtcc gaactcctca
     4441 tattttttta cgtttcgcca aatcgttgtt tgattacagt ctaaaagctc tataatctct
     4501 ttataagatt tgcccatcag acgaaatata gtagattgaa actagaatag tacacctcta
     4561 cttctaaaac attgttagaa atcgatttgt cctgttcttg tttcatttta ctatagaacg
     4621 atttgaaggc gtttataata tttagctgta c
//
LOCUS       DAVMCN010000090         4621 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVMCN010000090 DAVMCN010000000
VERSION     DAVMCN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.091"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(347..898)
                     /locus_tag="VYP85_001959"
     CDS             complement(347..898)
                     /locus_tag="VYP85_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882412.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWA
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1248..2072)
                     /gene="nadE"
                     /locus_tag="VYP85_001960"
     CDS             complement(1248..2072)
                     /gene="nadE"
                     /locus_tag="VYP85_001960"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1882413.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2069..3529)
                     /locus_tag="VYP85_001961"
     CDS             complement(2069..3529)
                     /locus_tag="VYP85_001961"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1882414.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGAQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3645..4133)
                     /locus_tag="VYP85_001962"
     CDS             complement(3645..4133)
                     /locus_tag="VYP85_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882415.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4123..4332)
                     /locus_tag="VYP85_001963"
     CDS             complement(4123..4332)
                     /locus_tag="VYP85_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1882416.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT         1326 a         1055 c          855 g         1385 t
ORIGIN      
        1 agactatttt aatattagat aatttgatag aaaaaacata aataaaattg gttgaattta
       61 attccctaac tcgatagagg attctatttt aaatttaaca acagctagga ttacactata
      121 aaaagtacat taccacctgt tcggctggag aatctagtcg attagctccc tcttagttac
      181 aagcttaaag cgatttttta actaatacta aaccagatta aagaaggaac tagaacatct
      241 gtcttgtact aatcaatatg ctattttaaa attgcaaata aacttggaat gctaattatt
      301 atatttacaa taaatagttg acttcgatag aaacagaaaa tagaattcaa cattcttccc
      361 tacttatacc ataataaata agatccgcaa gatagccttt tctctctaca ccattaacaa
      421 tggtttgtag ataggacatt ccagcctttt ccatgacacg acctgaagct gggttgagac
      481 tggcataacg tgctctgacc ttttgaaaac ctgcttgagt aaaacaaaag tccaagacag
      541 ctttcaaggc ctctgtcatc ataccatgtc cccagtaagc cttgcctagc acatagccga
      601 tttcacagct taaatcagcc tcgtctatct taacgatgct gatatctcct atcacttgct
      661 ctgggttttc ttttagacaa atggcccatt tgtaatagtt gagattagta taggaagcaa
      721 cccaattgcg aatcgagttt cgagtgattt cgacatcagg atggggagcc caggtaacat
      781 aggtcagatt ctcagcggat gaagcccaat tttgaaacat ggcttctgca tcactctcca
      841 caaatcttct taaaatcaaa cgttctgtct gtaatatttg cgtaccaata gatttcatga
      901 tgctacctca cttccttatt tctatgctcg tagtaaaaag gctcaactca gtaacagcta
      961 gaaaacgagt ttgtcttcta atttcttgac gcagtcgctg cctggtttga aatgcgatct
     1021 agcaagcttt ttcaaaccta gtcatcgttg caggggtaag acgatgaaat cgaactcttc
     1081 gagttaccga atctgcctca ttttcttatt tctaaactcg aggttcaaga tcccccggac
     1141 cttctctcac tttcttattt caagatgaga ggctgaaaac ctccagtgga ggtttttctt
     1201 gctttttaat ttcagggcaa gaagctaaaa aggtcccccg gaccttttta ctcccaaaag
     1261 tcatcaaata cggtgatggg taagtggcgt ttgtgttggc ctttgtgcca ccagttttca
     1321 atggtcgctt gagcttctgg gctgattgtt ttgccttcta ggtagtcgtc aatctctgcg
     1381 taggtgactc caagtgcgac ttcgtcagct aggcctggtt tatcttcttc taggtctgcc
     1441 gttgggattt tttcataaag ggctggctct gcgccaagtt tctgcaagag ctgttttcct
     1501 tggcgtttat tgaggcggta aagagggaga atatccgcac cgccgtcacc aaacttggta
     1561 aagaaacctg tgatattttc tgcggcgtgg tctgttccaa tgaccgctcc gctatgggaa
     1621 ccagcaaggg catactgagc aatcatacgg caacgtgcct tgatattccc cttgttgaag
     1681 tctgaaacag gactacctgt cgcttcaact gcagctgtca tggcatcagc tgattccttg
     1741 atattcacaa ccaagctgac atctggctgg atgaaggcta gggctttttg agcatctgct
     1801 tcatcagctt gcactccgta tggcaggcgg acagcgataa atttgtagct atcgtctccc
     1861 gtttcagctc gcagttcttc catagctaat tgcgccaaac gtcctgccaa ggttgagtct
     1921 tgtcccccag aaatccctag tacaaaggtt tttaggaagg gatgtttttt cagatatctt
     1981 tttaagaaat caatagaacg acggatttct tcctgggcat caatcactgg tttgacaccc
     2041 agctcttgga taatcgtttc ttgcaaactc attcttcttc tccttcacca agggcttcct
     2101 tgcgcatctt atcaatcaag tccatcttat cttgccatac gtcacgcgcc aaatccactg
     2161 gatagtgctg cggattgagc acacgcttat actcatccca caacttgtca aattccttac
     2221 gggcataatc ctgaatgtca gtcaaactag gcaagttgta aactaatatt ccttctttga
     2281 agatatccac caagagagga acggcatcaa aattacgaac cgtcttcttg atgtatgtat
     2341 aggtcggatg gaacatcttg atttctgtca tgtcgctaat atccacacca tcataagtga
     2401 tgtagtcacc ttctgacttg cctttttcac gactggtaat gcgccacacc tgcttcttac
     2461 ctggcgtaga aactttttca gcattattag acagcttaat cgtattgcgc atctgaccag
     2521 tttcatcttc gattgcaaca atcttgtaaa ctgcaccaag agctggctgg tcataagctg
     2581 taatcagctt ggtacccacg ccccagacat caatcttggc cttttgcatc ttgagattga
     2641 ggatagtatt ttcgtccaaa tcattagaag cataaatctt agcctctgta aatccagcct
     2701 cgtccagttg ctgacggact ttcttagaaa tgtaggcaat atccccagag tcaatccgca
     2761 cacccataaa gttaatctga gcacccagct cacgcgccac ctgaatggca gctggtacac
     2821 cgatgcgaag ggtgtcatag gtgtccacaa gaaagacaca atttttgtgg gtcgcagcgt
     2881 aagccttgaa agcttcatag tcattgccat aaacctgtac caaggcatgg gcatgggttc
     2941 ccaaaacagg aatgtcaaag agcttacccg cacgcacgtt gctggttcca ttggccccac
     3001 caatcaccgc tgcgcgtgtt ccccagatgg ccgcatccat ttcttgagcc cgacgtgtcc
     3061 caaactccat caagggttca tcttcgataa ccgaacgaat acgagctgcc ttcgtcgcca
     3121 ccaaggtctg gtagttgacg atgttcaaaa gagccgtttc gaccaactga cattgggcta
     3181 gaggtccttc cacctgcaca atcggttcat tagcaaaaac caaatcccct tcttgggcag
     3241 aacgaacggt caactccaac ttgaaattgc gaaggtaatc caagaacgcc ccatgataac
     3301 caagcgactc caaataggct atatcactat ctgaaaaacg caagtcttca agatagttca
     3361 caattctttc caaacctgca aaaaccgcat agccgttctt aaaaggctgt tggcggaaat
     3421 acacctcaaa gaccgccttc ttattgtgaa tcccttggtc aaagtaaacc tgcatcatgt
     3481 tgatctggta caagtccgtg tgcaatgtca aactatcatc tggatacata cttttcctac
     3541 ttccttagct agaaacacat gaaaattttc aagaactttc atgtattcca ataaattagt
     3601 actattatat cacattttag ctggattgag aaaagagtaa caagctattc tccactctcc
     3661 aattcatcca tatcttgttc aaattttttc tgagcccatt cgccatagct cttaagacca
     3721 agattgccaa taaagaccca cggaaggtaa atgacataag taatgaccca agcagacagg
     3781 tatttaaaat tcaaaggatt gtgctgataa atttctatgt tgaattgata attctgcaac
     3841 atcaaaagag ccgtaatagc caaggttagg aaaaaacaac ccaaaatcgt aaaatgaaaa
     3901 cgactatagt aggtcactcc cagataacgg gcgcgattga aaaagtaaaa tgtccctatg
     3961 atgataacga ttagcagcat attagaatta aaaaggcttg gtgctaatac tgaaatgata
     4021 taagatagga gcgacaaagc aatgcagata tagaaacttt cagatcccgc tttattgaac
     4081 agttgttctt ctctttcgtc tagtaattga taataataaa atctattttt catcttcttc
     4141 ctcccaaaat agttggtcta gggttttccc taaacatctg caaatagact ggcagagcga
     4201 gagactggga ttgtattttc ccgcctctat caaaccaata gtctggcgtg tcaccccgac
     4261 agcctctgcc agttgacctt gtgttaaatc acgctctacc cgagctaatt ttaattttaa
     4321 atttttagcc accttcgtcc tccttatagt tttaatactc atctactctt aaaaaatcca
     4381 aaaccaacac aagctatcag ctatttatta taaccccatt aatttgcact ccagtattat
     4441 cttcagccga aaatcagtat tttaggttgt ttgaaataaa cttcctagtt tactctttta
     4501 tttttattta gtattagctt tagtagaatc ttttaaacga gtttttattg cttatatttc
     4561 ttgtttagtt tagttggttt catatcacta ttatataatg cttttggaaa tgagcctagt
     4621 a
//
LOCUS       DAVMCN010000091         4336 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVMCN010000091 DAVMCN010000000
VERSION     DAVMCN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.092"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            138..947
                     /locus_tag="VYP85_001964"
     CDS             138..947
                     /locus_tag="VYP85_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1882417.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            952..1653
                     /locus_tag="VYP85_001965"
     CDS             952..1653
                     /locus_tag="VYP85_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1882418.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1678..2595
                     /locus_tag="VYP85_001966"
     CDS             1678..2595
                     /locus_tag="VYP85_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV1882419.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2623..4164
                     /locus_tag="VYP85_001967"
     CDS             2623..4164
                     /locus_tag="VYP85_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV1882420.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4183..>4336
                     /locus_tag="VYP85_001968"
     CDS             4183..>4336
                     /locus_tag="VYP85_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1882421.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCM"
BASE COUNT         1428 a          646 c          835 g         1427 t
ORIGIN      
        1 tatattttta tgtttgttgt tctgttatga aacgaaagaa attggaaact agtttctaat
       61 ttatgaaaaa tattgaaaaa aaaaaaaaaa gtgttaaaat aaagaatgta aacgtttact
      121 tcaactaagg agctcatatg ttactgcaaa aagaactaat tccaatgata gaagctaact
      181 taccaaatat ggcatatgct gaaaaagaca ttgctaaatt cttcttaaaa cagcaacctc
      241 tgaatgatta ttcatctaaa gcattgtgcg aataccttaa tgtatccaaa gcaacattga
      301 ctcgatttgc gaaaaaatgt ggttttaaag gttttagaca attcattttc aaataccaag
      361 agatgattca tgagaaagaa aagttggcat tatatacaga ggcaacagaa aaagttttat
      421 ccgactatga ggaaatgttg agaaaaactt acacggttct tgatgaagtt caacttgagc
      481 gtattgctga gatgatagaa actgctgagc gtgtatatct ctacggtaaa ggaagttctg
      541 ttcttgcttt acaagaaatg aagatgagat ttatgcgtct cggagtgatt ggtgaagtat
      601 tatcagacga ggatatgatt ttgtggagta gcttactact taatgaaaat tgccttgtca
      661 ttggagcatc catttcaggt caaactgata ttgtactaga aggtctacaa aaagctgcag
      721 ataaaggcgc taaaacagtt ttaatgacta caagaaaatt tgacgaagaa gattgtttct
      781 ttgatgaact attgttatta gcttcgaccg atcatctctc gtatggcaat cgcatatcac
      841 ctcagtttcc aatactttta attacagact gcttattctc taattatctg gaaagtccag
      901 agagacaata ttattacaat caaactatta tccataagga ggaataataa aatgagccaa
      961 atttggacta aagaaaaatt tataagccaa gttcaaggtg gagtcattgt ttcttgtcaa
     1021 gctttacctg gtgaagccct ttataatgaa gaatttagct tgatgccttt tatggctaaa
     1081 gcagctttag aggcaggagc agtgggcatt cgcgcaaatt ctgtgcgtga tattaaagca
     1141 attcagaaag tagtagattt accaataatt ggaattatca aaagggatta tccacctcaa
     1201 gaaccatata ttactgctac gatgaaagaa gtagatgaac ttgtagaatg cggaacaaca
     1261 gtcattgcat ttgatgcaac tttaagacca agatatgatg gcttagttgt cagtgaattt
     1321 atcaaaaaaa taaaagaaaa atatccgaat caattgctga tggcggatgt aagtaattta
     1381 gatgaaggtc tctatgcatt taaatcaggc gttgattttg ttggtacaac attatcaggt
     1441 tacacaagta caagtgtaca atcagatgag cctgattttg aactaatgaa aaaattggct
     1501 gattttaata ttccggtaat tgccgaagga aaaattcatt atccagaaca attaaaaaaa
     1561 gcttatagtt taggtgttac cagtgtagtc attggtggag cgattacacg tccaaaagaa
     1621 attgctcagc gatttattaa tgtcatcaaa taaaaaacaa tataaaggag aaatctgatg
     1681 aaagatttaa ctaaatacaa aggcgttatc cctgcatttt atgcttgcta tgatgaaaat
     1741 ggtgaaatta gccaagatcg tgtaaaatct ctggtacaat atttcattga caaaggtgta
     1801 aaaggtatct atgtaaatgg ttcttcaggt gaatgtattt accaaagtgt agaagatcgt
     1861 aaacaaatta ttgaagctgt tatggaagtt gctaaaggta aattaacagt tatcaaccat
     1921 attgcatgta ataacacgaa agatagtatc gaattggcaa aacattcaga aagtgttgga
     1981 gtcgatgcta ttgcagctat cccacctatt tatttcaaat tgccagagta ttcaatcgca
     2041 gcatattgga atgcaatgag tgaagctgcg tcaaatacag attttattat ctataatatt
     2101 ccacaattgg caggggttgc gttgactggt agtttgtatg caacaatgcg tcaaaatcct
     2161 cgtgtgattg gagttaaaaa ttcttctatg cctgtacaag atattcaaat gtttgtagct
     2221 gcaggtggag aagattacat tgtattcaat ggtccagatg aacaatatct tggtggtcgc
     2281 ttgatgggag cagaagctgg tattggtggt acttatggcg ttatgccaga tttgttcttg
     2341 aaattggaaa gtttgattca agaacgagat ttagatacag ctaaaaaact tcaatatgct
     2401 atcaatgaag ttatctataa gatgatatca ggtaaggcaa atatgtatgc tgtagcaaaa
     2461 gaagttttgc gtctaaatga aaaacttgat ttaggttctg ttcgtcaacc tttagaagca
     2521 ttggcagaag gtgacttgga agttgcaaaa caagcagcag aacttattca acaagcacga
     2581 aaagaatttt tataataaat aaaatcaata tggagatatg ttatgggcac aacaggattt
     2641 acaataattg acttaattat cttgattgtt tatttacttg cggtgttggt tgcaggtatc
     2701 tatttctcta aaaaagagat gaaaggaaaa gagttcttta aaggagatgg ttcggttcct
     2761 tggtatgtta cttcggtatc catttttgcc acaatgctca gtccgatttc cttcttggga
     2821 ctcgctggta gctcttatgc aggtagctgg attttatggt ttgctcaatt agggatggta
     2881 gtagctattc cactgacaat tcgttttatc ttacctatct ttgcacggat agacatcgat
     2941 acggcatatg attacttgga taaacgtttt aattctaaag cacttcgtat tatttcagca
     3001 ctcttgttta ttatttatca attgggacgt atgtctatca ttatgtacct cccatcagct
     3061 ggtttatcag tattgacagg aattgacatc aatattttga ttattttgat gggtgtagtt
     3121 gcaattgttt attcttatac tggtggtcta aaatccgtat tatggacaga ctttattcaa
     3181 ggtgtgattc tgattagtgg tgtcgtttta gctttatttg tactgattgc taatattaaa
     3241 ggtggctttg gtgcagtagc agaaacatta gcaaacggga aattccttgc tgcaaatgaa
     3301 aaacttttcg atcctaactt gctttcaaac tccatctttt taattgtgat gggttcaggc
     3361 tttacaatct tgtcttccta tgcttcatct caagatttgg ttcaacgttt tactacaaca
     3421 caaaatatta agaaacttaa taagatgttg ttcacaaacg gtgttttgtc acttgcaact
     3481 gcaacagtct tttacttgat tggtacaggc ttgtacgtat tctatcaagt acaaaatgca
     3541 gatagtgcag ctagcaatat ccctcaagac caaatcttta tgtactttat tgcataccag
     3601 ttaccagtag gtatcacagg tttgatcttg gcagcgattt atgcagcatc tcaatcaact
     3661 atttcaacag gtttgaactc tgttgcaact tcatggacat tggatattca agatgtcatt
     3721 tctaaaaata tgtcagacaa tcgtcgtacg aaaattgcac aattcgtatc tctagcagta
     3781 ggtttattct caattggtgt ttccattgtc atggctcact cagatattaa atctgcatac
     3841 gaatggttca atagtttcat gggacttgta cttggtctac ttggtggtgt atttattctt
     3901 ggatttgttt ctaaaaaagc aaataaacaa ggtgcttatg cagcgctgat tgtatcaacc
     3961 atcgtcatgg tatttattaa atacttcctt cctccaacag ctgttagcta ctgggcatat
     4021 tcattgattt caatctctgt atcagtagtt tcaggttata ttgtatctgt tcttactgga
     4081 aataaagtat ctgcacctaa atatacaacg attcatgata ttacagaaat taaagcggat
     4141 tcaagttggg aagttcgtca ctaatagaaa agagaaaata atatgattat ttctgaacaa
     4201 tctgatttta aacgatatgc ttctgtcaat aaatattttt caaaagtctg tgatttttta
     4261 gaaaatacaa atttgacaga tttagttgat ggaaaaattg atattgacgg ggaaaatgtt
     4321 tttgcaaatt gtatga
//
LOCUS       DAVMCN010000092         4264 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVMCN010000092 DAVMCN010000000
VERSION     DAVMCN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.093"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(183..794)
                     /gene="rpsD"
                     /locus_tag="VYP85_001969"
     CDS             complement(183..794)
                     /gene="rpsD"
                     /locus_tag="VYP85_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1882422.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(989..2041)
                     /locus_tag="VYP85_001970"
     CDS             complement(989..2041)
                     /locus_tag="VYP85_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1882423.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2038..2736)
                     /locus_tag="VYP85_001971"
     CDS             complement(2038..2736)
                     /locus_tag="VYP85_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1882424.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2903..>4264)
                     /gene="pavB"
                     /locus_tag="VYP85_001972"
     CDS             complement(2903..>4264)
                     /gene="pavB"
                     /locus_tag="VYP85_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1882425.1"
                     /translation="DQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLI
                     SKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLK
                     ASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGT
                     QTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISKETVQKAVADNVKDSIDVPAA
                     YLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLG
                     ENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNI
                     VATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNT
                     MAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKK
                     EEN"
BASE COUNT         1122 a          947 c          858 g         1337 t
ORIGIN      
        1 aggattatac cacattgtgt actatttttg gttcatttta ctatatcact ttggactata
       61 tcggtctagt tatgtctcaa cgattatagc tggatactaa gagaaatcaa aaaagcacta
      121 agggagaacg tcccaaagtg cttaatatca aggcctcaaa gcctatctta ttcaataaaa
      181 tattacaaca ttttgttgta gaattcaacg acaagtgctt cgttgatttc tgggttgatt
      241 tcgtcgcgtt ctggcaagcg agtcaatgaa ccttccaact tttcagcgtc gaatgatacg
      301 aatgctggac gtccaagagt agcttctact gcttcaagga ttgctggaac tttcaatgat
      361 ttttcacgaa ctgagatcac ttgacctgga gttacgcggt atgatgggat atcaacgcgt
      421 ttcccgtcaa caaggatgtg accgtggttt acgaattgac gagcttgacg acgagtagtc
      481 gcgagaccaa gacggtaaac aacgttatcc aaacgacgtt ccaaaagaag cataaagttg
      541 aaacctagga ttccgccttt gatttttgta gcttgtacga acaagttacg gaattgtttt
      601 tcacctacac cgtaagtgaa acgaagtttt tgtttttcag ccaattgcaa accgtattct
      661 gacaatttag aacggttgtt tggtccgtgt tgtcctggta cgtagttacg acgtgccaat
      721 tctttacctg tacctgtaag tgaaaggcca aggcgacgag cttgtttcca agatggtcct
      781 gtataacgtg acatatgaat gtcctcctga tataaataat atttcggtgg aaatagtcac
      841 ttagaaagcc ctgattcgtg cagatgccct tcgcctaaac agccaaggtt acttgtcata
      901 agacacctgt tgacgagctt catgctttcc tgctgatatt tcacacaaaa tccattttac
      961 catgaatagc tggatttgta aaggggtttt aggctttatt ttcactacca gagaggttga
     1021 gaacaagggt aaaggtactt cctagaccgt actggctgct gactgtgatt tccccaccca
     1081 attgatgggc caattcacgc gcaatcgcaa gtcctaatcc atgaccacct gtcttcatgt
     1141 tacgcgaagt ttcgacacga taaaggcgtt tgaaaatatt ttccaaatcc tctggggcaa
     1201 tgccctgccc ttcatcggtc acactgattg aaagctggtc cttctccagc ttagccacca
     1261 cttccagctt ggttcctgga gcagaatatt taaaagcgtt atcgaccaga ttcaccaaga
     1321 tacgagaaag cttagcataa tctccctcaa tccgggcaga ctctgggatt acctgcaagt
     1381 ggacatctct tctctcctgc tcaatcaaaa actgaaattc actcatgcac tcaattaaga
     1441 gcttgtccag aaaaatactg tctttactgg tagtttccac ctgatttcta gctgtgttta
     1501 gggtcaaaaa attcaactcc tcaaccagtt tattgagcct ctccgtctgg cgtccaatgg
     1561 ttgctagata atgagcttgc tccgactcct tgataatccc atccaaaatc ccttctaccg
     1621 tcgcttggat cgaagtgata ggggtcttaa tatcatgcga caactgggca atcatcaagc
     1681 ccttttctcg ttcgctttct tccaaggaat caaagcttac ctgcaaatca tgggacatct
     1741 cattaaaagt ttgccctaat tgctgaaatt ctacaggacc ttgaacctcc aaatttgaag
     1801 gaaaatcctt ggccgctacc cgcttggcat gctccttgag tttgcccaac gacgtaaaga
     1861 ctggcaatag gagaaagaga ctaatcccag caccgacaag gctggcaacg atggtcatcc
     1921 caagcaaaaa gtaaatctcg cctttcgcaa tcagcatttt ttgaacagcc caaaaaacaa
     1981 ccaaaatggt taagagggtt gaaataatat atccaaccaa aatataactt tttagtttca
     2041 tgtttgtcct ctcggtttct ctatcttata tcccaacccc caaactgtct taatagtggg
     2101 cgtttggtca ctactatatt ttgccagctc ctgtcgaaga gcatggatat gcacattcaa
     2161 ggtattggtg tcatccacgt agtcttcttt ccagatcttt tcatagaggt ctgtcttgga
     2221 gaaaactcgc tctggattgc tagctaaaat ccacagcaat tcaaatgatt taacagttaa
     2281 atccagcatt tcttctccta tttgaacttc atgactacta tgattcattt ttagattgcc
     2341 aagggaaatc agctctgttt cgcccccacg atgaaggcgg cgcaaaatat tgtggacacg
     2401 caaaaccagc tcacgtgggc taaaaggctt agcaataaaa tcatctgctc ccaagctcag
     2461 gccgtaaatc ttgtcctgtt cactggtctt agcagtaata aataggaaag gctgctctgg
     2521 tgataagtat tgaacctcac tgattaaatc ataaccatcc atccgaggca tcatgacatc
     2581 tgtgataatc aaatcaatcg gttttttctt gaacagctct agcgcttcca gtccatcatg
     2641 ggctaccaag acctgataac ctgcctgaat taagtatctc tgatgaatat ctgtgatttc
     2701 tacctcgtcg tcaacgagta aaattgtctt tcccatctgt ctctcctttg ataaaaacag
     2761 tgctatactg ctttaagtat aacactattt ttattgtttt acgatgattt taatctgcta
     2821 ttgaaagaaa gtcctgattg ctgattgagt tgttaaacta atcttagtca gcccactatc
     2881 catcatttat ttccttagct gattagtttt cttctttttt gtttttcaaa cctagaccac
     2941 cgagtaaacc tgcaagcgca agcccaagga aaccaatact tgccattgat gtttgagtct
     3001 caccagtatt tggtagcata gctttatcct ctgacatcat cgtatcagac atcttgttag
     3061 cagaagcagc catgttttca cctgccatcg tgttggtaga acttgtcatg gtgtcagcag
     3121 gcatgctatc tgtagtacct gtagcatgat tgtgattcat cggagtcacg ccagaaccag
     3181 agttagaagg tgataatgaa ccatttgctg tgtctgatgt ttctttaaca tttatcttaa
     3241 tagtgacttt tttagttgct acgatgttgt ccaaatctgg tttaccgtct ttgttaccat
     3301 agacattgac tgtagcgctg taagtttgag taccatttgc tcggaactgg tcaatgagcg
     3361 cttgtttttc tttgccagct acatttccgt ccaaggctaa ttgatagaag tattgacctt
     3421 tggtcttcac gttttcacct agtggagata gagctgggtt tttagcgtcg ccgttatctg
     3481 accatggtgc cttgtcagat gccttgagca agagacgagt caacatacca tcacctgcga
     3541 agagttcgta tggaatcaca tggttgacac ctgctgtgaa tggaccttca cccttggcct
     3601 tttctaggta ggctgctgga acatcgatac tgtccttaac gttgtctgca acggcttttt
     3661 gaactgtttc tttagaaatt aaaccgttta tgttaatagt gactttttta gttgctacga
     3721 tgttgtccaa gtccggttta ccgtctttgt taccatagac attgactgta gcgctgtaag
     3781 tttgagtacc gtttgctcgg aactggtcaa tgagcgcttg tttttctttg ccagctacat
     3841 ttccgtccaa ggctacttga tagaagtatt gacctttggt cttcacgttt tcacctagtg
     3901 gagatagggc tgggttttta gcgtcgccgt tatctgacca tggtgccttg tcagatgcct
     3961 tgagcaagag acgagtcaac atgccatcac ctgcgaagag ttcgtatgga atcacatggt
     4021 tgacacctgc tgtgaatgga ccttcaccct tggctttttc taggtaggct gctggaacat
     4081 cgatactgtc tttaacgttg tctgcaacgg ctttttgaac tgtttcttta gaaattaaac
     4141 cgtttatgtt aatagtgact tttttagttg ctacgatgtt gtccaagtcc ggtttaccat
     4201 ctttgttacc atagacattg actgtagcgc tgtaagtttg agtaccattt gctcggaact
     4261 ggtc
//
LOCUS       DAVMCN010000093         4070 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVMCN010000093 DAVMCN010000000
VERSION     DAVMCN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.094"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            699..1691
                     /locus_tag="VYP85_001973"
     CDS             699..1691
                     /locus_tag="VYP85_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1882426.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQILSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1693..2511
                     /locus_tag="VYP85_001974"
     CDS             1693..2511
                     /locus_tag="VYP85_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1882427.1"
                     /translation="MIKLWIRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKQVQSFITIQGG"
     gene            2513..3298
                     /locus_tag="VYP85_001975"
     CDS             2513..3298
                     /locus_tag="VYP85_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1882428.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3337..3603
                     /locus_tag="VYP85_001976"
     CDS             3337..3603
                     /locus_tag="VYP85_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1882429.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGAN"
     gene            3552..3797
                     /locus_tag="VYP85_001977"
     CDS             3552..3797
                     /locus_tag="VYP85_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1882430.1"
                     /translation="MSRRKKAYQGRKIGSQLIATLESEARKKVAYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1135 a          686 c          882 g         1367 t
ORIGIN      
        1 tcttcatcag aatgataaaa ttaatcaatt gatatctgat tacaaacaga atatgaaagc
       61 tttttatatc actattgaaa aatttatacg agatgatgaa agccttaagt gttattttat
      121 aaaggttatt tcaagtcgtt ccaaggtaac aagtctagat cagattgaag ctgataaaac
      181 gatacaaaga aaatattcaa gtgagctaaa aaaatttatt ggattttata atgagattat
      241 ttgtgaggaa aatagtttcc tacatgtacg aaagaggtgg tcgagttggt ttaggtagtc
      301 gatgcgtgag ttgataattc tcagggtatg gacttctttt tcatgaatga ggtaaaagag
      361 caggtattgt ttagagacaa tcattctgag catattttct ggatagaggg agtatccgat
      421 tttatgatca aagttaatac cgccctctgg tgagaagatg agtaggttgg taatttaaac
      481 tattaaacag aatttttgat taaaagtatt attttatgag agaaatccta atttcacaat
      541 ccataggcaa tcgcttgcat tctgtttttt attggactat aataggttgg tataaagcct
      601 tctgtagtaa taaaatgtag aaggtgtaga aagtaaggat ttagaatatt tgtagttaaa
      661 aacacaatgt tgctattcct tacgataggg agatagatat ggcaatgata gaagtggaac
      721 atcttcagaa aaattttgtg aagactgtta aggaaccggg cttgaagggg gctttgcgct
      781 cctttattca tcctgaaaag cagacctttg aagcggtcaa ggatttgacc tttgaggttc
      841 caaaagggca gattttagga tttatcgggg caaatggtgc tgggaagtcg acaaccatta
      901 aaatgctgac aggaattttg aaaccaacat ctggtttttg tcggattaac ggcaagattc
      961 cccaggataa tcggcaagat tatgtcaaag atattggcgt agtctttgga caacgcaccc
     1021 agctatggtg ggatttggct ctgcaagaga cctacactgt cttaaaagag atttatgatg
     1081 tgccagactc gctctttcat aagcgtatgg actttttgaa tgaagtcttg gatttgaagg
     1141 actttatcaa ggatcccgtg cggactcttt cactgggaca acggatgcgg gcggatattg
     1201 cggcctcctt gctccacaat cccaaggttc tttttttaga tgagccgacc attggtttgg
     1261 acgtttcggt taaggataat attcgtcggg caattactca gatcaatcaa gaggaagaaa
     1321 ctaccattct tttgaccact cacgatttga gtgatattga gcaactttgt gatcggattt
     1381 tcatgattga caaggggcaa gagatttttg atggaacggt gagccaactc aaggagacct
     1441 ttggtaagat gaagactctc tcttttgaac tgctaccagg tcaaagtcat ctggtctctc
     1501 actatgaagg tctgtctgat atgaccattg atagacaagg aaacagcctc aacattgaat
     1561 ttgatagttc tcgctatcag tcagctgaca ttatcaagca aatcctgtct gattttgaaa
     1621 tccgcgattt gaagatggtg gatacggata ttgaggatat tatccgtcgc ttctaccgaa
     1681 aggagctcta ggatgatcaa attgtggata cgttataaac cctttatcaa tgcaggggtt
     1741 caggagttga ttacttaccg agtcaacttt attctctatc ggattggcga tgtcatgggg
     1801 gcttttgtgg ccttttatct ctggaaggct gtctttgatt cttcgcaaga gtctttgatt
     1861 cagggcttca gtatggcgga tatcaccctc tacatcatca tgagttttgt gaccaatctt
     1921 ctgactagat ccgattcgtc ctttatgatt ggggaggagg tcaaggatgg ctccattatc
     1981 atgcgtttgt tgcgaccagt gcattttgcg gcctcctatc ttttcaccga gcttggttcc
     2041 aagtggttga tttttatcag cgttggcctt ccatttttaa gtgtcattgt cttgatgaaa
     2101 atcatatcgg gtcaaggtat tgtagaggtg ctaggattaa ctgtccttta tctttttagc
     2161 ttaacgctcg cctatctgat taactttttc tttaatattt gctttggatt ttcagccttt
     2221 gtgtttaaaa atctttgggg ttccaaccta cttaagactt ccatagtggc ttttatgtcg
     2281 gggagtttga ttcccttggc attctttcca aaggttgttt cagatattct ctcctttttg
     2341 cctttttcat ccttgattta tactccagtt atgatcattg ttggaaaata cgatgccagt
     2401 cagattcttc aggcactcct tttgcagttc ttctggctct tagtgatggt gggattgtct
     2461 cagttgattt ggaaacaggt ccagtccttt atcaccattc aaggaggtta gtatgaaaaa
     2521 atatcaacga atgcatctga tttttatcag acaatacatc aaacaaatca tggaatataa
     2581 ggtggatttt gtggttggtg tcttgggagt ctttctggct caaggcttga atctcttgtt
     2641 tctcaatgtc atctttcaac atattccatt cctagaaggt tggacctttc aagagatagc
     2701 tttcatttat ggattttcct tgattcccaa gggaatggac catctctttt ttgacaatct
     2761 ctgggcacta gggcaacgcc tagtccgaaa aggagagttt gacaagtatc tgactcgtcc
     2821 catcaatcct ctctttcaca tcctagttga aacctttcag attgatgcct tgggtgaact
     2881 cttagtcggt ggtattttat tgggaacaac agtgaccagc attgtttgga ctcttccgaa
     2941 attcctgctt ttcctagttt gtattccttt tgcgaccttg atttatactt ctcttaaaat
     3001 cgcaacagcc agtatcgcct tttggactaa gcagtcaggc gccatgattt acatcttcta
     3061 tatgttcaat gactttgcta agtatccgat ttctatttac aattctcttc ttcgttggtt
     3121 gattagcttt atcgtgcctt tcgcctttac agcctactat ccagctagtt atttcttaca
     3181 ggaaaaggat gtgttcttta acgtaggagg tttgatgttg atttctctgg ttttctttgt
     3241 tatttccctt aaactttggg ataagggctt agattcctac gaaagtgcgg gttcgtaaaa
     3301 gctaaagtaa gactaaaatc aagaaagaaa cttatgatgt ttgtaattga agaagtcaag
     3361 gatgaaaatc aaaaaaaggc agttgtagct gaggttttga aggatttgcc agaatggttt
     3421 ggaatcccag aaagcacaca agcctatata gaaggaacca cgacactgca agtttggacc
     3481 gcctatcagg agagtgattt gactagattt gtaagcttat cctattcgag tgaagattgt
     3541 gcagagattg attgtctcgg cgtaaaaaag cttatcaagg tagaaaaatt gggagccaat
     3601 tgattgctac tttagagagt gaagctcgta aaaaagttgc ttatctgcag gtcaaaacag
     3661 tggcagaagg ttctaataaa gattatgatc gaacaaatga cttttatcga ggtcttggct
     3721 ttaaaaagtt agagattttt cttcaactat ggaatccgca aaatccttgt cagattttga
     3781 ttaaaaagct tgaataatat tacttgacat ctattctcag agtgctatac tgtaagtgta
     3841 atcgccgatt tagcttagtt ggtagagcaa ggcactcgta aagcctaggt tataggtaga
     3901 taaacgactg aggatttgaa aaaatagata ggtagaagat aaccgttaag ccttattctt
     3961 agcggttatt tatattgttt aatagcgctg atatttcatc aattatgcct gttttcgtgt
     4021 ttctggtagt tgttcaagtt tattgctact atttttgatg gtatgaatgt
//
LOCUS       DAVMCN010000094         4032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVMCN010000094 DAVMCN010000000
VERSION     DAVMCN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.095"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..588
                     /locus_tag="VYP85_001978"
     CDS             <1..588
                     /locus_tag="VYP85_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1882431.1"
                     /translation="LYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRN
                     KNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYK
                     PSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLTG
                     LKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
     gene            798..3917
                     /gene="phtE"
                     /locus_tag="VYP85_001979"
     CDS             798..3917
                     /gene="phtE"
                     /locus_tag="VYP85_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1882432.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1506 a          665 c          789 g         1072 t
ORIGIN      
        1 ctttatgagg cacctaaggg gtatagtctt gaggatcttt tggcgactgt caagtactat
       61 gtcgaacatc caaacgaacg tccgcattca gataatggtt ttggtaacgc tagcgaccat
      121 gttcaaagaa acaaaaatgg tcaagctgat accaatcaaa cggaaaaacc aaacgaggag
      181 aaacctcaga cagaaaaacc tgaggaagat aaggaacatg atgaagtaag tgagccaact
      241 caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc agataatctt
      301 tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac tacagatgag
      361 gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga ggcggaggcc
      421 ttgctagaaa aagtaacaga ttctagtatt agacaaaatg ctgtggagac attgactggt
      481 ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc agaagtagat
      541 agtctcttgg ctttgttaaa agaaagtcaa ccgactccta tacagtagta aaatgaatgg
      601 agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa aaacgtaaca
      661 gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta aatggttaaa
      721 taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac ttcatcattt
      781 attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga tcagctgtta
      841 tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag gaaaataagg
      901 acaataatcg tgtctcttat gtagatggca gccagtcaag tcagaaaagt gaaaacttga
      961 caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta atcaaaatta
     1021 cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat gggaaagttc
     1081 cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat caacttaaag
     1141 acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat ggaaaatatt
     1201 atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat gaaatcaatc
     1261 gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt gctgtagcaa
     1321 ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct gatattatcg
     1381 aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac attcccaaaa
     1441 gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga aaaaatatgc
     1501 aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa tctgtagcaa
     1561 aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt ttgaaggaac
     1621 tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc tttgaccctg
     1681 ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac cattaccact
     1741 ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg gtgcctatca
     1801 gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg tctagtctag
     1861 gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct tcagcatctg
     1921 atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct tatattgtaa
     1981 gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa ccgactcttc
     2041 caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga atttcacatg
     2101 agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct gaagatgaat
     2161 caggatttat catgagtcac ggtaatcata atcattactt cttcaagaag gacttgacag
     2221 aagagcaaat taaagctgcg caaaaacatt tagaggaagt taaaactagt cataatggat
     2281 tagattcttt gtcatctcat gaacaggatt atccaggtaa tgccaaagaa atgaaagatt
     2341 tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt gtcaaacgtg
     2401 aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga gatcaccatc
     2461 atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac agtaactatg
     2521 aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt tatactggag
     2581 aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat caaaacttta
     2641 ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg gagaaaaaat
     2701 taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg gagaaagtat
     2761 ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta gatcaacctt
     2821 atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca gaagtaagtt
     2881 atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt caaacgattt
     2941 tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt gcagtgccta
     3001 aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct tatttagaaa
     3061 ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa ggaacaacca
     3121 gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg gacaatcaat
     3181 cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat aaaccaagta
     3241 ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat gaaaaggtag
     3301 aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact gggaatagta
     3361 ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa aaagtagcaa
     3421 aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg gacggaacaa
     3481 ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat tttacaggag
     3541 aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta tctactggaa
     3601 cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag gcaccaaacg
     3661 aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca gaagggaatg
     3721 tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta gatcctgtac
     3781 aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt gttatattca
     3841 atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa aagaatttat
     3901 ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat gaagttctct
     3961 caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt aatatataaa
     4021 atttcttgac at
//
LOCUS       DAVMCN010000095         4023 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVMCN010000095 DAVMCN010000000
VERSION     DAVMCN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.096"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(94..1284)
                     /locus_tag="VYP85_001980"
     CDS             complement(94..1284)
                     /locus_tag="VYP85_001980"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1882433.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(1499..2842)
                     /locus_tag="VYP85_001981"
     CDS             complement(1499..2842)
                     /locus_tag="VYP85_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1882434.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(3222..>4023)
                     /locus_tag="VYP85_001982"
     CDS             complement(3222..>4023)
                     /locus_tag="VYP85_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1882435.1"
                     /translation="YTPQVTEETIKVGQTPDLTDNVTNLPNLPAGTKVVDITPAGQID
                     TTKPGTYTGKVRVDYPDGSSTEVSVSVNVLPAPETQTYKVTYRFESATADNNLPAEVL
                     SLLPQSGTYTTSSSVAIAFVPEAPMPVEVAVANGTWTFLGYQEVEEGSNLTFVGKWVF
                     EAKQDPSPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDNNQADRHQSEQPRKPEENPPA
                     QGPAGEKEKQATLPNAGSTAPLSLTGLVTSSLLAGLAVLLLGRKRKDD"
BASE COUNT         1142 a          895 c          760 g         1226 t
ORIGIN      
        1 gtaaatctct actttcgcaa aatggatttt cagaacagta tcccagtata gttaaaaact
       61 ataaaaaaga gaggacgttc ccctcttaaa atcttatttt actgcttctt tcaaagcatc
      121 taccttatct aaacgttccc atggaagatc aatatctgta cgtcccatgt gaccgtaagc
      181 cgatgtttga cggtaaattg gacgcttaag gtccagcatt tggataatcc ctgcagggcg
      241 aaggtcaaag atttgacgag ccgctttttc aagttgactt tcagctactg ttcctgtacc
      301 gaaagtatcg atacgaacag aaacaggttg cgcaacaccg atagcatagg ccaactgcac
      361 ttctgccttc ttagcaaggt ctgctgcaac gatattcttg gcaatatagc gagccgcata
      421 agaggctgaa cgatccacct tagtcgcatc tttaccagag aaggcaccac caccatgacg
      481 agagtagcca ccataagtat ctacaataat cttacgacca gtcaaacctg agtccccttg
      541 aggaccaccg attacaaaac gacctgtcgg attgataaag aattttgtct tatcatcaag
      601 ataagaagat ggaataactt ctttgatgac cttgtcaatc acatcttgat ggatttgttc
      661 attagtggcc tctggatcat gctgagtaga aataacgact gtatctacac gtaccggacg
      721 gtcattttca tcgtactcaa ctgtaacttg tgattttgca tctggacgga gatagctaat
      781 ttctccagac ttacgaagtt ctgccagacg acgaaccaat ttatgactga gtgcaattgg
      841 caatggcatg agctcttctg tttcatctac tgcaaatcca aacatgagcc cttggtcacc
      901 tgctccaatc aagtccagtg gatcttgatc agcatttcca cgaacctcca aggcttcgtt
      961 aacaccttga gcgatgtcag gagattgttc caccaaagat gggtgtactc ccaccgtctc
     1021 agcagaaaat ccatattctg tattggtata accaatctct gcaatggtat cacgaaccac
     1081 acggttaata tccacatagg catttgtaga aatttcacca aaaacgtgga cagaaccagt
     1141 atatacagct gtttcagcag caacgtgcgc ctctggatcc tttgctaaaa tagcatccaa
     1201 aatcgcatct gaaatttggt ctgcaatctt atccggatgc ccctcagata cagattcaga
     1261 cgtgaataat ttacgctctg acataaaaat gtcccccctt aaaaaatatt gttatagagt
     1321 tacaaagtac tgataggaaa actcttcgta ataaatacct accatcttat cgggactata
     1381 taactttatc attataccat ttttaatcgc aatttgcagt ctttaatgta gtgtttcggt
     1441 ttagatagtt cgttctcata aataaaaaag ttggagctca atactccaac aatttctatt
     1501 aaaatgtttg gcgtttagct ttacgctctg cacgaccgcg agcgcgattt tcagcacgct
     1561 tggttttacg gcgcttttca tcaaccgccc attgaatttt cttcttataa cccggtttga
     1621 cttttttctt tttcttttta accaaaccaa tcatttcgat atcaagttta tcttgttttt
     1681 tctcacggtt ggcacgacga tcacggtcat aggtatcttg aaattccccg tctttgacca
     1741 tcttaggact aaacttgatt cccaatttct ccaactcacg gatatccgag tcatcacttg
     1801 gctgataaag ggtaatagct gtacctggta ggccatttcg tccagtacga ccaacacgat
     1861 gaacaaaaaa agataagtct tgcggaatgg catcattgat gacatggctg acaccttcaa
     1921 tgtcaatccc acgcgctgct aaatctgttg cgacaatata ctcaaaatcc agattttgca
     1981 cctgattcat gattcgcttg cgttcacgag gggcaatatc tccatggatt tttgcaacct
     2041 tcaagccttg agcagtcaga tatgaatgca attcatcagc acgcgtttta gtgttaacaa
     2101 aaatcattgc caaatacggc tgcatcaact gagtcaactg gtaaatttga gcattcttat
     2161 catgtccctt ggtcgaaatc aaccaattat caatggtgtc agaaataacc gttttggtct
     2221 taattttctc cataacagga ttggataagt attttttcaa gaatggttgc agtttttgtg
     2281 ggatagtcgc tgagaagacc atgaattgca agtcttttgg aagactgcca gcaatcttat
     2341 caacagtttc caagaatccc atatccaagg tcatatctgc ttcatcaaca acaaatgtct
     2401 tggctttatg aatagctaaa tcaccagatt taaccaagtc gtagatacgg cctggtgttc
     2461 caataacaat atgaggctga ttgcttgcca atttctcaat ctggcgagcc ttatccgtac
     2521 cacccacata attaaccaca cgaacttcga catctgagtg agctgaaatc tgacgcgcta
     2581 cttggtaaat ttgagtagcc aactcacgac tcggtgcagt aatcactgct tgtacactat
     2641 cgctagcttc atctaattgc tggaaaatcg gtaacaagaa agtatgagtc ttacctgaac
     2701 ctgtttttga ttctcctact aggtcacgac ctgccaaaac aataggaatc aacttgtctt
     2761 gcacctctgt tggagttgta aattttaact ccttcaaggc ttctctaata tagtttttaa
     2821 attgaaattt cgtaaatgac ataacatcct cgattctatc tatcttatca attataccat
     2881 attttgaaca ttttcagtag tccgactcat ctgacctatc acaaggctct caatttctct
     2941 aaatatagta aaatgaaata agaataggat gaatcgatca ggacagtcaa atcgatttct
     3001 aacaatgttt tagaagcaga ggtgtactat tctagtttca atctactata cctctcttat
     3061 actaaaaatc atacatttgc tttctttcca aaatgcaaaa agagaagacc aaattggtct
     3121 tctctcagcc ttaaagcttg cgactcagat agatttgtca aacagtcaaa cagttgctta
     3181 agaatcttgt aaaagtcgaa agcttctaga aaaattagta cttaatcatc tttccgcttg
     3241 cgaccaagaa gcaacactgc tagacctgca agaagagagc tagtcactag tccagtgagt
     3301 gaaagtggtg cagtactacc cgcatttggc aatgtagctt gtttttcctt ttctcctgct
     3361 ggaccttgag ctggtggatt ctcttcaggt tttcttggtt gttctgattg atgtctatct
     3421 gcctgattat tatcagttcc ctgctctccc cctggattca ctggtggaac tggatttggt
     3481 tgaggtgctg gttgtggcgt tggtgccggc tgtggttgtg gactaggatc ttgcttagct
     3541 tcaaagaccc acttaccgac gaaggttaga tttgacccct cttccacttc ttggtaacct
     3601 aagaatgtcc atgtaccatt tgcaacagca acttctacag gcatcggtgc ttctggaacg
     3661 aaagcaatcg ctacagaaga acttgtagta tatgttccac tttgtgggag taagctcaat
     3721 acttctgctg gcaagttgtt gtctgcggtt gcactttcga agcggtaagt caccttatag
     3781 gtttgagttt ctggtgcagg caaaacatta actgatacag acacctcagt agaagaacca
     3841 tctggatagt caactcgcac cttacctgtg taagtacctg gttttgttgt gtcaatttga
     3901 cctgcaggtg taatatcaac taccttagtg ccagctggaa ggtttggcaa gttcgtcaca
     3961 ttatcggtca agtcaggtgt ttgtccaacc ttgatagttt cttccgttac ctgaggcgta
     4021 taa
//
LOCUS       DAVMCN010000096         3960 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVMCN010000096 DAVMCN010000000
VERSION     DAVMCN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.097"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            371..598
                     /locus_tag="VYP85_001983"
     CDS             371..598
                     /locus_tag="VYP85_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882436.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKN"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VYP85_001984"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VYP85_001984"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1882437.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKETLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1357 a          651 c          872 g         1080 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata agaattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgctaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgac gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaaga aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aagaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga gggagaaaag gaagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaaaatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacacttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacaag aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtatagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
//
LOCUS       DAVMCN010000097         3839 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVMCN010000097 DAVMCN010000000
VERSION     DAVMCN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.098"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(17..1432)
                     /locus_tag="VYP85_001985"
     CDS             complement(17..1432)
                     /locus_tag="VYP85_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1882438.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1445..3283)
                     /locus_tag="VYP85_001986"
     CDS             complement(1445..3283)
                     /locus_tag="VYP85_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1882439.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIVLVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     FSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3301..>3839)
                     /locus_tag="VYP85_001987"
     CDS             complement(3301..>3839)
                     /locus_tag="VYP85_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1882440.1"
                     /translation="SSSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELG
                     IELPIDEAAFIALHFVNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYR
                     FITHIKLFAHRLVENTTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTS
                     SELVYLMAHIRRLTKNLD"
BASE COUNT         1290 a          764 c          507 g         1278 t
ORIGIN      
        1 atcatcaata aacaaactat ttgaataagg attctccatt tgattcaatc actcctttat
       61 accaagtaaa ggacattttc ttatatcgat tgaatgtgcc atttccatca tcatttcgat
      121 caacataaat gagaccgtac cttttagaaa gttgtgcagt ggacatagaa acacagtcaa
      181 tacatcccca agacgtatag cccataattt caacaccatc ctgtagagct tcagcaactt
      241 gcaataaatg ttctttcata tactgaattc tataatcatc ttggactgtt aagttattaa
      301 attcatcttt tattagttga tctttagcac ctaatccgtt ttccactata aataatggaa
      361 tttgataacg gtcataatat ctatttaaaa ttatacgtag tccaattgga tcaatttgcc
      421 atccccactc agaagactct aaataaggat ttactaagcc accaataata ttcccttctc
      481 ctgaattata ctgtgttgga agagcagatt gagtcacact catgtaatag ctaaaggata
      541 aaaaatctac ggtataattt tttaataact ctgcatcttc agctgcaaac tctatgttaa
      601 tgtcatgttc cttaaaatat ctttttgcat aattcggata ataacctcta acatgcacat
      661 ctgaaaatag ataatttaga ttctcatact catgagtcgc ccatacatct tttggatttg
      721 gagtcattgg ataagctggc atagctaata ccatacatcc taccttaaac tctgaattaa
      781 tctcacgagc aatttttgta accaaacttg aggcgactaa ttcatgatgt atagcttgat
      841 ataattcttg tttcgaaaga ttctccttag gtatatctat tcctccacta gtaaatggta
      901 attccaaaac agagtttact tcgttaaatg taagccaata tttaacttta tctttatacc
      961 tttctaaaac tgttcgagca aatttttcat aaaaatgaat cattctccta tcaacccatc
     1021 catgatattt tcttgctaaa tataatggag tctcatagtg tgaaagagtt acaagtggct
     1081 ctatcccgtg agcatgtagt tcatcaaaca attcatcata atatttcaaa ccagcttcgt
     1141 taggttcttc ttcatctcct tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa
     1201 cattaaagcc catttcagaa aacaaggata tatcttcctt atatttatga taaaaatcaa
     1261 tacctaacaa ttttaagtta tcttctgtag gattttctgt tgcttctcct aatccacctt
     1321 tgggtaacac atcctgaact gataagccct taccatcttc attatatgct ccctctactt
     1381 gattagctgc aacagctcca ccccaaagaa aatcatctgg aaaaatggtc ataactttcc
     1441 tccattataa tattaccagt aattccttag aatgctcgat tgtctgatta ttaggtaata
     1501 ctaatacatc tagaaaatca ttggtattcg ttacaattac tggtgtaact gtttcgtagc
     1561 ctttagtctt gattaaattc aagtccattt caaaaatcaa ctgatttttg aaaactctgt
     1621 ctccttcttc tacatgacta ataaaacctt gaccttttag ctcaacagta tctaatccaa
     1681 tatgaattag taactcaaca ccctcatcac tcttcaatcc aattgcgtgc ttagtcggaa
     1741 aaatatttgt aattttccca tcaaatggtg cataaacctt accttcactt gggataattg
     1801 ctactccgtc tccaattagt ttatctgaaa atgttttatc ctggacatcg cttaacggaa
     1861 tgatttctcc tgatatagga gaaaatatca tttttttatt tgaaactcca acttcaactt
     1921 ctaaattgct aaaactctct tcttcatcga ttccaaatat ataagctaat acaaaggtaa
     1981 taacaaccga aatgaccgcc acaattaaag catttacaat atttgatggc acatcagaat
     2041 aaataaattg aggcaacgct atcaaagatg ggacagcaaa tagatatgct ttaacactag
     2101 taagacctgc aaataatccc gctaatccac caccaatcat agctgcataa agcggttttt
     2161 tatattttaa agtcacacca tataatgcag gttcggtaat ccctgcaagt aaggctgaga
     2221 aacctgctgc aaaagcaatt tgttttgtat tattattttt actctttaat gcaacagcca
     2281 tcgaagcagc cccttgagct aagtttgacc ctaacattgc tggaagaatt aatacgtctg
     2341 gagtagcaat agatgccgcc aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa
     2401 caataaatgg cataatagca ccaagaatag ctaatgtaag ccatccagct acaccataca
     2461 tttgcccaac tagatttgat aatccttcac caacaattac tccaataggt ccgactacaa
     2521 ctaagacaat acagcttgat actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa
     2581 tagctggtgt taatttagca attatttttt caatatattt catcaaccaa accataataa
     2641 gaattggaac gactgacgaa ccataactag ctggtgtcac aggtacacca aataaactaa
     2701 gaggattccc tgattgcacc atttgaacaa aatttggatg gagaagtaca cctgctacag
     2761 acatagctaa tgtagatgtt acttttaatt tttgtgatgc agaataagct aataacagcg
     2821 gtaagaaata atatggagca tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg
     2881 attgcaatat accaagcatt ggtaaaataa ttaccaagac tttcagcata cctcccccta
     2941 acattgctgg aatgattgga gtcatggaac cagcgatata ctcaatgatt ctttctaaaa
     3001 tattcccttt gtgcccttga acaactgaat cggattcaaa attgccaagt ttaacgaatt
     3061 ctttataata attagctaca tcattaccaa gtataatttg atattgtcca ttctttttca
     3121 taatacctat tacacctggt atcttcttca catcatcatc attgactaaa ttttcatctt
     3181 ttaattctaa tcttaaacgt gttacacaat gggtaactct attgacattt ttttcacctc
     3241 caattacatc gaggattttt tgtaccttat ctttataact catggtattc tcctattcta
     3301 ttaatctaaa ttttttgtta agcgacgaat atgagccatc aaataaacta attcactaga
     3361 agtcagcaaa taattgtact cagtttgtat aaacattgcc acctgttcac cacattcata
     3421 ttctctagga tatttatttt tcattaatgc taacaagtct tcatcatcat cgtcacaata
     3481 agttgtattt tcaaccaagc gatgggcaaa taattttata tgagttatga atctataata
     3541 atcaatagaa tcttggttaa actcagtaca atagaaatct tgaatgattt tctcaattcc
     3601 cataattatt tcagtgattt tatacgactc ttgaaaatta ttttctaaat tagcattaac
     3661 aaaatgtagc gctatgaatg cagcttcgtc aattggaagt tcaataccta actctttttt
     3721 tattatttgt aaagcccttt tcccaagttc aaattcttct ttataatatt tcgatatttc
     3781 ccagcgtagg ggattcgaaa taataactcc ttctttataa cgttctatac tcgaagaaa
//
LOCUS       DAVMCN010000098         3743 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVMCN010000098 DAVMCN010000000
VERSION     DAVMCN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.099"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            74..1255
                     /locus_tag="VYP85_001988"
     CDS             74..1255
                     /locus_tag="VYP85_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1882441.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            1313..2071
                     /locus_tag="VYP85_001989"
     CDS             1313..2071
                     /locus_tag="VYP85_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1882442.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            2284..3645
                     /gene="dnaA"
                     /locus_tag="VYP85_001990"
     CDS             2284..3645
                     /gene="dnaA"
                     /locus_tag="VYP85_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1882443.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
BASE COUNT         1330 a          646 c          670 g         1097 t
ORIGIN      
        1 aaacttttgt gtttaagtta taattaagct agtcagttta tactttcagt aattcaaaca
       61 tatggaggca aatatgaaac atctaaaaac attttacaaa aaatggtttc aattattagt
      121 cgttatcgtc attagctttt ttagtggagc cttgggtagt ttttcaataa ctcaactaac
      181 tcaaaaaagt agtgtaaaca actctaacaa caatagtact attacacaaa ctgcctataa
      241 gaacgaaaat tcaacaacac aggctgttaa caaagtaaaa gatgctgttg tttctgttat
      301 tacttattcg gcaaacagac aaaatagcgt atttggcaat gatgatactg acacagattc
      361 tcagcgaatc tctagtgaag gatctggagt tatttataaa aagaatgata aagaagctta
      421 catcgtcacc aacaatcacg ttataaatgg cgccagcaaa gtagatatta gattgtcaga
      481 tgggactaaa gtacctggag aaattgtcgg agctgacact ttctctgata ttgctgtcgt
      541 caaaatctct tcagaaaaag tgacaacagt agctgagttt ggtgattcta gtaagttaac
      601 tgtaggagaa actgctattg ccatcggtag cccgttaggt tctgaatatg caaatactgt
      661 cactcaaggt atcgtatcca gtctcaatag aaatgtatcc ttaagatcgg aagatggaca
      721 agctatttct acaaaagcca tccaaactga tactgctatt aacccaggta actctggcgg
      781 cccactgatc aatattcaag ggcaggttat cggaattacc tcaagtaaaa ttgctacaaa
      841 tggaggaaca tctgtagaag gtcttggttt cgcaattcct gcaaatgatg ctatcaatat
      901 tattgaacag ttagaaaaaa acggaaaagt gacgcgtcca gctttgggaa tccagatggt
      961 taatttatct aatgtgagta caagcgacat cagaagactc aatattccaa gtaatgttac
     1021 atctggtgta gttgttcgtt cggtacaaag taatatgcct gccaatggtc accttgaaaa
     1081 atacgatgta attacaaaag tagatgacaa agagattgct tcatcaacag acttacaaag
     1141 tgctctttac aaccattcta tcggagacac cattaagata acctactatc gtaacgggaa
     1201 agaagaaact acctctatca aacttaacaa gagttcaggt gatttagaat cttgattgac
     1261 atctatgtaa agaaagcttt acataagaga aaagatgtgt tagtgtagaa tcatggaaaa
     1321 atttgaaatg atttctatca cagatataca aaaaaatccc tatcaacccc gaaaagaatt
     1381 tgatagagaa aaactagatg aactagcaca gtctatcaaa gaaaatgggg tcattcaacc
     1441 gattattgtt cgtcaatctc ctgttattgg ttatgaaatc cttgcaggag agagacgcta
     1501 tcgggcttca cttttagctg gtctacggtc tatcccagct gttgttaaac agatttcaga
     1561 ccaagagatg atggtccagt ccattattga aaatttacag agagaaaatt taaacccaat
     1621 agaagaagca cgcgcctatg aatctctcgt agagaaagga ttcacccatg ctgaaattgc
     1681 agataagatg ggcaagtctc gtccatatat cagcaactcc attcgtttac tttccttgcc
     1741 agaacagatt ctttcagaag tagaaaatgg caaactatca caagcccatg cgcgttccct
     1801 agttgggtta aataaggaac aacaagacta tttctttcaa cggattatag aagaagatat
     1861 ttctgtaagg aaattagaag ctcttctgac agagaaaaaa caaaagaaac agcaaaaaac
     1921 taatcatttc atacaaaatg aagaaaaaca gttaagaaaa ctactcggat tagatgtaga
     1981 aattaaacta tctaaaaaag acagtggaaa aatcattatt tctttttcaa atcaagaaga
     2041 atatagtaga attatcaaca gcctgaaata aggctgttct tttatttttt tatctcacaa
     2101 ggttatccac tatgtttttc gataaaaagc ttaataaatc aataatttct tcttttatcc
     2161 ccaacctgtg gataaagttt ggtaacattg tggattattt ttcacagctt gtggaaaatt
     2221 cttgctatct atggtaaaat atctctagta ttaaactttt aaatagtaaa ggaggagaaa
     2281 ggattgaaag aaaaacaatt ttggaatcgt atattagaat ttgcacaaga aagactgact
     2341 cgatccatgt atgatttcta tgctattcaa gctgaactca tcaaggtaga ggaaaatgtt
     2401 gccactatat ttctacctcg ctctgaaatg gaaatggtct gggaaaaaca actaaaagat
     2461 attattgtag tagctggttt tgaaatttat gacgctgaaa taactcccca ctatattttc
     2521 accaaacctc aagatacgac tagctcacaa gttgaagaag ctacaaattt aactctttat
     2581 aactatagtc caaagttagt atctattcct tattcagata cgggattaaa agaaaagtat
     2641 acctttgata actttattca aggggatgga aatgtttggg ctgtatcagc cgctttagct
     2701 gtctctgaag atttggctct gacctataac cctcttttta tctatggagg accaggcctt
     2761 ggtaagactc acttattaaa cgctattgga aatgaaattc taaaaaatat tcctaatgcg
     2821 cgtgttaaat atatccctgc cgaaagcttt attaatgact ttcttgatca cctaagactt
     2881 ggggaaatgg aaaagtttaa aaagacctat cgtagtcttg atcttttgtt aatcgatgat
     2941 attcagtcac tcagcggaaa aaaagttgca actcaggaag aatttttcaa tacctttaac
     3001 gcccttcatg acaagcaaaa acagattgtc ctaacgagtg atcgtagtcc aaaacatcta
     3061 gaagggctcg aggagaggct tgtcacgcgt tttagttggg gattgacaca aactatcaca
     3121 ccccctgact ttgaaacacg tattgccatt ttacaaagta aaacggaaca tttaggctac
     3181 aatttccaaa gtgatactct agaataccta gctgggcaat ttgattcaaa tgttcgagat
     3241 cttgagggag ccatcaacga catcacttta attgccagag taaaaaaaat caaggatatc
     3301 actattgata ttgctgcaga agccattaga gcccgcaaac aagatgttag ccaaatgctc
     3361 gtcatcccaa ttgataaaat ccaaactgaa gttggtaact tttatggtgt tagtatcaaa
     3421 gaaatgaagg gaagtagacg ccttcaaaat attgttttgg cccgtcaagt agccatgtat
     3481 ttatctagag aactaacaga taatagtctt ccaaaaattg ggaaggaatt tgggggaaaa
     3541 gatcatacca cagtcattca tgcccatgcc aaaataaaat ctttgattga tcaagacgat
     3601 aatttacgtt tagaaattga atcaatcaaa aagaaaatca aataatttgt ggataacttt
     3661 tagtttttta tcttttttat ccacattttt taaacaagct aaaaaacttg atatgacttg
     3721 tttaaaggct gttttccaca gat
//
LOCUS       DAVMCN010000099         3734 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVMCN010000099 DAVMCN010000000
VERSION     DAVMCN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.100"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            68..544
                     /locus_tag="VYP85_001991"
     CDS             68..544
                     /locus_tag="VYP85_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882444.1"
                     /translation="MSRTYINIRLAYETKYWLECIQEEVQKKLDALINEQDIEELESI
                     ITNKLEKKDSLLGAVSITTFFKVSSSSVIEKAYNETKNYTTSEWREIARQMNLAKVKQ
                     NMEIGTLTPRLYLDNNIISELEKYQFLFKSDDMIRQVRMSYVIKMVAFAYYKKLFA"
     gene            715..1269
                     /locus_tag="VYP85_001992"
     CDS             715..1269
                     /locus_tag="VYP85_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882445.1"
                     /translation="MPKLLETEKYSLDSIIDGGKLRMISKFCPDLHGLRYEFKTSDSI
                     TKEYCKKIRQALRDSDPEGKSGKKCMMRYTIDILNVWNTLCRTRDFITGSLKADDVID
                     GKTGIYFFDVNTSNVITDDVIENVKINHKSLVRNVDEENIESISKEIPKGTDMYYYVL
                     YRLGLNRIKYNYLVKALAGAIQKD"
     gene            1545..1931
                     /locus_tag="VYP85_001993"
                     /pseudo
     CDS             1545..1931
                     /locus_tag="VYP85_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
     gene            1925..2047
                     /locus_tag="VYP85_001994"
                     /pseudo
     CDS             1925..2047
                     /locus_tag="VYP85_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            2051..3184
                     /locus_tag="VYP85_001995"
     CDS             2051..3184
                     /locus_tag="VYP85_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1882446.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYMTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            3225..3662
                     /locus_tag="VYP85_001996"
     CDS             3225..3662
                     /locus_tag="VYP85_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1882447.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVTTDEE
                     KAVAYLHDVIEDTTLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKTNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRTKKKS"
BASE COUNT         1490 a          519 c          653 g         1072 t
ORIGIN      
        1 tattgttgac aaatagaaaa tactgtgtta aaatgtctat ataacagaga cagttggagg
       61 tataagaatg agtcgtactt atataaatat aagacttgca tacgaaacca agtattggtt
      121 agaatgtata caagaagagg ttcaaaaaaa attagatgct ttaattaatg aacaagatat
      181 agaggagtta gaatcaatca tcactaataa gttagaaaaa aaagattctc tattgggggc
      241 tgtttccata acaacttttt tcaaggtatc ttcttcaagc gtgattgaaa aagcctataa
      301 cgagacaaaa aattacacta cttcagaatg gcgagaaatt gcaaggcaaa tgaatttggc
      361 aaaagttaag caaaacatgg aaattgggac gttaacacct agattatatt tagataataa
      421 tattatttca gaattagaga agtatcaatt tttattcaaa agtgatgata tgataaggca
      481 ggtaaggatg agctatgtta ttaaaatggt cgcatttgcc tactataaaa aattgtttgc
      541 atgatttata agctcgataa taagagctta taaaaataca acctttgtct gtgttaacga
      601 gacttttaaa ctttttaatc ggaaggagaa tattttgata ggagcgtcac ctattattta
      661 tttgacaaca ttaaataaaa actaatatta aaaaaatata aaggaggagc agaaatgcca
      721 aaattattag agactgaaaa atacagttta gatagcatta tagatggagg gaagcttaga
      781 atgatttcta agttttgccc agacttacat ggcttgaggt acgaattcaa aacatcagac
      841 tcaattacta aagaatattg taaaaaaata cgtcaagctt taagagattc tgatccagaa
      901 ggaaagagtg gaaaaaaatg tatgatgaga tatacaatag atattttaaa tgtatggaac
      961 acgctatgta gaacacgaga ttttataacg gggagtttaa aagcggatga tgttatagat
     1021 gggaagacag ggatatactt ctttgatgtt aatacgtcta atgtaattac ggatgatgtt
     1081 atagaaaatg ttaaaattaa tcacaaaagc ttagtacgaa atgttgatga agaaaatata
     1141 gaaagtattt caaaagaaat tcctaaaggt actgatatgt attattatgt tttgtataga
     1201 ttagggttga ataggattaa gtataattat ttagtcaagg ctctggcagg cgcaatacag
     1261 aaggattaag aatataatta tataattaag ggggagtttt ttctcccctt atagagatag
     1321 tattattctt ttggtatttg gggtatcgtt tatcaatctc atcttatagc taataaaaat
     1381 agtctatgtt tttagtgaaa aaaatattat tttaaggagt ggtgatatgt atatacttgt
     1441 cacaaatggg aaaagctacg tgactttccc ttggttgcgt gaaatagctt gcagaaatta
     1501 taaaggagaa actaaggtgt ttactacaaa ggaactctat aatttcctat attaaacgct
     1561 ttaactatca catttttaat accaagaaaa gtaaattaaa atatatagca gtattagaga
     1621 ggcaaaaacg taaagcatgg catagtcata ttttgctatt cagtgttccc tatattccac
     1681 ataagcaatt attagaactt tgggggcatg gagcagtacg gataaataaa gttgacgttg
     1741 acagcaaaga aaatcgcggt cgatatgtca caaagtattt tgaaaaaggt attggacaag
     1801 aattgttgga aaacttcgga aagcaagcct atttttcatc acgcaacttg aaaaagcctg
     1861 atgaagataa attttacact tatgaagatt ttaactatga tagttcagtc gtactatatg
     1921 aaacggaata caactgataa cccgaggctt tacagtctat cagaacaagc gaattggtac
     1981 tatacctgct actattgcta ccgaattact cggttttgat gttcaaaaca gtaccctcaa
     2041 ggagtaaaat atggcaatta gaaaaggtaa agacggtaat tgggtagttg atattagcaa
     2101 cggttttgac ccaataacac taaagcaacg tagacttgtc agaaagggat atatgacgaa
     2161 aaaagaagct attgaagcag aacactactt acgaagtgta gagttaaaag aacgcttcta
     2221 tggggctaaa ataactatct ccatactata tgaactactt aaggaagaag atagcataaa
     2281 tcatcgaaaa gcaagctata tcaatacaca agataataat tacaacaaac acatcaaaga
     2341 ttatttttct atggtcgata atgtcggaaa actaacctat gaagacatct accaatttag
     2401 agaacatctt aggcaaaaag tagctaaaaa ttctgataaa ccgttaagca caaatactat
     2461 taacaaaatc atgattttac tcaaaaaaat ttttgatgtt ggtttgcgaa aaggctatta
     2521 ctcctccaat ccagcaaaat tgataaaaaa gttgccaatt gaaaaaacaa aaatgcaatt
     2581 ttggacagtc aaagaatttc agaagttttt gacactattt gaacccgaag aatacaatat
     2641 caaactactc tttactgttc tattctttac aggattaaga cttggggaag ctcttgctct
     2701 aacatggcaa gacatcgact tttcaagtaa tacaattcat atcacgaaat ctgtctatgt
     2761 taataaagga gtaactcata tcagcacaac aaaaactaaa gcaggaacaa gaagaattgt
     2821 tatcaataaa aaattaagcc aagaattaca agattgggaa aagcgacaaa aacatctatt
     2881 agagcaattt accaacaata gcctaacatt acaagtgttt caaaatagtc ctatcacaat
     2941 tacaaaaaat gctattgaaa agcagtacaa gaaaatcatt gaacgtgata gtacactaaa
     3001 aaagatacgc atacacgatt ttaggcactc acacgcttcc ctgctgatta accaagggga
     3061 agattatcta gttgtaaaag agcgactagg acatgcttct ataacaacca cgattgatac
     3121 ctactctcac ttgtacccaa gtaagcaaaa ggatttagct gataaactag atgatttact
     3181 ataaagtaat tgagttttat aaatggaaag tttataatta aatcatggat acatcacaag
     3241 taataaaagc acatgaagta gctaaaaaag cacactttgg acaaattgat agagcaggaa
     3301 ttgactacat taaacaccct gaaacagtag ctagttttgt cacaactgat gaagagaaag
     3361 ctgtcgccta tctacatgat gtaattgaag atactacact aaccctacta gacctaaaaa
     3421 aggaaggttt ttcaaaaaac attatagaag cagtcgatat actcacaaag aaaaaaggac
     3481 aagattatca atcttatctc aatctagtaa agacaaatga acttgctaga gttgtaaaat
     3541 tggcggattt acggcataat tcagatttaa ccagactacc attaattact gaaaaagact
     3601 tagagagaaa taagaaatac agttctgcta ttagattttt aagaacaaag aaaaaaagtt
     3661 agtaactaaa ctataaaaat ttataaagag aaaacaaggc ttataaactt tgtctttatt
     3721 actatcttgg cggt
//
LOCUS       DAVMCN010000100         3421 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVMCN010000100 DAVMCN010000000
VERSION     DAVMCN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.101"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..175
                     /locus_tag="VYP85_001997"
     CDS             <1..175
                     /locus_tag="VYP85_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1882448.1"
                     /translation="NRTVSFAISSKGEKMKVENISYRVDHRILFDNISFATSSSGVTL
                     ITGKNGTGKSTLL"
     gene            complement(541..1851)
                     /locus_tag="VYP85_001998"
     CDS             complement(541..1851)
                     /locus_tag="VYP85_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1882449.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2088..2960
                     /locus_tag="VYP85_001999"
     CDS             2088..2960
                     /locus_tag="VYP85_001999"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1882450.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3091..3421
                     /locus_tag="VYP85_002000"
                     /pseudo
     CDS             3091..3421
                     /locus_tag="VYP85_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         1078 a          581 c          756 g         1006 t
ORIGIN      
        1 aaacagaact gtttcttttg ctattagttc aaaaggagaa aaaatgaaag tagaaaatat
       61 ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgcta cttcgagttc
      121 aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac tatagtagat
      181 tgaaactaga atagtacaca tctacttcta aaatattgtt agaaatcgat ttgactatcc
      241 tgatctattt gtcctgttct tatttcattt cactatatct caaattgagt atgacgaagt
      301 gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg aatccatcga
      361 taaagactat tgggatgaat ttttaaagtt gaactaatca tttttacagg atgagattta
      421 cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact tttcctcgtt
      481 tccacttaat tttgtgtcta ctttattata ccaagtccac ccttaagtta gataataaat
      541 ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca aacttaagct
      601 gatggggaca cccagaataa tttgcttttt gaaggcaagg ccacgttcct ctatattggg
      661 aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag tagatagagc
      721 gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt gagcactgat
      781 gatagcaatg atgggaaaga gggctggagc tacaacggat agggtggaac taaagagtga
      841 catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa tggttgttgt
      901 catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca ttagtaagct
      961 catgccgcag agcatgataa ttgtagccca gggaacctta gctaaaatgg cttcttgctt
     1021 ccctaatttg agccttaagg cgaggcagac catgagtatt gagacaaagc caatatcaaa
     1081 tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca acaagggaaa
     1141 aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct
     1201 gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac tatagtgact
     1261 gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga taaagatatg
     1321 attgccaagt gaaaaagctt gctcttccca tcccatttgc ttaaacaggc cttgaaagac
     1381 aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat tgacggcttg
     1441 agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta gaggacagca
     1501 aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg ccatcaggta
     1561 taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt gttgagccaa
     1621 aacatcaaga gtaccgttag ttgttgcaac gttataaaag agagagacgc taaaaatggt
     1681 aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc ccatgagagt
     1741 ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt tggtgcggta
     1801 accaattcca atggctagag caatggcgct aatcattatt aaatgaatca ttgaattgtc
     1861 ctttcagtta gaatatggaa atagattggc aattttggcg ctcaaaagac cacctgtttc
     1921 ctattggtac ttgactatta tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac
     1981 acttgttaga attaaaaatg aggtattcag gcttgtgatt tcctatggaa gttaatagta
     2041 attgcctcta gtgcttacaa gtgatattaa aaatagagga cttagtgatg tcaatcattt
     2101 caactgattt aacccctttt caaatagatg atacattgaa agcagccttg cgagaagatg
     2161 ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa gccaaggtgt
     2221 cgctttttgc caaggaagct ggtgttttag cgggactaac cgtttttcaa agggttttta
     2281 ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat ggggatcgtt
     2341 tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagtctc ttaacatgtg
     2401 aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg acagctgctt
     2461 atgtagaagc cttaggcgat gattgcatta aggtatttga tactcgaaaa actactccta
     2521 atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat catcgcttta
     2581 atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa
     2641 aggcaattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg
     2701 aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc atgttggata
     2761 atatgtcatt ggaacagatt gaacaggcta ttaccctaat tgcaggacgt tctcggattg
     2821 aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta gcgattgatt
     2881 acgtctccag tggtagttta acccatagtg ctaagagtct tgatttttcc atgaaggggt
     2941 taacctacct tgatgtctaa gttgtaaaat aaactaactt tttaaaggat gtttttcctc
     3001 tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatatagtaa aatgaaccaa
     3061 aaatagtaca caatgtggta taatcttttt atggcatatt caatagattt tcgtaaaaaa
     3121 gttctctctt attgtgagca aacaggtagt gtaacagaag cataacacgt tttccaaatc
     3181 tcacgtaata ccatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaaccac
     3241 caagtaaaag gaacaaaacc aagaaaagtt gatagagata gacttaaaaa ctatcttact
     3301 gacaatccag atgcttattt gattgaaata gcttctgaat ttggctgtca tccaactacc
     3361 atccactatg cgctcaaagc tatgggctac actcgaaaaa aaagaaccac acctactatg
     3421 a
//
LOCUS       DAVMCN010000101         3249 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVMCN010000101 DAVMCN010000000
VERSION     DAVMCN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3249
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.102"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(52..327)
                     /locus_tag="VYP85_002001"
     CDS             complement(52..327)
                     /locus_tag="VYP85_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1882451.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(433..1272)
                     /locus_tag="VYP85_002002"
     CDS             complement(433..1272)
                     /locus_tag="VYP85_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1882452.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1414..2262
                     /locus_tag="VYP85_002003"
     CDS             1414..2262
                     /locus_tag="VYP85_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1882453.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2355..>3249)
                     /locus_tag="VYP85_002004"
     CDS             complement(2355..>3249)
                     /locus_tag="VYP85_002004"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1882454.1"
                     /translation="NQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAARKDLLPIV
                     VMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQFASLTAQEF
                     FATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKGKISSTRIR
                     QAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYMPADGVYVV
                     DVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLDRIRDMTKF
                     DSVDQLVDQLKADEEVTRNWY"
BASE COUNT          973 a          682 c          524 g         1070 t
ORIGIN      
        1 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
       61 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      121 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      181 accaaaaccg atcaattgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      241 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      301 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      361 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      421 tttatttatt ttttaggagt ggtaacgtat caaaatagcc caagcgttct cacccgtgtg
      481 agtttgaata atggaacccg tttccaaaac agaaattggc ttttcaacat aagcttgtaa
      541 gctttctttc atctcttttg cccaatcatc actaccagaa tatgaaattc caatctctgc
      601 tacagcacgt tcagaaagcg atgttatcaa ctcatctaac cattttttaa atgttttagt
      661 tccacgacct ttaaccattg gctgcaattc atggtctttc atttgcatga caacacggat
      721 attgagaagg gagctcaaca agccagttac acggccaatt cgtccacctt tgacaagatt
      781 ttccaaagtt gaaacaccaa tataaagctc tgtatggttt ttaacctctt ctacatgaga
      841 taaaattgcc tccatatctt taccttcttg agctaacttc gcagcctcaa caacttggaa
      901 tttcagggct tggtcagtga aggaactatc aacaacagtc acatctgcag tagataggct
      961 agcaccttgg cgtgctgctt ctaccgtacc cgaaagagca tgggacatat gaatagcaag
     1021 aatctggcca ccatctttgc ataggtcttc aaaaatctca gcaaagacac ctacaggtgg
     1081 ctgacttgtt ttcggaagat tcttactttc ttgcatcaac tgaagaaatt taccttcttc
     1141 tttcaaatcc gcatcagaat aaacaacatt atcaatcatt acagataatg gaacaattgt
     1201 aatatctaat tgctttacta gttcaggttc aatagtaaca gatgaatcgg ttacaatctt
     1261 aatttttgtc atagtatcaa tctttctatt ttaggattca gattggtttc cttacttcta
     1321 attatatcaa aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt
     1381 gatataatca acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt
     1441 accattttac taggtgctgc tatttatgct tttggactga cttattttgt agttccccat
     1501 catctctttg aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc
     1561 cctgtttccc tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatc
     1621 tttggagcca aatccctcta ttctagttta ctaggaacct tagctttgtc cgcctggtta
     1681 gctttttttg agcatattcc ccttcatatt gatcttcaag gtgatttact aatcacagcc
     1741 cttatagcgg gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca
     1801 actggcggaa ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga
     1861 aaactgctct ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat
     1921 ttgagattgg tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg
     1981 attggtgaag gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa
     2041 cttgctaagg cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc
     2101 tactatagta aagaaaattt gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg
     2161 aaaacgaagg aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc
     2221 catgaaatcc taggagaagg cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga
     2281 cctcaaaagt tagactaaat catctatctt ttgggttaca gacaacctct tttttatttt
     2341 atttactcaa gctcttaata ccaattccga gttacttctt catcagcctt taactgatcc
     2401 actaattggt caactgagtc aaatttggtc atatctcgaa tgcgatcaag ccaataaacc
     2461 atgacggttt ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct
     2521 tcttctccat caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctt
     2581 tgaatctcaa catcaacaac ataaacgcca tctgctggca tataagtacg gtctaaaagc
     2641 actaaattcg ctgtcggata accaattgta cgaccacgag cattaccatg aaccaccata
     2701 cctcttgatg gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa
     2761 atagcttgac ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca
     2821 atgataactt ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca
     2881 aatgtataat caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca
     2941 aagaattctt gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct
     3001 tctacacctt cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac
     3061 aaatctggat gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg
     3121 ataggcaaca aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc
     3181 ttatgtatgc catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct
     3241 ttttggttt
//
LOCUS       DAVMCN010000102         3086 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVMCN010000102 DAVMCN010000000
VERSION     DAVMCN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.103"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            225..1511
                     /locus_tag="VYP85_002005"
     CDS             225..1511
                     /locus_tag="VYP85_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1882455.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            1526..1837
                     /locus_tag="VYP85_002006"
     CDS             1526..1837
                     /locus_tag="VYP85_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882456.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2083..2811
                     /locus_tag="VYP85_002007"
                     /pseudo
     CDS             2083..2811
                     /locus_tag="VYP85_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
BASE COUNT          959 a          531 c          664 g          932 t
ORIGIN      
        1 atgtattttt acgagtcagt atctttggat actggttttt acttttctag actttttgac
       61 tacttgttaa aactgggata attttcgact gtttaacagt tattatgcaa agtctaaaag
      121 attagaattg tcaaaacaat ccgtctaggc ttgattttat cctttattta ctataaaatg
      181 agaaggaaaa atgtcaaact tttatattgc aaataggaga aattatgaca aaaacattaa
      241 aacgtcctga ggttttatca cctgcaggga ctttagagaa gctaaaggta gctgttcagt
      301 atggagcaga tgctgtcttt atcggtggtc aggcctatgg tcttcgtagc cgtgccggaa
      361 actttacttt cgaacagatg gaagaaggcg tgcagtttgc ggccaagtat ggtgccaagg
      421 tctatgtagc ggctaatatg gttatgcacg aaggaaatga agctggtgct ggtgagtggt
      481 tccgtaaact gcgtgatatc gggattgcag cagttatcgt atctgaccca gccttgatta
      541 tgattgcagc tactgaagca ccaggccttg aaatccacct ttctacccaa gccagtgcca
      601 ctaactatga aacccttgag ttctggaaag agctaggctt gactcgtgtc gttttagcgc
      661 gtgaggtttc aatggaagaa ttagctgaaa tccgcaaacg tacagatgtt gaaattgaag
      721 cctttgtcca tggagctatg tgtatttcat actctggacg ttgtactctt tcaaaccaca
      781 tgagtatgcg tgatgccaac cgtggtggat gttctcagtc atgccgttgg aaatacgacc
      841 tttacgatat gccatttggg aaagaacgta agagtttgca gggtgagatt ccagaagaat
      901 tttcaatgtc agccgttgac atgtctatga ttgaccacat tccagatatg attgaaaatg
      961 gtgtggacag tctaaaaatc gaaggacgta tgaagtctat tcactacgta tcaacagtaa
     1021 ccaactgcta caaggcggct gtggatgcct atcttgaaag tcctgaaaag tttgaagcta
     1081 tcaaacaaga cttggtggac gagatgtgga aggttgccca acgtgaattg gcaacaggtt
     1141 tctactacgg tataccatct gaaaatgagc agttgtttgg tgctcgccgt aaaattcctg
     1201 agtacaagtt tgtcgctgaa gtggtttctt atgatgatgc ggtacaaaca gcaactattc
     1261 gtcaacgaaa cgtcattaac gaaggggacc aagttgagtt ttatggtcca ggtttccgtc
     1321 attttgaaac ctatattgaa gatttgcatg atgccaaagg caataaaatc gaccgcgctc
     1381 caaatccaat ggaactattg actattaaag tcccacaacc cgttcaatca ggagacatgg
     1441 ttcgtgcatt aaaagaagga ctcatcaatt tttataagga agatggaacc agcgtcacag
     1501 ttcgagctta agaaaggaaa aggaaatgat agaggcacag ggtttcttag tggataagca
     1561 aacaagatgc attcattacc atagcaagct ggatattatt gctttacaat gctatgattg
     1621 taaaaagtat tatgcttgtt atcggtgtca tgattcatta gaaaatcacc cttttgagcc
     1681 gtatccctta tctttgatac aggataagcc tattttatgt ggtgtttgtc taaaactact
     1741 aacatataag caatataaag aaagtttaag ttgccccttt tgtttttctc gctttaatcc
     1801 aggttgccaa aatcataagg aacgctattt taaatagcaa atcatctagt tttgaagtag
     1861 gagaaaactc aattccaaga gaaaatgaag taaatcttcc cacaataaaa cgcataatat
     1921 caagattgtt caatacctga tactatgcgt ttttaagatt ttaaagactt ttttccttta
     1981 tctggtattt tgactacttg ttaaaactgg gttaattttc aactgtttaa cagttattat
     2041 gcaaagtcta aaagattaga attgtcaaaa caatccgtct agagtatgcg tgatgccaac
     2101 cgtggtggat gttctcagtc atgccgttgg aagtacgacc tttacgatat gccatttggg
     2161 aaagaacgta agagtttgca gggtgagatt ccagaagaat tttcaatgtc agccgttgac
     2221 atgtctatga ttgaccacat tccagatatg attgaaaatg gtgtggacag tctaaaaatc
     2281 gaaggacgta tggagtctat tcactatgta ttaacagtaa ccaactgcta caaggcggct
     2341 gtggatgcct atcttgaaag tcctgaaaag tttgaagcta tcaaacaaga cttggtggac
     2401 gagatgtgga aggttgccca acgtgaactg gctacaggat tttactatgg tacaccatct
     2461 gaaaatgagc agttgtttgg tgctcgtcgt aaaattcctg agtacaagtt tgtcgctgaa
     2521 gtggtttctt atgatgatgc ggcacaaaca gcaactattc gtcaacgaaa tgtcattaac
     2581 gaaggggacc aagttgagtt ttatggtcca ggtttccgtc attttgaaac ctatattgaa
     2641 gatttgcatg atgccaaagg caataaaatc gaccgcgctc caaatccaat ggaactattg
     2701 actattaaag tcccacaacc tgttcaagct ggagacatgg ttcgagctct taaagagggg
     2761 cttatcaatc tttataagga agatggaacc agcgtcacag ttcgtgctta atgtagttgt
     2821 ttagttttaa aaaattatgc aaagctccat atacaacact taaacgagat taaagaatgg
     2881 cgaaatccct tgatgcgcaa gggattagct gtctttttta ttttttaagt gataaagtcg
     2941 gagcttaggt atcaaagcct atcaaattaa acaaagaagc gatgtcttag atattttgaa
     3001 aaaaattaat aagcagaaaa ctctctatta ttttgttgta gagagttttt tgttaataaa
     3061 attttacaaa atgacattta tatatt
//
LOCUS       DAVMCN010000103         3070 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVMCN010000103 DAVMCN010000000
VERSION     DAVMCN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.104"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(19..90)
                     /locus_tag="VYP85_002008"
     tRNA            complement(19..90)
                     /locus_tag="VYP85_002008"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55..57),aa:Glu,seq:ttc)
     gene            complement(152..1507)
                     /gene="rlmD"
                     /locus_tag="VYP85_002009"
     CDS             complement(152..1507)
                     /gene="rlmD"
                     /locus_tag="VYP85_002009"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1882457.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1545..2321
                     /gene="recX"
                     /locus_tag="VYP85_002010"
     CDS             1545..2321
                     /gene="recX"
                     /locus_tag="VYP85_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1882458.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYKGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2410..2943
                     /locus_tag="VYP85_002011"
     CDS             2410..2943
                     /locus_tag="VYP85_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1882459.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT          974 a          570 c          560 g          966 t
ORIGIN      
        1 tcctgacgca acataccata gtccgtacgg gattcgaacc cgtgttaccg ccgtgaaaag
       61 gcggtgtctt aaccccttga ccaacggacc tgagttgtta ttttcaactc ttactattat
      121 acagtctttt caaactttgt caactacttt tttaaacttt ttttattaat tttacaacag
      181 cttcagttcg agctgtatgt gggaacatat cgaccgactg gatataatga agatcataga
      241 cttctactaa gcgtaccaaa tcacgagcca aggtcgaaac attacaagaa atataaacca
      301 ttttttctgg tacataagta agaatagtat ctaataactt atcatccaga cctgtacgtg
      361 gtgggtcaac aatcaaagca tctgctcggt agccttcctt gtaccaacga ggaataatct
      421 cttctgccgt tccagcttca taatgagtat tgtcaaatcc cattctttta gcatttcgct
      481 tggcatcttc aatagcttct ggaataatat ccatacctct gagtgttttt actttctttg
      541 caaaggcaaa tccaatcgtt ccaactccac aataagcgtc aatcaaatgg tcttctttat
      601 caacatccag cgcttttact gcttcgctat agaggacttc tgtttgctca ggatttagtt
      661 gataaaaagc tcgaggggat agtgaaaatt cataattgag tacaccttct tgaatactct
      721 cttgccccca gataatctct gtcttttcac catatatctc actggtttta gctgtatttg
      781 tattaacagc tactgtcaca acttctggga aatctttaac caactctttt accaattgag
      841 ttaaattaag ctggcggttt gtaacaataa taatctgaac ctgtccggtc tttctcgcgc
      901 gtcggaccat aatagtacgg acacctagaa cttttctctc atccgtgatt ggaatctggt
      961 gataagtaag taattctgct aagcgattag caatcacttg ggtttcctta tcttgtacca
     1021 ggcagtcttt caactctact aaatagtgag agttttgtgc atataagccc gccttgacct
     1081 gatttttaaa ttttcgagtc tgaaattgta acttagctct gtaatatttt ggttcctgca
     1141 ttccaatagt tggacgaatt tcataatttt catatcctgc aggagcaaat tttttcagcg
     1201 cttgatgaag taagtccgtc ttgaactcca gctgcttatc ataatgcagg tgcatgattt
     1261 ggcagcctcc gcattcatta taaatagtac aagatggcac aattcgaaat ttagacttct
     1321 tgttgacctt cagtaatttt gcttcaacaa agttgcgtct aatagaagta atctgacaat
     1381 agatatcttc gcctttgaga gctcctggta caaagactaa tgttttttgg taaaagccga
     1441 ttccctcacc gttaattccc atgcgcttga tttttaatgg tattttttgt ttcactttca
     1501 gattcatacc cctatcttat cacattttga gttataatag agctatgaaa atcacaaaac
     1561 ttgaaaagaa aaaaagactc tatctgatgg agcttgataa tggcgacaaa tgctatatca
     1621 ccgaagacac aattgttcgt tttatgttat cgagagataa ggtgataagc gaagaggaat
     1681 tgaaagagat tcaagacttt gctcaatttt cttatggtaa gaatctggcc ctctaccact
     1741 tatcctttaa agcacgtact gaaaaagagg tcagagaata tctgaaaaaa tatgatatta
     1801 atgaaaacat cgtttctcaa gtcattgcta atcttaaaga agagaagtgg attaatgata
     1861 gccagtacgc ttatgctatc atcaatgcca atcaactttc aggagacaag ggaccttatg
     1921 tactgactca gaaattagca caaaaaggaa tttcaaaatc tactatagaa gaaatcttga
     1981 atgattttga tttttcggaa gttgctcaac gtgtagccaa taaactattg aaaaaatatg
     2041 agggaaaact tccagctcgt gccctgcaag ataagattat ccagaacttg actaacaagg
     2101 gcttctctta ttttgatgct aaaattgcct ttgacgaatt ggatagtcaa gttgatgaag
     2161 aaacgactca ggaactcatc ttcaaggaac ttgataagca atatactaag tatgcccgaa
     2221 agtataaagg atacgaactg aagcagcgtt taactcaagt tttagcacga aagggctacg
     2281 atttttcgga tatagcaagc gctcttagag aatatcttta atatttccaa gtgaaattca
     2341 cagattttgg gtaattttat ggtacaatag taaatgataa acttataaat tgtagaaagt
     2401 tggttagtta tgaagcttcc aaaagaaggc gactttatta caattcaaag ttataagcat
     2461 gatgggagtc tccaccgaac ttggcgggac accatggtac taaaaacaac agaaaacgcc
     2521 attattggtg tcaacgatca tacacttgtt accgaaagtg atggtcgtcg ttgggtcact
     2581 cgagaaccgg ctattgttta ctttcacaag aaatattggt ttaatatcat tgccatgatt
     2641 cgtgataatg gaacttctta ctattgcaat atggctagcc cctactatct ggatgaagaa
     2701 gcactgaagt atattgatta cgatttggat gttaaaattt ttacagatgg ggaaaaacgt
     2761 ctcttggacg ttgaagagta cgagcgtcac aaacgcaaaa tgaattattc tgatgacttg
     2821 gactatattt taaaagaaca tgtcaaaatt cttgttgatt ggattaacaa tggacgtggt
     2881 cctttctcag aagcctatgt aaacatttgg tacaagcgct atgtagaact aaagaatcgg
     2941 taaagttgtc aaaggtcagg aacaaaatcc tgaccttttt tggtagtata aaataaattg
     3001 tgtaaacaca aaaaggaata aatctattat agcagagtta caacacatta ctagaaagag
     3061 atttatgcag
//
LOCUS       DAVMCN010000104         2958 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVMCN010000104 DAVMCN010000000
VERSION     DAVMCN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.105"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            69..191
                     /locus_tag="VYP85_002012"
     CDS             69..191
                     /locus_tag="VYP85_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV1882460.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATKSRAVPIYQTTSFVFDDT"
     gene            213..1328
                     /locus_tag="VYP85_002013"
     CDS             213..1328
                     /locus_tag="VYP85_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1882461.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKINYPKLADSPYYALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATITHGQLS
                     EKDLEAAGVTPNQIHLSIGLENVEDLIEDLRLALEKI"
     gene            1424..2698
                     /locus_tag="VYP85_002014"
     CDS             1424..2698
                     /locus_tag="VYP85_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1882462.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            2710..>2958
                     /locus_tag="VYP85_002015"
     CDS             2710..>2958
                     /locus_tag="VYP85_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882463.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNK"
BASE COUNT          946 a          537 c          651 g          824 t
ORIGIN      
        1 actgatattt gtaaactata actcaaggtg ctacaatatc cttaataaaa taatatggag
       61 gtcaccttat gactcgtgat tttaaatttg aaactctaca actacatgct ggtcaagttg
      121 tgactccagc tactaagtct cgtgcagtgc cgatttatca aacaacatct tttgtttttg
      181 atgacacgta ggaaggtgct gatctgtttg ccttgaggaa accagggaac atttatactc
      241 gtatcaccaa tcctacaaca gctgcccttg aaggtggtgt tgaagcgcta gcaacagcat
      301 caggtatgac tgcagtgact tatacgattt tggcgcttgc ccatgctggt gaccatgtag
      361 tggctgcttc gactatttac ggtggaacct tcaatctttt gaaagaaccc cttcctcgtt
      421 atggtatcac aacaaccttt gtcgatgttg ataatttgga ggaagtagaa gcagctatca
      481 aagacaatac caagcttgtc ttgattgaaa ccttgggtaa ctccttgatt aatattccag
      541 acctggaaaa actggcagag attgctcata aacatcaaat cccacttgtg tcagacaata
      601 cttttgcaat accttatttg attaacgtct tctctcatgg cgttgacatt gccattcact
      661 ctgcgactaa gtttatcggt gggcatggta caactattgg aggaataatt gtcgatagtg
      721 gtcgttttga ctggatggct tcagggaaat tccctcaatt tgttgacgag ggttcaagct
      781 gccacaattt gagctatact cgtgatgtgg gtgcagtagc ctttattata gctgttcgag
      841 ttcaattgct tcgtgataca ggtgcagcct tgtcaccatt caatgctttc ctcttgctac
      901 aaagacttga aaccctttca cttcgtgtgg aacgccatgt acaaaatgct gagacaattg
      961 ttgattttct tgtcaaccat cctaaggtag aaaagataaa ttatccaaaa cttgcagata
     1021 gtccttatta tgccttggct gagaaatact tgccaaaagg tgtcggttca atctttacct
     1081 tccacgtcaa aggtgacgag gaggaagcac gcaaggtcat tgataattta gaaatctttt
     1141 ctgaccttgc aaacgcggca gatgctaaat cgcttgttgt ccatccagca acaatcactc
     1201 acggtcaatt gtcagaaaaa gacctagaag cagcaggtgt cacaccaaat caaatccact
     1261 tgtctatcgg tcttgaaaat gtagaagatt tgattgaaga cttacgcttg gccttggaaa
     1321 aaatttaaag taaaagaaga taaacagtgg gttttgactc actgtttttg attttccctc
     1381 aggcatgata taatggttac agaagtctag aaagaggaat gtaatgaacg aaatcaaatg
     1441 tcccaactgt ggggaagtct ttacagtaaa tgaaagccag tatgctgaac ttttgtccca
     1501 agtgagaacg gcagagtttg ataaggaact acacgatagg atgaggcagg aactggcctt
     1561 ggctgagcaa aaggctatga atgagcaaca gactaaactg gctcagaagg atcaagaaat
     1621 tgcgcaattg cagagtcaaa tccaaaactt tgatacagaa aaagaattgg ccaagaaaga
     1681 agttgaacag acaagccatc aggccttatt ggctaaggac aaggaagtac aggccttgga
     1741 aaaccagttg gcgaccttgc gtttggagca tgaaaatcaa ttgcaaaaga ccctttctga
     1801 cctagaaaaa gaacgcaatc aggtcaaaaa tcagctccta ctgcaagaaa aggaaaatga
     1861 gttgtctttg gcttctgtta agcaaaacta cgaagcccag ctcaaagcag ccagtgaaca
     1921 agtcgagttt tataagaatt ttaaggctca acaatctaca aaagcgattg gggaaagcct
     1981 agaacagtat gcagagagtg agtttaacaa ggttcgtagt ttcgcctttc caaatgctta
     2041 ctttgagaag gataacaagg tctcttcgcg tgggtctaaa ggggacttta tcttccgtga
     2101 gtgtgatgaa aatggagttg aaatcatttc tatcatgttt gagatgaaaa acgaagcgga
     2161 cggaacagag aagaagcaca agaatgcaga tttttacaag gaattggaca aggaccgtcg
     2221 ggagaagaac tgtgagtatg ccgttttggt gaccatgctt gaggctgata atgactactt
     2281 taacacaggg attgttgacg tcagtcacga gtatgaaaaa atgtatgttg ttcgtcctca
     2341 attctttatc caattgattg gtctcttacg taatgcggcg ctaaattccc taaaatacaa
     2401 gcaggagttg gccttggttc gcgagcaaaa tattgacatt acgcattttg aggaagactt
     2461 ggatgccttt aagctagctt ttgctaagaa ctataattca gcttcgacta actttggaaa
     2521 agctattgat gaaatcgaca aggccatcaa acgcatggaa gaggttaaga aattcctgac
     2581 tacatctgaa aaccaactcc gtctagctaa caacaaattg gaagatgtct ctgttaaaaa
     2641 attgacccgg aaaaatccaa caatgaaagc gaagttcgaa gcattgaagg gggagtgagg
     2701 aaataagtta tggaagatga tcttaattat gaaaatttga tggatgatgt aaccgaggct
     2761 ataaaaaagt ttaacttagt aatttttatt ggcgcaggag tttcaattgc tcaaggttat
     2821 cctaattgga acaattatat tgaacatctt attaagtatt ggcaaggaca agttttatcg
     2881 gtaagtggtg aaaaaaggct tggaagagaa catcacgtag tttttgattt aattagcaaa
     2941 tctagtatta gtaataaa
//
LOCUS       DAVMCN010000105         2891 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVMCN010000105 DAVMCN010000000
VERSION     DAVMCN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2891
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.106"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            422..769
                     /gene="ssrA"
                     /locus_tag="VYP85_002016"
     tmRNA           422..769
                     /gene="ssrA"
                     /locus_tag="VYP85_002016"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1013..1789)
                     /locus_tag="VYP85_002017"
     CDS             complement(1013..1789)
                     /locus_tag="VYP85_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HEV1882464.1"
                     /translation="MNATDIKNTYLNYIKENAVFNDVTDTHTEVITPFIDPLGEAIGF
                     SIKSNGKHLTVTDDGYTIWNLSINNIDVTKKGRRQDIFNSLLHFNGFDLHDGAIERTT
                     GKEHLGQVIHDMTQLLMNVYDFIQLTPNNIKSQFLDDVKSYFMKNEHYTVFPAFSIAG
                     KSRLEHRFNFVFMSKGISKIARVHNNITKQQVDTILASWLDTSEYRRKEYGDTEQLYI
                     IVSDEGYNNIKDDHQIALQEYGINILNFSDKEQLEIQLGK"
     gene            complement(1816..2286)
                     /locus_tag="VYP85_002018"
     CDS             complement(1816..2286)
                     /locus_tag="VYP85_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882465.1"
                     /translation="MKELLLTDSEAKALIKIIKAIANKHNRTLTNRSSGTINLVGKHD
                     TRFILNYFYSTTSKVFHLRETQHNYTLLRINLNNKFHKNANGEKVWGNRVNIFSEEEY
                     YQKGDETTHYKAYPLPYEDILNTDDFLDMLDNLLDYTNVNNPENIAINIQEDLL"
     gene            complement(2341..2805)
                     /locus_tag="VYP85_002019"
     CDS             complement(2341..2805)
                     /locus_tag="VYP85_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HEV1882466.1"
                     /translation="MSKVVKVTGAEVVISHNEEYLKVNPSELNFVPKLGDEVEVHKVD
                     GEIIVIKVKDKKDDKININIVNENNAMQNQSQVVHTQEIATGVHYVNKWVYVILALFL
                     GGLGIHHFYAGYNGKGFLFLILSLTGIPAIIALFQGIIALFKKPDVYGRIAV"
BASE COUNT          854 a          459 c          491 g         1087 t
ORIGIN      
        1 aaatcgattt gactgtcctg atctattcgt actattctta tttcatttta ctatattttg
       61 gtgcaataag tgaaaagtag tccgaataat ataaggattg attttatagt ttttaaactc
      121 aaatgaatta aaataaagag agtacgaaaa ttctcatctg aaagtatttt agaataattc
      181 tcttcgtgaa tttcttcaaa acagatagct tcatcttagg tatgtgttaa ttggatttcg
      241 taagctctat ttacaatcgt aaagttatgc actgaaaaag ttgtagttag tcttccagtt
      301 tgctaaattt ctcgaatagt atctttttta ggtatgtgat ttttaggtat gtgattttta
      361 ggtatgtgat ttctttttgc atttttgagt tagataaggt ataatggttt tattgtcttt
      421 tggggtcgtt acggattcga caggcattat gaggcatatt ttgcgactcg tgtggcgacg
      481 taaacgctca gttaaatata actgcaaaaa ataacacttc ttacgctcta gctgcctaaa
      541 aaccagcagg cgtgacccga tttggattgc tcgtgttcaa tgacaggtct tattattagc
      601 gagatacgat taagccttgt ctagcggctt gataagagat tgatagactc gcagtttcta
      661 gacttgagtt atgtgtcgag gggctgttaa aataatacat aacctatggt tgtagacaaa
      721 tatgttggca ggtgtttgga cgtgggttcg actcccaccg gctccattat tcctttgcat
      781 tcttttgcat tccttggtaa aacgttgtta aatcaacgtt ttttattttt atctttggta
      841 ttcctttgca ttcttttgct aaaaagggag tcacaaacag accctatttt aaaaaaagga
      901 tagaaaaaag gatacaacat ttgtcgcatc ctagaaatct atgtacttcg taaagcgttc
      961 tccgattcga gtattcctct gcatgcttta gtaaatatag gattttttgt agttacttcc
     1021 ctaattggat ttctaattgt tctttatctg agaaattcaa aatgttaata ccatactctt
     1081 gtagagcgat ttgatggtca tctttgatat tattataccc ttcatcgctt acaatgatat
     1141 acaactgttc tgtatctcca tattcttttc tacggtattc agatgtatct aaccaactag
     1201 ctaagatagt atcaacttgt tgtttggtta tgttattgtg aactctggct atttttgaaa
     1261 tacctttact cataaacaca aaattaaagc ggtgttctaa acgagattta cctgcaattg
     1321 agaaagctgg aaagactgtg taatgctcat ttttcatgaa gtaagattta acatcgtcta
     1381 aaaattgaga tttaatattg ttaggtgtta gctgaataaa gtcataaaca ttcatcagca
     1441 attgtgtcat atcatgtatg acttgtccta gatgttcttt accagtcgtc cgttcgattg
     1501 ctccatcgtg taaatcaaat ccattaaagt ggagaagtga gttaaagatg tcttgacgtc
     1561 gccctttttt tgtaacatca atattattaa tggataaatt ccagatagta taaccatcat
     1621 ctgtaactgt caaatgtttt ccattgcttt ttattgagaa accaatagct tcacctaatg
     1681 ggtctataaa aggagtaatc acttcagtat gagtatcagt cacatcgtta aaaacagcgt
     1741 tttcttttat gtaatttaga taggtatttt tgatatcagt agcattcatg atattctcct
     1801 ttctttatag ggtgattata acaaatcctc ttgtatatta attgctatat tttcaggatt
     1861 gttcacattg gtatagtcaa gcaaattatc aagcatatcc aggaagtcat cagtgttaag
     1921 aatatcttca taaggtagtg gataggcttt gtaatgagtt gtttcatccc ctttttgata
     1981 atactcttct tcagagaaga tgttaactcg attgccccaa actttctcgc cgtttgcgtt
     2041 cttatggaat ttattattta gattgattcg taagagagta tagttgtgtt gagtttccct
     2101 tagatgaaaa actttgcttg tagtgctgta gaagtagttc aaaataaatc tagtatcatg
     2161 cttgccaaca aggttaatag tacctgaact gcgattcgta agagttcgat tgtgtttatt
     2221 agcaattgct ttaattattt ttatgagagc tttagcttca ctatctgtca gaagtaactc
     2281 tttcatatct ttcctttcta ctttatctac attctagaga gtggaaatct ggaatgtaga
     2341 tcagacagcg atccttccgt atacatctgg tttcttaaag agagctatga tgccttggaa
     2401 aagtgcaata atagcaggta ttcctgttaa agataaaatc agaaaaagga aaccttttcc
     2461 gttatatcct gcgtaaaaat gatgtatacc caatccacct aaaaataaag caagaataac
     2521 ataaacccac ttattaacat aatgtacacc tgtagctatt tcttgagtgt gaacgacttg
     2581 tgactgattt tgcatagcgt tgttttcatt gacaatgtta atattaattt tgtcgtcttt
     2641 tttatcttta acttttatga cgataatctc accatctact ttatgaactt cgacttcgtc
     2701 acctaatttt ggaacaaaat tcaattcaga tggatttact tttaaatact cttcattatg
     2761 ggagattaca acctctgctc ctgtaacttt aacaactttt gacattttgt ttttcctttc
     2821 attttaccat ctatagattt taataatgag ctttgatatt tattttatct gtttttataa
     2881 gtaaagtata t
//
LOCUS       DAVMCN010000106         2858 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVMCN010000106 DAVMCN010000000
VERSION     DAVMCN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.107"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            111..797
                     /locus_tag="VYP85_002020"
     CDS             111..797
                     /locus_tag="VYP85_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1882467.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIYDEHFLSQYAFCLVAEKSKRKSLILGVITCK
                     KIGNMLHLKS"
     misc_feature    806..893
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            930..1244
                     /gene="rplU"
                     /locus_tag="VYP85_002021"
     CDS             930..1244
                     /gene="rplU"
                     /locus_tag="VYP85_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1882468.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            1260..1604
                     /locus_tag="VYP85_002022"
     CDS             1260..1604
                     /locus_tag="VYP85_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1882469.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            1621..1914
                     /gene="rpmA"
                     /locus_tag="VYP85_002023"
     CDS             1621..1914
                     /gene="rpmA"
                     /locus_tag="VYP85_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1882470.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(2225..2431)
                     /locus_tag="VYP85_002024"
     CDS             complement(2225..2431)
                     /locus_tag="VYP85_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1980 domain-containing protein"
                     /protein_id="HEV1882471.1"
                     /translation="MTAFQQLPSSVLQTGLFFSPSVSLDSQTVSAKEYLFPYQKERAQ
                     TTQTSEGTTSQYLKPDSSFYSQLK"
BASE COUNT          890 a          496 c          579 g          893 t
ORIGIN      
        1 ttttagaaag aaaatggtac aatatttcta agagaaaata caatgggagg gaaaatgagg
       61 ttattaccta taagaaaaat atcacgtcag tctaaaaggt tagcactttt ttgacgtttt
      121 gtgctggata tgtggatgct tacactttta ttgttcgcgg gaataccctt gtagctggac
      181 aagctggaaa tgttgtcttt ctttcggtag agctcataca aaataatgtt tcggatatta
      241 gggataagct tttaacctta atagcgttta tgatgggagt ctttttatta acgatttata
      301 aggaaaaatt gagaattgtg aaaaaatcta ttctgtcctt gattccttta gcaatcctat
      361 caataattat tggttttgtg ccacaaactg tagataatat ctatctagtg ccgcccttgg
      421 ccttctgtat gggactggtg acaactgctt ttggtgaggt ttcgggtatt gcctacaata
      481 atgcctttat gacagggaat atcaaacgaa caatgctagc ttttggagat tatttccgaa
      541 ctaagcacac tccttttttg cgtgaagggt tcatatttgt tagcctgctt agtagttttg
      601 tccttggcgt tgtcttttca gtctatttga cgattttcta tcatgaaaag accattcttg
      661 gtgttcctat ttatgatgag cattttttat ctcagtatgc tttttgccta gtggcagaaa
      721 aaagtaaaag aaaaagcttg attttaggtg ttattacttg taagaaaata ggaaatatgc
      781 tacacttgaa gagttgacta tgcacgatcc tgtgcaaccg cacgaacatc gttgcttgat
      841 tattcaagtt taagtggttt gtcccacgat gctaggcgag tcttcacaaa aaaatcgggg
      901 aaacccataa aaatcatagg aggtgcataa tgagcacata cgcaattatc aaaactggcg
      961 gaaaacaagt taaagttgaa gttggtcaag cagtttacat tgaaaaattg aacgttgaag
     1021 ctggtcaaga agttactttt aacgaagttg ttcttgttgg tggtgaaaac actgttgtcg
     1081 gaactccact tgttgctgga gctactgtag ttggaactgt tgaaaaacaa ggaaaacaaa
     1141 agaaagttgt tacttacaag tacaaaccta aaaaaggtag ccaccgtaaa caaggtcacc
     1201 gtcaaccata tacaaaagtt gtcatcaacg caattaacgc ttaattttaa ggagaacaca
     1261 tgatacaagc agtctttgag agagccgaag atggcgagct gaggagtgcg gaaattactg
     1321 gacacgccga gagtggcgaa tacggcttag atgtcgtgtg tgcatcggtt tctacgcttg
     1381 ccattaactt tatcaattct attgagaaat ttgcaggcta tgaaccaatc ctagaattaa
     1441 acgaagatga aggtggctat ctgatggttg aaataccaaa agatcttcct tcacaccaga
     1501 gagaaatgac ccagttattc tttgaatcat ttttcttagg tatggcaaac ttatcggaga
     1561 actcttctga gttcgtccaa accagagtta tcacagaaaa ctaacacgga ggaaaacatt
     1621 atgttaaaaa tgactcttaa caacttgcaa cttttcgccc acaaaaaagg tggaggttct
     1681 acatcaaacg gacgtgattc acaagcgaaa cgtcttggag ctaaagcagc tgacggacaa
     1741 actgtaacag gtggatcaat cctttaccgt caacgtggta cacacatcta tccaggtgta
     1801 aacgttggtc gtggtggaga cgatactttg ttcgctaaag ttgaaggcgt agtacgcttt
     1861 gaacgtaaag gacgcgataa aaaacaagtt tctgtttacc caatcgctaa ataaaaaggt
     1921 ccattgaacc ttttatcccg aaccttgaaa tgtaaaggtg aggaagctag aaacagctta
     1981 aaataaggct ttccgagttt tcggagagcc tgtttttttg ttttgatacc catacttttt
     2041 aatatgtata gtggattgat actcttcgaa aatcaaattc aaaccacgtc agtttcacct
     2101 tgccgtactc aagtacagcc tgcggctaac ttcctagttt gcactttaat tttcattgag
     2161 tatgaatctg gaatagaaca ctgttaaaaa ttgatatgag tttcctactc gatttcttca
     2221 gattttattt caattgacta taaaaactgc tatctggttt caaatattgg cttgtcgtcc
     2281 cttcacttgt ctgagtggtt tgagcccgtt ccttctgata agggaaaaga tattctttag
     2341 ctgaaacggt ctgagaatcc aagctaacag atggagagaa aaatagccca gtctgaagca
     2401 cactagatgg aagttgttgg aaagcagtca tctagttttt ctttactgct ttggcttttt
     2461 ttgtcatcag ggaaagtgac ttgcttcaaa tcagggagtt taggaaattc ttcaaacatc
     2521 ttgcccaagt tgtctcattt tgtaaatttt acagccatag gtgtacctcg attctaaatt
     2581 ctaccttttc ggcaccaatt agtaatttaa agttctcagg agttagttgc attgcttttt
     2641 catacataag catagtatga cactttatgg ttaccgaaca agtctaatca ctccttgcaa
     2701 aattttgaag atgtcctaca agtttttgag aagaatattg caaagttcat agttaagcaa
     2761 cgatagaata aagtgctttt tgaaaacagg tacacttcat gtgaaaaaaa acaacatttc
     2821 agattttctg ttccagaaat agctatcgct atgatata
//
LOCUS       DAVMCN010000107         2731 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVMCN010000107 DAVMCN010000000
VERSION     DAVMCN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.108"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(1..546)
                     /locus_tag="VYP85_002025"
                     /pseudo
     CDS             complement(1..546)
                     /locus_tag="VYP85_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(639..797)
                     /locus_tag="VYP85_002026"
     CDS             complement(639..797)
                     /locus_tag="VYP85_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1882472.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(868..1297)
                     /locus_tag="VYP85_002027"
                     /pseudo
     CDS             complement(868..1297)
                     /locus_tag="VYP85_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1392..1832)
                     /locus_tag="VYP85_002028"
     CDS             complement(1392..1832)
                     /locus_tag="VYP85_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1882473.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            1823..2131
                     /locus_tag="VYP85_002029"
                     /pseudo
     CDS             1823..2131
                     /locus_tag="VYP85_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2286..2609)
                     /gene="tnpB"
                     /locus_tag="VYP85_002030"
     CDS             complement(2286..2609)
                     /gene="tnpB"
                     /locus_tag="VYP85_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1882474.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
BASE COUNT          825 a          568 c          505 g          833 t
ORIGIN      
        1 gccaagattt taccagcttg tctgatattt ctgcgactca ttttgaacaa cttcatatca
       61 tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt gacaatcgct
      121 tgagccttca tagcgtgaaa tttcttttta ccagaataat tcgctaattc tttttttagg
      181 gcgattgatt tttacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
      241 tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc tccgacggat
      301 taagttgctt tcgtgaatac caaaaacagc cgcaatttgt tcataagttc gatattctcg
      361 cacatattga agagtggcca taagaaggtc ttctagactt aatttaggtt ttcgtccacc
      421 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtcgt
      481 gcgttgaaca ccaacaagac gcttaaatcg tgcatcggtt agttgtttac ttgcttcatc
      541 attcatagaa ctattatacc atattttgtt tcgcaggaag tctattgaaa aatctccaga
      601 ctggagaact cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca
      661 actttagtcc atggtaaata agcctctaaa acctctttgt ttacgagagt ttcctcgttt
      721 ggaagacatt ctagaagata ggatagatat ttctcgctat ttaattgatg acgtttagct
      781 gtttccaaca aactcataat aatagctctt gctttagctc cttcaaaact ttgagaaaat
      841 aaccaccctc gcttttttaa actgagctta ggctaaaaga gtccactgga ctcttttact
      901 ccgtcccata accaatgatt taatggcgcg ttcagctaga ttattggaaa ggaccagatg
      961 tccgtctttc aaaatggtct taaaggtttc ttcatacttg aggctgtatt caattgccct
     1021 tcctagtttt gaacctgcta aaactgactg acgccggcac taagcaaaga agtcttccat
     1081 taagggctgg agatgttctt gacgtttctg tagtcgttca tcagctggca aagcctccca
     1141 gtctctttcc aaggaaaata actgatcaca ataagctaaa cctttagctc ctaaggatga
     1201 tttatccgct tgcttggggg ggcgcttcaa aaaacttcct tctcacatgc gcccaacatc
     1261 caacaagttc agcttcttcc agttgacgat aagcagacga gcggttcgaa gtttaccaag
     1321 cttagcgtcg ccttgctcct aaaccttgga ctgctatcgc ataggcagaa ctagaggact
     1381 aaagtcctaa gttactgccg caaaatatca caatgcacat agccagaata atctcctagg
     1441 aattcttgta ctactgaacc acttcgacac tgatcatggt ggtaaagcgt aatcccttgt
     1501 ttctctgctt tacctgacaa aaaagtccaa tagtaagtca gctgactatc actctctagc
     1561 accctataag aagtttcatc cgcatgaagt aagggctgag tcaatagtct ctctcgcaag
     1621 aggttataaa ggggctccaa atagtattga ctcgccttga tatgccaatt agagatttcc
     1681 ttacgtgtga ttggtaaacc catcctagcc caatcttctt cttggcgata attgggtacc
     1741 ttcagattaa acttctgatg gatggtgtga gcgataatag aagctgagcc aaagttatgc
     1801 gctaaagggg ctttaggaat aggagatttc acaagcttat ccagatgatt atcttttact
     1861 cgttatggac aatgctatat ggcataaatc aagtacctta aagattccga ctaatattgg
     1921 ctttgcattt attcctccat acacaccaga gatgaacccc attgaacaag tgtggaaaga
     1981 gattcgtaaa cgtggattta agaataaagc cttttaaact ttggaagatg tcatgaatca
     2041 actccaagat gttatacaag gactggagaa ggaggtgata aagtccatcg ttaatcggag
     2101 atggactaga atgctttttg aaagcagatg agtataaaaa gaaagtcctc atttcaatag
     2161 aaatcacgac tttctgatgg atttatagta aaatgaaata agaacaggac aaatcgatca
     2221 ggacagtaaa atcgatttct aacaatgttt tagaagcaga ggtgtactat tctagtttca
     2281 atctactata tttttggagt gatagaaaag cccttcataa gccagtctac ttgttctggt
     2341 gtgagagctt tgacatcctt ttctgtactt agccaaatca atctgccgtt ctcaaagcgt
     2401 ttatatagta gccaaaatcc ttgaccatcc cagtaaagga ctttaaagcg gtctttacgt
     2461 ccaccacaaa agagaaagac ttgaccggag aaaggatcca attcaaagtg ggttttaacc
     2521 agataagcca gtgaatcgat tccttgtctc atatcagttt tcccacacac gagatagacc
     2581 tcccctaggc tagatagatg aattgtcata gagcaacacc ttatccaaaa gctgttctac
     2641 catttcgaga ttgagagatt gaaaaaaact tacttcaagc ttgccaatac gaattttaag
     2701 cagaatatca tttctctttt tagaatcaaa a
//
LOCUS       DAVMCN010000108         2722 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVMCN010000108 DAVMCN010000000
VERSION     DAVMCN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.109"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..187)
                     /locus_tag="VYP85_002031"
     CDS             complement(<1..187)
                     /locus_tag="VYP85_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882475.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRD"
     gene            complement(245..958)
                     /locus_tag="VYP85_002032"
     CDS             complement(245..958)
                     /locus_tag="VYP85_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1882476.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIGRDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1417..1797)
                     /locus_tag="VYP85_002033"
     CDS             complement(1417..1797)
                     /locus_tag="VYP85_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1882477.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2219..>2722)
                     /locus_tag="VYP85_002034"
     CDS             complement(2219..>2722)
                     /locus_tag="VYP85_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1882478.1"
                     /translation="LYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRN
                     KNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESEEPQ
                     VETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLL
                     ALLKESK"
BASE COUNT          823 a          543 c          442 g          914 t
ORIGIN      
        1 aatcccttct cccaatataa tccccttctt tgactaatga tggagatttc caagtaaaaa
       61 ttaaatcgcc agagaaattt ttcttatcaa aaaacttaaa aagagattga taaatactat
      121 ttgctaattg acaagtgtca gatgtaaatt cataattaac agcttcatta aaatcaactt
      181 cagacatttc aatgtactct tcaatagtaa tattagcttt tttgtagtca ttagctcgtc
      241 tcctttaaaa tgtgatcttt tcaagaatat ttttatctaa acaatccagc aagtcttggt
      301 aagaatagac ttcgtaagtc ggctgggctt gtgtgtgatt ttcgaggtga tgaggattat
      361 accagatagt gtcaatcccc gcattattgc caccttgaat gtcggcggtt agagaatctc
      421 caatcatcag cgtcttttct ttactaaatc cagcaatttg ctggccaatc ttttcataaa
      481 aaagagcatc cggcttttga gtttgcaact gttctgagat aaagacttga ttgaaataag
      541 gtgctagacc agattgagcc aaacgtcctg tctgaatggc agtaatgcca tttgtcgcag
      601 catacaagtt ataatcacgc ccaatgaggc tgtccaagag atcatgagcg cccgatagtg
      661 tttgtccctg ctgggcgagg taaaattggt aacgctgggc aagaaaacta ccgtcttttt
      721 cttgtccaaa atgagcaaat aaacgagaaa agcgcgtgtt aaccagctct tgtttactga
      781 ttttcttcag ctccaagtct ttccagagag ccttgttcat aggaacgtaa taatctttat
      841 aagcctgaat atccgcaact ccttcttctt ttagaagttg ggtcaaagcc acatcctcag
      901 cagcatcaaa atcaagaaga gtgtggtcga ggtcgaagag tagaaatttg tagaacaatt
      961 tgaggttttc ctttctgaaa attcattaag aacattatat cataaagcac ctcatacaat
     1021 taactaattt aatcacttaa aaaaaattcg aacactttct atacaactga cagctcaaat
     1081 ctttcagaat agaacaatac taactatcga acaccctgtc ttcataaata catatgtaat
     1141 tctaggccta gaattcctat aaactaaatg ctttcatact cttccaagta attgattgcc
     1201 ttaaatttta atttttgaag gtttctaaag ctagaatagc cccatcacaa tcagttttga
     1261 ttgattcaca atttagaaac actatagttt cactcctgtt aaaataaaaa ggaactgcat
     1321 aaagcaatcc ctttctgatt ttgaaatcat ttacttaaca ttttatagtt gagataatca
     1381 atagcttatc tataaaaaga gttatagtaa aattccttat ttattgattt caagctccgc
     1441 taactgtatt tgaataactg acagttctgc accagcctga agaagagcag ctgcattata
     1501 ggcaccttct acaattggaa ccctgttgat gatgatactt ttatcactga aatcagtcac
     1561 catttttaag ttcattttag cagaacctag gtcaaaaaag gcaagtaaag tatctgctgg
     1621 attttcggaa acaaccctat ctacttgatc aaaactcgtt ccaattcctc cgccctcggt
     1681 tcctcctaca taagtaatcg gaacatcttt agctacttta ctaatcagtt caacaacacc
     1741 ttctgcaatg tgtttggaat gtgaaacgat aacaagacca ataccaatac tttccatcaa
     1801 accactccag tttctaaaat agcagtaaag agtaatcctg atgagaatga tccaggatca
     1861 atatgtccaa gaaaccacat gctcctaaga caagagctaa cagactggcc atcaataata
     1921 gtattgttct ttttttcatc attactcctt aactagtgtt taactgatta attagccagt
     1981 aaatagttta tctttattta cactatctgt taagatatag taaaatgaaa taagaacagg
     2041 acagtcaaat cgatttctaa caatgtttta gaagtagagg tatactattc tagtttcaat
     2101 ctactatatt ttgcacattt tcatgaaaaa aatgagaact agaactcaca ttctgctctc
     2161 atttttcgtt ttcccgttct cctatcctgt ttttaggagt tagaaaatgc tgctaccttt
     2221 acttactctc ctttaataaa gccaatagtt tttcagcttc tgccataata gtattgttgt
     2281 cctgggtgcc aaatagtaaa ttatttttta atcctgtgag agtctctttg gcattggact
     2341 tgataattgg atcctggatt tttccaagta aatcttcagc ctctctcagt ttttcttcaa
     2401 ccttttcagt ctcgacctga ggttcttctg attcctctgg tgattcttct ggttcctctg
     2461 ttggttttgg agactctggt ttctcgcttt gcggtttctc ttctcgaggg gtttcttcct
     2521 caggtttttc tgtctgaggt ttctcctcgc ttggtttttc cgtttgattg gtatcagctt
     2581 gaccattttt gtttctttga acatggtcgc tagcgttacc aaaaccatta tctgaatgcg
     2641 gacgttcgtt tggatgttcg acatagtact tgacagtcgc caaaagatcc tcaagagtat
     2701 accccttagg tgcctcataa ag
//
LOCUS       DAVMCN010000109         2214 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVMCN010000109 DAVMCN010000000
VERSION     DAVMCN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2214
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.110"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>2214
                     /locus_tag="VYP85_002035"
     CDS             <1..>2214
                     /locus_tag="VYP85_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1882479.1"
                     /translation="EKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHY
                     KYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQAL
                     VAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDY
                     ELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNF
                     VDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNL
                     ETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEIQENPDL
                     AEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIK
                     EQPETGVEHKDVQSGAIVEPAIQPELPEAVVTDKGEPEVQPALPEAVVSDKGEPEQVA
                     PLPEYTRPQAGAVVEPAIQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAPLPE
                     YTGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENE
                     ASSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDSSLK
                     YFMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYYLPK
                     TQQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGK"
BASE COUNT          847 a          365 c          444 g          558 t
ORIGIN      
        1 gtgaaaaaca agagcgtttt tcatttagaa aattatcagt aggacttgta tctgcaacga
       61 tttcaagttt attttttatg tctgtattag ctagttcatc tgtggatgct caagaaactg
      121 cgggagttca ctataaatat gtggcagatt cagagctatc atcagaagaa aagaagcagc
      181 ttgtctatga tattccgaca tacgtggaga atgatgatga aacttattat cttgtttata
      241 agttaaattc tcaaaatcaa ctggcggaat taccaaatac tggaagcaag aatgagaggc
      301 aagccctagt tgctggtgct agcttagctg ctctgggaat tttaattttt gctgtttcca
      361 agaaaaaggt taagaataaa acggtattac atttagtatt ggttgcggga ataggaaatg
      421 gtgtcttagt ttcagtccat gctttagaaa atcatctttt gctaaattac aatacggact
      481 atgaattgac ctctggagaa aaattacctc ttcctaaaga gatttcaggt tacacttata
      541 ttggatatat caaagaggga aaaacgactt ctgattttga agtaagtaat caagaaaaat
      601 cagcagccac tcctacaaaa caacaaaagg tggattataa tgttacacca aattttgtag
      661 accatccatc aacagtacaa gctattcagg aacaaacacc tgtttcttca actaagccga
      721 cagaagttca agtagttgaa aaacctttct ctactgaatt aatcaatcca agaaaagaag
      781 agaaacaatc ttcagattct caagaacaat tagccgaaca taagaatcta gaaacgaaga
      841 aagaggagaa gatttctcca aaagaaaaga ctggggtaaa tacattaaat ccacaggatg
      901 aagttttatc aggtcaattg aacaaacctg aactcttata tcgtgaggaa actatagaga
      961 caaaaataga ttttcaagaa gaaattcaag aaaatcctga tttagctgaa ggaactgtaa
     1021 gagtaaaaca agaaggtaaa ttaggtaaga aagttgaaat cgtcagaata ttctctgtaa
     1081 acaaggaaga agtttcgcga gaaattgttt cgacttcaac gactgcgcct attccaagaa
     1141 tagtcgaaaa aggtactaaa aaaactcaag ttataaagga acaacctgag actggtgtag
     1201 aacataagga cgtacagtct ggagctattg ttgaacccgc aattcagcct gagttgccag
     1261 aagctgttgt aactgacaaa ggcgagcctg aagttcaacc agcgttaccc gaagcggttg
     1321 taagtgataa aggtgaacca gagcaggtag ccccattgcc agaatataca agaccacaag
     1381 caggtgcagt agttgaacct gcaatccaac cagagttacc agaagctgtt gtaactgaca
     1441 aaggtgagac tgaggttcaa ccagagtcgc cagatactgt ggtaagtgat aaaggtgaac
     1501 ctaaacaggt agcaccgctt ccagaatata caggaccaca agccagcgct attgttgaac
     1561 cagagcaagt agcaccacta ccagaataca caggggtaca agccggatcg atagtcgagc
     1621 cagagaaagt agaagcaccg aaagaatata ctggtaaaat cgaacaacct agtgcagaag
     1681 atactaaacc tgaaaatgag gcaagctcta caaatgggga atcggaacgt cctaaagata
     1741 aaattaaaga agaaaaacaa gtcgacaaga aactagaact tagaaatgtt tcaaacgtgg
     1801 aattatatac ggtagaaaat aataaatatc gacatattac ggctgtagat ggtgctttag
     1861 atagttcatt gaagtatttc atgaaggtaa aatcagaaaa ttttaaagat ataatgttgc
     1921 ctgttactaa aattgaaagt acaacaaaaa acaataaaga agtatacaaa attgtggctc
     1981 atgcagaaaa tctaattcaa cacgaaaaca atgttatttc gaatgactat acatattatt
     2041 taccaaaaac tcagcaaagt gaaactggcg tctatacatc atttaaaaat ttagttgatg
     2101 caatgaatag tgaccctaat ggaacattcc atttaggtgc aactatggat gctcgtgaag
     2161 ttgaacttcc ggatgatcaa gaaagttatg taaaaaatga attttacgga aaat
//
LOCUS       DAVMCN010000110         2195 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVMCN010000110 DAVMCN010000000
VERSION     DAVMCN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2195
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.111"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(92..415)
                     /gene="tnpB"
                     /locus_tag="VYP85_002036"
     CDS             complement(92..415)
                     /gene="tnpB"
                     /locus_tag="VYP85_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1882480.1"
                     /translation="MMILLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(676..975)
                     /locus_tag="VYP85_002037"
     CDS             complement(676..975)
                     /locus_tag="VYP85_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1882481.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1140..1547)
                     /locus_tag="VYP85_002038"
     CDS             complement(1140..1547)
                     /locus_tag="VYP85_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1882482.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            1673..2195
                     /locus_tag="VYP85_002039"
                     /pseudo
     CDS             1673..2195
                     /locus_tag="VYP85_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          678 a          386 c          426 g          705 t
ORIGIN      
        1 gaaataagaa cagtacaaat cgatcaggac agtcaaattg atttctaaca atgttttaga
       61 agtagaggtg tactattcta gtttaaatcc actatatttg gggagtgata gaaaagccct
      121 tcataagcca gtctacttgt tcagatgtga gagctttgac atccttttct gtactgggcc
      181 aagtcagtct gccgttctca aagcgtttat atagtagcca aaatccttga ccatcccagt
      241 agagggcttt aaagcggtat ttacgtccac cacaaaagag aaagacttga ccggagaaag
      301 gatccaattc aaagtgggtt ttaactacat aggctaatga gtctattccc tgcctcatat
      361 ctgtcttgcc acaaacaagg tgaacttgac ctaaatcact tagtagaatc atcatagtac
      421 aatacctttc ctctgataat tattttttat ctagtatact ggaagttggg gaattaggat
      481 agataccttg ttatgacgcg cttacgtaac ttgtaactag ctgcctagtt tgatctttgc
      541 ttcttcattg attagcagca gatttcaaaa tgataaaaac gtataatagt gggtgtagaa
      601 actcttgtta ctatgcgttt tgttatggaa agacttattg gactttctct caaatcgagt
      661 ttttactcaa ttttcttact tgattgggat tgaaattcca attaatttct ctgagtagag
      721 tgtcttgata ttggcttcat caacagaggt cttatcaatt ttacgtttca agaaaaattc
      781 ttgaatggtt tcgatttcag gctcacgaat agcacggtgt ttgtttgaga tgaggatttc
      841 atagtgaagc ggagcttggg taaaaataac atctgtattc cctgcagaat aaacctcaac
      901 aagggttgca tcggtacttt ctagctgact ttttaccagt tgcgagtgtg agtttgtcgt
      961 attgataagc ttcataatat ttcctccgat tttctaattc tattatagca ctttttgaat
     1021 aaagtcgctt gatttatact caatgaaaat caaagagcaa actaggaaga tagccgcagg
     1081 ctatacttga gtacggtaag gcgacgctga cgtggtttga attttatttt cgaagagtat
     1141 tagccaatct tatgctgttt tttccaagat tcaatggccc atttatggct accacgttta
     1201 aggttttgga tagcctcgtc aatagggaac caggcaatat gattaaagtt ttctagtggc
     1261 ttttgtactt ctttgaaaga agttgcttca tagaggtagg caggattgta gtagtaggta
     1321 tcacgatgac gagaatagaa atattcgtca gcttgtccgt aataggtacc aatttctgct
     1381 gtgaaaccaa gctcttcaat caactcacgc tttagggctt cctgatgatt ttcacctgct
     1441 tcaatttctc cacatggtag gaaccaagca ccatttggtt cttgaacaag aacaatttgt
     1501 ttttgttcag gattagggat aactgcatat acgccatagc gagcaatata gtctgtattc
     1561 gctttttttc tccgaaagtt gggtttgcca ttgcattttc ctcattatct agtatcgtta
     1621 ttattatagt gaaatgaacc aaaaatagta cacaatgtgg tataatcttc ttatggcata
     1681 ttcaatagat tttcgtaaaa aagttctctc ttattgtgag cgaacaggta gtataacaga
     1741 agcatcacac gttttccaaa tctcacgtaa taccatttat ggctggttaa agctaaaaga
     1801 gaaaacagga gagctaaacc accaagtaaa aggaacaaaa ccaagaaaag ttgatagaga
     1861 tagacttaaa aactatctta ctgacaatcc agatgcttat ttgactgaaa tagtttctga
     1921 atttggctgt catccaacta ccatccacta tgcgctcaaa gctatgggct acactcgaaa
     1981 aaaaagaacc acacctacta tgaacaagag ccagaaaaag tagccttatt tcttaagaat
     2041 tttaatagtt taaagcacct agcacctgtt tagattgacg aaacaggatt cgatacttat
     2101 ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa gaagaggcaa agtatctgga
     2161 agaagatatc agaggatttc tttggttgca ggtct
//
LOCUS       DAVMCN010000111         2173 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVMCN010000111 DAVMCN010000000
VERSION     DAVMCN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.112"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            412..1389
                     /locus_tag="VYP85_002040"
     CDS             412..1389
                     /locus_tag="VYP85_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882483.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            1766..2140
                     /locus_tag="VYP85_002041"
     CDS             1766..2140
                     /locus_tag="VYP85_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1882484.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAATRYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
BASE COUNT          732 a          286 c          393 g          762 t
ORIGIN      
        1 ttgtttaaat tccagatgcg tgccatccca atatgataga tttttttata aagatagacc
       61 ttatattttt tccagaaaga gtcctattaa ggggtgaaaa tttgttacat ttggattaac
      121 aagtgtccta gggattagaa ataactctag tatagctaga tatttttgag taactagaaa
      181 tatcattagg ctacccatat gattgccaga aaagatggct gatgaatctt atttatactg
      241 ttgcagtagg cattgtctag gataaataag ctatcttgat gggggagatt ggaataattt
      301 tagtagaaac attaaaggat tatggacaag tagcgcagga ttaggtgatg caatgtgcta
      361 agttggcttg gtgttagcag tagtattatt taacaatgga aagtagacta aatgaaaaat
      421 aaacgttatt tttttgacac aattttaata attttactgc ttataagcac gatattttgt
      481 gtcagcccag tatttataaa attggacatc ttaggaactc cctctcatgc catcttaacc
      541 tttgtattgg cgataccgtt attctatatt ttgtctcaat gcttacatac tttgctatta
      601 ctagtttcct caatcttttg taaattaaga ccaatttatt tttattttat atttgtgatc
      661 attataggag ctaggaaata ctatcgaatt ctctttcacc aactaatggg atttagtcca
      721 ggaatagcag tgttttataa ggagagtcaa acaactaaga atctgtttaa attttactac
      781 ttcttgtact ttacaacact aatttcatac tattttttct ttacttttgt gtatgacaaa
      841 ccgttgcttt tgcctcttat tccattttct attatcatag cattagtaca aaaactttat
      901 agaattgaga atcaacaatt atttctgtta aaatcaaagg tactaacaat actggaatct
      961 aagagggatt gtgagtttaa tcttcaggat tatcatgaaa tttggaaatt gcaatcaaaa
     1021 tctgagttgc catgcgtggc tttatcttat atcagtttga tcaagccata tctttcagag
     1081 agcgtgcgtg aacaaattga tttattagaa gttaagcgat ttaaaaaaat aaatcatcca
     1141 atatcacttt atggtatgtt ggatgttata aaattaaatc tatatttacg gcattataat
     1201 gaaaaaaata aatatgaatc aatgttaaat aaaattttag aggtaagacc agactttgtt
     1261 ttaatcgagc agaatattga tgatagttta aatagctcgc aaccattatc tttatcttta
     1321 gccatttcag aaatccaact tttgcttgaa gtgtatatgg ggatcaaaca tgtttcaatt
     1381 aggagataaa accagaataa tatttgccat tataggggca agttgcatat tagtcagtat
     1441 gtatcttatt ccacttatta aaactgagaa taaattttgg gaaatacttt tatttatatt
     1501 aggtgtattg ctaattggaa ttgcgttatt aagtcaaaaa aaataaattt tgaaatagta
     1561 ttagtgagtt cgcaatcatt tattgctagt ggtttagaac tgttaagttt caaacaataa
     1621 ttgattttaa accttaggta acctataaaa acaaataagg tagagaaagg atatcttatc
     1681 taggtagcta agtgataaaa acacagtcgt ctatcacttg ttaggaaact atcctaacta
     1741 tgcttaataa aaaaggagaa aataaatgga actcgtatta ccaaataatt atgttgttct
     1801 tgagcaagaa gagatgatgt atcttgatgg gggattttct attccgagat ggcctgttgc
     1861 aacagccatt aatatagctt ttaatggtgt tttaggtgga ggagcaatca gtctagttag
     1921 aaattatatt cgtaattatg gtttgcggcg agttacaagc gcaattgctg gagcagctac
     1981 aagatatgtt ggggtacgag ttgcaaatag agtggcagga tttgcactgt ctgctattaa
     2041 tggatttgca gcttggatgt caattggcga tgctattaca acaatctggg ccaataatga
     2101 tgtaaatagg agagacccaa atttaaacgc cttgtggtaa ctagatatgg gtattaaaat
     2161 ggaaaaaatt ttt
//
LOCUS       DAVMCN010000112         2158 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVMCN010000112 DAVMCN010000000
VERSION     DAVMCN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2158
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.113"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            3..905
                     /locus_tag="VYP85_002042"
     CDS             3..905
                     /locus_tag="VYP85_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1882485.1"
                     /translation="MGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWS
                     FGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSS
                     LILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFA
                     KLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLT
                     AFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPV
                     GVVTGLLGSPYLIYLLIKMNRRNI"
     gene            905..1699
                     /locus_tag="VYP85_002043"
     CDS             905..1699
                     /locus_tag="VYP85_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882486.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT          798 a          330 c          359 g          671 t
ORIGIN      
        1 ttatcggaga tgaaagttat tctttttcaa ctttgattaa agtcttaaat agtgaaactg
       61 ttcctggagc tagtttttcg attatggaaa ttagattacc aaaattatta gcaggaatta
      121 tagctggctg gtcttttgga ttggcaggat ttatctttca aactatgtta agaaatcctc
      181 ttgcaagtcc tgatataatc ggtgtcacaa gttcttcatc tattgcagcg gtcttttgca
      241 tattggtatt aaaaacaaat agtttaacta ctggaattat ttcaataact tgtggactaa
      301 catcatcttt aatattattt ttactagcta aaaaagatgg tttttcagca gcaagactga
      361 taatattagg tattggtttt caagctgtca caagagcagg cacctcattt ttattgttga
      421 aagtagcaag atatgaatta caagaagtta tgagatggct cagtggctct ttatcttttg
      481 caaagttaga tgacatacct cttgttctaa tagtaagtat tattgctact atattagttt
      541 tattttttaa taaaagacta gaaattattg aacttggtga agaaatagca atcggacttg
      601 gagcaaatcc cgagctttca aggcttgttt taattttttg cgctgtatct ttaactgctt
      661 tttctacttc aattacagga ccaatagctt gtatatcttt tttagctggt cccatagcct
      721 taaatattgg caagaaaaga agcccaatat tagctggatt ggttggaatt ttactagttt
      781 tgttatcaga catattctct caaaatattt taccagctag atatccagta ggtgttgtaa
      841 ctggcttgtt aggttcacca tacttaatat acttactaat aaaaatgaac aggaggaata
      901 tataatgaaa ggtctgtggt caaataatct tacctgcggt tatgatgaaa aaataatctt
      961 ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg ggtcaaatgg
     1021 ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat tagagggaga
     1081 agtattgctt gataataaat caattaattc ttataaagaa aaagatttag caaaacacat
     1141 agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg atcttgtaag
     1201 ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg accttgaaat
     1261 aataaacaga tcaatggtta aggccaatgt tgaagatcta gcaaataacc tagttgaaga
     1321 actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc aagatacaag
     1381 tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa tagaactatt
     1441 agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga ttttgcacga
     1501 tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag gtaaacttgt
     1561 tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata tctttaatct
     1621 tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc ctattggcaa
     1681 gcaccatgtt agctcttaat aattgaatat cggaattcat ttaaaagtcg caaattttga
     1741 actgaccctc aaaagttagg ccaaaaaact aactaaagga ggtcagtttt ttaatggcaa
     1801 atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa aaataggata
     1861 tagataataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa gaaagtacaa
     1921 cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc tagaaaatac
     1981 tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag aaatatttat
     2041 taccgaaaaa aaggggaaat cgagtcaagt accaacaggc tcatctattc caaaaagata
     2101 tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg gtatctta
//
LOCUS       DAVMCN010000113         2031 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVMCN010000113 DAVMCN010000000
VERSION     DAVMCN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.114"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..1010
                     /locus_tag="VYP85_002044"
     CDS             <1..1010
                     /locus_tag="VYP85_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1882487.1"
                     /translation="LIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTI
                     LDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKELNGKAN
                     LFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLWRDMI
                     KIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWI
                     YTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTL
                     EALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNACKNA
                     K"
     gene            1000..2007
                     /locus_tag="VYP85_002045"
     CDS             1000..2007
                     /locus_tag="VYP85_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1882488.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
BASE COUNT          711 a          290 c          364 g          666 t
ORIGIN      
        1 ttctaatagc tattttagct atgtgtatag tttttagcgc ttgttcttct aattctgtta
       61 aaaatgaaga aaatacttct aaagagcatg cgcctgataa aatagtttta gatcatgctt
      121 tcggtcaaac tatattagat aaaaaacctg aaagagttgc aactattgct tggggaaatc
      181 atgatgtagc attagcttta ggaatagttc ctgttggatt ttcaaaagca aattacggtg
      241 taagtgctga taaaggagtt ttaccatgga cagaagaaaa aatcaaagaa ctaaatggta
      301 aagctaacct atttgacgat ttggatggac ttaactttga agcaatatca aattctaaac
      361 cagatgttat cttagcaggt tattctggta taactaaaga agattatgac actctatcaa
      421 aaattgctcc tgtagcagca tacaaatcta aaccttggca aactttatgg agagatatga
      481 ttaaaattga ttcaaaagcc ttaggtatgg aaaaagaagg tgatgagtta atcaaaaata
      541 ctgaagctcg tatatccaaa gaattagaaa aacatccaga aatcaaagga aaaatcaaag
      601 gaaaaaaagt attatttact atgattaatg ctgcagatac atcaaaattc tggatttata
      661 ctagcaaaga tccaagagca aattatttaa cagatttagg tctagttttc cctgaatcat
      721 taaaagaatt tgagagtgaa gatagttttg caaaggaaat ttctgcagaa gaagcaaata
      781 agataaatga tgctgatgta atcataactt atggtgatga taaaactctt gaagctttac
      841 aaaaagatcc tcttttaggt aaaataaatg caattaaaaa tggtgccgtt gctgtaattc
      901 cagataatac accgttagca gcctcatgca ctccaacacc actttcaata aactatacta
      961 ttgaagaata cctaaatctt ttaggaaatg catgcaaaaa tgcgaaataa aaaacaaata
     1021 aacctaggca taatttttgt aatctgccta ggtcttctta ttacaatatt tttgtcatta
     1081 aagcttggaa caaaagaaat taatatcaga gattttttag cagcttttgg aatgggtaat
     1141 acaaatgatg attttattaa atcaattata tataaaagaa tacctagaac tatttttgca
     1201 attttagcag gttctagtct tgccataagc ggtgtattga tgcaatcagt tactagaaac
     1261 ccaatagctg atccaggtat actcggtata aacacaggag caagtcttag tgtagtaatt
     1321 ggtctttctt ttttaggaat ttcatcaagc ataagccata taagttttgc aatcattggt
     1381 ggcttagtaa gtgcaatttt tgtatacgcg attgctgtaa gcggaaaagc aggccttacc
     1441 cctataaaac ttgccttatc aggaacttgt gttagtatgg ctttaagcag ttttgtaagt
     1501 tttttaattt taccgaataa taacgtctta gacaaattta gattttggca aataggtagc
     1561 cttggagcag ctacattatc ttctatatct acactactac cttttataat tttaggtcac
     1621 ttgatagcta tatttatttc atcagattta aacgctttag ctatgggtga tgaaatggct
     1681 gttggtcttg gagttaatgt taataggata agatcacttg caataattgc aagtgtgctt
     1741 ttatgttcaa gtattactgc aattggtgga cctattggct tcgtaggtct tatagttcct
     1801 cacttttgtg gcttatttat aagcaaagat atacgcacaa tgaccatttc ttcatctttt
     1861 ataggtgcag agctcttgct tatatgtgat ataatcggcc gtatgttagg taaaccaggt
     1921 gaaattgaag tagggataat tactgcaata atcgggggtc cagtacttat ttatgtaact
     1981 atgaaaaata gaggggttaa taactaatgc aaaatttaat tataggtatt c
//
LOCUS       DAVMCN010000114         2024 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVMCN010000114 DAVMCN010000000
VERSION     DAVMCN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2024
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.115"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(125..1336)
                     /locus_tag="VYP85_002046"
                     /pseudo
     CDS             complement(125..1336)
                     /locus_tag="VYP85_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(1338..>2024)
                     /locus_tag="VYP85_002047"
     CDS             complement(1338..>2024)
                     /locus_tag="VYP85_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HEV1882489.1"
                     /translation="NMITCDGYSIGSEIKRFYVHEYEELLFNTLSSSGYYLVRTSSLY
                     NDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIVFCEVGKRFGGGD
                     IPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATFALYRKQGKVIEV
                     PDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFEKRLDELKHISQK
                     FKYVITDSGE"
BASE COUNT          728 a          360 c          267 g          669 t
ORIGIN      
        1 tggtatcttg attgtattct tctaaaaagg attgcccttc acattcaact gtgattgatt
       61 aaattccaaa aatatattcc aaaggcgctc taaattctct atatcagcta ttttttatca
      121 tctatcaact tctatcatac ctcttcaata gcgtgctaaa tattagcgat aatatcgtaa
      181 tagatacacc aataataaaa aaattaaaag tattgttagg atttaaaact actgagaaaa
      241 aaacagtacc tagtggcata aaaagaatag ctaccgtaaa gatgattcca aatactctgc
      301 caagaaactc attatctacg tctctttgaa caatagagaa aaattggata ttaaaaatgg
      361 aaagaaatag actaaataat gctggagtaa aggctaaaat aatgacgttg cggaacatat
      421 aatagatcgg cgctgttagc attaacatca aacctgaata tgctaaaaag agcattaaac
      481 gtttgcttga caaggattta ttgataaatc cacttaatat cgcaccaata aagccaccaa
      541 tcgcttcggc tgttaaaaag gttccatata gcccacttga aatacttcca aacatttgat
      601 tactgtatgg cagcaacaaa ttataggctg ctaggaaaaa gttaacaagt gctgaaaggg
      661 caattatagt gagaatttgt ttatgactat atacatacgt aaatcctatt tttaaatcat
      721 caaagattcc tcttatcgtc atattctctt ttgtatccac ctcctcattt acaggagtaa
      781 tgaagaaaat tagtgaggca gcaattaaaa acgataatcc atctagtaat aacacaccat
      841 gtattccaag taacttatat aagaaaattg caatcatagg aattgttact ttaatcacag
      901 tacttgttgt ttctagcaat gaattaagtt atgatatact gtcctttttt acaatttctt
      961 tcgtaaaagc tttgtatgat ggccctgaaa aagcactcat aaaagccaaa atgacatttg
     1021 ttatgactat cgcataaacc aaccattttt cttgggatat aaatgaaaga gttatgcaag
     1081 caataccaca taagatattt gtagtaataa taattttttt ccgcttgaaa ctatctgcaa
     1141 taactccacc aaataaatta aatagaacac ctatcatact ttctaatgat tgataaattg
     1201 caaccactga tagagatgtt ggattaagac cagcaagaaa ggtattattg gcgaaatcaa
     1261 acatgatatc tccgattcga gatatcatcc tactagctac aatggataga atattgtgat
     1321 gttcttctct aatcatttta ttctcccgaa tcagtaatca catatttaaa cttttgtgat
     1381 atgtgcttaa gttcatctaa ccttttctca aattcacaac tatttttgca attaaattgg
     1441 accaacattg aattttcgac tacattttca gatactttat agtaagtatt tggtttaata
     1501 aatatgtaca ctttttttgc ccaagccaat tctttttcat caggtacctc gataacctta
     1561 ccttgctttc tatataaagc aaacgttgct gagatattag caggtctaga aatcacttta
     1621 gaaaaattta tttttttcaa tccttgtgaa ttagtcaaaa tatcccaata ttctttaatt
     1681 acatcaactc catgactatc ctcaattaac tggggaatat ctccccctcc aaatcttttt
     1741 ccaacttcac aaaagactat tttaccagtt gataattcaa ggaaccattc aaaatgaaaa
     1801 ggggttattt cagaattgat agaaaaaaca ttcaaaactt tgcgacattc ttccaatgct
     1861 ttttctatgt attcaatttt ttcactatca ttatataacg aactagtcct tacaagataa
     1921 tatccactag aacttaaggt attgaacaat agttcctcat attcgtgaac ataaaatcgc
     1981 ttaatctcac ttccaattga ataaccatca catgttatca tgtt
//
LOCUS       DAVMCN010000115         2006 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVMCN010000115 DAVMCN010000000
VERSION     DAVMCN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.116"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..224
                     /locus_tag="VYP85_002048"
     CDS             <1..224
                     /locus_tag="VYP85_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1882490.1"
                     /translation="TTLISVQFSQELNSLLNAIVEENNTTKTDFIRQAVIEKIEDMYD
                     IKVADEAYKKWVECGKKTISHEEMMRRYG"
     gene            217..948
                     /locus_tag="VYP85_002049"
     CDS             217..948
                     /locus_tag="VYP85_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1882491.1"
                     /translation="MAKIYAISDIHGYLDEFIDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(1059..1142)
                     /locus_tag="VYP85_002050"
     tRNA            complement(1059..1142)
                     /locus_tag="VYP85_002050"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1106..1108),aa:Leu,seq:caa)
     gene            complement(1152..1223)
                     /locus_tag="VYP85_002051"
     tRNA            complement(1152..1223)
                     /locus_tag="VYP85_002051"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1189..1191),aa:Gln,seq:ttg)
     gene            complement(1237..1309)
                     /locus_tag="VYP85_002052"
     tRNA            complement(1237..1309)
                     /locus_tag="VYP85_002052"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1274..1276),aa:His,seq:gtg)
     gene            complement(1324..1394)
                     /locus_tag="VYP85_002053"
     tRNA            complement(1324..1394)
                     /locus_tag="VYP85_002053"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1360..1362),aa:Trp,seq:cca)
     gene            complement(1399..1479)
                     /locus_tag="VYP85_002054"
     tRNA            complement(1399..1479)
                     /locus_tag="VYP85_002054"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1443..1445),aa:Tyr,seq:gta)
     gene            complement(1492..1564)
                     /locus_tag="VYP85_002055"
     tRNA            complement(1492..1564)
                     /locus_tag="VYP85_002055"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1529..1531),aa:Phe,seq:gaa)
     gene            complement(1568..1641)
                     /locus_tag="VYP85_002056"
     tRNA            complement(1568..1641)
                     /locus_tag="VYP85_002056"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1605..1607),aa:Met,seq:cat)
     gene            complement(1652..1741)
                     /locus_tag="VYP85_002057"
     tRNA            complement(1652..1741)
                     /locus_tag="VYP85_002057"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1703..1705),aa:Ser,seq:tga)
     gene            complement(1824..1897)
                     /locus_tag="VYP85_002058"
     tRNA            complement(1824..1897)
                     /locus_tag="VYP85_002058"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1861..1863),aa:Ile,seq:gat)
     gene            complement(1932..2002)
                     /locus_tag="VYP85_002059"
     tRNA            complement(1932..2002)
                     /locus_tag="VYP85_002059"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1968..1970),aa:Gly,seq:tcc)
BASE COUNT          662 a          413 c          389 g          542 t
ORIGIN      
        1 ttactacact aatttctgtt caatttagtc aagagttaaa ttctttatta aatgctattg
       61 ttgaagaaaa taatacaaca aagactgact ttattagaca agctgttata gagaaaattg
      121 aagatatgta tgatattaag gtcgctgatg aagcttataa aaaatgggtt gaatgtggca
      181 aaaaaactat ctcacatgaa gaaatgatga gacgctatgg ctaaaatata cgcaatatct
      241 gatatacatg gatacttgga tgaattcata gacgctctca ataaagtaaa tttaaacgat
      301 aaagataatc gcctattttt actaggagat tatcttgata atggacttca atcttttcaa
      361 gtcatttcca aaataatcga acttgaggag atttatccta atcaaattat tactcttcta
      421 gggaaccatg aagaatggtt ttatgattgg ttgattttag ataagcctac tgcttcagca
      481 tttccagaaa caataaaaag cttcttctct ccagaggaat tgaactatat ttttaaatcg
      541 aatgctaaca actttgaaac aggtgttaga aatgaaatta aaaataatat caaattcaac
      601 ccatttataa actggtttaa aaagcgatat agggataaac gctattatga aactgatacc
      661 caaatttttg ttcatgcagg cattgatgaa gaagcaggaa tgctttggaa agaactaacg
      721 agttcaaaga tatttacaaa caaatttcca attaccactg gtagatttca taaagctatt
      781 atttcgggcc atattgcttc ttgggaagta gctaaagata gaagatacct aggtaagatt
      841 tactatgata gtaaaagtca ttacttaatt gatggagatg taacgaatag caaaacaata
      901 cctgttcttt gctatgatac aattacccaa aaatatcact ttctataact tttagtcatg
      961 tgcttttata tgaaattagt aattattagt aacaattcca agaaatttct tatgacataa
     1021 caaaaagaca aggcttagaa accttgtctt ttcaactata ccggcggccg gggtcgaacc
     1081 ggcacgtcct tgcggacact ggattttgag tccagcgcgt ctgccaattc cgccacgccg
     1141 gcaaatagta actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg
     1201 ccttaccgct tggctatacc ccaataatat aaaataggcg agtgatgggg atcgaaccca
     1261 cgcatgccag agccacaatc tggtgtgtta accacttcac cacacccgcc ataattctat
     1321 taacacgggc agtaggaatt gaacccacac tgaaggtttt ggagacctta gttctacctt
     1381 taaactatgc ccgtaaaatg gaaggggagg gattcgaacc cccgaacccg aaggagcgga
     1441 tttacagtcc gccgcgttta gcctcttcgc tacccttcca aaatatataa atggcgcgag
     1501 acggaatcga accgccgaca catggagctt caatccattg ctctaccaac tgagctaccg
     1561 agccttattg cgggagcagg atttgaacct acgaccttcg ggttatgagc ccgacgagct
     1621 accgagctgc tccatcccgc gttaatataa aaggaggatg tgggattcga acccacgcac
     1681 gcttttacac gcctgacggt tttcaagacc gttcccttca gccggacttg ggtaatcctc
     1741 caaaatagtt tatacgggaa caagcccgtg tcctcttagt gaacagataa tattccaatc
     1801 ccctagtaat ggactaaaca ctatgggcac gagtggactc gaaccaccga cctcacgctt
     1861 atcaggcgtg cgctctaacc acctgagcta cgcgcccaag ttaaaaactt ggtacaaaga
     1921 acaaagttca aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtagt
     1981 tttaccacta aactacaccc gctaaa
//
LOCUS       DAVMCN010000116         1928 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVMCN010000116 DAVMCN010000000
VERSION     DAVMCN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.117"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..920)
                     /locus_tag="VYP85_002060"
     CDS             complement(<1..920)
                     /locus_tag="VYP85_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882492.1"
                     /translation="MKDDQKYLLAGFYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDA"
     gene            complement(1077..1322)
                     /locus_tag="VYP85_002061"
     CDS             complement(1077..1322)
                     /locus_tag="VYP85_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882493.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(1303..1665)
                     /locus_tag="VYP85_002062"
     CDS             complement(1303..1665)
                     /locus_tag="VYP85_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1882494.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
BASE COUNT          710 a          358 c          239 g          621 t
ORIGIN      
        1 gcatcttgta taccgccctc gaaagaacca tcttgtaatt ccgaaatatt tttgtttaaa
       61 tattgttttg acaaatctct taatgcttca ttatcgtaaa tgattcccaa aaatccaacc
      121 ttatatagta aataatttaa acttacaaag taattgaatc ccatagtata tttttcttta
      181 taaagcaaag gtaaaacttt ataaaaaata tctaagtcaa ccttactctg attctgaagc
      241 aagtaggagt caagcaaatt ttcaaaaata gctaacaata tgattggtgt aaggtttttg
      301 tattcacatg tcaagtattc cgagtatcgt gcagatgata tttcttttac ataacttttt
      361 gaaagcaaga ttttttcaaa ttcatcatct attattaatc ttctatttcc aatccaaacg
      421 gtattaccac ccaaataaga ttgtgcaaat agcaatatgt aagaaaacat gaacgtaaat
      481 actgaaagag gtagaattct atgcgtaaaa aaatagacga taatggtagc caggagtaaa
      541 gatatctctc gtgacaatcg aattcttttc agcatctttt ttaacagtcc gtaaggttgt
      601 ccttggcaat attcttgaac taaattaatc ggaatgacat ctctcaccat ttctggaaag
      661 tagagtaagt ttataggttg aaatctccag ctcccatcat aagtaaatgg atatagaacc
      721 aaatacttaa aagatttttt tcttataaac ttaattatca caatatgaat gactgttcca
      781 atgaagtata ttaaatataa aagtaaaacc gccatcaata tacttacaaa aatccccttg
      841 gaatcaatca atggaaaata aaatattgca actagaagcg aataaaatcc cgctaataaa
      901 tatttctgat catctttcat tcaaaacacc atattattta ctaagaatac atcaatacaa
      961 tagagcaact ctgtaagtca atatttgata aagcaaagct ttaaaccctt ccccagacgt
     1021 tagcttttat tcaacccact acagttgaca aggagcccaa attattgata aaaactttag
     1081 tcatcatcgt ctctataaaa atattttcta tacactcttg ataataccaa aattaatgcc
     1141 aatatcatac caagagctat aataatagaa tttattagat ttattttagt atatccaatc
     1201 actagtccaa taattggact ggtagacatg cttagatata ataaaaataa caaaaaatga
     1261 atttcaccaa ttcctgcaaa aaaatgtttc atagctatag ttttacgccc ataaatatcc
     1321 atcaaattta ccgtctacga tatctaaacc atatgcaatg gctcctccta atgagaagac
     1381 ttcagcaaca gtagccgcaa tattaagagc attagtaata gttgccatac taactccacc
     1441 aatatatctt gttatagcac ttctaacgac tcggctcatc ataccacgat tagcaattaa
     1501 ctttttaatg gcatatgtct ggtatactga catccctcca gaaactgcag ctgcagcaat
     1561 attatcacgt ttgttccacc agttacaacc aacaccaccc ccatcaagat acatcatctc
     1621 ttcttgctca agaacaacat aattatttgg taatacgagt tccatttatt ttctcctttt
     1681 ttattaagca tagttaggat agtttcctaa caagtgatcg ttgactttgt ttatagcact
     1741 tagttaccta gataagatat cctttagctt gcttccaaaa tttaagtctg cacctataat
     1801 atgagttcat attagtactg ctaaatccta tctatagtaa tgtcaaacac ctaaataaag
     1861 tcatctctcc gattcattca agaaatgaag aaaggcaaaa aatctttaaa ataagaaaaa
     1921 tgcatatt
//
LOCUS       DAVMCN010000117         1656 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVMCN010000117 DAVMCN010000000
VERSION     DAVMCN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.118"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            315..1178
                     /locus_tag="VYP85_002063"
     CDS             315..1178
                     /locus_tag="VYP85_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1882495.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYVPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
BASE COUNT          544 a          288 c          310 g          514 t
ORIGIN      
        1 taatagaaag taggttcttt gtaaccgctc cattataaaa tcctttcact cttccggtat
       61 actattagga aaaacataac tggaggatat tttgagctca cacctcatcg ttccagtggc
      121 tgttccccaa gctcgtgtac tgcccaaaaa agttagacat tctatttaga acgaggattg
      181 agttctgtat tgtacaaggc tcggtccttt tagagtcagc ttaaggctgg cttttttgcc
      241 ctcttaaata tcagaatatt ttgacaaatg attgtaaata atgatataat atgcaaaagc
      301 taggaggtgg tcagatgatt gagagaatgg aattgggaga attttacaag gaattgcgct
      361 tggcgagaaa acttaagcag tcagatgtgg cctgtgaggg tctaacagct tctcagttgt
      421 ccaagtttga actaggacag tctatgttat ctgcagataa gctcatatta gccatccaag
      481 ggatcaatat gaattttgat gagtttgggc acaagctcaa caactatcaa gaatctccac
      541 atatgcgaat cggtcgaaag gttgtggatc gctttgccca tcaggatata gctgctttag
      601 agcagctatt ggaggaagtc gatcaagaac agatggcgca gacctatcgt cgtttgaatg
      661 ccattgtgat taaaaatgca ctccattcct tagataaaag ctacccgcta acagaggagg
      721 atagcgagtt tttgactacc tacctctacg ctattgagtc ttggacctgg tttgaactct
      781 atcttttttg caatactatg cccttcttga gcaatcaaga tctgatcttt ttatcaacct
      841 ccttactcga aaaatccaag gaatttaaag agttagtaca caatcgatgg tatatgaaaa
      901 gtggttatct taatatcatc tcagaactta tggagcgcaa gctattttct tatgttccaa
      961 tctttgaagc tgagctggag cgcatgctcc gtccatacga tgtttttgaa aaagtattgt
     1021 ggcagttttt aaagaaaatg cagatttttc ttcaaaccaa aggaagcaat caaaaagaga
     1081 ttgaacactt tatccaatct ctgcaagtat tagaaaatcc acaattgaca gccctttttg
     1141 aattgcgttt gcagcaatac aaagagctta tcgattagtt agaaatggga aaaagataat
     1201 aatatcagca acgatcgtca ataatgttaa aacttgtttc ttcatattac ttccctcctc
     1261 attagtaata actttattat accagggaaa taatcaaatc taccaaaatc gcaaatctga
     1321 aatttctata agaaaaaaaa tcaaatatgc gattttctaa aataagccaa tttccgtgtt
     1381 atactgtcct tgtaaaacat ttgaagcaaa tcctaggtcg cagaagtggt ttacaaaaaa
     1441 ataatcaaag gagaaaagaa atgcataatc taatggaact tgaattgtta cctgaagagc
     1501 cagtaattac tgtatcacgg gaagtttgta agtggacttg ctcatttact gctctttaag
     1561 aataactggt taaaattaag gatagttgat tactaattaa ctatccttaa tttcatttca
     1621 gagataatgt atttattata tttatggata gattac
//
LOCUS       DAVMCN010000118         1623 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVMCN010000118 DAVMCN010000000
VERSION     DAVMCN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.119"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..186)
                     /locus_tag="VYP85_002064"
     CDS             complement(<1..186)
                     /locus_tag="VYP85_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882496.1"
                     /translation="MSNVDKIRKIHIIVCWGYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLA"
     gene            complement(183..536)
                     /locus_tag="VYP85_002065"
     CDS             complement(183..536)
                     /locus_tag="VYP85_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1882497.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            complement(592..1494)
                     /locus_tag="VYP85_002066"
     CDS             complement(592..1494)
                     /locus_tag="VYP85_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882498.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
BASE COUNT          581 a          290 c          214 g          538 t
ORIGIN      
        1 ggctagacag atagatacta ttttattttt cacagaatat agaggtagtg atactattga
       61 gtagataaaa gctaaaaaaa taagcaaaaa atactccgta tcatttataa tcgccctgaa
      121 tgataaaaat atataccccc aacacacgat gatgtgtatt tttcgaatct tatctacatt
      181 actcatctta ctgttgcaga tatgaatcca tcccaaggat aagggttccc gttaatatca
      241 caacctctat taagaacacc atatccaata cagtaagcta ttttccctgc tgctgtagcc
      301 aatacacctg ctgctgcacc aataagccag cctccaagac ctccaacctt aatatagttt
      361 attagttttt tggttaaaac tgcagctcca gctaatgcta taaaagttcc tgaactcata
      421 gctaaagctg cgcaaattcc ttgacaagca cgcttgctta aataagctcc cccatcaaga
      481 tacatcatta cttcttcatc aatcacaaca taattatttg gtaatacaag ttccatttgt
      541 tttctcctcc ttagttgaaa ttgtttcatt tgttttacaa ataggacgaa cttaaactat
      601 ctttttatta ctcagtaata atttccgaga tttcatttta tgatactctc tattcataca
      661 gaaatcaaaa ttttgcctta accaacttgt ataatagaaa aaatctaatt gatttattct
      721 gatgagctgt attctaattt tatcaacctt ttcttgccag ttgttattgt tactaataga
      781 aatctcatac agcagtaact cgacaagacc tgtacacaga agggtgttat gagaatcttc
      841 gatttttttc aaaatatcct caaaaagttc actatccgtt aaaaaggtgg attggttcat
      901 cgcatcatag agaagaaggg acattaagtc agaatagctt aattctgatt tttgtatttt
      961 gtccatcaat atcttatgca aattactttc aaatgaatct tctttttgcc atttgttttg
     1021 attaaaaaga aattccgtct tattaaaaac gagatgattg atatccatta tagtccagaa
     1081 aaatattgta gtaagcatga tgattgcaaa aggaattttt aaaataaata ctaggataat
     1141 agcaatttca agaataaaac tccatataat cctagatctt aaatcatcag gcgacaaact
     1201 tttacgatgg aatgaaaaat agggcgagaa tctcacattc acttttttcc ttcttataaa
     1261 aataaaggga aaaatcttaa taagaccttc tttcttgtat aaatctttca atgcgtatag
     1321 tatgtctaaa actatttttg ataaaatcaa actacagaaa gcaagactca tactaatcac
     1381 aaaatcaagg ggagattcta gattcaatag taagttattc actaggacat gcaactctag
     1441 ccacaagaca aaaagaggga gcattagtaa gaaaacaatt agtttacgta tcataatttt
     1501 acagtgtcct tatcattttc ttaattttgg ataaatcatc attgctatga ttaaaatcaa
     1561 aaaaacgaca ttaatccaaa taatcaactt ttttatttct tcgctaacaa aatcataggc
     1621 taa
//
LOCUS       DAVMCN010000119         1510 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVMCN010000119 DAVMCN010000000
VERSION     DAVMCN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.120"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            24..1370
                     /gene="gdhA"
                     /locus_tag="VYP85_002067"
     CDS             24..1370
                     /gene="gdhA"
                     /locus_tag="VYP85_002067"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1882499.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          465 a          295 c          321 g          429 t
ORIGIN      
        1 tatgacaata aaaggagaac gatatgacat ctgctaaaga atatatccaa agcgtgtttg
       61 aaactgtgaa agctcgtaac gggcacgagg ctgaattcct ccaagctgtt gaagaatttt
      121 tcaacacttt agaacctgta tttgaaaaac accctgagta tatcgaagaa aatatcttgg
      181 cacgtattac tgagcctgag cgcgtggttt ctttccgtgt tccttgggtt gaccgtgatg
      241 gaaaaattca agtaaaccgt ggttaccgtg ttcaattcaa ctcagctgtt ggaccataca
      301 aaggtggact tcgtttccac ccaactgtaa accaagggat cttgaaattc ctcggatttg
      361 aacaaatctt taaaaatgtc ttgactggac ttcctatcgg tggaggtaaa ggtggatcag
      421 acttcgatcc taaaggtaaa acagatgctg aagtgatgcg cttctgccaa agcttcatga
      481 ctgaattgca aaaacacatc ggaccatcac ttgacgtacc tgctggtgat atcggtgttg
      541 gtggacgtga aattggttac ctttacggtc aatacaaacg tcttaaccaa tttgatgctg
      601 gtgtcttgac tggtaaacct cttggatttg gtggtagctt gattcgtcca gaagcaactg
      661 gttacggttt ggtttactat actgaagaaa tgctcaaagc taacggtaac agctttgctg
      721 gtaagaaagt cgttatttca ggttctggta acgttgctca atatgctctt caaaaagcaa
      781 ctgaactcgg tgcaactgtt atttctgttt ctgactcaaa tggttatgtc atcgatgaaa
      841 atggtatcga cttcgatctt ttggttgatg ttaaagaaaa acgtcgtgct cgtttgactg
      901 agtatgcagc tgaaaaagca actgcaacct accacgaagg tactgtatgg acttacgctg
      961 gaaactatga cattgctctt ccatgtgcca ctcaaaacga aatcaacggt gaagcagcta
     1021 aacgtttggt tgctcaaggc gttatctgtg tatctgaagg tgccaacatg ccgagcgacc
     1081 ttgatgccat caaagtttac aaagaaaatg gtatcttcta cggacctgca aaagctgcca
     1141 acgctggtgg tgtagccgtt tcagctcttg aaatgagcca aaacagtctt cgcctctcat
     1201 ggactcgtga agaagttgat ggccgtctca aagacatcat gacaaacatc ttcaacacag
     1261 ctaaaacgac ttcagaaaca tacggtcttg ataaagacta ccttgcagga gctaacattg
     1321 ctgcctttga aaatgtagca aatgccatga ttgcacaagg tattgtttaa gatttattta
     1381 ctcaatcctc aatcactacg attggggatt tttagcttga attaaaaaat tggaaaatct
     1441 aattaaataa aatgaaatga aataaaaact gaacaaattg attgcggaat tcaaaccaat
     1501 ttctaacata
//
LOCUS       DAVMCN010000120         1469 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVMCN010000120 DAVMCN010000000
VERSION     DAVMCN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1469
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.121"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            22..816
                     /locus_tag="VYP85_002068"
     CDS             22..816
                     /locus_tag="VYP85_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882500.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            820..1017
                     /locus_tag="VYP85_002069"
     CDS             820..1017
                     /locus_tag="VYP85_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882501.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            1007..1469
                     /locus_tag="VYP85_002070"
                     /pseudo
     CDS             1007..1469
                     /locus_tag="VYP85_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          496 a          208 c          282 g          483 t
ORIGIN      
        1 atgatagaat aaggaaaaaa catgaatgtc aaaaagataa tgtcaatttt tcaatccttt
       61 tatgttgatg tcagtattga ggaactgact ttgactttac caatcagttt tgtaaaaagg
      121 tttgagtata ctcaaatgac ttttcataag gaatcatttt tattgattaa agaaaagaga
      181 agggggagtt tgagttcatt tgttactcag gctcgcacta tgggtgaaaa agccaatatg
      241 gatgttgttt tggtgttttc gaagttatca gacagtgaaa aaaagcaatt acttcaagct
      301 agagttccgt ttgtagactt taagggaaac ctcttcttcc ctccattggg actagtactc
      361 aatgcgaatg atactgaagt ccctaaggaa ttaacaccta gcgaacaatt aacgtggatt
      421 gcctttttat tgacaaaagg tcaaaaagta gtagatgttg atttgctttc acaagtcact
      481 ggacttccaa actcaacaat ttataggtgt ttgaggactt ttaaagcttt atattggtta
      541 aacaagcaaa ataagcttta cacatatacg gtgtcaaaga aagaattatt cttaaaatcc
      601 gtgtcatgtt tatttaatcc catcaaaaaa cggattttat tgccagatgg cgatataaag
      661 cagataaaat ctgtttctaa ccttctatat ggtggtgctt atgctttgtc gcattcaact
      721 tttttagctg aaacggatga aaatattagc tatgtcatat ggcagagaaa attcaatcag
      781 ttatccttgc cactttctca gcatgtttta aaatgaaaga tgctagagat atggaaatat
      841 cgtccttttg tatctgagtt ttggaatgat tttaaaaata atcatgataa acaatttgta
      901 gatccgattt ctctttattt gaccttaaaa gatgatgatg acccacgtat agaggaagag
      961 agtgaagcac tagaaaatat gatattacag tatctgggag aagatgatgc cagctaatac
     1021 gaaagttatt tttcaagaaa tgtttgcgga ttttcagaac tattatgttc tgattggggg
     1081 aactgctacc tctatcgtat tggattcgca aggatttaaa agtcgcacaa caaaagatta
     1141 tgatatggtc atcattgatg aagtaaaaaa taaggaattt tatactacct tgaatcattt
     1201 tttagaattg ggagagtatc aaggaagtca gaaagatgag aaagcgtagc tttttcgatt
     1261 tacaacaact aatcctgagt ttccttctat gattgaacta tttagtatct taccagaata
     1321 tccattaaag aaggacggtc gagaaattcc cttacatttt gaccaagatg ctagtttatc
     1381 agccttatta ttggatgaag attattataa tatattggtg catgaaaaag aaaccattca
     1441 ggggtattcg gtattgagta attgtggtc
//
LOCUS       DAVMCN010000121         1455 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVMCN010000121 DAVMCN010000000
VERSION     DAVMCN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.122"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..559
                     /locus_tag="VYP85_002071"
     CDS             <1..559
                     /locus_tag="VYP85_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1882502.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNISIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VYP85_002072"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VYP85_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1882503.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          508 a          206 c          263 g          478 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt tctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgat tacaaggagt aaataaatat ctgactttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaacca tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtagtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DAVMCN010000122         1438 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVMCN010000122 DAVMCN010000000
VERSION     DAVMCN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.123"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            122..913
                     /locus_tag="VYP85_002073"
     CDS             122..913
                     /locus_tag="VYP85_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882504.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLANLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            929..>1438
                     /locus_tag="VYP85_002074"
     CDS             929..>1438
                     /locus_tag="VYP85_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882505.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGIL"
BASE COUNT          503 a          172 c          255 g          508 t
ORIGIN      
        1 aggcgcaact ttttaaactc aataagaatc aaagagcaaa ccgagaatat taatggagga
       61 ataaaaaatg taagttataa atgtaagtaa gcattatggt cattcaatca ttctcaaaga
      121 tataaatttt gcacttaaca agggtgaaat tgttggtcta gtagggagaa acggagttgg
      181 taagagtaca ttgatgaaaa ttcttgttca gaataatcaa ccgacttcag ggaatattat
      241 aagtagtgat aatgttgggt atttaattga agaaccaaaa ttatttttat ctaaaacagg
      301 tttagagaat ttaaaatatc tggcaaactt atatggtgtt gactacaatc aagaaagatt
      361 tagaagtttg atccaagagt tagatttgac tcagtctatt aataaaaaag taaagaccta
      421 ttctttgggt acaaaacaaa aattagcttt gcttctaact ctcgttacga aacctgatat
      481 attgatttta gatgaaccga ctaatggttt agatattgaa tcatcacaaa tagttttagc
      541 ggttctaaaa aaattagctt taaatgaaaa cgtgggaatt ttaatatcga gtcataaatt
      601 agaagacatt gaagaaattt gtgagagagt tcttttcttg gagaacgggc ttttgacatt
      661 tcaaaaagta ggaaaagata gtcataattt cttgtttgag atagcttttt catcagctac
      721 agatagagac attttcatta ccaaacaaga atttggggat attgttcagg aagagggatt
      781 gagaattact atgtctggga atattcaaag tagtgagctt tttaaatttt ttaacgaaaa
      841 ctctattaaa gtagttgatt ttgaaactaa aaaagagacg cttaaagata tttacctaaa
      901 tcgttcaaaa taaaggaagg ttataatcat gaaattaaat aaattgaatt ttcttaagga
      961 aaatataaga aatttatatt catcaggcgt aatatatctc ggtttgctta tctcgtttat
     1021 accgccgata ttgcttacat tctttattct aaagactcaa gggacatcgc ttggtattaa
     1081 gcatatttca aacttttatg ctatgctcgg tatgttaatg gctgttatac atgctaatcg
     1141 agtcattagt agagattttt cccacaatac ggtaagtttg ttttataatc aacagaagaa
     1201 tcggatgatt tacgtcttgt ctaattttct atatgccatc tcagtttcca ttatttatgc
     1261 tttgaatggc attgtgttac tagtcatagt aagtaaattg ggtattccag gtgatttagg
     1321 attagatttt atagtagcta ttgtagtcaa tacaattttg ttagtcctgt tttattttct
     1381 attatcttac attttctatt tatacaaatt gaaaagtggc ttggtatttg gtatttta
//
LOCUS       DAVMCN010000123         1352 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVMCN010000123 DAVMCN010000000
VERSION     DAVMCN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.124"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            338..>1352
                     /locus_tag="VYP85_002075"
     CDS             338..>1352
                     /locus_tag="VYP85_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV1882506.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEK"
BASE COUNT          629 a          180 c          228 g          315 t
ORIGIN      
        1 aaaatcatct aaagatgaaa taacataatt gtcccttggt tacaagggcg caattataca
       61 ccctaaaggg tgcttgcgtc ctgcggagtc aaacccttgc agggagtaac aaccattcgc
      121 tttttaaaag tcaagggtaa ataaactcgc taaggctcgc ccttgacttt taaaatttga
      181 aatgaaagta acaattaagc cgacatactg aaacaacaaa aattaattca gtagtcggct
      241 tttttaattc tatcatttca aaacgctcat tcacaaagag gatataaaaa aactattaag
      301 cctccaccta aaacaacaaa gaaaggaagt gataaaaatg gcagacagtt ttcatttttc
      361 agtaaacata atatcaagag gaaaaggcaa aagtgcagta gcaagtgcag catatataag
      421 tggagaaaaa ataaaaaatg aatgggacgg agtaacccat gactatacaa gaaaagaaaa
      481 aatattagta aaaaatataa tattgcctga tcatatacca aaagaattta atgataggtc
      541 taccttatgg aataaagtag aaatggcaga aaaaaattct aatgcacaac tagcaagaca
      601 attcataata ggactaccaa aagagttatc tttaagtgaa aataaaaacc tggttgaaag
      661 atatataaaa gaaaatttaa catcacaagg aatgatagta gattatgcaa ttcatgatga
      721 gagtcaagat aaaaatggaa atatccattg tcatataatg accataatgc gaccaataaa
      781 cgaaaaagga gagttcttag ccaagtcaaa aaaagaatat atcctagatg aaaaaggaga
      841 aaaagtatta aacaaaaatg gaaaaccaaa gacaagaaaa gtagaactaa caacctggaa
      901 cgatacaggc aatgtagaaa aatggagaga aaatttttca gatctttgta acaaatattt
      961 agaaagagca ggagcagaaa aaagagtaga ccataggagt tttaaaagac aaaattcaga
     1021 ttatctaccg acaatccatt taggatcagc agcaagtgca atggaaagaa agggaataga
     1081 aactgacaag ggaaactata atagagaaat aagaaaatat aatcaacttg taaaaacaat
     1141 aaaagaagag ataaaaacat taaagggttg gataggaaat ttattagata acttatctac
     1201 tgcttatgaa aaatttaagg atatagaaag agataaggta atagacaacc ctaaactttt
     1261 taatctaaca aattatctat taacttattc agaaattcaa aaagaaaaaa gtaaatatct
     1321 aaaaggatat gcaaaaacta ataaagaaaa at
//
LOCUS       DAVMCN010000124         1335 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVMCN010000124 DAVMCN010000000
VERSION     DAVMCN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.125"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            369..749
                     /locus_tag="VYP85_002076"
     CDS             369..749
                     /locus_tag="VYP85_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1882507.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSADAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGVDWADGSLDGYIFA"
     gene            complement(1150..>1335)
                     /locus_tag="VYP85_002077"
     CDS             complement(1150..>1335)
                     /locus_tag="VYP85_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1882508.1"
                     /translation="EDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSM
                     LSHLKKEVETHYQPKKL"
BASE COUNT          413 a          167 c          280 g          475 t
ORIGIN      
        1 aatgtaaggg agcttgagtt gttagtggag gataaaatgt taagagtaat agtagttatt
       61 caatctttag taataatact gcttgctgtt gctttattat tatctcggaa aaactttgat
      121 tcgttaaatg ttgttcttat aatgatgatc gtatcacaat tgttgttatt agtatatttg
      181 ataaaatcag ggaatcagtg attagctgtt atttgaatta agtaaactgt taagcttcaa
      241 gcagtaactg gttttaaata tttaaaataa gataaaggaa ggaagtctaa tttaggtaac
      301 taaacaaagc ctgcgatcac ttgttaggaa accatcctaa ccatgcttaa taaaaaagga
      361 gaaaataaat ggaactcgta ttaccaaata attatgttgc tcttgagcaa gaagagatga
      421 tgtatcttga tgggggtggt gttggtcgta actggtggaa tagtagaggt agttttgcaa
      481 cagttctgga tgtagatttg gccatctata gtggtggtgc aacaatttat tctgctgatg
      541 cgataaaaaa agctatctca gctaatagag gggctattac gagaacatta cgtagtttaa
      601 taattaaaca tgtaggtagt gcagctggcc atttagtcaa tactgcacta aacgttgcac
      661 taactgttac tggattttca ctaggtggag caatcgcata tggggttgat tgggctgacg
      721 gtagcttaga tggttatatt tttgcttaaa atgaaacatt tttttgcagg aattggtgaa
      781 ataaactttg taagttattt attgtatata tgtgtaggaa tagccccttt ttttcacgta
      841 tatataatag gttctgaaat gaattttgtg aaaatagtgt tatctatttt gggaattata
      901 tttgtttgta ttttaactat tgctcgaatt tataggactt ttttctataa agaatagttt
      961 ggacttgaaa tgtatttaaa aacaagaggt tggtagatta tcagcctctt tcttgtcgtt
     1021 gaaaaagtga gatatattga cttttgaaaa aaatgtcata attgagttgg gataaacgta
     1081 aaagtcatac tttctcgtta aatcgttcgg cgattctatg aaaaggtcga ggagctccct
     1141 cgactttttt tataatttct ttggttgata atgggtctct acttcttttt tgagatgaga
     1201 cagcatagaa gtttcctcgg tcagctctag gagtgagaaa cctttttgga taagtttagc
     1261 attatctgta caaatcccaa tacggacata gcagatagca agcctatcgt agcttttctt
     1321 attcttggcg tcctc
//
LOCUS       DAVMCN010000125         1162 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVMCN010000125 DAVMCN010000000
VERSION     DAVMCN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.126"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..327
                     /locus_tag="VYP85_002078"
     CDS             <1..327
                     /locus_tag="VYP85_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1882509.1"
                     /translation="KLLQKMHYFVLPSYYKDETLPISMLEAMANGLYIIVSDVGVVSE
                     VINKETASLIEMINEETADSIIEIINQTSNKLNELDFNVSKYKQELLNENIQASIYQQ
                     LERIAN"
     gene            324..>1162
                     /locus_tag="VYP85_002079"
     CDS             324..>1162
                     /locus_tag="VYP85_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1882510.1"
                     /translation="MTKKKNTGKILTVVVPSYNAENYLQETMPTILSAKNIERVELLI
                     VNDGSTDRTEEIARQFEREYEGIVRVISKENCGHGSAVNVGIENAVGNYFKVVDADDW
                     VNTNNLEDLIVFLSEVDVDQVLSPYDKIFVNYRGDIEREEECNEFSQVENEVIYSAEE
                     FYTRIKQTVGMHSITVKTSLLQENNIRLSEKMFYVDMEYIVYMLPYVKKVVLFDKSIY
                     RYRLGTETQSISMASYIKNRDMHKQVIYHLVDFYNQMRSSAVLRRITWKLILNLIRQQ
                     WII"
BASE COUNT          439 a          128 c          243 g          352 t
ORIGIN      
        1 aagttattgc aaaaaatgca ttactttgtt ttaccatcgt attataaaga tgaaacttta
       61 cctatcagta tgttagaagc aatggcaaat ggtctctata ttattgtaag cgatgtggga
      121 gttgtgtcag aggtgattaa taaagaaact gctagtctta ttgaaatgat aaacgaagaa
      181 acagcagaca gtatcataga aattattaat cagacttcaa ataaacttaa tgagttagat
      241 tttaatgtat caaaatataa gcaagagttg ttaaatgaaa atatacaagc atcaatttat
      301 cagcaattag agaggatagc aaattgacga agaaaaaaaa tactggaaaa atattaacag
      361 tagttgtacc atcatataat gcagaaaatt atttacaaga gacgatgccg acgatacttt
      421 ctgctaagaa tatagagagg gtagaattac tgattgtaaa cgatggttct acagacagaa
      481 ccgaagaaat agcaagacaa ttcgagagag aatatgaggg aattgttaga gttataagta
      541 aggaaaactg tggtcacggt tcggcagtaa atgtggggat tgagaatgct gttggtaatt
      601 actttaaagt ggtagatgca gatgattggg tgaacaccaa taatttagaa gatttgatag
      661 tgtttctatc tgaggtggat gtggatcaag ttttatcacc atatgataaa atttttgtga
      721 attatcgagg tgatatagag cgtgaagaag agtgcaacga gttttcgcaa gttgagaacg
      781 aggtgatcta ttctgcagaa gaattctata cacgaattaa acaaacggta ggaatgcatt
      841 ccattactgt gaaaacgagt cttttgcaag agaacaatat tcggctgtct gaaaaaatgt
      901 tctatgtaga tatggaatat attgtttata tgcttccata tgtaaaaaag gttgttttat
      961 ttgataaaag tatctataga tatcgtctag gaacagagac acaaagcatt agtatggcga
     1021 gttatattaa aaatcgtgat atgcataaac aagtgatcta tcatttggtt gatttttata
     1081 atcaaatgag atctagcgct gttttaagga gaataacatg gaaattgatt ttaaatttaa
     1141 taagacagca atggataatt ta
//
LOCUS       DAVMCN010000126         1154 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVMCN010000126 DAVMCN010000000
VERSION     DAVMCN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.127"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..991)
                     /locus_tag="VYP85_002080"
     CDS             complement(<1..991)
                     /locus_tag="VYP85_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1882511.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEA"
     gene            complement(1001..>1154)
                     /locus_tag="VYP85_002081"
     CDS             complement(1001..>1154)
                     /locus_tag="VYP85_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1882512.1"
                     /translation="GDKCKALKVIKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYV
                     QLKFRK"
BASE COUNT          413 a          198 c          143 g          400 t
ORIGIN      
        1 ttgcttcata taacggaaaa tctctattca cctcatttgg ttcgatatca ttcattttat
       61 ttgactcaat tggattaatt gaatacaatt ttaaaaaaat aggcttcgta ccaataatag
      121 aggataattg acctcctaat tcacctagcg ctgtaaaaat aacacctgtt agtgctccta
      181 ttgcttcaat agtaccaatt ttcactattc cttttattgc aagatagcct gttaaaaaaa
      241 cgagagatat ctgaaaaaaa atattgagaa agaagctaat agcacctgct aacgtttcta
      301 cagttgtctt tctttgtata accatcttta ataaaattcc tgcttcttta attttcttag
      361 gcaatacata taaaagattc aaggacgcta acacatcaaa tccattcaat atagtctcac
      421 tagattttaa aaaagcttca ttttggttag ttaaatttag actaacttct cgcattttcg
      481 atgcaaagat ttttggtaca agtagcataa tcattaatga aaacaaggtg gctacagtca
      541 atgaccaatg atagtgatta agagtcacaa ctgcaaatat agtaccagaa attcctttta
      601 ttactaaaaa aagttgttta aaagcctgat catttaaagt ctgaacatca ttatttagcc
      661 acgaaagata tgttcctgat gatttactat gaaattcttg ataggtagag ttagagatgt
      721 ctgtggcaac tctatttcga atctctagat taaactcttg gatcacttca acctgataat
      781 ttttcactac ccagtcaagg aatattatcc cacaccagac aatcatttgg tagattgaca
      841 atttcaaaaa ccgctctaaa ttcatcgcaa ttaattcatt caacaccaga gcattaatag
      901 ttgctgcata aattagcaat aattgaccag caacaataaa tatcgttaat aaactaaatt
      961 tttttatatt tgattttata atagtataca caatagtttc tcactttcta aattttaatt
     1021 gaacatagtt gtcatatata caatagaaaa aaccaaaatg atataataac atatatttca
     1081 aaaaaagaaa ttcgttaaaa attttttctt ctcttgcctt cttgattact tttaaagcct
     1141 tgcatttgtc tcct
//
LOCUS       DAVMCN010000127         1137 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVMCN010000127 DAVMCN010000000
VERSION     DAVMCN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.128"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            21..743
                     /locus_tag="VYP85_002082"
     CDS             21..743
                     /locus_tag="VYP85_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1882513.1"
                     /translation="MQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISI
                     VSQGDDNSYYGNKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(691..>1137)
                     /locus_tag="VYP85_002083"
     CDS             complement(691..>1137)
                     /locus_tag="VYP85_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1882514.1"
                     /translation="IIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVST
                     SLEHIGKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITK
                     LSGQALYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
BASE COUNT          421 a          176 c          177 g          363 t
ORIGIN      
        1 aatctattct tcaatatgct atgcaaggaa aattagttga acaagaccca aatgatgaat
       61 cagtcgaagt tttacttgaa aaaatacgag cagaaaaaca aaaactcttt gaagaaggca
      121 agattaaaaa gaaagatttg gacatttcta ttgtttccca aggagatgat aactcttatt
      181 atgggaacaa agacgaaaca acctcttatc ctatatatga aatcccagaa gcatggagat
      241 atattaaatt tgctagccta gttaacttca gaataggaaa aactcctcca cgcagtgaag
      301 ctactttttg gggaactgaa ataccctggg tatctatatc agatatgcct atatctggtt
      361 atgtaactaa tacgagagaa tctatttcta aattagcatt aaaatcaaag aaaatagaca
      421 tttcacctaa aggaacttta ttaatgagct ttaaattatc tattggaaaa gttgccatat
      481 tggatattcc tgccactcat aatgaagcca ttatatcgat attcccctat gctaataaag
      541 aaaatattat cagagattac ttaatgatat ttttgccact tatctctact ttaggtgatt
      601 caaaagatgc tatcaaaggg aaaacattaa atagtaccag tatctccgaa ttattaatcc
      661 ctatttctaa tcatgaagag atgaaaagaa tcatttccaa agttgattta ctttttcaaa
      721 aagtttctca actttttgag taataagttc ctgttcctca aaaggagcta acggaattaa
      781 tagctcgctt agtgtagttt taggaatatt atataaagct tgacctgata gtttagttat
      841 tgctttcaat tgtttataaa ataacggaga ggacaagtta aataatagaa attttgaaat
      901 aatctctgaa ctttcgaatg gtgttaattg gaaaataaat ccaccagcca caacaccatc
      961 atagtcttta tcgattcttg caaactttcc aatatgttct aaagaggttg atacaggtgt
     1021 tattagctga ttatgtttta aataaacttg ctcagaggag atgaattgtg tatcaatgta
     1081 gtaatcatta tccaacagag aaaattctaa aggcttaata ttaccaccac gtataat
//
LOCUS       DAVMCN010000128         1075 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVMCN010000128 DAVMCN010000000
VERSION     DAVMCN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.129"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            68..>1075
                     /gene="pcpA"
                     /locus_tag="VYP85_002084"
     CDS             68..>1075
                     /gene="pcpA"
                     /locus_tag="VYP85_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1882515.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AF"
BASE COUNT          417 a          154 c          175 g          329 t
ORIGIN      
        1 ttataacaac ggctagcaaa gttataattt tatatctatt agaaaataaa tatgtaagga
       61 aatttaaatg aaaaaaacta caatattatc attaactaca gctgcggtta ttttagcagc
      121 atatgtccct aatgaaccaa tcctagcaga tactcctagt tcggaagtaa tcaaagagac
      181 taaagttgga agtattattc aacaaaataa tatcaaatat aaggttctaa ctgtagaagg
      241 taacatagga actgttcaag tgggtaatgg agttactcct gtagagtttg aagctggtca
      301 agatggaaaa ccattcacga ttcctacaaa aatcacagta ggtgataaag tatttaccgt
      361 tactgaagta gctagtcaag cttttagtta ttatccagat gaaacaggta gaattgtcta
      421 ctatcctagc tctattacta tcccatcaag cataaaaaaa atacaaaaaa aaggcttcca
      481 tggaagtaaa gctaaaacta ttatttttga caaaggcagt cagctggaga aaattgaaga
      541 tagagctttt gatttttctg aattagaaga gattgaattg cctgcatctc tagaatatat
      601 tggaacaagt gcattttctt ttagtcaaaa attgaaaaag ctaacctttt cctcaagttc
      661 aaaattagaa ttaatatcac atgaggcttt tgctaattta tcaaatttag agaaactaac
      721 attaccaaaa tcggttaaaa cattaggaag taatctattt agactcacta ctagcttaaa
      781 acatgttgat gttgaagaag gaaatgaatc gtttgcctca gttgatggtg ttttgttttc
      841 aaaagataaa acccaattaa tttattatcc aagtcaaaaa aatgacgaaa gttataaaac
      901 gcctaaggag acaaaagaac ttgcatcata ttcgtttaat aaaaattctt acttgaaaaa
      961 actcgaattg aatgaaggtt tagaaaaaat cggtactttt gcatttgcag atgcgattaa
     1021 acttgaagaa attagcttac caaatagttt agaaactatt gaacgtttag ccttt
//
LOCUS       DAVMCN010000129         1064 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVMCN010000129 DAVMCN010000000
VERSION     DAVMCN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.130"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..1064
                     /locus_tag="VYP85_002085"
                     /pseudo
     CDS             1..1064
                     /locus_tag="VYP85_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          325 a          240 c          180 g          319 t
ORIGIN      
        1 tcaaatgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
       61 tatgccttct agaattctcc ttagaaaacg ccgtttcaag tgctatcact gttcaaaaat
      121 gatggttgct gagactcccc tggtaaagaa aaatcaccaa atccctcgta tcatcaacca
      181 aaaaattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc atcagctttc
      241 catctcaact tcaactgtca ttcgcaagct caatgattct cactttgagc atgatttttc
      301 gcgtcttcct gagattatgt cctgggacgt tgaaacagtc cggggagtga ctgtttcaat
      361 cgggagatgg agatgagctt cattgcgcaa gattttaaca atctcaatat catcactgtt
      421 cttgagggaa gaacacaagc tatcattcga aatcactttc ttcgctacga tagagctgtc
      481 cgatgtcgcg tcaaaattat tactatggat atgtttagcc cttactatga cttggctaaa
      541 cagcttcgct ttcaaatttc taggctcagg ctgaaacagt ctcccagact gtttcactcc
      601 cgaatgctaa aatcgttctt gatcgctttc acattgtgca acatcttagc cgtgctatga
      661 gtcgtgtgcg tgttcaaatc atgaatcagt ttcatcgaaa atcccatgaa tacaaggcta
      721 tcaagcgcta ctggaagccc atacaacagg atagccgtaa actgagtgat aagcgatttt
      781 atcgtcctac ttttcgtatg catttaacca ataaagagat tttagacaag cttttgagct
      841 attcacaaga cttgaaacac cactatcagc tctatcagct cttgctgttt cacttccaga
      901 ataaggaacc agagaaattt ttcggactta ttgaggacaa tcttaagcag gctcatccta
      961 tttttcagac tgtctttaaa accttcctca aagataaaga aaagattatc aacgcccttc
     1021 aactacacta ttctaatgcc aaactggaag cgaccaataa tctc
//
LOCUS       DAVMCN010000130         1032 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVMCN010000130 DAVMCN010000000
VERSION     DAVMCN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.131"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..574
                     /locus_tag="VYP85_002086"
     CDS             <1..574
                     /locus_tag="VYP85_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1882516.1"
                     /translation="KIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIVAHRLSTIKDADVIFV
                     MKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            587..757
                     /locus_tag="VYP85_002087"
     CDS             587..757
                     /locus_tag="VYP85_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882517.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          375 a          127 c          198 g          332 t
ORIGIN      
        1 aaaaatacca tcaagattat ataagattga tacaggaaaa gttttatttg atggtgtaaa
       61 tattaatcaa atagataaaa aaatattaag tcaaaattta ggagtagttc cacaggattc
      121 atttttattg aaccgaagta ttcttgataa tataacttta aagcacgaag ttacttcaca
      181 aaagatagag gaagtttgta aagcagttca aatctatgat gaaatcatgg ctatgccgat
      241 gaaatttaat actatcatct cagagatggg gtcaaatatt tcaggtgggc aaaggcaacg
      301 gatagcactg gcacgtgcat taataaataa tcctagtatt gtaattttag atgaagcaac
      361 tagtgcatta gacactatta atgaggaaag aataacaaag tatatacaaa gtcagggctg
      421 tactcaaata attgtagctc atagattgtc aacgattaag gatgcggatg ttatttttgt
      481 aatgaaaggt ggtaagattg ttgagtcagg aaatcataag tacttaatgg atcttggtgg
      541 agagtactac agcttatata caaaaaggaa atgaggtgta aagaaaatga agaaagaaaa
      601 tgaatatgta attttaacaa cagcctcact aggggtgatg attggaatag tgtttgcaat
      661 ttttttagat tttccagttg aatatggtat ttctttaggc ttgttgaatg gaatagtatt
      721 gggttcgctg attgtttaca aaaacaataa gaattaagca taattttttg ctgtaaacta
      781 aggagtagag atggctatag ttgaaattat aaatctaaca aaaagcttta aagatattga
      841 agttattcat aacacttaaa taatagagca actacagtag tagcttaaaa acatgattaa
      901 atcgctattc ttaggagtag cggtttttct ttttgtttaa tactctttga aaatctcttc
      961 aaaccacgtc agctttgctt taccgtactc aagtacagcc tgcggctcgc ttcctagttt
     1021 gctctttgat tt
//
LOCUS       DAVMCN010000131          987 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVMCN010000131 DAVMCN010000000
VERSION     DAVMCN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.132"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(763..>987)
                     /locus_tag="VYP85_002088"
     CDS             complement(763..>987)
                     /locus_tag="VYP85_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882518.1"
                     /translation="TTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKA
                     GYLFSVLLLFSNFSVPFIKEKEFELFKNSK"
BASE COUNT          371 a          182 c          120 g          314 t
ORIGIN      
        1 tatctcactc ttttcaacga caagaaagag gctgataatc gaccaacctc tgtttttaga
       61 tacagttcaa gtccaaacta ttctttatag aaaaaagtcc tataaattcg agcaatagtt
      121 aacatactta caaatataac tcccaaaata gataacacta ttttcacaaa actcagttcc
      181 gaacctatga catatatatg aaaaagaggg gctagtccta cacatatata caataagtag
      241 ccaacaagtt ttatctcacc aattcctgca aaaaaatgtt tcatgtaacg attctccatt
      301 tactccatta aatcagtttt attttagact atcataaaac aatcacctct tcaataaaaa
      361 ccattggcga aatactattc tgaagcattg atagctcaga tttctcagaa taaagctgtc
      421 ctaactatcg agcagctcaa atacatatat atgagcaatt ctaagcctag aattgctata
      481 aaataaatgt tttcgggcta ttctaagtct ttgactgctt aaaattttac attctgaagg
      541 attctaaacc tagaatagct caaaatcacg agaactaagg tattcgaaac ttcagagtaa
      601 tacaatcccc ataggaattc tccattctta ttaagcatga ttaaaatgta atcctaacaa
      661 gtgatcctcg actgtgtttg tagcacttag ttacctagat aagactattt ccctttatca
      721 tatctgattt taagccgttc taagatttaa cctatgtttc tattacttgc tatttttaaa
      781 taattcgaat tccttttctt tgataaatgg aactgaaaaa ttagaaaaaa gaagtaaaac
      841 cgaaaacaaa tagcctgctt tttgaatcac taaaagatat cctaaaaata agtaagctat
      901 aacatccaat gcgaaaagaa aaaatattct cctcttcatt aaagtacttg tgtcaaataa
      961 tctgatgaat aaaaatttta tcgtagt
//
LOCUS       DAVMCN010000132          968 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVMCN010000132 DAVMCN010000000
VERSION     DAVMCN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.133"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            268..606
                     /locus_tag="VYP85_002089"
     CDS             268..606
                     /locus_tag="VYP85_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1882519.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            703..>968
                     /locus_tag="VYP85_002090"
     CDS             703..>968
                     /locus_tag="VYP85_002090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882520.1"
                     /translation="MSPGTFIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLALIF
                     LIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVYIFLGYV"
BASE COUNT          310 a          121 c          218 g          319 t
ORIGIN      
        1 ttttgtattc tagtatgtat gatatcattg attagtctgg ccataatctt tccatggggc
       61 tggtcgatat aatgtaaggg agcttgagtt gttaaaggag gcttagtcct tggacaaaaa
      121 tctgctgtac tacaatgctt ggaaagatat caagaacaaa gaatgatacg attgaaacta
      181 aactgattca agaactactg ggcagtgatt gaggtttggg tgacatcaaa gaaaagttag
      241 attaattcta aagaattgag tatttctatg ttaaaaaaat atccttgtac gatgcaacat
      301 gatcagtcag attgtgctgc ggcagttgtt tcaacagttc ttttatctta caaaaaggaa
      361 ctatcaatca tgaagattcg ggaaattatt ggtacagaca tgtatggaac gactgtcagt
      421 ggtattgttt caggtctgaa taagttgaat tttacagtaa aagctgttcg agtagcactg
      481 gaagatttga ctccaaaatt aacatttcct gcgattcttc aagttaagaa tgatttaggt
      541 caaaatcatt ttgtggtatt acatagtata aaggagaaaa taaagggaac tcgtattacc
      601 aaataattat gttgctcttg agcaagagga gatgatgtat cttgatgggg gggggcttat
      661 ttaagcaaga gtgcttgtca aggaatttgc gcagctttag ctatgagtcc aggaactttt
      721 atagcattga ctggagctgc agttttaaca aaaaaactaa taaactatat taaggttgga
      781 ggccttggag gttggcttat tggtgcagca gcaggtgtat tggctcttat ctttttgata
      841 aaaatttgtg tagatactac gataaaggtt ctattaaaca gaatctttaa ggcaagtaag
      901 gtaatgaaaa ggaggatatt ttctcttttt gtactagatt tgatggtcta tatattttta
      961 ggttatgt
//
LOCUS       DAVMCN010000133          922 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVMCN010000133 DAVMCN010000000
VERSION     DAVMCN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.134"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>922
                     /locus_tag="VYP85_002091"
     CDS             <1..>922
                     /locus_tag="VYP85_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1882521.1"
                     /translation="TATIQNLSIKEANVSSKEDAATISKEAKYNTLIDNVHSDGIIAG
                     ERGIGGLVSKVDNSRISNSSFTGRITNTYDTTVGYEIGGLVGKLSGSLASIEKSIASI
                     DIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQD
                     VSKSGKLSYVLSDVNVTNGNAISGDNFDNMKEDHAYSSKGNKVVNVVQVDDELVTKDS
                     DVQRGTVLDADKVKEKKAELVSKHSTKVEDFDFTSRYTTIYNEVTGYQKSREQVYKNI
                     EKLLPFYNRETIVKYGNLVDESSELFTKELL"
BASE COUNT          345 a          110 c          195 g          272 t
ORIGIN      
        1 acaccgctac tattcagaat ctttcaataa aagaagcgaa tgtttcttct aaagaagatg
       61 ctgctacaat atcgaaagaa gcaaaataca atactcttat agataatgtt cattctgatg
      121 gtattatagc tggtgaacgt ggaattggtg gattggtttc aaaagtagat aactcgagaa
      181 tttctaatag tagttttaca ggcagaataa ctaacacata tgatacaact gtagggtatg
      241 aaattggtgg tttagtaggt aaactttctg gttcgcttgc ttctatagag aaatcaatag
      301 catcgattga catagcctct aatgcaaaat caggagatca aattgttggt ggtatagccg
      361 gagttgttga gaaaagtgcg acaattaagt atagctatgt tgaaggaaat gttaacaatg
      421 tgcgacactt tggtaaagtt gggggagttg caggtaatct ttgggataga gattcacaag
      481 atgtaagtaa atcaggtaaa ctatcatatg ttttaagtga tgttaatgta acaaatggta
      541 atgctatatc gggtgataat tttgataata tgaaagaaga tcatgcttat agtagtaaag
      601 gcaataaagt agtaaatgta gtccaagtag atgatgaact tgtgactaaa gattcagatg
      661 tacaaagagg tacggtatta gatgctgata aagtaaaaga gaaaaaggca gaattggttt
      721 ccaaacacag cactaaagta gaagattttg atttcacttc aagatacact actatttaca
      781 atgaagtaac aggttatcaa aagtcgagag aacaagtata taaaaatatt gaaaaactat
      841 taccgttcta taatcgagag acaattgtta aatatggtaa tttagtagat gaaagcagcg
      901 agctatttac taaagaactt ct
//
LOCUS       DAVMCN010000134          919 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVMCN010000134 DAVMCN010000000
VERSION     DAVMCN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.135"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            83..880
                     /locus_tag="VYP85_002092"
     CDS             83..880
                     /locus_tag="VYP85_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1882522.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFVLVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
BASE COUNT          241 a          158 c          201 g          319 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagttta ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggggttgta gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaaca ttgccattct
      601 ttcatttgtt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttca
//
LOCUS       DAVMCN010000135          899 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVMCN010000135 DAVMCN010000000
VERSION     DAVMCN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.136"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>899
                     /gene="phtD"
                     /locus_tag="VYP85_002093"
     CDS             <1..>899
                     /gene="phtD"
                     /locus_tag="VYP85_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1882523.1"
                     /translation="PEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRKVGD
                     GYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKA
                     YDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERL
                     GKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKD
                     SLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYN
                     LQYTVEVKNGSLIIPHYDHYHNI"
BASE COUNT          300 a          191 c          190 g          218 t
ORIGIN      
        1 ccagaacaac caagtccaca atcgactccg gaacctagtc caagtctgca acctgcacca
       61 aatcctcaac cagctccaag caatccaatt gatgagaaat tggtcaaaga agctgttcga
      121 aaagtaggcg atggttatgt ctttgaggag aatggagttt ctcgttatat cccagccaag
      181 gatctttcag cagaaacagc agcaggcatt gatagcaaac tggccaagca ggaaagttta
      241 tctcataagc taggagctaa gaaaactgac ctcccatcta gtgatcgaga attttacaat
      301 aaggcttatg acttactagc aagaattcac caagatttac ttgataataa aggtcgacaa
      361 gttgattttg aggctttgga taacctgttg gaacgactca aggatgtctc aagtgataaa
      421 gtcaagttag tggatgatat tcttgccttc ttagctccga ttcgtcatcc agaacgttta
      481 ggaaaaccaa atgcgcaaat tacctacact gatgatgaga ttcaagtagc caagttggca
      541 ggcaagtaca caacagaaga cggttatatc tttgatcctc gtgatataac cagtgatgag
      601 ggggatgcct atgtaactcc acatatgacc catagccact ggattaaaaa agatagtttg
      661 tctgaagctg agagagcggc agcccaggct tatgctaaag agaaaggttt gacccctcct
      721 tcgacagacc atcaggattc aggaaatact gaggcaaaag gagcagaagc tatctacaac
      781 cgcgtgaaag cagctaagaa ggtgccactt gatcgtatgc cttacaatct tcaatatact
      841 gtagaagtca aaaacggtag tttaatcata cctcattatg accattacca taacatcaa
//
LOCUS       DAVMCN010000136          898 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVMCN010000136 DAVMCN010000000
VERSION     DAVMCN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..898
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.137"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            95..277
                     /locus_tag="VYP85_002094"
     CDS             95..277
                     /locus_tag="VYP85_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1882524.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            287..649
                     /locus_tag="VYP85_002095"
     CDS             287..649
                     /locus_tag="VYP85_002095"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1882525.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKTGVKSK"
     gene            646..>898
                     /locus_tag="VYP85_002096"
     CDS             646..>898
                     /locus_tag="VYP85_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1882526.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDK"
BASE COUNT          373 a          113 c          151 g          261 t
ORIGIN      
        1 atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat attctgataa
       61 cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata agagccatta
      121 tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg atttgtatca
      181 aaataaaggt cgttttttat acaaatatgc tggttcattt ttagaagaag ctgcagtact
      241 atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc ctaattctga
      301 aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggagaaaaac acgcatacga
      361 aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac acactagaat
      421 aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact atccaaatag
      481 aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta ttggagggaa
      541 atattatgga gattctgcct gggaacattt aagagcagtg accggtattg atttacttag
      601 tattctaaca gatattgcaa ataaaaaaac aggggtaaaa tcaaaatgac agtattaaaa
      661 ggagataact tagaaatatt aaaaactatt gaatcctcaa gtattgattt aatctatatg
      721 gaccctcctt tctttacaca gaaaacccaa aaattatcta ataacaaaaa tattatgtat
      781 tcattcgaag atacgtggac ttcgattgag gattacaaag aatttttgtc tgtaagatta
      841 gaagaatgca aaagagtgct aaaaaatagt ggcagtattt tcgttcattg tgataaaa
//
LOCUS       DAVMCN010000137          867 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVMCN010000137 DAVMCN010000000
VERSION     DAVMCN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.138"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..860
                     /locus_tag="VYP85_002097"
                     /pseudo
     CDS             1..860
                     /locus_tag="VYP85_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
BASE COUNT          315 a           73 c          184 g          295 t
ORIGIN      
        1 actaattatt ttttatatat gttaaaaaaa cttgacaaga atggatttgg aaaggttaag
       61 acagtgataa catgccatgg atgggttgaa tataacttaa aaaagaaatt cttgacttat
      121 tttgattttt ggacatattc tatgggagat gcttttattt gtgtatctga aactatgaaa
      181 aaaagattgg agagtataat aaaaaataag aagatagttg caataaataa cggaattaat
      241 gtatcaaata gcgatttaga tgtagtaggt gttcaagact ttaaaaaaga attttgtatt
      301 ccaaataaca aaaaaatcat ttgttatgtt ggaaggttgg atccagaaaa aaggccggat
      361 agattccttg aatttgcaga aaaattattt ttagtcagag aagatgtgat ttttattatg
      421 gctggaaatg gtagtatgtg ggctgctttg aaagaaaaaa tttgctattt gaaatgtaga
      481 gataatttca ggttacttgg tgaaatctat ccagtactat agtttaccaa atatcggatt
      541 tattgtatat tccttctgat acagaaggaa tacctatgtg tgttttagag tcaatgtcac
      601 aaggaactcc ggttttagct agtaatgttg gcgggttaag tgaaattatt gaacataggg
      661 ttgatggatt tttatttgag aaggaagatg ttgagggagt gtgtgcttgt gctaattttt
      721 tactcaatga ttctgagtat ttgaaatata taggtgagaa tagtaaatca aaaataagaa
      781 aacatttttc tgtgcaaaaa atgtttgtag aaaccatgag agtatatgat gaattattag
      841 agaagagtag tcatggatag gaatata
//
LOCUS       DAVMCN010000138          857 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVMCN010000138 DAVMCN010000000
VERSION     DAVMCN010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.139"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..857
                     /locus_tag="VYP85_002098"
                     /pseudo
     CDS             1..857
                     /locus_tag="VYP85_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
BASE COUNT          349 a          120 c          159 g          229 t
ORIGIN      
        1 aagattattt taaaaataag gaagtcgttg cttcagaagg attagagaat ttacaggaac
       61 agtaccatgc tttccaagaa gaacgagata aggataaagt atccactgaa gagattgaga
      121 aagcctttaa gacatttaag gaaaaatgag ataccgttcg tgaatttgaa gtggaacttg
      181 cagagaacca aatagagaag ctagttgata agggcgtcta tatcaaggtg tctttcggtg
      241 tcaaacagag cggtcttatt ttcattccca actatcaatt ggatattatg gaagaagaaa
      301 atcataaaaa atataaagtc tacattcgag aaacgtcttc ttactttgtc tataataaag
      361 aaaacatgga taataattgt ttcatcaagg gtaggacctt aatcagacaa ttgagcaacg
      421 atagccaaaa actcccctat agacgaccaa ctttaaaaag tcttcaagag aagatttctg
      481 aaattaatct tatgattgaa ctatctaaca cgaacaaaca ataccaagaa atcaaagatg
      541 agcatgtatt agaaattgca gagattgata tgaagctaga agaaacccaa gaaaaaatcg
      601 ccaccttaaa caagatggcg gaagtcctta tcaatttgaa gagtgaagat catgagacta
      661 gaaaattagc taagtatgat tttgaccaaa tgaacatgac ggaatcaata atgttagatc
      721 gactcaatac agatatttta aaattacaac aggaacttgg taatgaaatt aataaatatg
      781 aggagatagc tagaagattg gatttgtttg tgaaaattat taataccaat aaatttacag
      841 ttctaaaatt tcacgag
//
LOCUS       DAVMCN010000139          809 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVMCN010000139 DAVMCN010000000
VERSION     DAVMCN010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.140"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>809
                     /locus_tag="VYP85_002099"
     CDS             <1..>809
                     /locus_tag="VYP85_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1882527.1"
                     /translation="MIANISTIGFGAYDRYRSKVHPKGDNLNKFVEDNVREAAKRFRD
                     HYDYWYKILEPENREKLYRSLLVYDAFKFGRDNTEDKVTYQADFETDHPAIKYFFGPA
                     GNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLG
                     PEFYAKGLLQAPDHPYDPTITINSVLKYDDSENSTRLQVADPTQRFNSAEDLHNYMHN
                     MFDLIYTLEILEGRAVAKLDYNAKNDLLRKIENKYKQDPDGNSVYATNVVR"
BASE COUNT          304 a          103 c          156 g          246 t
ORIGIN      
        1 ttatgatagc gaatatttca acaataggat ttggtgctta tgatagatat agaagtaaag
       61 tccatcctaa aggagataac ttaaataaat ttgtagaaga caatgtaaga gaagctgcaa
      121 aaagatttag agatcattat gattattggt ataaaatatt agagcctgag aatagagaga
      181 aactttatag aagtttatta gtatacgatg catttaaatt tggtcgagat aatactgaag
      241 ataaagtaac ttatcaagct gattttgaaa ctgatcatcc agctataaaa tacttctttg
      301 gacctgcggg gaataatgtt gttcataatg gacacggagc atatgctacc ggagatgcat
      361 tctattatat ggcatatcgt atgttggata aagatggagc tgtaacatat actcatgaaa
      421 tgacacataa ctctgataga gaaatttatc ttggaggata tggaagaaga agcggattag
      481 ggcctgagtt ttatgctaag ggcttattac aagcacctga ccacccatat gatccaacaa
      541 taacaattaa ctctgtgttg aaatatgatg attcagaaaa ttcaacaaga cttcaagtag
      601 ctgatccaac tcaacgattt aatagtgcag aagacctaca taattatatg cataatatgt
      661 ttgatttaat atatactctt gaaatattag aaggtcgtgc tgtagctaaa ttagattata
      721 atgcgaaaaa tgatttatta agaaaaattg agaataaata taagcaagat ccagatggta
      781 attctgttta tgcgacaaat gttgttcgc
//
LOCUS       DAVMCN010000140          755 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVMCN010000140 DAVMCN010000000
VERSION     DAVMCN010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.141"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..691
                     /gene="galE"
                     /locus_tag="VYP85_002100"
     CDS             <1..691
                     /gene="galE"
                     /locus_tag="VYP85_002100"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1882528.1"
                     /translation="MKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQY
                     IEVLLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLP
                     YLNIFGVDYSTPDGTCIRDYVHVNDLAYGHRKALEYIFNTDEGLYEVINLGSGVGFSV
                     FEILHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWK
                     WQQKHPNGYDD"
BASE COUNT          264 a           96 c          156 g          239 t
ORIGIN      
        1 aatgaaaaaa tataaggtat ttaattttgt gtttagttca tcagctactg tatacgaaag
       61 tactcctatc atgccattct atgagactaa tccattaaaa gcttcaaacc cgtatgggag
      121 aacaaaacag tatatagaag tacttttaaa tgatttgttt atttcgaatt caaattggaa
      181 aattgtttgt ctgaggtatt ttaatccatt gggtgcacat gaaagtggtg atttaggaga
      241 ggatccaaat ggaattccga ataatcttgt tccttacatt acacaagttg caattggaaa
      301 attaccatat ttaaatatat tcggagttga ttacagtact cctgatggga cttgtataag
      361 ggactatgtt cacgttaacg atttagcata cggacacaga aaagcattag agtatatttt
      421 taatacagat gaaggtttat atgaagtaat caatttagga agtggtgttg gttttagtgt
      481 atttgaaatc ctacacagct tagagagtgt cataggctcg tatattccat ataagataac
      541 ttcaaggaga gcaggagata tggacgtttc aattgcagat atttcaaaag cagaagagct
      601 actgggatgg aagccaaggt atgatattat gaaaatgtgc caagatacgt ggaaatggca
      661 acagaaacat ccaaatggat atgatgacta ataattgaaa ggattgggat taacatgcat
      721 atagtattat ttagatattc tgcacgggtt gttaa
//
LOCUS       DAVMCN010000141          615 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVMCN010000141 DAVMCN010000000
VERSION     DAVMCN010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.142"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..553)
                     /locus_tag="VYP85_002101"
     CDS             complement(<1..553)
                     /locus_tag="VYP85_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1882529.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYM"
BASE COUNT          214 a          123 c           77 g          201 t
ORIGIN      
        1 ccatataact aaccatacta ctatcactta catatgggaa atcctcataa tatattactt
       61 tataacgcat aaattcaagc gcccttccaa tactattcac aaaaacatga tcaacatggt
      121 caccaagtga aagcggacaa tatacgacac atttatcgtc taaatgcatt aacagctctt
      181 ttatgatatc attctttaat gtgtcctcat tttttaattc actatagata tgacggtata
      241 gaaaattgcc atttctatct ttcctataga gacattcata gtacgataag tgtctaaaat
      301 cacattgtag acgttcacaa gctaacctgt cttctttctt cctttcttca atcggatatt
      361 tcccaaggtt acacaactta tgaaattgct tagcagaggg ctgtagctgt tggctcaaag
      421 ggtaaccaga aaatatagta ataacaagta caatttctcc ttctgaagtt aattttgaaa
      481 tataatcact acaggaaaaa attgcgtcat ctaaatgtgg agataaaaag atatacttag
      541 tattgttact cataaccatt ccctctacaa tttatctaaa aactcactaa gtgtctgatt
      601 aaattccaca tcatc
//
LOCUS       DAVMCN010000142          605 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVMCN010000142 DAVMCN010000000
VERSION     DAVMCN010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.143"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            83..445
                     /locus_tag="VYP85_002102"
     CDS             83..445
                     /locus_tag="VYP85_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1882530.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKTISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          200 a           79 c          108 g          218 t
ORIGIN      
        1 atctacaacc tcaaaacagt gttttgagca acctgaggct agtttcctag tttgctcttt
       61 ggttttcatt gagtataaca gattgttaga agttggttta aatttcctaa tcagtttgtt
      121 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      181 tcatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaacaatatc
      241 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      301 cgtaaatggt actgctattc tttatcatta tttacgttct attgtttcaa tagtttcggc
      361 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      421 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      481 aaaagcagta agaaaaatgt cttgcattat acagcaacct tttgggaatg agtagatgga
      541 ttgaataaaa ttttattaag agtggatgat ttatctgtag attattattg gacagttagt
      601 cttga
//
LOCUS       DAVMCN010000143          586 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVMCN010000143 DAVMCN010000000
VERSION     DAVMCN010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.144"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            70..306
                     /locus_tag="VYP85_002103"
     CDS             70..306
                     /locus_tag="VYP85_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882531.1"
                     /translation="MNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKL
                     PKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            290..586
                     /locus_tag="VYP85_002104"
     CDS             290..586
                     /locus_tag="VYP85_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882532.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
BASE COUNT          254 a           58 c          108 g          166 t
ORIGIN      
        1 aattcaaata atgtaattga tagtaaccag aagaacggag agtttaactc aagtaaagat
       61 aatagacaaa tgaatgacaa gatcgacaat aaacaagata ataagacaga agaagtaaac
      121 tataaaatag ttggagatgg cagagaaact gaaaatcata ttaataaatc taaagaaata
      181 gtagatgtaa aacaaaaatt accaaagact ggttcgaaca agattatgga actattctta
      241 acagtgacag gaattggttt acttttgaca ctaaaagggt tgaagtatta tggtaaagat
      301 aaataaaatt tgttcgatac aaggaagttc cgtagaaaat gaggatattg taggttcaca
      361 aaatcagtat ttttggatta ttggtggagc tacagattta tataattcta aagaggagat
      421 aggttattca gtctcagaag ttgtacatat tttatcagaa agtttgtcgg ttaattgtaa
      481 agaatcaaaa actcttaaac aaatatttga aactgcttta ctcgaggtta aagatgaaat
      541 cggtttaaac tcatatgaat taacagagta taataaaatg aaataa
//
LOCUS       DAVMCN010000144          519 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVMCN010000144 DAVMCN010000000
VERSION     DAVMCN010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.denovo.145"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            279..>519
                     /locus_tag="VYP85_002105"
     CDS             279..>519
                     /locus_tag="VYP85_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882533.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQTGVFILEDFRNILLYNDV"
BASE COUNT          170 a           83 c           88 g          178 t
ORIGIN      
        1 aatatttcta gaaattaatt tgactttcct aatcgatttg ttcacatctt gtttcaatct
       61 actatacttt ctcgttaaac cgttcggcaa ttcatggtga catggacaca tggtagtaag
      121 cacactatgt ggcttggcag agctaaaaac tgttcccttg caataagcct aataagcaca
      181 acatagggag ttagagaagc cgactctaat caaccacttt gggcaatagt gagaactgcc
      241 ctgtgctttt ttattttgaa aaaatatgga gtttgtcgtt gaaattactt gattgtattt
      301 tggactatca agaaagattc aatggaaaaa catgtcaagt atcaacgaat tataagtatt
      361 tagagatttt caaagtgaat ttttgcttga ctgatttaca tcatttattt ggcttacaca
      421 aaatcacacg agattatgct agtcaaacaa aacctgctat tcaaactggt gtttttattt
      481 tagaagattt tagaaatatc ctattgtaca atgatgtaa
//
LOCUS       DAVMCN010000145        13622 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00044159
            SAMN33607323-rid17938803.guided.042, whole genome shotgun sequence.
ACCESSION   DAVMCN010000145 DAVMCN010000000
VERSION     DAVMCN010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607323
            Sequence Read Archive: SRR23725406
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721283.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721283.1
            Genome Coverage       :: 138x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 22:36:45
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,119
            CDSs (total)                      :: 2,075
            Genes (coding)                    :: 1,967
            CDSs (with protein)               :: 1,967
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 108
            CDSs (without protein)            :: 108
            Pseudo Genes (ambiguous residues) :: 0 of 108
            Pseudo Genes (frameshifted)       :: 54 of 108
            Pseudo Genes (incomplete)         :: 50 of 108
            Pseudo Genes (internal stop)      :: 31 of 108
            Pseudo Genes (multiple problems)  :: 21 of 108
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607323-rid17938803.guided.042"
                     /strain="AUSMDU00044159"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2020"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..65
                     /locus_tag="VYP85_002106"
     CDS             <1..65
                     /locus_tag="VYP85_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV1882534.1"
                     /translation="NVDKTSTVLKQTKNSDYADK"
     gene            190..927
                     /gene="erm(B)"
                     /locus_tag="VYP85_002107"
     CDS             190..927
                     /gene="erm(B)"
                     /locus_tag="VYP85_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV1882535.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(1184..2431)
                     /locus_tag="VYP85_002108"
     CDS             complement(1184..2431)
                     /locus_tag="VYP85_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1882536.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            2611..2832
                     /locus_tag="VYP85_002109"
     CDS             2611..2832
                     /locus_tag="VYP85_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1882537.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            2949..3446
                     /locus_tag="VYP85_002110"
     CDS             2949..3446
                     /locus_tag="VYP85_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV1882538.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            3421..3927
                     /locus_tag="VYP85_002111"
     CDS             3421..3927
                     /locus_tag="VYP85_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1882539.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            3911..6358
                     /locus_tag="VYP85_002112"
     CDS             3911..6358
                     /locus_tag="VYP85_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1882540.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            6361..8538
                     /locus_tag="VYP85_002113"
     CDS             6361..8538
                     /locus_tag="VYP85_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1882541.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            8535..9536
                     /locus_tag="VYP85_002114"
     CDS             8535..9536
                     /locus_tag="VYP85_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV1882542.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            9533..10465
                     /locus_tag="VYP85_002115"
     CDS             9533..10465
                     /locus_tag="VYP85_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1882543.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            10710..10826
                     /locus_tag="VYP85_002116"
     CDS             10710..10826
                     /locus_tag="VYP85_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV1882544.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            10842..12761
                     /gene="tet(M)"
                     /locus_tag="VYP85_002117"
     CDS             10842..12761
                     /gene="tet(M)"
                     /locus_tag="VYP85_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV1882545.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            12880..13047
                     /locus_tag="VYP85_002118"
     CDS             12880..13047
                     /locus_tag="VYP85_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV1882546.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(13107..13460)
                     /locus_tag="VYP85_002119"
     CDS             complement(13107..13460)
                     /locus_tag="VYP85_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1882547.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
BASE COUNT         4413 a         2419 c         2754 g         4036 t
ORIGIN      
        1 gtaatgtaga taaaacatct actgttttga aacagactaa aaacagtgat tacgcagata
       61 aataaatacg ttagattaat tcctaccagt gactaatctt atgacttttt aaacagataa
      121 ctaaaattac aaacaaatcg tttaacttct gtatttgttt atagatgtaa tcacttcagg
      181 agagattaca tgaacaaaaa tataaaatat tctcaaaact ttttaacgag tgaaaaagta
      241 ctcaaccaaa taataaaaca attgaattta aaagaaaccg ataccgttta cgaaattgga
      301 acaggtaaag ggcatttaac gacgaaactg gctaaaataa gtaaacaggt aacgtctatt
      361 gaattagaca gtcatctatt caacttatcg tcagaaaaat taaaactgaa tactcgtgtc
      421 actttaattc accaagatat tctacagttt caattcccta acaaacagag gtataaaatt
      481 gttgggaata ttccttacca tttaagcaca caaattatta aaaaagtggt ttttgaaagc
      541 cgtgcgtctg acatctatct gattgttgaa gaaggattct acaagcgtac cttggatatt
      601 caccgaacac tagggttgct cttgcacact caagtctcga ttcagcaatt gcttaagctg
      661 ccagcggaat gctttcatcc taaaccaaaa gtaaacagtg tcttaataaa acttacccgc
      721 cataccacag atgttccaga taaatattgg aagctatata cgtactttgt ttcaaaatgg
      781 gtcaatcgag aatatcgtca actgtttact aaaaatcagt ttcatcaagc aatgaaacac
      841 gccaaagtaa acaatttaag taccattact tatgagcaag tattgtctat ttttaatagt
      901 tatctattat ttaacgggag gaaataattc tatgagtcgc ttttttaaat ttggaaagtt
      961 acacgttact aaagggaatg gagataaatt attagatata ctactgacag cttccaagaa
     1021 gctaaagagg tccctagcgc ctacggggaa tttgtatcga taaggggtac aaattcccac
     1081 taagcgctcg ggaccccttg taggaaaatg tcctaagtgg gatatctgtc aactggtatg
     1141 gttgactaaa aatacttcct acgaaaatgt agggggtatt tttttacgaa aaaatacaat
     1201 cgattcttaa aaagaaaaat ttttgattgg caaaaccata acaagttcgt tttagggttt
     1261 tgattttgcg attgatgcct tctaaaggac cattagagta ttcaaattta gcgctattta
     1321 agacatattt tctgttttga cgaagggttt gaatagcagt atccatttct gtattggttt
     1381 tttggtagtc taagatggtt gactctagta attcactatt gcgctcgttt agggctttcg
     1441 tgatatcttg gtaagtttgg tatacttcag cgaacttgga aaatttacta gtaatgagat
     1501 caacagcatt ttggcgagtc atatattgtt taacgccgcg aagaaaaact acttcttcag
     1561 ggtgaagatc ttcagctttt ttatggaata gcttccaatg tgacttcata attttatatt
     1621 cttggctctg tttatcaagt tgctttagga tagagatacg acaattgtcc aaagcgcgac
     1681 cagctaattg tacaaggtgg aagcgatcaa taatgatatt ggcattaggg aaaaggcgat
     1741 agataaaact ttgatattga gcatttaaat caattacaac tgattgaacg cattcgcgtt
     1801 cggcttttga ataacgactt tcaaaataat caacaatggt aggtgataga cgatcctgta
     1861 actttgtgac aatttggtgg gtttcagcgt cacaacagat aaaggacatc acagacttaa
     1921 ttgaacgaaa ctcgtcaaaa catagatgct taggcaactt agccacacga tagtgtggtt
     1981 ccatgcgctc taagattgtt cgacgaacac tgctaggaga gcagtgacac atttcagcaa
     2041 taagctgacc agataagcct ttacgagcta aaagcatgat ttgatttttg agatcactgg
     2101 ataaggtttg attttctttg gttaaattag taatagcacc aaaagtagta tggcatgatt
     2161 tacatttata gcgttgttta cgaagctcta gttcatatct tctcccattt aaacttgcca
     2221 gtcgtacatg agttttgcga aagccatcct tattaactgt gggaaagcca cagttacgac
     2281 aacgattaat cggataagaa agagtagctg ttattagcgt tatatactct ttaacagaat
     2341 cgttgttgtg ttcagcttct tcaacagaaa taattttaat atttttatct ttaattccaa
     2401 gaatatttag gatagaatca ttatgggaca tttgtttaac cttctttcat gatttttgtg
     2461 gtgaattgat tgtataacga ggggacagca aatgtcctct tttttgtata aaaaaatctg
     2521 gcatggaatc tctatccata ccagaaagtg tataccccaa aaaaataact caaatacaaa
     2581 ttcattgaat atagagagga gaacattttt atgaattttg gacaaaacct ttataactgg
     2641 tttctatcaa acgctcaatc actggtgctt ttagcaatcg ttgtgattgg cttgtatctt
     2701 ggcttcaagc gtgagtttag caaactgatt ggctttttaa ttattgcgat tattgcggtt
     2761 ggcttagtct tcaacgctgc tggagtaaaa gacattttac tagagctatt caatcgcatt
     2821 attggtgctt aaataaaacc gttcttttgt ggaatataag tggttttctt atgttccgca
     2881 aaggaatggt acaccaaacg aagtgcggta gggatttttg aatctctaca aagaaaggac
     2941 gtgaatatat ggacgatatg caagtctata ttgcgaattt aggcaaatac aatgagggcg
     3001 aattggtcgg tgcgtggttt acctttccca ttgactttga ggaagtcaaa gagaaaatcg
     3061 gcttgaatga tgaatatgag gaatacgcca ttcatgacta cgagttaccc tttacggttg
     3121 acgaatacac ttccattggc gaactcaatc gactatggga aatggtatcg gaattacccg
     3181 aagaattaca atcggagcta tctgctctgc tcactcattt ttcaagcatt gaagaactaa
     3241 gcgaacatca agaggatatt atcattcatt ccgattgtga tgatatgtat gacgtggcac
     3301 gctactacat tgaagaaacg ggtgctttag gcgaagtacc agctagtctt caaaactata
     3361 ttgattatca agcctatggt cgggatttag acctttcagg aacgtttatc tcaaccaatc
     3421 atgggatttt tgaaatcgtc tattaaatct gtcggtacat tactactggc agattttcta
     3481 ttttacgggg tggctcaatc agctacccct attttttatg aaaggattga ttacatgaag
     3541 aaaatacgaa gctataccag tatctggtct gtggaaaagg tactgtattc tatcaatgat
     3601 tttagacttc cgtttcccat aacctttacg caaatgacat ggtttgtcgt gtcactcttt
     3661 gcagtgatga tacttggcaa cttgccccct ctttccatga tagagggagc atttctcaaa
     3721 tactttggga ttcctgtggc tttcacatgg tttatgtcta caaaaacttt tgatggtaaa
     3781 aagccttatg gatttttgaa gtctgtcatt gcttatgcac tgcgaccaaa gctgacctat
     3841 gcaggaaaaa aagtaacgct tggcagaaac cagccacaag aagccattac agcagttagg
     3901 agtgaatttt atggcatatc caattaaata cattgaaaac aatctcgtct ggaataaaga
     3961 cggggaatgt tatgcttact atgagcttgt tccttacaat tactcatttc taagtccaga
     4021 acagaaaata caagtgcatg attctttcag acagcttatc gcacaaaatc gtgatggcaa
     4081 aattcatgct ttacaaatca gtacagaatc cagcatacgt tctgcacaag agcgttccaa
     4141 aaatgaagtc actggcaagc tcaaagcggt tgcctatgac aaaatcgacc aacagacaga
     4201 cgctttaata tccatgattg gcgaaaatca agtgaactac cgtttcttta tcggctttaa
     4261 gttgcttctc aacgatcagg agttttctat gaaaagtctt accgttgaag caaaaaatgc
     4321 tttgtctgat tttgtctatg atgtgaacca taagctgatg ggcgattttg ttagtatgag
     4381 taatgatgaa atcctgcgtt ttcagaagat ggaaaagctc ttagaaaata aaatctctcg
     4441 tcgtttcaaa atccgcaggt tagataagga cgacttcggc tatctgattg aacaccttta
     4501 cggacagaca ggcactgcct atgaagagta tgagtaccat ctatcaaaga aaaagctgga
     4561 taatgaaacg ctgattaaat actatgactt gattaagcct actcgctgtt tggtggaaga
     4621 aaaacagcga tatttgaaaa tccagcagga agatgaaacc gtctatgtag cttactttac
     4681 cattaacagc attgtcggag aactggactt cccgtcctct gaaatcttct actaccagca
     4741 acagcaattt acattcccga ttgatacgtc aatgaatgtg gaaattgtag cgaatcgtaa
     4801 agccctatct actgtccgca ataaaaagaa agaactgaaa gacttggata accacgcttg
     4861 gcaaagtgat aatgaaacca gctccaatgt ggcggaagct ctggaaagtg tgaatgagct
     4921 ggaaaccaat ttagaccaaa gcaaggaatc tatgtacaag ctgtcttatg tggtaagggt
     4981 atcagcaaat gatcttgacg aactcaaacg tcgttgtaat gaagtgaaag atttttatga
     5041 cgatttaagc gtaaaactgg tacgaccatt tggggatatg ctcggcttac atgaagaatt
     5101 tttacctgcc agcaagcgtt atatgaatga ttatattcaa tacgtgacct ctgatttcct
     5161 cgctggttta ggttttggtg ctactcaaat gctgggggaa aatgagggga tttatgttgg
     5221 ctacagctta gatactggac gcaatgtcta tctgaaacct gctcttgcca gtcaaggggt
     5281 taagggttca gtaaccaatg cgttagcgtc ggcttttgtt ggttcgctgg gtggtggtaa
     5341 atcctttgcg aataacctta tcgtctatta tgcggtgctt tatggggcac aagcagtgat
     5401 tgtagaccca aaagcagaac gtggcagatg gaaagaaacc ttgccagaga tttcccatga
     5461 aatcaatatc gtcactctga cttctgatga gaaaaacaaa ggcttacttg acccttatgt
     5521 gattatgaaa aatcccaaag attctgaatc actggctatt gatattctga cattccttac
     5581 ggggatttcc tctcgtgatg gggaacgctt cccaatcctt agaaaagcca ttcgtgcagt
     5641 aaccaatagt gaagtacgag ggttgatgaa agtgattgag gaattacggg ttgagaatac
     5701 gccactaagt accagtatag ccgaccatat cgaaagtttt acagactatg actttgcaca
     5761 tttattattc agtaatggtt atgtggagca gtctatcagc ttagaaaaac aactgaacat
     5821 tatacaggtt gcggacttgg tacttcccga caaggaaact tcctttgagg aatataccac
     5881 tatggagctt ttatccgttg ctatgctgat tgtcattagt acctttgctt tagactttat
     5941 ccatacagac cgaagcattt tcaagattgt agatttagac gaagcatgga gctttttaca
     6001 ggtagcacaa ggaaaaacac tatctatgaa gctggttcgg gctggtcgtg ctatgaacgc
     6061 tggggtatat ttcgtgaccc aaaatacaga cgacctctta gatgaaaaac tgaaaaataa
     6121 cctcggctta aaatttgcat ttcgttccac tgaccttaac gagattaaaa agaccttagc
     6181 cttttttggt gtagacccag aggacgaaaa caatcagaag cgattgcgtg atttggaaaa
     6241 cgggcaatgc cttatcagtg atttatatgg tcgtgtcggt gtgatacagt tccaccctgt
     6301 atttgaagaa ctgctccatg cctttgatac cagaccacct gtgcgaaaag aggtgtaaat
     6361 gtgaaaccat caatagtaaa cagaataaaa tcaaactgga cgctgaaacg tctaggtaaa
     6421 gtggcaatga cagtggcttt cacacttgtg attgccattt ttcttttagc catgctggga
     6481 acggtggttc aagctgcggg cttggtagat gatacggtca atgtggcaaa tgaatacagc
     6541 cgatacccac ttgaaaacta tcaactggat ttttatgtgg ataatagctg gggctggctt
     6601 ccgtggaact ggtcggacgg gattggaaaa caggtcatgt atggactata tgccattacc
     6661 aattttattt ggacaatcag tttgtatgtt tccaatgcga caggttactt agtacaggaa
     6721 gcctattcct tagacttcat ttccgctaca gcagattcca ttggtaagaa tatgcagacc
     6781 ttagctggtg tgagtgcaaa cggattttca acagagggtt tctatgttgg attcctctta
     6841 ctcttgattt tggttcttgg ggtttatgtt gcctatacgg gactgataaa gagagaaacc
     6901 acaaaggcaa ttcatgccat tatgaatttt gtgctggtgt ttatcctatc ggcttccttt
     6961 attgcctacg ctcccgacta cattaaaaaa atcaatgact tttcatcaga catcagtaat
     7021 gccagtttat cacttggcac gaagattgtc atgccccatt ccgatagtca aggcaaggac
     7081 agcgtggact taatcagaga tagcctgttt tccatacagg ttcagcaacc gtggctactg
     7141 cttcaataca acagttcaga cattgaaagt atcggtattg accgtgtgga aagcctgctc
     7201 tccaccagcc cagattccaa caatggcgaa gacagagaaa aaattgttgc ggaagaaatt
     7261 gaagacagaa gcaataccaa tctaaccatt acaaagacca ttaaccgttt aggtacagtc
     7321 ttcttcctat ttgtcttcaa tattgggatt tccatatttg tattcctatt aacaggaatc
     7381 atgattttct cgcaggtact ttttatcatc tatgctatgt ttctgcctgt gagctttatt
     7441 ttaagcatga ttccatcatt tgatggtatg tcaaaacgag ccataacaaa gctctttaat
     7501 accattttga cacgagctgg aatcacattg attattacga cagcatttag tatttcaacc
     7561 atgctctata ccttatcggc tggttatccg ttctttttga ttgcttttct acagattgtg
     7621 acctttgcag gaatctactt caagctgggc gatttaatga gtatgttttc tctacagagt
     7681 aacgattctc aaagtgtggg aagtcgtgtg atgagaaaac ctcgtatgct tatgcacgct
     7741 cacatgcacc gtctacagcg gaaacttgga cgttccatga ctactctagg ggctgggtct
     7801 gccattgtta caggtaaaaa aggacagtcg ggttcgggga gttctgcaag gacacaagca
     7861 gatcactccc gaccagacgg aaaggaaaaa tcaacacttg gaaaacgtat cggtcaaacc
     7921 atcggtacag tagctgatac caaagacaga atggtagaca ctgctagtgg tttgaaagaa
     7981 caggttaaag atttgccgac caatgcaaga tatgcagtat atcaaggaaa atccaaagta
     8041 aaagagaatg tccgtgattt aaccagtagt atttctcaaa ccaaagcgga cagagccagt
     8101 ggacgcaagg aacagcagga acaaaggcga aaaaccattg cgaagcgtcg ctctgaaatg
     8161 gaacaggtca aacagaaaaa acagcctgct tcttctgttc atgaaagacc gactacaaga
     8221 caagaacaat atcatgatga acagacctca aaacagtcta atattcagac ttcatataag
     8281 gaatctcaac aagccaaaca agagcgtcca gcagttaagt ccgatttttc aagtccaaaa
     8341 gtggaacgcc aaggcaatac cgttcaagaa aaaaccgttc aaaagccagc aacttcaacc
     8401 actacagcag atagaacttc acaacgtcca atcacaaaag aacgtccgtc tactgttcaa
     8461 agagtaccac tacaaaatac aagaagtaga ccaccaatca aaaccgccac cattaagaaa
     8521 gtcggtaaga aaccatgaag ttgaaaactt tagtgattgg tggttctgga ttattcttga
     8581 tggtcttctc actgcttctg tttgttgcca ttttattttc agatgaacag gacagcggaa
     8641 tttccaatat tcattatgga ggtgtgaatg tttccgcaga agtgctggct cataagccta
     8701 tggtagaaaa atatgccaaa gaatatggcg ttgaagaata tgtcaacata cttcttgcga
     8761 ttatacaggt ggaatcgggc ggtactgcgg aagatgttat gcagtcctcg gaatccctcg
     8821 gtcttccacc taattcattg agtacagaag aatccattaa gcaaggtgtg aagtatttca
     8881 gtgaattatt agccagtagc gaaaggctca gtgtagattt agaatcggtt atccagtcct
     8941 acaattatgg tggtggtttc ttagggtatg tggctaatcg tggaaataaa tatacctttg
     9001 aactggctca aagtttctca aaagagtatt caggtggcga aaaagtgtct taccccaatc
     9061 ccatagccat acctatcaat gggggctggc gatacaacta tggcaatatg ttttatgtgc
     9121 aactggtaac gcagtatctt gtcacaacag agtttgatga tgatacggta caagccatca
     9181 tggacgaagc actgaaatat gagggctggc gatacgttta cggtggagct tccccgacta
     9241 cttcttttga ttgtagcgga ctgacacaat ggacgtatgg aaaagctgga attaacttac
     9301 cacgaaccgc acaacagcaa tatgatgtga cccagcatat cccactatcg gaagcacaag
     9361 ctggcgattt ggttttcttt cattctacct ataacgctgg ctcttatatt actcatgttg
     9421 ggatatacct tggcaataac cgtatgtttc atgcaggcga cccaatcggt tatgccgact
     9481 taacaagccc ctactggcaa cagcatttag tgggagcagg acgaatcaaa caatgagaaa
     9541 ggaagattta atgatgaaat ttagaaaaaa tcagaataaa gaaaaacaga taccaaagga
     9601 aaagaaacct cgtgtctata aggtcaatcc tcataaaaag gttgtgattg ccttgtgggt
     9661 acttttaggg cttagtttca gctttgcgat attcaagcac tttacagcta tagatactca
     9721 tactattcac gaaacaacta tcatagaaaa ggaatacgtt gatactcatc atgtagaaaa
     9781 ttttgtagag aactttgcga aagtctacta ttcatgggag caatccgata agtccattga
     9841 taatcgaatg gaaagtctaa aaggctatct gacagatgaa cttcaagctc tcaatgttga
     9901 tacagtacgc aaagatattc ctgtatcgtc ttctgtaaga ggatttcaga tatggacggt
     9961 agagccaact ggcgacaatg agtttaatgt aacctacagt gtagaccagc tcattacaga
    10021 gggagaaaat acaaagaccg tccactctgc ttatatagtg agtgtctatg tagatggttc
    10081 tggaaatatg gtactggtta agaatccgac cattaccaac atacctaaga aatcaagtta
    10141 taaaccaaaa gccattgaaa gtgaggggac ggttgattcc attacaacca atgaaatcaa
    10201 tgagttttta acgacgttct tcaagctcta tcctacagcg acagccagtg aactttccta
    10261 ctatgtgaat gacgggatat taaaaccaat cggaaaagag tacatctttc aagaactggt
    10321 aaatcctatt cacaatcgta aggataatca agtcacggta tcgctgacag tggagtatat
    10381 cgaccagcag accaaagcaa cgcaggtatc tcaatttgat ttggtacttg aaaagaacgg
    10441 gagtaattgg aagattgtaa aataacaaat attggtacat gattacagat actttgtaat
    10501 catgtactct ttttgataaa aaattggaga ttcctttaca aatatgctct tacgtgctat
    10561 tatttaagtg actatttaaa aggagttaat aaatatgcgg caaggtattc ttaaataaac
    10621 tgtcaatttg atagcgggaa caaataatta gatgtccttt tttaggaggg cttagttttt
    10681 tgtacccagt ttaagaatac ctttatcatg tgattctaaa gtatccagag aatatctgta
    10741 tgctttgtat acctatggtt atgcataaaa atcccagtga taaaagtatt tatcactggg
    10801 atttttatgc ccttttgggt ttttgaatgg aggaaaatca catgaaaatt attaatattg
    10861 gagttttagc tcatgttgat gcaggaaaaa ctaccttaac agaaagctta ttatataaca
    10921 gtggagcgat tacagaatta ggaagcgtgg acaaaggtac aacgaggacg gataatacgc
    10981 ttttagaacg tcagagagga attacaattc agacaggaat aacctctttt cagtgggaaa
    11041 atacgaaggt gaacatcata gacacgccag gacatatgga tttcttagca gaagtatatc
    11101 gttcattatc agttttagat ggggcaattc tactgatttc tgcaaaagat ggcgtacaag
    11161 cacaaactcg tatattattt catgcactta ggaaaatggg gattcccaca atctttttta
    11221 tcaataagat tgaccaaaat ggaattgatt tatcaacggt ttatcaggat attaaagaga
    11281 aactttctgc cgaaattgta atcaaacaga aggtagaact gtatcctaat atgtgtgtga
    11341 cgaactttac cgaatctgaa caatgggata cggtaataga gggaaacgat gaccttttag
    11401 agaaatatat gtccggtaaa tcattagaag cattggaact cgaacaagag gaaagcataa
    11461 gatttcataa ttgttccctg ttccctgttt atcacggaag tgcaaaaaac aatataggga
    11521 ttgataacct tatagaagtg attacgaata aattttattc atcaacacat cgaggtccgt
    11581 ctgaactttg cggaaatgtt ttcaaaattg aatatacaaa aaaaagacaa cgtcttgcat
    11641 atatacgcct ttatagtgga gtactacatt tacgagattc ggttagagta tcagaaaaag
    11701 aaaaaataaa agttacagaa atgtatactt caataaatgg tgaattatgt aagattgata
    11761 gagcttattc tggagaaatt gttattttgc aaaatgagtt tttgaagtta aatagtgttc
    11821 ttggagatac aaaactattg ccacagagaa aaaagattga aaatccgcac cctctactac
    11881 aaacaactgt tgaaccgagt aaacctgaac agagagaaat gttgcttgat gcccttttgg
    11941 aaatctcaga tagtgatccg cttctacgat attacgtgga ttctacgaca catgaaatta
    12001 tactttcttt cttagggaaa gtacaaatgg aagtgattag tgcactgttg caagaaaagt
    12061 atcatgtgga gatagaacta aaagagccta cagtcattta tatggagaga ccgttaaaaa
    12121 atgcagaata taccattcac atcgaagtgc cgccaaatcc tttctgggct tccattggtt
    12181 tatctgtatc accgcttccg ttgggaagtg gaatgcagta tgagagctcg gtttctcttg
    12241 gatacttaaa tcaatcattt caaaatgcag ttatggaagg gatacgctat ggttgcgaac
    12301 aaggattata tggttggaat gtgacggatt gtaaaatctg ttttaagtat ggcttatact
    12361 atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta ttggaacaag
    12421 tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa atttatgcgc
    12481 cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg aacatcgtag
    12541 acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct cggtgtattc
    12601 aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt ttaacagagt
    12661 taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc
    12721 ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta tgttgttata
    12781 taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt gaattaaagt
    12841 gtaaaggagg agatagttat tataaactac aagtggatat tgtgtcctgt atgtggaaat
    12901 aaaacacgat taaagataag ggaagatact gaattaaaaa aattccccct ctattgtccg
    12961 aaatgcagac aagaaaattt aattgaaata aagcagttca aagtaactgt gattacagag
    13021 ccagacgcaa agacgcagag ccgataaaat gagattaata caatctcatt ttatcggctc
    13081 tttccgttat gtatggattc ttttaattag tcttcgatgt ttcttgcttc gttgataccg
    13141 ctggctaaag attccattaa ggatagttct ttgtctgtaa agctatccat gtatttctct
    13201 atctgtaatc gtcgggtgct ttttaccaag ttattagcag gtaagaaaaa ttcatcaacg
    13261 gaaacatgaa gtaacgatac aaggtcataa agaacttgta tgctggggtg ttgcccttta
    13321 ttttcaatat tagttaagta ccgtgggtca atttcaatca atgctcccac ttgttcacga
    13381 gttaaacctc gtttcaatcg agcttcttta atggctaaac caaaggctct aaaatcatat
    13441 ttatcttctt ttttacgcat agtagaccac ctctatacat tttattgttc ctactgaatt
    13501 aaaaacaggt atagaaaaac gtgttatatg gtttataggt ttatatttaa taaaaagcac
    13561 tactaaacgc caataaaaaa aaccgttata tggtagtgct atttacgctg ttaaaatatt
    13621 gt
//
